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Detail of the Golden Window, one of the final pair of nave windows representing the soul's final journey into Heaven. This window was designed by Lawrence Lee and represents the Heavenly City, studded with gemstones and with a large figure of Archangel Michael at the centre. At the base a shadowy Christ-like figure appears to welcome us.
Coventry's Cathedral is a unique synthesis of old a new, born of wartime suffering and forged in the spirit of postwar optimism, famous for it's history and for being the most radically modern of Anglican cathedrals. Two cathedral's stand side by side, the ruins of the medieval building, destroyed by incendiary bombs in 1940 and the bold new building designed by Basil Spence and opened in 1962.
It is a common misconception that Coventry lost it's first cathedral in the wartime blitz, but the bombs actually destroyed it's second; the original medieval cathedral was the monastic St Mary's, a large cruciform building believed to have been similar in appearance to Lichfield Cathedral (whose diocese it shared). Tragically it became the only English cathedral to be destroyed during the Reformation, after which it was quickly quarried away, leaving only scant fragments, but enough evidence survives to indicate it's rich decoration (some pieces were displayed nearby in the Priory Visitors Centre, sadly since closed). Foundations of it's apse were found during the building of the new cathedral in the 1950s, thus technically three cathedrals share the same site.
The mainly 15th century St Michael's parish church became the seat of the new diocese of Coventry in 1918, and being one of the largest parish churches in the country it was upgraded to cathedral status without structural changes (unlike most 'parish church' cathedrals created in the early 20th century). It lasted in this role a mere 22 years before being burned to the ground in the 1940 Coventry Blitz, leaving only the outer walls and the magnificent tapering tower and spire (the extensive arcades and clerestoreys collapsed completely in the fire, precipitated by the roof reinforcement girders, installed in the Victorian restoration, that buckled in the intense heat).
The determination to rebuild the cathedral in some form was born on the day of the bombing, however it wasn't until the mid 1950s that a competition was held and Sir Basil Spence's design was chosen. Spence had been so moved by experiencing the ruined church he resolved to retain it entirely to serve as a forecourt to the new church. He envisaged the two being linked by a glass screen wall so that the old church would be visible from within the new.
Built between 1957-62 at a right-angle to the ruins, the new cathedral attracted controversy for it's modern form, and yet some modernists argued that it didn't go far enough, after all there are echoes of the Gothic style in the great stone-mullioned windows of the nave and the net vaulting (actually a free-standing canopy) within. What is exceptional is the way art has been used as such an integral part of the building, a watershed moment, revolutionising the concept of religious art in Britain.
Spence employed some of the biggest names in contemporary art to contribute their vision to his; the exterior is adorned with Jacob Epstein's triumphant bronze figures of Archangel Michael (patron of the cathedral) vanquishing the Devil. At the entrance is the remarkable glass wall, engraved by John Hutton with strikingly stylised figures of saints and angels, and allowing the interior of the new to communicate with the ruin. Inside, the great tapestry of Christ in majesty surrounded by the evangelistic creatures, draws the eye beyond the high altar; it was designed by Graham Sutherland and was the largest tapestry ever made.
However one of the greatest features of Coventry is it's wealth of modern stained glass, something Spence resolved to include having witnessed the bleakness of Chartres Cathedral in wartime, all it's stained glass having been removed. The first window encountered on entering is the enormous 'chess-board' baptistry window filled with stunning abstract glass by John Piper & Patrick Reyntiens, a symphony of glowing colour. The staggered nave walls are illuminated by ten narrow floor to ceiling windows filled with semi-abstract symbolic designs arranged in pairs of dominant colours (green, red, multi-coloured, purple/blue and gold) representing the souls journey to maturity, and revealed gradually as one approaches the altar. This amazing project was the work of three designers lead by master glass artist Lawrence Lee of the Royal College of Art along with Keith New and Geoffrey Clarke (each artist designed three of the windows individually and all collaborated on the last).
The cathedral still dazzles the visitor with the boldness of it's vision, but alas, half a century on, it was not a vision to be repeated and few of the churches and cathedrals built since can claim to have embraced the synthesis of art and architecture in the way Basil Spence did at Coventry.
The cathedral is generally open to visitors most days. For more see below:-
The Maserati Barchetta is a mid-engine racing car, like the 350 and 450S, that was designed by Carlo Gaino of the "Synthesis Design", an Italian design house.
The Barchetta was designed and developed for the one-make racing series Grantrofeo Barchetta which was held 1992 and 1993 throughout Italy and Europe. It featured sixteen races in total, most of them in Italy. The Barchetta had a backbone chassis made of aluminium which was unusual for a Maserati automobile for a time considering that the cars offered by Maserati had a steel unibody construction. It had a Formula 1 suspension geometry and body panels made of carbon fibre which resulted in a total weight of 775 kg (1,709 lb). The Barchetta was one of the last Maserati models built under De Tomaso ownership.
16 examples of the racing model were produced by hand at the De Tomaso factory in Modena, plus two prototypes (one racing-corsa, one street-stradale model). It featured a mid-mounted Maserati AM501 V6 engine displacing 1,996 cc and was shared with the local 2.0 L engine offered in the Italian market on the Biturbo and the Ghibli. The engine had a peak power output of 319 PS (235 kW; 315 hp) at 7,250 rpm. The engine was mated to a 6-speed manual transmission manufactured by ZF Friedrichshafen and having straight cut gears. These modifications allowed the car to attain a top speed of 290 km/h (180 mph). Having a true open top design, driver protection was only provided by a small air deflector.
The central-frame concept was carried over in the De Tomaso Guarà, but the frame was around 130 mm (5.1 in) longer because it was fitted with a larger V8 engine.
This was thought as a way to inject much needed excitement and enthusiasm for Maserati that saw its reputation badly ruined by years of exciting but maintenance sensitive products,[ eventually culminating in Maserati's withdrawal from the North American market at this time.
Westerbork, Drenthe province of Netherlands.
It is now a site of a powerful radio telescope (en.wikipedia.org/wiki/Westerbork_Synthesis_Radio_Telescope).
In WWII a transit concentration camp lied on this site
"In synthesis, the Lenten journey, in which we are invited to contemplate the Mystery of the Cross, is meant to reproduce within us “the pattern of his death” (Ph 3: 10), so as to effect a deep conversion in our lives; that we may be transformed by the action of the Holy Spirit, like St. Paul on the road to Damascus; that we may firmly orient our existence according to the will of God; that we may be freed of our egoism, overcoming the instinct to dominate others and opening us to the love of Christ. The Lenten period is a favorable time to recognize our weakness and to accept, through a sincere inventory of our life, the renewing Grace of the Sacrament of Penance, and walk resolutely towards Christ."
– Pope Benedict XVI.
Stained glass of a Rosary and Crucifix from the Dominican friars' chapel in Caleruega, Spain.
Coventry's Cathedral is a unique synthesis of old a new, born of wartime suffering and forged in the spirit of postwar optimism, famous for it's history and for being the most radically modern of Anglican cathedrals. Two cathedral's stand side by side, the ruins of the medieval building, destroyed by incendiary bombs in 1940 and the bold new building designed by Basil Spence and opened in 1962.
It is a common misconception that Coventry lost it's first cathedral in the wartime blitz, but the bombs actually destroyed it's second; the original medieval cathedral was the monastic St Mary's, a large cruciform building believed to have been similar in appearance to Lichfield Cathedral (whose diocese it shared). Tragically it became the only English cathedral to be destroyed during the Reformation, after which it was quickly quarried away, leaving only scant fragments, but enough evidence survives to indicate it's rich decoration (some pieces were displayed nearby in the Priory Visitors Centre, sadly since closed). Foundations of it's apse were found during the building of the new cathedral in the 1950s, thus technically three cathedrals share the same site.
The mainly 15th century St Michael's parish church became the seat of the new diocese of Coventry in 1918, and being one of the largest parish churches in the country it was upgraded to cathedral status without structural changes (unlike most 'parish church' cathedrals created in the early 20th century). It lasted in this role a mere 22 years before being burned to the ground in the 1940 Coventry Blitz, leaving only the outer walls and the magnificent tapering tower and spire (the extensive arcades and clerestoreys collapsed completely in the fire, precipitated by the roof reinforcement girders, installed in the Victorian restoration, that buckled in the intense heat).
The determination to rebuild the cathedral in some form was born on the day of the bombing, however it wasn't until the mid 1950s that a competition was held and Sir Basil Spence's design was chosen. Spence had been so moved by experiencing the ruined church he resolved to retain it entirely to serve as a forecourt to the new church. He envisaged the two being linked by a glass screen wall so that the old church would be visible from within the new.
Built between 1957-62 at a right-angle to the ruins, the new cathedral attracted controversy for it's modern form, and yet some modernists argued that it didn't go far enough, after all there are echoes of the Gothic style in the great stone-mullioned windows of the nave and the net vaulting (actually a free-standing canopy) within. What is exceptional is the way art has been used as such an integral part of the building, a watershed moment, revolutionising the concept of religious art in Britain.
Spence employed some of the biggest names in contemporary art to contribute their vision to his; the exterior is adorned with Jacob Epstein's triumphant bronze figures of Archangel Michael (patron of the cathedral) vanquishing the Devil. At the entrance is the remarkable glass wall, engraved by John Hutton with strikingly stylised figures of saints and angels, and allowing the interior of the new to communicate with the ruin. Inside, the great tapestry of Christ in majesty surrounded by the evangelistic creatures, draws the eye beyond the high altar; it was designed by Graham Sutherland and was the largest tapestry ever made.
However one of the greatest features of Coventry is it's wealth of modern stained glass, something Spence resolved to include having witnessed the bleakness of Chartres Cathedral in wartime, all it's stained glass having been removed. The first window encountered on entering is the enormous 'chess-board' baptistry window filled with stunning abstract glass by John Piper & Patrick Reyntiens, a symphony of glowing colour. The staggered nave walls are illuminated by ten narrow floor to ceiling windows filled with semi-abstract symbolic designs arranged in pairs of dominant colours (green, red, multi-coloured, purple/blue and gold) representing the souls journey to maturity, and revealed gradually as one approaches the altar. This amazing project was the work of three designers lead by master glass artist Lawrence Lee of the Royal College of Art along with Keith New and Geoffrey Clarke (each artist designed three of the windows individually and all collaborated on the last).
The cathedral still dazzles the visitor with the boldness of it's vision, but alas, half a century on, it was not a vision to be repeated and few of the churches and cathedrals built since can claim to have embraced the synthesis of art and architecture in the way Basil Spence did at Coventry.
The cathedral is generally open to visitors most days. For more see below:-
Testosterone
The chemical structure of testosterone.
A ball-and-stick model of testosterone.
Names
IUPAC name
17β-Hydroxyandrost-4-en-3-one
Systematic IUPAC name
(8R,9S,10R,13S,14S,17S)-17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Other names
Androst-4-en-17β-ol-3-one
Identifiers
CAS Number
58-22-0 ☑
3D model (JSmol)
Interactive image
ChEBI
CHEBI:17347 ☑
ChEMBL
ChEMBL386630 ☑
ChemSpider
5791 ☑
DrugBank
DB00624 ☑
ECHA InfoCard100.000.336
KEGG
D00075 ☑
PubChem CID
6013
UNII
3XMK78S47O ☑
InChI[show]
SMILES[show]
Properties
Chemical formula
C19H28O2
Molar mass288.431 g·mol−1
Melting point155 °C
Pharmacology
ATC code
G03BA03 (WHO)
License data
EU EMA: by INN
Routes of
administration
Transdermal (gel, cream, solution, patch), by mouth (as testosterone undecanoate), in the cheek, intranasal (gel), intramuscular injection (as esters), subcutaneous pellets
Pharmacokinetics:
Bioavailability
Oral: very low (due to extensive first pass metabolism)
Protein binding
97.0–99.5% (to SHBG and albumin)[1]
Metabolism
Liver (mainly reduction and conjugation)
Biological half-life
2–4 hours[citation needed]
Excretion
Urine (90%), feces (6%)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Testosterone is the primary male sex hormone and an anabolic steroid. In male humans, testosterone plays a key role in the development of male reproductive tissues such as testes and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.[2] In addition, testosterone is involved in health and well-being,[3] and the prevention of osteoporosis.[4] Insufficient levels of testosterone in men may lead to abnormalities including frailty and bone loss.
Testosterone is a steroid from the androstane class containing a keto and hydroxyl groups at the three and seventeen positions respectively. It is biosynthesized in several steps from cholesterol and is converted in the liver to inactive metabolites.[5] It exerts its action through binding to and activation of the androgen receptor.[5] In humans and most other vertebrates, testosterone is secreted primarily by the testicles of males and, to a lesser extent, the ovaries of females. On average, in adult males, levels of testosterone are about 7 to 8 times as great as in adult females.[6] As the metabolism of testosterone in males is more pronounced, the daily production is about 20 times greater in men.[7][8] Females are also more sensitive to the hormone.[9]
In addition to its role as a natural hormone, testosterone is used as a medication, for instance in the treatment of low testosterone levels in men and breast cancer in women.[10] Since testosterone levels decrease as men age, testosterone is sometimes used in older men to counteract this deficiency. It is also used illicitly to enhance physique and performance, for instance in athletes.
Contents
1Biological effects
1.1Before birth
1.2Early infancy
1.3Before puberty
1.4Pubertal
1.5Adult
1.6Aggression and criminality
1.7Brain
2Medical use
3Biological activity
3.1Steroid hormone activity
3.2Neurosteroid activity
4Biochemistry
4.1Biosynthesis
4.2Distribution
4.3Metabolism
4.4Levels
5Measurement
6History
7Other animals
8See also
9References
10Further reading
Biological effects[edit]
In general, androgens such as testosterone promote protein synthesis and thus growth of tissues with androgen receptors.[11] Testosterone can be described as having virilising and anabolic effects (though these categorical descriptions are somewhat arbitrary, as there is a great deal of mutual overlap between them).[12]
Anabolic effects include growth of muscle mass and strength, increased bone density and strength, and stimulation of linear growth and bone maturation.
Androgenic effects include maturation of the sex organs, particularly the penis and the formation of the scrotum in the fetus, and after birth (usually at puberty) a deepening of the voice, growth of facial hair (such as the beard) and axillary (underarm) hair. Many of these fall into the category of male secondary sex characteristics.
