View allAll Photos Tagged Stemcell
“For every beauty there is an eye somewhere to see it.
For every truth there is an ear somewhere to hear it.
For every love there is a heart somewhere to receive it.”
~ Ivan Panin ~
Monday morning Frank was admitted to the hospital for his stem cell transplantation
Yesterday and today are Chemo days. Thursday will be a recovery day.
On Friday the stemcells will be transplanted.
Expectations are that the 2nd week in hospital will be the most difficult for him as he will most probably be suffering all kinds of side effects of the severe chemotherapy and his resistance level will be nil.
Hopefully he will recover soon ... and return home within 3 weeks.
This sweet little bird arrived in my garden this morning and must have thought he'd found paradise in the gruelling weather conditions! He stayed all day and of course spent most of that time eating! I've uploaded three images tonight all taken in my garden today.
This will be my last upload for a while so I'd like to take this opportunity to say a big thankyou to all of the people who have been kind enough to send their good wishes my way. I am being admitted to hospital tomorrow for chemotherapy and a stemcell transplant due to the Myeloma (cancer of the bone marrow) which I suffer from. I have drawn strength from all the love and kindness that has been shown to me by so many of you...there are a lot of wonderful people out there who really do care and it means a lot to me. I will be in hospital for several weeks but will try to drop in and comment when I can as I will be taking my computer tablet with me : )
An unidentified flying object (UFO) is any perceived aerial phenomenon that cannot be immediately identified or explained. On investigation, most UFOs are identified as known objects or atmospheric phenomena, while a small number remain unexplained, according Wikipedia.
Science fiction:
if the small number unexplained objects were space ships of aliens, it looks like they have a very high technology, far higher than us. Do their high technologies make them immortal? It depends on them how advance and smart they are.
It might be possible to create almost all the capabilities of a human being with advance science and technology, but the problem is the consciousness. How we get consciousness... Computers are already creating the thinking process. Computers can make a proper decision for us, but not for theirselves. Making decision for theirselves with being aware of their existence is consciousness. It looks like, whatever we do, we can not create consciousness. The difference between computers and us is we are alive. A living organism create consciousness. A proper hardware ( human ) is necessary to run a human-software. It has to have senses, feelings, thinking process ( creates commands ) and data saving mechanism. To create a human like creature, we have to make something alive first, so that it has to have fear from dying and defends itself. It has to feel pain too and has to try to ease the pain. The fear and pain are the dominating factors, noting else is really important than to be alive ( without pain ).
We will see what will happen in the future. An electronic living cell might be possible. If we are able to create a hardware similar to a human, some softwares could be available very easily, just hook up to the internet to get the necessary-information.The answers of the following questions might be available at the time when the hardware is ready: Who are the human? How do they function? How are the humans acting at a certain situation? How do they live? Are they aggressive? Do they kill each other? Do they just think to have a good time, don’t care anything else? How is the level of body produced drugs like serotonin and dopamine? Are they just like a sailing small boat on a very rough sea with no land on sight? Are they like a lost space ship in space? What are the flaws in their software and hardware? How do they walk? What is the meaning of their face impressions?
The creature might not be a biological one, important is the one which is alive. It doesn’t matter how it will be cerated. An electronic one could be the best solution. There is more potential at an electronic one than a biological one. Reactions and development could be very fast, software could be very easy to load ( not like biological one, at which it takes years, a lot schooling ) and it could be reloading possibilities if an information was missing. An electronic one could be immortal so long we keep the copy of the software safe for loading of the replacement of old, outdated hardware. The Hardware can be fixed anytime according the original blue print. Transportation will be very easy too, just send the software and blue print anywhere in space to create another one there, a copy.
Conclusions:
What is clear is we want to live longer, and if possible, we wan’t to live forever. Of course there are remedies. We are the product of chemical, physical, biological and phycological processes. There are no magic there, just science, technology and phycology. These processes can be changed under certain conditions to help us. The big problem is that we accept death. Traditionally, medicine has been focused on extending life, but it doesn’t help us to be immortal or to live a lot longer.
