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Our engineers reduced the depth of the chase and work surface on our award-winning Sight-Line furniture to create a compact, space-saving command console with a smaller footprint that meets ergonomic standards.
• Insight consoles feature a high-density profile.
• Consoles contain a compact overall depth of 32″.
• Consoles are ideal if you’re challenged for space but need a fully functional control room console.
What was once a magnificent temple, now rubble. Thank you temple, for cleansing us through your burning.
B.E. candidate Max Fagin, far right, in reduced gravity. He and his Thayer design team created a dehumidification system for space flight for their ENGS 89/90: Engineering Design Methodology and Project Completion. The group was accepted to NASA's Microgravity University, where they tested their designs.
Photo by James Blair and Bill Stafford, courtesy of Max Fagin.
The last time we bought a new sofa was before the turn of the century (makes it sound older than 'before 2000').
This is an ex-display example with low bum mileage for half the cost of a new one. Sold!
The bit at the end reminds me of Carry On Cleopatra where she is being fed Grapes (by various male suitors). Can't beat a bit of Chaise Longuing around right?
We await delivery by a shiny green John Lewis truck...
Minister of Health Tyler Shandro spoke to reporters, from the Rockyview Surgical Centre in Calgary on Friday, March 5, 2021, about the province’s work to reduce the surgical backlog and reduce wait times.
Also in attendance were Dr. Francois Belanger, vice-president, Quality, and chief medical officer, Alberta Health Services and Dr. Mohamed Nanji, president and CEO, Surgical Centres Inc., and medical director, Rockyview Surgical Centre. (photography by Chris Schwarz/Government of Alberta)
USS Halsey (DDG-97) is an Arleigh Burke-class guided missile destroyer in the United States Navy. Halsey is named in honor of Fleet Admiral William Frederick "Bull" Halsey Jr.
USS Russell (DDG-59) is an Arleigh Burke-class destroyer in the United States Navy. She is the second ship of the USN to carry the name Russell and is named for Rear Admiral John Henry Russell and his son, Commandant of the Marine Corps John Henry Russell, Jr..
The Arleigh Burke class of guided missile destroyers (DDGs) is the United States Navy's first class of destroyer built around the Aegis Combat System and the SPY-1D multi-function passive electronically scanned array radar. The class is named for Admiral Arleigh Burke, the most famous American destroyer officer of World War II, and later Chief of Naval Operations. The class leader, USS Arleigh Burke, was commissioned during Admiral Burke's lifetime.
They were designed as multi-mission destroyers to fit the anti-aircraft warfare (AAW) role with their powerful Aegis radar and surface-to-air missiles; anti-submarine warfare (ASW), with their towed sonar array, anti-submarine rockets, and ASW helicopter; Anti-surface warfare (ASUW) with their Harpoon missile launcher; and strategic land strike role with their Tomahawk missiles. With upgrades to their to AN/SPY-1 phased radar systems and their associated missile payloads as part of the Aegis Ballistic Missile Defense System, members of this class have also begun to demonstrate some promise as mobile anti-ballistic missile and anti-satellite weaponry platforms.
Some versions of the class no longer have the towed sonar, or Harpoon missile launcher. Their hull and superstructure were designed to have a reduced radar cross section. The first ship of the class was commissioned on 4 July 1991. With the decommissioning of the last Spruance-class destroyer, USS Cushing, on 21 September 2005, the Arleigh Burke class ships became the U.S. Navy's only active destroyers; the class has the longest production run for any post-World War II U.S. Navy surface combatant. Besides the 62 vessels of this class (comprising 21 of Flight I, 7 of Flight II and 34 of Flight IIA) in service by 2013, up to a further 42 (of Flight III) have been envisaged.
(Text Wikipedia)
At extreme slow speeds, the spin of a record player is reduced to a glacial crawl, the music to seismic rumbling. A beat may last a minute, and the tiny slices of silence between them become ambient voids. On each day of the Festival a different record was played, from Ravel to The Sex Pistols to Ornette Coleman, slowed down to the length of the gallery opening hours. With this work Finer continues his interest in long-durational processes and extremes of scale.
Biography
Jem Finer is a UK-based artist, musician and composer. Since studying computer science in the 1970s, he has worked in a variety of fields, including photography, film, music and installation. His 1000-year long musical composition, Longplayer, represents a convergence of many of his concerns, particularly those relating to systems, long-durational processes and extremes of scale in both time and space.
Among his other works is Score For a Hole In the Ground, a permanent, self-sustaining musical installation in a forest in Kent which relies only on gravity and the elements to be audible. Between 2003 and 2005 he was artist in residence in the Astrophysics Department of Oxford University, making a number of works including two sculptural observatories, Landscope and The Centre of the Universe. Recent work, focusing on his interest in long-term sustainability and the reconfiguring of older technologies, includes Spiegelei, a 360-degree spherical camera obscura.