Testosterone effects can also be classified by the age of usual occurrence. For postnatal effects in both males and females, these are mostly dependent on the levels and duration of circulating free testosterone.
Before birth[edit]
Effects before birth are divided into two categories, classified in relation to the stages of development.
The first period occurs between 4 and 6 weeks of the gestation. Examples include genital virilisation such as midline fusion, phallic urethra, scrotal thinning and rugation, and phallic enlargement; although the role of testosterone is far smaller than that of dihydrotestosterone. There is also development of the prostate gland and seminal vesicles.
During the second trimester, androgen level is associated with sex formation.[13] This period affects the femininization or masculinization of the fetus and can be a better predictor of feminine or masculine behaviours such as sex typed behaviour than an adult's own levels. A mother's testosterone level during pregnancy is correlated with her daughter's sex-typical behavior as an adult, and the correlation is even stronger than with the daughter's own adult testosterone level.[14]
Early infancy[edit]
Early infancy androgen effects are the least understood. In the first weeks of life for male infants, testosterone levels rise. The levels remain in a pubertal range for a few months, but usually reach the barely detectable levels of childhood by 4–7 months of age.[15][16] The function of this rise in humans is unknown. It has been theorized that brain masculinization is occurring since no significant changes have been identified in other parts of the body.[17] The male brain is masculinized by the aromatization of testosterone into estrogen, which crosses the blood–brain barrier and enters the male brain, whereas female fetuses have α-fetoprotein, which binds the estrogen so that female brains are not affected.[18]
Before puberty[edit]
Before puberty effects of rising androgen levels occur in both boys and girls. These include adult-type body odor, increased oiliness of skin and hair, acne, pubarche (appearance of pubic hair), axillary hair (armpit hair), growth spurt, accelerated bone maturation, and facial hair.[19]
Pubertal[edit]
Pubertal effects begin to occur when androgen has been higher than normal adult female levels for months or years. In males, these are usual late pubertal effects, and occur in women after prolonged periods of heightened levels of free testosterone in the blood. The effects include:[19][20]
Growth of spermatogenic tissue in testicles, male fertility, penis or clitoris enlargement, increased libido and frequency of erection or clitoral engorgement occurs. Growth of jaw, brow, chin, and nose and remodeling of facial bone contours, in conjunction with human growth hormone occurs.[21] Completion of bone maturation and termination of growth. This occurs indirectly via estradiol metabolites and hence more gradually in men than women. Increased muscle strength and mass, shoulders become broader and rib cage expands, deepening of voice, growth of the Adam's apple. Enlargement of sebaceous glands. This might cause acne, subcutaneous fat in face decreases. Pubic hair extends to thighs and up toward umbilicus, development of facial hair (sideburns, beard, moustache), loss of scalp hair (androgenetic alopecia), increase in chest hair, periareolar hair, perianal hair, leg hair, armpit hair.
Adult[edit]
Testosterone is necessary for normal sperm development. It activates genes in Sertoli cells, which promote differentiation of spermatogonia. It regulates acute HPA (hypothalamic–pituitary–adrenal axis) response under dominance challenge.[22] Androgen including testosterone enhances muscle growth. Testosterone also regulates the population of thromboxane A2 receptors on megakaryocytes and platelets and hence platelet aggregation in humans.[23][24]
Adult testosterone effects are more clearly demonstrable in males than in females, but are likely important to both sexes. Some of these effects may decline as testosterone levels might decrease in the later decades of adult life.[25]
Health risks[edit]
Testosterone does not appear to increase the risk of developing prostate cancer. In people who have undergone testosterone deprivation therapy, testosterone increases beyond the castrate level have been shown to increase the rate of spread of an existing prostate cancer.[26][27][28]
Conflicting results have been obtained concerning the importance of testosterone in maintaining cardiovascular health.[29][30] Nevertheless, maintaining normal testosterone levels in elderly men has been shown to improve many parameters that are thought to reduce cardiovascular disease risk, such as increased lean body mass, decreased visceral fat mass, decreased total cholesterol, and glycemic control.[31]
High androgen levels are associated with menstrual cycle irregularities in both clinical populations and healthy women.[32]
Sexual arousal[edit]
See also: Hormones and sexual arousal
When testosterone and endorphins in ejaculated semen meet the cervical wall after sexual intercourse, females receive a spike in testosterone, endorphin, and oxytocin levels, and males after orgasm during copulation experience an increase in endorphins and a marked increase in oxytocin levels. This adds to the hospitable physiological environment in the female internal reproductive tract for conceiving, and later for nurturing the conceptus in the pre-embryonic stages, and stimulates feelings of love, desire, and paternal care in the male (this is the only time male oxytocin levels rival a female's).[citation needed]
Testosterone levels follow a nyctohemeral rhythm that peaks early each day, regardless of sexual activity.[33]
There are positive correlations between positive orgasm experience in women and testosterone levels where relaxation was a key perception of the experience. There is no correlation between testosterone and men's perceptions of their orgasm experience, and also no correlation between higher testosterone levels and greater sexual assertiveness in either sex.[34]
Sexual arousal and masturbation in women produce small increases in testosterone concentrations.[35] The plasma levels of various steroids significantly increase after masturbation in men and the testosterone levels correlate to those levels.[36]
Mammalian studies[edit]
Studies conducted in rats have indicated that their degree of sexual arousal is sensitive to reductions in testosterone. When testosterone-deprived rats were given medium levels of testosterone, their sexual behaviors (copulation, partner preference, etc.) resumed, but not when given low amounts of the same hormone. Therefore, these mammals may provide a model for studying clinical populations among humans suffering from sexual arousal deficits such as hypoactive sexual desire disorder.[37]
In every mammalian species examined demonstrated a marked increase in a male's testosterone level upon encountering a novel female. The reflexive testosterone increases in male mice is related to the male's initial level of sexual arousal.[38]
In non-human primates, it may be that testosterone in puberty stimulates sexual arousal, which allows the primate to increasingly seek out sexual experiences with females and thus creates a sexual preference for females.[39] Some research has also indicated that if testosterone is eliminated in an adult male human or other adult male primate's system, its sexual motivation decreases, but there is no corresponding decrease in ability to engage in sexual activity (mounting, ejaculating, etc.).[39]
In accordance with sperm competition theory, testosterone levels are shown to increase as a response to previously neutral stimuli when conditioned to become sexual in male rats.[40] This reaction engages penile reflexes (such as erection and ejaculation) that aid in sperm competition when more than one male is present in mating encounters, allowing for more production of successful sperm and a higher chance of reproduction.
Males[edit]
In men, higher levels of testosterone are associated with periods of sexual activity.[41][42]
Men who watch a sexually explicit movie have an average increase of 35% in testosterone, peaking at 60–90 minutes after the end of the film, but no increase is seen in men who watch sexually neutral films.[43] Men who watch sexually explicit films also report increased motivation, competitiveness, and decreased exhaustion.[44] A link has also been found between relaxation following sexual arousal and testosterone levels.[45]
Men's levels of testosterone, a hormone known to affect men's mating behaviour, changes depending on whether they are exposed to an ovulating or nonovulating woman's body odour. Men who are exposed to scents of ovulating women maintained a stable testosterone level that was higher than the testosterone level of men exposed to nonovulation cues. Testosterone levels and sexual arousal in men are heavily aware of hormone cycles in females.[46] This may be linked to the ovulatory shift hypothesis,[47] where males are adapted to respond to the ovulation cycles of females by sensing when they are most fertile and whereby females look for preferred male mates when they are the most fertile; both actions may be driven by hormones.
Females[edit]
Androgens may modulate the physiology of vaginal tissue and contribute to female genital sexual arousal.[48] Women's level of testosterone is higher when measured pre-intercourse vs pre-cuddling, as well as post-intercourse vs post-cuddling.[49] There is a time lag effect when testosterone is administered, on genital arousal in women. In addition, a continuous increase in vaginal sexual arousal may result in higher genital sensations and sexual appetitive behaviors.[50]
When females have a higher baseline level of testosterone, they have higher increases in sexual arousal levels but smaller increases in testosterone, indicating a ceiling effect on testosterone levels in females. Sexual thoughts also change the level of testosterone but not level of cortisol in the female body, and hormonal contraceptives may affect the variation in testosterone response to sexual thoughts.[51]
Testosterone may prove to be an effective treatment in female sexual arousal disorders,[52] and is available as a dermal patch. There is no FDA approved androgen preparation for the treatment of androgen insufficiency; however, it has been used off-label to treat low libido and sexual dysfunction in older women. Testosterone may be a treatment for postmenopausal women as long as they are effectively estrogenized.[52]
Romantic relationships[edit]
Falling in love decreases men's testosterone levels while increasing women's testosterone levels. There has been speculation that these changes in testosterone result in the temporary reduction of differences in behavior between the sexes.[53] However, it is suggested that after the "honeymoon phase" ends—about four years into a relationship—this change in testosterone levels is no longer apparent.[53] Men who produce less testosterone are more likely to be in a relationship[54] or married,[55] and men who produce more testosterone are more likely to divorce;[55] however, causality cannot be determined in this correlation. Marriage or commitment could cause a decrease in testosterone levels.[56] Single men who have not had relationship experience have lower testosterone levels than single men with experience. It is suggested that these single men with prior experience are in a more competitive state than their non-experienced counterparts.[57] Married men who engage in bond-maintenance activities such as spending the day with their spouse/and or child have no different testosterone levels compared to times when they do not engage in such activities. Collectively, these results suggest that the presence of competitive activities rather than bond-maintenance activities are more relevant to changes in testosterone levels.[58]
Men who produce more testosterone are more likely to engage in extramarital sex.[55] Testosterone levels do not rely on physical presence of a partner; testosterone levels of men engaging in same-city and long-distance relationships are similar.[54] Physical presence may be required for women who are in relationships for the testosterone–partner interaction, where same-city partnered women have lower testosterone levels than long-distance partnered women.[59]
Fatherhood[edit]
Fatherhood decreases testosterone levels in men, suggesting that the emotions and behavior tied to decreased testosterone promote paternal care. In humans and other species that utilize allomaternal care, paternal investment in offspring is beneficial to said offspring's survival because it allows the parental dyad to raise multiple children simultaneously. This increases the reproductive fitness of the parents, because their offspring are more likely to survive and reproduce. Paternal care increases offspring survival due to increased access to higher quality food and reduced physical and immunological threats.[60] This is particularly beneficial for humans since offspring are dependent on parents for extended periods of time and mothers have relatively short inter-birth intervals.[61] While extent of paternal care varies between cultures, higher investment in direct child care has been seen to be correlated with lower average testosterone levels as well as temporary fluctuations.[62] For instance, fluctuation in testosterone levels when a child is in distress has been found to be indicative of fathering styles. If a father's testosterone levels decrease in response to hearing their baby cry, it is an indication of empathizing with the baby. This is associated with increased nurturing behavior and better outcomes for the infant.[63]
Motivation[edit]
Testosterone levels play a major role in risk-taking during financial decisions.[64][65]
Aggression and criminality [edit]
See also: Aggression § Testosterone, and Biosocial criminology
Most studies support a link between adult criminality and testosterone, although the relationship is modest if examined separately for each sex. Nearly all studies of juvenile delinquency and testosterone are not significant. Most studies have also found testosterone to be associated with behaviors or personality traits linked with criminality such as antisocial behavior and alcoholism. Many studies have also been done on the relationship between more general aggressive behavior/feelings and testosterone. About half the studies have found a relationship and about half no relationship.[66]
Testosterone is only one of many factors that influence aggression and the effects of previous experience and environmental stimuli have been found to correlate more strongly. A few studies indicate that the testosterone derivative estradiol (one form of estrogen) might play an important role in male aggression.[66][67][68][69] Studies have also found that testosterone facilitates aggression by modulating vasopressin receptors in the hypothalamus.[70]
The sexual hormone can encourage fair behavior. For the study, subjects took part in a behavioral experiment where the distribution of a real amount of money was decided. The rules allowed both fair and unfair offers. The negotiating partner could subsequently accept or decline the offer. The fairer the offer, the less probable a refusal by the negotiating partner. If no agreement was reached, neither party earned anything. Test subjects with an artificially enhanced testosterone level generally made better, fairer offers than those who received placebos, thus reducing the risk of a rejection of their offer to a minimum. Two later studies have empirically confirmed these results.[71][72][73] However men with high testosterone were significantly 27% less generous in an ultimatum game.[74] The Annual NY Academy of Sciences has also found anabolic steroid use which increase testosterone to be higher in teenagers, and this was associated with increased violence.[75] Studies have also found administered testosterone to increase verbal aggression and anger in some participants.[76]
Testosterone is significantly correlated with aggression and competitive behaviour and is directly facilitated by the latter. There are two theories on the role of testosterone in aggression and competition.[77] The first one is the challenge hypothesis which states that testosterone would increase during puberty thus facilitating reproductive and competitive behaviour which would include aggression.[77] Thus it is the challenge of competition among males of the species that facilitates aggression and violence.[77] Studies conducted have found direct correlation between testosterone and dominance especially among the most violent criminals in prison who had the highest testosterone levels.[77] The same research also found fathers (those outside competitive environments) had the lowest testosterone levels compared to other males.[77]
The second theory is similar and is known as "evolutionary neuroandrogenic (ENA) theory of male aggression".[78][79] Testosterone and other androgens have evolved to masculinize a brain in order to be competitive even to the point of risking harm to the person and others. By doing so, individuals with masculinized brains as a result of pre-natal and adult life testosterone and androgens enhance their resource acquiring abilities in order to survive, attract and copulate with mates as much as possible.[78] The masculinization of the brain is not just mediated by testosterone levels at the adult stage, but also testosterone exposure in the womb as a fetus. Higher pre-natal testosterone indicated by a low digit ratio as well as adult testosterone levels increased risk of fouls or aggression among male players in a soccer game.[80] Studies have also found higher pre-natal testosterone or lower digit ratio to be correlated with higher aggression in males.[81][82][83][84][85]
The rise in testosterone levels during competition predicted aggression in males but not in females.[86] Subjects who interacted with hand guns and an experimental game showed rise in testosterone and aggression.[87] Natural selection might have evolved males to be more sensitive to competitive and status challenge situations and that the interacting roles of testosterone are the essential ingredient for aggressive behaviour in these situations.[88] Testosterone produces aggression by activating subcortical areas in the brain, which may also be inhibited or suppressed by social norms or familial situations while still manifesting in diverse intensities and ways through thoughts, anger, verbal aggression, competition, dominance and physical violence.[89] Testosterone mediates attraction to cruel and violent cues in men by promoting extended viewing of violent stimuli.[90] Testosterone specific structural brain characteristic can predict aggressive behaviour in individuals.[91]
Estradiol is known to correlate with aggression in male mice.[92] Moreover, the conversion of testosterone to estradiol regulates male aggression in sparrows during breeding season.[93] Rats who were given anabolic steroids that increase testosterone were also more physically aggressive to provocation as a result of "threat sensitivity".[94]
Brain[edit]
The brain is also affected by this sexual differentiation;[13] the enzyme aromatase converts testosterone into estradiol that is responsible for masculinization of the brain in male mice. In humans, masculinization of the fetal brain appears, by observation of gender preference in patients with congenital diseases of androgen formation or androgen receptor function, to be associated with functional androgen receptors.[95]
There are some differences between a male and female brain (possibly the result of different testosterone levels), one of them being size: the male human brain is, on average, larger.[96] Men were found to have a total myelinated fiber length of 176 000 km at the age of 20, whereas in women the total length was 149 000 km (approx. 15% less).[97]
No immediate short term effects on mood or behavior were found from the administration of supraphysiologic doses of testosterone for 10 weeks on 43 healthy men.[98] A correlation between testosterone and risk tolerance in career choice exists among women.[64][99]
Attention, memory, and spatial ability are key cognitive functions affected by testosterone in humans. Preliminary evidence suggests that low testosterone levels may be a risk factor for cognitive decline and possibly for dementia of the Alzheimer's type,[100][101][102][103] a key argument in life extension medicine for the use of testosterone in anti-aging therapies. Much of the literature, however, suggests a curvilinear or even quadratic relationship between spatial performance and circulating testosterone,[104] where both hypo- and hypersecretion (deficient- and excessive-secretion) of circulating androgens have negative effects on cognition.