There are some institutions around the world they work on this issue, but it is not enough. Governments should very actively involve about it, creating ministry of longevity will be proper.
The most research is needed at cell level. The very important research areas are genetic engineering, stem-cell technology, cancer research, blood vessel clean up ( psychical and chemical ) and organ manufacturing and transplantation.
if the UFO owners were not smarter than us, their very advance computer technology loaded with the information about science, about technology and particularly about chemical, physical, biological and psychological processes of their body might have solved the problem, made them immortal. If they were smarter than us, they might have solved the problem without a very high technology.
Went to the President's Breakfast, an Ottawa Hospital fundraiser for their research initiative which are world class. Some breakthrough in MS, stem cell, and nerve transplants. We had four testimonies of patients that had innovative life saving operations, and they were gut wrenching. All of them said they were the luckiest people in the room. It's cliche, but it's makes you appreciate life even more after listening to their stories.
Yep folks - its Easter Sunday down under and I can feel peace and quiet has descended like a blanket all over Sydneytown. A great day to eat too much chocolate, get hyped up on sugar and then cuss and swear at photoshop tutorial videos that make sense for the first 3 minutes and then descend into complete confusion when they start talking oh so very fast about layers and masks.
Is there a Photoshop stemcell that I can clone off someone on here please ???? I know ....I will ask Jim or Amanda to donate one of their cells...check out their great work :
Jim : www.flickr.com/photos/shutterjack/17299355111/in/dateposted/
Amanda : www.flickr.com/photos/birdcloud1/25434075496/in/dateposted/
Thank you to all you wonderful guys on here who inspire me all the time with your amazing work and inspire me to push past the tutorial 3 minute barrier and persist with my learning . Happy Easter and remember that the bunny has brought free magical ef'eggs for everyone with NIk Software/Silver Efex now free for all to download :) .
Monument Valley Sunset ..
Looking back at the pictures from our vacation - spring 2014 - brings back bittersweet memories, because our holiday abruptly ended with 20 meter fall in the Waterholes Slot Canyon ... 5 days hospital and then straight back home.
We both recovered well, but my partners Multiple Myeloma desease returned in the meantime together with a far more frightening complication named Amyloidosis.
He's having chemo at least for 7 to 9 months, but even then prospects are not good, because his heart muscle is severly damaged and a new stemcell transplant can not be done ...
This explains my lack of presence on Flickr ... I hope someday my joy in photography will overtake the difficult times were going through at this moment ... For now it will be limited to a picture every once in a while
20120621NL Daisy van der S. is assistant professor at the Eindhoven University of Technology in the Netherlands. She works at the Department of Biomedical Engineering in the group of Soft Tissue Biomechanics & Engineering Eindhoven Netherlands #blackandwhite #233 #biomedical #engineering #softtissue #biomechanics #knownknowns&unknownknowns #art #realpeople #reallives #truestories #portraits #b&w #photography #instagram #street hughes-photography.eu www.flickr.com/photos/michael_hughes www.hughes.berlin
Science is a fine art through which you can explore the mystery of everything, so much things have to be discovered yet.
This is a picture taken by confocal microscopy, they are neurons derived from stem cell that I developed starting by blood cells. It was one of my biggest satisfaction! Through them you can explore several pathologies and disorders of the brain!
The biggest satisfaction by the way it’s when you try and try, and at the end you succeed in developing them! And after all the asleep nights and the mind burnouts, you know that your hardest work it’s just begun!!
Stem cells play important role in cell-based strategy for tissue regeneration. However, the conventional 'petri dish' based cell cultures do not truly replicate the complex 3D environments where cells naturally grow. In the Stupp laboratory, we are using photolithography to create textured surfaces that induce single stem cells to self-aggregate into microtissue. Compared to single stem cells, these aggregates are much more potent for regenerative medicine once implanted into the body. These specific cells will be used to grow new spinal bone.
