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Here is the first screenshot of my new flickr app : 365 project
A simple and intuitive way to show your own 365 project in a calendar style, take a look : 365.statsr.net
You can find the app in the Flickr app garden : www.flickr.com/services/apps/72157625784913627/
Object that have been treated with gamma irradiation. Museum of Brazilian and African Art, Sao Paulo, Brazil.
Photo Credit: Louise Potterton / IAEA
STROBIST:
One TTL flash, tethered via an TTL cable (10 meters, for Canon, from Yongnuo).
I tried two new light formers here:
1. Traveller8: not my cup of tea (spot too small, light too hard, needs a lot of tape for fixation -- the rubber band does not hold the tool on my flash)
2. Lastolite Mini brolly, 50 cm diameter: works, the shot above was shot with that tool
www.amazon.de/gp/product/B004TB0NGM/ref=oh_details_o01_s0...
But any other brolly could do the same or better...
An example for a larger brolly, which can be collapsed and which I like better:
www.amazon.de/gp/product/B0077HMXKO/ref=oh_details_o00_s0...
-
And if I really go on a journey I use a white microbrella (for the rain) with some gaffer tape (for the flash). :-()
www.source-werbeartikel.com/Microbrella+Mini+Taschenschir...
Application tracking spreadsheet, file management, stenciled envelope, photo corners, golden paper clips, 11 pages, just to apply for jobs?! Jeez.
"For fuck's sake, I know you're there...."
*CLICK* "H-hello?"
"S'me, Arnie. I need your help."
"Oh, really?... well, that makes, two of us."
"Wait, what? Shit, hold on--Kevin! Don't touch my briefcase! My shit's in there!"
"Jerrick, look, it's really complicated--"
"I can handle complicated just fine. Alot the shit I deal with is---KEVIN! Goddammit!--complicated."
"Well, what do you want anyway?"
"Need me to test any other PA gizmos for you? I'll be your test dummy for pay. MMA is down for a bit for me, so I need something else for my daylife---KEVIN, I WILL TAKE YOU TO MY FUCKING SHED!!!"
"The hell are you yelling about?"
"I'll tell you some other time. Hell, you'll probably meet him sometime. Anyway, anything I can do for you?"
"S-sure. I don't wanna say it on the phone. Meet me at the Armory or something tomorrow at 12 PM. I'll be out front."
"Something up Arnie? You sound fucked up. Arnie? Hey, Arnie!"
.............
"Sonuva bitch hung up on me! The hell's up with the secrecy anyway?... I mean---KEVIN!!! HOW THE FUCK DID YOU OPEN THAT?!? NO!! I HAVEN'T PAYED THOSE TICKETS OFF YET YOU CURLY-TAILED ASSHOLE!!!"
Application Polyester Armé Liège
APAL was originally a Belgian company that built lightweight sports cars based on VW Beetle floorpans. During the early 1960s they experimented with a special high-spec version of their coupe – it was fitted with Porsche 356 running gear including engine, transaxle, brakes, wheels, seats, instrumentation, and interior trim.
Classic Days 2013
Schloss Dyck
Jüchen - Germany
Augustus 2013
Application tracking spreadsheet, file management, stenciled envelope, photo corners, golden paper clips, 11 pages, just to apply for jobs?! Jeez.
Application tracking spreadsheet, file management, stenciled envelope, photo corners, golden paper clips, 11 pages, just to apply for jobs?! Jeez.
Application tracking spreadsheet, file management, stenciled envelope, photo corners, golden paper clips, 11 pages, just to apply for jobs?! Jeez.
This is a shot of an old version of Anxiety, a dashboard widget running through Amnesty Singles that works as a simple to do list. However, I've since abandoned this version, in favor of a sleeker 100% cocoa application, which syncs with iCal and Mail; pictures of the newer version can be found in my flickr photos.
Écrit sur un scrabble : application
Réutilisation libre contre un simple lien vers www.tyseo.net (licence CC BY 2.0)
Today is the last day our 2019/2020 Little Gallery application is online! All applications must be filled out and submitted to the gallery by March 31st. Good luck! degrazia.org/exhibitions/little-gallery/
Avaya IP Office Customer Call Reporter provides the supervisor with an at-a-glance Dashboard view of the selected goals and statistics most important for their business to manage and improve customer service.
Image source: Queensland State Archives Item ID ITM1102501 Expo 88 opening day crowds outside the Australia Pavilion, Brisbane.
World Expositions (or Exhibitions) become increasingly popular after the 1851 Great Exhibition in London, but their frequency, and the standard of their facilities, was not regulated until after the 1928 Paris Convention on International Expositions. The Bureau International des Expositions (BIE) was established in 1931 to administer the Convention. Under BIE rules there are two types of international exposition: the Universal/Category A/General Exposition, and the International/Category B/Special Exposition. The former involves broad themes, and participants design their own pavilions from the ground up, based on the theme.
The International Exposition, which has a narrower theme, is much cheaper to host, and is usually limited to one branch of human endeavour. Participants rent prefabricated pavilions from the host country's committee. Brisbane's Expo 88 was an International Exposition, with the theme "Leisure in the Age of Technology". Most of the structures built on exposition sites are intended to be temporary, but some sites have become parks, incorporating surviving exposition elements, including the sites of Montreal 1967, Seville 1992, Taejon 1993, and Lisbon 1998. Some structures have gone on to become landmarks in their own right, such as the Royal Exhibition Building (Melbourne 1880), the Eiffel Tower (Paris 1889), and the Space Needle (Seattle 1962).
The first bid to bring an exposition to Brisbane in 1988 began with James Maccormick , the architect who had designed the Australian pavilions at Montreal 1967, Osaka 1970, and Spokane 1974. The Brisbane Chamber of Commerce was converted to the idea, and lobbied the Queensland State Government during 1977. However, the Queensland Government was worried about the cost of a Universal Exposition, and was preoccupied with its bid for the 1982 Commonwealth Games. A second Queensland bid was made in 1981. The Australian Bicentennial Authority (ABA), under John Reid, wanted an Universal Exposition in Australia as part of Bicentennial in 1988, and the Federal Government was prepared to fund half of the cost of an exposition in Melbourne or Sydney. However, when these states turned the offer down in January 1981, Reid approached the Queensland Government with a proposal for a cheaper International Exposition. In late 1981 the State Cabinet funded a study that identified South Brisbane as the preferred site. The State Cabinet approved the study on 5 November 1981, on the condition that the Federal Government share the capital costs, but Prime Minister Malcolm Fraser rejected this notion in December 1981.
Queensland made two more attempts in 1982 for an International Exposition. Frank Moore, Chairman of the Queensland Tourist and Travel Corporation (QTTC), believed that private enterprise could fund the exposition, and that it would benefit Queensland's tourism. Queensland's Premier Joh Bjelke-Petersen asked Prime Minister Fraser to get the BIE to keep a slot open for Brisbane in 1988. Fraser was willing to support this proposal, so long as there was no Federal financial commitment. However, Queensland private enterprise was not forthcoming, and Bjelke-Petersen withdrew the proposal in April 1982. November of 1982 witnessed a renewed bid by the State Government. The State would lend money to a statutory authority, which would be tasked with buying and developing the land, and managing the exposition. Brisbane's application was sent to the December 1982 meeting of the BIE in Paris, and was approved in June 1983.
The Brisbane Exposition and South Bank Redevelopment Authority (BESBRA) was established in February 1984 by an Act of the Queensland Parliament. BESBRA was soon referred to in the media as the Expo 88 Authority, or the Expo Authority. Sir Llewellyn Edwards, the Deputy Premier, was appointed as Chairman. In April 1984 the Expo 88 Authority's general manager, Bob Minnikin, claimed that Expo 88 would require $180 million to produce, including resumptions and development, and $90 million to run. It was hoped that gate takings and sponsorship would cover the running costs, and that the development cost would be recouped through selling off the site after Expo 88. Only 13 hectares of the Expo 88 site was private land, with the remainder of the 40 hectares belonging to either the State Government or the Brisbane City Council. Nonetheless, the last resumption did not occur until October 1984, as the owner of the heritage-listed residence 'Collins Place' fought a running legal battle with the Expo 88 Authority.
Grey and Stanley Streets were closed to traffic in July 1985, and demolition work began. Construction of the pavilions started in January 1986. The concept of the Expo 88 architects, Bligh Maccormick 88, included eight large shade-canopies, to protect the public from the Queensland sun. Landscaping began in March 1987, and the Monorail, which would circle the site on a 2.3 kilometre long track, was commissioned in June of that year. By January 1988, $90 million of the $136.8 million construction budget had been spent, and 7.8 million visitors were expected.
During 1987 developers had been asked to present their proposals for Southbank's redevelopment after Expo 88. In February 1988 the State Government announced that the redevelopment plan of the River City 2000 Consortium had been accepted. The Consortium, headed by Sir Frank Moore of the QTTC, had visions of a World Trade Centre on an island, and a casino. However, by early 1988 there was a growing call in the media for more of the site to be turned into public parkland. During March and April 1988 the National Trust protested the River City 2000 Consortium's scheme to move Collins Place, the Plough Inn, and the Allgas Building, three heritage listed buildings, to a historic village. Premier Mike Ahern eventually gave reassurances that this would not happen.
Expo 88 ran for seven days a week, between the hours of 10am-10pm, for six months. Between its opening on 30 April, attended by Queen Elizabeth II, and 30 October 1988, the Expo attracted 15,760,447 visitors, the majority of these being Australians. Most of the international visitors were Japanese, but 100,000 came from the United Kingdom and Europe, with 150,000 visitors from the United States. A total of 36 nations, two international organisations, 14 state and regional governments, and 34 corporations had exhibits.
The pavilions were mostly plain, modular, and temporary. However, the Nepalese Peace Pagoda is a distinctive building, and was easily noticed as the public came through the Vulture Street entrance to Expo 88. The Association to Preserve Asian Culture (APAC) commissioned the Peace Pagoda, which was built by 160 craftsmen of the Kathmandu Valley over two years, before being assembled in Brisbane. It is one of only three such temples outside Nepal, the others being at Munich and Osaka. Nepal has a long history of intricate woodcarving on buildings, and the Peace Pagoda was an attempt to showcase this skill to the world. The two small timber pavilions in front of the Peace Pagoda sold yoghurt lati, samosas, orange juice and lemon tea. Artisans demonstrated their crafts inside the ground floor of the Pagoda, and people could drink their tea and watch the Expo crowds from the teahouse on the first floor. The nearby Nepalese pavilion showcased traditional costumes, climbing dress, photographs, and artefacts.
Expo 88 was a turning point for Queensland's culture and economy, especially in Brisbane. On 30 May 1983 Joh Bjelke-Petersen had noted that if Brisbane's bid were successful, it would focus the world's spotlight on Queensland. Sir Frank Moore believed that the key to developing a major tourist industry in Queensland was a series of hallmark events, including the 1982 Commonwealth Games, which would focus attention on Queensland far better than any advertising campaign. Expo 88 was also intended to start Brisbane on a modernisation process, and towards becoming a 'global' city. The urban renewal of South Brisbane was just one aspect. In April 1984 Sir Llew stated that Queensland would never be the same again after Expo 88, and Brisbane would develop an image as a centre of trade, culture and entertainment. In April 1988 the Courier Mail claimed that Expo 88 was "bridging the yawning gap from a hayseed State to an urbane, international future". Sir Llew also claimed in April 1988 that the aim was for Expo 88 to be a catalyst for a change in lifestyle. Queenslanders had experienced extended opening hours and outdoor café dining, and had liked it.
While the crowds enjoyed Expo 88, controversy continued regarding future plans for the site. There were calls for more public input on redevelopment plans. About 4.5 hectares of land between Stanley Street and the river belonged to the Brisbane City Council (BCC), as Clem Jones Park, and had been lent to the Expo 88 Authority. In June 1988 it was decided to restore this land as parkland, and the River City 2000 Consortium lost its Preferred Developer status.
Government plans for a South Bank Development Corporation were announced, and in July 1988 an interim committee, headed by Sir Llew, was formed to oversee redevelopment. Sir Llew noted in October 1988 that more public funding was necessary to increase the parkland component of the new Southbank, as the land had been earmarked for development to repay for the cost of Expo 88. The draft redevelopment plans released in November 1988 included 12 hectares of parkland. Public submissions on the plan suggested that people wanted to be able to return to the Expo 88 site, to a public facility that had a similar combination of food, art and nature.
At the end of Expo 88, the APAC had planned to sell the Nepalese Peace Pagoda, and it appeared likely that it would be moved to Japan. However, 90,000 people had signed a petition during Expo 88 to keep the Peace Pagoda in Brisbane, and in late 1988 the BCC offered to provide land for the Peace Pagoda, if the Federal Government would pay for its cost and maintenance. A "Save the Pagoda Campaign" was active by February 1989. Public donations eventually totalled $52,000, with $30,000 coming from one couple, who wanted to "give Brisbane something to remember from Expo 88". The BCC provided $50,000, and the Federal Government supplied $100,000. "The Friends of the Pagoda Committee" also raised funds to buy several items that had complemented the Peace Pagoda, including a brass statue of the deity of compassion, a bronze bell and carved stone frame, and a stone lingam.
The Southbank Development Corporation was set up February 1989, with Vic Pullar as the Chairman. Approximately $200 million had been spent on developing the Expo site, and this money had to be recouped. The South Bank Corporation Act was passed in May 1989, and the former Clem Jones Park area was transferred to the Southbank Corporation, which was tasked with managing a new parkland precinct. In June 1989 submissions were sought from five architectural firms, and in August the "Media Five" concept of a mixed residential, commercial, and parkland development was chosen. Under Media Five's plans, the Peace Pagoda would be moved to the northern part of the parklands. The Media Five Chairman, Desmond Brooks, also suggested that Collins Place, the Plough Inn and the Allgas Building be removed to a historic village, but Vic Pullar rejected this idea. However, when the Southbank Corporation's Draft Development Plan was released in November 1989, it proposed to only keep the facades of the historic buildings. After protests by the National Trust, the State Government overruled the Southbank Corporation.
The proposed redevelopment included a waterway through the park, and a large lagoon, which was later downsized. In March 1990 the Final Plan was presented, after public submissions, and site redevelopment started in July 1990. The official Southbank Parklands opening occurred on 20 June 1992. The Waterway was later filled in and replaced with the Energex Arbour, which was officially opened in March 2000.