Medical use[edit]
Main article: Testosterone (medication)
Testosterone is used as a medication for the treatment of males with too little or no natural testosterone production, certain forms of breast cancer,[10] and gender dysphoria in transgender men. This is known as hormone replacement therapy (HRT) or testosterone replacement therapy (TRT), which maintains serum testosterone levels in the normal range. Decline of testosterone production with age has led to interest in androgen replacement therapy.[105] It is unclear if the use of testosterone for low levels due to aging is beneficial or harmful.[106]
Testosterone is included in the World Health Organization's list of essential medicines, which are the most important medications needed in a basic health system.[107] It is available as a generic medication.[10] The price depends on the form of testosterone used.[108] It can be administered as a cream or transdermal patch that is applied to the skin, by injection into a muscle, as a tablet that is placed in the cheek, or by ingestion.[10]
Common side effects from testosterone medication include acne, swelling, and breast enlargement in males.[10] Serious side effects may include liver toxicity, heart disease, and behavioral changes.[10] Women and children who are exposed may develop virilization.[10] It is recommended that individuals with prostate cancer not use the medication.[10] It can cause harm if used during pregnancy or breastfeeding.[10]
Biological activity[edit]
Steroid hormone activity[edit]
The effects of testosterone in humans and other vertebrates occur by way of multiple mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors.[109][110] Androgens such as testosterone have also been found to bind to and activate membrane androgen receptors.[111][112][113]
Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5α-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5α-reductase. DHT binds to the same androgen receptor even more strongly than testosterone, so that its androgenic potency is about 5 times that of T.[114] The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.
Androgen receptors occur in many different vertebrate body system tissues, and both males and females respond similarly to similar levels. Greatly differing amounts of testosterone prenatally, at puberty, and throughout life account for a share of biological differences between males and females.
The bones and the brain are two important tissues in humans where the primary effect of testosterone is by way of aromatization to estradiol. In the bones, estradiol accelerates ossification of cartilage into bone, leading to closure of the epiphyses and conclusion of growth. In the central nervous system, testosterone is aromatized to estradiol. Estradiol rather than testosterone serves as the most important feedback signal to the hypothalamus (especially affecting LH secretion).[115] In many mammals, prenatal or perinatal "masculinization" of the sexually dimorphic areas of the brain by estradiol derived from testosterone programs later male sexual behavior.[116]
Neurosteroid activity[edit]
Testosterone, via its active metabolite 3α-androstanediol, is a potent positive allosteric modulator of the GABAA receptor.[117]
Testosterone has been found to act as an antagonist of the TrkA and p75NTR, receptors for the neurotrophin nerve growth factor (NGF), with high affinity (around 5 nM).[118][119][120] In contrast to testosterone, DHEA and DHEA sulfate have been found to act as high-affinity agonists of these receptors.[118][119][120]
Testosterone is an antagonist of the sigma σ1 receptor (Ki = 1,014 or 201 nM).[121] However, the concentrations of testosterone required for binding the receptor are far above even total circulating concentrations of testosterone in adult males (which range between 10 and 35 nM).[122]
Biochemistry[edit]
Human steroidogenesis, showing testosterone near bottom.[123]
Biosynthesis[edit]
Like other steroid hormones, testosterone is derived from cholesterol (see figure).[124] The first step in the biosynthesis involves the oxidative cleavage of the side-chain of cholesterol by cholesterol side-chain cleavage enzyme (P450scc, CYP11A1), a mitochondrial cytochrome P450 oxidase with the loss of six carbon atoms to give pregnenolone. In the next step, two additional carbon atoms are removed by the CYP17A1 (17α-hydroxylase/17,20-lyase) enzyme in the endoplasmic reticulum to yield a variety of C19 steroids.[125] In addition, the 3β-hydroxyl group is oxidized by 3β-hydroxysteroid dehydrogenase to produce androstenedione. In the final and rate limiting step, the C17 keto group androstenedione is reduced by 17β-hydroxysteroid dehydrogenase to yield testosterone.
The largest amounts of testosterone (>95%) are produced by the testes in men,[2] while the adrenal glands account for most of the remainder. Testosterone is also synthesized in far smaller total quantities in women by the adrenal glands, thecal cells of the ovaries, and, during pregnancy, by the placenta.[126] In the testes, testosterone is produced by the Leydig cells.[127] The male generative glands also contain Sertoli cells, which require testosterone for spermatogenesis. Like most hormones, testosterone is supplied to target tissues in the blood where much of it is transported bound to a specific plasma protein, sex hormone-binding globulin (SHBG).
Regulation[edit]
Hypothalamic–pituitary–testicular axis
In males, testosterone is synthesized primarily in Leydig cells. The number of Leydig cells in turn is regulated by luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In addition, the amount of testosterone produced by existing Leydig cells is under the control of LH, which regulates the expression of 17β-hydroxysteroid dehydrogenase.[128]
The amount of testosterone synthesized is regulated by the hypothalamic–pituitary–testicular axis (see figure to the right).[129] When testosterone levels are low, gonadotropin-releasing hormone (GnRH) is released by the hypothalamus, which in turn stimulates the pituitary gland to release FSH and LH. These latter two hormones stimulate the testis to synthesize testosterone. Finally, increasing levels of testosterone through a negative feedback loop act on the hypothalamus and pituitary to inhibit the release of GnRH and FSH/LH, respectively.
Factors affecting testosterone levels may include:
Age: Testosterone levels gradually reduce as men age.[130][131] This effect is sometimes referred to as andropause or late-onset hypogonadism.[132]
Exercise: Resistance training increases testosterone levels,[133] however, in older men, that increase can be avoided by protein ingestion.[134] Endurance training in men may lead to lower testosterone levels.[135]
Nutrients: Vitamin A deficiency may lead to sub-optimal plasma testosterone levels.[136] The secosteroid vitamin D in levels of 400–1000 IU/d (10–25 µg/d) raises testosterone levels.[137] Zinc deficiency lowers testosterone levels[138] but over-supplementation has no effect on serum testosterone.[139]
Weight loss: Reduction in weight may result in an increase in testosterone levels. Fat cells synthesize the enzyme aromatase, which converts testosterone, the male sex hormone, into estradiol, the female sex hormone.[140] However no clear association between body mass index and testosterone levels has been found.[141]
Miscellaneous: Sleep: (REM sleep) increases nocturnal testosterone levels.[142] Behavior: Dominance challenges can, in some cases, stimulate increased testosterone release in men.[143] Drugs: Natural or man-made antiandrogens including spearmint tea reduce testosterone levels.[144][145][146] Licorice can decrease the production of testosterone and this effect is greater in females.[147]
Distribution[edit]
The plasma protein binding of testosterone is 98.0 to 98.5%, with 1.5 to 2.0% free or unbound.[148] It is bound 65% to sex hormone-binding globulin (SHBG) and 33% bound weakly to albumin.[149]
Plasma protein binding of testosterone and dihydrotestosterone show
Metabolism[edit]
vte Testosterone metabolism in humans
Testosterone structures
The image above contains clickable linksTestosterone metabolism in humans. Conjugation (sulfation and glucuronidation) occurs both with testosterone and with all of the other steroids that have one or more available hydroxyl (-OH) groups in this diagram.
Both testosterone and 5α-DHT are metabolized mainly in the liver.[1][151] Approximately 50% of testosterone is metabolized via conjugation into testosterone glucuronide and to a lesser extent testosterone sulfate by glucuronosyltransferases and sulfotransferases, respectively.[1] An additional 40% of testosterone is metabolized in equal proportions into the 17-ketosteroids androsterone and etiocholanolone via the combined actions of 5α- and 5β-reductases, 3α-hydroxysteroid dehydrogenase, and 17β-HSD, in that order.[1][151][152] Androsterone and etiocholanolone are then glucuronidated and to a lesser extent sulfated similarly to testosterone.[1][151] The conjugates of testosterone and its hepatic metabolites are released from the liver into circulation and excreted in the urine and bile.[1][151][152] Only a small fraction (2%) of testosterone is excreted unchanged in the urine.[151]
In the hepatic 17-ketosteroid pathway of testosterone metabolism, testosterone is converted in the liver by 5α-reductase and 5β-reductase into 5α-DHT and the inactive 5β-DHT, respectively.[1][151] Then, 5α-DHT and 5β-DHT are converted by 3α-HSD into 3α-androstanediol and 3α-etiocholanediol, respectively.[1][151] Subsequently, 3α-androstanediol and 3α-etiocholanediol are converted by 17β-HSD into androsterone and etiocholanolone, which is followed by their conjugation and excretion.[1][151] 3β-Androstanediol and 3β-etiocholanediol can also be formed in this pathway when 5α-DHT and 5β-DHT are acted upon by 3β-HSD instead of 3α-HSD, respectively, and they can then be transformed into epiandrosterone and epietiocholanolone, respectively.[153][154] A small portion of approximately 3% of testosterone is reversibly converted in the liver into androstenedione by 17β-HSD.[152]
In addition to conjugation and the 17-ketosteroid pathway, testosterone can also be hydroxylated and oxidized in the liver by cytochrome P450 enzymes, including CYP3A4, CYP3A5, CYP2C9, CYP2C19, and CYP2D6.[155] 6β-Hydroxylation and to a lesser extent 16β-hydroxylation are the major transformations.[155] The 6β-hydroxylation of testosterone is catalyzed mainly by CYP3A4 and to a lesser extent CYP3A5 and is responsible for 75 to 80% of cytochrome P450-mediated testosterone metabolism.[155] In addition to 6β- and 16β-hydroxytestosterone, 1β-, 2α/β-, 11β-, and 15β-hydroxytestosterone are also formed as minor metabolites.[155][156] Certain cytochrome P450 enzymes such as CYP2C9 and CYP2C19 can also oxidize testosterone at the C17 position to form androstenedione.[155]
Two of the immediate metabolites of testosterone, 5α-DHT and estradiol, are biologically important and can be formed both in the liver and in extrahepatic tissues.[151] Approximately 5 to 7% of testosterone is converted by 5α-reductase into 5α-DHT, with circulating levels of 5α-DHT about 10% of those of testosterone, and approximately 0.3% of testosterone is converted into estradiol by aromatase.[2][151][157][158] 5α-Reductase is highly expressed in the male reproductive organs (including the prostate gland, seminal vesicles, and epididymides),[159] skin, hair follicles, and brain[160] and aromatase is highly expressed in adipose tissue, bone, and the brain.[161][162] As much as 90% of testosterone is converted into 5α-DHT in so-called androgenic tissues with high 5α-reductase expression,[152] and due to the several-fold greater potency of 5α-DHT as an AR agonist relative to testosterone,[163] it has been estimated that the effects of testosterone are potentiated 2- to 3-fold in such tissues.[164]
Levels[edit]
Total levels of testosterone in the body are 264 to 916 ng/dL in men age 19 to 39 years,[165] while mean testosterone levels in adult men have been reported as 630 ng/dL.[166] Levels of testosterone in men decline with age.[165] In women, mean levels of total testosterone have been reported to be 32.6 ng/dL.[167][168] In women with hyperandrogenism, mean levels of total testosterone have been reported to be 62.1 ng/dL.[167][168]
Testosterone levels in males and females show
Total testosterone levels in males throughout life show
Reference ranges for blood tests, showing adult male testosterone levels in light blue at center-left.
Measurement[edit]
Testosterone’s bioavailable concentration is commonly determined using the Vermeulen calculation or more precisely using the modified Vermeulen method,[174][175] which considers the dimeric form of sex-hormone-binding-globulin.[176]
Both methods use chemical equilibrium to derive the concentration of bioavailable testosterone: in circulation testosterone has two major binding partners, albumin (weakly bound) and sex-hormone-binding-globulin (strongly bound). These methods are described in detail in the accompanying figure.
Dimeric sex-hormone-binding-globulin with its testosterone ligands
Two methods for determining concentration of bioavailable testosterone.
