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this team is making drug capsules in small volume for a clinical trial, for
an unnamed client pharma company. They work for Pharmatek in San Diego.
We are providing great Pilates Clinical( www.chelsealongbeachphysiotherapy.com.au/services/pilates/ )for your fitness. Our Clinical Pilates is great for injury prevention, especially in high-impact sports. Pilates is an innovative and safe system of mind-body exercise using a floor mat or a variety of equipment. Our Clinical Pilates can help you to build strength, stability.
Pilates Clinical( www.chelsealongbeachphysiotherapy.com.au/services/pilates/ )is a restoration type of treatment concentrating on reestablishing typical development, stance and muscle adjust inside the body. This is focused on explicit territories to advance mending, to avoid re-damage and improve generally versatility and capacity. Our Pilates Clinical instructors are experts in recovery and pain management.
Clinical Pilates( www.chelsealongbeachphysiotherapy.com.au/services/pilates/ )is taught to you by our physiotherapists and will help you to build stability in the muscles that are essential to spinal stability. Our Clinical Pilates can help you to build the strength, stability, and range of movement required to perform your daily and sporting activities with less pain and dysfunction.
Earn a PsyD in Clinical Psychology allows the practitioner to diagnose, treat, prevent, and assess mental illness.
On my way back from Reading I met up with Ray to go have a quick look around the recently closed St.johns Hospital in Chelmsford. I wasnt so sure what to expect from such a new location, having been occupied only months before but I found it to be one of the best and eeriest locations ive done since my first ever explore. clean, clinical and full of atmosphere this site eccoed the film 28days later with remanences of the individuals and lives lived and lost in the building. Shot with my Nikon D50 and Nikkor 50mm lense
Applying steril gloves as part of the Aseptic Technique.
See this inside Clinical Skills Made Incredibly Easy UK Editions at www.madeincrediblyeasy.co.uk/details.php?isbn=97819018310...!
Clinical specimen testing for novel coronavirus (COVID-19) at New York State Department of Health's Wadsworth Laboratory.
Clinical nurse Ermias Amare marks the home of Sophia Abdi with a half-tick, indicating that not all the children in the family have received their polio shots during this round of Polio NIDs. Ermias and his partner will return the next day to vaccinate Sophia's five year old daughter who is out tending the familis goats on this day. ©UNICEF Ethiopia/2015/Getachew
Grad students run a mock code on "sim man" clinical simulation in the Learning Resource Center in the Frances Payne Bolton School of Nursing at Case Western Reserve University in Cleveland, Ohio on Friday, April 24, 2009. Photo by David Ahntholz
Short hair/glasses: PhD student Mary DeHaan
Teaching assistants (white coats): Dana Deliberato (dark hair) and Irina Shuster (blonde hair)
Students: Laura Ross, Katie Pozzi (blonde, ponytail); Nora Plisga, and Kate Pollick (brown hair/IV)
Um texto, em português, da Wikipédia:
Hibiscus
Hibiscus L. é um gênero botânico, com cerca de 300 espécies, inserido na família das Malvaceae, com flores e folhas exuberantes. Devido à nova taxonomia pela filogenética (Angiosperm Phylogeny Group), muitas espécies que pertenciam a esse gênero estão migrando para outros gêneros. Por exemplo: Hibiscus esculentus L., a planta do quiabo, agora é Abelmoschus esculentus (L.) Moench. O cultivo dos exemplares do gênero, tanto ornamental como econômico, está disseminado nas regiões subtropicais e tropicais, cuidando para não sofrerem com geadas e temperaturas baixas constantes.
Etimologia:
Hibiscus significa Ísis (deusa egípcia), em grego.
Sinonímia:
Bombycidendron Zoll. & Moritzi
Bombycodendron Hassk.
Brockmania W. Fitzg.