The transfer of the Peace Pagoda to its current site started on 24 September 1991. The deity of compassion was moved from the first floor to a glass case on the ground floor, the sides of the ground floor were encased in glass, and a display case was added inside. Access to the first floor was sealed off. The two smaller pavilions were also transferred, but their service windows were locked up. Two lion statues and two elephant statues were also relocated. The building was originally designed to be demountable, but it is currently set in a ceramic tiled floor. The Peace Pagoda was one of the best-loved exhibits at Expo 88, as visitors were able to relax in it away from the bustle of the crowds. Today it is still popular, both with tourists, and those who go there to meditate and reflect.
Despite late entrants into the Exposition due to domestic political measures, World Expo 88 attracted some 100 pavilions, from 52 governments, of which 36 were from international-level, and numerous corporate participants. Major western and European nations were represented such as the United States, the Soviet Union (last representation at a World Exposition), France, West Germany (also last representation at a World Exposition), the United Kingdom, Canada, Spain and Greece, as well as major Asian countries such as Singapore, Thailand, Nepal, Pakistan, China, Japan, Sri Lanka, South Korea, Indonesia, and the Philippines, and amongst others. Close neighbouring countries, New Zealand and Papua New Guinea were also represented.
State-level and multi-lateral organisations included the six Australian states, the United Nations, the European Union, Vatican City, three American states (Hawaii, California and Alaska), one Japanese prefecture (sister state of Queensland, Saitama Prefecture), and one Japanese city (Brisbane's sister city Kobe City).
Corporate pavilions included IBM, Ford, Fujitsu, Queensland Newspapers, Australia Post, Cadbury Chocolate, Suncorp, and the Queensland Teachers Credit Union. NASA and Universal Studios hosted outdoor exhibits, with models of the space shuttle and Apollo program, as well as the car KITT from the TV series Knight Rider. Also having its own pavilion was the official Australian TV partner of the Expo, Network Ten, via its Queensland station TVQ, whose news studios were located there for public tours and during the Expo also switched channel frequencies in September (from channel 0 to channel 10) in line with the other state channels.
The most expensive pavilion was Japan (A$26 million), followed by the Queensland Pavilion (A$20 million) and the Australia Pavilion (A$18 million). The largest Pavilions were also Queensland,[6] followed by Australia then Japan.
High Definition TV received its Australian premiere at the Japan Pavilion, and the text-based Internet at the Swiss Pavilion. At the University pavilion the world's longest lab experiment was on display. The pitch drop experiment, which features tar pitch slowly dripping through a funnel at a rate of nine drops in 81 years, actually made an unseen drop while on display.
Students and young professionals discuss their projects during the 2019 Annual Earth Science Applications Showcase, Thursday, Aug. 1, 2019 at NASA Headquarters in Washington, DC. Every summer students and young professionals from NASA’s Applied Sciences’ DEVELOP National Program come to NASA Headquarters and present their research projects. DEVELOP is a training and development program where students work on Earth science research projects, mentored by science advisers from NASA and partner agencies, and extend research results to local communities. Photo Credit: (NASA/Joel Kowsky)
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startup-photos
Market Validation
Creating something that leads to deep customer engagement is really a struggle to complete. It's very easy to check the usability of the application, but how can you tell if there is a interest in it? The reply is running the prototype via a user test.
Based on research by Localytics, 22% of downloaded mobile phone application developer are just used once and 62% of application users are totally gone after 30 days. It’s important to possess a goal which goes past the mere quantity of downloads and maintains users by supplying continual value. When the application is downloaded, metrics like application engagement, usage, and lifelong value end up being the focus. Application prototyping will validate the merchandise with regards to the right market fit and consumer experience. This reduces costs before proceeding with further development.
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Patent US6506148 - Nervous system manipulation by electromagnetic fields from monitors
Publication number US6506148 B2
Publication type Grant
Application number US 09/872,528
Publication date Jan 14, 2003
Filing date Jun 1, 2001
Priority date Jun 1, 2001
Fee status Paid
Also published as US20020188164
Inventors Hendricus G. Loos
Original Assignee Hendricus G. Loos
Export Citation BiBTeX, EndNote, RefMan
Patent Citations (16), Non-Patent Citations (5), Referenced by (3), Classifications (6), Legal Events (3)
External Links: USPTO, USPTO Assignment, Espacenet
Nervous system manipulation by electromagnetic fields from monitors
US 6506148 B2
Abstract
Physiological effects have been observed in a human subject in response to stimulation of the skin with weak electromagnetic fields that are pulsed with certain frequencies near ½ Hz or 2.4 Hz, such as to excite a sensory resonance. Many computer monitors and TV tubes, when displaying pulsed images, emit pulsed electromagnetic fields of sufficient amplitudes to cause such excitation. It is therefore possible to manipulate the nervous system of a subject by pulsing images displayed on a nearby computer monitor or TV set. For the latter, the image pulsing may be imbedded in the program material, or it may be overlaid by modulating a video stream, either as an RF signal or as a video signal. The image displayed on a computer monitor may be pulsed effectively by a simple computer program. For certain monitors, pulsed electromagnetic fields capable of exciting sensory resonances in nearby subjects may be generated even as the displayed images are pulsed with subliminal intensity.
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Claims(14)
I claim:
1. A method for manipulating the nervous system of a subject located near a monitor, the monitor emitting an electromagnetic field when displaying an image by virtue of the physical display process, the subject having a sensory resonance frequency, the method comprising:
creating a video signal for displaying an image on the monitor, the image having an intensity;
modulating the video signal for pulsing the image intensity with a frequency in the range 0.1 Hz to 15 Hz; and
setting the pulse frequency to the resonance frequency.
2. A computer program for manipulating the nervous system of a subject located near a monitor, the monitor emitting an electromagnetic field when displaying an image by virtue of the physical display process, the subject having cutaneous nerves that fire spontaneously and have spiking patterns, the computer program comprising:
a display routine for displaying an image on the monitor, the image having an intensity;
a pulse routine for pulsing the image intensity with a frequency in the range 0.1 Hz to 15 Hz; and
a frequency routine that can be internally controlled by the subject, for setting the frequency;
whereby the emitted electromagnetic field is pulsed, the cutaneous nerves are exposed to the pulsed electromagnetic field, and the spiking patterns of the nerves acquire a frequency modulation.
3. The computer program of claim 2, wherein the pulsing has an amplitude and the program further comprises an amplitude routine for control of the amplitude by the subject.
4. The computer program of claim 2, wherein the pulse routine comprises:
a timing procedure for timing the pulsing; and
an extrapolation procedure for improving the accuracy of the timing procedure.
5. The computer program of claim 2, further comprising a variability routine for introducing variability in the pulsing.
6. Hardware means for manipulating the nervous system of a subject located near a monitor, the monitor being responsive to a video stream and emitting an electromagnetic field when displaying an image by virtue of the physical display process, the image having an intensity, the subject having cutaneous nerves that fire spontaneously and have spiking patterns, the hardware means comprising:
pulse generator for generating voltage pulses;
means, responsive to the voltage pulses, for modulating the video stream to pulse the image intensity;
whereby the emitted electromagnetic field is pulsed, the cutaneous nerves are exposed to the pulsed electromagnetic field, and the spiking patterns of the nerves acquire a frequency modulation.
7. The hardware means of claim 6, wherein the video stream is a composite video signal that has a pseudo-dc level, and the means for modulating the video stream comprise means for pulsing the pseudo-dc level.
8. The hardware means of claim 6, wherein the video stream is a television broadcast signal, and the means for modulating the video stream comprise means for frequency wobbling of the television broadcast signal.
9. The hardware means of claim 6, wherein the monitor has a brightness adjustment terminal, and the means for modulating the video stream comprise a connection from the pulse generator to the brightness adjustment terminal.
10. A source of video stream for manipulating the nervous system of a subject located near a monitor, the monitor emitting an electromagnetic field when displaying an image by virtue of the physical display process, the subject having cutaneous nerves that fire spontaneously and have spiking patterns, the source of video stream comprising:
means for defining an image on the monitor, the image having an intensity; and
means for subliminally pulsing the image intensity with a frequency in the range 0.1 Hz to 15 Hz;
whereby the emitted electromagnetic field is pulsed, the cutaneous nerves are exposed to the pulsed electromagnetic field, and the spiking patterns of the nerves acquire a frequency modulation.
11. The source of video stream of claim 10 wherein the source is a recording medium that has recorded data, and the means for subliminally pulsing the image intensity comprise an attribute of the recorded data.
12. The source of video stream of claim 10 wherein the source is a computer program, and the means for subliminally pulsing the image intensity comprise a pulse routine.
13. The source of video stream of claim 10 wherein the source is a recording of a physical scene, and the means for subliminally pulsing the image intensity comprise:
pulse generator for generating voltage pulses;
light source for illuminating the scene, the light source having a power level; and
modulation means, responsive to the voltage pulses, for pulsing the power level.
14. The source of video stream of claim 10, wherein the source is a DVD, the video stream comprises a luminance signal and a chrominance signal, and the means for subliminal pulsing of the image intensity comprise means for pulsing the luminance signal.
Description
BACKGROUND OF THE INVENTION
The invention relates to the stimulation of the human nervous system by an electromagnetic field applied externally to the body. A neurological effect of external electric fields has been mentioned by Wiener (1958), in a discussion of the bunching of brain waves through nonlinear interactions. The electric field was arranged to provide “a direct electrical driving of the brain”. Wiener describes the field as set up by a 10 Hz alternating voltage of 400 V applied in a room between ceiling and ground. Brennan (1992) describes in U.S. Pat. No. 5,169,380 an apparatus for alleviating disruptions in circadian rythms of a mammal, in which an alternating electric field is applied across the head of the subject by two electrodes placed a short distance from the skin.
A device involving a field electrode as well as a contact electrode is the “Graham Potentializer” mentioned by Hutchison (1991). This relaxation device uses motion, light and sound as well as an alternating electric field applied mainly to the head. The contact electrode is a metal bar in Ohmic contact with the bare feet of the subject, and the field electrode is a hemispherical metal headpiece placed several inches from the subject's head.
In these three electric stimulation methods the external electric field is applied predominantly to the head, so that electric currents are induced in the brain in the physical manner governed by electrodynamics. Such currents can be largely avoided by applying the field not to the head, but rather to skin areas away from the head. Certain cutaneous receptors may then be stimulated and they would provide a signal input into the brain along the natural pathways of afferent nerves. It has been found that, indeed, physiological effects can be induced in this manner by very weak electric fields, if they are pulsed with a frequency near ½ Hz. The observed effects include ptosis of the eyelids, relaxation, drowziness, the feeling of pressure at a centered spot on the lower edge of the brow, seeing moving patterns of dark purple and greenish yellow with the eyes closed, a tonic smile, a tense feeling in the stomach, sudden loose stool, and sexual excitement, depending on the precise frequency used, and the skin area to which the field is applied. The sharp frequency dependence suggests involvement of a resonance mechanism.
It has been found that the resonance can be excited not only by externally applied pulsed electric fields, as discussed in U.S. Pat. Nos. 5,782,874, 5,899,922, 6,081,744, and 6,167,304, but also by pulsed magnetic fields, as described in U.S. Pat. Nos. 5,935,054 and 6,238,333, by weak heat pulses applied to the skin, as discussed in U.S. Pat. Nos. 5,800,481 and 6,091,994, and by subliminal acoustic pulses, as described in U.S. Pat. No. 6,017,302. Since the resonance is excited through sensory pathways, it is called a sensory resonance. In addition to the resonance near ½ Hz, a sensory resonance has been found near 2.4 Hz. The latter is characterized by the slowing of certain cortical processes, as discussed in the '481, '922, '302, '744, '944, and '304 patents.
The excitation of sensory resonances through weak heat pulses applied to the skin provides a clue about what is going on neurologically. Cutaneous temperature-sensing receptors are known to fire spontaneously. These nerves spike somewhat randomly around an average rate that depends on skin temperature. Weak heat pulses delivered to the skin in periodic fashion will therefore cause a slight frequency modulation (fm) in the spike patterns generated by the nerves. Since stimulation through other sensory modalities results in similar physiological effects, it is believed that frequency modulation of spontaneous afferent neural spiking patterns occurs there as well.
It is instructive to apply this notion to the stimulation by weak electric field pulses administered to the skin. The externally generated fields induce electric current pulses in the underlying tissue, but the current density is much too small for firing an otherwise quiescent nerve. However, in experiments with adapting stretch receptors of the crayfish, Terzuolo and Bullock (1956) have observed that very small electric fields can suffice for modulating the firing of already active nerves. Such a modulation may occur in the electric field stimulation under discussion.
Further understanding may be gained by considering the electric charges that accumulate on the skin as a result of the induced tissue currents. Ignoring thermodynamics, one would expect the accumulated polarization charges to be confined strictly to the outer surface of the skin. But charge density is caused by a slight excess in positive or negative ions, and thermal motion distributes the ions through a thin layer. This implies that the externally applied electric field actually penetrates a short distance into the tissue, instead of stopping abruptly at the outer skin surface. In this manner a considerable fraction of the applied field may be brought to bear on some cutaneous nerve endings, so that a slight modulation of the type noted by Terzuolo and Bullock may indeed occur.
The mentioned physiological effects are observed only when the strength of the electric field on the skin lies in a certain range, called the effective intensity window. There also is a bulk effect, in that weaker fields suffice when the field is applied to a larger skin area. These effects are discussed in detail in the '922 patent.
Since the spontaneous spiking of the nerves is rather random and the frequency modulation induced by the pulsed field is very shallow, the signal to noise ratio (S/N) for the fm signal contained in the spike trains along the afferent nerves is so small as to make recovery of the fm signal from a single nerve fiber impossibile. But application of the field over a large skin area causes simultaneous stimulation of many cutaneous nerves, and the fm modulation is then coherent from nerve to nerve. Therefore, if the afferent signals are somehow summed in the brain, the fm modulations add while the spikes from different nerves mix and interlace. In this manner the S/N can be increased by appropriate neural processing. The matter is discussed in detail in the '874 patent. Another increase in sensitivity is due to involving a resonance mechanism, wherein considerable neural circuit oscillations can result from weak excitations.
