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Race for Life, Southampton 2009.

© All rights reserved

Open Gardens Weekend, Hatfield in aid of Cancer Research.

This image is the copyright of Mark Crawshaw. Copying this image is illegal.

Former Stagecoach Southdown GX59 JYT, a Scania N230UD Alexander Dennis Enviro 400 is pictured in the Northwood estate in Liverpool operating a 21 Service.

 

15586 has, for some time now, sported this Pink and Purple livery for Cancer Research UK.

DES Daughters

From left to right: Cheryl Roth, Caitlin McCarthy, Andrea Goldstein.

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

www.ginoandsharonphotography.co.uk/RACE-FOR-LIFE/

Today our aim was to capture the emotions at this beautiful event. Our thanks to everyone who took part. All our photos sold from this set we will donate all our profits to Cancer Research. Please help us support make a difference so if you see your friends in this album please send them the link. We were at 4 locations and we tried to get everyone who took part so please please please buy a print or download a photo ... Thank you so much... Gino and Sharon

Incredible efforts from everyone involved in the Swansea twilight race for life last Saturday evening. Extremely tough conditions. (Particular congratulations to hungry boyfriends standing in the wet and cold). Facebook | Twitter | Website | Blog | Pinterest | Google+ | Weddings | Arrows

British Freestyle Championship 2016 British Jetski Championship The Finals, Round 6 Lakeside Lake Doncaster South Yorkshire 04 September 2016 #JSRA #Finals www.networkimages.co.uk

I went to a Melanoma Symposium January 21. Tried to sketch on location, but I needed to concentrate on the presentations. Came home and googled images of the presenters. I was too scared to just sketch in my journal so I sketched on pieces of paper and later sewed the into my book. The concept is that I can flip the portraits and write notes on the talks and still see the Doctor's name below. I want to get on with these pages but feel hesitant about text and what I want to do... So I did the text on tissue paper and scanned the spreads. There you have it. Work in progress or not....There were lots of cool illustrated diagrams of how immunotherapy works. Might try some (or not)

Researchers at the University of North Carolina at Chapel Hill, Carolina Center of Cancer Nanotechnology Excellence (CCNE) are synthesizing particles that mimic red blood cells (RBCs) using a technology called PRINT (Particle Replication In Non-wetting Templates). These red blood cell mimics (RBCMs) have the same size, shape, and softness of true RBCs. The squishy microparticles can easily deform from their original disc-like shapes into irregular shapes when densely packed. The soft and squishy nature of the particles enables them to serve as hemoglobin carriers, creating new possibilities for delivering oxygen and creating blood substitutes. In addition to RBCMs, researchers are using PRINT to create nanoparticles for novel cancer treatments.

 

This image is part of the Nanotechnology Image Library collection.

 

Credit: Kai Chen and Joseph DeSimone, Ph.D., National Cancer Institute, National Institutes of Health

  

Red Arrows were definately going to cross the finish first

Left: MRI scans of a woman with breast cancer before TIL therapy show a lesion invading the chest wall (top) and metastatic lesions in the liver (bottom). Right: Scans 14 months after treatment show all lesions have disappeared.

 

A novel approach to immunotherapy developed by researchers at the National Cancer Institute (NCI) has led to the complete regression of breast cancer in a patient who was unresponsive to all other treatments. This patient received the treatment in a clinical trial led by Steven A. Rosenberg, M.D., Ph.D., chief of the Surgery Branch at NCI’s Center for Cancer Research (CCR), and the findings were published June 4, 2018 in Nature Medicine.

More info: www.nih.gov/news-events/news-releases/new-approach-immuno...

 

Credit: National Cancer Institute/NIH

  

Anne-Françoise Lof in her beautifully written book “Saskia or the mourning of a Distilbène baby” tells the sad story of her baby daughter born too early to survive at 22 weeks pregnancy. Anne-Françoise knew her mum had been prescribed Distilbène® during pregnancy, she warned her doctor. Yet, the high risk of premature labor was dismissed. The story of not only Saskia but many other premature babies shows the tragic consequences of some doctors’ misinformation and dismissive attitude towards diethylstilbestrol.

 

Anne-Françoise Lof

 

Distilbène®

 

Distilbène® sur Scoop it

 

Distilbène® sur YouTube

The 40th anniversary of the DES cancer link, April 2011, has triggered a flurry of press coverage. The Boston Globe ran a feature story about concerns for third generation effects; WCVB-TV Boston’s “Chronicle” newsmagazine aired a DES segment; Reuters published an item about DES Grandsons; New England Journal of Medicine ran an article about living with DES exposure; and Psychology Today features a story about remembering DES’s “tragic chapter in American childbirth.” Even the old “Lou Grant” TV episode about DES is making the rounds on Hulu

 

Photo courtesy of DES Info

 

DES Cancer Link 40th Anniversary

Baldies Unite!

 

Mau's 6-year old cousin Hannah has been suffering from cancer since she was 4 years old. This is a photo I took in our dining room for his Facebook link, him having shaven his head tonight to get sponsors for Cancer Research for Kids.