Fioria Mattei
Espécies:
Hibiscus acetosella
Hibiscus x archeri (híbrido)
Hibiscus arnottianus
Hibiscus bifurcatus
Hibiscus brackenridgei
Hibiscus calyphyllus
Hibiscus cameronii
Hibiscus cannabinus
Hibiscus chitra
Hibiscus cisplatinus
Hibiscus clayi
Hibiscus coccineus
Hibiscus denisonii
Hibiscus diversifolius
Hibiscus elatus
Hibiscus furcellatus
Hibiscus fuscus
Hibiscus grandiflorus
Hibiscus hastatus
Hibiscus heterophyllus
Hibiscus indicus
Hibiscus kokio
Hibiscus lasiocarpos
Hibiscus lavaterioides
Hibiscus lobatus
Hibiscus ludwigii
Hibiscus macrophyllus
Hibiscus mastersianus
Hibiscus militaris
Hibiscus moscheutos
Hibiscus mutabilis (malva-rosa)
Hibiscus paramutabilis
Hibiscus pedunculatus
Hibiscus pernambucensis (guanxuma-do-mangue)
Hibiscus platanifolius
Hibiscus radiatus
Hibiscus rosa-sinensis (hibisco)
Hibiscus sabdariffa (vinagreira)
Hibiscus schizopetalus (hibisco-crespo)
Hibiscus scottii
Hibiscus sinosyriacus
Hibiscus splendens
Hibiscus syriacus (hibisco-da-síria)
Hibiscus tiliaceus (algodoeiro-da-praia)
Hibiscus trionum (flor-de-todas-as-horas)
Hibiscus waimeae
Hibiscus dioscorides
Hibiscus diriffan
Hibiscus escobariae
Hibiscus noli-tangere
Hibiscus quattenensis
Hibiscus socotranus
Hibiscus stenanthus
Portugal:
Em Portugal este género está representado por 2 espécies, presentes em Portugal Continental, a primeira nativa, a segunda introduzida:1
Hibiscus palustris L.
Hibiscus trionum L.
Classificação do gênero:
Sistema Classificação Referência
Linné Classe Monadelphia, ordem Polyandria Species plantarum (1753)
Papuodendron C. T. White
Pariti Adans.
Talipariti Fryxell
Wilhelminia Hochr.
A text, in english, from Wikipedia, the free encyclopedia:
Hibiscus
For other uses, see Hibiscus (disambiguation).
Hibiscus
Hibiscus flower TZ.jpg
Hibiscus rosa-sinensis
Scientific classification
Kingdom: Plantae
Division: Angiosperms
Class: Eudicots
Order: Malvales
Family: Malvaceae
Subfamily: Malvoideae
Tribe: Hibisceae
Genus: Hibiscus
L.
Species
232 species
Synonyms
Bombycidendron Zoll. & Moritzi
Bombycodendron Hassk.
Brockmania W.Fitzg.
Pariti Adans.
Wilhelminia Hochr.
Hibiscus (/hɨˈbɪskəs/ or /haɪˈbɪskəs/) is a genus of flowering plants in the mallow family, Malvaceae. It is quite large, containing several hundred species that are native to warm-temperate, subtropical and tropical regions throughout the world. Member species are often noted for their showy flowers and are commonly known simply as hibiscus, or less widely known as rose mallow. The genus includes both annual and perennial herbaceous plants, as well as woody shrubs and small trees. The generic name is derived from the Greek word ἱβίσκος (hibískos), which was the name Pedanius Dioscorides (ca. 40–90) gave to Althaea officinalis.
Description:
The leaves are alternate, ovate to lanceolate, often with a toothed or lobed margin. The flowers are large, conspicuous, trumpet-shaped, with five or more petals, color from white to pink, red, orange, purple or yellow, and from 4–18 cm broad. Flower color in certain species, such as H. mutabilis and H. tiliaceus, changes with age.[5] The fruit is a dry five-lobed capsule, containing several seeds in each lobe, which are released when the capsule dehisces (splits open) at maturity. It is of red and white colours. It is an example of complete flowers.
Uses:
Symbolism and culture
Hibiscus species represent nations: Hibiscus syriacus is the national flower of South Korea, and Hibiscus rosa-sinensis is the national flower of Malaysia. The hibiscus is the national flower of Haiti. The red hibiscus is the flower of the Hindu goddess Kali, and appears frequently in depictions of her in the art of Bengal, India, often with the goddess and the flower merging in form. The hibiscus is used as an offering to goddess Kali and Lord Ganesha in Hindu worship.
