View allAll Photos Tagged segmentation
(www.adgorithms.com) - A research has proven how performance advertising had gained results and revenues to advertisers. According to a Jupiter research, by year 2012, it is predicted that the United States of America will more likely spend $34.5 billion in performance advertising.
20. November 2019, Jugendstilhörsaal der MedUni Wien
“Multiparametic Diagnostics and Theranostics of Tumors”
Fabian Kiessling, Universitätsklinikum Aachen
Abstract:
Significant advances have been achieved in elucidating molecular regulations of cancer and numerous disease-related markers were identified. Additionally, imaging technologies steadily improved and are providing detailed insight into tissues’ morphology, function and molecular regulation. However, there is still a need to identify and quantify the most relevant information and to bring it into a mechanistic context.
In the first part of my talk, I present advanced imaging strategies to characterize tumors by assessing various “hallmarks of cancer” using non-invasive imaging and to assess therapy responses. In this context, I will discuss novel computer applications to improve data processing, lesion detection and segmentation as well as radiomic image analysis. However, taking a study on hepatocellular carcinoma therapy with a multispecific tyrosine kinase inhibitor as an example, I will also show that correlative analyses do not always lead to correct conclusions on biological mechanisms and that the interconnection and impact of the observed changes need to be understood.
The second part of my talk will be dedicated to drug delivery. Here, I will show how imaging can be used to improve the preselection of patients to therapies and discuss the value of nanomedicines and active targeting. Furthermore, I will highlight the potential of ultrasound mediated theranostics to overcome biological barriers and to improve tumor perfusion.
(c) MedUni Wien / Kovic
(www.adgorithms.com) - In performance advertising, it can be customized. These include the content and the websites. Here are a few examples:
•AdWords
•Yahoo Search Marketing
•Google AdSense
Segmentation is all about breaking up a large consumer market into smaller parts on the basis of consumers’ needs and characteristics. This process of breaking up, eventually exposes companies to their market opportunities.
models-los-angeles.blogspot.com/2012/11/modern-business-m...
Today is my 2nd day on leave in preparation for my Marketing paper tml (27 Sep). While I was about to pick up my lecture notes on 'Segmentation of the Market' (as you can see the S on the far right),
I found a decomposed bug....looks like a flying ant..'Wasp' ? Not sure..
Ok...Back to the paper "Segmentation of the Market".
www.shoprusher.com/pants/187000521,2012-winter-new-leisur...
2012 Winter New Leisure Cotton Segmentation Splice Shorts 823094395
Overall the forum was a huge success. Our companies were able to get answers to their questions about market segmentation as well as a set of actionable next steps.
Learn More about the Marketing Segmentation Forum: openviewpartners.com/event/market-segmentation-forum/
20. November 2019, Jugendstilhörsaal der MedUni Wien
“Multiparametic Diagnostics and Theranostics of Tumors”
Fabian Kiessling, Universitätsklinikum Aachen
Abstract:
Significant advances have been achieved in elucidating molecular regulations of cancer and numerous disease-related markers were identified. Additionally, imaging technologies steadily improved and are providing detailed insight into tissues’ morphology, function and molecular regulation. However, there is still a need to identify and quantify the most relevant information and to bring it into a mechanistic context.
In the first part of my talk, I present advanced imaging strategies to characterize tumors by assessing various “hallmarks of cancer” using non-invasive imaging and to assess therapy responses. In this context, I will discuss novel computer applications to improve data processing, lesion detection and segmentation as well as radiomic image analysis. However, taking a study on hepatocellular carcinoma therapy with a multispecific tyrosine kinase inhibitor as an example, I will also show that correlative analyses do not always lead to correct conclusions on biological mechanisms and that the interconnection and impact of the observed changes need to be understood.
The second part of my talk will be dedicated to drug delivery. Here, I will show how imaging can be used to improve the preselection of patients to therapies and discuss the value of nanomedicines and active targeting. Furthermore, I will highlight the potential of ultrasound mediated theranostics to overcome biological barriers and to improve tumor perfusion.
(c) MedUni Wien / Kovic
Majin Buu was one of the final villains introduced in the Dragonball Z series, and main reason for everyone powering up again. His most famous form in this arc is that of Innocent Buu, which is the pink blob.. which also appears to be his look when he's split up into Good Buu and Kid Buu.... anyway.
Despite his childlike appearance and behavior, he's one of the most horrific beings to ever exist (at that time, of course... everyone is always the worst thing ever when they're introduced), only held back as it were by some influence of a Grand Kai that was absorbed earlier in his existence. He's basically Kirby if he went rogue.
The character is of course represented in Figuarts form.
As the Dragonball releases general scale to each other, Buu is gigantic, not quite reaching Broly size, but pretty close, and dwarfs all of the other Z fighters. Being an extremely large figure, Buu is definitely more hollow as compared to his smaller peers, most notably in the body itself. Some of this is for the better, as that is where the guts of this articulation is hidden.
It's just unfortunate the younger generation will never know the joys of beating the shit out of your friends with 10 inch rubber WWF figures.
Buu comes with 3 heads, with I believe a bonus "Good Buu" head with the upcoming Kid Buu Figuarts. No stand and relatively few hands, but he does come with his trademark chocolate bar, which apparently if he's Innocent Buu is probably someone transformed into food, or if he's Good Buu it's literally a chocolate bar as he can't absorb people anymore.
All I know is he eats no matter where he goes.
In addition to the aforementioned, you will also notice he has his trademark purple cape, slightly poseable due to the segmentation. It's not as poseable as say, the Batman ones from Play Arts, but it also doesn't look anywhere as hideous so... winning?
Colours are nice and sharp, much like on Gotenks. I don't know how things are like on other Figuarts lines, but it does seem like Bandai has gotten their act together at least on the Dragonball stuff. Of course, given its premium status, it's kind of necessary.
Articulation is pretty good too. It's not quite Storm Collectibles Zangief good, but it's on part with Broly, meaning the only real thing missing is an upper chest joint. As mentioned, hollow cavities allow for joint placements that increase his range of movement. Of course, due to his size, the actual poses Buu can hold without additional support are kind of limited though I don't exactly recall him being a super limber kind of guy. A standard figure stand won't support him, so if you want to do any mid air posing, you're going to need to find something more robust, or get creative.
While they're all memorable characters, you got to admit in a line where more than half of them seem to basically be a bipedal humanoid with two arms that share the same workout routine, it's the aliens and other seemingly random characters that stick out on your shelves. Majin Buu is no exception - I think he makes a great accent piece in your Figuarts sized collection, regardless if its Dragonball or not.
Much like with Broly, Buu is large and in charge and is a great addition to your set, but I wouldn't go in expecting him to be a posing dynamo, which is usually the case with larger figures (except for Storm Zangief), though really I feel the only point missing would be an articulation point at the chest.
Fragments of Self
This piece is from a body of work entitled "Fragments of Self", created in response to the artist’s experience with an undiagnosed chronic illness. It reflects on the challenge of fighting for health despite simultaneously feeling betrayed by her body. She was heavily influenced by her experience of conceptualizing certain parts of her body as "functional" versus "broken," and the struggle to feel a sense of connectedness between her body’s physical dysfunction and her mental desire for health. In manipulating the printed self-portraits, the artist's process and work serve as a metaphor for the emotional sense of segmentation experienced throughout her illness, and parallel the iterative process of self-healing.
sophiepellegrini1@gmail.com
Majin Buu was one of the final villains introduced in the Dragonball Z series, and main reason for everyone powering up again. His most famous form in this arc is that of Innocent Buu, which is the pink blob.. which also appears to be his look when he's split up into Good Buu and Kid Buu.... anyway.
Despite his childlike appearance and behavior, he's one of the most horrific beings to ever exist (at that time, of course... everyone is always the worst thing ever when they're introduced), only held back as it were by some influence of a Grand Kai that was absorbed earlier in his existence. He's basically Kirby if he went rogue.
The character is of course represented in Figuarts form.
As the Dragonball releases general scale to each other, Buu is gigantic, not quite reaching Broly size, but pretty close, and dwarfs all of the other Z fighters. Being an extremely large figure, Buu is definitely more hollow as compared to his smaller peers, most notably in the body itself. Some of this is for the better, as that is where the guts of this articulation is hidden.