In this image, microwells (light pink) of agarose gel were created using lithography, then each well was seeded with 250 stem cells (purple). These stem cells do not adhere to the microwell gel, but instead, they self-assembled together into microaggregates within 24 hours. The cells respond to this more natural environment by producing extracellular matrix (red) like collagen and proteoglycans. To our knowledge, this is the first ever SEM image of periosteal stem cells self-aggregating.
Courtesy of Dr. Mark McClendon , Northwestern University
Image Details
Instrument used: Quanta SEM
Magnification: 477X
Horizontal Field Width: 800um
Vacuum: 1 e-3Pa
Voltage: 5kV
Spot: 3
Working Distance: 6
Detector: SE
I have published a book, or rather, two editions of the same book, one in Italian and one in English, and I'm so excited about it. This is my first approach to publishing and I feel as if I'm throwing myself into the void.
The book is a diary based on the true story of Tancredi, a baby that suffered severe asphyxiation at birth. Writing about him has been one of the most spiritual adventure I have ever experienced. It has changed me more than anything else. It has just reduced the boundaries which, usually, separate one person from the other. It has given me a new vision of life and allowed me to share friendship with all the amazing people who have inspired and helped me through this path.
Now I'd like to share his story of courage and hope with you.
If you want to know more
www.the-diary-of-a-stubborn-child.com/
THE FORCE THAT MOVES US. THE DIARY OF A STUBBORN CHILD (English Edition)
Available on Amazon
The Force That Moves Us: The Diary of a Stubborn Child
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Ho pubblicato un libro, anzi due edizioni dello stesso libro, una in italiano e una in inglese, e sono emozionatissima. Questa è la mia prima incursione nell'editoria e mi sento come se mi stessi lanciando nel vuoto.
Il libro è un diario e racconta la vera storia di Tancredi un bimbo che ha subìto una grave asfissia alla nascita. Scrivere di lui è stata la più coinvolgente avventura che io abbia mai vissuto. Mi ha cambiata profondamente, riducendo i confini che solitamente separano gli uni dagli altri. Mi ha regalato una nuova visione e mi ha permesso di condividere sentimenti di amicizia con tutte quelle persone che, a diverso titolo, mi hanno ispirato e aiutato lungo questo percorso.
Adesso mi piacerebbe condividere la sua storia di coraggio e di speranza con voi.
Se voleste saperne di più
www.diario-di-un-bimbo-ostinato.com/
LA FORZA CHE CI MUOVE. DIARIO DI UN BIMBO OSTINATO
Disponibile su Amazon
La forza che ci muove: Diario di un bimbo ostinato
An innovative process that quickly turns human stem cells into millions of pain-sensing nerve cells could help researchers speed up the search for new pain therapies. Developed by NCATS scientists, this approach may be a template for other kinds of specialized human cells that are hard to make in large numbers. Read more: go.nih.gov/LyLP5NZ
Image shows pain-receptor neurons stained green and red to show cellular activity.
Credit: Tao Deng, NCATS Stem Cell Translation Laboratory, NIH
SARS-CoV-2 (magenta) infects alveolar and airway tissues (blue) of human mini-lungs derived in vitro from human pluripotent stem cells. Read more: www.rockefeller.edu/news/34104-lab-grown-mini-lungs-could...
Credit: Laboratory of Stem Cell Biology and Molecular Embryology at The Rockefeller University
NIH support from: NIAID
Soon came the day that my stem cells would be collected. The machine was plugged into my PICC line and I sat for a few hours while my cells were harvested.
Copyright © 2020 Vic Bonilla All Rights Reserved.
Do not reproduce this image without expressed permission from the photographer.
iPS cells reprogrammed from a woman's skin. Blue shows nuclei. Green indicate a protein found in reprogrammed cells but not in skin cells (NANOG). The red dots show the inactivated X chromosomes in each cell. These cells can be matured into cells of the body, and used for studying models of disease.