An easily detectable physiological effect of an excited ½ Hz sensory resonance is ptosis of the eyelids. As discussed in the '922 patent, the ptosis test involves first closing the eyes about half way. Holding this eyelid position, the eyes are rolled upward, while giving up voluntary control of the eyelids. The eyelid position is then determined by the state of the autonomic nervous system. Furthermore, the pressure excerted on the eyeballs by the partially closed eyelids increases parasympathetic activity. The eyelid position thereby becomes somewhat labile, as manifested by a slight flutter. The labile state is sensitive to very small shifts in autonomic state. The ptosis influences the extent to which the pupil is hooded by the eyelid, and thus how much light is admitted to the eye. Hence, the depth of the ptosis is seen by the subject, and can be graded on a scale from 0 to 10.
In the initial stages of the excitation of the ½ Hz sensory resonance, a downward drift is detected in the ptosis frequency, defined as the stimulation frequency for which maximum ptosis is obtained. This drift is believed to be caused by changes in the chemical milieu of the resonating neural circuits. It is thought that the resonance causes perturbations of chemical concentrations somewhere in the brain, and that these perturbations spread by diffusion to nearby resonating circuits. This effect, called “chemical detuning”, can be so strong that ptosis is lost altogether when the stimulation frequency is kept constant in the initial stages of the excitation. Since the stimulation then falls somewhat out of tune, the resonance decreases in amplitude and chemical detuning eventually diminishes. This causes the ptosis frequency to shift back up, so that the stimulation is more in tune and the ptosis can develop again. As a result, for fixed stimulation frequencies in a certain range, the ptosis slowly cycles with a frequency of several minutes. The matter is discussed in the '302 patent.
The stimulation frequencies at which specific physiological effects occur depend somewhat on the autonomic nervous system state, and probably on the endocrine state as well.
Weak magnetic fields that are pulsed with a sensory resonance frequency can induce the same physiological effects as pulsed electric fields. Unlike the latter however, the magnetic fields penetrate biological tissue with nearly undiminished strength. Eddy currents in the tissue drive electric charges to the skin, where the charge distributions are subject to thermal smearing in much the same way as in electric field stimulation, so that the same physiological effects develop. Details are discussed in the '054 patent.
SUMMARY
Computer monotors and TV monitors can be made to emit weak low-frequency electromagnetic fields merely by pulsing the intensity of displayed images. Experiments have shown that the ½ Hz sensory resonance can be excited in this manner in a subject near the monitor. The 2.4 Hz sensory resonance can also be excited in this fashion. Hence, a TV monitor or computer monitor can be used to manipulate the nervous system of nearby people.
The implementations of the invention are adapted to the source of video stream that drives the monitor, be it a computer program, a TV broadcast, a video tape or a digital video disc (DVD).
For a computer monitor, the image pulses can be produced by a suitable computer program. The pulse frequency may be controlled through keyboard input, so that the subject can tune to an individual sensory resonance frequency. The pulse amplitude can be controlled as well in this manner. A program written in Visual Basic(R) is particularly suitable for use on computers that run the Windows 95(R) or Windows 98(R) operating system. The structure of such a program is described. Production of periodic pulses requires an accurate timing procedure. Such a procedure is constructed from the GetTimeCount function available in the Application Program Interface (API) of the Windows operating system, together with an extrapolation procedure that improves the timing accuracy.
Pulse variability can be introduced through software, for the purpose of thwarting habituation of the nervous system to the field stimulation, or when the precise resonance frequency is not known. The variability may be a pseudo-random variation within a narrow interval, or it can take the form of a frequency or amplitude sweep in time. The pulse variability may be under control of the subject.
The program that causes a monitor to display a pulsing image may be run on a remote computer that is connected to the user computer by a link; the latter may partly belong to a network, which may be the Internet.
For a TV monitor, the image pulsing may be inherent in the video stream as it flows from the video source, or else the stream may be modulated such as to overlay the pulsing. In the first case, a live TV broadcast can be arranged to have the feature imbedded simply by slightly pulsing the illumination of the scene that is being broadcast. This method can of course also be used in making movies and recording video tapes and DVDs.
Video tapes can be edited such as to overlay the pulsing by means of modulating hardware. A simple modulator is discussed wherein the luminance signal of composite video is pulsed without affecting the chroma signal. The same effect may be introduced at the consumer end, by modulating the video stream that is produced by the video source. A DVD can be edited through software, by introducing pulse-like variations in the digital RGB signals. Image intensity pulses can be overlaid onto the analog component video output of a DVD player by modulating the luminance signal component. Before entering the TV set, a television signal can be modulated such as to cause pulsing of the image intensity by means of a variable delay line that is connected to a pulse generator.
Certain monitors can emit electromagnetic field pulses that excite a sensory resonance in a nearby subject, through image pulses that are so weak as to be subliminal. This is unfortunate since it opens a way for mischievous application of the invention, whereby people are exposed unknowingly to manipulation of their nervous systems for someone else's purposes. Such application would be unethical and is of course not advocated. It is mentioned here in order to alert the public to the possibility of covert abuse that may occur while being online, or while watching TV, a video, or a DVD.
DESCRIPTION OF THE DRAWINGS
FIG. 1 illustrates the electromagnetic field that emanates from a monitor when the video signal is modulated such as to cause pulses in image intensity, and a nearby subject who is exposed to the field.
FIG. 2 shows a circuit for modulation of a composite video signal for the purpose of pulsing the image intensity.
FIG. 3 shows the circuit for a simple pulse generator.
FIG. 4 illustrates how a pulsed electromagnetic field can be generated with a computer monitor.
FIG. 5 shows a pulsed electromagnetic field that is generated by a television set through modulation of the RF signal input to the TV.
FIG. 6 outlines the structure of a computer program for producing a pulsed image.
FIG. 7 shows an extrapolation procedure introduced for improving timing accuracy of the program of FIG. 6.
FIG. 8 illustrates the action of the extrapolation procedure of FIG. 7.
FIG. 9 shows a subject exposed to a pulsed electromagnetic field emanating from a monitor which is responsive to a program running on a remote computer via a link that involves the Internet.
FIG. 10 shows the block diagram of a circuit for frequency wobbling of a TV signal for the purpose of pulsing the intensity of the image displayed on a TV monitor.
FIG. 11 depicts schematically a recording medium in the form of a video tape with recorded data, and the attribute of the signal that causes the intensity of the displayed image to be pulsed.
FIG. 12 illustrates how image pulsing can be embedded in a video signal by pulsing the illumination of the scene that is being recorded.
FIG. 13 shows a routine that introduces pulse variability into the computer program of FIG. 6.
FIG. 14 shows schematically how a CRT emits an electromagnetic field when the displayed image is pulsed.
FIG. 15 shows how the intensity of the image displayed on a monitor can be pulsed through the brightness control terminal of the monitor.
FIG. 16 illustrates the action of the polarization disc that serves as a model for grounded conductors in the back of a CRT screen.
FIG. 17 shows the circuit for overlaying image intensity pulses on a DVD output.
FIG. 18 shows measured data for pulsed electric fields emitted by two different CRT type monitors, and a comparison with theory.
DETAILED DESCRIPTION
Computer monitors and TV monitors emit electromagnetic fields. Part of the emission occurs at the low frequencies at which displayed images are changing. For instance, a rythmic pulsing of the intensity of an image causes electromagnetic field emission at the pulse frequency, with a strength proportional to the pulse amplitude. The field is briefly referred to as “screen emission”. In discussing this effect, any part or all what is displayed on the monitor screen is called an image. A monitor of the cathode ray tube (CRT) type has three electron beams, one for each of the basic colors red, green, and blue. The intensity of an image is here defined as
I=∫j dA, (1)
where the integral extends over the image, and
j=jr+jg+jb, (2)
jr, jg, and jb being the electric current densities in the red, green, and blue electron beams at the surface area dA of the image on the screen. The current densities are to be taken in the distributed electron beam model, where the discreteness of pixels and the raster motion of the beams are ignored, and the back of the monitor screen is thought to be irradiated by diffuse electron beams. The beam current densities are then functions of the coordinates x and y over the screen. The model is appropriate since we are interested in the electromagnetic field emision caused by image pulsing with the very low frequencies of sensory resonances, whereas the emissions with the much higher horizontal and vertical sweep frequencies are of no concern. For a CRT the intensity of an image is expressed in millamperes.
For a liquid crystal display (LCD), the current densities in the definition of image intensity are to be replaced by driving voltages, multiplied by the aperture ratio of the device. For an LCD, image intensities are thus expressed in volts.
It will be shown that for a CRT or LCD screen emissions are caused by fluctuations in image intensity. In composite video however, intensity as defined above is not a primary signal feature, but luminance Y is. For any pixel one has
Y=0.299R+0.587G+0.114B, (3)
where R, G, and B are the intensities of the pixel respectively in red, green and blue, normalized such as to range from 0 to 1. The definition (3) was provided by the Commission Internationale de l'Eclairage (CIE), in order to account for brightness differences at different colors, as perceived by the human visual system. In composite video the hue of the pixel is determined by the chroma signal or chrominance, which has the components R-Y and B-Y It follows that pulsing pixel luminance while keeping the hue fixed is equivalent to pulsing the pixel intensity, up to an amplitude factor. This fact will be relied upon when modulating a video stream such as to overlay image intensity pulses.
It turns out that the screen emission has a multipole expansion wherein both monopole and dipole contributions are proportional to the rate of change of the intensity I of (1). The higher order multipole contributions are proportional to the rate of change of moments of the current density j over the image, but since these contributions fall off rapidly with distance, they are not of practical importance in the present context. Pulsing the intensity of an image may involve different pulse amplitudes, frequencies, or phases for different parts of the image. Any or all of these features may be under subject control.
The question arises whether the screen emission can be strong enough to excite sensory resonances in people located at normal viewing distances from the monitor. This turns out to be the case, as shown by sensory resonance experiments and independently by measuring the strength of the emitted electric field pulses and comparing the results with the effective intensity window as explored in earlier work.
One-half Hertz sensory resonance experiments have been conducted with the subject positioned at least at normal viewing distance from a 15″ computer monitor that was driven by a computer program written in Visual Basic(R), version 6.0 (VB6). The program produces a pulsed image with uniform luminance and hue over the full screen, except for a few small control buttons and text boxes. In VB6, screen pixel colors are determined by integers R, G, and B, that range from 0 to 255, and set the contributions to the pixel color made by the basic colors red, green, and blue. For a CRT-type monitor, the pixel intensities for the primary colors may depend on the RGB values in a nonlinear manner that will be discussed. In the VB6 program the RGB values are modulated by small pulses ΔR, ΔG, ΔB, with a frequency that can be chosen by the subject or is swept in a predetermined manner. In the sensory resonance experiments mentioned above, the ratios ΔR/R, ΔG/G, and ΔB/B were always smaller than 0.02, so that the image pulses are quite weak. For certain frequencies near ½ Hz, the subject experienced physiological effects that are known to accompany the excitation of the ½ Hz sensory resonance as mentioned in the Background Section. Moreover, the measured field pulse amplitudes fall within the effective intensity window for the ½ Hz resonance, as explored in earlier experiments and discussed in the '874, '744, '922, and '304 patents. Other experiments have shown that the 2.4 Hz sensory resonance can be exited as well by screen emissions from monitors that display pulsed images.
These results confirm that, indeed, the nervous system of a subject can be manipulated through electromagnetic field pulses emitted by a nearby CRT or LCD monitor which displays images with pulsed intensity.
The various implementations of the invention are adapted to the different sources of video stream, such as video tape, DVD, a computer program, or a TV broadcast through free space or cable. In all of these implementations, the subject is exposed to the pulsed electromagnetic field that is generated by the monitor as the result of image intensity pulsing. Certain cutaneous nerves of the subject exhibit spontaneous spiking in patterns which, although rather random, contain sensory information at least in the form of average frequency. Some of these nerves have receptors that respond to the field stimulation by changing their average spiking frequency, so that the spiking patterns of these nerves acquire a frequency modulation, which is conveyed to the brain. The modulation can be particularly effective if it has a frequency at or near a sensory resonance frequency. Such frequencies are expected to lie in the range from 0.1 to 15 Hz.
An embodiment of the invention adapted to a VCR is shown in FIG. 1, where a subject 4 is exposed to a pulsed electric field 3 and a pulsed magnetic field 39 that are emitted by a monitor 2, labeled “MON”, as the result of pulsing the intensity of the displayed image. The image is here generated by a video casette recorder 1, labeled “VCR”, and the pulsing of the image intensity is obtained by modulating the composite video signal from the VCR output. This is done by a video modulator 5, labeled “VM”, which responds to the signal from the pulse generator 6, labeled “GEN”. The frequency and amplitude of the image pulses can be adjusted with the frequency control 7 and amplitude control 8. Frequency and amplitude adjustments can be made by the subject.
The circuit of the video modulator 5 of FIG. 1 is shown in FIG. 2, where the video amplifiers 11 and 12 process the composite video signal that enters at the input terminal 13. The level of the video signal is modulated slowly by injecting a small bias current at the inverting input 17 of the first amplifier 11. This current is caused by voltage pulses supplied at the modulation input 16, and can be adjusted through the potentiometer 15. Since the noninverting input of the amplifier is grounded, the inverting input 17 is kept essentially at ground potential, so that the bias current is is not influenced by the video signal. The inversion of the signal by the first amplifier 11 is undone by the second amplifier 12. The gains of the amplifiers are chosen such as to give a unity overall gain. A slowly varying current injected at the inverting input 17 causes a slow shift in the “pseudo-dc” level of the composite video signal, here defined as the short-term average of the signal. Since the pseudo-dc level of the chroma signal section determines the luminance, the latter is modulated by the injected current pulses. The chroma signal is not affected by the slow modulation of the pseudodc level, since that signal is determined by the amplitude and phase with respect to the color carrier which is locked to the color burst. The effect on the sync pulses and color bursts is of no consequence either if the injected current pulses are very small, as they are in practice. The modulated composite video signal, available at the output 14 in FIG. 2, will thus exhibit a modulated luminance, whereas the chroma signal is unchanged. In the light of the foregoing discussion about luminance and intensity, it follows that the modulator of FIG. 2 causes a pulsing of the image intensity I. It remains to give an example how the pulse signal at the modulation input 16 may be obtained. FIG. 3 shows a pulse generator that is suitable for this purpose, wherein the RC timer 21 (Intersil ICM7555) is hooked up for astable operation and produces a square wave voltage with a frequency that is determined by capacitor 22 and potentiometer 23. The timer 21 is powered by a battery 26, controlled by the switch 27. The square wave voltage at output 25 drives the LED 24, which may be used for monitoring of the pulse frequency, and also serves as power indicator. The pulse output may be rounded in ways that are well known in the art. In the setup of FIG. 1, the output of VCR 1 is connected to the video input 13 of FIG. 2, and the video output 14 is connected to the monitor 2 of FIG. 1.