History[edit]
A testicular action was linked to circulating blood fractions – now understood to be a family of androgenic hormones – in the early work on castration and testicular transplantation in fowl by Arnold Adolph Berthold (1803–1861).[177] Research on the action of testosterone received a brief boost in 1889, when the Harvard professor Charles-Édouard Brown-Séquard (1817–1894), then in Paris, self-injected subcutaneously a "rejuvenating elixir" consisting of an extract of dog and guinea pig testicle. He reported in The Lancet that his vigor and feeling of well-being were markedly restored but the effects were transient,[178] and Brown-Séquard's hopes for the compound were dashed. Suffering the ridicule of his colleagues, he abandoned his work on the mechanisms and effects of androgens in human beings.
In 1927, the University of Chicago's Professor of Physiologic Chemistry, Fred C. Koch, established easy access to a large source of bovine testicles — the Chicago stockyards — and recruited students willing to endure the tedious work of extracting their isolates. In that year, Koch and his student, Lemuel McGee, derived 20 mg of a substance from a supply of 40 pounds of bovine testicles that, when administered to castrated roosters, pigs and rats, remasculinized them.[179] The group of Ernst Laqueur at the University of Amsterdam purified testosterone from bovine testicles in a similar manner in 1934, but isolation of the hormone from animal tissues in amounts permitting serious study in humans was not feasible until three European pharmaceutical giants—Schering (Berlin, Germany), Organon (Oss, Netherlands) and Ciba (Basel, Switzerland)—began full-scale steroid research and development programs in the 1930s.
Nobel Prize winner, Leopold Ruzicka of Ciba, a pharmaceutical industry giant that synthesized testosterone.
The Organon group in the Netherlands were the first to isolate the hormone, identified in a May 1935 paper "On Crystalline Male Hormone from Testicles (Testosterone)".[180] They named the hormone testosterone, from the stems of testicle and sterol, and the suffix of ketone. The structure was worked out by Schering's Adolf Butenandt, at the Chemisches Institut of Technical University in Gdańsk.[181][182]
The chemical synthesis of testosterone from cholesterol was achieved in August that year by Butenandt and Hanisch.[183] Only a week later, the Ciba group in Zurich, Leopold Ruzicka (1887–1976) and A. Wettstein, published their synthesis of testosterone.[184] These independent partial syntheses of testosterone from a cholesterol base earned both Butenandt and Ruzicka the joint 1939 Nobel Prize in Chemistry.[182][185] Testosterone was identified as 17β-hydroxyandrost-4-en-3-one (C19H28O2), a solid polycyclic alcohol with a hydroxyl group at the 17th carbon atom. This also made it obvious that additional modifications on the synthesized testosterone could be made, i.e., esterification and alkylation.
The partial synthesis in the 1930s of abundant, potent testosterone esters permitted the characterization of the hormone's effects, so that Kochakian and Murlin (1936) were able to show that testosterone raised nitrogen retention (a mechanism central to anabolism) in the dog, after which Allan Kenyon's group[186] was able to demonstrate both anabolic and androgenic effects of testosterone propionate in eunuchoidal men, boys, and women. The period of the early 1930s to the 1950s has been called "The Golden Age of Steroid Chemistry",[187] and work during this period progressed quickly. Research in this golden age proved that this newly synthesized compound—testosterone—or rather family of compounds (for many derivatives were developed from 1940 to 1960), was a potent multiplier of muscle, strength, and well-being.[188]
Other animals[edit]
Testosterone is observed in most vertebrates. Testosterone and the classical nuclear androgen receptor first appeared in gnathostomes (jawed vertebrates).[189] Agnathans (jawless vertebrates) such as lampreys do not produce testosterone but instead use androstenedione as a male sex hormone.[190] Fish make a slightly different form called 11-ketotestosterone.[191] Its counterpart in insects is ecdysone.[192] The presence of these ubiquitous steroids in a wide range of animals suggest that sex hormones have an ancient evolutionary history.[193]
Note. This new plot (2021-02-17) uses a revised spectrometer UV flux calibration that reduces the difference between the sun and the sun+sky fluxes in the critical region around 310nm. It also reduces the irradiance of UVb lamp at this wavelength. The new calibration, based on my deuterium lamp and the NIST measurements of similar devices, should result in a significant increase in accuracy.
This plot illustrates the comparison between direct winter sunlight (solar altitude 22°), skylight, and an Hg fluorescent UVb lamp for vitamin D synthesis in the skin. It was made as part of my efforts to understand the conditions necessary to synthesise the precursor chain that results in calcitriol, which is the hormone that circulates in the body to produce the multiple beneficial of the vitamin.
This is based on just a single measurement and I consider it to be just a starting point for further investigations.
The black line spectrum on the left with a peak close to 300nm shows the action spectrum (inverse dose in cm^2/J, peak at 10.5) for the conversion of 7-dehydrocholesterol to previtamin D3 in human skin when illuminated by UV-b radiation (Reproduced in "Sunlight and Vitamin D, A global perspective for health" Matthias Wacker and Michael F. Holick (2013) from Holick M F. Vitamin D status: measurement, interpretation, and clinical application. Ann Epidemiol 2009; 19:73-8; PMID:18329892; dx.doi.org/10.1016/j.annepidem.2007.12.001.)
The blue and the red-dashed lines show measurements of the solar irradiance measured on a plane perpendicular to solar direction from a sky with some high level thin cirrus from Bath, UK on 2021-02-12. The blue-line spectrum extending into the UV is from a Maya2000Pro spectrometer using a cosine corrector with a relative but not absolute flux calibration. The red-dashed line is an intensity calibration from a visible light Sekonic C-7000 spectro-radiometer extending only as far as 380nm.
Parts of the horizon were obscured for these observations and so the irradiance measurements should be considered as upper limits.
The thin red line is a predicted solar radiance, using an extinction model with Rayleigh and aerosol scattering and ozone absorption elements, for an altitude of 22°. This is for direct sunlight and does not include any sky radiation. The blue shading then shows the contribution of the sky to the available effective UVb radiation.
The violet and green-dashed lines are measurements made with the same devices of a 13W UVB 10.0 mercury fluorescent lamp (Desert Terrarium Compact Fluorescent Lamp) measured from the side at a distance of 10cm.
These spectra illustrate the very marginal availability of direct solar UVb radiation capable of synthesising vitamin D in winter. The only effective radiation at this time comes from the sky, principally from light that is Rayleigh scattered above the ozone layer and follows a path to the ground from close to the local zenith that minimises the ozone absorption.
The calibrated UVb lamp spectrum shows that it is straightforward to provide more vitamin D effective UV radiation than that from winter Sun + skylight by using appropriate simple, relatively cheap, mercury discharge lamps that are sold to illuminate pet tortoises!
Quarta ed ultima parte di una piccola storia fotografica della Fai (Fabbrica Attrezzature Industriali) di Noventa Vicentina - Este.
La terna articolata prodotta dalla Fai (serie 5) viene migliorata con i nuovi modelli (serie 6) realizzati dal 1992.
Foto scattata in provincia di Pistoia, 24-02-2015
Storia dedicata all'amico Giorgio Mattiello, scomparso prematuramente, importante dipendente Fai e poi Komatsu.
Fai SynthEsis 692
Fourth and last part of a small photo story about Fai (Fabbrica Attrezzature Industriali) from Noventa Vicentina - Este.
The articulated backhoe loader produced by Fai (serie 5) is improved with new models (serie 6) manifactured since 1992.
Photo taken in the province of Pistoia, 24-feb-2015.
This story is dedicated to my friend Giorgio Mattiello died prematurely. He was a important employee of Fai and then Komatsu.
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Sichuanese opera (Chinese: 川劇 is a type of Chinese opera originating in China's Sichuan province around 1700.Today's Sichuan opera is a relatively recent synthesis of 5 historic melodic styles. Regionally Chengdu remains to be the main home of Sichuanese opera.
Overall the art form is well known for its singing, which is less constrained than that of the more popular Beijing opera form. Sichuan opera is more like a play than other forms of Chinese opera, and the acting is highly polished. The music accompanying Sichuanese opera utilizes a small gong and an instrument called a Muqin, which is similar to the Erhu.
The traditional formula is quite systematic with a combination of stunts like face-changing, tihuiyan, sword-hiding, fire-spitting and beard-changing with the plot and different characters.
Depending on the style, face paint is also limited compared to other related forms. Jing characters do not appear, and the only painted face characters are those with a small white patch in the middle of the face, which indicates a slightly evil character.The face paint colors are traditionally limited to black, red, white and grey.
Mars - Mars - Mars first person / human landing on Mars station tackling cutting-edge technology
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Enc:Special multi-purpose anti-radiation suit 50 million dollars
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Cutting-edge aerospace technology transfer 50 million dollars of new rocket radiation material 10 billion dollars against drugs microgravity $ 2 billion contact: Fangda337svb125@gmail.com,banxin123 @ gmail.com, mdin.jshmith @ gmail.com technology entry fee / technical margin of 1 million dollars , signed on demand
Table of Contents
Fangruida: human landing on Mars 10 cutting-edge technology
[Fangruida- human landing on Mars 10 innovative and sophisticated technologies]
Aerospace Science and space science and technology major innovation of the most critical of sophisticated technology R & D project
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Aerospace Science Space Science and Technology on behalf of the world's most cutting-edge leader in high technology, materials, mechatronics, information and communication, energy, biomedical, marine, aviation aerospace, microelectronics, computer, automation, intelligent biochips, use of nuclear energy, light mechanical and electrical integration, astrophysics, celestial chemistry, astrophysics and so a series of geological science and technology. Especially after the moon landing, the further development of mankind to Mars and other planets into the powerful offensive, the world's major powers eager to Daxian hand of God, increase investment, vigorously develop new sophisticated technology projects for space to space. Satellite, space station, the new spacecraft, the new space suits, the new radiation protection materials, intelligent materials, new manufacturing technology, communications technology, computer technology, detector technology, rover, rover technology, biomedical technology, and so one after another, is expected to greater breakthroughs and leaps. For example, rocket technology, spacecraft design, large power spacecraft, spacesuits design improvements, radiation multifunctional composite materials, life health care technology and space medicine, prevention against microgravity microgravity applicable drugs, tracking control technology, landing and return technology. Mars lander and returned safely to Earth as a top priority. Secondly, Mars, the Moon base and the use of transforming Mars, the Moon and other development will follow. Whether the former or the latter, are the modern aerospace science, space science basic research, applied basic research and applied research in the major cutting-edge technology. These major cutting-edge technology research and innovation, not only for human landing on Mars and the safe return of great significance, but for the entire space science, impact immeasurable universe sciences, earth sciences and human life. Here the most critical of the most important research projects of several sophisticated technology research and development as well as its core technology brief. Limit non-scientific techniques include non-technical limits of technology, the key lies in technology research and development of technology maturity, advanced technology, innovative, practical, reliable, practical application, business value and investment costs, and not simply like the idea mature technology achievements, difficult to put into things. This is the high-tech research and development, testing, prototype, test application testing, until the outcome of industrialization. Especially in aerospace technology, advanced, novelty, practicality, reliability, economy, maturity, commercial value and so on. For technical and research purely science fiction and the like may be irrelevant depth, but not as aerospace engineering and technology practice. Otherwise, Mars will become a dream fantasy, and even into settling crashed out of danger.
Regardless of the moon or Mars, many technical difficulties, especially a human landing on Mars and return safely to Earth, technical difficulties mainly in the following aspects. (Transformation of Mars and the Moon and other planets and detect other livable technology more complex and difficult, at this stage it is difficult to achieve and therefore not discussed in detail in this study). In fact, Mars will be the safe return of a full set of technology, space science, aerospace crucial scientific research development, its significance is not confined to Mars simply a return to scientific value, great commercial value, can not be measure.
1. Powered rocket, the spacecraft overall structural design not be too complex large, otherwise, the safety factor to reduce the risk of failure accidents. Fusion rocket engine main problem to be solved is the high-temperature materials and fuel ignition chamber (reaction chamber temperatures of up to tens of millions of supreme billion degrees), fissile class rocket engine whose essence is the miniaturization of nuclear reactors, and placed on the rocket. Nuclear rocket engine fuel as an energy source, with liquid hydrogen, liquid helium, liquid ammonia working fluid. Nuclear rocket engine mounted in the thrust chamber of the reactor, cooling nozzle, the working fluid delivery and control systems and other components. This engine due to nuclear radiation protection, exhaust pollution, reactor control and efficient heat exchanger design and other issues unresolved. Electrothermal rocket engine utilizing heat energy (resistance heating or electric arc heating) working medium (hydrogen, amines, hydrazine ), vaporized; nozzle expansion accelerated after discharged from the spout to generate thrust. Static rocket engine working fluid (mercury, cesium, hydrogen, etc.) from the tank enter the ionization chamber is formed thrust ionized into a plasma jet. Electric rocket engines with a high specific impulse (700-2500 sec), extremely long life (can be repeated thousands of times a starter, a total of up to thousands of hours of work). But the thrust of less than 100N. This engine is only available for spacecraft attitude control, station-keeping and the like. One nuclear - power rocket design is as follows: Firstly, the reactor heats water to make it into steam, and then the high-speed steam ejected, push the rocket. Nuclear rocket using hydrogen as working substance may be a better solution, it is one of the most commonly used liquid hydrogen rocket fuel rocket carrying liquid hydrogen virtually no technical difficulties. Heating hydrogen nuclear reactor, as long as it eventually reaches or exceeds current jet velocity hydrogen rocket engine jet speed, the same weight of the rocket will be able to work longer, it can accelerate the Rockets faster. Here there are only two problems: First, the final weight includes the weight of the rocket in nuclear reactors, so it must be as light as possible. Ultra-small nuclear reactor has been able to achieve. Furthermore, if used in outer space, we can not consider the problem of radioactive residues, simply to just one proton hydrogen nuclei are less likely to produce induced radioactivity, thus shielding layer can be made thinner, injected hydrogen gas can flow directly through the reactor core, it is not easy to solve, and that is how to get back at high speed heated gas is ejected.
Rocket engine with a nuclear fission reactor, based on the heating liquid hydrogen propellant, rather than igniting flammable propellant
High-speed heavy rocket is a major cutting-edge technology. After all, space flight and aircraft carriers, submarines, nuclear reactors differ greatly from the one hand, the use of traditional fuels, on the one hand can be nuclear reactor technology. From the control, for security reasons, the use of nuclear power rocket technology, safe and reliable overriding indicators. Nuclear atomic energy in line with the norms and rules of outer space. For the immature fetal abdominal hatchery technology, and resolutely reject use. This is the most significant development of nuclear-powered rocket principle.