Credit
Curated and produced by AV Festival.
Automatic Thermoplastic Convex Applicator
W-TPVS Thermoplastic Applicator Profile is self-propelled convex thermoplastic applicator to mark vibration lines. Rib lines makes the drivers feel more obvious and then slow down. So this noise line becomes popular allover the world to reduce traffic accidents.
Details About Automatic Thermoplastic Convex Applicator
Vibration lines makes the drivers feel more obvious and then slow down. So this convex line becomes more and more widely used all around the world. Our designed W-TPVS automatic convex road marking machine can mark both raised lines and flat lines. In order to reduce traffic accidents, the highways edge lines, the entrance ramps, especially the deceleration zones nearby school, the blind roads, the edge lines of city streets, stops lines, etc. have been marked with convex lines.
The main spare parts of W-TPVS selfpropelled thermoplastic profile applicator are imported from Europe and America, To ensure pretty lines, operate easily, more durable. This configuration is much higher than other similar machine. It can mark both raised lines and flat lines, so you can use it as self-propelled thermoplastic applicator.
Road Marking Width:
1) Pneumatic Convex Line Marking Shoe Size:
10/15/20/30/45/50/60cm (4/6/8/12/18/24 inch) marking shoes optional, other special size also can be customized.
2) Adjustable Glass Beads Dispenser Size:
20 cm (10/15/20 cm adjustable)
45 cm (30/40/45 cm adjustable)
Advantages:
1. Imported Siemens computer control system, more stable, user-friendly.Digital display, easy to adjust the length and spacing of raised lines.
2. Imported Honda gasoline engine, high quality.
3. US imported Danfoss stepless speed change system, auto-moving forward and backward easily.
4. Italy imported solenoid valve and pneumatic components, high temperature resistance, less likely to break down.
5. Japan imported Omron encoder, Taiwan’s air compressor, to make spraying pressure more stable.
6. It can mark basic line and raising line at the same time.
7. The pattern and other size can be customized according to customers’ drawings.
8. Pneumatic vibration line shoe use high-quality imported alloy through special precision machining, high temperature resistance, anti-deformation, no leakage of paint, more durable. Flexible structure design, makes lines pretty, edges neat, thickness uniform.
9. One size glass bead dispenser can be adjusted in three sizes to save purchase costs.
10.Natural rubber wheels are wear and heat resistant.
ZHENJIANG RAYS TRAFFIC TECH CO., LTD.
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MTA Chair & CEO Janno Lieber announces the release of Reduced Fare OMNY cards on Friday, Dec 13, 2024 at the Stone Street Customer Service Center.
(Marc A. Hermann / MTA)
www.msn.com/en-us/money/markets/fda-lays-out-annual-covid...
FDA Lays Out Annual Covid Shot Plan Similar to Flu
(Bloomberg) -- Americans are about to get a clearer idea of how often they’ll roll up their sleeves for Covid-19 shots when advisers to US regulators meet Thursday to discuss an immunization schedule that looks more like the one used for flu.
The plan would have health officials meet each June to review which strains of the virus should be included in Covid shots to be deployed no later than September of the same year, according to documents released by the US Food and Drug Administration ahead of the Jan. 26 meeting.
Experts from around the world convene annually to make predictions about which flu strains will dominate during the upcoming season and, thus, should be targeted by shots. The FDA is looking for a similar coordinated effort to take place at least as often for Covid shots, one of several changes the agency hopes might help simplify the immunization process and encourage more Americans to stay up to date.
Waning immunity from vaccinations and the emergence of new variants every few months has led regulators to recommend variant-targeted boosters, a tactic that so far has been unpopular among Americans and has even split some health experts on costs and benefits. Just weeks after rolling out the updated BA.4 and BA.5 boosters in September, new mutations were rampant. Now, even as the US sees the rise of an immune-evasive variant called XBB.1.5, booster uptake is hovering at about 15%.
“Although the use of the bivalent mRNA boosters is supported by the available evidence, their deployment has been associated with significant implementation complexities,” the FDA said. Switching to one composition for both primary shots and boosters will help streamline the process, according to the agency documents.
Evidence suggests that immunity from prior exposure to the virus along with vaccination will provide enough protection so that most people will need one annual Covid booster, according to the documents. However, young children who might not have been previously exposed and people who are at higher risk for severe disease may need two yearly shots, the FDA said.
“An annual vaccine would be ideal because people would remember, they can do it with other vaccinations like flu and it can last,” Albert Bourla, chief executive officer of Covid vaccine-maker Pfizer Inc., said Jan. 18 in an interview with Bloomberg.