In the preferred embodiment of the invention, the image intensity pulsing is caused by a computer program. As shown in FIG. 4, monitor 2, labeled “MON”, is connected to computer 31 labeled “COMPUTER”, which runs a program that produces an image on the monitor and causes the image intensity to be pulsed. The subject 4 can provide input to the computer through the keyboard 32 that is connected to the computer by the connection 33. This input may involve adjustments of the frequency or the amplitude or the variability of the image intensity pulses. In particular, the pulse frequency can be set to a sensory resonance frequency of the subject for the purpose of exciting the resonance.
The structure of a computer program for pulsing image intensity is shown in FIG. 6. The program may be written in Visual Basic(R) version 6.0 (VB6), which involves the graphics interface familiar from the Windows(R) operating system. The images appear as forms equipped with user controls such as command buttons and scroll bars, together with data displays such as text boxes. A compiled VB6 program is an executable file. When activated, the program declares variables and functions to be called from a dynamic link library (DLL) that is attached to the operating system; an initial form load is performed as well. The latter comprises setting the screen color as specified by integers R, G, and B in the range 0 to 255, as mentioned above. In FIG. 6, the initial setting of the screen color is labeled as 50. Another action of the form load routine is the computation 51 of the sine function at eight equally spaced points, I=0 to 7, around the unit circle. These values are needed when modulating the RGB numbers. Unfortunately, the sine function is distorted by the rounding to integer RGB values that occurs in the VB6 program. The image is chosen to fill as much of the screen area as possible, and it has spatially uniform luminance and hue.
The form appearing on the monitor displays a command button for starting and stopping the image pulsing, together with scroll bars 52 and 53 respectively for adjustment of the pulse frequency F and the pulse amplitude A. These pulses could be initiated by a system timer which is activated upon the elapse of a preset time interval. However, timers in VB6 are too inaccurate for the purpose of providing the eight RGB adjustment points in each pulse cycle. An improvement can be obtained by using the GetTickCount function that is available in the Application Program Interface (API) of Windows 95(R) and Windows 98(R). The GetTickCount function returns the system time that has elapsed since starting Windows, expressed in milliseconds. User activation of the start button 54 provides a tick count TN through request 55 and sets the timer interval to TT miliseconds, in step 56. TT was previously calculated in the frequency routine that is activated by changing the frequency, denoted as step 52.
Since VB6 is an event-driven program, the flow chart for the program falls into disjoint pieces. Upon setting the timer interval to TT in step 56, the timer runs in the background while the program may execute subroutines such as adjustment of pulse frequency or amplitude. Upon elapse of the timer interval TT, the timer subroutine 57 starts execution with request 58 for a tick count, and in 59 an upgrade is computed of the time TN for the next point at which the RGB values are to be adjusted. In step 59 the timer is turned off, to be reactivated later in step 67. Step 59 also resets the parameter CR which plays a role in the extrapolation procedure 61 and the condition 60. For ease of understanding at this point, it is best to pretend that the action of 61 is simply to get a tick count, and to consider the loop controled by condition 60 while keeping CR equal to zero. The loop would terminate when the tick count M reaches or exceeds the time TN for the next phase point, at which time the program should adjust the image intensity through steps 63-65. For now step 62 is to be ignored also, since it has to do with the actual extrapolation procedure 61. The increments to the screen colors R1, G1, and B1 at the new phase point are computed according to the sine function, applied with the amplitude A that was set by the user in step 53. The number I that labels the phase point is incremented by unity in step 65, but if this results in I=8 the value is reset to zero in 66. Finally, the timer is reactivated in step 67, initiating a new ⅛-cycle step in the periodic progression of RGB adjustments.
A program written in this way would exhibit a large jitter in the times at which the RGB values are changed. This is due to the lumpiness in the tick counts returned by the GetTickCount function. The lumpiness may be studied separately by running a simple loop with C=GetTickCount, followed by writing the result C to a file. Inspection shows that C has jumped every 14 or 15 milliseconds, between long stretches of constant values. Since for a ½ Hz image intensity modulation the ⅛-cycle phase points are 250 ms apart, the lumpiness of 14 or 15 ms in the tick count would cause considerable inaccuracy. The full extrapolation procedure 61 is introduced in order to diminish the jitter to acceptable levels. The procedure works by refining the heavy-line staircase function shown in FIG. 8, using the slope RR of a recent staircase step to accurately determine the loop count 89 at which the loop controled by 60 needs to be exited. Details of the extrapolation procedure are shown in FIG. 7 and illustrated in FIG. 8. The procedure starts at 70 with both flags off, and CR=0, because of the assignment in 59 or 62 in FIG. 6. A tick count M is obtained at 71, and the remaining time MR to the next phase point is computed in 72. Conditions 77 and 73 are not satisfied and therefore passed vertically in the flow chart, so that only the delay block 74 and the assignments 75 are executed. Condition 60 of FIG. 6 is checked and found to be satisfied, so that the extrapolation procedure is reentered. The process is repeated until the condition 73 is met when the remaining time MR jumps down through the 15 ms level, shown in FIG. 8 as the transition 83. The condition 73 then directs the logic flow to the assignments 76, in which the number DM labeled by 83 is computed, and FLG1 is set. The computation of DM is required for finding the slope RR of the straight-line element 85. One also needs the “Final LM” 86, which is the number of loops traversed from step 83 to the next downward step 84, here shown to cross the MR=0 axis. The final LM is determined after repeatedly incrementing LM through the side loop entered from the FLG1=1 condition 77, which is now satisfied since FLG1 was set in step 76. At the transition 84 the condition 78 is met, so that the assignments 79 are executed. This includes computation of the slope RR of the line element 85, setting FLG2, and resetting FLG1. From here on, the extrapolation procedure increments CR in steps of RR while skipping tick counts until condition 60 of FIG. 6 is violated, the loop is exited, and the RGB values are adjusted.
A delay block 74 is used in order to stretch the time required for traversing the extrapolation procedure. The block can be any computation intensive subroutine such as repeated calculations of tangent and arc tangent functions.
As shown in step 56 of FIG. 6, the timer interval TT is set to 4/10 of the time TA from one RGB adjustment point to the next. Since the timer runs in the background, this arrangement provides an opportunity for execution of other processes such as user adjustment of frequency or amplitude of the pulses.
The adjustment of the frequency and other pulse parameters of the image intensity modulation can be made internally, i.e., within the running program. Such internal control is to be distinguished from the external control provided, for instance, in screen savers. In the latter, the frequency of animation can be modified by the user, but only after having exited the screen saver program. Specifically, in Windows 95(R) or Windows 98(R), to change the animation frequency requires stopping the screen saver execution by moving the mouse, whereafter the frequency may be adjusted through the control panel. The requirement that the control be internal sets the present program apart from so-called banners as well.
The program may be run on a remote computer that is linked to the user computer, as illustrated in FIG. 9. Although the monitor 2, labeled “MON”, is connected to the computer 31′, labeled “COMPUTER”, the program that pulses the images on the monitor 2 runs on the remoter computer 90, labeled “REMOTE COMPUTER”, which is connected to computer 31′ through a link 91 which may in part belong to a network. The network may comprise the Internet 92.
The monitor of a television set emits an electromagnetic field in much the same way as a computer monitor. Hence, a TV may be used to produce screen emissions for the purpose of nervous system manipulation. FIG. 5 shows such an arrangement, where the pulsing of the image intensity is achieved by inducing a small slowly pulsing shift in the frequency of the RF signal that enters from the antenna. This process is here called “frequency wobbling” of the RF signal. In FM TV, a slight slow frequency wobble of the RF signal produces a pseudo-dc signal level fluctuation in the composite video signal, which in turn causes a slight intensity fluctuation of the image displayed on the monitor in the same manner as discussed above for the modulator of FIG. 2. The frequency wobbling is induced by the wobbler 44 of FIG. 5 labeled “RFM”, which is placed in the antenna line 43. The wobbler is driven by the pulse generator 6, labeled “GEN”. The subject can adjust the frequency and the amplitude of the wobble through the tuning control 7 and the amplitude control 41. FIG. 10 shows a block diagram of the frequency wobbler circuit that employs a variable delay line 94, labelled “VDL”. The delay is determined by the signal from pulse generator 6, labelled “GEN”. The frequency of the pulses can be adjusted with the tuning control 7. The amplitude of the pulses is determined by the unit 98, labelled “MD”, and can be adjusted with the amplitude control 41. Optionally, the input to the delay line may be routed through a preprocessor 93, labelled “PRP”, which may comprise a selective RF amplifier and down converter; a complimentary up conversion should then be performed on the delay line output by a postprocessor 95, labelled “POP”. The output 97 is to be connected to the antenna terminal of the TV set.
The action of the variable delay line 94 may be understood as follows. Let periodic pulses with period L be presented at the input. For a fixed delay the pulses would emerge at the output with the same period L. Actually, the time delay T is varied slowly, so that it increases approximately by LdT/dt between the emergence of consecutive pulses at the device output. The pulse period is thus increased approximately by
ΔL=LdT/dt. (4)
In terms of the frequency ∫, Eq. (4) implies approximately
Δ∫/∫=−dT/dt. (5)
For sinusoidal delay T(t) with amplitude b and frequency g, one has
Δ∫/∫=−2πgb cos (2πgt), (6)
which shows the frequency wobbling. The approximation is good for gb<<1, which is satisfied in practice. The relative frequency shift amplitude 2πgb that is required for effective image intensity pulses is very small compared to unity. For a pulse frequency g of the order of 1 Hz, the delay may have to be of the order of a millisecond. To accomodate such long delay values, the delay line may have to be implemented as a digital device. To do so is well within the present art. In that case it is natural to also choose digital implementations for the pulse generator 6 and the pulse amplitude controller 98, either as hardware or as software.
Pulse variability may be introduced for alleviating the need for precise tuning to a resonance frequency. This may be important when sensory resonance frequencies are not precisely known, because of the variation among individuals, or in order to cope with the frequency drift that results from chemical detuning that is discussed in the '874 patent. A field with suitably chosen pulse variability can then be more effective than a fixed frequency field that is out of tune. One may also control tremors and seizures, by interfering with the pathological oscillatory activity of neural circuits that occurs in these disorders. Electromagnetic fields with a pulse variability that results in a narrow spectrum of frequencies around the frequency of the pathological oscillatory activity may then evoke nerve signals that cause phase shifts which diminish or quench the oscillatory activity.
Pulse variability can be introduced as hardware in the manner described in the '304 patent. The variability may also be introduced in the computer program of FIG. 6, by setting FLG3 in step 68, and choosing the amplitude B of the frequency fluctuation. In the variability routine 46, shown in some detail in FIG. 13, FLG3 is detected in step 47, whereupon in steps 48 and 49 the pulse frequency F is modified pseudo randomly by a term proportional to B, every 4th cycle. Optionally, the amplitude of the image intensity pulsing may be modified as well, in similar fashion. Alternatively, the frequency and amplitude may be swept through an adjustable ramp, or according to any suitable schedule, in a manner known to those skilled in the art. The pulse variability may be applied to subliminal image intensity pulses.
When an image is displayed by a TV monitor in response to a TV broadcast, intensity pulses of the image may simply be imbedded in the program material. If the source of video signal is a recording medium, the means for pulsing the image intensity may comprise an attribute of recorded data. The pulsing may be subliminal. For the case of a video signal from a VCR, the pertinent data attribute is illustrated in FIG. 11, which shows a video signal record on part of a video tape 28. Depicted schematically are segments of the video signal in intervals belonging to lines in three image frames at different places along the tape. In each segment, the chroma signal 9 is shown, with its short-term average level 29 represented as a dashed line. The short-term average signal level, also called the pseudo-dc level, represents the luminance of the image pixels. Over each segment, the level is here constant because the image is for simplicity chosen as having a uniform luminance over the screen. However, the level is seen to vary from frame to frame, illustrating a luminance that pulses slowly over time. This is shown in the lower portion of the drawing, wherein the IRE level of the short-term chroma signal average is plotted versus time. The graph further shows a gradual decrease of pulse amplitude in time, illustrating that luminance pulse amplitude variations may also be an attribute of the recorded data on the video tape. As discussed, pulsing the luminance for fixed chrominance results in pulsing of the image intensity.
Data stream attributes that represent image intensity pulses on video tape or in TV signals may be created when producing a video rendition or making a moving picture of a scene, simply by pulsing the illumination of the scene. This is illustrated in FIG. 12, which shows a scene 19 that is recorded with a video camera 18, labelled “VR”. The scene is illuminated with a lamp 20, labelled “LAMP”, energized by an electric current through a cable 36. The current is modulated in pulsing fashion by a modulator 30, labeled “MOD”, which is driven by a pulse generator 6, labelled “GENERATOR”, that produces voltage pulses 35. Again, pulsing the luminance but not the chrominance amounts to pulsing the image intensity.
The brightness of monitors can usually be adjusted by a control, which may be addressable through a brightness adjustment terminal. If the control is of the analog type, the displayed image intensity may be pulsed as shown in FIG. 15, simply by a pulse generator 6, labeled “GEN”, that is connected to the brigthness adjustment terminal 88 of the monitor 2, labeled “MON”. Equivalent action can be provided for digital brightness controls, in ways that are well known in the art.
The analog component video signal from a DVD player may be modulated such as to overlay image intensity pulses in the manner illustrated in FIG. 17. Shown are a DVD player 102, labeled “DVD”, with analog component video output comprised of the luminance Y and chrominance C. The overlay is accomplished simply by shifting the luminance with a voltage pulse from generator 6, labeled “GENERATOR”. The generator output is applied to modulator 106, labeled “SHIFTER”. Since the luminance Y is pulsed without changing the chrominance C, the image intensity is pulsed. The frequency and amplitude of the image intensity pulses can be adjusted respectively with the tuner 7 and amplitude control 107. The modulator 105 has the same structure as the modulator of FIG. 2, and the pulse amplitude control 107 operates the potentiometer 15 of FIG. 2. The same procedure can be followed for editing a DVD such as to overlay image intensity pulses, by processing the modulated luminance signal through an analog-to-digital converter, and recording the resulting digital stream onto a DVD, after appropriate compression. Alternatively, the digital luminance data can be edited by electronic reading of the signal, decompression, altering the digital data by software, and recording the resulting digital signal after proper compression, all in a manner that is well known in the art.