Nuclear-powered spaceship for Use of nuclear power are three kinds:
The first method: no water or air space such media can not be used propeller must use jet approach. Reactor nuclear fission or fusion to produce a lot of heat, we will propellant (such as liquid hydrogen) injection, the rapid expansion of the propellant will be heated and then discharged from the engine speed tail thrust. This method is most readily available.
The second method: nuclear reactor will have a lot of fast-moving ions, these energetic particles moving very fast, so you can use a magnetic field to control their ejection direction. This principle ion rocket similar to the tail of the rocket ejected from the high-speed mobile ions, so that the recoil movement of a rocket. The advantage of this approach is to promote the unusually large ratio, without carrying any medium, continued strong. Ion engine, which is commonly referred to as "electric rocket", the principle is not complicated, the propellant is ionized particles,
Plasma Engine
Electromagnetic acceleration, high-speed spray. From the development trend, the US research scope covers almost all types of electric thrusters, but mainly to the development of ion engines, NASA in which to play the most active intake technology and preparedness plans. "
The third method: the use of nuclear explosions. It is a bold and crazy way, no longer is the use of a controlled nuclear reaction, but to use nuclear explosions to drive the ship, this is not an engine, and it is called a nuclear pulse rocket. This spacecraft will carry a lot of low-yield atomic bombs out one behind, and then detonated, followed by a spacecraft propulsion installation disk, absorbing the blast pushing the spacecraft forward. This was in 1955 to Orion (Project Orion) name of the project, originally planned to bring two thousand atomic bombs, Orion later fetal nuclear thermal rocket. Its principle is mounted on a small rocket reactor, the reactor utilizing thermal energy generated by the propellant is heated to a high temperature, high pressure and high temperature of the propellant from the high-speed spray nozzle, a tremendous impetus.
Common nuclear fission technologies, including nuclear pulse rocket engines, nuclear rockets, nuclear thermal rocket and nuclear stamping rockets to nuclear thermal rocket, for example, the size of its land-based nuclear power plant reactor structure than the much smaller, more uranium-235 purity requirements high, reaching more than 90%, at the request of the high specific impulse engine core temperature will reach about 3000K, require excellent high temperature properties of materials.
Research and test new IT technologies and new products and new technology and new materials, new equipment, things are difficult, design is the most important part, especially in the overall design, technical solutions, technical route, technical process, technical and economic particularly significant. The overall design is defective, technology there are loopholes in the program, will be a major technical route deviation, but also directly related to the success of research trials. so, any time, under any circumstances, a good grasp of the overall control of design, technical design, is essential. otherwise, a done deal, it is difficult save. aerospace technology research and product development is true.
3, high-performance nuclear rocket
Nuclear rocket nuclear fission and fusion energy can rocket rocket two categories. Nuclear fission and fusion produce heat, radiation and shock waves and other large amounts of energy, but here they are contemplated for use as a thermal energy rocket.
Uranium and other heavy elements, under certain conditions, will split their nuclei, called nuclear fission reaction. The atomic bomb is the result of nuclear fission reactions. Nuclear fission reaction to release energy, is a million times more chemical rocket propellant combustion energy. Therefore, nuclear fission energy is a high-performance rocket rockets. Since it requires much less propellant than chemical rockets can, so to its own weight is much lighter than chemical rockets energy. For the same quality of the rocket, the rocket payload of nuclear fission energy is much greater than the chemical energy of the rocket. Just nuclear fission energy rocket is still in the works.
Use of nuclear fission energy as the energy of the rocket, called the atomic rockets. It is to make hydrogen or other inert gas working fluid through the reactor, the hydrogen after the heating temperature quickly rose to 2000 ℃, and then into the nozzle, high-speed spray to produce thrust.
A vision plan is to use liquid hydrogen working fluid, in operation, the liquid hydrogen tank in the liquid hydrogen pump is withdrawn through the catheter and the engine cooling jacket and liquid hydrogen into hydrogen gas, hydrogen gas turbine-driven, locally expansion. Then by nuclear fission reactors, nuclear fission reactions absorb heat released, a sharp rise in temperature, and finally into the nozzle, the rapid expansion of high-speed spray. Calculations show that the amount of atomic payload rockets, rocket high chemical energy than 5-8 times.
Hydrogen and other light elements, under certain conditions, their nuclei convergent synthesis of new heavy nuclei, and release a lot of energy, called nuclear fusion reaction, also called thermonuclear reaction.
Using energy generated by the fusion reaction for energy rocket, called fusion energy rocket or nuclear thermal rockets. But it is also not only take advantage of controlled nuclear fusion reaction to manufacture hydrogen bombs, rockets and controlled nuclear fusion reaction needs still studying it.
Of course there are various research and development of rocket technology and technical solutions to try.
It is envisaged that the rocket deuterium, an isotope of hydrogen with deuterium nuclear fusion reaction of helium nuclei, protons and neutrons, and release huge amounts of energy, just polymerized ionized helium to temperatures up to 100 million degrees the plasma, and then nozzle expansion, high-speed ejection, the exhaust speed of up to 15,000 km / sec, atomic energy is 1800 times the rocket, the rocket is the chemical energy of 3700 times.
Nuclear rocket engine fuel as an energy source, with liquid hydrogen, liquid helium, liquid ammonia working fluid. Nuclear rocket engine mounted in the thrust chamber of the reactor, cooling nozzle, the working fluid delivery and control systems and other components. In a nuclear reactor, nuclear energy into heat to heat the working fluid, the working fluid is heated after expansion nozzle to accelerate to the speed of 6500 ~ 11,000 m / sec from the discharge orifice to produce thrust. Nuclear rocket engine specific impulse (250 to 1000 seconds) long life, but the technology is complex, apply only to long-term spacecraft. This engine due to nuclear radiation protection, exhaust pollution, reactor control and efficient heat exchanger design and other issues not resolved, is still in the midst of trials. Nuclear rocket technology is cutting-edge aerospace science technology, centralized many professional and technical sciences and aerospace, nuclear physics, nuclear chemistry, materials science, the long term future _-- wide width. The United States, Russia and Europe, China, India, Japan, Britain, Brazil and other countries in this regard have studies, in particular the United States and Russia led the way, impressive. Of course, at this stage of nuclear rocket technology, technology development there are still many difficulties. Fully formed, still to be. But humanity marching to the universe, nuclear reactor applications is essential.
Outer Space Treaty (International Convention on the Peaceful Uses of Outer Space) **
Use of Nuclear Power Sources in Outer Space Principle 15
General Assembly,
Having considered the report of its thirty-fifth session of the Committee on the Peaceful Uses of Outer Space and the Commission of 16 nuclear
It can be attached in principle on the use of nuclear power sources in outer space of the text of its report, 17
Recognize that nuclear power sources due to small size, long life and other characteristics, especially suitable for use even necessary
For some missions in outer space,
Recognizing also that the use of nuclear power sources in outer space should focus on the possible use of nuclear power sources
Those uses,
Recognizing also that the use of nuclear power sources should include or probabilistic risk analysis is complete security in outer space
Full evaluation is based, in particular, the public should focus on reducing accidental exposure to harmful radiation or radioactive material risk
risk,
Recognizing the need to a set of principles containing goals and guidelines in this regard to ensure the safety of outer space makes
With nuclear power sources,
Affirming that this set principles apply exclusively on space objects for non-power generation, which is generally characteristic
Mission systems and implementation of nuclear power sources in outer space on similar principles and used by,
Recognizing this need to refer to a new set of principles for future nuclear power applications and internationally for radiological protection
The new proposal will be revised
By the following principles on the use of nuclear power sources in outer space.
Principle 1. Applicability of international law
Involving the use of nuclear power sources in outer space activities should be carried out in accordance with international law, especially the "UN
Principles of the Charter "and" States in the Exploration and Use of Outer Space, including the Moon and Other Celestial Bodies Activities
Treaty "3
.
2. The principle terms
1. For the purpose of these principles, "launching State" and "launching State ......" two words mean, in related
Principles related to a time of nuclear power sources in space objects exercises jurisdiction and control of the country.
2. For the purpose of principle 9, wherein the definition of the term "launching State" as contained in that principle.
3. For the purposes of principle 3, the terms "foreseeable" and "all possible" two words are used to describe the actual hair
The overall likelihood of students that it is considered for safety analysis is credible possibilities for a class of things
Member or circumstances. "General concept of defense in depth" when the term applies to nuclear power sources in outer space refers to various settings
Count form and space operations replace or supplement the operation of the system in order to prevent system failures or mitigate thereafter
"Official Records of the General Assembly, Forty-seventh Session, Supplement No. 20" 16 (A / 47/20).
17 Ibid., Annex.
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fruit. To achieve this purpose is not necessarily required for each individual member has redundant safety systems. Given space
Use and special requirements of various space missions, impossible to any particular set of systems or features can be specified as
Necessary to achieve this purpose. For the purpose of Principle 3 (d) of paragraph 2, "made critical" does not include
Including such as zero-power testing which are fundamental to ensuring system safety required.
Principle 3. Guidelines and criteria for safe use
To minimize the risk of radioactive material in space and the number involved, nuclear power sources in outer space
Use should be limited to non-nuclear power sources in space missions can not reasonably be performed
1. General goals for radiation protection and nuclear safety
(A) States launching space objects with nuclear power sources on board shall endeavor to protect individuals, populations and the biosphere
From radiation hazards. The design and use of space objects with nuclear power sources on board shall ensure that risk with confidence
Harm in the foreseeable operational or accidental circumstances, paragraph 1 (b) and (c) to define acceptable water
level.
Such design and use shall also ensure that radioactive material does not reliably significant contamination of outer space.
(B) the normal operation of nuclear power sources in space objects, including from paragraph 2 (b) as defined in foot
High enough to return to the track, shall be subject to appropriate anti-radiation recommended by the International Commission on Radiological Protection of the public
Protection goals. During such normal operation there shall be no significant radiation exposure;
(C) To limit exposure in accidents, the design and construction of nuclear power source systems shall take into account the international
Relevant and generally accepted radiological protection guidelines.
In addition to the probability of accidents with potentially serious radiological consequences is extremely low, the nuclear power source
Design systems shall be safely irradiated limited limited geographical area, for the individual radiation dose should be
Limited to no more than a year 1mSv primary dose limits. Allows the use of irradiation year for some years 5mSv deputy agent
Quantity limit, but the average over a lifetime effective dose equivalent annual dose not exceed the principal limit 1mSv
degree.
Should make these conditions occur with potentially serious radiological consequences of the probability of the system design is very
small.
Criteria mentioned in this paragraph Future modifications should be applied as soon as possible;
(D) general concept of defense in depth should be based on the design, construction and operation of systems important for safety. root
According to this concept, foreseeable safety-related failures or malfunctions must be capable of automatic action may be
Or procedures to correct or offset.
It should ensure that essential safety system reliability, inter alia, to make way for these systems
Component redundancy, physical separation, functional isolation and adequate independence.
It should also take other measures to increase the level of safety.
2. The nuclear reactor
(A) nuclear reactor can be used to:
39
(I) On interplanetary missions;
(Ii) the second high enough orbit paragraph (b) as defined;
(Iii) low-Earth orbit, with the proviso that after their mission is complete enough to be kept in a nuclear reactor
High on the track;
(B) sufficiently high orbit the orbital lifetime is long enough to make the decay of fission products to approximately actinides
Element active track. The sufficiently high orbit must be such that existing and future outer space missions of crisis
Risk and danger of collision with other space objects to a minimum. In determining the height of the sufficiently high orbit when
It should also take into account the destroyed reactor components before re-entering the Earth's atmosphere have to go through the required decay time
between.
(C) only 235 nuclear reactors with highly enriched uranium fuel. The design shall take into account the fission and
Activation of radioactive decay products.
(D) nuclear reactors have reached their operating orbit or interplanetary trajectory can not be made critical state
state.
(E) nuclear reactor design and construction shall ensure that, before reaching the operating orbit during all possible events
Can not become critical state, including rocket explosion, re-entry, impact on ground or water, submersion
In water or water intruding into the core.
(F) a significant reduction in satellites with nuclear reactors to operate on a lifetime less than in the sufficiently high orbit orbit
For the period (including during operation into the sufficiently high orbit) the possibility of failure, there should be a very
Reliable operating system, in order to ensure an effective and controlled disposal of the reactor.
3. Radioisotope generators
(A) interplanetary missions and other spacecraft out of Earth's gravitational field tasks using radioactive isotopes
Su generator. As they are stored after completion of their mission in high orbit, the Earth can also be used
track. We are required to make the final treatment under any circumstances.
(B) Radioisotope generators shall be protected closed systems, design and construction of the system should
Ensure that in the foreseeable conditions of the track to withstand the heat and aerodynamic forces of re-entry in the upper atmosphere, orbit
Conditions including highly elliptical or hyperbolic orbits when relevant. Upon impact, the containment system and the occurrence of parity
Physical morpheme shall ensure that no radioactive material is scattered into the environment so you can complete a recovery operation
Clear all radioactive impact area.
Principle 4. Safety Assessment
1. When launching State emission consistent with the principles defined in paragraphs 1, prior to the launch in applicable under the
Designed, constructed or manufactured the nuclear power sources, or will operate the space object person, or from whose territory or facility
Transmits the object will be to ensure a thorough and comprehensive safety assessment. This assessment shall cover
All relevant stages of space mission and shall deal with all systems involved, including the means of launching, the space level
Taiwan, nuclear power source and its equipment and the means of control and communication between ground and space.
2. This assessment shall respect the principle of 3 contained in the guidelines and criteria for safe use.
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3. The principle of States in the Exploration and Use, including the Moon and Other Celestial Bodies Outer Space Activities Article
Results of about 11, this safety assessment should be published prior to each transmit simultaneously to the extent feasible
Note by the approximate intended time of launch, and shall notify the Secretary-General of the United Nations, how to be issued
This safety assessment before the shot to get the results as soon as possible.
