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A page from the PDF document.
AC Wharton, Jr. with Memphis & Shelby County Government.
A collaboration of MCA Students:
Myself & Katie Benjamin — Logo & Digital Implementation Plan
Eric Huber — Packaging
Bryan Rollins — CD Layout
James Hart — Broadside Design
“Transport Decarbonisation: Driving Implementation” project members meeting at the ITF in Paris, France, to help identify ways to cut CO₂ emissions in three hard-to-decarbonise areas of transport: aviation, shipping and heavy-duty road freight. Their successful transition to a low- and ultimately zero-carbon operation is vital to achieving the international community’s climate goals.
The ION-E simplifies implementation by using the structured cabling systems familiar to IT installers, along with providing a simple user interface for setup and configuration with minimal input.
Today’s modern buildings require flexibility to handle floor space layout changes, the relocation of users, or other changes that would require an extensive rework of the wireless system. As a multi-band, multi-operator and multi-technology platform, the ION-E employs a standard grid approach and supports on-demand software defined frequencies to flexibly adapt to changing requirements.
The ION-E platform easily scales to support buildings from 5,000 to 500,000 square meters. It is frequency agile and technology agnostic, eliminating the need for costly infrastructure and equipment upgrades.
Arvikaverken is a former Swedish producer of agricultural implements.
The company was founded in 1885, when Per Andersson started producing plows and chopping machines in Arvika. In 1888, the company was registered under the name P. Andersson. In 1889, the operation was expanded by Johan Igel's iron foundry being taken over, and the name was changed to P Andersson & Co Mekaniska Werkstad. The company grew rapidly, and in 1899 the name was changed again, this time to AB Arvika Werkstäder. In 1916 the name was changed to AB Arvikaverken.
In 1917, Arvikaverken joined AB Johan Thermenius and Son in Hallsberg, and the name was changed to AB Arvika-Verken. The company now focuses on the production of agricultural machinery, and developed into a large producer of plows, mowers and self-ties. The plows were produced in Arvika, while the mowers and binders were produced in Valla and Skurup. In 1946, the company resumed the production of combine harvesters, both towing and self-propelled machinery. These were produced in Hallsberg. In 1959, the name was changed to Arvika-Thermaenius AB.
In 1960, the company was acquired by Bolinder-Munktell in Eskilstuna. The purchase did not come because of poor finances, but more because of Bolinder Munktell's future plans. The production of wheel loaders and the belt trailer BV202 was added to Arvika. Arvikaverken is today part of Volvo Construction Equipment.
www.msn.com/en-us/money/markets/fda-lays-out-annual-covid...
FDA Lays Out Annual Covid Shot Plan Similar to Flu
(Bloomberg) -- Americans are about to get a clearer idea of how often they’ll roll up their sleeves for Covid-19 shots when advisers to US regulators meet Thursday to discuss an immunization schedule that looks more like the one used for flu.
The plan would have health officials meet each June to review which strains of the virus should be included in Covid shots to be deployed no later than September of the same year, according to documents released by the US Food and Drug Administration ahead of the Jan. 26 meeting.
Experts from around the world convene annually to make predictions about which flu strains will dominate during the upcoming season and, thus, should be targeted by shots. The FDA is looking for a similar coordinated effort to take place at least as often for Covid shots, one of several changes the agency hopes might help simplify the immunization process and encourage more Americans to stay up to date.
Waning immunity from vaccinations and the emergence of new variants every few months has led regulators to recommend variant-targeted boosters, a tactic that so far has been unpopular among Americans and has even split some health experts on costs and benefits. Just weeks after rolling out the updated BA.4 and BA.5 boosters in September, new mutations were rampant. Now, even as the US sees the rise of an immune-evasive variant called XBB.1.5, booster uptake is hovering at about 15%.
“Although the use of the bivalent mRNA boosters is supported by the available evidence, their deployment has been associated with significant implementation complexities,” the FDA said. Switching to one composition for both primary shots and boosters will help streamline the process, according to the agency documents.
Evidence suggests that immunity from prior exposure to the virus along with vaccination will provide enough protection so that most people will need one annual Covid booster, according to the documents. However, young children who might not have been previously exposed and people who are at higher risk for severe disease may need two yearly shots, the FDA said.