The mechanism whereby a CRT-type monitor emits a pulsed electromagnetic field when pulsing the intensity of an image is illustrated in FIG. 14. The image is produced by an electron beam 10 which impinges upon the backside 88 of the screen, where the collisions excite phosphors that subsequently emit light. In the process, the electron beam deposits electrons 18 on the screen, and these electrons contribute to an electric field 3 labelled “E”. The electrons flow along the conductive backside 88 of the screen to the terminal 99 which is hooked up to the high-voltage supply 40, labelled “HV”. The circuit is completed by the ground connection of the supply, the video amplifier 87, labeled “VA”, and its connection to the cathodes of the CRT. The electron beams of the three electron guns are collectively shown as 10, and together the beams carry a current J. The electric current J flowing through the described circuit induces a magnetic field 39, labeled “B”. Actually, there are a multitude of circuits along which the electron beam current is returned to the CRT cathodes, since on a macroscopic scale the conductive back surface 88 of the screen provides a continuum of paths from the beam impact point to the high-voltage terminal 99. The magnetic fields induced by the currents along these paths partially cancel each other, and the resulting field depends on the location of the pixel that is addressed. Since the beams sweep over the screen through a raster of horizontal lines, the spectrum of the induced magnetic field contains strong peaks at the horizontal and vertical frequencies. However, the interest here is not in fields at those frequencies, but rather in emissions that result from an image pulsing with the very low frequencies appropriate to sensory resonances. For this purpose a diffuse electron current model suffices, in which the pixel discreteness and the raster motion of the electron beams are ignored, so that the beam current becomes diffuse and fills the cone subtended by the displayed image. The resulting low-frequency magnetic field depends on the temporal changes in the intensity distribution over the displayed image. Order-of-magnitude estimates show that the low-frequency magnetic field, although quite small, may be sufficient for the excitation of sensory resonances in subjects located at a normal viewing distance from the monitor.
The monitor also emits a low-frequency electric field at the image pulsing frequency. This field is due in part to the electrons 18 that are deposited on the screen by the electron beams 10. In the diffuse electron beam model, screen conditions are considered functions of the time t and of the Cartesian coordinates x and y over a flat CRT screen.
The screen electrons 18 that are dumped onto the back of the screen by the sum j(x,y,t) of the diffuse current distributions in the red, green, and blue electron beams cause a potential distribution V(x,y,t) which is influenced by the surface conductivity σ on the back of the screen and by capacitances. In the simple model where the screen has a capacitance distribution c(x,y) to ground and mutual capacitances between parts of the screen at different potentials are neglected, a potential distribution V(x,y,t) over the screen implies a surface charge density distribution
q=Vc(x,y), (7)
and gives rise to a current density vector along the screen,
j s=−σgrads V, (8)
where grads is the gradient along the screen surface. Conservation of electric charge implies
j=c{dot over (V)}−div s (σgrad s V), (9)
where the dot over the voltage denotes the time derivative, and divs is the divergence in the screen surface. The partial differential equation (9) requires a boundary condition for the solution V(x,y,t) to be unique. Such a condition is provided by setting the potential at the rim of the screen equal to the fixed anode voltage. This is a good approximation, since the resistance Rr between the screen rim and the anode terminal is chosen small in CRT design, in order to keep the voltage loss JRr to a minimum, and also to limit low-frequency emissions.
Something useful can be learned from special cases with simple solutions. As such, consider a circular CRT screen of radius R with uniform conductivity, showered in the back by a diffuse electron beam with a spatially uniform beam current density that is a constant plus a sinusoidal part with frequency ∫. Since the problem is linear, the voltage V due to the sinusoidal part of the beam current can be considered separately, with the boundary condition that V vanish at the rim of the circular screen. Eq. (9) then simplifies to
V″+V″/r−i2π∫cn V=−Jη/A, r≦R, (10)
where r is a radial coordinate along the screen with its derivative denoted by a prime, η=1/σ is the screen resistivity, A the screen area, J the sinusoidal part of the total beam current, and i=(−1), the imaginary unit. Our interest is in very low pulse frequencies ∫ that are suitable for excitation of sensory resonances. For those frequencies and for practical ranges for c and η, the dimensionless number 2π∫cAη is very much smaller than unity, so that it can be neglected in Eq. (10). The boundary value problem then has the simple solution V ( r ) = J η 4 π ( 1 - ( r / R ) 2 ) . ( 11 )
Figure US06506148-20030114-M00001
In deriving (11) we neglected the mutual capacitance between parts of the screen that are at different potentials. The resulting error in (10) is negligible for the same reason that the i2π∫cAη term in (10) can be neglected.
The potential distribution V(r) of (11) along the screen is of course accompanied by electric charges. The field lines emanating from these charges run mainly to conductors behind the screen that belong to the CRT structure and that are either grounded or connected to circuitry with a low impedance path to ground. In either case the mentioned conductors must be considered grounded in the analysis of charges and fields that result from the pulsed component J of the total electron beam current. The described electric field lines end up in electric charges that may be called polarization charges since they are the result of the polarization of the conductors and circuitry by the screen emission. To estimate the pulsed electric field, a model is chosen where the mentioned conductors are represented together as a grounded perfectly conductive disc of radius R, positioned a short distance δ behind the screen, as depicted in FIG. 16. Since the grounded conductive disc carries polarization charges, it is called the polarization disc. FIG. 16 shows the circular CRT screen 88 and the polarization disc 101, briefly called “plates”. For small distances δ, the capacitance density between the plates of opposite polarity is nearly equal to ε/δ, where ε is the permittivity of free space. The charge distributions on the screen and polarization disc are respectively εV(r)/δ+q0 and −εV(r)/δ+q0, where the εV(r)/δ terms denote opposing charge densities at the end of the dense field lines that run between the two plates. That the part q0 is needed as well will become clear in the sequel.
The charge distributions εV(r)/δ+q0 and −εV(r)/δ+q0 on the two plates have a dipole moment with the density D ( r ) = εV ( r ) = J ηε 4 π ( 1 - ( r / R ) 2 ) , ( 12 )
Figure US06506148-20030114-M00002
directed perpendicular to the screen. Note that the plate separation δ has dropped out. This means that the precise location of the polarization charges is not critical in the present model, and further that δ may be taken as small as desired. Taking δ to zero, one thus arrives at the mathematical model of pulsed dipoles distributed over the circular CRT screen. The field due to the charge distribution q0 will be calculated later.
The electric field induced by the distributed dipoles (12) can be calculated easily for points on the centerline of the screen, with the result E ( z ) = V ( 0 ) R { 2 ρ / R - R / ρ - 2 z / R } , ( 13 )
Figure US06506148-20030114-M00003
where V(0) is the pulse voltage (11) at the screen center, ρ the distance to the rim of the screen, and z the distance to the center of the screen. Note that V(0) pulses harmonically with frequency ∫, because in (11) the sinusoidal part J of the beam current varies in this manner.
The electric field (13) due to the dipole distribution causes a potential distribution V(r)/2 over the screen and a potential distribution of −V(r)/2 over the polarization disc, where V(r) is nonuniform as given by (11). But since the polarization disc is a perfect conductor it cannot support voltage gradients, and therefore cannot have the potential distribution −V(r)/2. Instead, the polarization disc is at ground potential. This is where the charge distribution q0(r) comes in; it must be such as to induce a potential distribution V(r)/2 over the polarization disc. Since the distance between polarization disc and screen vanishes in the mathematical model, the potential distribution V(r)/2 is induced over the screen as well. The total potential over the monitor screen thus becomes V(r) of (11), while the total potential distribution over the polarization disc becomes uniformly zero. Both these potential distributions are as physically required. The electric charges q0 are moved into position by polarization and are partly drawn from the earth through the ground connection of the CRT.
In our model the charge distribution q0 is located at the same place as the dipole distribution, viz., on the plane z=0 within the circle with radius R. At points on the center line of the screen, the electric field due to the monopole distribution q0 is calculated in the following manner. As discussed, the monopoles must be such that they cause a potential φ0 that is equal to V(r)/2 over the disc with radius R centered in the plane z=0. Although the charge distribution q0(r) is uniquely defined by this condition, it cannot be calculated easily in a straightforward manner. The difficulty is circumvented by using an intermediate result derived from Excercise 2 on page 191 of Kellogg (1953), where the charge distribution over a thin disc with uniform potential is given. By using this result one readily finds the potential φ*(z) on the axis of this disc as φ * ( z ) = 2 π V * β ( R 1 ) , ( 14 )
Figure US06506148-20030114-M00004
where β(R1) is the angle subtended by the disc radius R1, as viewed from the point z on the disc axis, and V* is the disc potential. The result is used here in an attempt to construct the potential φ0(z) for a disc with the nonuniform potential V(r)/2, by the ansatz of writing the field as due to a linear combination of abstract discs with various radii R1 and potentials, all centered in the plane z=0. In the ansatz the potential on the symmetry axis is written φ 0 ( z ) = α β ( R ) + b ∫ 0 R β ( R 1 ) W , ( 15 )
Figure US06506148-20030114-M00005
where W is chosen as the function 1−R1 2/R2, and the constants a and b are to be determined such that the potential over the plane z=0 is V(r)/2 for radii r ranging from 0 to R, with V(r) given by (11). Carrying out the integration in (15) gives
φ0(z)=αβ(R)−b{(1+z 2 /R 2)β(R)−|z|/R}. (16)
In order to find the potential over the disc r<R in the plane z=0, the function φ0(z) is expanded in powers of z/R for 0<z<R, whereafter the powers zn are replaced by rnPn(cosθ), where the Pn are Legendre polynomials, and (r,θ) are symmetric spherical coordinates centered at the screen center. This procedure amounts to a continuation of the potential from the z-axis into the half ball r0, in such a manner that the Laplace equation is satisfied. The method is discussed by Morse and Feshbach (1953). The “Laplace continuation” allows calculation of the potential φ0 along the surface of the disc r0, the parts (13) and (19) contribute about equally to the electric field over a practical range of distances z. When going behind the monitor where z is negative the monopole field flips sign so that the two parts nearly cancel each other, and the resulting field is very small. Therefore, in the back of the CRT, errors due to imperfections in the theory are relatively large. Moreover our model, which pretends that the polarization charges are all located on the polarization disc, fails to account for the electric field flux that escapes from the outer regions of the back of the screen to the earth or whatever conductors happen to be present in the vincinity of the CRT. This flaw has relatively more serious consequences in the back than in front of the monitor.
Screen emissions in front of a CRT can be cut dramatically by using a grounded conductive transparent shield that is placed over the screen or applied as a coating. Along the lines of our model, the shield amounts to a polarization disc in front of the screen, so that the latter is now sandwiched between to grounded discs. The screen has the pulsed potential distribution V(r) of (11), but no electric flux can escape. The model may be modified by choosing the polarization disc in the back somewhat smaller than the screen disc, by a fraction that serves as a free parameter. The fraction may then be determined from a fit to measured fields, by minimizing the relative standard deviation between experiment and theory.
In each of the electron beams of a CRT, the beam current is a nonlinear function of the driving voltage, i.e., the voltage between cathode and control grid. Since this function is needed in the normalization procedure, it was measured for the 15″ computer monitor that has been used in the ½ Hz sensory resonance experiments and the electric field measurements. Although the beam current density j can be determined, it is easier to measure the luminance, by reading a light meter that is brought right up to the monitor screen. With the RGB values in the VB6 program taken as the same integer K, the luminance of a uniform image is proportional to the image intensity I. The luminance of a uniform image was measured for various values of K. The results were fitted with
I=c 1 K γ, (20)
where c1 is a constant. The best fit, with 6.18% relative standard deviation, was obtained for γ=2.32.
Screen emissions also occur for liquid crystal displays (LCD). The pulsed electric fields may have considerable amplitude for LCDs that have their driving electrodes on opposite sides of the liquid crystal cell, for passive matrix as well as for active matrix design, such as thin film technology (TFT). For arrangements with in-plane switching (IPS) however, the driving electrodes are positioned in a single plane, so that the screen emission is very small. For arrangements other than IPS, the electric field is closely approximated by the frin
Stem cell therapy is an advanced and beneficial treatment for diabetes, numerous patients with diabetes have shown noticeable improvement, long-time remission and were able to enjoy a high quality of life after the therapy in SQ1 stem cell medical center.
The Beneficial Effects Of Stem Cell Therapy On Diabetes
Stem cell therapy can improve pancreatic islets function, hepatic glucose, and lipid metabolism while lowering blood sugar.
Clinical research and applications have shown that through stem cell therapy, about 65% of the patients are no longer dependent on insulin or oral drug to treat diabetes, and over 90% of patients reported reduced a dosage of insulin or oral drug or changed from insulin injection to oral drug. Collectively, stem cell therapy greatly diminished the onset and development of diabetes complications.
The era of clinical stem cell therapy for diabetes has come!
Reduction of diabetes medication intake
Maintenance of normal blood sugar levels
Restoration of the sensitivity of peripheral tissue to insulin and increase of insulin levels
Prevention and improvement of related diabetic foot symptoms
Reduction of hepatocyte lipid-related lesions
Improvement in the condition of the arterial walls and reduction of hyperinsulinemia and atherosclerosis
Prevention or reversion of certain complications of diabetes, such as erectile dysfunction and vision loss
Diabetes-Related Diseases That Stem Cell Therapy Can Treat
Type 1 diabetes
Type 2 diabetes
Stem cell therapy also can treat complications of diabetes including:
Diabetic foot: foot infections, ulcers, and deep layer tissue damage.
Diabetic retinopathy: it can cause blurred vision, decreased vision, and even blindness.
Diabetic cardiovascular and cerebrovascular diseases: it can cause a cerebral infarction, cerebral hemorrhage, vascular dementia, etc.
Diabetic neuropathy: it can cause numbness and tingle in hands and feet, orthostatic hypotension, vomiting, urinary, and fecal incontinence, etc.
Diabetic nephropathy(chronic renal failure): it can cause foamy urine, edema, and renal failure.
Capillary and macrovascular complications: diabetes can lead to narrowing of lower extremity arteries, coronary heart disease, stroke, etc.
In 2019, the famous US news magazine “TIME” listed diabetes treatment with stem cell therapy as one of the top 10 innovative medical inventions that will change the future. In the year 2021, Mass General Brigham selected the ground-breaking “stem cell therapies for Diabetes” as one of the Top 12 “Disruptive gene and cell therapy technologies”.
