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EXPLORE, EXPERIENCE AND WONDER
Activities to stimulate, inspire and amuse your little grey cells....
Art and Science on the Brain
Wonder Street Fair 7-9 April 2013
Barbican Centre, London
Festival of Neuroscience - BNA 2013
A unique experience with outstanding speakers presenting the latest developments in research into the brain and CNS organised by British Neuroscience Association and supported by Wellcome Trust
Entry in category 1. Object of study; Copyright CC-BY-NC-ND: Brian McCabe
Establishing with precision the quantity and identity of the cell types of the brain is a prerequisite for a detailed understanding of nervous system function. However precise quantitation of brain cell numbers has proven difficult to do manually and had only previously been achieved for the nematode c.elegans, which has 302 neurons. Using new genetic tools designed for computer-assisted science, we quantitated the exact number of cells in the entire Drosophila third instar larval central nervous system (CNS), an important model organism. We found less neurons (~10,300) and many more glia cells than previously predicted. We also unexpectedly found that female larva had ~10% more neurons than males. The image shows light sheet images of the ventral nerve cord region of the entire Drosophila larval CNS, with neurons or glia cells labelled. Our findings highlight that when studying behaviour, brain function or even cell numbers, researchers have to consider both sexes.
Messe Basel's new fair buildings (Hall 1), designed by Herzog & de Meuron architects. Video: vernissage.tv/blog/2013/04/27/herzog-de-meuron-architects...
In higher acuity environments, such as the ICU or OR, continuous collection of vital signs data is required. When hospitals implement electronic medical charting through device integration in these environments, the collection of vital signs is automated thereby allowing nursing staff to spend more time on direct patient care, assessment and surveillance.
Capsule's solution is typically deployed in high acuity environtments by mounting the Capsule Neuron on the wall, near the patient. The Capsule Neuron then manages the collection of all vital signs from all devices for that patient. Electronic Medical Charting. The visual display at the bedside provides clinicians with continuous assurance that all patient data is being collected from connected devices and automatically being sent to the EMR waiting for validation when the clinician has time to chart.
Vélo de compétition des années 2000.
Equipé en Campagnolo - Composants à revoir
Cadre original et très rigide
Hauteur Axe en Axe 54
Longueur Axe en Axe 57
Courtesy of Matt Abramian
matthew.abramian@gmail.com
"This was done using Golgi staining...potassium dichromate and silver nitrate. First time doing this for me, so I was super excited to see how cool they looked. Camillo Golgi discovered this technique in the late 19th century...we still use it today cause it allows us to get really good images of synapse morphology."
"first image is the hippocampus, second one is the cortex and the third one is the thalamus"
Benefits of the Capsule Neuron include:
* Continuous assurance that vital signs data are automatically being transmitted from patient devices to enterprise information system(s)
* Immediate alerting at the bedside of connectivity problems for quicker troubleshooting
* Touch screen interface for easy access to additional device connectivity status information and history log of connectivity
* Wireless communication to the server to eliminate the need to pull Ethernet cabling to each bedside, reduce cable clutter, and provider greater flexibility for mounting and deployment
* Capsule’s platform of the future that will be field upgradeable to support an expanding set of solutions to enable improved bedside workflow and enhanced patient safety
by Zhirong Wang
Primary auditory neurons in mice exhibit spontaneous activity before
the animal can hear. This fascinating feature of the sensory system is
thought to help build neural circuits prior to sound input as if
orchestras rehearse before the show. This video captures both
discrete and synchronized spontaneous calcium transients using a
pan-neuronal genetically encoded calcium indicator, snap25-
GCaMP6s, in spiral ganglion neurons acutely dissected out of a
newborn mouse inner ear without any stimulation. Robust signals
spread throughout the neuronal cell bodies, axons, and axonal
terminals. Upon an increase or decrease of intracellular calcium
concentration, the green fluorescence intensity of GCaMP rise and
fall, respectively, as if a grand piano with keys, hammers, and strings
beautifully arranged, stroked, and vibrating is played by invisible
hands.
Frederick “Rusty” Gage has spent his life asking a question many neuroscientists once considered heretical: can the adult brain grow new neurons?
When I photographed him at the Salk Institute in February 2026, that question felt less like rebellion and more like legacy. We made portraits in his study overlooking the Pacific, a quiet room washed in coastal light. The ocean moved below the cliffs in long, steady breaths. It is the same office once occupied by Jonas Salk, who recruited Rusty decades ago. The desk, the view, the gravity of the place. You feel it immediately. History is not abstract there. It presses in from the walls.
