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This MRI scan shows a knee joint with cartilage covering the articulating joint surfaces to help the bones slide smoothly.
Cartilage responds slowly to changes in joint loading because it does not have any blood vessels, lymphatic system or nerves to feed and grow tissue, so nutrients are absorbed slowly.
Everyday loading of our skeleton is important to keep cartilage healthy because the motion and loading of the joint are needed to get nutrients into the cartilage, but little is known about cartilage in bedridden people on Earth.
To find out more, the Institute of Biomechanics and Orthopaedics of the German Sport University Cologne in Germany is studying astronauts.
As astronauts float in space for up to six months their legs are hardly used in weightlessness. The researchers are analysing biomarkers in up to 10 astronauts before and after flight to chart cartilage metabolism, thickness, volume and water content in knee joints.
This is the first time such a study is being done on healthy people. As cartilage responds so slowly, a similar study with healthy individuals on Earth would require that they do not move for many months, which is impossible.
The goal is to learn more about how the knee cartilage of the astronauts suffers from their trip into space. From here, researchers are hoping to understand the role of mechanical loading for cartilage health and the development of osteoarthritis.
Credit: ESA
Problems with resin on placemat two. Try to peal it off (works on smaller pieces of polymer) but fail.
This photo shot with my 1960's vintage Zenza Bronica S2A on Ilford film. Photo taken at Fish Lake in the mountains above Whitehorse, Southern Yukon.
Unfortunately, unbenownst to me, the old Bronica camera was suffering from a shutter problem. I got two perfect photos from the roll of 12 then each succeeding image had more and more of the frame cut off at the top. This image is the last of the useable frames, but it is one of only four that are. Every other image was ruined. The following roll was even worse, and then the camera locked up completely.
If any one out there has experience with this sort of issue on the S2/S2A, perhaps you could offer some suggestions in the comments, below? It really is a shame because, as you can see, this camera is capable of taking some striking images, and other than the shutter issue, it's a beautiful unit in mint condition.
The train pulls ahead and comes to a stop, the conductor is walking back to check a problem (air brakes?) The crew standing by is the bridge repair crew finished their project and packing up to leave town.
Haven't been posting much lately...A website and G+ with a dash of Tumblr have been keeping me busy...and life.
The one problem with spotting down here is that the tourists flock down here and make far-back nearside shots really rather difficult - such as in this case. A lack of room to back out means that the photos come out horribly glared, too, so I'm forced to put up with whatever I can get over style and substance. Prepare for some dodgily-framed shots!
I've ran out of interesting descriptors again - seen here coming rather unexpectedly up the High Street, Stagecoach Oxford Tube's 50432, a 2020 Volvo B11RET Plaxton Panorama, heads out for another run on the Tube to London Victoria coach station.
January 4, 2019
Minneapolis, Minnesota
A few weeks ago Julia and I took an intro to bouldering class at Minneapolis Bouldering Project and loved it. Our 2019 goals include both working on our fitness and trying new activities/fostering new hobbies, so after work today we joined the bouldering gym.
Bouldering is a form of rock climbing without using ropes or harnesses. It was originally developed as a way for rock climbers to practice more complex climbing moves at a safe distance from the ground - typically bouldering gyms' walls aren't more than 20 feet tall and have cushioned floors, in case of falls. Today, bouldering has become a sport in itself.
The different color coded routes on a wall in a bouldering gym are called problems. From the easiest, yellow, to the hardest, white, the problems are designed to not only test your physical ability, but also function as a puzzle for your mind as well.
I tried to ignore him and talk to the lord
Pray for him, cause some fools just love to perform
You know the type loud as a motor bike
But wouldn't bust a grape in a fruit fight
The only thing that's gonna happen is i'mma get to clapping
He and his boys gon' be yapping to the captain
And there I go trapped in the kit kat again
Back through the system with the riff raff again
Fiends on the floor scratching again
Paparazzi's with they cameras snapping them
D.A. tried to give the nigga the shaft again
Half-a-mil for bail cause I'm African
All because this fool was harrassin them
Trying to play the boy like hes saccharin
But ain't nothing sweet 'bout how I hold my gun
I got 99 problems but being a bitch ain't one
Hit Men
photo: godzilla7
I will accept my Nobel Prize with grace and humility for solving this age old problem. Thank you all :-)
Spot Signs of Foundation Problems in Plano TX t.co/8tXRvXVqmn t.co/cTpcJiym59 (via Twitter twitter.com/StratumFR/status/702738803291779072)
ODC: WHO AM I
Among other things, I am a problem solver. We got a package of these puzzles; the kids and I spent a fair amount of time testing our patience and determination... proving to ourselves that we are able to solve these problems. Eventually... problem solved!!!