Learn More About Diabetes
Diabetes is a metabolic disorder disease characterized by hyperglycemia(high blood sugar), it is also the third-largest non-infectious chronic disease following cancer and cardiovascular disease. There are approximately 537 million diabetes patients in the world by the year 2021.
Clinically, there are three main types of diabetes: type 1, type 2, and gestational diabetes (diabetes while pregnant). The major incidence populations of type 1 diabetes are adolescents and children, it is recognized by the destruction of pancreatic β-cells which leads to insufficient insulin secretion and hyperglycemia. Type 2 diabetes is caused by genetic, and environmental factors and their interactions. Usually, it is characterized by malfunction of pancreatic β-cell and insulin resistance in cells. Gestational diabetes develops in pregnant women who have never had diabetes before. If you have gestational diabetes, your baby could be at higher risk for health problems. Your baby is more likely to have obesity as a child or teen, and more likely to develop type 2 diabetes later in life too.
Risk Factors For Type 2 Diabetes
Type 2 diabetes is believed to have a strong genetic link, meaning that it tends to run in families. If you have a parent, brother, or sister who has it, your chances rise.
You should ask your doctor about a diabetes test when you have any of the following risk factors:
High blood pressure.
High blood triglyceride (fat) levels. It's too high if it's over 150 milligrams per deciliter (mg/dL).
Low "good" cholesterol level. It's too low if it's less than 40 mg/dL.
Gestational diabetes or giving birth to a baby weighing more than 9 pounds.
Prediabetes. That means your blood sugar level is above normal, but you don't have the disease yet.
Heart disease.
High-fat and carbohydrate diet. This can sometimes be the result of food insecurity when you don’t have access to enough healthy food.
High alcohol intake.
Sedentary lifestyle.
Obesity or being overweight.
Polycystic ovary syndrome (PCOS).
Being of ethnicity that’s at higher risk: African Americans, Native Americans, Hispanic Americans, and Asian Americans are more likely to get type 2 diabetes than non-Hispanic whites.
You're over 45 years of age. Older age is a significant risk factor for type 2 diabetes. The risk of type 2 diabetes begins to rise significantly around age 45 and rises considerably after age 65.
You’ve had an organ transplant. After an organ transplant, you need to take drugs for the rest of your life so your body doesn’t reject the donor. organ. These drugs help organ transplants succeed, but many of them, such as tacrolimus (Astagraf, Prograf) or steroids, can cause diabetes or make it worse.
Clinical Symptoms Of Diabetes
Polyuia
Dry mouth and increased thirst
Strong appetite
Unexplained Weight loss
Fatigue
Obesity
Presence of glucose in urine
Presence of ketones in urine
Abnormal high amount of glycosylated hemoglobin (HbA1c) in serum
Glycated serum protein abnormality
Abnormal amount of insulin and c-peptide in serum
Dyslipidemia(unhealthy level of blood fat)
Stem Cell Therapy For Diabetes At SQ1
Stem cells used in the treatment of diabetes
SQ1 provides access to treatment that utilizes mesenchymal stem cells (MSCs) isolated from the cord blood, placenta, and/or peripheral blood of patients and embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs), into pancreatic endocrine lineages.
A combination MSCs and hESCs delivered via the intravenous route for 30 minutes at a delivery rate of 40 mL/hour to a final dose of 1 × 106 cells/kg of the patient's body weight.
The combination of cells and other treatment details are individual to the patient and is determined by genetically-programmed factors, individual to every human.
The therapeutic scope and efficacy of stem cell therapy for diabetes
A double infusion of hESCs+MSCs through either the intravenous route or the dorsal pancreatic artery route is performed for patients with type 2 Diabetes. The therapy exhibited term efficacy (7-9 months) in patients with type 2 diabetes for less than 10 years (the longest period of remission registered to date is 10 years and the shortest – 2 years) and a BMI <23 kg/m2 and improvement in hyperglycemia, reported blood glucose levels within the normal range.
Our results revealed reductions in the HbA1c and FBG levels during the first 3 months after administration in patients with type 2 Diabetes, deemed clinically significant because the reduction was maintained in a normal range at 12 months after administration.
Factors determining the efficacy of the treatment and remission term are individual and genetically driven.
Advantages Of Stem Cell Treatment For Diabetes
Traditional therapeutic methods, such as daily medication or injections of exogenous insulin, are the most common diabetes treatment, but their use is frequently associated with failure of glucose metabolism control, which leads to hyperglycemia episodes.
Stem cell therapy is a promising strategy for avoiding the problems associated with daily insulin injections. To maintain glucose homeostasis, this therapeutic method is expected to produce, store, and supply insulin. To completely cure diabetes, cell-based therapies aim to produce functional insulin-secreting cells.
Stem cell therapy
Conventional treatment
Curative Treatment or diseases management
The stem cell is a curative treatment for diabetes. Stem cell therapy is designed to rejuvenate the pancreas which helps the body to produce insulin naturally.
If given in the early stages, the dependency on medication and insulin can be reversed.
Insulin and medicine are used to control the amount of glucose in your blood. It is not a cure treatment it is used to control diabetes.
Slowly and gradually, people on medication move to insulin dependency.
Dosage
Stem cell therapy reduces the dosages of medication and insulin as the body starts producing insulin naturally.
If given in the early stages, the dependency on medication and insulin can be reversed.
Stem cell experts based on your current level of disease and other comorbidities will design a customized protocol and decide, the number of stem cells, source of stem cells, and cycles of stem cell therapy.
Patients who are on medication will observe a slow and gradual increase in dosages of medication.
At a certain point in time when medication is not able to manage the sugar levels, external insulin support will be required.
Patients who are on insulin support need to take insulin daily before consumption of food. The doses of insulin also increase with time.
Side-effects
No Side-effects as stem cells are our cells that are used to treat the disease and regenerate the pancreas to regain proper functioning.
Some of the common side-effects that medication and insulin can develop are upset stomach, skin rash or itching, weight gain, tiredness, and if not taken properly can even low blood sugar extremely.
Convenience
Stem cell therapy is performed by stem cell specialists which requires a special laboratory to process the stem cells and the medical set up to extract and inject the stem cell.
The therapy is going to be injection-based and needs to be performed in a hospital.
Medication that can be easily consumed.
Repeated and multiple small pricks for insulin injection for the patients who are currently on insulin.
The strict discipline to take medication or insulin on time as prescribed.
Longevity
Long-term effect and possibly curative treatment which removes the dependency on insulin and medication if taken in the early stage.
If taken in the later stages it reduces your dependency on medication and insulin. In a few cases, a repeat cycle may also be required.
Short-term effects.
Need to take insulin and medication daily as prescribed and the medication and effectiveness are for a few hours or a day.
The patient needs to take the medication and insulin lifetime.
End-stage
Stem cells are the basic building block of our body. The main functionality of stem cells is to regenerate the damaged cells and make copies of their own cells to repair the damaged cells.
Your own body is healing you and deferring the need for a transplant.
A pancreas transplant is the only treatment in the end stage.
There is a high probability that the kidney might also be damaged due to diabetes so in some cases both kidney and pancreas transplants would be required.
The availability of the donor and the waiting period can be a big reason for worry.
How Can Stem Cell Therapy For Diabetes Work
Stem cells were able to lower blood sugar levels and restore islet function in the following three ways:
Improvement of insulin resistance: stem cells will secret a variety of cytokines to improve the insulin resistance conditions in peripheral tissues and promote sugar intake by cells, thus reversing the hyperglycemia status in the body.
Promotion of regeneration of pancreatic islet β cells: Stem cells can reduce the progressive lesion to pancreatic islets from metabolic disorders in diabetes, at the same time can regenerate pancreatic β cells. In addition, stem cells can secret various cytokines to improve the microenvironment and induce the transformation of islet α cells to β cells. This process enables the in-situ regeneration of β cells and leads to the stabilization of blood sugar level.
Immunomodulation effect: stem cells can inhibit the T cell-mediated immune response against newly generated β cells and promote the repair and regeneration of pancreatic islets.
SQ1 Stem Cell Services
During the whole treatment process, we’ll provide complete and first-class medical services to you. And to ensure your treatment effect, you can consult your doctor any time after the treatment.
New/additional pictures from an old model.
With retro-camouflaged Valkyries popping up in official sourcebooks (like Su-27, U.S. Navy or Royal Navy derivates) and some national identity in mind, I wondered what a German Valkyrie would look like? Well, this here is the (quite flashy) result! The idea came when I recently got hands on the brand new WAVE Ma.K. 'Snake-Eye' kit - the box art shows the fighting suit with very special decorative markings: "tulip" wedges.
For those interested, here's an excursion about the story behind it:
The 'black tulip' markings have a real historic heritage from WWII. They had been the personal markings of German pilot ace Erich Hartmann on his Messerschmidt Bf-109 fighter machines. The characterstic markings were painted on the motor cowl, just behind the propeller spinner, which used to be black, too.
After the war (and 352 air combat victories!), when Germany began re-building its defensive forces under the pressure of the Cold War, Erich Hartmann returned from Russian imprisonment, joined German Luftwaffe's forces again and received in 1960 command over Germany's first jet fighter squadron, the JG 71 "Richthofen", which was initially equiped with CL-13 Mk. 6, Canadian-built F-86F-40 'Sabres'.
Consequently, besides the glamorous "Richthofen" name of the squadron, JG71's F-86 would sport the 'black tulip' trademark of their commander around their air intakes and on the fins, paired with bright red or yellow contrast fields. The tulips would, with the advent of the F-104G 'Starfighter' in the mid 60ies, disappear again, though.
But back to the little Valkyrie: The kit is actually a bastard. I did not have a single seater left in stock, so I bashed a VF-1D two-seater with the cockpit and wings of a single-seater Gerwalk kit. This caused little problem, since these kits have almost 100% matching 'interfaces'. The Gerwalk cockpit just differs slightly in proportions and lacks a landing gear compartment. The wings have no punches/adapters for weapons underneath, and the holes for the wings' sweeping mechanism are a bit larger than on the Fighter kits.
Beyond that, the Valkyrie was - as usual - built almost right out of the box, with typical minor details added to the exterior like some antennae, plus some interior things like a pilot figure and a HUD.
In oder to set this Valkyrie a bit apart from the anime versions, I gave it an "L" designation (for "Luftwaffe", the only plausible suffix I could find which was not occupied yet...). A scratch-built laser spot tracker (similar to the Pave Penny system) was mounted under the Valkyrie's front as part of a domestic KWS package ("Kampfwertsteigerung", a German term and abbreviation for military vehicle upgrades). This package also includes subtle details like passive radar sensors (fins, front, legs) and flare dispensers (legs), Small things, but they add some grit and differentiate it from standard anime models. The wings were left empty, in order not to compromise the wonderful lines and keep the kit's focus on its unique livery.
The basic paint scheme is typical for German jets like the F-4F, F-104G or Alpha Jet in the 1960-80 era. AFAIK, it was officially called "Norm '72", but it had the inofficial nickname of "Zitronenfalter" ("Brimstone Butterfly"). It already looks retro due to the angular design, but proves highly effective at medium heights over typical German countryside or over coast line areas. Today it would be sold as "fractal", but the design's origins reach back into the pre-WWII time.
The authentic colors of the Norm '72 scheme are RAL 6014 ("Gelboliv", a dark, brownish olive drab tone; Humbrol's 108 or Revell's 46 come close), RAL 7012 ("Basaltgrau", similar to the Bristish Dark Sea Grey or FS36118) for above and RAL 7001 for the undersides ("Silbergrau", a unique light grey with a metallic hue).
For the small Valkyrie kit , though, I settled for different, lighter shades, because the original tones are pretty murky and they'd rather conceal the wicked camouflage pattern. The Gelboliv became the much lighter 1711 from Testors (simple Olive drab, FS34087), and for the dark Basaltgrau, Humbrol's 27 (Matt Sea Grey) was used. The obscure undersides' RAL 7001 was simulated with a 1:1 mix of Humbrol's 11 and 34 (Silver and Flat White).
While the choice of tones was basically O.K., the olive drab turned out to be way too light after application. The contrast with Humbrol's 27 was weak, so Humbrol 108 would be recommended for a more authentic look, even though weathering would bleach the real colors. But, heck, we are doing anime here! Therefore, I left it as it was.
When the basic camouflage was done, though, I found that something was missing to round up the Valkyrie's look, due to the low contrast of the Zitronenfalter scheme's colors from above. As a visual trick, I simply added leading edges on the wings and fins in Humbrol 94 (Matt Brown Yellow) - this plausible detail clears up the machine's outlines but does not compromise the overall visual style.
The red squadron markings were painted with Humbrol 174 (Signal Red), a bright and yellowish red tone which came out almost orange in the proximity to the murky camouflage. The black tulip wedges were partly taken from a HobbyBoss Sabre's JG71 decal sheet in 1:72 and partly hand-painted in black, with white decal trims. I was surprised how these small details changed the total look of the machine!
A light wash with black ink in order to point out the surface engravings and a final coat of matt varnish (except for the nose, which is intentionally finished in high gloss like German F-4F Phantom's with the Norm '72 outfit) finished the job.
The typical German bort numbers in black with white outlines came from a spare decal set. The Valkyrie's shown registration 27+85 corresponds to German Luftwaffe's nomenklatura since 1968 (the Hartmann tulips are older, though), but is fictional. By current standards, numbers from 20+01 to 49+99 are reserved for front line fighters, with serials corresponding to types in service (and not to sqaudrons). 27+85 would have been a TF-104G Starfighter trainer at its time, but phased-out numbers have been knwon to be used again, so the bort number is plausible ;)
Overall I find this Valkyrie interpretation better than expected. At first I was afraid that the Zitronenfalter scheme would make it look boring. It IS retro, O.K., but the flashy, historic JG71 trims add that special touch and comic-likeness that make it IMO look plausible even for the Macross universe? It is amazing what you can make from these simple kits, and once more respect and awe for Kawamori Shoji's timeless design. So inspiring! ^^
This is a shot of an old version of Anxiety, a dashboard widget running through Amnesty Singles that works as a simple to do list. However, I've since abandoned this version, in favor of a sleeker 100% cocoa application, which syncs with iCal and Mail; pictures of the newer version can be found in my flickr photos.