The image was taken in the laboratory of Kathrin Plath at the University of California, Los Angeles.
Learn more about CIRM-funded stem cell research: www.cirm.ca.gov.
Editor's note: great story we posted today about how a NASA light technology, originally developed for plant growth experiments in space, is being used to reduce the side effects of various medical treatments, including those for cancer, wounds, etc. You can read more about the technology here: www.nasa.gov/topics/nasalife/features/heals.html. I love success stories like this!
Special High Emissivity Aluminiferous Luminescent Substrate, or HEALS technology developed for NASA's commercial plant growth experiments in space is helping to treat cancer and save lives on Earth. NASA has partnered with Quantum Devices Inc. (QDI) of Barneveld Wis., to develop the WARP 75 light delivery system device for wound healing. A two-year clinical trial using the WARP 75 device on cancer patients undergoing bone marrow or stem cell transplants, concluded that there was a 96-percent chance that the improvement in pain relief of those in the high-risk patient group was the result of the HEALS treatment. The clinical trial was funded by NASA's Innovative Partnerships Program at the Marshall Space Flight Center in Huntsville, Ala. The NASA program works with industry and commercial partners to spinoff space technology and adapt it for new, innovative applications.
Image credit: NASA/MSFC/David Higginbotham
View more images:
www.nasa.gov/topics/nasalife/features/heals_photos.html
Watch a video of HEALS in action:
www.nasa.gov/multimedia/videogallery/index.html?media_id=...
A cross-section of an inner ear “organoid,” or mini inner ear, created by human stem cells. Sound-responding hair cells (red) of the inner ear are topped with hair cell bundles (yellow). Ear organoids could allow researchers to easily model and test therapies for hearing and balance disorders.
Credit: Karl R. Koehler, Ph.D., Indiana University School of Medicine
NIH support from: National Institute on Deafness and Other Communication Disorders (NIDCD)
This image shows mouse muscle cells viewed under a microscope. The cells have fused together to form myotubes that have many nuclei (stained blue). The cells are from mouse skeletal muscle stem cells treated with a harmless virus that caused them to glow green. The green color remained when the stem cells fused into myotubes. Some myotubes are stained red for a protein involved in muscle contraction (myosin heavy chain), a characteristic of mature muscle fibers. The researchers plan to use the same viral delivery system to genetically modify the cells and assess how impairing cell fusion alters myotube growth. This image was a 2017 winner in the BioArt competition of the Federation of American Societies for Experimental Biology (FASEB).
Credit: Kevin A. Murach, Ph.D., University of Kentucky
NIH support from: National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute on Aging
Editor's note: great story we posted today about how a NASA light technology, originally developed for plant growth experiments in space, is being used to reduce the side effects of various medical treatments, including those for cancer, wounds, etc. You can read more about the technology here: www.nasa.gov/topics/nasalife/features/heals.html. I love success stories like this!
Mitzi Macke, RN, a nurse in the Bone Marrow Transplant and Cellular Therapy Unit at the University of Alabama at Birmingham Hospital, demonstrates use of a WARP 75 device. The device uses High Emissivity Aluminiferous Luminescent Substrate, or HEALS, which is a type of LED technology that provides intense light energy. The innovation of the NASA HEALS technology provides the equivalent light energy of 12 suns from each of the 288 LED chips -- each the size of a grain of salt. The WARP 75 device is one of many devices using HEALS technology, developed in collaboration with NASA. The WARP 75 device was used for light therapy treatment on cancer patients during a two-year clinical trial funded by NASA's Innovative Partnerships Program at the Marshall Space Flight Center in Huntsville, Ala. The NASA program works with industry and medical partners to spinoff space technology and adapt it for new, innovative medical applications. The clinical trial found that 670 nanometers of light technology, used for plant growth experiments on the International Space Station, improved the painful side effects of chemotherapy and radiation in cancer patients undergoing bone marrow or stem cell transplants. The trial included 20 cancer patients from Children's Hospital of Wisconsin, and 60 cancer patients from the University of Alabama at Birmingham Hospital and the Children's Hospital of Alabama, also in Birmingham.