Well, my friends, I am back, I had some little problems, and my computer crashed, now I am with other computer and will post some cool stuff, I have made another moc as well but I wanted to show my current project, its going to be huge and I am going t focus on it! Hope you like it! suggestions are welcome! If you are curious about something just ask it!
Lawrence
The consequences of the problems that arose with 45231's wheel-flats discovered on Good Friday, 2 April 2021 have almost concluded in south Wales as today (16 April 2021) the Black 5 was taken away by low-loader from Port Talbot 'Up' Sidings for rectification. For those that know nothing about the movement from where the failure was declared, Llandeilo and the aforementioned Port Talbot 'Up' Sidings, on 13 April two EE Type 3s, D6817/D6851 worked light engine from Crewe to Llandeilo. From there they worked a slow moving rescue to get 45231 complete with a wheel-skate on the tender's leading front axle to a suitable location to load the locomotive and tender onto low-loaders, Port Talbot 'Up' Sidings. Once the removal of 45231 was complete the two Type 3s led the support coach as 5Z37, the 13.54 Port Talbot 'Up' Sidings to Crewe. The working is seen passing through Pyle station and about to get stuck in to Stormy bank, I doubt if speed was reduced by the weight of the load!
D6817 was new in March 1963 and allocated to Tinsley, being renumbered 37117 and then 37521; D6851 is a little younger having been commissioned in July 1963 at Canton, renumbered 37151 and later 37667. They both looked superb in BR Green with small warning panels, about six photographers gathered on the station to witness the event.
Sam Robson, aka "Robbie" (1/6 Dark Zone Agent) is pondering the best way to protect his client while on a ski trip in Vancouver.
Not to worry, his coat and hat are beside him on the bench.
I’d been having problems through school and now college , teased for my young , girlish looks , my mother means well , but I get very tetchy about my long hair , she says I should get it cut , then I’d look more like a boy , true but then I look even younger , so I wea it long It had been a bad week Friday came and I admit I was miserable “I was having a chat with Barbara “ she’s mums old school friend , we get on well , I think she knows I have a bit of a crush on her. “She suggested tomorrow you cycle over and have lunch , you’ll enjoy the ride and she’d love to see you “ I had a strange feeling about it , but agreed So early Saturday morning I set off , it was ok , only about thirty miles , but half way there it clouded over and the heaven opened , I got absolutely soaked through , and muddy too Arriving at Barbara’s she opens the front door. “Oh sweet heart look at you , quick get out of those wet clothes ,I’ll run you a bath” So it was i had a lovely hot bath , she insisted on washing my hair too ! Your clothes are all wet and so dirty , they’ll need washing , your about the same size as Jennifer , her daughter I think one of her dresses will fit for now “ she suggests in a calm , matter of fact , way “Oh no , I can’t wear a dress I protest , although Jennifer’s kind of sexy , wearing her dress is a bit over the top “There must be some jeans “ I ask “No , you know Jennifer is very girlie , she hates jeans “ she reminds me , arguing is futile So I end up wearing a dress and , yes , panties too , then just to add insult to injury she blow dries my hair and uses curling tongues too , then even adds a little foundation and lipstick “There now no one will be any the wiser , I must say you look amazing , oh Sam take a look “ she leads me to the full length mirror , I can’t believe my eyes , I’m a girl , a very pretty girl , walking around in a dress feels so fabulous it swishes and sways feels so cool on my legs , she tried to get me into high heels l but that was a step too far , but the dress and panties are divinely lovely I feel so relaxed and at one with my feminine side too , even Barbara commented how much happier and relaxed I’d become too
My sister retired today. She is two years and three months younger than me; I've still got 49½ working days to go ...not that I'm counting or anything. And they say it's a man's world. Fwuh!
I can't bloody-well wait. Since leaving the buses in June 1990 I've done stupid, blue collar, low-paid jobs like this, surrounded during the last ten years by immigrants from eastern Europe (with a smattering from Portugal and Brazil) because our native dossers are unwilling to do such work. The unwillingness I completely understand. I do it most unwillingly myself: but then, the same applies to every job I've ever done. I've loathed every single minute of working life, but I've done it, and I feel there has been a kind of resigned, beetle-like heroism in the relentless getting up and going in every day. I've never been unemployed. I've worked because I've had to, the alternative being to live under a railway bridge and eat scraps from litter bins. We are all "free" to do that.
Come to think of it, I hated school too. School and work have been the total of my life so far. Of retirement I cannot yet give an opinion, but I've looked forward to it as a far-off, blessed deliverance from suffering since about the third day of my working life, that is since February 1966.