It's just unfortunate the younger generation will never know the joys of beating the shit out of your friends with 10 inch rubber WWF figures.
Buu comes with 3 heads, with I believe a bonus "Good Buu" head with the upcoming Kid Buu Figuarts. No stand and relatively few hands, but he does come with his trademark chocolate bar, which apparently if he's Innocent Buu is probably someone transformed into food, or if he's Good Buu it's literally a chocolate bar as he can't absorb people anymore.
All I know is he eats no matter where he goes.
In addition to the aforementioned, you will also notice he has his trademark purple cape, slightly poseable due to the segmentation. It's not as poseable as say, the Batman ones from Play Arts, but it also doesn't look anywhere as hideous so... winning?
Colours are nice and sharp, much like on Gotenks. I don't know how things are like on other Figuarts lines, but it does seem like Bandai has gotten their act together at least on the Dragonball stuff. Of course, given its premium status, it's kind of necessary.
Articulation is pretty good too. It's not quite Storm Collectibles Zangief good, but it's on part with Broly, meaning the only real thing missing is an upper chest joint. As mentioned, hollow cavities allow for joint placements that increase his range of movement. Of course, due to his size, the actual poses Buu can hold without additional support are kind of limited though I don't exactly recall him being a super limber kind of guy. A standard figure stand won't support him, so if you want to do any mid air posing, you're going to need to find something more robust, or get creative.
While they're all memorable characters, you got to admit in a line where more than half of them seem to basically be a bipedal humanoid with two arms that share the same workout routine, it's the aliens and other seemingly random characters that stick out on your shelves. Majin Buu is no exception - I think he makes a great accent piece in your Figuarts sized collection, regardless if its Dragonball or not.
Much like with Broly, Buu is large and in charge and is a great addition to your set, but I wouldn't go in expecting him to be a posing dynamo, which is usually the case with larger figures (except for Storm Zangief), though really I feel the only point missing would be an articulation point at the chest.
Majin Buu was one of the final villains introduced in the Dragonball Z series, and main reason for everyone powering up again. His most famous form in this arc is that of Innocent Buu, which is the pink blob.. which also appears to be his look when he's split up into Good Buu and Kid Buu.... anyway.
Despite his childlike appearance and behavior, he's one of the most horrific beings to ever exist (at that time, of course... everyone is always the worst thing ever when they're introduced), only held back as it were by some influence of a Grand Kai that was absorbed earlier in his existence. He's basically Kirby if he went rogue.
The character is of course represented in Figuarts form.
As the Dragonball releases general scale to each other, Buu is gigantic, not quite reaching Broly size, but pretty close, and dwarfs all of the other Z fighters. Being an extremely large figure, Buu is definitely more hollow as compared to his smaller peers, most notably in the body itself. Some of this is for the better, as that is where the guts of this articulation is hidden.
It's just unfortunate the younger generation will never know the joys of beating the shit out of your friends with 10 inch rubber WWF figures.
Buu comes with 3 heads, with I believe a bonus "Good Buu" head with the upcoming Kid Buu Figuarts. No stand and relatively few hands, but he does come with his trademark chocolate bar, which apparently if he's Innocent Buu is probably someone transformed into food, or if he's Good Buu it's literally a chocolate bar as he can't absorb people anymore.
All I know is he eats no matter where he goes.
In addition to the aforementioned, you will also notice he has his trademark purple cape, slightly poseable due to the segmentation. It's not as poseable as say, the Batman ones from Play Arts, but it also doesn't look anywhere as hideous so... winning?
Colours are nice and sharp, much like on Gotenks. I don't know how things are like on other Figuarts lines, but it does seem like Bandai has gotten their act together at least on the Dragonball stuff. Of course, given its premium status, it's kind of necessary.
Articulation is pretty good too. It's not quite Storm Collectibles Zangief good, but it's on part with Broly, meaning the only real thing missing is an upper chest joint. As mentioned, hollow cavities allow for joint placements that increase his range of movement. Of course, due to his size, the actual poses Buu can hold without additional support are kind of limited though I don't exactly recall him being a super limber kind of guy. A standard figure stand won't support him, so if you want to do any mid air posing, you're going to need to find something more robust, or get creative.
While they're all memorable characters, you got to admit in a line where more than half of them seem to basically be a bipedal humanoid with two arms that share the same workout routine, it's the aliens and other seemingly random characters that stick out on your shelves. Majin Buu is no exception - I think he makes a great accent piece in your Figuarts sized collection, regardless if its Dragonball or not.
Much like with Broly, Buu is large and in charge and is a great addition to your set, but I wouldn't go in expecting him to be a posing dynamo, which is usually the case with larger figures (except for Storm Zangief), though really I feel the only point missing would be an articulation point at the chest.
Segmentation board game
A hands-on, interactive game that allows stakeholders to engage and empathise with their target customers by putting segments into real life situations to explore different scenarios and contexts.
20. November 2019, Jugendstilhörsaal der MedUni Wien
“Multiparametic Diagnostics and Theranostics of Tumors”
Fabian Kiessling, Universitätsklinikum Aachen
Abstract:
Significant advances have been achieved in elucidating molecular regulations of cancer and numerous disease-related markers were identified. Additionally, imaging technologies steadily improved and are providing detailed insight into tissues’ morphology, function and molecular regulation. However, there is still a need to identify and quantify the most relevant information and to bring it into a mechanistic context.
In the first part of my talk, I present advanced imaging strategies to characterize tumors by assessing various “hallmarks of cancer” using non-invasive imaging and to assess therapy responses. In this context, I will discuss novel computer applications to improve data processing, lesion detection and segmentation as well as radiomic image analysis. However, taking a study on hepatocellular carcinoma therapy with a multispecific tyrosine kinase inhibitor as an example, I will also show that correlative analyses do not always lead to correct conclusions on biological mechanisms and that the interconnection and impact of the observed changes need to be understood.
The second part of my talk will be dedicated to drug delivery. Here, I will show how imaging can be used to improve the preselection of patients to therapies and discuss the value of nanomedicines and active targeting. Furthermore, I will highlight the potential of ultrasound mediated theranostics to overcome biological barriers and to improve tumor perfusion.
(c) MedUni Wien / Kovic
Sand dollars (also known as sea cookies or snapper biscuits in New Zealand and Brazil, or pansy shells in South Africa) are species of flat, burrowing sea urchins belonging to the order Clypeasteroida. Some species within the order, not quite as flat, are known as sea biscuits. Sand dollars can also be called "sand cakes" or "cake urchins".[2]
Names
The term "sand dollar" derives from the appearance of the tests (skeletons) of dead individuals after being washed ashore. The test lacks its velvet-like skin of spines and has often been bleached white by sunlight. To beachcombers of the past, this suggested a large, silver coin, such as the old Spanish dollar, which had a diameter of 38–40 mm.
Other names for the sand dollar include sand cakes, pansy shells, snapper biscuits, cake urchins, and sea cookies.[3] In South Africa, they are known as pansy shells from their suggestion of a five-petaled garden flower. The Caribbean sand dollar or inflated sea biscuit, Clypeaster rosaceus, is thicker in height than most. In Spanish-speaking areas of the Americas, the sand dollar is most often known as galleta de mar (sea cookie); the translated term is often encountered in English.
In the folklore of Georgia in the United States, sand dollars were believed to represent coins lost by mermaids.[4]
Description
Leodia sexiesperforata by Louis Agassiz (1841)
Examples of Rotulidae
Encope emarginata (aboral and oral faces) by Ernst Haeckel (1904)
Clypeaster rosaceus (aboral and oral faces) by Ernst Haeckel (1904)
Sand dollars diverged from the other irregular echinoids, namely the cassiduloids, during the early Jurassic,[5] with the first true sand dollar genus, Togocyamus, arising during the Paleocene. Soon after Togocyamus, more modern-looking groups emerged during the Eocene.[1]
Sand dollars are small in size, averaging from three to four inches.[6] As with all members of the order Clypeasteroida, they possess a rigid skeleton called a test. The test consists of calcium carbonate plates arranged in a fivefold symmetric pattern.[7] The test of certain species of sand dollar have slits called lunules that can help the animal stay embedded in the sand to stop it from being swept away by an ocean wave.[8] In living individuals, the test is covered by a skin of velvet-textured spines which are covered with very small hairs (cilia). Coordinated movements of the spines enable sand dollars to move across the seabed. The velvety spines of live sand dollars appear in a variety of colors—green, blue, violet, or purple—depending on the species. Individuals which are very recently dead or dying (moribund) are sometimes found on beaches with much of the external morphology still intact. Dead individuals are commonly found with their empty test devoid of all surface material and bleached white by sunlight.
