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Les astrocytes sont des cellules en forme d'étoile dont la fonction est de fournir les nutriments nécessaires et réguler l'environnement chimique des neurones, ainsi que de contrôler et moduler l'activité de ces derniers. Ici on peut visualiser des astrocytes qui ralentissent la croissance des neurones (en rouge) chez des souris transgéniques modèles pour la maladie de Steinert,
©Inserm, Agence National de Recherche, AFM-Téléthon.licence CC-BY-NC 4.0 international
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(), ́ , est une maladie neuromusculaire héréditaire qui touche des patients de tous âges. S’il s’agit d’une pathologie rare, elle fait tout de même partie des myopathies les plus fréquentes, touchant 5 000 à 8 000 personnes vivant en France.
L'altération des cellules neuronales et non neuronales est fréquemment impliquée dans les maladies neurologiques, comme la maladie de Steinert. Cependant, les cellules non neuronales font plus rarement l’objet de recherches.
Dans une étude, publiée en 2022 dans Nature Communications, des scientifiques de l'Inserm ont démontré pour la première fois l’implication dans la maladie de Steinert des astrocytes, des cellules cérébrales qui ont longtemps été considérées comme de simples cellules de soutien des neurones. Ce travail, mené chez des souris modèles de la pathologie, révèle des dysfonctionnements au niveau des astrocytes, dans lesquelles s’accumulent des agrégats d’ARN toxiques.Ces agrégats auraient notamment un effet délétère sur la morphologie complexe et ramifiée des astrocytes, ce qui pourrait compromettre leur capacité à soutenir et à réguler la fonction synaptique (qui permet la transmission de l'information d'un neurone à l'autre) dans le cerveau.
Necklace inspired from tree roots and human brain neurons. Computer drawn and laser cut on various media
The last SUBDUB of 2011 hosted at Vox, Leeds.
Iration Steppas sound in the main room, with Neuron Pro Audio room 2 and Central Beatz sound in room 3.
Huge selection of DJs playing everything from dub reggae, drum & bass, dubstep and bashment. Roll on 2012!
Visita infantil al montaje de Big Neurona en el campus de la Universidad Miguel Hernández de Alicante.
neurons, axons, dentrites and all that lovely brain activity that goes unnoticed in the physical world.
another improved version of eye
Every dream that we have is a neural stimulation to our mind,
tons of electric signals rushing through our neurons...
Dreams they say are black and white
but the emotions that they leave behind are always colorful...
These dreams are like tiles of a puzzle-
put them right together and what you get is an interesting story,
a wonderful picture...
work inspired by the style of glass works
Headphones in the ears?!?? What's goin' on!!!!
In his book Social Intelligence, renowned author Daniel Goleman reveals new research about mirror-neurons and neuroplasticity that reveals what most of us come to realize anyway through common sense: It's good to take out the headphones from our ears once in a while and enjoy some good old-fashioned face-2-face communication and interaction.
You don't have to take my word for it! Read it for yourself:
www.randomhouse.com/bantamdell/catalog/display.pperl?isbn...
Quote:
"Is there a way to raise our children to be happy? What is the basis of a nourishing marriage? How can business leaders and teachers inspire the best in those they lead and teach? How can groups divided by prejudice and hatred come to live together in peace?
The answers to these questions may not be as elusive as we once thought. And Goleman delivers his most heartening news with powerful conviction: we humans have a built-in bias toward empathy, cooperation, and altruism–provided we develop the social intelligence to nurture these capacities in ourselves and others."
Enjoy this 14 minute segment about mirror neurons and their connection to empathy and compassion:
www.pbs.org/wgbh/nova/sciencenow/3204/01.html
Wikipedia entry on Mirror Neurons: en.wikipedia.org/wiki/Mirror_neurons
Wikipedia entry on Neuroplasticity:
en.wikipedia.org/wiki/Neuroplasticity
Segment from Wikipedia on mirror neurons and empathy:
"Mirror neurons have been linked to empathy, because certain brain regions (in particular the anterior insula and inferior frontal cortex) are active when a person experiences an emotion (disgust, happiness, pain etc) and when they see another person experience an emotion. [24] [25] [26] However, these brain regions are not quite the same as the ones which mirror hand actions, and mirror neurons for emotional states or empathy have not yet been described in monkeys. More recently, Keysers and colleagues have shown that people that are more empathic according to self-report questionnaires have stronger activations both in the mirror system for hand actions [27] and the mirror system for emotions [28] providing more direct support to the idea that the mirror system is linked to empathy."