The FDA is still concerned about evasion of vaccine-induced immunity by mutants of the fast-spreading omicron strain, according to the documents. That warrants continued surveillance of variants and also monitoring of the protection previous vaccines provide against new strains.
Pfizer and Moderna Inc. are both working on next-generation vaccines that hold up against mutations and provide longer-lasting protection, but it’s unlikely those will be ready to go into arms anytime soon.
www.news-medical.net/news/20230123/SARS-CoV-2-Omicron-XBB...
SARS-CoV-2 Omicron XBB.1.5, CA.3.1, and CH.1.1 exhibit remarkable antibody resistance
In a recent study posted to bioRxiv* preprint server, researchers at Ohio State University examined the degree of neutralizing antibody (nAb) evasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB.1.5, CA.3.1, and CH.1.1 subvariants.
Several subvariants have emerged from SARS-CoV-2 Omicron, some showing relatively higher immune evasion, threatening vaccination efficacy. The BQ.1.1 sub-variant was the most prevalent following months of BA.5 predominance in the United States. Nonetheless, it is being quickly replaced by XBB.1.5. The XBB lineage was first detected in India as a recombinant of BA.2.75 and BA.2.10.1.1. Its emergence was alarming since it contained numerous mutations with established immune escape characteristics.
The effectiveness of monoclonal antibodies (mAbs), mono- or bivalent vaccines, and infection-induced immunity were reduced against XBB. The XBB lineage acquired two additional substitutions in the spike, resulting in XBB.1 and XBB.1.5 subvariants, and their impact remains unknown. In addition, the CA.3.1 and CH.1.1 subvariants of Omicron have been notable lately, as they carry the L452R substitution in the spike, previously discovered in the Delta and Omicron BA.4/5 variants.
The study and findings
In the present study, researchers evaluated the spike protein biology of emergent SARS-CoV-2 Omicron subvariants XBB.1.5, CA.3.1, and CH.1.1. First, they assessed the infectivity of spike-pseudotyped lentiviruses in HEK293T-ACE2 cells expressing human angiotensin-converting enzyme 2 (ACE2) and Calu-3 cell line. XBB.1 and XBB.1.5 had higher infectivity, with nearly two-fold increased titers than SARS-CoV-2 D614G in HEK293T-ACE2 cells.
XBB subvariants’ infectivity was not significantly different from that of D614G in this cell line. By contrast, CA.3.1 and CH.1.1 subvariants had nearly 2.5-fold lower infectivity than D614G in Calu-3. Next, the team tested neutralization of these emergent subvariants by sera from 14 healthcare workers (HCWs) boosted with a bivalent vaccine after two-to-four doses of monovalent mRNA vaccine.
Sera were obtained after a median of 66 days post-bivalent vaccination. CA.3.1, CH.1.1, and XBB.1.5 subvariants showed strong resistance to neutralization by sera relative to BA.4/5, with 4.6 to 17.7 times lower nAb titers than BA.4/5. Interestingly, XBB.1.5 had slightly higher nAb titers than its parent lineage (XBB).
Of note, BQ.1.1 showed higher neutralization resistance than any of the XBB subvariants, with 12.8 lower nAb titers than BA.4/5. The CA.3.1 and CH.1.1 subvariants displayed much higher resistance to neutralization by bivalent sera. Next, the neutralization experiments were repeated using sera from HCWs vaccinated thrice with monovalent mRNA vaccines.
Samples were obtained after 2-13 weeks post-vaccination. The mean nAb titers of triple-vaccinated sera against SARS-CoV-2 D614 and Omicron (BA.2 and BA.4/5) were up to 5.6-fold lower than those of bivalent sera. nAb titers were markedly reduced for CA.3.1, CH.1.1, and XBB.1.5 subvariants. Overall, the trends of triple-vaccinated sera in neutralizing subvariants were comparable to those of bivalent sera.
In addition, the team examined the neutralization resistance of subvariants to sera from individuals infected with BA.4/5. They observed potent and near-complete neutralization resistance for CA.3.1, CH.1.1, and XBB.1.1 subvariants, with 2.6 to 4.1-fold lower nAb titers than BA.4/5. Furthermore, the researchers determined fusogenicity, surface expression, and processing of spike proteins of the subvariants.
Reduced syncytia formation was evident for all subvariants relative to D614G. XBB.1 and XBB.1.5 showed no differences in spike fusogenicity compared to XBB. The efficiency of syncytia formation of CA.3.1 and CH.1.1 was lower than BA.2.75.2. XBB subvariants, BQ.1.1, and BA.2.75.2 exhibited higher spike processing than D614G. There were no differences in spike processing for CA.3.1 and CH.1.1 subvariants relative to the parental BA.2.75.2.