“An annual vaccine would be ideal because people would remember, they can do it with other vaccinations like flu and it can last,” Albert Bourla, chief executive officer of Covid vaccine-maker Pfizer Inc., said Jan. 18 in an interview with Bloomberg.
The FDA is still concerned about evasion of vaccine-induced immunity by mutants of the fast-spreading omicron strain, according to the documents. That warrants continued surveillance of variants and also monitoring of the protection previous vaccines provide against new strains.
Pfizer and Moderna Inc. are both working on next-generation vaccines that hold up against mutations and provide longer-lasting protection, but it’s unlikely those will be ready to go into arms anytime soon.
www.news-medical.net/news/20230123/SARS-CoV-2-Omicron-XBB...
SARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistance
In a recent study posted to bioRxiv* preprint server, researchers at Ohio State University examined the degree of neutralizing antibody (nAb) evasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB.1.5, CA.3.1, and CH.1.1 subvariants.
Several subvariants have emerged from SARS-CoV-2 Omicron, some showing relatively higher immune evasion, threatening vaccination efficacy. The BQ.1.1 sub-variant was the most prevalent following months of BA.5 predominance in the United States. Nonetheless, it is being quickly replaced by XBB.1.5. The XBB lineage was first detected in India as a recombinant of BA.2.75 and BA.2.10.1.1. Its emergence was alarming since it contained numerous mutations with established immune escape characteristics.
The effectiveness of monoclonal antibodies (mAbs), mono- or bivalent vaccines, and infection-induced immunity were reduced against XBB. The XBB lineage acquired two additional substitutions in the spike, resulting in XBB.1 and XBB.1.5 subvariants, and their impact remains unknown. In addition, the CA.3.1 and CH.1.1 subvariants of Omicron have been notable lately, as they carry the L452R substitution in the spike, previously discovered in the Delta and Omicron BA.4/5 variants.
The study and findings
In the present study, researchers evaluated the spike protein biology of emergent SARS-CoV-2 Omicron subvariants XBB.1.5, CA.3.1, and CH.1.1. First, they assessed the infectivity of spike-pseudotyped lentiviruses in HEK293T-ACE2 cells expressing human angiotensin-converting enzyme 2 (ACE2) and Calu-3 cell line. XBB.1 and XBB.1.5 had higher infectivity, with nearly two-fold increased titers than SARS-CoV-2 D614G in HEK293T-ACE2 cells.
XBB subvariants’ infectivity was not significantly different from that of D614G in this cell line. By contrast, CA.3.1 and CH.1.1 subvariants had nearly 2.5-fold lower infectivity than D614G in Calu-3. Next, the team tested neutralization of these emergent subvariants by sera from 14 healthcare workers (HCWs) boosted with a bivalent vaccine after two-to-four doses of monovalent mRNA vaccine.
Sera were obtained after a median of 66 days post-bivalent vaccination. CA.3.1, CH.1.1, and XBB.1.5 subvariants showed strong resistance to neutralization by sera relative to BA.4/5, with 4.6 to 17.7 times lower nAb titers than BA.4/5. Interestingly, XBB.1.5 had slightly higher nAb titers than its parent lineage (XBB).
Of note, BQ.1.1 showed higher neutralization resistance than any of the XBB subvariants, with 12.8 lower nAb titers than BA.4/5. The CA.3.1 and CH.1.1 subvariants displayed much higher resistance to neutralization by bivalent sera. Next, the neutralization experiments were repeated using sera from HCWs vaccinated thrice with monovalent mRNA vaccines.
Samples were obtained after 2-13 weeks post-vaccination. The mean nAb titers of triple-vaccinated sera against SARS-CoV-2 D614 and Omicron (BA.2 and BA.4/5) were up to 5.6-fold lower than those of bivalent sera. nAb titers were markedly reduced for CA.3.1, CH.1.1, and XBB.1.5 subvariants. Overall, the trends of triple-vaccinated sera in neutralizing subvariants were comparable to those of bivalent sera.