The bodies of adult sand dollars, like those of other echinoids, display radial symmetry. The petal-like pattern in sand dollars consists of five paired rows of pores. The pores are perforations in the endoskeleton through which podia for gas exchange project from the body. The mouth of the sand dollar is located on the bottom of its body at the center of the petal-like pattern. Unlike other urchins, the bodies of sand dollars also display secondary front-to-back bilateral symmetry with no morphological distinguishing features between males and females. The anus of sand dollars is located at the back rather than at the top as in most urchins, with many more bilateral features appearing in some species. These result from the adaptation of sand dollars, in the course of their evolution, from creatures that originally lived their lives on top of the seabed (epibenthos) to creatures that burrow beneath it (endobenthos).
Echinocyamus pusillus alive.
Echinocyamus pusillus alive.
Living sand dollar.
Living sand dollar.
Eccentric sand dollars (Dendraster excentricus) at Monterey Bay Aquarium.
Eccentric sand dollars (Dendraster excentricus) at Monterey Bay Aquarium.
Echinarachnius parma (family Echinarachniidae).
Echinarachnius parma (family Echinarachniidae).
Mellita quinquiesperforata test (Clypeasteridae)
Mellita quinquiesperforata test (Clypeasteridae)
Clypeaster reticulatus test (Clypeasteridae)
Clypeaster reticulatus test (Clypeasteridae)
Echinodiscus tenuissimus test (Astriclypeidae)
Echinodiscus tenuissimus test (Astriclypeidae)
Clypeaster aegypticus, showing internal buttresses
Clypeaster aegypticus, showing internal buttresses
Suborders and families
According to World Register of Marine Species:
sub-order Clypeasterina
family Clypeasteridae L. Agassiz, 1835
family Fossulasteridae Philip & Foster, 1971 †
family Scutellinoididae Irwin, 1995 †
family Conoclypidae von Zittel, 1879 †
family Faujasiidae Lambert, 1905 †
family Oligopygidae Duncan, 1889 †
family Plesiolampadidae Lambert, 1905 †
sub-order Scutellina
infra-order Laganiformes
family Echinocyamidae Lambert & Thiéry, 1914
family Fibulariidae Gray, 1855
family Laganidae Desor, 1858
infra-order Scutelliformes
family Echinarachniidae Lambert in Lambert & Thiéry, 1914
family Eoscutellidae Durham, 1955 †
family Protoscutellidae Durham, 1955 †
family Rotulidae Gray, 1855
super-family Scutellidea Gray, 1825
family Abertellidae Durham, 1955 †
family Astriclypeidae Stefanini, 1912
family Dendrasteridae Lambert, 1900 -- Pacific eccentric sand dollar.
family Mellitidae Stefanini, 1912 -- Keyhole sand dollars
family Monophorasteridae Lahille, 1896 †
family Scutasteridae Durham, 1955 †
family Scutellidae Gray, 1825
family Taiwanasteridae Wang, 1984
family Scutellinidae Pomel, 1888a †
Underside of live Mellita quinquiesperforata
Underside of live Mellita quinquiesperforata
A number of sand dollars on the seabed
A number of sand dollars on the seabed
Sand dollar beneath the sand at low tide on Hilton Head Island
Sand dollar beneath the sand at low tide on Hilton Head Island
Live sea biscuit, Clypeaster rosaceus, commonly found off Key Biscayne, Florida
Live sea biscuit, Clypeaster rosaceus, commonly found off Key Biscayne, Florida
Behavior and habitat
A sand dollar digging into the sand on the Playa Novillero beach at low tide on the Pacific coast of Mexico
Spines on the underside of a sand dollar on the beach at Hilton Head Island, South Carolina
Sand dollars can be found in temperate and tropical zones along all continents.[6] Sand dollars live in waters below the mean low water line, on or just beneath the surface of sandy and muddy areas. The common sand dollar, Echinarachnius parma, can be found in the Northern Hemisphere from the intertidal zone to the depths of the ocean, while the keyhole sand dollars (three species of the genus Mellita) can be found on many a wide range of coasts in and around the Caribbean Sea.
The spines on the somewhat flattened topside and underside of the animal allow it to burrow or creep through the sediment when looking for shelter or food. Fine, hair-like cilia cover these tiny spines.[9] Sand dollars usually eat algae and organic matter found along the ocean floor, though some species will tip on their side to catch organic matter floating in ocean currents.[8]
Sand dollars frequently gather on the ocean floor, in part to their preference for soft bottom areas, which are convenient for their reproduction.[why?] The sexes are separate and, as with most echinoids, gametes are released into the water column and go through external fertilization. The nektonic larvae metamorphose through several stages before the skeleton or test begins to form, at which point they become benthic.
In 2008, biologists discovered that sand dollar larvae will clone themselves for a few different reasons. When a predator is near, certain species of sand dollar larvae will split themselves in half in a process they use to asexually clone themselves when sensing danger. The cloning process can take up to 24 hours and creates larvae that are 2/3 smaller than their original size which can help conceal them from the predator.[10] The larvae of these sand dollars clone themselves when they sense dissolved mucus from a predatory fish. The larvae exposed to this mucus from the predatory fish respond to the threat by cloning themselves. This process doubles their population and halves their size which allows them to better escape detection by the predatory fish but may make them more vulnerable to attacks from smaller predators like crustaceans. Sand dollars will also clone themselves during normal asexual reproduction. Larvae will undergo this process when food is plentiful or temperature conditions are optimal. Cloning may also occur to make use of the tissues that are normally lost during metamorphosis.
The flattened test of the sand dollar allows it to burrow into the sand and remain hidden from sight from potential predators.[8] Predators of the sand dollar are the fish species cod, flounder, sheepshead and haddock. These fish will prey on sand dollars even through their tough exterior.[9]
Sand dollars have spines on their bodies that help them to move around the ocean floor. When a sand dollar dies, it loses the spines and becomes smooth as the exoskeleton is then exposed.[11] Wikipedia. Barnacles are a type of arthropod constituting the subclass Cirripedia in the subphylum Crustacea,[1] and are hence related to crabs and lobsters. Barnacles are exclusively marine, and tend to live in shallow and tidal waters, typically in erosive settings. Around 1,000 barnacle species are currently known.[2]
They are sessile (nonmobile) and most are suspension feeders, but those in infraclass Rhizocephala are highly specialized parasites on other crustaceans. They have four nektonic (active swimming) larval stages.
Description
Whale barnacles attached to the throat of a humpback whale
Barnacles on a boat propeller.