Finally, homology modeling of XBB lineage spikes complexed with ACE2 or nAbs was performed. The P486 residue in XBB.1.5 was more hydrophobic than the S486 residue in XBB/XBB.1, resulting in favorable interactions with residues in ACE2, which allows better receptor utilization. The residue 486 is a hotspot for class I nAb recognition, and mutations at this site in XBB subvariants completely abolish interactions with the therapeutic mAb, AZD8895. Mutations at K444 and L452 residues found in CA.3.1 and CH.1.1 also affect interactions with class II nAbs.
Conclusions
Taken together, the findings suggested that bivalent mRNA vaccines induce up to eight times higher nAbs than monovalent vaccines. XBB subvariants, CA.3.1 and CH.1.1, exhibited almost complete escape from neutralization by triple-vaccinated or BA.4/5 infection sera. Moreover, XBB.1.5 did not show enhanced immune evasion relative to BQ.1.1. CA.3.1 and CH.1.1 subvariants consistently showed higher resistance to neutralization than XBB subvariants, warranting continued surveillance and further analyses.
"SUMMER 2017 DAYLIFE" at The Pool Harrah's Atlantic City Saturday July 22, 2017
The Pool After Dark inside Harrah's Resort Atlantic City, NJ | Celebrating a birthday, bachelor, or bachelorette party? For FREE or Reduced Admission, VIP, or Bottle Service to Atlantic City's top nightlife destination, get on the nightclub guest list at www.gocoastalac.com.
My hair feels great even after over 6 weeks without ANY hair products including shampoo!
Blogged here: mushroomvillagers
See my version of the recipe attached to this photo set (www.flickr.com/photos/jjldickinson/sets/72157617605443361/). (Hint: click "See more," near the top of the screen.)
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Noise reduced first, and then color neutralized, and brightened Lauren's face selectively using adjustment layers and layer masks. The SOOC has a different feel and mood compared to the processed version.
If the light in the room behind me was brighter, the below could have been done.
My project is about my process through getting a breast reduction. I had large breasts since the 8th grade and at some point it was easier for people to know my chest than know my face. I stood out for it when all I wanted to do was blend in. In my piece, I used only a palette knife to control the paint because there is very little control much like how I felt throughout this process. I went over parts with colored pencil and ink to tighten it up. There are faces and skulls staring at the figure while the figure is faceless representing how it feels to not have your face be the first thing people notice. Throughout the piece, there are phrases people have said to me throughout the process that are somewhat hidden and somewhat in plain sight. I have included what people have said to me through the complications I have had with the reduction. Even as I am typing, I am developing hives from the medication I’m on. So my piece is messy and emotional and dark even though I used a lot of color. In life, there is vibrant light and hope but it is also extremely messy at times too.
This reduced-resolution photo has been released under the Creative Commons cc-by-sa 2.0 (generic) licence. Please credit this photo Michele Ahin and specify the licence that this photo is licenced under.
If you would like to use this photo under a different licence, or at a higher resolution please contact me for additional information.
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Red Cedar Park near Frandor in Lansing, MI shows the very intimate relationship between agriculture and commercial industries in the Lansing area.
They took down the forms and packaged-up everything — even the 2x4s — for reuse elsewhere.
Very cool.
Recent find. Almost dumpster diving. Someone put this out on their curb for the scrap metal recyclers -- looks like it was only used once - almost brand new. So I replaced my existing smoker (similar model, but about 16 years old and used so much it was rusting out), and left my own -- bought for $5 from a neighbor at a garage sale long ago -- out on the curb for the next guy.
This weekly Thursday meet during the summer is based at the sea front in the sea side resort of Weston Super Mare, North Somerset, UK.
It is organised by the Riders Branch of the British legion, all bike donate £1 to enter and all proceeds go the charity The Poppy Appeal.
Images can be obtained for a donation of £5 per image, the full image will then be e-mailed to you.
Either send donation via paypal stating the images wanted to bikenightphotos@btinternet.com or send a e-mail to bikenightphotos@btinternet.com with your request and a paypal invoice will be e-mailed to you allowing you to make a secure donation via debit/credit card.
All proceeds will go to the charity being supported by the event The Poppy Appeal
For further assistance about these images e-mail bikenightphotos@btinternet.com
Show your support for the event and donate for any photos you use, full size images are 3888 X 2592
Please note the images put onto this site are reduced in quality/ size.
Further Information
The Riders Branch of the Royal British Legion
Membership open to all who have a love of motorcycling and are in agreement with the aims of the British Legion
Weston Bike Night Website