In addition, the team examined the neutralization resistance of subvariants to sera from individuals infected with BA.4/5. They observed potent and near-complete neutralization resistance for CA.3.1, CH.1.1, and XBB.1.1 subvariants, with 2.6 to 4.1-fold lower nAb titers than BA.4/5. Furthermore, the researchers determined fusogenicity, surface expression, and processing of spike proteins of the subvariants.
Reduced syncytia formation was evident for all subvariants relative to D614G. XBB.1 and XBB.1.5 showed no differences in spike fusogenicity compared to XBB. The efficiency of syncytia formation of CA.3.1 and CH.1.1 was lower than BA.2.75.2. XBB subvariants, BQ.1.1, and BA.2.75.2 exhibited higher spike processing than D614G. There were no differences in spike processing for CA.3.1 and CH.1.1 subvariants relative to the parental BA.2.75.2.
Finally, homology modeling of XBB lineage spikes complexed with ACE2 or nAbs was performed. The P486 residue in XBB.1.5 was more hydrophobic than the S486 residue in XBB/XBB.1, resulting in favorable interactions with residues in ACE2, which allows better receptor utilization. The residue 486 is a hotspot for class I nAb recognition, and mutations at this site in XBB subvariants completely abolish interactions with the therapeutic mAb, AZD8895. Mutations at K444 and L452 residues found in CA.3.1 and CH.1.1 also affect interactions with class II nAbs.
Conclusions
Taken together, the findings suggested that bivalent mRNA vaccines induce up to eight times higher nAbs than monovalent vaccines. XBB subvariants, CA.3.1 and CH.1.1, exhibited almost complete escape from neutralization by triple-vaccinated or BA.4/5 infection sera. Moreover, XBB.1.5 did not show enhanced immune evasion relative to BQ.1.1. CA.3.1 and CH.1.1 subvariants consistently showed higher resistance to neutralization than XBB subvariants, warranting continued surveillance and further analyses.
Valle del Cauca implementa programa de rehabilitación integral para personas en condición de discapacidad visual. Foto: Deywis Ayure Casas
A training of trainers of a South Sudan’s soon-to-be unified army concluded today, 4 October, with a graduation ceremony at the Military Training Centre in Luri near Juba.
The event marks a significant step forward for the implementation of the country’s revitalized peace agreement, signed in September last year.
Lieutenant General Shailesh Tinaikar, Force Commander of the United Nations Mission in South Sudan, described the project of training the nation’s unified forces as one with “tremendous implications for national integrity and security”. He called the graduating instructors “pioneers” with a “huge responsibility” to carry after having received just ten days of training.
“Whatever you do, however you act, is going to affect the soldiers who you train, so I implore you to be conscious of your actions, because you set the trend of the forces of South Sudan,” the Force Commander said.
Lieutenant General Tinaikar also stressed the importance of looking forward rather than backward.
“You have to forget your past, from where you come and your past affiliations, to work together for your young nation, for the state of South Sudan,” he said, reiterating his faith in the diligence and capacity of the instructors to train the unified forces properly.
A lack of qualified trainers has been slowing down the capacity building of units of the united armed forces in 35 cantonment sites across the country, making the readiness of instructors such a vital sign of progress.
To enable the establishment of a Transitional Government of National Unity on 12 November, the few hundred graduates will need to capacitate some 83,000 soldiers, the troops being merged from the South Sudan People’s Defence Forces and the Sudan People’s Liberation Army in Opposition.
Photo: UNMISS / Eric Kanalstein
The concept for the Army Innovation Hub is to accelerate Army innovation by using collaborative partnerships of government, industry and academia within a global network based at APG. (Image courtesy of ARL)
En el marco del proyecto implementando por la Organización Pan Americana de Salud / Organización Mundial de la Salud (OPS/OMS), financiado por la Dirección General de Ayuda Humanitaria y Protección Civil de la Comisión Europea (ECHO) para los migrantes, desde hace varios meses se viene trabajando en el municipio de Cúcuta.