Principle 5. Notification of re-entry
1. Any State launching a space object with nuclear power sources in space objects that failed to produce discharge
When radioactive substances dangerous to return to the earth, it shall promptly notify the country concerned. Notice shall be in the following format:
(A) System parameters:
(I) Name of launching State, including which may be contacted in the event of an accident to Request
Information or assistance to obtain the relevant authorities address;
(Ii) International title;
(Iii) Date and territory or location of launch;
(Iv) the information needed to make the best prediction of orbit lifetime, trajectory and impact region;
(V) General function of spacecraft;
(B) information on the radiological risk of nuclear power source:
(I) the type of power source: radioisotopes / reactor;
(Ii) the fuel could fall into the ground and may be affected by the physical state of contaminated and / or activated components, the number of
The amount and general radiological characteristics. The term "fuel" refers to as a source of heat or power of nuclear material.
This information shall also be sent to the Secretary-General of the United Nations.
2. Once you know the failure, the launching State shall provide information on the compliance with the above format. Information should as far as possible
To be updated frequently, and in the dense layers of the Earth's atmosphere is expected to return to a time when close to the best increase
Frequency of new data, so that the international community understand the situation and will have sufficient time to plan for any deemed necessary
National contingency measures.
3. It should also be at the same frequency of the latest information available to the Secretary-General of the United Nations.
Principle 6. consultation
5 According to the national principles provide information shall, as far as reasonably practicable, other countries
Requirements to obtain further information or consultations promptly reply.
Principle 7. Assistance to States
1. Upon receipt of expected with nuclear power sources on space objects and their components will return through the Earth's atmosphere
After know that all countries possessing space monitoring and tracking facilities, in the spirit of international cooperation, as soon as possible to
The Secretary-General of the United Nations and the countries they may have made space objects carrying nuclear power sources
A fault related information, so that the States may be affected to assess the situation and take any
It is considered to be the necessary precautions.
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2. In carrying space objects with nuclear power sources back to the Earth's atmosphere after its components:
(A) launching State shall be requested by the affected countries to quickly provide the necessary assistance to eliminate actual
And possible effects, including nuclear power sources to assist in identifying locations hit the Earth's surface, to detect the re substance
Quality and recovery or cleanup activities.
(B) All countries with relevant technical capabilities other than the launching State, and with such technical capabilities
International organizations shall, where possible, in accordance with the requirements of the affected countries to provide the necessary co
help.
When according to the above (a) and subparagraph (b) to provide assistance, should take into account the special needs of developing countries.
Principle 8. Responsibility
In accordance with the States in the Exploration and Use of Outer Space, including the Moon and Other Celestial Bodies activities, including the principles of Article
About Article, States shall bear international responsibility for their use of nuclear power sources in outer space relates to the activities
Whether such activities are carried on by governmental agencies or non-governmental entities, and shall bear international responsibility to ensure that this
Such activities undertaken by the country in line with the principles of the Treaty and the recommendations contained therein. If it involves the use of nuclear power sources
Activities in outer space by an international organization, should be done by the international organizations and States to participate in the organization
Undertakes to comply with the principles of the Treaty and the recommendations contained in these responsibilities.
Principle 9. Liability and Compensation
1. In accordance with the principle of States in the Exploration and Use, including the Moon and Other Celestial Bodies Outer Space Activities Article
And the Convention on International Liability for Damage Caused by Space Objects covenant of Article 7
Provisions, which launches or on behalf of the State
Each State launching a space object and each State from which territory or facility a space object is launched
Kinds of space object or damage caused by components shall bear international liability. This fully applies to this
Kind of space object carrying a nuclear power source case. Two or more States jointly launch a space object,
Each launching State shall in accordance with the above Article of the Convention for any damages jointly and severally liable.
2. Such countries under the aforesaid Convention shall bear the damages shall be in accordance with international law and fair and reasonable
The principles set out in order to provide for damages to make a claim on behalf of its natural or juridical persons, national or
International organizations to restore to the state before the occurrence of the damage.
3. For the purposes of this principle, compensation should be made to include reimbursement of the duly substantiated expenses for search, recovery and clean
Cost management work, including the cost of providing assistance to third parties.
10. The principle of dispute settlement
Since the implementation of these principles will lead to any dispute in accordance with the provisions of the UN Charter, by negotiation or
Other established procedures to resolve the peaceful settlement of disputes.
Here quoted the important provisions of the United Nations concerning the use of outer space for peaceful nuclear research and international conventions, the main emphasis on the Peaceful Uses of provisions related constraints .2 the use of nuclear rockets in outer space nuclear studies, etc., can cause greater attention in nuclear power nuclear rocket ship nuclear research, manufacture, use and other aspects of the mandatory hard indicators. this scientists, engineering and technical experts are also important constraints and requirements. as IAEA supervision and management as very important.
2. radiation. Space radiation is one of the greatest threats to the safety of the astronauts, including X-rays, γ-rays, cosmic rays and high-speed solar particles. Better than aluminum protective effect of high polymer composite materials.
3. Air. Perhaps the oxygen needed to rely on oxidation-reduction reaction of hydrogen and ilmenite production of water, followed by water electrolysis to generate oxygen. Mars oxygen necessary for survival but also from the decomposition of water, electrolytically separating water molecules of oxygen and hydrogen, this oxygen equipment has been successfully used in the International Space Station. Oxygen is released into the air to sustain life, the hydrogen system into the water system.
4. The issue of food waste recycling. At present, the International Space Station on the use of dehumidifiers, sucked moisture in the air to be purified, and then changed back to drinkable water. The astronauts' urine and sweat recycling. 5. water. The spacecraft and the space station on purification system also makes urine and other liquids can be purified utilization. 6. microgravity. In microgravity or weightlessness long-term space travel, if protective measures shall not be treated, the astronauts will be muscle atrophy, bone softening health. 7. contact. 8. Insulation, 9 energy. Any space exploration are inseparable from the energy battery is a new super hybrid energy storage device, the asymmetric lead-acid batteries and supercapacitors in the same compound within the system - and the so-called inside, no additional separate electronic control unit, this is an optimal combination. The traditional lead-acid battery PbO2 monomer is a positive electrode plate and a negative electrode plate spongy Pb composition, not a super cell. : Silicon solar cells, multi-compound thin film solar cells, multi-layer polymer-modified electrode solar cells, nano-crystalline solar cells, batteries and super class. For example, the solar aircraft .10. To protect the health and life safety and security systems. Lysophosphatidic acid LPA is a growth factor-like lipid mediators, the researchers found that this substance can on apoptosis after radiation injury and animal cells was inhibited. Stable lysophosphatidic acid analogs having the hematopoietic system and gastrointestinal tract caused by acute radiation sickness protection, knockout experiments show that lysophosphatidic acid receptors is an important foundation for the protection of radiation injury. In addition to work under high pressure, the astronauts face a number of health threats, including motion sickness, bacterial infections, blindness space, as well as psychological problems, including toxic dust. In the weightless environment of space, the astronaut's body will be like in preadolescents, as the emergence of various changes.
Plantar molt
After the environment to adapt to zero gravity, the astronaut's body will be some strange changes. Weightlessness cause fluid flow around the main flow torso and head, causing the astronauts facial swelling and inflammation, such as nasal congestion. During long-term stay in space
Bone and muscle loss
Most people weightlessness caused by the impact may be known bone and muscle degeneration. In addition, the calcium bones become very fragile and prone to fracture, which is why some of the astronauts after landing need on a stretcher.
Space Blindness
Space Blindness refers astronaut decreased vision.
Solar storms and radiation is one of the biggest challenges facing the long-term space flight. Since losing the protection of Earth's magnetic field, astronauts suffer far more than normal levels of radiation. The cumulative amount of radiation exposure in low earth orbit them exceeded by workers close to nuclear reactors, thereby increasing the risk of cancer.
Prolonged space flight can cause a series of psychological problems, including depression or mood swings, vulnerability, anxiety and fear, as well as other sequelae. We are familiar with the biology of the Earth, the Earth biochemistry, biophysics, after all, the Earth is very different astrophysics, celestial chemistry, biophysics and astrophysics, biochemistry and other celestial bodies. Therefore, you must be familiar with and adapt to these differences and changes.
Osteoporosis and its complications ranked first in the space of disease risk.
Long-term health risks associated with flying Topics
The degree of influence long-term biological effects of radiation in human flight can withstand the radiation and the maximum limit of accumulated radiation on physiology, pathology and genetics.
Physiological effects of weightlessness including: long-term bone loss and a return flight after the maximum extent and severity of the continued deterioration of other pathological problems induced by the; maximum flexibility and severity of possible long-term Flight Center in vascular function.
Long-term risk of disease due to the high risk of flight stress, microbial variation, decreased immune function, leading to infections
Radiation hazards and protection
1) radiation medicine, biology and pathway effects Features
Radiation protection for interplanetary flight, since the lack of protective effect of Earth's magnetic field, and by the irradiation time is longer, the possibility of increased radiation hazard.
Analysis of space flight medical problems that may occur, loss of appetite topped the list, sleep disorders, fatigue and insomnia, in addition, space sickness, musculoskeletal system problems, eye problems, infections problems, skin problems and cardiovascular problems
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Development of diagnostic techniques in orbit, the development of the volume of power consumption, features a wide range of diagnostic techniques, such as applied research of ultrasound diagnostic techniques in the abdominal thoracic trauma, bone, ligament damage, dental / sinus infections and other complications and integrated;
Actively explore in orbit disposal of medical technology, weightlessness surgical methods, development of special surgical instruments, the role of narcotic drugs and the like.
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However, space technology itself is integrated with the use of the most advanced technology, its challenging technical reserves and periodic demanding
With the continuous development of science and technology, space agencies plan a manned landing on the moon and Mars, space exploration emergency medicine current concern.
Space sickness
In the weightless environment of space, in the weightless environment of space, surgery may be extremely difficult and risky.
Robot surgeons
Space disease in three days after entering the space started to ease, although individual astronauts might subsequently relapse. January 2015 NASA declared working on a fast, anti-nausea and nasal sprays. In addition, due to the zero-gravity environment, and anti-nausea drugs can only be administered by injection or transdermal patches manner.
Manned spaceflight in the 21st century is the era of interplanetary flight, aerospace medicine is closely watched era is the era of China's manned space flourish. Only the central issue, and grasp the opportunity to open up a new world of human survival and development.
Various emergency contingency measures in special circumstances. Invisible accident risk prevention. Enhancing drugs and other screening methods immunity aerospace medicine and tissue engineering a microgravity environment. Drug mixture of APS, ginseng polysaccharides, Ganoderma lucidum polysaccharides, polysaccharides and Lentinan, from other compounds. Drug development space syndrome drug, chemical structure modification will be an important part.
These issues are very sensitive, cutting-edge technology is a major difficulty landing on Mars. Countries in the world, especially the world's major space powers in the country strategies and technical research, the results of all kinds continue to emerge. United States, Russia, China, Europe, India, Japan and other countries is different. United States, Russia extraordinary strength. Many patented technology and health, and most belong to the top-secret technology. Especially in aerospace engineering and technological achievements is different from the general scientific literature, practical, commercial, industrial great, especially the performance of patents, know-how, technical drawings, engineering design and other aspects. Present Mars and return safely to Earth, the first manned, significance, everything is hard in the beginning, especially the first person to land on Mars This Mars for Human Sciences Research Mars, the moon, the earth, the solar system and the universe, life and other significant. Its far greater than the value of direct investments and business interests.
In addition, it is the development of new materials, suitable for deep space operations universe, life, and other detection, wider field.
Many aerospace materials, continuous research and development of materials are key areas of aerospace development, including material rocket, the spacecraft materials, the suit materials, radiation materials, materials and equipment, instruments, materials and so on biochemistry.
Temperature metal-based compound with a metal matrix composite body with a more primordial higher temperature strength, creep resistance, impact resistance, thermal fatigue and other excellent high temperature performance.
In B, C, SiC fiber reinforced Ti3Al, TiAl, Ni3Al intermetallic matrix composites, etc.
W Fiber Reinforced with nickel-based, iron-based alloys as well as SiC, TiB2, Si3N4 and BN particle reinforced metal matrix composites
High temperature service conditions require the development of ceramic and carbon-based composite materials, etc., not in this eleven Cheung said.
Fuel storage
In order to survive in space, people need many things: food, oxygen, shelter, and, perhaps most importantly, fuel. The initial quality Mars mission somewhere around 80 percent of the space launch humans will be propellant. The fuel amount of storage space is very difficult.
This difference in low Earth orbit cause liquid hydrogen and liquid oxygen - rocket fuel - vaporization.
Hydrogen is particularly likely to leak out, resulting in a loss of about 4% per month.
When you want to get people to Mars speed to minimize exposure to weightlessness and space radiation hazards
Mars
Landings on the Martian surface, they realized that they reached the limit. The rapid expansion of the thin Martian atmosphere can not be very large parachute, such as those that will need to be large enough to slow down, carry human spacecraft.
Therefore, the parachute strong mass ratio, high temperature resistance, Bing shot performance and other aspects of textile materials used have special requirements, in order to make a parachute can be used in rockets, missiles, Yu arrows spacecraft and other spacecraft recovery, it is necessary to improve the canopy heat resistance, a high melting point polymeric fiber fabric used, the metal fabric, ceramic fiber fabrics, and other devices.
Super rigid parachute to help slow the landing vehicle.
Spacecraft entered the Martian atmosphere at 24,000 km / h. Even after slowing parachute or inflatable, it will be very
Once we have the protection of the Earth magnetic field, the solar radiation will accumulate in the body, a huge explosion threw the spacecraft may potentially lethal doses of radiation astronauts.
In addition to radiation, the biggest challenge is manned trip to Mars microgravity, as previously described.
The moon is sterile. Mars is another case entirely.
With dust treatment measures.
Arid Martian environment to create a super-tiny dust particles flying around the Earth for billions of years.
Apollo moon dust encountered. Ultra-sharp and abrasive lunar dust was named something that can clog the basic functions of mechanical damage. High chloride salt, which can cause thyroid problems in people.
Mars geological structure and geological structure of the moon, water on Mars geology, geology of the Moon is very important, because he, like the Earth's geology is related to many important issues. Water, the first element of life, air, temperature, and complex geological formations are geological structure. Cosmic geology research methods, mainly through a variety of detection equipment equipped with a space probe, celestial observations of atmospheric composition, composition and distribution of temperature, pressure, wind speed, vertical structure, composition of the solar wind, the water, the surface topography and Zoning, topsoil the composition and characteristics of the component surface of the rock, type and distribution, stratigraphic sequence, structural system and the internal shell structure.