Barnacles are encrusters, attaching themselves temporarily to a hard substrate or a symbiont such as a whale (whale barnacles), a sea snake (Platylepas ophiophila), or another crustacean, like a crab or a lobster (Rhizocephala). The most common among them, "acorn barnacles" (Sessilia), are sessile where they grow their shells directly onto the substrate.[3] Pedunculate barnacles (goose barnacles and others) attach themselves by means of a stalk.[3]
Attachment
Free-living barnacles are attached to the substratum by cement glands that form the base of the first pair of antennae; in effect, the animal is fixed upside down by means of its forehead. In some barnacles, the cement glands are fixed to a long, muscular stalk, but in most they are part of a flat membrane or calcified plate. These glands secrete a type of natural quick cement made of complex protein bonds (polyproteins) and other trace components like calcium.[4]: 2–3 This natural cement is able to withstand a pulling strength of 5,000 pounds-force per square inch (30,000 kilopascals; 400 kilograms-force per square centimetre) and a sticking strength of 22–60 pounds-force per square inch (200–400 kilopascals; 2–4 kilograms-force per square centimetre).[5]
A ring of plates surrounds the body, homologous with the carapace of other crustaceans. These consist of the rostrum, two lateral plates, two carinolaterals, and a carina.[6] In sessile barnacles, the apex of the ring of plates is covered by an operculum, which may be recessed into the carapace. The plates are held together by various means, depending on species, in some cases being solidly fused.[citation needed]
Inside body
Inside the carapace, the animal lies on its stomach, projecting its limbs downwards. Segmentation is usually indistinct, and the body is more or less evenly divided between the head and thorax, with little, if any, abdomen. Adult barnacles have few appendages on their heads, with only a single, vestigial pair of antennae, attached to the cement gland. The eight pairs of thoracic limbs are referred to as "cirri" which are feathery and very long. The cirri extend to filter food, such as plankton, from the water and move it towards the mouth.[5]
Barnacles have no true heart, although a sinus close to the esophagus performs a similar function, with blood being pumped through it by a series of muscles.[7] The blood vascular system is minimal. Similarly, they have no gills, absorbing oxygen from the water through their limbs and the inner membrane of their carapaces. The excretory organs of barnacles are maxillary glands.[citation needed]
The main sense of barnacles appears to be touch, with the hairs on the limbs being especially sensitive. The adult also has three photoreceptors (ocelli), one median and two lateral. These photoreceptors record the stimulus for the barnacle shadow reflex, where a sudden decrease in light causes cessation of the fishing rhythm and closing of the opercular plates.[8] The photoreceptors are likely only capable of sensing the difference between light and dark.[9] This eye is derived from the primary naupliar eye.[10]
Etymology
See also: Barnacle goose myth
The word "barnacle" is attested in the early 13th century as "bernekke" and originally referred to a species of goose. Because the full life cycles of both barnacles and geese was unknown at the time, (geese spend their breeding seasons in the Arctic) a folktale emerged that geese hatched from barnacles. It was not applied strictly to the invertebrate until the 1580s. The ultimate meaning of the word "barnacle" is unknown.[11][12]
Life cycle
Barnacles have two distinct larval stages, the nauplius and the cyprid, before developing into a mature adult.
Nauplius
Nauplius larva of Elminius modestus
Nauplius larva of a barnacle with fronto-lateral horns[13]
A fertilised egg hatches into a nauplius: a one-eyed larva comprising a head and a telson, without a thorax or abdomen. This undergoes six moults, passing through five instars, before transforming into the cyprid stage. Nauplii are typically initially brooded by the parent, and released after the first moult as larvae that swim freely using setae.[14][15]
Cyprid
The cyprid larva is the last larval stage before adulthood. In Rhizocephala and Thoracica an abdomen is absent in this stage, but the y-cyprids (post‐naupliar instar) has three distinct abdominal segments.[16] It is not a feeding stage; its role is to find a suitable place to settle, since the adults are sessile.[14] The cyprid stage lasts from days to weeks. It explores potential surfaces with modified antennules; once it has found a potentially suitable spot, it attaches head-first using its antennules and a secreted glycoproteinous substance. Larvae assess surfaces based upon their surface texture, chemistry, relative wettability, color, and the presence or absence and composition of a surface biofilm; swarming species are also more likely to attach near other barnacles.[17] As the larva exhausts its finite energy reserves, it becomes less selective in the sites it selects. It cements itself permanently to the substrate with another proteinaceous compound, and then undergoes metamorphosis into a juvenile barnacle.[17]
Adult
Typical acorn barnacles develop six hard calcareous plates to surround and protect their bodies. For the rest of their lives, they are cemented to the substrate, using their feathery legs (cirri) to capture plankton.
Once metamorphosis is over and they have reached their adult form, barnacles continue to grow by adding new material to their heavily calcified plates. These plates are not moulted; however, like all ecdysozoans, the barnacle itself will still moult its cuticle.[18]
Sexual reproduction
Most barnacles are hermaphroditic, although a few species are gonochoric or androdioecious. The ovaries are located in the base or stalk, and may extend into the mantle, while the testes are towards the back of the head, often extending into the thorax. Typically, recently moulted hermaphroditic individuals are receptive as females. Self-fertilization, although theoretically possible, has been experimentally shown to be rare in barnacles.[19][20]
The sessile lifestyle of barnacles makes sexual reproduction difficult, as the organisms cannot leave their shells to mate. To facilitate genetic transfer between isolated individuals, barnacles have extraordinarily long penises. Barnacles probably have the largest penis to body size ratio of the animal kingdom,[19] up to eight times their body length.[21]
Barnacles can also reproduce through a method called spermcasting, in which the male barnacle releases his sperm into the water and females pick it up and fertilise their eggs.[22][23]
The Rhizocephala superorder used to be considered hermaphroditic, but it turned out that its males inject themselves into the female's body, degrading to the condition of nothing more than sperm-producing cells.[24]
Ecology
Duration: 30 seconds.0:30
Semibalanus balanoides feeding
Most barnacles are suspension feeders; they dwell continually in their shells, which are usually constructed of six plates,[3] and reach into the water column with modified legs. These feathery appendages beat rhythmically to draw plankton and detritus into the shell for consumption.[25]
Other members of the class have quite a different mode of life. For example, members of the superorder Rhizocephala, including the genus Sacculina, are parasitic and live within crabs.[26]
Although they have been found at water depths to 600 m (2,000 ft),[3] most barnacles inhabit shallow waters, with 75% of species living in water depths less than 100 m (300 ft),[3] and 25% inhabiting the intertidal zone.[3] Within the intertidal zone, different species of barnacles live in very tightly constrained locations, allowing the exact height of an assemblage above or below sea level to be precisely determined.[3]
Since the intertidal zone periodically desiccates, barnacles are well adapted against water loss. Their calcite shells are impermeable, and they possess two plates which they can slide across their apertures when not feeding. These plates also protect against predation.[27]
One group of stalked barnacles have adapted to a rafting lifestyle, where they are drifting around close to the water's surface. They will colonize every floating object, such as driftwood, and like some non-stalked barnacles, also attach themselves to marine animals. The species most specialized for this lifestyle is Dosima fascicularis, which secretes a gas-filled cement that makes it float at the surface.[28]
Barnacles are displaced by limpets and mussels, which compete for space. They also have numerous predators.[3] They employ two strategies to overwhelm their competitors: "swamping" and fast growth. In the swamping strategy, vast numbers of barnacles settle in the same place at once, covering a large patch of substrate, allowing at least some to survive in the balance of probabilities.[3] Fast growth allows the suspension feeders to access higher levels of the water column than their competitors, and to be large enough to resist displacement; species employing this response, such as the aptly named Megabalanus, can reach 7 cm (3 in) in length;[3] other species may grow larger still (Austromegabalanus psittacus).
Competitors may include other barnacles, and disputed evidence indicates balanoid barnacles competitively displaced chthalamoid barnacles. Balanoids gained their advantage over the chthalamoids in the Oligocene, when they evolved tubular skeletons, which provide better anchorage to the substrate, and allow them to grow faster, undercutting, crushing, and smothering chthalamoids.[29]
Among the most common predators on barnacles are whelks. They are able to grind through the calcareous exoskeletons of barnacles and feed on the softer inside parts. Mussels also prey on barnacle larvae.[30] Another predator on barnacles is the starfish species Pisaster ochraceus.[31][32]
Barnacles and limpets compete for space in the intertidal zone
Barnacles and limpets compete for space in the intertidal zone
Goose barnacles, with their cirri extended for feeding
Goose barnacles, with their cirri extended for feeding
Underside of large Chesaconcavus sp. (Miocene) showing internal plates in bioimmured smaller barnacles
Underside of large Chesaconcavus sp. (Miocene) showing internal plates in bioimmured smaller barnacles
The anatomy of parasitic barnacles is generally simpler than that of their free-living relatives. They have no carapace or limbs, having only unsegmented sac-like bodies. Such barnacles feed by extending thread-like rhizomes of living cells into their hosts' bodies from their points of attachment.[9]
History of taxonomy
"Cirripedia" from Ernst Haeckel's Kunstformen der Natur (1904): The crab at the centre is nursing the externa of the parasitic cirripede Sacculina.