En el corregimiento de Palmarito las acciones estuvieron enfocadas para que los habitantes cuenten con un Plan Comunitario para la gestión del riesgo de desastres y primeros respondientes en salud formados y dotados, que puedan desarrollar primeros auxilios físicos y psicológicos, contra incendio y vigilancia comunitaria de eventos de importancia en salud.
Con un simulacro de inundación finalizó una de las etapas del proceso comunitario. La jornada incluyó la limpieza a una quebrada que atraviesa el municipio y que ha sido utilizada por los habitantes para votar la basura. Según los pobladores, la prevención de los riesgos puede salvar vidas.
Fotografías Karen González
The Union Implement and Hardware Building was constructed in 1900, and was a joint venture by the Union Implement and Hardware Company (a seller of agricultural implements) and Fortitude Lodge No. 107. It was listed on the National Register of Historic Places in 1988. It is also a contributing property to the 2006 listing of the Independence Downtown Historic District.
The Masonic building is the blonde brick, three-story structure on the left. It was original home to the Odd Fellows from 1902 to 1939, hence the three links emblem on the the terra cotta parapet above the third floor. The Masons would move out in 1957.
Independence is the county seat of Montgomery County in southeastern Kansas just north of Bartlesville, Oklahoma.
A page from the PDF document.
AC Wharton, Jr. with Memphis & Shelby County Government.
A collaboration of MCA Students:
Myself & Katie Benjamin — Logo & Digital Implementation Plan
Eric Huber — Packaging
Bryan Rollins — CD Layout
James Hart — Broadside Design
Alkhidmat Foundation Pakistan Sindh chapter has implemented another Clean Drinking Water Project (Submersible Water Pump) at Village Kerti of UC Bhakou, District Tharparkar. Around 28 families are expected to benefit from the project.
From(Left to Right) Mr T Chitty Babu, Convenor, Infrastructure & Urban Development Panel, CII Chennai Zone and Chairman & CEO, Akshaya Pvt Ltd. Mr Amit Bansal, Director, Forensic Services, Infrastructure Sector, KPMG in India, Mr Ramesh Subramaniam, President, Sri City Pvt Ltd at the session on Project Implementation Risks in Infrastructure - Typical Misconduct Practices on 28th July 2010 at Chennai.
This Harrisonville, Missouri ghost sign reads "Hammar Paints, wagons & Implements,Champion Mowers & Binders
From 15th to 18th of July 2013, a workshop was held in Accra, Ghana to set EAF (ecosystem approach to fisheries) implementation baselines for 13 countries in the CECAF-south area.
from the museum of funeral customs. the interior is dimly lit with incadescents, but i wanted most of the pictures i took in there to look more antiseptic and clinical so i gelled the flash with a rosco Tough Plusgreen and overpowered the ambient lights, bouncing where i could to emulate ambient fluorescents. it was frustrating because the ceiling is high above the subjects and also painted matte black, making it impossible to bounce the light from above.
Flooding of the Marsaki Wadi (28th of August and 1st of October 2019) and the impacts of the flood on the Marsaki dyke that was constructed to protect the communities of the Marsaki area of Tadjourah city from the floods.
Learn more about UNEP's work on adaptation: www.unep.org/explore-topics/climate-change/what-we-do/cli...
Photo credit: Ministry of Habitat, Urbanism and Environment, Djibouti
El Gobernador del Estado, Carlos Lozano de la Torre, recibió de manos del Secretario de Gobierno, Sergio Reynoso Talamantes, el plan de acciones y estrategias que Protección Civil implementará con motivo de las fiestas de fin de año
Con la finalidad de reforzar las medidas preventivas y que la población de Aguascalientes goce de unas fiestas de fin de año con seguridad y tranquilidad, la Coordinación Estatal de Protección Civil elaboró ya el plan que integra las acciones y estrategias a implementar durante el 31 de diciembre y el 1 de enero, mismo que fue entregado al Gobernador del Estado, Carlos Lozano de la Torre por el Secretario de Gobierno, Sergio Reynoso Talamantes.
Este plan integra un operativo especial de vigilancia y supervisión en caminos y carreteras de la entidad, mismo que ya estaba contemplado dentro del Plan Estatal de Contingencias por Temporada de Invierno, y en el que se exhorta a los aguascalentenses que pongan en práctica la autoprotección, con lo que se garantiza que todos tengan un cierre de año seguro.