In the Philippines, the gumamela (local name for hibiscus) is used by children as part of a bubble-making pastime. The flowers and leaves are crushed until the sticky juices come out. Hollow papaya stalks are then dipped into this and used as straws for blowing bubbles.
The hibiscus flower is traditionally worn by Tahitian and Hawaiian girls. If the flower is worn behind the left ear, the woman is married or in a relationship. If the flower is worn on the right, she is single or openly available for a relationship. The hibiscus is Hawaii's state flower.
Nigerian author Chimamanda Ngozi Adichie named her first novel Purple Hibiscus after the delicate flower.
The bark of the hibiscus contains strong bast fibres that can be obtained by letting the stripped bark set in the sea to let the organic material rot away.
Landscaping
Many species are grown for their showy flowers or used as landscape shrubs, and are used to attract butterflies, bees, and hummingbirds.
Paper
One species of Hibiscus, known as kenaf (Hibiscus cannabinus), is extensively used in paper-making.
Beverage
Main article: Hibiscus tea
The tea made of hibiscus flowers is known by many names in many countries around the world and is served both hot and cold. The beverage is well known for its color, tanginess and flavor.
It is known as bissap in West Africa, agua de jamaica in Mexico and Honduras (the flower being flor de jamaica) and gudhal (गुड़हल) in India. Some refer to it as roselle, a common name for the hibiscus flower. In Jamaica, Trinidad and many other islands in the Caribbean, the drink is known as sorrel (Hibiscus sabdariffa; not to be confused with Rumex acetosa, a species sharing the common name sorrel). In Ghana, the drink is known as soobolo in one of the local languages.
Roselle is typically boiled in an enamel-coated large stock pot as most West Indians believe the metal from aluminum, steel or copper pots will destroy the natural minerals and vitamins.[citation needed]
In Cambodia, a cold beverage can be prepared by first steeping the petals in hot water until the colors are leached from the petals, then adding lime juice (which turns the beverage from dark brown/red to a bright red), sweeteners (sugar/honey) and finally cold water/ice cubes.
In Egypt,[citation needed] Sudan and the Arab world, hibiscus tea is known as karkadé (كركديه), and is served as both a hot and a cold drink.
Food
Dried hibiscus is edible, and it is often a delicacy in Mexico. It can also be candied and used as a garnish.
The roselle (Hibiscus sabdariffa) is used as a vegetable. The species Hibiscus suratensis Linn synonymous to Hibiscus aculeatus G. Don is noted in Visayas Philippines being a souring ingredient for almost all local vegetables and menus. Known as Labog in the Visayan area, (or Labuag/Sapinit in Tagalog), the species is a very good ingredient in cooking native chicken soup. Certain species of hibiscus are also beginning to be used more widely as a natural source of food coloring (E163),[citation needed] and replacement of Red #3 / E127.
Hibiscus species are used as food plants by the larvae of some Lepidopteran species, including Chionodes hibiscella, Hypercompe hambletoni, the nutmeg moth, and the turnip moth.
Health benefits
The tea is popular as a natural diuretic; it contains vitamin C and minerals, and is used traditionally as a mild medicine.
A 2008 USDA study shows consuming hibiscus tea lowers blood pressure in a group of prehypertensive and mildly hypertensive adults. Three cups of tea daily resulted in an average drop of 8.1 mmHg in their systolic blood pressure, compared to a 1.3 mmHg drop in the volunteers who drank the placebo beverage. Study participants with higher blood pressure readings (129 or above) had a greater response to hibiscus tea: their systolic blood pressure went down by 13.2 mmHg. These data support the idea that drinking hibiscus tea in an amount readily incorporated into the diet may play a role in controlling blood pressure, although more research is required.