Barnacles were originally classified by Linnaeus and Cuvier as Mollusca, but in 1830 John Vaughan Thompson published observations showing the metamorphosis of the nauplius and cypris larvae into adult barnacles, and noted how these larvae were similar to those of crustaceans. In 1834 Hermann Burmeister published further information, reinterpreting these findings. The effect was to move barnacles from the phylum of Mollusca to Articulata, showing naturalists that detailed study was needed to reevaluate their taxonomy.[33]
Charles Darwin took up this challenge in 1846, and developed his initial interest into a major study published as a series of monographs in 1851 and 1854.[33] Darwin undertook this study, at the suggestion of his friend Joseph Dalton Hooker, to thoroughly understand at least one species before making the generalisations needed for his theory of evolution by natural selection.[34][35] Upon the conclusion of his research, Darwin declared "I hate a barnacle as no man ever did before."[36][35]
The name Cirripedia comes from the Latin words cirritus "curly" from cirrus "curl"[37] and pedis from pes "foot,"[38] the two words together mean "curl-footed."[39][further explanation needed] The study of barnacles is called cirripedology.
Classification
Some authorities regard the Cirripedia as a full class or subclass, and the orders listed above are sometimes treated as superorders. In 2001, Martin and Davis placed Cirripedia as an infraclass of Thecostraca and divided it into six orders:[40]
Infraclass Cirripedia Burmeister, 1834
Superorder Acrothoracica Gruvel, 1905
Order Pygophora Berndt, 1907
Order Apygophora Berndt, 1907
Superorder Rhizocephala Müller, 1862
Order Kentrogonida Delage, 1884
Order Akentrogonida Häfele, 1911
Superorder Thoracica Darwin, 1854
Order Pedunculata Lamarck, 1818
Order Sessilia Lamarck, 1818
In 2021, Chan et al. elevated Cirripedia to subclass of the class Thecostraca, and the superorders Acrothoracica, Rhizocephala, and Thoracica to infraclass. The updated classification, which now includes 11 orders, has been accepted in the World Register of Marine Species.[41][1]
Subclass Cirripedia Burmeister, 1834
Infraclass Acrothoracica Gruvel, 1905
Order Cryptophialida Kolbasov, Newman & Hoeg, 2009
Order Lithoglyptida Kolbasov, Newman & Hoeg, 2009
Infraclass Rhizocephala Müller, 1862
Infraclass Thoracica Darwin, 1854
Superorder Phosphatothoracica Gale, 2019
Order Iblomorpha Buckeridge & Newman, 2006
Order † Eolepadomorpha Chan et al., 2021
Superorder Thoracicalcarea Gale, 2015
Order Calanticomorpha Chan et al., 2021
Order Pollicipedomorpha Chan et al., 2021
Order Scalpellomorpha Buckeridge & Newman, 2006
Order † Archaeolepadomorpha Chan et al., 2021
Order † Brachylepadomorpha Withers, 1923
(Unranked) Sessilia
Order Balanomorpha Pilsbry, 1916
Order Verrucomorpha Pilsbry, 1916
Fossil record
The oldest definitive fossil barnacle is Praelepas from the mid-Carboniferous, around 330-320 million years ago.[42] Older claimed barnacles such as Priscansermarinus from the Middle Cambrian (on the order of 510 to 500 million years ago)[43] do not show clear barnacle morphological traits, though Rhamphoverritor from the Silurian Coalbrookdale Formation of England may represent a stem-group barnacle.[42] Barnacles first radiated and became diverse during the Late Cretaceous. Barnacles underwent a second, much larger radiation beginning during the Neogene (last 23 million years), which continues to present.[42] In part, their poor skeletal preservation is due to their restriction to high-energy environments, which tend to be erosional – therefore it is more common for their shells to be ground up by wave action than for them to reach a depositional setting.
Barnacles can play an important role in estimating paleo-water depths. The degree of disarticulation of fossils suggests the distance they have been transported, and since many species have narrow ranges of water depths, it can be assumed that the animals lived in shallow water and broke up as they were washed down-slope. The completeness of fossils, and nature of damage, can thus be used to constrain the tectonic history of regions.[3]
Balanus improvisus, one of the many barnacle taxa described by Charles Darwin
Balanus improvisus, one of the many barnacle taxa described by Charles Darwin
Miocene (Messinian) Megabalanus, smothered by sand and fossilised
Miocene (Messinian) Megabalanus, smothered by sand and fossilised
Chesaconcavus, a Miocene barnacle from Maryland
Chesaconcavus, a Miocene barnacle from Maryland
Relationship with humans
Barnacles are of economic consequence, as they often attach themselves to synthetic structures, sometimes to the structure's detriment. Particularly in the case of ships, they are classified as fouling organisms.[44] The number and size of barnacles that cover ships can impair their efficiency by causing hydrodynamic drag. This is not a problem for boats on inland waterways, as barnacles are exclusively marine. The stable isotope signals in the layers of barnacle shells can potentially be used as a forensic tracking method[45] for whales, loggerhead turtles[46] and marine debris, such as shipwrecks or a flaperon suspected to be from Malaysia Airlines Flight 370.[47][48][49]
The flesh of some barnacles is routinely consumed by humans, including Japanese goose barnacles (e.g. Capitulum mitella), and goose barnacles (e.g. Pollicipes pollicipes), a delicacy in Spain and Portugal.[50]
Additionally, the picoroco barnacle is used in Chilean cuisine and is one of the ingredients in curanto seafood stew.
MIT researchers developed an adhesive, inspired by a protein-based bioglue produced by barnacles to firmly attach to rocks, which can form a tight seal to halt bleeding within about 15 seconds of application.[51] Wikipedia
Eye gaze snapshots to assist in firmware image segmentation experiments of near real-time Left-Right forward scene projections. Eyelid elevation tracking. Azimuth pupil tracking.
Scanning IR back illumination Array - Not Shown
20. November 2019, Jugendstilhörsaal der MedUni Wien
“Multiparametic Diagnostics and Theranostics of Tumors”
Fabian Kiessling, Universitätsklinikum Aachen
Abstract:
Significant advances have been achieved in elucidating molecular regulations of cancer and numerous disease-related markers were identified. Additionally, imaging technologies steadily improved and are providing detailed insight into tissues’ morphology, function and molecular regulation. However, there is still a need to identify and quantify the most relevant information and to bring it into a mechanistic context.
In the first part of my talk, I present advanced imaging strategies to characterize tumors by assessing various “hallmarks of cancer” using non-invasive imaging and to assess therapy responses. In this context, I will discuss novel computer applications to improve data processing, lesion detection and segmentation as well as radiomic image analysis. However, taking a study on hepatocellular carcinoma therapy with a multispecific tyrosine kinase inhibitor as an example, I will also show that correlative analyses do not always lead to correct conclusions on biological mechanisms and that the interconnection and impact of the observed changes need to be understood.
The second part of my talk will be dedicated to drug delivery. Here, I will show how imaging can be used to improve the preselection of patients to therapies and discuss the value of nanomedicines and active targeting. Furthermore, I will highlight the potential of ultrasound mediated theranostics to overcome biological barriers and to improve tumor perfusion.
(c) MedUni Wien / Kovic
ref: www.fontplay.com/freephotos/4thfoldern/fp122905-22.jpg
Just a variant of Flamboyance. Added a segmentation step prior to running Brian's plugin. :)
There is congenital non-segmentation ("fusion") of the C2 and C3 vertebrae both in the centrum and the lateral masses. The sagittal appearance of the fused C2-C3 block mimics the dens and body of C2, leading to miscounting of the cervical vertebrae. The key is the invariable intimate relation of the anterior arch of the atlas to the true dens - which is seen to be a hypointense peg above the "pseudo-dens". The syrinx is at C7.
As technology segments rapidly evolved, so too did the need for ever evolving segmentation, including communications that provided customers to readily understand which products best suited their needs.
Image shows placement of a single front loaded primary transmit coil running across a 50MHz DDS (Direct-Digital-Synthesiser). The DDS includes full Freq-Phase modulation control for both power and data transfer. On-board circuitry also includes real time phase and magnitude monitoring of primary coil voltage and current waveforms allowing full monitoring of resulting transformer impedance and power coupling.
A single coil driver was included as a fallback option after requirements changes mandating direct wire galvanic coupling of signals into the eye via a percutaneous plug.