Image credit: NASA/MSFC/David Higginbotham
View more images:
www.nasa.gov/topics/nasalife/features/heals_photos.html
Watch a video of HEALS in action:
www.nasa.gov/multimedia/videogallery/index.html?media_id=...
Neurosphere composed of neural precursor cells as captured by a fluorescent microscope. The cells, allowed to attach to a substrate, have begun to send out long processes that will eventually become the axons of the mature neurons.
The image was taken in the lab of Martin Pera at the University of Southern California.
Learn more about CIRM-funded stem cell research: www.cirm.ca.gov
Unfortunately despite two trips this week to the Specialist Blood Donor Unit in Bristol I do not have enough stemcells in my blood to be collected for my planned transplant next month. I am now waiting for news from my consultant as to when I will be trying a new medication, which hopefully will work better than the last one at increasing the amount of stemcells so that we can try again. It's frustrating to have got this far in my treatment and then have this disappointment, but I know I must stay strong if I'm going to win this battle against myeloma so I'm hanging in there and hoping things will improve.
My apologies to my contacts for my lack of views and comments but I'm exhausted after my long road trips this week and will catch up again soon : )
The best way to study something is usually to look at it directly, but that can be difficult when it comes to studying nerve cells. That’s why a team of NIH researchers developed a way to take cells from an animal’s or person’s skin and turn them into stem cells, which can then be coaxed to develop into sensory neurons like this one. The process enables researchers to directly examine the behavior of neurons with the same #genes as the skin cells’ original donor.
Credit: NCCIH/NIH
Retinal ganglion cells are neurons that send information about light from the eye to the brain via a structure called the optic nerve. Here new neurons (green) and their supporting cells, called astrocytes (red), were created in a petri dish from stem cells. Making retinal ganglion cells and astrocytes from stem cells may one day help doctors rewire optic nerves damaged by glaucoma.
Credit: National Eye Institute, NIH
(Courtesy of Thomas V. Johnson, Naoki Nakaya, and Stanislav Tomarev of the NEI Laboratory of Retinal Cell and Molecular Biology, Molecular Mechanisms of Glaucoma Section)
Wound healing requires the action of stem cells. In mice that lack the Sept2/ARTS gene, stem cells involved in wound healing live longer and wounds heal faster and more thoroughly than in normal mice. This confocal microscopy image from a mouse lacking the Sept2/ARTS gene shows a tail wound in the process of healing. Cell nuclei are in blue. Red and orange mark hair follicle stem cells (hair follicle stem cells activate to cause hair regrowth, which indicates healing).
Credit: Yaron Fuchs and Samara Brown, National Institutes of Health
Red: neuronal marker TUJ1 (beta III tubulin).
Green: cortical marker CUX-1.
Blue: nuclear marker DAPI.
Credit: National Center for Advancing Translational Sciences, NIH
I am beginning to long for the new life and colours that Spring will bring... but that is not the only reason I am looking forward to Spring.
I have some good news for my Flickr friends. As you may know for the past few months I have been undergoing treatment for the cancer Myeloma. Well the treatment has been working well and I am now at the point where I shall be undergoing a stemcell transplant later on this month. My paraprotein level has dropped to 2 and it is now safe to start harvesting my stemcells. They will be frozen and kept whilst I undergo radical chemotherapy to kill off any remaining cancer cells before the healthy stemcells are then transplanted back into me. It is not a cure, as Myeloms is incurable and will return at some stage, but hopefully if all goes well it will give me a few more years before it returns.