Studies have demonstrated the anti-hypertensive effects of H. sabdariffa in both humans and animals. It has been proposed that the antihypertensive effects of H. sabdariffa is due to its angiotensin-converting enzyme inhibiting activity. In a randomized, controlled clinical trial involving 39 patients with mild to moderate hypertension, Captopril was compared to an extract of H. sabdariffa for antihypertensive effects. Subjects taking an extract of H.sabdariffa, consumed daily before breakfast for four weeks, found reduction in blood pressure similar to Captopril. Another randomized, placebo clinical trial involving 54 study participants with moderate hypertension demonstrated a reduction in both systolic and diastolic blood pressure. However upon discontinuation of treatment, both systolic and diastolic blood pressures were subsequently elevated.
Hibiscus rosa-sinensis has a number of medical uses in Chinese herbology. Lokapure s.g.et al. their research indicates some potential in cosmetic skin care; for example, an extract from the flowers of Hibiscus rosa- sinensis has been shown to function as an anti-solar agent by absorbing ultraviolet radiation.
In the Indian traditional system of medicine, Ayurveda, hibiscus, especially white hibiscus and red hibiscus (Hibiscus rosa-sinensis), is considered to have medicinal properties. The roots are used to make various concoctions believed to cure ailments such as cough, hair loss or hair greying. As a hair treatment, the flowers are boiled in oil along with other spices to make a medicated hair oil. The leaves and flowers are ground into a fine paste with a little water, and the resulting lathery paste is used as a shampoo plus conditioner.
Hibiscus tea also contains bioflavonoids, which are believed to help prevent an increase in LDL cholesterol, which can increase the buildup of plaque in the arteries.
A previous animal study demonstrated the effects of H.sabdariffa extract on atherosclerosis in rabbits. Notably, a reduction in triglyceride, cholesterol, and low-density lipoprotein was observed in rabbits consuming a high cholesterol diet (HCD) in addition to H.sabdariffa extract compared to rabbits only fed HCD, suggesting a beneficial effect.[16] Furthermore, the H. sabdariffa seed is abundant in phytosterol and tocopherol, plant forms of cholesterol that have antioxidant and LDL cholesterol lowering effects.
Precautions and Contraindications:
Pregnancy and Lactation
While the mechanism is not well understood, previous animal studies have demonstrated both an inhibitory effect of H. sabdariffa on muscle tone and the anti-fertility effects of Hibiscus rosa-sinensis, respectively. The extract of H. sabdariffa has been shown to stimulate contraction of the rat bladder and uterus; the H.rosa-sinensis extract has exhibited contraceptive effects in the form of estrogen activity in rats. These findings have not been observed in humans. The Hibiscus rosa-sinensis is also thought to have emmenagogue effects which can stimulate menstruation and, in some women, cause an abortion. Due to the documented adverse effects in animal studies and the reported pharmacological properties, the H. sabdariffa and H.rosa-sinensis are not recommended for use during pregnancy. Additionally, they are not recommended while breastfeeding due to the lack of reliable information on its safety and use.
Contraindications
No contraindications have been identified.
Adverse Effects
Drug Interactions
It is postulated that H. sabdariffa interacts with diclofenac, chloroquine and acetaminophen by altering the pharmacokinetics. In healthy human volunteers, the H. sabdariffa extract was found to reduce the excretion of diclofenac upon co-administration. Additionally, co-administration of Karkade (H. sabdariffa), a common Sudanese beverage, was found to reduce chloroquine bioavailability. However, no statistically significant changes were observed in the pharmacokinetics of acetaminophen when administered with the Zobo (H.sabdariffa) drink. Further studies are needed to demonstrate clinical significance.
Species:
In temperate zones, probably the most commonly grown ornamental species is Hibiscus syriacus, the common garden hibiscus, also known in some areas as the "Rose of Althea" or "Rose of Sharon" (but not to be confused with the unrelated Hypericum calycinum, also called "Rose of Sharon"). In tropical and subtropical areas, the Chinese hibiscus (H. rosa-sinensis), with its many showy hybrids, is the most popular hibiscus.