El operativo ha estado activo desde el 27 de diciembre y concluirá el 7 de enero, pero será el 31 de diciembre y el 1 de enero cuando se intensifiquen los recorridos de supervisión en el que participan las once Unidades Municipales de Protección Civil, y todos los Servicios de Emergencia, enfatizando que se mantendrán atentos a las carreteras, debido al incremento de la afluencia vehicular en ellas durante estas fechas.
La Coordinación Estatal de Protección Civil ha solicitado a la ciudadanía que durante estas fechas conduzcan con precaución, sin haber ingerido bebidas alcohólicas y que respeten los límites de velocidad.
También existen recomendaciones para quienes pasarán las fiestas de fin de año fuera de sus casas, como desconectar todos los adornos navideños eléctricos, cerrar el paso de gas L.P. y notificar a un vecino de confianza que la casa estará sola; aunado a esto, se le recuerda a la población que el 9 10 20 20 de Locatel y el 066 se encuentran disponibles las 24 horas para que se reporte cualquier emergencia.
William Francis Morneau, Minister of Finance of Canada capture during the Session: Implementing Strategies for Inclusive Growth at the Annual Meeting 2018 of the World Economic Forum in Davos, January 23, 2018
Copyright by World Economic Forum / Sikarin Thanachaiary
18 June 2014, Smart Specialisation Strategies: Implementing European Partnerships
Belgium - Brussels - June 2014
© Committee of the Regions / Wim Daneels
Yes. This is the trash can where Nick Montfort and Scott Rettberg were questioned about photographing. I was a little nervous about it before I came into the city, but it was all cool. Nobody even noticed me.
- Implementarán acciones que impulsen las cadenas productivas de pesca, acuicultura, agroindustria y forestal
- Se asumieron acuerdos en el marco de los compromisos del 12° GORE Ejecutivo
- Viceministro Salardi entregó al alcalde provincial de Putumayo el expediente técnico aprobado para la construcción del mercado municipal
En el marco de la reunión para el cumplimiento de los compromisos derivados de la 12° del GORE Ejecutivo, el viceministro de Mype e Industria, José Salardi, señaló que el gobierno, a través del Ministerio de la Producción (Produce), impulsará el desarrollo de las cadenas productivas de pesca, acuicultura, agroindustria y forestal en Loreto, a través de un trabajo articulado con las autoridades regionales.
En ese sentido, indicó que la reunión de los equipos técnicos de su sector y del gobierno regional, ha dado como resultado una serie de acuerdos que contribuirán para que Loreto se convierta en una región productiva en base a sus potencialidades. "Hemos identificado que estamos muy alineados en muchas intervenciones, incluso en aquellas que ya tenemos en camino", destacó.
Al respecto, Salardi precisó que al cierre del primer semestre estarán implementados al 100 % el CITE Forestal y el CITE Productivo Maynas. "Es una inversión de 22 millones de soles que ha realizado Produce a través del ITP. Con lo cual se ha puesto en valor estas infraestructuras importantes, para poder dar todo apoyo y soporte a las cadenas productivas de pesca, acuicultura y agroindustrias".
Manifestó que para el presente año proyectan prestar un mínimo de 1200 servicios de innovación y transferencia tecnológica, que ayudará a fortalecer las capacidades e innovar a las diferentes industrias de esta región.
Asimismo, informó que otros de los compromisos es la pronta apertura del Centro de Desarrollo Empresarial del programa “Tu Empresa”, para promover la formalización de 400 nuevas unidades de negocio.
De otro lado, Salardi indicó que el sector espera cerrar el año inaugurando el Gran Mercado de Belén. "Se está avanzando a un nivel importante. El proyecto está a más de 50% de ejecución y en el presupuesto de este año se han incluido 50 millones de soles para su culminación", apuntó.
Acciones en pesca y acuicultura
De otro lado, el viceministro Salardi informó que, a través del FONDEPES, Produce iniciará la construcción del primer desembarcadero pesquero artesanal de la Amazonia “La Punchana”, para lo cual se ha destinado una inversión de hasta S/ 22 000 000.
