View allAll Photos Tagged evolution
Cornwall commercials Fodaf and Daf and Foden. The Foden badged wreckers have equipment remounted from predessors. The Daf unit is for the tri axle trailer
This is a resin kit which came complete but in very sad condition. The original paint finish hadn't taken too well leaving a rather pock-marked surface which needed a large amount of preparation.
The interior was even more sad and needed a lot of TLC before it could be refinished.
A satisfying result, finished in Iwan Jones' usual colours.
418 has been a bit of a back-and-forth bus between Carousel and Thames Travel of late, but is now on permanent duties back at Carousel on the 'red' half of route 1 between High Wycombe and Chesham Grammar School.
Unfortunately the branding hasn't been best designed, and the red aspects (including the word 'red' above the o of one and the outlines of the orange circles) can't be seen on the overall red colour of the bus!
Route One has had a new ticket introduced in the last week or so, and is continually proving that partnership between two operators is not only possible but a reality, despite the drawbacks.
Carousel Buses
MAN 14.240 / MCV Evolution
418, AE59AWH
Primeiro da linha dos cromados da Eliana que uso e eu amei!
Super fácil de passar, ótimo pra limpar, a cor é lindo. Só amor hahaha
Cumpriu super bem a vontade de verdinho + brilhinhos que eu tava ^^
Com certeza vou usar todos os outros da coleção.
Foram:
-1 camada de base Marchetti com colágeno e elastina
-2 camadas de Evolution
-1 camada de extra brilho Ideal
Variation of a text-prompt generation in AI Deep Dream. The text contained the word GIGER.
The option of Text Prompt is a new feature on Deep Dream.
trying a text prompt from a different image with this image from may painting EVOLUTION.
Évolution du châssis Hanomag-Henschel, racheté en 1971.
Surnommé Harburger
4 cylindres diesel Mercedes 1998cm3 60ch Traction avant
``Free software'' is a matter of liberty, not price. To understand the concept, you should think of ``free'' as in ``free speech,'' not as in ``free beer.''
Free software is a matter of the users' freedom to run, copy, distribute, study, change and improve the software. More precisely, it refers to four kinds of freedom, for the users of the software:
* The freedom to run the program, for any purpose (freedom 0).
* The freedom to study how the program works, and adapt it to your needs (freedom 1). Access to the source code is a precondition for this.
* The freedom to redistribute copies so you can help your neighbor (freedom 2).
* The freedom to improve the program, and release your improvements to the public, so that the whole community benefits (freedom 3). Access to the source code is a precondition for this.
--taken from www.gnu.org/philosophy/free-sw.html - The Free Software Definition
Just watched Celestial's 500 drone swarm perform "Evolution" at the Bristol cricket ground. Amazing watching the 15 min swarm performance.
Hand held phone shot.
If you ever get the opportunity to see their show I can recommend it.
Dass die Evolution des Menschen noch nicht vorbei ist, liegt so ziemlich auf der Hand. Dass Karl-Heinz die Krone der Schöpfung darstellt, will jetzt wohl auch keiner mehr abstreiten.
Karl-Heinz auf frame-less.com hier und hier
Conclusion: Fasting and chemotherapy can work miracles. If you are on chemotherapy, fast three days before chemotherapy and one day after. I am not a doctor.
I recently wrote about one possible reason for the evolution of cancer, as a way to euthanase old-age palaeolithic persons who do not undergo periods of starvation, and are likely therefore to have been free-loading on the charity of their peers. In short I hypothesised that cancer may be a natural granny dumping mechanism.
But that got me to thinking about an even more puzzling evolutionary phenomena: why are there old people at all?
The average lifespan of palaeolithic peoples was about 33 years, which is just as it should be from a straightforward evolutionary perspective. If they started breeding at puberty then your average palaeolith would have had time to raise a few children and then die.
The strange thing is however that then, as till quite modern times, it was the high childhood death rate that suppressed average longevity. If a palaeolithic person reached puberty they lived on average into their mid fifties, way past the menopause and optimal male breeding potential. Further, with the agricultural revolution only a few thousand years ago, biblical and modern humans have palaeolithic bodies -- we have had time to evolve lactose tolerance and little else -- with the potential to live at least three score years and ten and four score if strong (Psalm 90).
Even if older palaeolithic persons were undergoing periods of near starvation and were not free-loading, they would have been consuming food which otherwise may have been gathered by their reproducing peers. So, why did evolution allow such grannies and grandfathers to exist at all? We could easily have evolved to self-destruct at 40. To a palaeolithic society living at the calorific brink of annihilation, the existence of post-breeding-age individuals would seem to be a tremendous calorific waste.
One can think of various 'nice' evolutionary-favoured tasks that post-reproduction-aged palaeolithic people could have performed, such as child minding or as a source of wisdom. I propose a task more tragic: older persons evolved as to function as in vivo experiments, commonly called 'guinea pigs'.
In any hunter gather society -- go out into the woods and try it today -- there would have been a lot of lean times. There would be very few apples, but a vast number of species of berries, bark, and beetles (and that is just the b's) with varying degrees of food value, nutrients, calories and toxicity. When (hunter) gatherers were lucky they found known fruits and roots to fulfil their dietary needs, but they were continually on the brink, regularly going without food, and faced with risky choices of culinary behaviour. "I have not eaten in a week. Do I try these berries or not? Do I give them to my children?"
Herein lies the great evolutionary value of the existence or granny and grandfather aged people like me. "Wait a minute son. Don't eat that. Don't give it to the little one. Let me try it. I will tell you in a day!" (When I think of all my ancestors that surely must have done this it makes me cry.) Societies which contained such individuals would continually increase the variety of gathered food sources and only lose the occasional non-breeding human guinea pig.