Perhaps I will return to this subject during the mercifully decreasing number of days that stand between me and a pension. This was actually taken back in my "lost" digital years, in November 2007. Note the food industry hairnet. They were white in those days. Apparently the colour is important, and has been changed twice since. We now use blue; I've no idea why. Those wifty little "bump guard" jockey cap things were replaced by proper hard hats, latterly with ear defenders. They make me look ever so butch. All I need now is a pair of rigger boots. This was "my" reach truck, then nearing the end of its "rental aggreement". It was replaced by another not long afterwards. I preferred the older one. About six months ago one of my colleagues, told to clean the newer truck (we must have been trying to pull the wool over the eyes of some auditors, or a deputation of big knobs from Head Office), thought that the easiest way to accomplish this would be to take it outside and hose it down. In this he was doubtlessly correct; unfortunately it blew all the truck's electrical circuits. The estimate for repair was £3,000. We parked the truck in a corner and managed to keep the matter from our boss until about a fortnight ago when ...blimey! ...he actually descended from "upstairs" and made an appearance on the shop floor. By this time the person responsible had been sacked for a series of unrelated misdemeanors, mostly involving collisions between his truck and various parts of the building.
Lothian 656 having a few issues with the rear rollerblind with it only showing what blind this is. 30th June 2015.
This must perfectly express the sentiments of anyone working in anything remotely like customer service. I found this sign and hung it in the office of my workplace, but first I photographed it to share with anyone who might like it as much as I do.
Motorists wait at the road crossing outside Civic as 3642 hurries through with a shuttle service to Cockle Creek.
A lavoro, quando il tempo non passa mai e le pressioni di Dolce e Gabbana e Co. aumentano, l’unica soluzione è aspettare con trepidazione questa canzone
www.youtube.com/watch?v=L1R--qzltJY&feature=related
e in un secondo ci uniamo con spensieratezza per cinguettare tutte insieme, formando trenini da ballo!!! AHAHHAHHA!!! :D
Ascoltare per credere!
Sono stanca e arrabbiata
E sto cercando di importarmene un po’ meno di tutto
e quando vado su google, mi deprimo soltanto
Mi hanno insegnato a schivare questi problemi
mi era stato detto: non ti preoccupare, non ci sono dubbi
C’è sempre qualcosa per cui piangere
Quando sei bloccato in una folla inferocita
Loro non pensano a quello che dicono
prima di aprire la bocca, tu devi:
Impacchettare i tuoi problemi nel tuo vecchio borsone
E seppellirli sotto il mare
Non mi interessa ciò che la gente può dire
Ciò che la gente può dire su di me
Impacchettare i tuoi problemi
e riprenderti il tuo vecchio sorriso
Non ti preoccupare della cavalleria
Non mi interessa quello che dicono gli impiccioni
Perchè loro sussurrano a voce troppo alta per me.
......
cinguetta cinguetta...
si, si..
Artista: Eliza Doolittle
Titolo: Pack Up
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The carburettor just needs a bit of fine tuning sir...
How many unfinished restoration project adverts do you see that in ?
( In other words, i'm pig sick of trying to sort out that niggling problem ! )
After almost a year of worrying medical problems which are ongoing for Brian it was so good to at last get out with the camera and just see what was around.
We were more than pleased to find these tiny birds in a ‘hot spot’ that we know and where Brian can sit and I just stand and hope they turn up.
When they do of course they are never still making photography a real challenge but on this late October day we were happy just to be out and for me to have a few clicks.
A light-hearted sign observed on the exterior of The Swan Hotel, public house on Corporation Street, St Helens, Merseyside.
Format: Still image
Abstract: Homemaker is helping a mother who has home management and child care problems.
Extent: 1 photoprint.
NLM Unique ID: 101448556
NLM Image ID: A029680
Permanent Link: resource.nlm.nih.gov/101448556
My nephew Marian (4) has a problem. The beer cap is too tough for him. You can guess from his expression how hard is he pushing to open the bottle of Budweiser. But since he is rather stubborn he finally made it. Yes, "if you want you can". Taken with Zuiko OM 50/1,8, aperture either 1,8 or 2, ambient light, cropped in photoshop.
If you are in bed, make an appointment for the hospital burns unit to see you soon.
It might be a tradition - but it is not a good one.
1951
On Saturday the L train was suspended for a bit because of a rail problem north of Bedford avenue. Subway issues can bring "The City That Never Sleeps" to a screeching halt.
The American Queen docked in Hannibal, Missouri on Sunday due to problems with the locks in St. Louis, Missouri. The steamboat is scheduled to depart today. When I heard this majestic steamboat was there I jumped in the car and drove the 20 minutes to Hannibal. She didn't disappoint. I had seen the Delta Queen and the Mississippi Queen in the past but never the American Queen.
The American Queen was built in 1995, has 6 decks, 222 staterooms, is 418 feet long and 89 feet wide. She is said to be the largest river steamboat ever built. A true beauty she is.
Out of curiosity I looked up the fate of the Delta Queen and the Mississippi Queen. The Delta Queen is currently docked in Chattanooga, Tennessee and is being used as a hotel. Sadly, the Mississippi Queen was scrapped in 2011.
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