Several hundred species are known, including:
Hibiscis acapulcensis
Hibiscus acetosella Welw. ex Hiern.—False Roselle
Hibiscus acicularis
Hibiscus aculeatus—Comfortroot
Hibiscus altissimus
Hibiscus andongensis
Hibiscus angolensis
Hibiscus aponeurus[26]
Hibiscus archeri—Archer's Hibiscus
Hibiscus aridicola
Hibiscus arnottianus A.Gray—Kokiʻo ʻula (Hawaii)
Hibiscus asper—Bush Roselle
Hibiscus austroyunnanensis
Hibiscus barbosae
Hibiscus benguellensis
Hibiscus berberidifolius
Hibiscus bernieri
Hibiscus bifurcatus—Fork-bracted Rosemallow
Hibiscus biseptus—Arizona Rosemallow
Hibiscus bojerianus
Hibiscus boryanus—Foulsapate Marron
Hibiscus brackenridgei A.Gray—Hawaiian hibiscus Maʻo hau hele
Hibiscus burtt-davyi
Hibiscus caerulescens
Hibiscus caesius—Dark-eyed Hibiscus (South Africa)
Hibiscus calyphyllus—Lemonyellow Rosemallow (Tropical Africa)
Hibiscus cameronii—Cameron's Hibiscus, Pink Hibiscus
Hibiscus cannabinus L.—Kenaf
Hibiscus castroi
Hibiscus cisplatinus—Rosa Del Rio
Hibiscus citrinus-
Hibiscus clayi O.Deg. & I.Deg.—Hawaiian red hibiscus (Hawaii)
Hibiscus clypeatus—Congo Mahoe
Hibiscus coccineus (Medik.) Walter—Scarlet Rosemallow
Hibiscus colimensis
Hibiscus columnaris—Mahot Rempart
Hibiscus comoensis
Hibiscus congestiflorus
Hibiscus costatus
Hibiscus coulteri—Desert Rosemallow
Hibiscus cuanzensis
Hibiscus dasycalyx—Neches River Rosemallow
Hibiscus denudatus Benth.—Pale Face (Southwestern United States, Northwestern Mexico)
Hibiscus dimidiatus
Hibiscus dioscorides A.G.Mill. (es/pt) (Yemen)
Hibiscus diplocrater
Hibiscus diriffan A.G.Mill. (Yemen)
Hibiscus diversifolius—Swamp Hibiscus
Hibiscus dongolensis
Hibiscus donianus
Hibiscus elatus—Mahoe
Hibiscus elegans
Hibiscus engleri—Wild Hibiscus
Hibiscus escobariae
Hibiscus excellii
Hibiscus ferrugineus
Hibiscus ficalhoanus
Hibiscus flavoroseus
Hibiscus fragilis DC.—Mandrinette (Mascarene Islands)
Hibiscus fragrans
Hibiscus fritzscheae
Hibiscus furcellatus Desr.—Lindenleaf rosemallow (Caribbean, Florida, Central America, South America, Hawaii)
Hibiscus fugosioides
Hibiscus furcellatus—Salad Hibiscus
Hibiscus fuscus
Hibiscus genevii Bojer (Mauritius)
Hibiscus gilletii
Hibiscus gossweileri
Hibiscus grandidieri
Hibiscus grandiflorus Michx.—Swamp rosemallow (Southeastern United States)
Hibiscus grandistipulatus
Hibiscus grewiifolius
Hibiscus hamabo
Hibiscus hastatus
Hibiscus heterophyllus—Native rosella
Hibiscus hirtus—Lesser Mallow
Hibiscus hispidissimus
Hibiscus huellensis
Hibiscus hybridus
Hibiscus indicus
Hibiscus insularis Endl.—Phillip Island hibiscus (Phillip Island)
Hibiscus integrifolius
Hibiscus jaliscensis
Hibiscus kochii
Hibiscus kokio—Red Rosemallow
Hibiscus labordei
Hibiscus laevis All. (=H. militaris)—Halberd-leaved rosemallow (central and eastern North America)
Hibiscus lasiocarpos—Woolly Rosemallow
Hibiscus lasiococcus
Hibiscus lavaterioides
Hibiscus laxiflorus
Hibiscus leptocladus ([Northwest Australia])
Hibiscus leviseminus
Hibiscus lilacinus—Lilac Hibiscus
Hibiscus liliiflorus—Rodrigues Tree Hibiscus
Hibiscus longifolius
Hibiscus longisepalus
Hibiscus ludwigii
Hibiscus lunariifolius
Hibiscus macrogonus
Hibiscus macrophyllus—Largeleaf Rosemallow
Hibiscus macropodus
Hibiscus makinoi—Okinawan Hibiscus
Hibiscus malacophyllus Balf.f. (Yemen)
Hibiscus malacospermus
Hibiscus martianus—Heartleaf Rosemallow