I reach this conclusion bearing in mind the miraculous research being carried out NOW on the synergy between chemotherapy and short term starvation in the treatment of cancer. The graph above left (Shi et al., 2012) shows tumour size in mice xenografted with human skin cancer. Cisplatin (CDDP), the most common chemotherapeutic drug, shows negligible effect in reducing tumour size. Short Term Starvation (STS) has a significant but small effect. Short term starvation combined with Cisplatin chemotherapy creates a synergy which seems nothing short of miraculous. 60% percent of the cancerous mice went into remission whereas no or negligible mice went into remission in the other two conditions. The same paper (ibid) also shows similar results, in vitro, with lung cancers.
Dr Valter Longo, the pioneer whose research on fasting lead to the discovery of this chemo-fasting synergy (e.g. Raffaghello, Safdie, Bianchi, Dorff, Fontana, & Longo 2010; Lee, & Longo, 2011), argues that fasting causes ordinary cells to go into hibernation mode, whereas cancer cells keep demanding more food. If in that period of starvation one consumes, or is injected with a toxin, then it is only cancerous cells that are killed. If one keeps fasting for about a day after the consumption or injection of the toxin, until the toxin has left ones system, then the toxin hardly effects normal cells at all.
This synergy between chemotherapy and no-calorie consumption suggests an explanation for both the existence of cancer, and the existence of old people. Old people get cancer. But many of them may be able to cure their own cancer if they undergo regular periods of fasting combined with the consumption of toxins. In modern society this experience is one that perhaps only cancer patients will undergo in the form of chemotherapy but in a (hunter) gathering palaeolithic society it would have experience that would regularly and necessarily have been faced. Going through that starvation plus toxin experience and coming out the other side, or not ("no, don't eat that...urk"), would have been evolutionarily favoured. So evolution worked out a way to create such individuals with that propensity: it created individuals that have a self destruct mechanism that is cured by starvation and toxin consumption. Palaeolithic societies that evolved to have older non-breeding individuals
-- Guinea Pig People (GPPs) -- to do the toxin tasting would have been able to gather and consume more food, breed more and continue the species. And here we are, thanks to all our GPPs.
In conclusion, it seems to me, a non-doctor, from limited research, fasting and chemotherapy can work miracles. If you are on chemotherapy, consult with your oncologist and consider fasting three days before chemotherapy and one day after, because it may cure your cancer, and makes perfect evolutionary sense.
Graph above: Figure 3A and 3B from Shi et al., 2012
Bibliography
Shi, Y., Felley-Bosco, E., Marti, T. M., Orlowski, K., Pruschy, M., & Stahel, R. A. (2012). Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin. BMC cancer, 12(1), 1.
bmccancer.biomedcentral.com/articles/10.1186/1471-2407-12...
Lee, C., & Longo, V. D. (2011). Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients. Oncogene, 30(30), 3305-3316.
Nowell, P. C. (1976). The Clonal Evolution of Tumor Cell Populations. Science, 194(4260), 23-28.
Raffaghello, L., Safdie, F., Bianchi, G., Dorff, T., Fontana, L., & Longo, V. D. (2010). Fasting and differential chemotherapy protection in patients. Cell Cycle, 9(22), 4474-4476.
The theory above - post breeding age persons are guinea pigs - is a little similar to the 'disposable soma' theory of the evolution of ageing at a societal rather than cellular level.
rspb.royalsocietypublishing.org/content/205/1161/531.short
"Organisms that do not age are essentially in a steady state in which chronologically young and old individuals are physiologically the same. In this situation the synthesis of macromolecules must be sufficiently accurate to prevent error feedback and the development of lethal 'error catastrophes'. This involves the expenditure of energy, which is required for both kinetic proof-reading and other accuracy promoting devices. It may be selectively advantageous for higher organisms to adopt an energy saving strategy of reduced accuracy in somatic cells." (Kirkwood, Holliday, 1979)
Somatic cells are non-reproductive cells.
These non reproducing cells are argued to be disposable to facilitate greater "proof reading" and prevent "error catastrophes" in the reproducing cells. I am suggesting above that somatic people (non reproducing people) are there, and yet disposable, there to be disposed of, to facilitate "proof reading" (toxin tasting - "reduced accuracy" in diet) and prevent error catastrophes in the non-somatic, reproductive population.
Relatedly
Peto's paradox (there is no correlation between animal size and cancer rate)
www.ncbi.nlm.nih.gov/pmc/articles/PMC3060950/
The assumption that there should be a correlation seems to be based on the assumption that cancer is a random occurrence in cells, so the more of them the greater the chance of cancer, as opposed to a more deliberate, non-random self destruct mechanism proposed here. Cancer is not random. It is a deliberate way of killing old people who do not fast be guinea pigs.
The BR Sealink sister ships Hengist and Horsa were long associated with the Folkestone-Boulogne route across the channel.
Here we see Horsa approaching Folkestone in 1975, when 3 years old. The Sealink design evolution from previous ferries is clear.
It's a great pity Folkestone is no longer used as a Cross-Channel port, it might alleviate some of the pressures on Dover.
Horsa was sold to Greek owners in 1992 and operated until 2012/3. In 2014 ship was arrested - financial difficulties and non-payment of crew for 6 months.
IMO 7205075
Built 1972 Arsenal de Brest, France
5,109 gt
Believed to be scrapped.
Scanned Instamatic Slide
1975