LiveFurnish is revolutionary application that allows Furnishing & Furniture Retailers, Manufacturers and Wholesalers sell, showcase and customize their products and designs.
A Mobile & Tablet Application, LiveFurnish is for all types of furnishing, furniture, Tiles, Vinyls, Laminates, Curtains, Wall Papers, Cushions, Cloth Materials and many more.
3D Visualization: Enable retailers to interactively visualize one of the largest libraries of Furniture in 3D
...Or how to spend £8.5M of other people's money.
Its finished! woot! all submitted to the council and thank god that is all over now. Just have to build the thing now.
Vacuum Trucks Application Only Financing, Up To 250,000, Minimum Credit Score 650
Vacuum Truck Application only financing up to 250,000 is available for applicants with minimum 650 personal credit scores...
Additionally, the below requirements for vacuum truck financing are also desired.
Must be Biz minimum two years
The equipment must be at least 20,000
Equipment must be ten years or newer
Signed and dated application
Three months biz bank statements
Vendor invoice and conditon report
The types of qualified equipment include
Dump Trucks, Sewer Trucks, Day Cabs, Backhoes, lift equipment, bulldozer, chipper, compactors, cranes
drill rig, excavator, forklifts, motor grader, motor scraper, skid
steer loader, wheel loader, yard tractor etc
Give us a call at 800 760 6863 and get the details
According to the definition of the app by different authors with references as they were able to figure out the definition of the app in a different perspective.
Definition of App.
The app is a short word for an Application.
It's simply a software designed to work with mobile phones which are generated in computers for smartphones, Android, iPhone, iOS, desktop.
And as well as others wearable smart wristwatch that works with the app as we reckoned with the smart wristwatches of Pebble when is connected to Bluetooth with the app.
Who then is app creator?
As we briefly tell a short story about the app creator who initiated an AppSheet into Creative Arts Solution Foundation.
Since 2018, just to mention someone significant who has successfully come up with an application from AppSheet created by app creator for Creative Arts Solution Foundation on the 3rd - 14th of November 2018 by Olusola David, Ayibiowu (App creator)
This app is specially created by the app creator, Olusola David, Ayibiowu since 3rd & 14th of Nov 2018.
App Name:
Creative Arts Solution Foundation
Target Audience: Everyone, company, organization, foundation, NGOs, stakeholders, social media, visual arts, social platform, politics, donors, marketers, advertisers, Arts Exhibition, businesses as well as sales order online app.
Benefits: Everyone can edit, add, delete, create your own advertisement on this app within 5 Minutes or 45 Minutes.
Access to all features of the AppSheet in order to create an app for business and personal use, association, organization, and for positive influence in our society by creating awareness on particular ongoing programs, political events, products, online marketing to generate a lead. It also serves as a medium for effective and positive traffic sources to blogger, social media, website. And other people in their professional field or task
* Warning:
This app is not for someone who is involved in a fraudulent act or activities.
Anyone found who are involved in fraud is not welcome on this app platform
* Termination of account with immediate effect and without notice if found involved in fraudulence on this particular platform
Add Users.
We add users to this platform by whitelist as you send your email to creativeartssolutionfoundation@gmail.com
Guidelines
Creative Arts Solution Foun... is Ready
Congratulations, 'Creative Arts Solution Foun...' is created and ready to be configured. Install it on your device, continue customizing it in the editor & share it with your team!
Install Creative Arts Solution Foun...
Customize Creative Arts Solution Foun...
How to use the app
Step 1.
* Download Appsheet on your mobile through Google play store for (Android or iOS).
To install the app, open this link on your mobile device: bit.ly/2DEPWca
Use this install link on AppSheet to Run the app in your browser: bit.ly/2zT7Pzs
Sign in to AppSheet with any of this account below:
* Google (Gmail)
* Office365
* Dropbox
* Smartsheet
* Box
* Salesforce
Log out: You can log out when you are done.
Step 2
Click on the top button (left) to view the menu button: Document, Link website, Order Salesperson, Assistant, Feedback
Use the Bottom button for Share, Customer by the organization, organization chart, person, sync, as you click any of this button to view.
Step 3
Edit any of the already empty existing pages with sample photos by removing it and replace by uploading your photo and the organization as you edit and change the name to your name on our app platform and add your logo or photo. Etc.
* Email: Press the email icon to send an email by sharing with email or Gmail based on your mobile setting.
* Phone call: make a phone call with the app phone icon by clicking on it to call.
* Massager (Facebook massager) You can use the app to link Facebook massager. Message-Text and Video chat for free.
* Send SMS (short message service):
Send SMS with Hangout, messages using this app message icon
* Feedback: Use the feedback button to send us your opinion on app or others information
* App gallery: use the app gallery to view more of our existing app like Volunteer form- Creative Arts Solution Foundation.
Step 4
Share: click on the share icon button at the bottom of the customer as you place (upload) order photo of your work to be displayed.
Share the icon button on social media, platform like WhatsApp, Facebook, Twitter, Instagram, LinkedIn, YouTube Etc.
Please note the following as you may want to create a New App as you click on the top menu button (left) to locate the New App and create a new one for yourself of necessary as you want it.
Use free prototype/standard when to deploy your app.
Summary
Upgrade is available based on your app creator structure to determine what plan (Premium like Pro on a monthly fees charge or per annual payment fee to be paid per user or the app owner as they charge or debit your credit card based on the app setting when approved as it passes through test when you run it.
Visit our blog : creativeartssolutionfoundation.blogspot.com/2018/11/app-c...
For more information
Employment Application Process
Front row L to R: High School medalists—Silver-Codie Loftus, Boone Career Center & Technical Center (W.Va.); Gold-Braeden Santos, Greater New Bedford RVTHS (Mass.); and Bronze-Courtney Knihtila, Wilson Central High School (Tenn.); and, national technical committee member Yuette Weaver. Back row L to R: National technical committee member Diane Swenson; College/postsecondary medalists—Silver-Kimberly R NeSmith (Ga.); Gold-Dawn Fenton, Sheridan Technical College (Fla.); and Bronze-Connie Davis, Tennessee College of Applied Tech-Chattanooga, (Tenn.); and National Technical Committee Member Sherry Anderson.
Jillian Davis is my application for Bizarre.
The contest just sounds so good that i wanted to try.
Originally there are four polaroids but the other two are just too..
much failure - u can see them here when u wanna have eye cancer ;)
I introduced that sim before
but changed her hair color in that dark blue-ish
shade.
Stanford sits beside the junction on the M20 for Hythe and the junction with the bottom of the old Roman Road of Stone Street, and is the chosen location for the massive lorry park for any Brexit-related delays/jams. Only the DoT seemed to have forgotten to include an environmental impact assessment with the application, and was withdrawn.
Could still happen I guess, and the fine fellow in mustard coloured cords seemed to think it was still a possibility.
But for the time being, Stanford is quiet enough, with a fine looking pub, The Drum, and this mostly Victorian church, which I was rather taken with.
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What a delightful church! It is almost completely Victorian with the nave and chancel being rebuilt 30 years apart. The nave is severely plain, but the west windows may be part of the medieval church re-used. The font is a most unusual piece and is either Victorian or seventeenth century. It ahs certainly been recut over the years and has no Christian iconography. The chancel is well proportioned and entered via a well carved chancel arch. The east windows are shafted and have rere-arches. The stonework over the organ is typical late nineteenth century with castellations and niches, all probably designed by Carpenter. All in all this is a lovely church with a warm feeling and magnificent proportions. It deserves to be better known.
www.kentchurches.info/church.asp?p=Stanford
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THE next parish south-eastward from Horton is that of Stanford, which takes its name both from its soil and situation, slane in Saxon signifying a stone, and ford, a rivulet. The parish of Stanford itself lies in the hundred of Stowring, but that of Westenhanger, now united to it, is within the hundred of Street.
It is, the greatest part of it, a low unpleasant situation, lying at a small distance below the down hills. The greatest part of it is pasture ground, and very wet. The soil is very clity and poor near the hill, where the ground lies higher, but lower down it becomes richer, and has some good fertile meadows in it. There is but little wood, only two small coppices in the northern part of it; the rents are about 900l. per annum. The high road along the Stone-street way from Canterbury, and over Hampton hill, leads through this parish towards Newinn-green, whence it continues strait forward to Limne, the Portus Lemanis of the Romans, and to the right and left to Ashford and Hythe. Stanford-street is built on this road, in which there is a neat modern-built house, belonging to Mr. Jones, who lives in it; the church stands on a gentle rise eastward from it. The parish is watered by the stream which rises above Postling church, being the head of that branch of the river called the Old Stour, which running from thence hither, having been joined by several smaller streams from the north-west, crosses the high road westward below Stanford-street towards Ashford. The bridge under which it runs here, being broken down anno 7 Edward I. the jury found, that it ought to be repaired by Nicholas de Criol, and not by the adjacent hundreds. At a small distance westward from this bridge, and not far from the stream, stands the antient mansion of Westenhanger, having a gloomy appearance, in a low unpleasant situation, having an extent of flat country and pasture grounds in front of it, the above stream supplying the broad deep moat which surrounds it.
The ruins of this mansion, though very small, shew it to have been formerly a very large and magnificent pile of building. The antiquity of this mansion was, no doubt, very high, and if not originally built by one of the family of Criol, was afterwards much enlarged and strengthened by them. From one of the towers still retaining the name of Rosamond's tower, where the tradition is, that fair mistress of king Henry II. was kept for some time, it should seem to have been built before his reign, or perhaps even belonging to him. Which seems the more probable from there having been found among the ruins the left hand of a well carved statue, with the end of a sceptre grasped in it; a position peculiar to this prince, one of whose seals was so made in the life time of his father. (fn. 1) The scite of the house, moated round, had a drawbridge, a gatehouse and portal, the arch of which was large and strong, springing from six polygonal pillars, with a portcullis to it. The walls were very high, and of great thickness, the whole of them embattled, and fortified with nine great towers, alternately square and round, and a gallery reaching throughout the whole from one to the other. One of these, with the gallery adjoining to it on the north side, was called, as has been already mentioned, Fair Rosamond's; and it is suppoted she was kept here some time before her removal to Woodstock. The room called her prison, was a long upper one, of 160 feet in length, which was likewise called her gallery. Over the door of entrance into the house was carved in stone, the figure of St. George on horseback, and under it four shields of arms; one of which was the arms of England, and another a key and crown, supported by two angels. On the right hand was a slight of freestone steps, which led into a chapel, now a stable, curiously vaulted with stone, being erected by Sir Edward Poynings, in the reign of king Henry VIII. At each corner of the window of this chapel was curiously carved in stone, a canopy. There were likewise in it several pedestals for statues, and over the window stood a statue of St. Anthony, with a pig at his feet, and a bell hanging to one of its ears. At the west end were the statues of St. Christopher and king Herod. The great hall was fifty feet long, with a music gallery at one end of it, and at the other a range of cloisters which led to the chapel, and other apartments of the house. There were one hundred and twenty-six rooms in it, and, by report, three hundred and sixty-five windows. In the year 1701, more than three parts of it was pulled down, for the sake of the sale of the materials, which were then sold for 1000l. After this Mr. Champneis, the purchaser of it, converted the remainder into a small neat edifice for his residence; which house, within these few years, has been again pulled down, and a yet smaller modern one built on the scite of it. All that now remains therefore of this great mansion and its extensive surrounding buildings, are the walls and two towers on the north and east sides of it, which being undermined by length of time, are yearly falling in huge masses into the adjoining moat; and the remaining ruins being covered with ivy and trees, growing spontaneously on and through the sides of every part of them, exhibit an awful scene, and a melancholy remembrance of its antient grandeur; the under part of the great entrance yet remains, the arch over it having been taken down but lately; and there are numberless fragments of carved stone-work lying scattered about. The whole was built of quarry-stone, said to have been dug in the quarries of the adjoining manor of Otterpoole, in Limne, ornamented with sculptured stone brought from Caen. The park which belonged to this mansion, extended over the east and south parts of this parish, rather on rising ground, formerly comprehending the whole parochial district of Ostenhanger, at the southern boundary of which is New-Inn-green, so called from a new inn built there in king Henry the VIIIth's time, near which there is a small hamlet built on the road leading from Hythe to Ashford. Near the western boundary of the parish is a small green, built round with houses, called Gibbins brook, situated in the borough of Gimminge, its proper name, in a very wet and swampy country.
There was an annual fair instituted in 1758, to be holden in Stanford-street on June 7, for all sorts of cattle, but it was soon left off, and there has not been any held for near twenty years past.
THE MANOR OP STANFORD was antiently part of the possessions of the family of De Morinis, whose descendants the Derings continued afterwards to possess it. Sir Richard Dering, of Hayton, was owner of it anno 22 Richard II. and then quitted the possession of it to Sir Arnald St. Leger. (fn. 2) How it passed afterwards, I have not found; but in 1659 it was the property of Richard Busbridge, of Nottinghamshire, one of whose descendants sold it in 1699 to George Hamond, of Stanford, and he in 1733 alienated it to Michael Lade, of Canterbury, who parted with it again two years afterwards to Wile, of Sandwich, from which name it came to Mr. Odiarne Coates, of New Romney, whose heirs now possess it.
THE MANOR OF BEKEHURST, alias SHORNECOURT, lay somewhere in, or near this parish; for by the Book of Aid, levied anno 20 Edward III. it appears, that the heirs of Walter de Shorne paid aid for it, as the eighth part of a knight's see, which the said Walter before held in Bokehurst of John de Criell, as of his manor of Westenhanger. In king Henry VIII.'s reign, this manor was in the possession of Humphry Gay, gent. but in 1613 it was become the property of Sir Thomas Hardres, who that year levied a fine of it; but where it is situated, or who have possessed it since, I have not, with all my eldeavours, been able to discover.