Hibiscus moscheutos Welw. ex Hiern.—Crimsoneyed Rosemallow (Central and Eastern North America)
Hibiscus mutabilis L.—Cotton Rosemallow, Confederate Rose (East Asia)
Hibiscus paramutabilis
Hibiscus pedunculatus
Hibiscus pernambucensis—Seaside Mahoe
Hibiscus phoeniceus—Brazilian Rosemallow
Hibiscus platanifolius
Hibiscus quattenensis
Hibiscus poeppigii—Poeppig's Rosemallow
Hibiscus radiatus—Monarch Rosemallow
Hibiscus rosa-sinensis L.—Chinese hibiscus (East Asia)
Hibiscus sabdariffa L.—Roselle, Omutete, or Sorrel
Hibiscus schizopetalus—Fringed Rosemallow
Hibiscus scottii
Hibiscus socotranus
Hibiscus sinosyriacus
Hibiscus splendens
Hibiscus stenanthus Balf.f. (Yemen)
Hibiscus striatus—Striped Rosemallow
Hibiscus syriacus L. (Type species)—Rose of Sharon (Asia)
Hibiscus tiliaceus L.—Sea hibiscus (Australia, Southeast Asia, Oceania)
Hibiscus trilobus—Threelobe Rosemallow
Hibiscus trionum L.—Flower-of-an-Hour
Hibiscus vitifolius—Tropical Rose Mallow
Hibiscus waimeae A.Heller—Kokiʻo keʻokeʻo (Hawaii)
MarketsandMarkets: Year 2008 Recorded Highest Number of Clinical Trials (10,326) during the Study Period (2007-2010)
The report "Global Clinical Trials Market (2007 - 2010)" analyses the total number of clinical trials conducted globally from 2007 to 2010 by phases, study design, indications, and major market drivers, restraints, and opportunities for the clinical trials market in North America, South America, Europe, and Asia.
Browse market data tables and in-depth TOC on Global Clinical Trials Market (2007 - 2010)
www.marketsandmarkets.com/Market-Reports/clinical-trials-...
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Clinical trials market now witness a paradigm shift. Naïve heterogeneous patient populations in the developing nations are opening up new avenues for the clinical trials market. Developing countries also offer faster go to market which is triggering major pharmaceutical companies to direct their investment in these regions. Apart from this, stringent regulations and tight R&D budgets in the Pharma-Biotech industry are also forcing companies to move to east. This scenario has further boosted the alliances between the pharma-biotech companies and the clinical research organizations, with the latter accounting for major chunk of the trials conducted.
Today, emerging countries account for the largest share of the phase II/III (prime stages) clinical trials conducted globally with major focus on oncology, Alzheimer’s, metabolic and cardiovascular diseases. Support from the respective government bodies is one of the major factors affecting the clinical trials market. Clinical trials sponsored by the industry have a much higher share in the market as compared to government organizations.
The key players (Clinical Research Organizations) in the market include Chiltern, Omnicare, PPD, Parexel, Kendle and Quintles.
The global clinical trials conducted in the year 2008 were reported to be 10,326 and were highest from 2007 to 2010. Oncology trials were the most widely conducted clinical trials accounting for 28.47% of all the trials conducted for the year 2008. Asia reported to a steady growth as compared to other regions which showed decline in the total number of clinical trials in the year 2010.
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