It's been a struggle getting this far but I made it! And although undergoing the stemcell transplant is going to be a pretty rough ride I'll give it my best shot and hopefully by the time Spring arrives I will be feeling so much better. The damage the myeloma has caused to my spine is something which cannot be healed and at this point my spine is broken in my lower back so pursuing my love of nature photography is not possible right now. But by Spring, and as the weather warms up, and with David by my side encouraging me, I am hoping that I will find my pain easing and that my determination will get me back out there with my camera before too long: )
CRISPR/Cas9 engineering was used in mouse embryonic stem cells to insert a GFP tag in frame with the motor-neuron-specific transcription factor HB9. These cells were differentiated into motor neurons. The resulting motor neuron nuclei are labeled with the GFP reporter (green) and counterstained with antibodies against the neuronal marker Tuj1 (red).
Credit: T. Macfarlan, National Institute of Child Health and Human Development, NIH
Osteochondroretricular stem cells (red) are a newly identified type of bone stem cell that appears to be vital to skeletal development. Research on these stem cells may lead to treatments for osteoarthritis, osteoporosis and fractures.
Credit: Timothy C. Wang, M.D., Columbia University
This image is not owned by the NIH. It is shared with the public under license. If you have a question about using or reproducing this image, please contact the creator listed in the credits. All rights to the work remain with the original creator.
NIH support from: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Dr. Anthony Atala shows a kidney created layer by layer by the printer in the background. A modified desktop ink jet printer sprays cells instead of inks. The cells are cultured from the patient and the structural template for the kidney comes from MRI scans (so it will be the right size and shape).
The TED Video just went online.
Using similar technology, Atala constructed a bladder for a young boy, Jake, 10 years ago. At the end of the talk (photo below), Jake rejoined the good doctor on stage to thank him.
A fluorescent microscopic image of hundreds of human embryonic stem cells in various stages of differentiation into neurons. Some cells have become neurons (red), while others are still precursors of nerve cells (green). The yellow is an imaging artifact that results when cells in both stages are on top of each other.
The image was taken in the lab of Guoping Fan at the University of California, Los Angeles.
Learn more about CIRM-funded stem cell research: www.cirm.ca.gov
Runner-up
Dr Gabor Foldes, Prof Sian Harding, BHF Chair Prof Michael Schneider & Dr Nadire Ali
Imperial College, London (BHF Centre of Research Excellence)
This image shows heart muscle cells that have been grown from stem cells in the laboratory. The components of these cells have been stained with fluorescent pigments: the nuclei are red and the protein filaments that make the muscle contract are green and blue.
It is hoped that tissue grown from stem cells could be developed for future transplantation therapy in people with heart rhythm disturbances and heart failure caused by heart attacks.
“Our BHF-funded research is aiming to understand the fundamental biology of these exciting cells. Once we know more about how they grow and turn into beating heart cells, we hope to be able to harness them to repair damaged hearts.”
Dr Gabor Foldes
A cluster of nascent retinae generated from 3D embryonic stem cell cultures. The retinae contain photoreceptor precursors that express normal photoreceptor proteins, including the visual pigment, Rhodopsin (green) and the phototransduction enzyme, Recoverin (red). The precursors from such retinae can be isolated and transplanted into adult mice.
Image by Anai Gonzalez-Cordero.
Read the press release at: bit.ly/1dPdfrp
"Why Files” 2015 Cool Science Image Contest winning photo by Scott Vermilyea, Neuroscience Training Program, School of Medicine and Public Health and neurobiology undergraduate Scott Guthrie, with SCRMC members Ted Golos and Marina Emborg, professors in the School of Medicine and Public Health and Wisconsin National Primate Research Center. Golos is also a faculty member in the School of Veterinary Medicine.
Funding from the NIH Office of Research and Structured Programs (ORIP) to the Wisconsin National Primate Research Center to explore stem cell related solutions for Parkinson’s disease.
This image was chosen as a winner of the 2016 NIH funded research image call.