Asimismo, este fondo realizará un proyecto piloto para la implementación de aislamiento térmico en embarcaciones pesqueras artesanales para el adecuado transporte de los productos hidrobiológicos. "Con esta actividad, se espera incrementar los fondos para créditos destinados a los pescadores artesanales y acuicultores de la región hasta por un valor de S/ 250 000", destacó.
Otro de los acuerdos es la implementación de mejoras en los servicios del Centro Acuícola Nuevo Horizonte, por un valor de hasta S/ 14 000 000, con ello se mejorarán los servicios de producción y distribución de alevinos para la ampliación de la frontera acuícola, así como la capacitación operativa especializada a los productores de la Región.
Mercado de Putumayo
Más tarde, el viceministro Salardi hizo entrega oficial al alcalde provincial de Putumayo, Humberto Fuentes, del expediente técnico aprobado para la ejecución del proyecto "Mejoramiento del Mercado Municipal de la Ciudad de San Antonio del Estrecho".
Esta importante acción del gobierno en una ciudad de frontera con Colombia, cuenta con una inversión de más de 4 millones de soles y beneficiará a más de 3000 habitantes.
Las obras se realizarán en un terreno de 1410 m2, donde se implementarán 40 puestos de comercio, con una moderna infraestructura e innovaciones que garantizarán la alta calidad de los productos.
The superficial markings of the highlighter, which are somewhat difficult to see in visible light, are clearly visible. Due to the shallow penetration of ultraviolet light, however, highlighter ink itself was largely obscured by almost every implement tested.
Baghdad, 07 March 2018 – Under the patronage of H.E. Prime Minister of Iraq, Dr. Hayder Al-Abadi , today in Baghdad a high level conference on implementation of Iraq National Action Plan on United Nations Security Council Resolution 1325 on women, peace and security in Iraq, was held.
In 2012-2014 the Iraqi Cross Sector Task Force (CSTF) developed the Iraqi National Action Plan (NAP) for implementation of the United Nations Security Council Resolution 1325. The NAP 1325 is a crucial tool for improving the status of women’s rights in Iraq. Composed of ministries, institutions and civil society, the CSTF has been the driving mechanism for implementing, monitoring, and reporting of this NAP.
At today’s conference, the Government of Iraq and CSTF took the opportunity to mark the International Women’s Day, 8th of March, by sharing the preliminary outcomes, lessons learned and conclusions summarized during the on-going process of developing of the draft national report on the implementation of the first NAP 1325, which will be presented to the United Nations Security Council later during 2018.
At the opening session of the conference, participants were greeted by the Prime Minister of Iraq, Dr. Hayder Al Abadi, Secretary General of the Council of Ministers and Co-Chair of the CSTF 1325, Dr. Mahdi Al Alaq, Chairperson of the National Committee for the Advancement of Iraqi Women and Chair of the Coordination Committee of CSTF 1325, Dr. Thikra Alloush, Chair of the High Council of Women of the Kurdistan Region and Co-Chair of CSTF 1325, Ms. Pakshan Zangana and by the Director General of the Iraqi Women Empowerment Department of the Council of Ministers, Dr. Ibtisam Aziz.
Representatives of the international community expressed their commitment to support women’s rights and their participation in the process of peace building in Iraq as well as in the upcoming phase of the development of the second NAP. On behalf of the International community the conference was addressed by the Special Representative of the United Nations Secretary-General for Iraq, Mr. Jan Kubiš, British Ambassador to Iraq, Jon Wilks, Charge d’Affairs of the Embassy of the Kingdom of the Netherlands, Marielle Geraedts, and by the Country Director of UN Women, Ms. Dina Zorba.
Photos by UNAMI PIO.
USAID stands with the Ukrainian people during wartime. All of our more than 40 development activities continue to operate, thanks to the brave and determined work of our network of implementing partners. Ambassador Brink met with a group of USAID implementing partners in Kyiv, thanking them for their continued work on the ground to support Ukraine and the Ukrainian people. USAID will continue to support Ukraine as it resists Russia’s aggression and prepares for a successful postwar recovery.