Advanced eye-tracking coil driver functions were subsequently removed from future designs with eye tracking then reverting to the use of mirrors and FPGA driven image segmentation ;-(
* Co-presenter
* How to deliver services to the Spanish speaking community
* Understanding minority communities
* Bilingual information
* Find the presentation at www.slideshare.net/joelnichols/total-branch-makeover
Cikuan Bra fishtail wedding, suffused with a soft sheen satin belt with good visual segmentation add layering, simple fishtail skirt lined sketched out the bride graceful posture, nestled in the tissue, akinds of the looming beauty, particularly sultry.
The orig photo was Segmentation using G'MIC(GIMP), then was painted using "Deep Paint 2" under WINE. Then was sent back to GIMP to clean-up. Deep Paint 2 is now a free program. Moalboal, Cebu, Philippines.
Theaters have recently started looping advertisements before their previews during films. This new advertising technique allows companies to segment their advertisements to specific audiences. According to Media Now, "technological changes and receptivity by audiences and advertisers encourage media to engage in narrowcasting, to target smaller, more specific audience segments with more specialized content" (39). If they are looking for a younger crowd to use their products then they might place their advertisements before the beginning of teen movies, for example.
This picture shows the evolution from the previous picture in Bangladesh.
- We clustered the participants we met according to their main occupation: small business owners, university students, high school students, artists, teachers and journalists.
- We then divided each group into 4 main zones: rejection, inability, ambivalence and embrace. You can see that the embrace zone changes size according to each group, to illustrate the groups that might be the most important to us. For example, we are more likely to find enthusiasm among artists than high school students, due to characteristics of their daily life.
- Within each zone, we listed the main patterns. For example, you can read that people who are unable to use our product are likely to be too poor or too illiterate.
- To move people from the ambivalence zone to the embrace zone, we highlighted motivators. For example, a University Student who is already satisfied by other tools will be very hesitant to use our product. However, if it is proven to be useful for specific task, they might embrace it.
Challenges: this graphic has proven to be too intense and detailed. We later refined it with a simpler segmentation and one page per cluster.
(Further pictures you can see quite easily by clicking on the link at the end of page!)
Vienna 1, The Franciscan Church
The Franciscans go back to St. Francis of Assisi and thus the 13th Century. They were founded as a mendicant orders but soon the arose the question how literally one should take the declaration of poverty. Was it allowed to make financial provision for elderly or sick brothers? Finally it came to the segmentation of the faith community, the more liberal Minoriten (Friars Minor Conventual) made their own order, while the Franciscans followed the old conventions. 1453 came the first Franciscan, John of Capistrano, to Vienna.
He founded the first Franciscan monastery in what is now 6th District. But the monks had to flee when the Turks besieged Vienna in 1529 and the monastery burned down. It took until 1589 until the city of Vienna gave them the at that time vacant monastery together with appendant church. The house, in its place now stands the monastery had already been donated in 1306 by wealthy citizens - namely for "loose women" who wanted give up their trade and convert themselves.
1476 was at the Weichenburg (hence Weihburggasse) inaugurated a church with seven altars, where formerly a "Pfarrheusl (small parsonage)" had stood for the soul welfare of the female residents. At the time of the Reformation, however, moral values in this house went downhill. 1553, the Foundation was dissolved, but it took yet until 1572 before the last resident had died. For eight years, the building was then an educational establishment for girls of poor people.
When the Franciscans now had got the property, they started in 1603 with a reconstruction of the church, which was consecrated in 1611. 1614, the foundation stone was laid for the new monastery.
The statues on the west facade are left Francis of Assisi and Anthony of Padua right. In the middle, on the pediment of the west portal of the Church stands Jerome, protector of the church. He is surrounded by two angle putti.
But let's go inside the church. Maria with the ax is the altarpiece above the high altar. The statue was carved in 1505 from lime wood and has its own story. She comes from the Green Mountain (Grünberg) in Bohemia, which was under the control the Sternberg family. Since the family in the meantime had become Protestant, it wanted to burn the statue. She were thrown into the fire - but the next day she stood unharmed again in the chapel. Now, the executioner was called who should dismember the effigy. However, even that was impossible, because the ax stuck in the shoulder of Mary and it was not possible to get it out. There it is still today. (You have to look closely, but then you see the great ax with slightly curved stem.) But that's not enough. A few years later the Madonna was lost in the gamble by a gegenreformierten (counter-reformed) Sternberg. The new owner, the Polish Baron Turnoffsky gave she in 1607 the Franciscan monastery. Exactly 100 years later, she got her current stand on the high altar.
The stone structure between altar and the statue of the Madonna also contains a crucifix, which dates from the beginning of the 17th Century. The wooden statues left and right represent the Saints Jerome respectively Francis and are typical examples of the so-called Franciscan carving school. It operated 1690-1730 and was run by lay brothers. The overall concept for the high altar dates back to the Jesuit Andrea dal Pozzo.
A special attraction is the organ by Hans Wöckherl that was already built in 1642 and today is the oldest organ in Vienna. It is, however, disappeared from the visible church, because it is behind the high altar and is only shown every Friday between 15.00 und 15.30 clock. In addition, one demans for that six euro entry...
The single-nave church has to both sides side chapels, of them I want to show two.
On the left we see the Magdalene Chapel, which was consecrated already in 1614 for the first time. 1644 and 1722, however, followed Neustiftungen (new foundings). The stucco decoration stems from 1644. The paintings in the vault are much more recent, from 1893. The altarpiece depicts the grieving Mary Magdalene under the Cross. It was created in 1725 by Carlo Innocenzo Carlone. The image above shows Veronica's handkerchief with the face of Christ. It was painted by Wolfram Koeberl and in 1974 installed. The statues beside the altar represent the Virgin Mary and John the Baptist. The two above chapels are provided with food grid, so that one could give Communion here.
An Immaculata chapel (pictured above right) is there since the existence of the church, but this was rebuilt in 1722. Previously, since 1642, there was a Michael altar here. From this period dates still the stucco decor on the ceiling. The altarpiece is by Johann Georg Schmidt, who painted it in 1721. The lateral statues depict the Saint Joachim and the mother of Mary.
Also the Capistrano Chapel, which was founded in 1723, is worth mentioning. The lateral stucco decor shows on the left side (picture) the glorification of St. John Capistrano, who, as I said, was the first Franciscan in Vienna. Right you can see him as a standard-bearer of Christian doctrine in the wars against the Turks. Both stucco images date from the time of the foundation. The altarpiece by Franz Xaver Wagenschön originated in 1761 and shows Capistrano in a scene from 1451, in Brescia when he healed a possessed man.
In the picture we see also the statue of Saint George, as he is killing the (admittedly small) dragon.
On the other side of the chapel is the Holy Florian, while Clara and Theresa stand next to the altar. Behind the altar there is a reliquary in glass from about 1720, in which we see a wax image of the Holy Hilaria. The relic shall be imbedded in the wax. Hilaria is rather unknown, but she was a martyr who was converted by Bishop Narcissus. She died in the year 304 in Augsburg, at the behest of the governor Gaius, because she did not want to renounce the Christian faith. About the nature of death, there are different opinions.
In the church there is a plaque that claims that she was burned at the grave of her daughter, while the Holy Encyclopedia states that she was enclosed in her house and this was then set on fire.
In the chapel opposite, the Chapel of the Good Shepherd, there is also a glass coffin with a relic. This is the skeleton of the Felix Puer wearing the uniform of a Roman Centurion.
As a counterpart to the pulpit, this just opposite, you will find the monument of Johann Nepomuk. We see how he flows on the water of the Vltava river after he was thrown in Prague there. He actually was called "John from Nepomuk" in Czech "ne Pomuk". The wife of Emperor Wenceslas IV is said to have chosen him as confessor. The Emperor wanted to know then what she had confessed, but Johann Nepomuk did not betray the seal of confession and was therefore thrown into the water. The Empress had then an appearance of five stars.
(We see she also in the water of the monument.) These stars indicated were one could find the body. So much for the legend.
The fact is that Johann Nepomuk was tortured by the king and thrown into the Vltava. The activating moment was a dispute over a new monastery between the emperor and the archbishop of Prague, in which John Nepomuk was trampled underfoot ...