Mars internal situation only rely on its surface condition of large amounts of data and related information inferred. It is generally believed that the core radius of 1700 km of high-density material composition; outsourcing a layer of lava, it is denser than the Earth's mantle some; outermost layer is a thin crust. Compared to other terrestrial planets, the lower the density of Mars, which indicates that the Martian core of iron (magnesium and iron sulfide) with may contain more sulfur. Like Mercury and the Moon, Mars and lack active plate movement; there is no indication that the crust of Mars occurred can cause translational events like the Earth like so many of folded mountains. Since there is no lateral movement in the earth's crust under the giant hot zone relative to the ground in a stationary state. Slight stress coupled with the ground, resulting in Tharis bumps and huge volcano. For the geological structure of Mars is very important, which is why repeated explorations and studies of Martian geological reasons.
Earth's surface
Each detector component landing site soil analysis:
Element weight percent
Viking 1
Oxygen 40-45
Si 18-25
Iron 12-15
K 8
Calcium 3-5
Magnesium 3-6
S 2-5
Aluminum 2-5
Cesium 0.1-0.5
Core
Mars is about half the radius of the core radius, in addition to the primary iron further comprises 15 to 17% of the sulfur content of lighter elements is also twice the Earth, so the low melting point, so that the core portion of a liquid, such as outside the Earth nuclear.
Mantle
Nuclear outer coating silicate mantle.
Crust
The outermost layer of the crust.
Crustal thickness obtained, the original thickness of the low north 40 km south plateau 70 kilometers thick, an average of 50 kilometers, at least 80 km Tharsis plateau and the Antarctic Plateau, and in the impact basin is thin, as only about 10 kilometers Greece plains.
Canyon of Mars there are two categories: outflow channels (outflow channel) and tree valley (valley network). The former is very large, it can be 100 km wide, over 2000 km long, streamlined, mainly in the younger Northern Hemisphere, such as the plain around Tyre Chris Canyon and Canyon jam.
In addition, the volcanic activity sometimes lava formation lava channels (lava channel); crustal stress generated by fissures, faults, forming numerous parallel extending grooves (fossa), such as around the huge Tharsis volcanic plateau radially distributed numerous grooves, which can again lead to volcanic activity.
Presumably, Mars has an iron as the main component of the nucleus, and contains sulfur, magnesium and other light elements, the nuclear share of Mars, the Earth should be relatively small. The outer core is covered with a thick layer of magnesium-rich silicate mantle, the surface of rocky crust. The density of Earth-like planets Mars is the lowest, only 3.93g / cc.
Hierarchy
The crust
Lunar core
The average density of the Moon is 3.3464 g / cc, the solar system satellites second highest (after Aiou). However, there are few clues mean lunar core is small, only about 350 km radius or less [2]. The core of the moon is only about 20% the size of the moon, the moon's interior has a solid, iron-rich core diameter of about 240 kilometers (150 miles); in addition there is a liquid core, mainly composed of iron outer core, about 330 km in diameter (205 miles), and for the first time compared with the core of the Earth, considered as the earth's outer core, like sulfur and oxygen may have lighter elements [4].
Chemical elements on the lunar surface constituted in accordance with its abundance as follows: oxygen (O), silicon (Si), iron (Fe), magnesium (Mg), calcium (Ca), aluminum (Al), manganese (Mn), titanium ( Ti). The most abundant is oxygen, silicon and iron. The oxygen content is estimated to be 42% (by weight). Carbon (C) and nitrogen (N) only traces seem to exist only in trace amounts deposited in the solar wind brings.
Lunar Prospector from the measured neutron spectra, the hydrogen (H) mainly in the lunar poles [2].
Element content (%)
Oxygen 42%
Silicon 21%
Iron 13%
Calcium 8%
Aluminum 7%
Magnesium 6%
Other 3%
Lunar surface relative content of each element (% by weight)
Moon geological history is an important event in recent global magma ocean crystallization. The specific depth is not clear, but some studies have shown that at least a depth of about 500 kilometers or more.
Lunar landscape
Lunar landscape can be described as impact craters and ejecta, some volcanoes, hills, lava-filled depressions.
Regolith
TABLE bear the asteroid and comets billions of years of bombardment. Over time, the impact of these processes have already broken into fine-grained surface rock debris, called regolith. Young mare area, regolith thickness of about 2 meters, while the oldest dated land, regolith thickness of up to 20 meters. Through the analysis of lunar soil components, in particular the isotopic composition changes can determine the period of solar activity. Solar wind gases possible future lunar base is useful because oxygen, hydrogen (water), carbon and nitrogen is not only essential to life, but also may be useful for fuel production. Lunar soil constituents may also be as a future source of energy.
Here, repeatedly stressed that the geological structure and geological structure of celestial bodies, the Earth, Moon, Mars, or that this human existence and development of biological life forms is very important, especially in a series of data Martian geological structure geological structure is directly related to human landing Mars and the successful transformation of Mars or not. for example, water, liquid water, water, oxygen, synthesis, must not be taken lightly.
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Mars landing 10 Technology
Aerospace Science and space science and technology major innovation of the most critical of sophisticated technology R & D project
[
"1" rocket propulsion technology ion fusion nuclear pulse propulsion rocket powered high-speed heavy rocket technology, space nuclear reactors spacecraft] brought big problems reflected in the nuclear reaction, nuclear radiation on spacecraft launch, control, brakes and other impact.
In particular, for the future of nuclear power spacecraft, the need to solve the nuclear reactor design, manufacture, control, cooling, radiation shielding, exhaust pollution, high thermoelectric conversion efficiency and a series of technical problems.
In particular, nuclear reactors produce radiation on astronauts' health will pose a great threat, which requires the spacecraft to be nuclear radiation shielding to ensure astronaut and ship the goods from radiation and heat from the reactor influence, but this will greatly increase the weight of the detector.
Space nuclear process applications, nuclear reaction decay is not a problem, but in a vacuum, ultra-low temperature environment, the nuclear reaction materials, energy transport materials have very high demands.
Space facing the reality of a nuclear reactor cooling cooling problems. To prevent problems with the reactor, "Washington" aircraft carrier to take four heavy protective measures for the radiation enclosed in the warship. These four measures are: the fuel itself, fuel storage pressure vessel, reactor shell and the hull. US Navy fuel all metal fuel, designed to take the impact resistance of the war, does not release fission product can withstand more than 50 times the gravity of the impact load; product of nuclear fission reactor fuel will never enter loop cooling water. The third layer of protection is specially designed and manufactured the reactor shell. The fourth layer is a very strong anti-impact combat ship, the reactor is arranged in the center of the ship, very safe. Engage in a reactor can only be loaded up to the aircraft, so as to drive the motor, and then drive the propeller. That is the core advantage of the heat generated by the heated gas flow, high temperature high pressure gas discharge backward, thereby generating thrust.
.
After installation AMPS1000 type nuclear power plant, a nuclear fuel assembly: He is a core member of the nuclear fuel chain reaction. Usually made into uranium dioxide, of which only a few percent uranium-235, and most of it is not directly involved in the nuclear fission of uranium 238. The uranium dioxide sintered into cylindrical pieces, into a stainless steel or a zirconium alloy do metal tubes called fuel rods or the original, then the number of fuel rods loaded metal cylinder in an orderly composition of the fuel assembly, and finally put a lot of vertical distribution of fuel assemblies in the reactor.
Nuclear reactor pressure vessel is a housing for containing nuclear fuel and reactor internals, for producing high-quality high-strength steel is made to withstand the pressure of dozens MPa. Import and export of the coolant in the pressure vessel.
The top of the pressure vessel closure, and can be used to accommodate the fixed control rod drive mechanism, pressure vessel head has a semi-circular, flat-topped.
Roof bolt: used to connect the locking pressure vessel head, so that the cylinder to form a completely sealed container.
Neutron Source: Plug in nuclear reactors can provide sufficient neutron, nuclear fuel ignition, to start to enhance the role of nuclear reactors and nuclear power. Neutron source generally composed of radium, polonium, beryllium, antimony production. Neutron source and neutron fission reactors are fast neutron, can not cause fission of uranium 235, in order to slow down, we need to moderator ---- full of pure water in a nuclear reactor. Aircraft carriers, submarines use nuclear reactor control has proven more successful.
Rod: has a strong ability to absorb neutrons, driven by the control rod drive mechanism, can move up and down in a nuclear reactor control rods within the nuclear fuel used to start, shut down the nuclear reactor, and maintain, regulate reactor power. Hafnium control rods in general, silver, indium, cadmium and other metals production.
Control rod drive mechanism: He is the executive body of nuclear reactors operating system and security protection systems, in strict accordance with requirements of the system or its operator control rod drives do move up and down in a nuclear reactor, nuclear reactor for power control. In a crisis situation, you also can quickly control rods fully inserted into the reactor in order to achieve the purpose of the emergency shutdown
Upper and lower support plate: used to secure the fuel assembly. High temperature and pressure inside the reactor is filled with pure water (so called pressurized water reactors), on the one hand he was passing through a nuclear reactor core, cooling the nuclear fuel, to act as a coolant, on the other hand it accumulates in the pressure vessel in play moderated neutrons role, acting as moderator.
Water quality monitoring sampling system:
Adding chemical system: under normal circumstances, for adding hydrazine, hydrogen, pH control agents to the primary coolant system, the main purpose is to remove and reduce coolant oxygen, high oxygen water suppression equipment wall corrosion (usually at a high temperature oxygen with hydrogen, especially at low temperatures during startup of a nuclear reactor with added hydrazine oxygen); when the nuclear reactor control rods stuck for some reason can not shutdown time by the the system can inject the nuclear reactor neutron absorber (such as boric acid solution), emergency shutdown, in order to ensure the safety of nuclear submarines.
Water system: a loop inside the water will be reduced at work, such as water sampling and analysis, equipment leaks, because the shutdown process cooling water and reduction of thermal expansion and contraction.
Equipment cooling water system:
Pressure safety systems: pressure reactor primary coolant system may change rapidly for some reason, the need for effective control. And in severe burn nuclear fuel rods, resulting in a core melt accident, it is necessary to promptly increase the pressure. Turn the regulator measures the electric, heating and cooling water. If necessary, also temporary startup booster pump.
Residual Heat Removal System: reactor scram may be due to an accident, such as when the primary coolant system of the steam generator heat exchanger tube is damaged, it must be urgently closed reactors.
Safety Injection System: The main components of this system is the high-pressure injection pump.
Radioactive waste treatment systems:
Decontamination Systems: for the removal of radioactive deposits equipment, valves, pipes and accessories, and other surfaces.
Europe, the United States and Russia and other countries related to aircraft carriers, submarines, icebreakers, nuclear-powered research aircraft, there are lots of achievements use of nuclear energy, it is worth analysis. However, nuclear reactor technology, rocket ships and the former are very different, therefore, requires special attention and innovative research. Must adopt a new new design techniques, otherwise, fall into the stereotype, it will avail, nothing even cause harm Aerospace.
[ "2" spacecraft structure]
[ "3"] radiation technology is the use of deep-sea sedimentation fabric fabrics deepwater technology development precipitated silver metal fibers or fiber lint and other materials and micronaire value between 4.1 to 4.3 fibers made from blends. For radiation protection field, it greatly enhances the effects of radiation and service life of clothing. Radiation resistant fiber) radiation resistant fiber - fiber polyimide polyimide fibers
60 years the United States has successfully developed polyimide fibers, it has highlighted the high temperature, radiation-resistant, fire-retardant properties.
[ "4" cosmic radiation resistant clothing design multifunctional anti-aging, wear underwear] ① comfort layer: astronauts can not wash clothes in a long flight, a lot of sebum, perspiration, etc. will contaminate underwear, so use soft, absorbent and breathable cotton knitwear making.
② warm layer: at ambient temperature range is not the case, warm layer to maintain a comfortable temperature environment. Choose warm and good thermal resistance large, soft, lightweight material, such as synthetic fibers, flakes, wool and silk and so on.
③ ventilation and cooling clothes clothes
Spacesuit
In astronaut body heat is too high, water-cooled ventilation clothing and clothing to a different way of heat. If the body heat production more than 350 kcal / h (ventilated clothes can not meet the cooling requirements, then that is cooled by a water-cooled suit. Ventilating clothing and water-cooled multi-use compression clothing, durable, flexible plastic tubing, such as polyvinyl chloride pipe or nylon film.
④ airtight limiting layer:
⑤ insulation: astronaut during extravehicular activities, from hot or cold insulation protection. It multilayer aluminized polyester film or a polyimide film and sandwiched between layers of nonwoven fabric to be made.
⑥ protective cover layer: the outermost layer of the suit is to require fire, heat and anti-space radiation on various factors (micrometeorites, cosmic rays, etc.) on the human body. Most of this layer with aluminized fabric.
New space suits using a special radiation shielding material, double design.
And also supporting spacesuit helmet, gloves, boots and so on.
[ "5" space - Aerospace biomedical technology, space, special use of rescue medication Space mental health care systems in space without damage restful sleep positions - drugs, simple space emergency medical system
]
[ "6" landing control technology, alternate control technology, high-performance multi-purpose landing deceleration device (parachute)]
[ "7" Mars truck, unitary Mars spacecraft solar energy battery super multi-legged (rounds) intelligent robot] multifunction remote sensing instruments on Mars, Mars and more intelligent giant telescope
[8 <> Mars warehouse activities, automatic Mars lander - Automatic start off cabin
]
[ "9" Mars - spacecraft docking control system, return to the system design]
Space flight secondary emergency life - support system
Spacecraft automatic, manual, semi-automatic operation control, remote control switch system
Automatic return spacecraft systems, backup design, the spacecraft automatic control operating system modular blocks of]
[10 lunar tracking control system
Martian dust storms, pollution prevention, anti-corrosion and other special conditions thereof
Electric light aircraft, Mars lander, Mars, living spaces, living spaces Mars, Mars entry capsule, compatible utilization technology, plant cultivation techniques, nutrition space - space soil]
Aerospace technology, space technology a lot, a lot of cutting-edge technology. Human landing on Mars technology bear the brunt. The main merge the human landing on Mars 10 cutting-edge technology, in fact, these 10 cutting-edge technology, covering a wide range, focused, and is the key to key technologies. They actually shows overall trends and technology Aerospace Science and Technology space technology. Human triumph Mars and safe return of 10 cutting-edge technology is bound to innovation. Moreover, in order to explore the human Venus, Jupiter satellites and the solar system, the Milky Way and other future development of science and laid the foundation guarantee. But also for the transformation of human to Mars, the Moon and other planets livable provides strong technical support. Aerospace Science and Technology which is a major support system.