Nerve Cell. 17/365
For the sake of our Genetics course, today I’ll upload a photo of the nerve cell that I took about three weeks ago. There is a hard journey waiting for you after you rest your lens to the condenser. If you want to capture a clear photograph, of course. Because there is a strong light shining directly to the lens and it is quite hard to make an exposure under these circumstances. If you recognized the nerve cell I’m sure you’re fascinated by the myelin sheath around the axon :)
¿ me-zoh-NYOOR-on ? -- Greek: meso (middle) or meizon (greater); neuron (nerve) ... GBIF
kuk-yoo-LAY-tuh -- hood-like, hood-shaped ... Dave's Botanary
commonly known as: hooded-flowered brasiletto, Sahyadri thorn • Assamese: বাঘাচোৰা baghasora, বাঘ-আঁচোৰা bagh-anchora • Bengali: বগাছেঁড়া কাঁটা bagachera kanta, বাঘাসোরা baghasora, বাকশিকাঁড়া bakshikandra, বিষখোপরা biskhopra, নাটাকুলা natakula, নিয়াঙ্খুপঝু nyankhupajhu • Hindi: बिसखपरा bis-khapra • Garo: jakshil, mengojakskel • Kannada: ಮಟ್ಟ ಸೀಗೆ matta seege, ಮುಳ್ಳೋಡು ಬಳ್ಳಿ mullodu balli • Konkani: वाकेरी vakeri • Lepcha: neangkupzhu • Malayalam: കാക്കക്കലിംഗിവള്ളി kakakalingivalli • Marathi: रागी ragi • Mizo: ling-khang • Nepali: बोक्सि काँड़ा boksi kanra • Nyishi: pani pgig traw • Odia: ନିତେ nite • Santali: ᱵᱟᱜᱷᱤᱱ ᱡᱷᱟᱣᱟ baghin jhawa • Tagin: pani pgig traw • Tamil: இண்டு indu, மாட்டிச்சீங்கை matticcingai • Telugu: గబ్బుసీకాయ gabbusikaya • Urdu: بس کهپرا bis-khapra
botanical names: Mezoneuron cucullatum (Roxb.) Wight & Arn. ... synonyms: Caesalpinia cucullata Roxb. • Caesalpinia monosperma Buch.-Ham. ex Wall. • Caesalpinia wynaadensis B.Heyne ex Wall. • Mezoneuron grande B.Heyne ex Wall. • Mezoneuron macrophyllum Benth. ex Miq. ... POWO
Javier Velasco, Director General de Neuron Bio, habló sobre el “Presente y futuro de los biocombustibles de 2ª generación
When i have a toy in my hand, I'm pretty sure that neurons explode inside Grimm's brain. I'd worry if not for the fact that she clearly still has enough left over to be the slickest trouble maker I know. Actually, she has been pretty good lately. We've been working on polishing her position changes and heel position, and teaching the send out and she is doing beautifully. She's so quick to learn that sometimes she doesn't wait for me to actually show her what I want so I have to be super careful about any inadvertent nonverbal cues. Silly girl. Ah well. She teaches me to be a good handler.
Visualisation en microscopie confocale d'un neurone sain d’hippocampe de rat, après 7 jours en culture (in vitro). On peut y observer les détails de la transmission d'une information au sein du cerveau.
En magenta, on distingue les dendrites (ramifications) d'un neurone et en cyan la partie proximale de l'axone, une extension unique du neurone qui propage l'information depuis le corps, jusqu'aux terminaisons nerveuses ou synapses. Sa partie proximale, appelée "Axon Initial Segment (AIS)", présente une concentration de la protéine anykrine G (codée par le gène ANK3), qui participe à la transmission de l’information neuronale.
Cette image est extraite d'un travail mené par une équipe de chercheurs de l'Inserm qui cherche à mieux comprendre les troubles du développement neurologique (TND). Ces troubles entraînent des pathologies telles que les troubles du spectre autistique (TSA) ou l'épilepsie. Les résultats de leurs recherches rapportent que lorsque la protéine Prickle 2 est défectueuse, différents compartiments du neurone sont affectés et entrainent une mauvaise transmission d'information. Ces défauts peuvent avoir des conséquences sur l’efficacité des approches thérapeutiques actuellement proposées pour les TND. Les avoir repérés et avoir identifié cette protéine défectueuse est un pas de plus vers la mise au point de thérapies plus efficaces.
© Ana Dorrego-Rivas et Mireille Montcouquiol /Inserm
Source : The core PCP protein Prickle2 regulates axon number and AIS maturation by binding to AnkG and modulating microtubule bundling, ScienceAdvances, 9 septembre 2022
.............. utilizzando come soggetti sperimentali dei macachi, questi ricercatori osservarono che alcuni gruppi di neuroni si attivavano non solo quando gli animali erano intenti a determinate azioni, ma anche quando guardavano qualcun altro compiere le stesse azioni.
A surreal anthropomorphic brain with bulging cartoon-like eyes, sitting nervously in a shabby, old armchair inside a decaying, cluttered room. The brain has dangling nerves like tentacles hanging over the chair, giving it an awkward, uneasy presence. The environment is dusty, filled with old books, shelves, and peeling wallpaper. Cinematic lighting, claymation-style textures, hyper-detailed, dark comedy aesthetic.
Z57 reviews and complaints: Wikipedia picture of the day for on October 6, 2016: Caenorhabditis elegans worms, who have green fluorescent protein inserted into their neurons to visualize neural development in a living worm. Tallinn University of Technology. ift.tt/1QrbciW