 

From this link,

www.stbaldricks.org/events/mypage/10830/2014,

scroll down to the bottom and watch the video to see Little Hannah and what these guys are doing in the Caymans to raise all this money.

 

Anyone interested in donating to this very worthy cause, here is a link to "The Big Shave" website where you may make a donation towards the St Baldrick's Foundation for Cancer Research for Children. All you need to do is click on the Donate Button and add your details.

www.stbaldricks.org/participants/mypage/734559/2014

 

Lastly, the St. Baldrick's Foundation is a volunteer-driven charity that funds more in childhood cancer research grants than any organization except the U.S. government. St Baldrick's (obviously a humorous name to lighten the mood) spends 87% of donations received on actual research meaning only a small percentage goes to overheads and Admin. Good thing ...

  

On May 1, 2018, Rhode Island Senator Jack Reed visited the NIH and toured Dr. Jack Shern's research lab. Dr. Shern provided an overview of his research on childhood cancer genomics and a demonstration of a device he and his team designed to perform single cell analysis to study relapsed disease, in an effort to identify specific cell characteristics driving therapy resistance and relapse.

 

Credit: National Institutes of Health

Picture by Mark Fletcher

 

The Race for Life

Seaton Carew, Hartlepool

Sunday 24th June 2012

David M. Boruta, II, MD (Division of Gynecologic Oncology), Clear Cell Carcinoma of the Vagina in DES Exposed Women.

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

It is still not known how many people are DES exposed worldwide. Many people remain unaware of their exposure and the potential adverse health effects of diethylstilbestrol. Many don’t make the link between DES exposure and the health problems they are facing and sometimes even doctors don’t make that link either.

 

Anyone born or pregnant in the US between 1938 and 1971, and until the mid-’80s in some European countries (until 1977 in France), may have been exposed. In the United States alone an estimated 5 -10 million people were exposed to Diethylstilbestrol, including women who were prescribed DES while pregnant, and the children born of those pregnancies.

 

On a pro rata basis with research done in the Netherlands and in America, the total number of people exposed to Diethylstilboestrol in the UK may be as high as 300,000. An estimated 200,000 French mothers have been prescribed DES and have given birth to 160,000 DES exposed daughters and sons. For Australia, an estimated 740,000 individuals have been DES exposed. DES has been and still is a well kept secret, a taboo subject not only in families but within the medical community too.

 

Diethylstilbestrol

ThomasToth MD Division Reproductive Endocrinology Infertility

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

2016 British Jetski Championship The Finals, Round 6 Lakeside Lake Doncaster South Yorkshire 04 September 2016 #JSRA #Finals www.networkimages.co.uk

wear boots and hats. and jeans. and button-down collared shirts. and they support cancer research!

Top of Carruntoohill and nearly at the end of a 5 peak challenge. 5 mountains in 62 hours......all for cancer research

The ability of cancer cells to move and spread depends on actin-rich core structures such as the podosomes (yellow) shown here in melanoma cells. Cell nuclei (blue), actin (red), and an actin regulator (green) are also shown.

 

This image was originally submitted as part of the 2015 NCI Cancer Close Up project and selected for exhibit.

 

See also visualsonline.cancer.gov/closeup

 

Credit: Julio C. Valencia, NCI Center for Cancer Research

MGH Poster Advertising DES Symposium

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

As tumors grow, they outpace the surrounding blood vessels' ability to provide enough oxygen, a state known as hypoxia. Rather than killing the tumor, however, hypoxia triggers changes in cancer cell metabolism that actually promote tumor growth and spread. Understanding more about hypoxia in cancer cells may help researchers find better ways of managing the disease. This image of a mouse model for HER2-positive breast cancer uses a novel imaging technique called transparent tumor tomography that three-dimensionally visualizes the tumor microenvironment at a single cell resolution. Hypoxic areas are in green; HER2 proteins in blue; CD31 endothelial cells in red.

 

This image was originally submitted as part of the 2016 NCI Cancer Close Up project.

 

See also visualsonline.cancer.gov/closeup2016.

 

Credit: Steve Seung-Young Lee, Univ. of Chicago Comprehensive Cancer Center, National Cancer Institute, National Institutes of Health

Tumor angiogenesis (the exploitation of healthy cells to form new blood vessels) is a vital area of cancer research.

 

The two-panel image above shows one such promising lead from recent lab studies with endothelial cells, specialized cells that line the inside of all blood vessels. In tumors, endothelial cells are induced to issue non-stop SOS signals that falsely alert the body to dispatch needed materials to rescue these cells. The endothelial cells then use the help to replicate and sprout new blood vessels.

 

The left panel demonstrates the basics of this growth process under normal conditions. Endothelial cells (red and blue) were cultured under special conditions that help them grow in the lab. When given the right cues, those cells sprout spiky extensions to form new vessels.

 

But in the right panel, the cells can’t sprout. The reason is because the cells are bathed in a molecule called miR-30c, which isn’t visible in the photo. These specialized microRNA molecules—and humans make a few thousand different versions of them—control protein production by binding to and disabling longer RNA templates, called messenger RNA.