HEYTON is another manor, lying at the north-west corner of this parish, next to Horton, being frequently mentioned in antient deeds by the name of Hayte. It was in very early times possessed by a family which took its surname from it, and bore for their cognizance in antient armorials, Gules, three piles, argent. Alanus de Heyton was owner of this manor in the reign of king Henry II. in which reign he held by knight's service of Gilbert de Magminot, but dying s.p. Elveva his sister, married to Deringus de Morinis, became his heir, and entitled her husband to it, and wrote himself, as appears by several dateless deeds, Dominus de Heyton. Their son Deringus Fitz Dering, was the first who deserted the name of Morinis, whose son Richard Fitz Dering, who likewise wrote himself Dominus de Heyton, died possessed of it at the latter end of the reign of king Henry III. and left it to his son Peter Dering, whose grandson Sir Richard Dering appears to have possessed it in the 22d year of king Richard II. and that year to have quitted the possession of it to Sir Arnald Seyntleger. After which it passed into the family of Scott, of Braborne, in which it continued till the reign of queen Elizabeth, when it was alienated by one of them to Mr. William Smith, of Stanford, yeoman, in whose descendants, resident at it, this manor continued down to Mr. William Smith, gent, of Heyton, who dying s.p. by will devised it to his widow Anne, daughter of Mr. John Drake, of London, and she having in 1769 remarried with the Rev. George Lynch, he in her right became possessed of it, and for some time resided here, till on the death of his brother Robert Lynch, M. D. he removed to Ripple, where he died in 1789, s.p. and by his will devised it to his two surviving sisters, who are the present possessors of it. (fn. 3) A court baron is held for this manor.
WESTENHANGER is an eminent manor here, which was once a parish of itself, though now united to Stanford: Its antient and more proper name, as appears by the register of the monastery of St. Angustine, was Le Hangre, yet I find it called likewise in records as high as the reign of Richard I. by the names both of Ostenhanger and Westenhanger, which certainly arose from its having been divided, and in the hands of separate owners, being possessed by the two eminent families of Criol and Auberville. Bertram de Criol, who was constable of Dover castle, lord warden of the five ports, and sheriff of Kent, for several years in the reign of king Henry III. who from his great possessions in this country, was usually stiled the great lord of Kent, is written in the pipe-rolls of the 27th year of that reign, of Ostenhanger, where it is said he rebuilt great part of the then antient mansion. He left two sons, Nicholas and John, the former of whom marrying with Joane, daughter and heir of Sir William de Aubervilse, inherited in her right the other part of this manor, called Westenhanger, as will be further mentioned hereafter. John, the younger son, seems to have inherited his father's share of this manor, called Ostenhanger, of which he died possessed in the 48th year of king Henry III. as did his son Bertram de Criol in the 23d year of Edward I. leaving two sons, John and Bertram, who both died s.p. and a daughter Joane, who upon the death of the latter became his heir, and carried Ostenhanger, among the rest of her inheritance, in marriage to Sir Richard de Rokesle, seneschal and governor of Poictu and Montreul in Picardy, a man of eminent character in that time, having been created a knight-banneret by king Edward I. at the siege of Carlaverock, in Scotland. He died without issue male, leaving his two daughters his coheirs, of whom Agnes, the eldest, married Thomas de Poynings; and Joane, the youngest, first Hugh de Pateshall, and secondly Sir William le Baud, and upon the division of their inheritance, Ostenhanger was wholly allotted to Thomas de Poynings, who died anno 13 Edward III. bearing for his arms, Barry of six, or, and vert, over all a bend, gules. He left three sons, Nicholas, Michael, and Lucas de Poynings, all three summoned at different times to parliament, among the barons of this realm. The descendants of the latter being summoned as barons Poynings de St. John, which barony became vested in the late duke of Bolton. Upon the division of their inheritance, this manor was allotted to the second son Michael, who died anno 43 king Edward III. and left two sons, Thomas and Richard. Thomas de Poynings, the eldest son, possessed it on his father's death, but he died anno 49 Edward III. s.p. having bequeathed his body to be buried in the midst of the choir of St. Radigund's, of his own patronage, before the high altar, appointing that a fair tomb should be placed over his grave, with the image of a knight made thereon. Upon his death, Richard de Poynings, his youngest brother, succeeded to it, and died possessed of it in the IIth year of king Richard II. as did his son Robert anno 25 Henry VI. having had two sons, Richard de Poynings, who died in his life-time, leaving a sole daughter and heir Alianore, who married Sir Henry Percy, afterwards earl of Northumberland, and brought him a large inheritance, together with the baronies of Poynings, Bryan, and Fitzpain, now enjoyed by the present duke of Northumberland; and a second son Robert, who succeeded his father in Ostenhanger, of which he died possessed anno 9 Edward IV. (fn. 4) who, as well as his several ancestors above-mentioned, were summoned among the barons to parliament, and his son Sir Edward Poynings, who having purchased the other part of this great manor, called Westenhanger, became possessed of the whole property of it, as will be further mentioned hereafter.
To return now to that part of this eminent manor, distinguished from its situation by the name of Westenhanger, which was in the reign of king Richard I. in the possession of the family of Auberville, one of whom, Sir William de Auberville, descended from William de Ogburville, mentioned in the survey of Domesday, being one of those who attended the Conqueror in his expedition hither, resided in that reign in the borough of Westenhanger, and was founder of the abbey of West Langdon, and a benefactor to the priory of Christ church, and as appears by his seal appendant to a deed in the Surrenden library, dated 29 Henry III. bore for his arms, Parted per dancette, two annulets in chief, and one in base. His grandson, of the same name, left an only daughter and heir Joane, who marrying with Nicholas de Criol, brought him this estate as part of her inheritance. His descendant Sir John de Criol, in the 19th year of Edward III. obtained a licence to found and endow a chantry in the chapel of St. John, in Westenhanger,; and before, in the 17th year of that reign, he had a grant to embattle and make loop-holes in his mansion-house of Westenhanger. His descendant Sir Nicholas de Criol, or Keriel, died possessed of it in the 3d year of king Richard II. and from him it devolved at length by succession to Sir Thomas Keriel, for so their name was then in general spelt, who was slain in the second battle of St. Albans, in the 38th year of Henry VI. in asserting the cause of the house of York. On his death without male issue, his two daughters became his coheirs, (fn. 5) viz. Elizabeth, married to John Bourchier, esq. and Alice, to John Fogge, esq. of Repton, afterwards knighted, whose second wife she was; and on the division of their inheritance, Westenhanger was allotted to the latter. He had by her one son, Sir Thomas Fogge, sergeant-porter of Calais in the reigns of king Henry VII. and VIII. who sold his interest in it to his elder brother, (by his father's first wise Alice Haut) Sir John Fogge, of Repton, and he, about the beginning of king Henry VIII.'s reign, alienated it to Sir Edward Poynings, the possessor of the other part of this manor, who thereupon became possessed of both Ostenhanger and Westenhanger, being the entire property of the whole manor. He was a man of much eminence of that time, and greatly in favour both with king Henry VII. and VIII. being governor of Dover castle, lord warden of the five ports, and knight of the garter. He resided at Westenhanger, where he began building magnificently, but he died before his stately mansion here was finished, anno 14 Henry VIII. having married Elizabeth, daughter of Sir John Scott, of Scotts-hall, by whom he had one only child John, who died in his life time; so that thus deceasing without legitimate issue, and even without any collateral kindred, who could make claim to his estates, this manor, among the rest of them, escheated to the crown. Although Sir Edward Poynings died without legitimate issue, yet he left by four different concubines three sons, Sir Thomas, who afterwards died s. p. Sir Adrian Poynings, who died without male issue; and Edward, slain at Bologne in the 38th year of Henry VIII. and likewise four daughters.
This manor thus becoming vested in the crown, was by the king's bounty soon afterwards conferred on his eldest natural son Sir Thomas Poynings abovementioned, who was a gentleman noted for the beauty and elegance of his person, and was of equal merit; and being of remarkable strength and courage, greatly signalized himself at the justs and tournaments of those times of which the king being himself exceedingly fond, it recommended him still more to the royal favour, and he was made K. B. and was summoned to parliament as baron Poynings, of Ostenhanger. But in the 32d year of the same reign, he, with dame Catherine his wife, exchanged this manor, park, and sundry premises belonging to it, with the king, for other estates in Dorsetshire and Wiltshire. (fn. 6) Soon after which, the king seems to have intended this manor as a mansion fit for his royal residence; for he not only expended much on the completing of the unfinished state of it, but two years afterwards laid into the park a large circuit of land, inclosing many mansions, houses, and buildings of the inhabitants within the pale of it; at which time this manor seems to have been indiscriminately called by both the names of Ostenhanger and Westenhanger. After which, the manor, together with the mansion, park, and other appurtenances belonging to it, continued in the hands of the crown till the reign of Edward VI. when that prince, in his first year, granted it with its appurtenances, to John Dudley, earl of Warwick, to hold in capite by knight's service; but in the 3d year of that reign, the earl joined with dame Joane his wife, in the reconveyance of it to the king, in exchange for premises in other counties. The next year after which the king granted it, among other premises, to Edward Fynes, lord Clinton, son of Thomas, lord Clinton, by Mary, one of the four daughters of Sir Edward Poynings before-mentioned, to hold in capite by knight's service, and in the 6th year of his reign, he made a new grant to him and Henry Herdson, his trustee of it, together with the advowson of the rectory, to hold by the like service; and they not long afterwards alienated the manor of Westenhanger with its appurtenances, to Richard Sackville, esq. who died possessed of it in the 8th year of queen Elizabeth; but it should seem that he had it only for his life, or perhaps might not be in possession of the mansion of Westenhanger itself; for that queen, in the progress which she made through this county, at the latter end of the summer in the year 1573, is said in the course of it to have stayed at her own house of Westenhanger, the keeper of which was then Thomas, lord Buckhurst, son of Richard Sackville, before-mentioned, And further, for that the queen, in her 27th year, granted the manor of Eastenhanger with its appurtenances, in see to Thomas Smith, esq. He was commonly called the Customer, from his farming the customs of the port of London, and he having greatly increased the beauty of this mansion, which had been impaired and defaced by fire, with magnificent additions, resided here; and when Lambarde wrote his Perambulation in 1570, there were here two parks, which continued till one of the family of Smith disparked them both. He died in 1591, and was succeeded by his eldest son Sir John Smythe, who was of Ostenhanger, where he kept his shrievalty in the 42d year of queen Elizabeth, and died in 1609. His son Sir Thomas Smythe, K. B. resided likewise at Westenhanger, (for by both these names this place was yet at times differently called) and was in 1628 created viscount Strangford, of the kingdom of Ireland. His son Philip, viscount Strangford, conveyed it to trustees, (fn. 7) and they, at the latter end of king Charles II.'s reign, alienated this manor, with its mansion, lands, and appurtenances, to Finch, who having in 1701 pulled down by far the greatest part of this stately mansion, then passed it away by sale to Justinian Champneis, esq. The family of Champneis are descended from Sir Amyan Champneis, who flourished in king Henry the IId's reign, whose descendants settled in Somersershire; one of whom, Robt. Champneis, of Chew, in that county, was father of Sir John Champneis, lord mayor of London anno 26 king Henry VIII. who was possessed of Hall-place, in Bexley, where he resided, and in which he was succeeded by his son, the youngest and only surviving son of seven, Justinian. One of his descendants, Walter Champneis, son of William, appears by the parish register of Boxley to have lived in that parish in queen Elizabeth's reign, anno 1582. After which there is continued mention in it of them down to the burial of Justinian Champneis, esq in 1712. Justinian Champneis, the purchaser of this estate, bore for his arms, Parted per pale, argent and sable, a lion rampant, gules, within a bordure, engrailed and counterchanged, of the field. He afterwards resided here, having built a smaller house on the same scite, out of the ruins remaining of it. He was one of the five Kentish gentlemen, who in 1701, delivered the noted petition from this county to the house of commons. He died possessed of this manor and estate, far advanced in years, in 1748, leaving three sons, Justinian, William, and Henry. On his death, by the settlement made on his marriage, one sixth part of this estate devolved to the two younger sons, and the rest of it on the eldest son Justinian Champneis, esq. who dying abroad, s. p. in 1754, gave by will his interest in it to his younger brother Henry; and the remaining sixth part came by compromise wholly to the then eldest surviving brother William Champneis, esq. who resided at Vintners, in Boxley. He left by his first wife two daughters his coheirs, Frances, now unmarried, and Harrior, who married John Burt, esq. of Rochester, by whom she had two sons, WilliamHenry and Thomas, and a daughter Harriot, as will be further mentioned hereafter. On his death in 1762, his sixth part of this estate came to his two daughters and coheirs before-mentioned, the eldest of whom, in her own right, and the two sons of John Burt, esq. deceased, in right of the youngest, is at this time entitled to it. The remaining part of this estate was by Henry Champneis, esq. of Vintners, in Boxley, who died unmarried in 1781, devised to his great nephew William-Henry Burt, the eldest son of John Burt, esq. by his wife Harriot before-mentioned, for whom he had in his life-time obtained a privy seal, to take the surname and bear the arms of Champneis. Which William-Henry Champneis, esq. is now entitled to the inheritance of it.
¶The parish of Ostenbanger stood, as to its ecclesiastical jurisdiction, in the deanry of Limne and diocese of Canterbury. The church, which was a rectory, was formerly in the patronage of the owners of the manor, and came to the crown on the death of Sir Edward Poynings, in the 14th year of king Henry VIII. whence it was granted, as appurtenant to the manor, to Sir Thomas Poynings, who in the 34th year of that reign, granted it to the crown in exchange; in which year the king having laid a large circuit of land into his park here, of which the rector had received the yearly tithes, and having likewise inclosed and imparked in it many houses, barns, and glebe-lands belonging to the rectory, and injoined the parishioners and inhabitants to resort to the parish to which they lay nearest, by which means the rector was destitute of a maintenance, granted to him for life, a yearly pension of six pounds, to be had of his treasurer of the Augmentation-office. Thus this parish became, as to its ecclesiastical juridiction, united to Stanford, to which church the owners of this estate, in whom the tithes of the whole of it are vested, pay a composition of eleven shillings as an acknowledgment for the privilege the inhabitants within it enjoy of the rites of the church there.
The rectory of Eastenhanger is valued in the king's books at 7l. 12s. 6d. and the yearly tenths at 15s. 3d. which are paid to the crown receiver, and not to the archbishop.
The church of Westenhanger has been entirely pulled down, and the materials removed, several years ago. It stood at a small distance westward of the house, and of the drawbridge at the entrance to it, between the latter and the great barn, which report says, was partly built out of the ruins of it. Several skeletons have from time to time been dug up within the scite of it and adjoining to it; and in some of the graves, several sculls in one grave; and some years ago a stone coffin was dug up. The font, which was in this church, was removed to, the church of Stanford, where it now remains.
I find the names of only two of the rectors of this parish, viz. William Lambard, in the 34th year of king Henry VIII. (fn. 8) and Thomas Eaton, A. M. presented by the crown in 1636. (fn. 9)
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