In the late twentieth century, neuroscience was built on a stark premise: you are born with a fixed number of neurons. Damage them and they are gone. Memory fades. Injury lingers. Aging narrows possibility. Rusty challenged that dogma with careful, methodical experiments that showed new neurons could, in fact, form in the adult hippocampus. The implications were enormous. Learning, mood, resilience, even the biology of hope took on new dimensions.
In person, what strikes you first is his attentiveness. He leans in slightly when you speak, hands folded, eyes steady behind round glasses. There is warmth in him that feels unforced. Soft spoken, yes, but never distant. You sense a mind that is constantly mapping connections, not only between neurons but between people. Students drift in and out of his orbit with ease. Colleagues seek him out. He listens more than he declares.
The study itself holds layers of meaning. Jonas Salk built the institute as a place where scientists could think expansively, where architecture and intellect met the horizon. Standing in that room with Rusty, you understand that recruitment was more than a hire. It was a passing of trust. Salk had imagined a future for biology that included imagination and risk. Rusty carried that forward into the living brain.
His work has since expanded beyond neurogenesis into how the genome shapes the nervous system over time. His lab explores mosaicism in the brain, the idea that our neurons are not genetically identical but subtly varied. The brain becomes not a static organ but a dynamic landscape, shaped by experience and by the restless choreography of DNA. It is a vision of the self that is fluid and intricate.
Photographing him in that office felt less like documenting a single scientist and more like tracing a lineage. Salk sought a vaccine that would protect children from paralysis. Rusty sought evidence that the adult brain was not condemned to decline. Both projects required a certain stubborn optimism. A belief that the body holds more possibility than we assume.
The weight of history was there, yes. But so was something lighter. A current of curiosity that refuses to settle. In Rusty Gage’s presence, you feel that science is not a monument. It is a conversation, still unfolding, with the ocean as witness.
NIDCR and NCCIH researchers developed an innovative strategy for linking two powerful but disconnected approaches for classifying neurons: single cell RNA-sequencing, which defines neurons according to the expression of hundreds of genes, and in vivo functional imaging, which characterizes groups of neurons according to their activity.
Learn more: www.nccih.nih.gov/research/research-results/new-insights-...
EXPLORE, EXPERIENCE AND WONDER
Activities to stimulate, inspire and amuse your little grey cells....
Art and Science on the Brain
Wonder Street Fair 7-9 April 2013
Barbican Centre, London
Festival of Neuroscience - BNA 2013
A unique experience with outstanding speakers presenting the latest developments in research into the brain and CNS organised by British Neuroscience Association and supported by Wellcome Trust
apart perhaps from a meteor crashing into the frozen pond, i don't know what creates these -- there were several of them there.
I made this cake for my friend and lab mate Andy's thesis defense. It was chocolate cake with a white chocolate cream cheese frosting. Yum!
Des p'tits neurones dans les cerveaux
Qui disparaissent de jours en jours
Dans les p'tits bois les p'tits discours
Des petits rois dans les basses cours
Des p'tits qui s'cachent des p'tits qu'on cache
Des p'tits qu'on joue à pile ou face
Des p'tits qui vont grossir les ventres
Des p'tits caissiers dans les carrefours
Des p'tits problèmes de récession
Des p'tits ministres dans les prisons
Des p'tits pour payer ton loyer
Des p'tits pour la communauté
Tapez tapez sur les claviers
Des pompes funèbres aux cours d'écoles
Faut voir comme les p'tits sont frigués
Y'a de la griffe sur les guiboles
Des p'tits insectes sur les fleurs
Des p'tits bugs dans le computer
Des p'tits pour l'eau des p'tits pour l'air
Des p'tits pour pourrir l'atmosphère
Marchez marchez les p'tits pinçons
Les petits rois les petits cons
Des p'tits pour vendre qui on est
A la criée sur les marchés
EXPLORE, EXPERIENCE AND WONDER
Activities to stimulate, inspire and amuse your little grey cells....
Art and Science on the Brain
Wonder Street Fair 7-9 April 2013
Barbican Centre, London
Festival of Neuroscience - BNA 2013
A unique experience with outstanding speakers presenting the latest developments in research into the brain and CNS organised by British Neuroscience Association and supported by Wellcome Trust