Preparation of oxygen, water, synthesis, temperature, radiation, critical force confrontation. Regardless of the moon or Mars, survive three elements bear the brunt.
Chemical formula: H₂O
Formula: H-O-H (OH bond between two angle 104.5 °).
Molecular Weight: 18.016
Chemical Experiment: water electrolysis. Formula: 2H₂O = energized = 2H₂ ↑ + O₂ ↑ (decomposition)
Molecules: a hydrogen atom, an oxygen atom.
Ionization of water: the presence of pure water ionization equilibrium following: H₂O == == H⁺ + OH⁻ reversible or irreversible H₂O + H₂O = = H₃O⁺ + OH⁻.
NOTE: "H₃O⁺" hydronium ions, for simplicity, often abbreviated as H⁺, more accurate to say the H9O4⁺, the amount of hydrogen ion concentration in pure water material is 10⁻⁷mol / L.
Electrolysis of water:
Water at DC, decomposition to produce hydrogen and oxygen, this method is industrially prepared pure hydrogen and oxygen 2H₂O = 2H₂ ↑ + O₂ ↑.
. Hydration Reaction:
Water with an alkaline active metal oxides, as well as some of the most acidic oxide hydration reaction of unsaturated hydrocarbons.
Na₂O + H₂O = 2NaOH
CaO + H₂O = Ca (OH) ₂
SO₃ + H₂O = H₂SO₄
P₂O₅ + 3H₂O = 2H₃PO₄ molecular structure
CH₂ = CH₂ + H₂O ← → C₂H₅OH
6. The diameter of the order of magnitude of 10 water molecules negative power of ten, the water is generally believed that a diameter of 2 to 3 this organization. water
7. Water ionization:
In the water, almost no water molecules ionized to generate ions.
H₂O ← → H⁺ + OH⁻
Heating potassium chlorate or potassium permanganate preparation of oxygen
Pressurized at low temperatures, the air into a liquid, and then evaporated, since the boiling point of liquid nitrogen is -196 deg.] C, lower than the boiling point of liquid oxygen (-183 ℃), so the liquid nitrogen evaporated from the first air, remaining the main liquid oxygen.
Of course, the development
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Coventry's Cathedral is a unique synthesis of old a new, born of wartime suffering and forged in the spirit of postwar optimism, famous for it's history and for being the most radically modern of Anglican cathedrals. Two cathedral's stand side by side, the ruins of the medieval building, destroyed by incendiary bombs in 1940 and the bold new building designed by Basil Spence and opened in 1962.
It is a common misconception that Coventry lost it's first cathedral in the wartime blitz, but the bombs actually destroyed it's second; the original medieval cathedral was the monastic St Mary's, a large cruciform building believed to have been similar in appearance to Lichfield Cathedral (whose diocese it shared). Tragically it became the only English cathedral to be destroyed during the Reformation, after which it was quickly quarried away, leaving only scant fragments, but enough evidence survives to indicate it's rich decoration (some pieces were displayed nearby in the Priory Visitors Centre, sadly since closed). Foundations of it's apse were found during the building of the new cathedral in the 1950s, thus technically three cathedrals share the same site.
The mainly 15th century St Michael's parish church became the seat of the new diocese of Coventry in 1918, and being one of the largest parish churches in the country it was upgraded to cathedral status without structural changes (unlike most 'parish church' cathedrals created in the early 20th century). It lasted in this role a mere 22 years before being burned to the ground in the 1940 Coventry Blitz, leaving only the outer walls and the magnificent tapering tower and spire (the extensive arcades and clerestoreys collapsed completely in the fire, precipitated by the roof reinforcement girders, installed in the Victorian restoration, that buckled in the intense heat).
The determination to rebuild the cathedral in some form was born on the day of the bombing, however it wasn't until the mid 1950s that a competition was held and Sir Basil Spence's design was chosen. Spence had been so moved by experiencing the ruined church he resolved to retain it entirely to serve as a forecourt to the new church. He envisaged the two being linked by a glass screen wall so that the old church would be visible from within the new.
Built between 1957-62 at a right-angle to the ruins, the new cathedral attracted controversy for it's modern form, and yet some modernists argued that it didn't go far enough, after all there are echoes of the Gothic style in the great stone-mullioned windows of the nave and the net vaulting (actually a free-standing canopy) within. What is exceptional is the way art has been used as such an integral part of the building, a watershed moment, revolutionising the concept of religious art in Britain.
Spence employed some of the biggest names in contemporary art to contribute their vision to his; the exterior is adorned with Jacob Epstein's triumphant bronze figures of Archangel Michael (patron of the cathedral) vanquishing the Devil. At the entrance is the remarkable glass wall, engraved by John Hutton with strikingly stylised figures of saints and angels, and allowing the interior of the new to communicate with the ruin. Inside, the great tapestry of Christ in majesty surrounded by the evangelistic creatures, draws the eye beyond the high altar; it was designed by Graham Sutherland and was the largest tapestry ever made.
However one of the greatest features of Coventry is it's wealth of modern stained glass, something Spence resolved to include having witnessed the bleakness of Chartres Cathedral in wartime, all it's stained glass having been removed. The first window encountered on entering is the enormous 'chess-board' baptistry window filled with stunning abstract glass by John Piper & Patrick Reyntiens, a symphony of glowing colour. The staggered nave walls are illuminated by ten narrow floor to ceiling windows filled with semi-abstract symbolic designs arranged in pairs of dominant colours (green, red, multi-coloured, purple/blue and gold) representing the souls journey to maturity, and revealed gradually as one approaches the altar. This amazing project was the work of three designers lead by master glass artist Lawrence Lee of the Royal College of Art along with Keith New and Geoffrey Clarke (each artist designed three of the windows individually and all collaborated on the last).
The cathedral still dazzles the visitor with the boldness of it's vision, but alas, half a century on, it was not a vision to be repeated and few of the churches and cathedrals built since can claim to have embraced the synthesis of art and architecture in the way Basil Spence did at Coventry.
The cathedral is generally open to visitors most days. For more see below:-
A kid learns to walk with his mother and aunt in the alleys of Shakharibazar.
Visit my photoblog: Photo Synthesis
Copyright 2014 Aneek Mustafa Anwar
Contact: labouffon@gmail.com
Image taken 08.06.2018 by David Moth. At Aérodrome de Biscarrosse - Parentis Rue Costes et Bellonte 40600 Biscarrosse (LFBS)..Aquitaine,France
a view of the town hall tower, the cathedral tower, the arts tower (university of sheffield) and park hill.
sheffield, england
The Westerbork Synthesis Radio Telescope (WSRT) is an aperture synthesis interferometer near camp Westerbork, north of the village of Westerbork, Midden-Drenthe, in the northeastern Netherlands. It consists of a linear array of 14 antennas with a diameter of 25 metres arranged on a 2.7 km East-West line.
Entrance was prohibited, so had to use a telezoom. Would have loved to get closer and use my 14-24.
Oh well...:)
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Name: Jémes Yardlé
Age: spans great winds of time
Alignment: Bad
Abilities: Can transfer solar energies from plants giving strength and the ability to shoot energy beams.
Origin-
At the edge of the Universe is Htrae, a planet that is the exact twin of earth, save few a few bizarre differences. This planet is on the brink of falling out of the universe and as a result bizarre creatures began to appear. One of these creatures, a solar powered spider came through and bit serial procrastinator Jémes Yardlé giving him solar powered abilities. Yardlé used his powers to hijack a space shuttle and escaped to our planet, eliminating and replacing his double pathetically easily. Having integrated himself, Yardlé became a super villain, robbing banks and targeting anyone who puts the word lol after a YouTube comment even though nothing to do with the comment is a humorous!
after synthesis (2015)
earlier drawings can be seen here: www.flickr.com/photos/badgerofmystery/albums/721576507333...
El artista Luis Macías juega con la imagen, el color y los mecanismos de visión del espectador en la obra que muestra desde hoy en la Blueproject Foundation de Barcelona, en la exposición "Spectral Synthesis", resultado de la tercera residencia artística llevada a cabo en el centro.
Anteriormente, la Blueproject había exhibido los proyectos "The Keeper", de Pedro Torres, y "Oh sween encounter of these other worlds", de las danesas Barbara Amalie Skovmand Thomsen y Marie-Louise Andersson.
La imagen, el color y los mecanismos de visión del espectador han sido los factores clave de su proyecto, que parecen representar "un retorno a la base de colores", y fue precisamente el tratamiento que les dio lo que le determinó su acceso a la fundación, ha asegurado hoy Aurélien Le Genissel, gestor artístico de Blueproject Foundation.
Mediante una visión analógica y un retorno al elemento físico y táctil de la representación del color, Macías presenta cinco esculturas cinemáticas basadas en intermitencias e incandescencias que muestran al espectador diversas representaciones de los colores primarios y secundarios.
La pieza "Screen Synthesis", que utiliza un fotograma de 35 milímetros como una pantalla de led intermitente de colores aleatorios frente a una proyección de 16 milímetros, comparte la entrada de la sala con "?" (infinito), que muestra un juego de sobreimpresión cromática con cuatro proyectores de diapositivas en constante movimiento.
"Spectrocopy" es un estudio de colores a partir de proyecciones enfrentadas en 16 milímetros que juegan con la ilusión de percepción, igual que las otras dos obras del artista, "Primary Synthesis" y "Secondary Synthesis", que se mezclan a partir de intermitencias estroboscópicas.
"Autodidacta" confeso, Luís Macías, nacido en Platja d'Aro pero criado en Alicante, desarrolla en paralelo a este proyecto su especialización en cine expandido, lo que le ha permitido participar en eventos como el festival Sónar, el Festival Internacional de VideoArte de Camagüey (Cuba), el Crossroads International Film Festival (San Francisco) o la Microscope Gallery (Brooklyn).
The shutter design of Canon S90 allows for some neat 6-rayed sunbursts. That coupled with its ultra-wide angle lens allows for some very cool perpectives.
This was one such experiment where I kept the camera level with the lawn so as to see the blades of grass up close and framed the sunlight and the water sprinklers with it. Let me know if you like the result.
Shot at UCSB.
Press L to view it large and on black
Coventry's Cathedral is a unique synthesis of old a new, born of wartime suffering and forged in the spirit of postwar optimism, famous for it's history and for being the most radically modern of Anglican cathedrals. Two cathedral's stand side by side, the ruins of the medieval building, destroyed by incendiary bombs in 1940 and the bold new building designed by Basil Spence and opened in 1962.
It is a common misconception that Coventry lost it's first cathedral in the wartime blitz, but the bombs actually destroyed it's second; the original medieval cathedral was the monastic St Mary's, a large cruciform building believed to have been similar in appearance to Lichfield Cathedral (whose diocese it shared). Tragically it became the only English cathedral to be destroyed during the Reformation, after which it was quickly quarried away, leaving only scant fragments, but enough evidence survives to indicate it's rich decoration (some pieces were displayed nearby in the Priory Visitors Centre, sadly since closed). Foundations of it's apse were found during the building of the new cathedral in the 1950s, thus technically three cathedrals share the same site.
The mainly 15th century St Michael's parish church became the seat of the new diocese of Coventry in 1918, and being one of the largest parish churches in the country it was upgraded to cathedral status without structural changes (unlike most 'parish church' cathedrals created in the early 20th century). It lasted in this role a mere 22 years before being burned to the ground in the 1940 Coventry Blitz, leaving only the outer walls and the magnificent tapering tower and spire (the extensive arcades and clerestoreys collapsed completely in the fire, precipitated by the roof reinforcement girders, installed in the Victorian restoration, that buckled in the intense heat).
The determination to rebuild the cathedral in some form was born on the day of the bombing, however it wasn't until the mid 1950s that a competition was held and Sir Basil Spence's design was chosen. Spence had been so moved by experiencing the ruined church he resolved to retain it entirely to serve as a forecourt to the new church. He envisaged the two being linked by a glass screen wall so that the old church would be visible from within the new.
Built between 1957-62 at a right-angle to the ruins, the new cathedral attracted controversy for it's modern form, and yet some modernists argued that it didn't go far enough, after all there are echoes of the Gothic style in the great stone-mullioned windows of the nave and the net vaulting (actually a free-standing canopy) within. What is exceptional is the way art has been used as such an integral part of the building, a watershed moment, revolutionising the concept of religious art in Britain.
Spence employed some of the biggest names in contemporary art to contribute their vision to his; the exterior is adorned with Jacob Epstein's triumphant bronze figures of Archangel Michael (patron of the cathedral) vanquishing the Devil. At the entrance is the remarkable glass wall, engraved by John Hutton with strikingly stylised figures of saints and angels, and allowing the interior of the new to communicate with the ruin. Inside, the great tapestry of Christ in majesty surrounded by the evangelistic creatures, draws the eye beyond the high altar; it was designed by Graham Sutherland and was the largest tapestry ever made.
However one of the greatest features of Coventry is it's wealth of modern stained glass, something Spence resolved to include having witnessed the bleakness of Chartres Cathedral in wartime, all it's stained glass having been removed. The first window encountered on entering is the enormous 'chess-board' baptistry window filled with stunning abstract glass by John Piper & Patrick Reyntiens, a symphony of glowing colour. The staggered nave walls are illuminated by ten narrow floor to ceiling windows filled with semi-abstract symbolic designs arranged in pairs of dominant colours (green, red, multi-coloured, purple/blue and gold) representing the souls journey to maturity, and revealed gradually as one approaches the altar. This amazing project was the work of three designers lead by master glass artist Lawrence Lee of the Royal College of Art along with Keith New and Geoffrey Clarke (each artist designed three of the windows individually and all collaborated on the last).
The cathedral still dazzles the visitor with the boldness of it's vision, but alas, half a century on, it was not a vision to be repeated and few of the churches and cathedrals built since can claim to have embraced the synthesis of art and architecture in the way Basil Spence did at Coventry.
The cathedral is generally open to visitors most days. For more see below:-