This image is not owned by the NIH. It is shared with the public under license. If you have a question about using or reproducing this image, please contact the creator listed in the credits. All rights to the work remain with the original creator.
Credit: Scott Vermilyea, Neuroscience Training Program, School of Medicine and Public Health and neurobiology undergraduate Scott Guthrie, with SCRMC members Ted Golos and Marina Emborg, professors in the School of Medicine and Public Health and Wisconsin National Primate Research Center.
NIH funding from: Office of Research Infrastructure Programs
Electron microscope image provides a close-up view of a 3-D woven scaffold on which stem cells were grown.
More information: www.nih.gov/news-events/nih-research-matters/stem-cells-g...
This image is not owned by the NIH. It is shared with the public under license. If you have a question about using or reproducing this image, please contact the creator listed in the credits. All rights to the work remain with the original creator.
Credit: Guilak lab, Washington University
NIH funding from: National Institute of Arthritis and Musculoskeletal and Skin Diseases
A nascent retina, generated from a 3D embryonic stem cell culture, containing photoreceptor precursors expressing normal photoreceptor proteins, including the visual pigment, Rhodopsin (green) and the transcription factor, Crx (red). The precursors from such retinae can be isolated and transplanted into adult mice.
Image by Anai Gonzalez-Cordero.
Read the press release at: bit.ly/1dPdfrp
iPS cells reprogrammed from a woman's skin. Blue shows nuclei. Green and red indicate proteins found in reprogrammed cells but not in skin cells (TRA1-62 and NANOG). These cells can be matured into cells of the body, and used for studying models of disease.
The image was taken in the laboratory of Kathrin Plath at the University of California, Los Angeles.
Learn more about CIRM-funded stem cell research: www.cirm.ca.gov.
Adult-like cardiac tissue engineered from human pluripotent stem cells contains transverse tubules, the hallmark of maturity, seen in immunofluorescent images. Researchers are now able to use induced pluripotent stem cells (iPSC) to form a model of human adult-like cardiac muscle by introducing electric and mechanical stimulation at an early stage. Since this muscle is similar to the adult heart, it could serve as a better model for testing the effects of drugs and toxic substances than current tissue-engineered heart models.
More information: www.nih.gov/news-events/news-releases/early-stimulation-i...
Credit: Columbia University
NIH support from: National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Researchers have determined that the protein complex TFIID controls stem cell genes that repair skeletal muscle. This image shows human differentiated skeletal muscle fibers (myotubes, in green) expressing the protein MyoD (stained in red), which cooperates with TFIID in causing muscle stem cells to become muscle tissue. Cell nuclei are stained in blue. This discovery may help develop strategies that activate stem cells to repair muscle degenerated by aging or diseases like muscular dystrophy and cancer.
This image is not owned by the NIH. It is shared with the public under license. If you have a question about using or reproducing this image, please contact the creator listed in the credits. All rights to the work remain with the original creator.
Credit: Alessandra Dall'Agnese, Sanford-Burnham Prebys Medical Discovery Institute
NIH funding from: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Fluorescent microscope image of human embryonic stem cells. Nuclei stained green indicate stem cells. Those stained blue are the surrounding supportive feeder cells.
This photo was taken in the lab of Michael Longaker at the Stanford University School of Medicine.
Learn more about CIRM-funded stem cell research: www.cirm.ca.gov
An NIH surgical team successfully implanted a patch of tissue made from patient cells with the goal of treating advanced “dry” age-related macular degeneration (AMD), also known as geographic atrophy. Dry AMD is a leading cause of vision loss among older Americans and currently has no treatment.
Read more: www.nih.gov/news-events/news-releases/first-us-patient-re...
Image: Left shows an image of the full-RPE-patch (2 x 4 mm). Each dot is an RPE cell with the borders stained green. Each patch contains approximately 75,000 RPE cells. Right image shows patch RPE cells at higher magnification.
Credit: Kapil Bharti, Ph.D., NEI, NIH