The pulpit was built in 1726 and was executed by the Franciscan carving school. At the parapet there are wooden reliefs of Matthew, Mark and Luke. The relief of the fourth evangelist, John, is attached to the pulpit door. At the parapet you further can see statues of Capistrano and Bonaventura, while on the sounding board are sitting Anthony of Padua and Berhardin of Siena. At the top stands the freeze image of Francis of Assisi.
The pews were 1727 - 1729 by brother Johann Gottfried Hartmann built and carved.
WELSCH, Harold P. (Ed.). Entrepreneurship: the way ahead. Nova York: Routledge, 2004. xv, p. Inclui bibliografia e índice; il. tab. qua.; 25cm.
Notas de conteúdo:
1. Intellectual Foundations of Entrepreneurship
2. Unfinished Business (Entrepreneurship) of the 20th Century
3. Entrepreneurship Through the Ages
4. Science and Practice of New Business Ventures: Wealth Creation and Prosperity Through Entrepreneurship Growth and Renewal
5. Emerging Patterns of Entrepreneurship: Distinguishing Attributes of an Evolving Discipline
6. Opportunity Recognition
7. The Emergence of Entrepreneurial Marketing: Nature and Meaning
8. Bootstrap Finance
9. Entrepreneurial Growth: Predictors and Indicators
10. Entrepreneurial Failures: Key Challenges and Future Directions
11. Electronic Commerce: Current Understanding and Unanswered Questions
12. The Impact of Mobile Commerce on Small Business and Entrepreneurship
13. E-Commerce Entrepreneurship: Emerging Practices, Key Challenges and Future Directions
14. Developing Communities, People and Businesses: In Search of a Model of Community-based Enterprises
15. Wealth Creation in Distressed Inner Cities: What Can Business Schools Contribute?
16. Women Entrepreneurs in the New Mellinnium: Recent Progress and Future Directions for Research, Entrepreneurship Development and Teaching
17. Serial Entrepreneurship: An In-Depth Look at the Phenomenon of Habitual Entrepreneurs
18. Immigrant and Ethnic Entrepreneurship: A U.S. Perspective
19. Innovations in Entrepreneurship Education: Strategy and Tactics for Joining the Ranks of Innovative Entrepreneurship Programs in Higher Education
20. Entrepreneurship Education: Market Segmentation and Lerner Needs
Palavras-chave:
EMPREENDEDORISMO; COMERCIO ELETRONICO; NOVAS EMPRESAS COMERCIAIS.
CDU 658 / W458e / 2004
My mum and dad gave me this beautiful old sewing box for my 30th birthday last year. I'm on a mission to make better use of it and started by reorganising all my embroidery thread.
Appboy briefs investors on Appboy Mobile Marketing Automation Platform in the Marketing session during DEMO Traction, the Growth Conference, at the Mission Bay Conference Center in San Francisco, California, Wednesday, April 22, 2015. The Appboy platform empowers marketers to increase mobile engagement through intelligent, data-driven campaigns. Its suite of services empower brands to solve app abandonment and manage the customer life cycle. By employing robust user profiles, rich customer segmentation, and multi-channel messaging, brands can effectively cultivate relationships with their customer base. More information on Appboy can be found at bit.ly/DEMO-Appboy. DEMO Traction is focused obsessively on growth by connecting the most promising growth startups with prospective customers, investors and strategic partners. DEMO Traction is an invite-only event for startups solving problems using cutting-edge technology who are exhibiting traction or are on the cusp of a major growth spurt. Photo by Stephen Brashear (www.stephenbrashear.com)
For complete coverage of DEMO Traction visit bit.ly/DEMOsite.
(www.adgorithms.com) - The internet, since it started in mid-1990 has definitely turned out to be a great source of performance advertising. This kind of media has pulled towards advertisers as a more dynamic way to get closer to their consumers.
20. November 2019, Jugendstilhörsaal der MedUni Wien
“Multiparametic Diagnostics and Theranostics of Tumors”
Fabian Kiessling, Universitätsklinikum Aachen
Abstract:
Significant advances have been achieved in elucidating molecular regulations of cancer and numerous disease-related markers were identified. Additionally, imaging technologies steadily improved and are providing detailed insight into tissues’ morphology, function and molecular regulation. However, there is still a need to identify and quantify the most relevant information and to bring it into a mechanistic context.
In the first part of my talk, I present advanced imaging strategies to characterize tumors by assessing various “hallmarks of cancer” using non-invasive imaging and to assess therapy responses. In this context, I will discuss novel computer applications to improve data processing, lesion detection and segmentation as well as radiomic image analysis. However, taking a study on hepatocellular carcinoma therapy with a multispecific tyrosine kinase inhibitor as an example, I will also show that correlative analyses do not always lead to correct conclusions on biological mechanisms and that the interconnection and impact of the observed changes need to be understood.
The second part of my talk will be dedicated to drug delivery. Here, I will show how imaging can be used to improve the preselection of patients to therapies and discuss the value of nanomedicines and active targeting. Furthermore, I will highlight the potential of ultrasound mediated theranostics to overcome biological barriers and to improve tumor perfusion.
(c) MedUni Wien / Kovic
(www.adgorithms.com) - You can always come up with catchy and attractive performance advertising. The possibilities are endless; you can maybe create your video advertising.
feeding on desert foliage
Valley of Fire state park, NV Clark Co
May, 2007
possibly Hemileuca hera - buck moth??
Majin Buu was one of the final villains introduced in the Dragonball Z series, and main reason for everyone powering up again. His most famous form in this arc is that of Innocent Buu, which is the pink blob.. which also appears to be his look when he's split up into Good Buu and Kid Buu.... anyway.
Despite his childlike appearance and behavior, he's one of the most horrific beings to ever exist (at that time, of course... everyone is always the worst thing ever when they're introduced), only held back as it were by some influence of a Grand Kai that was absorbed earlier in his existence. He's basically Kirby if he went rogue.
The character is of course represented in Figuarts form.
As the Dragonball releases general scale to each other, Buu is gigantic, not quite reaching Broly size, but pretty close, and dwarfs all of the other Z fighters. Being an extremely large figure, Buu is definitely more hollow as compared to his smaller peers, most notably in the body itself. Some of this is for the better, as that is where the guts of this articulation is hidden.
It's just unfortunate the younger generation will never know the joys of beating the shit out of your friends with 10 inch rubber WWF figures.
Buu comes with 3 heads, with I believe a bonus "Good Buu" head with the upcoming Kid Buu Figuarts. No stand and relatively few hands, but he does come with his trademark chocolate bar, which apparently if he's Innocent Buu is probably someone transformed into food, or if he's Good Buu it's literally a chocolate bar as he can't absorb people anymore.
All I know is he eats no matter where he goes.
In addition to the aforementioned, you will also notice he has his trademark purple cape, slightly poseable due to the segmentation. It's not as poseable as say, the Batman ones from Play Arts, but it also doesn't look anywhere as hideous so... winning?
Colours are nice and sharp, much like on Gotenks. I don't know how things are like on other Figuarts lines, but it does seem like Bandai has gotten their act together at least on the Dragonball stuff. Of course, given its premium status, it's kind of necessary.
Articulation is pretty good too. It's not quite Storm Collectibles Zangief good, but it's on part with Broly, meaning the only real thing missing is an upper chest joint. As mentioned, hollow cavities allow for joint placements that increase his range of movement. Of course, due to his size, the actual poses Buu can hold without additional support are kind of limited though I don't exactly recall him being a super limber kind of guy. A standard figure stand won't support him, so if you want to do any mid air posing, you're going to need to find something more robust, or get creative.
While they're all memorable characters, you got to admit in a line where more than half of them seem to basically be a bipedal humanoid with two arms that share the same workout routine, it's the aliens and other seemingly random characters that stick out on your shelves. Majin Buu is no exception - I think he makes a great accent piece in your Figuarts sized collection, regardless if its Dragonball or not.
Much like with Broly, Buu is large and in charge and is a great addition to your set, but I wouldn't go in expecting him to be a posing dynamo, which is usually the case with larger figures (except for Storm Zangief), though really I feel the only point missing would be an articulation point at the chest.
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(www.adgorithms.com) - The size and the content of the performance advertising change in the webpage.
Hum, disregard that. It's something on my machine and happens at other occasions. I'm yet to find out if it's related to Flash or Java.