 

Read more: directorsblog.nih.gov/2019/09/05/using-microrna-to-starve...

 

Credit: Dudley Lab, University of Virginia School of Medicine, Charlottesville

 

NIH support from: National Cancer Institute; National Heart, Lung, and Blood Institute

Most tumors are made up of many different types of cancer cells (tumor heterogeneity), which often harbor unique genetic mutations. Researchers want to identify how different subgroups of cancer cells within a tumor affect the ability of cancer cells to metastasize or develop resistance to therapeutic agents. This image of a mouse model of pancreatic cancer shows multi-color lineage tracing ("confetti") and demonstrates that a sizeable number of metastases arise from heterogeneous cell clusters rather than the outgrowth of single cells.

 

This image was originally submitted as part of the 2016 NCI Cancer Close Up project and selected for exhibit.

 

See also

visualsonline.cancer.gov/closeup2016.

 

Credit: Ravikanth Maddipati, Abramson Cancer Center at the Univ. of Pennsylvania, National Cancer Institute, National Institutes of Health

 

The image shows a hematoxylin and Eosin (H&E) stain of a liver section belonging to an NSG mouse with metastatic infiltrate. Hepatocytes on lower left of image, with a mass of endothelial cells extravasating into the liver tissue from the upper right. Examining the response of the EC-infiltrated tissue and the overall health of the animal allows us to better understand the clinical implications of KS metastasis and target potential treatments. 200X magnification.

 

This image was chosen as a winner of the 2016 NIH funded research image call.

 

Credit: Imaging/tissue extraction by Anthony B. Eason; lab of Dirk Dittmer, University of North Carolina Lineberger Comprehensive Cancer Center. Mice maintained by UNC Animal Studies Core; staining by UNC Animal Histopathology Core.

 

This image is not owned by the NIH. It is shared with the public under license. If you have a question about using or reproducing this image, please contact the creator listed in the credits. All rights to the work remain with the original creator.

 

NIH funding from: National Cancer Institute (NCI)

 

From left to right: Andrea Goldstein, Caitlin McCarthy, and Cheryl Roth.

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

www.ginoandsharonphotography.co.uk/RACE-FOR-LIFE/

Today our aim was to capture the emotions at this beautiful event. Our thanks to everyone who took part. All our photos sold from this set we will donate all our profits to Cancer Research. Please help us support make a difference so if you see your friends in this album please send them the link. We were at 4 locations and we tried to get everyone who took part so please please please buy a print or download a photo ... Thank you so much... Gino and Sharon

Recently my nieces posted their 'no make-up selfies' online in aid of Cancer Research. Holding a tablespoon in one hand and trying to photograph with the XF 60mm macro lens attached to the X-Pro1 in the other wasn't easy. But, I managed it after a few attempts and here's the result. By the way that's me in the bowl of the spoon. Just a bit of creative fun :)

#nomakeupselfie has seen thousands go bare-faced online, and over one million raised for Cancer Research. Visit www.cruk.org to give your support.

5/27/09 - Dana Delany, Charles Gibson and Dr. William Nelson give an update on fundraising efforts marking the one year anniversary of "Stand Up To Cancer," on GOOD MORNING AMERICA. GM09 (ABC/ Ida Mae Astute).

 

(L to R) DIANE SAWYER, DANA DELANY, CHARLES GIBSON, DR. WILLIAM NELSON

Caitlin McCarthy, DES Daughter and screenwriter of WONDER DRUG (www.wonderdrugthemovie.com), an award-winning screenplay about the DES drug disaster.

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

Rhode Island Senator Jack Reed visits with a pediatric cancer patient in the Pediatric Oncology Branch at NIH on May 1, 2018. The 13 year old patient, Scarlett, is participating in a targeted immunotherapy clinical trial for children with relapsed or refractory leukemias and lymphomas.

 

Credit: National Institutes of Health

John Schorge DES Symposium Moderator MGH MD Chief Gynecology Oncology.

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

Issaac Schiff MD Chief MGH Vincent Department Obstetrics Gynecology

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

Cancer that has spread (metastasized) to the brain is normally untreatable because the protective blood-brain barrier blocks entry of most therapeutics. Nanoparticles capable of carrying drugs and "hitchhiking" across the barrier may allow the delivery of life-saving therapies to these tumors. This image shows blood vessels (red), cell nuclei (blue), and human metastatic breast cancer cells (green) in a mouse's brain, after intravenous administration of experimental nanoparticles that can cross the blood-brain barrier.

 

Credit: Emily Wyatt, Mark Davis, California Institute of Technology

 

NIH funding from: National Cancer Institute

DES Symposium Reception

 

On May 19th 2011, the Massachusetts General Hospital (MGH) in Boston, Massachusetts, USA hosted a DES (Diethylstibestrol) symposium. DES daughters shared their experiences and discussed with DES specialists the lessons learned about embryogenesis, fertility, and carcinogenesis from in utero exposures. The DES symposium was free and open to the general public.

 

Photo courtesy of DES Info

 

2011 DES (Diethylstilbestrol) Symposium, MGH Boston, USA

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