Screenshot taken moments before Mozilla crash.
Quoted from the official geotag bug thread at Flickr forums:
Mozilla segmentation fault
Both Mozilla Suite and Firefox crash and print Segmentation fault at stdout when finishing loading a Flickr map. OS is Debian Linux.
The test page was taken from the Flickr blog.
Screenshot taken moments before the crash: www.flickr.com/photos/vieira/239943709/
The browsers "signatures":
Mozilla/5.0 (X11; U; Linux i686; pt-BR; rv:1.7.10) Gecko/20060804 Firefox/1.0.4 (Debian package 1.0.4-2sarge10)
Mozilla/5.0 (X11; U; Linux i686; rv:1.7.8) Gecko/20060803 Debian/1.7.8-1sarge7.2.1
I love this! The chess pieces in top row are exactly the same shade of grey as those in the bottom row. Only the background is changed.
Originally taken from this research paper:
Image segmentation and lightness perception. Anderson BL, Winawer J. Nature. 2005 Mar 3;434(7029):79-83.
Re-found when 'tidying' my laptop desktop.
Majin Buu was one of the final villains introduced in the Dragonball Z series, and main reason for everyone powering up again. His most famous form in this arc is that of Innocent Buu, which is the pink blob.. which also appears to be his look when he's split up into Good Buu and Kid Buu.... anyway.
Despite his childlike appearance and behavior, he's one of the most horrific beings to ever exist (at that time, of course... everyone is always the worst thing ever when they're introduced), only held back as it were by some influence of a Grand Kai that was absorbed earlier in his existence. He's basically Kirby if he went rogue.
The character is of course represented in Figuarts form.
As the Dragonball releases general scale to each other, Buu is gigantic, not quite reaching Broly size, but pretty close, and dwarfs all of the other Z fighters. Being an extremely large figure, Buu is definitely more hollow as compared to his smaller peers, most notably in the body itself. Some of this is for the better, as that is where the guts of this articulation is hidden.
It's just unfortunate the younger generation will never know the joys of beating the shit out of your friends with 10 inch rubber WWF figures.
Buu comes with 3 heads, with I believe a bonus "Good Buu" head with the upcoming Kid Buu Figuarts. No stand and relatively few hands, but he does come with his trademark chocolate bar, which apparently if he's Innocent Buu is probably someone transformed into food, or if he's Good Buu it's literally a chocolate bar as he can't absorb people anymore.
All I know is he eats no matter where he goes.
In addition to the aforementioned, you will also notice he has his trademark purple cape, slightly poseable due to the segmentation. It's not as poseable as say, the Batman ones from Play Arts, but it also doesn't look anywhere as hideous so... winning?
Colours are nice and sharp, much like on Gotenks. I don't know how things are like on other Figuarts lines, but it does seem like Bandai has gotten their act together at least on the Dragonball stuff. Of course, given its premium status, it's kind of necessary.
Articulation is pretty good too. It's not quite Storm Collectibles Zangief good, but it's on part with Broly, meaning the only real thing missing is an upper chest joint. As mentioned, hollow cavities allow for joint placements that increase his range of movement. Of course, due to his size, the actual poses Buu can hold without additional support are kind of limited though I don't exactly recall him being a super limber kind of guy. A standard figure stand won't support him, so if you want to do any mid air posing, you're going to need to find something more robust, or get creative.
While they're all memorable characters, you got to admit in a line where more than half of them seem to basically be a bipedal humanoid with two arms that share the same workout routine, it's the aliens and other seemingly random characters that stick out on your shelves. Majin Buu is no exception - I think he makes a great accent piece in your Figuarts sized collection, regardless if its Dragonball or not.
Much like with Broly, Buu is large and in charge and is a great addition to your set, but I wouldn't go in expecting him to be a posing dynamo, which is usually the case with larger figures (except for Storm Zangief), though really I feel the only point missing would be an articulation point at the chest.
Prague City Gallery – Municipal Library (Městská knihovna)
The library building on Mariánské Square was built between 1925 and 1928. It was the first purpose-built library in the then Czechoslovakia as well as one of the most modern in Europe at the time. The exhibition space on the second floor is used by the Prague City Gallery. Its mission is focused primarily on presenting Czech modern art from the 19th and 20th centuries.
The oldest public library in Prague continued in the activity of the society libraries, and also some marginal villages had their own libraries. The first public library in Prague was opened on the 1st July 1891, being established by a decree of the municipal council as the Public Municipal Library of the Royal City of Prague. In the beginning, it had over 3000 books; its first address was in the building of the former St. Václav jail in the Na Zderaze Street. The library changed its address several times, until it finally settled at the corner of Platnéřská Street and the square Mariánské náměstí, where there used to be an Empire burgess house. The base of the modern-time library was set by its director back then, poet Antonín Sova, who also established the first six branches of the library. When 37 surrounding villages were included in Prague in 1922, which also gave rise to the so called Great Prague, also the libraries in these villages were united into one and a centralized Central Library of the Capital City of Prague was created with a network of 40 branches and this number kept growing. The library fund with approximately 260 thousand volumes was also increasing rapidly. The existing house was not suitable for the greater amounts of books. This problem was resolved by the Prague Municipal Insurance Company, which as early as in 1923 decided in a meeting of its board of directors to build a new separate building for the library needs and to donate it to the city of Prague on the occasion of the 10th anniversary of the Czechoslovak State. Out of five renowned architects, František Roith was the one to win the competition opened for the new library project. Work on the extensive building site, which was over 60 m long into the Mariánské náměstí and nearly 70 m in the vertical direction, began in 1925. This was the first purpose-built library construction in Czechoslovakia and one of the most modern in Europe. The author not only designed the new building as a magnificent library with all the respective services, but also as a cultural institution with premises for lectures, concerts and exhibitions. The library was officially opened for public on the 28th October 1928.
A markedly traditionally designed building looks very suitable between the early-Baroque Clementinum and the Secession building of the New Prague Town Hall. The main front of the object unites modern temperance with Classicising segmentation. The corner parts with arcades extend into the pavement, and there is a monumental port with a balcony balustrade in the middle. On the balcony, there are 6 allegorical sculptures made by Ladislav Kofránek. The main facade, as well as the side tract, are lined by Slovak travertine. Also the interior is simple and strictly purposeful, even if a little more decorative. The monumental staircase and vestibule again use travertine, artificial stone and brass. Ornamental paintings on the ceiling of the central hall were realized by František Kysela. Even the furniture and equipment corresponded with the building’s simple and purposeful architecture. Today, the original equipment can only be seen the information centre and the theatre section.
Premises for puppet theatre were built in the underground, on the side in Žatecká Street. The theatre came here from Bubeneč. A model of the scene and auditorium was realized by sculptor and woodcarver Vojtěch Sucharda, who was the founder and the first director of the local Artistic Scene of the Puppet Land (Říše loutek).
About one fifth of the building is taken up by the residence of Prague’s chief magistrate on the first and on the second floor of the front tract, which is made up of the service flat, representative and reception lounges, an apartment for accommodating precious guests, and operational background. The residence has its own access from the corner of Platnéřská and Žatecká Street. The residence utterly leaves the idea of an overall restrained purposefulness. It is decorative, noble and cultured Art Deco style. František Kysela participated in the decorations and he realized the ceiling paintings and designed a large tapestry named Work, Science and Arts. Equipment and decorations of the chief magistrate’s residence were completed in 1930. However, the Prague chief magistrates never actually lived in the residence, perhaps with the only exception of Karel Baxa. It was, nevertheless, regularly used for accommodating official foreign visitors and for protocolar and representative purposes. In the years 1994 - 95 it went through a general reconstruction and the pieces of art were carefully restored.
Modernity and generosity of the Roith’s project of a library from the era of the first republic is documented by the fact that only in the end of the 1970s, the library no longer suited the needs of a modern information institute, both spatially and technologically. The city initiated a generous building reconstruction in the years 1996 - 98. All the lending and studying areas were connected during the reconstruction, and free selection of the library fund was increased. The surface area extended by 900 m2 thanks to placing ceilings on two atriums and to in-built galleries.
www.prague.eu/en/object/places/860/prague-city-gallery-mu...
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