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Ipê Amarelo, Tabebuia [chrysotricha or ochracea].
Ipê-amarelo em Brasília (UnB), Brasil.
This tree is in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Ipê Amarelo, Tabebuia [chrysotricha or ochracea].
Ipê-amarelo em Brasília, Brasil.
This tree is in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Naturgetreue Abblidungen und Beschreibungen der essbaren, schädlichen und verdächtigen Schwämme /
Prag :In Commission in der J. G. Calve'schen Buchhandlung,1831-1846.
Maize (/meɪz/ MAYZ; Zea mays subsp. mays, from Spanish: maíz after Taino: mahiz), also known as corn (North American and Australian English), is a cereal grain first domesticated by indigenous peoples in southern Mexico about 10,000 years ago. The leafy stalk of the plant produces pollen inflorescences and separate ovuliferous inflorescences called ears that yield kernels or seeds, which are fruits.
Maize has become a staple food in many parts of the world, with the total production of maize surpassing that of wheat or rice. In addition to being consumed directly by humans (often in the form of masa), maize is also used for corn ethanol, animal feed and other maize products, such as corn starch and corn syrup. The six major types of maize are dent corn, flint corn, pod corn, popcorn, flour corn, and sweet corn. Sugar-rich varieties called sweet corn are usually grown for human consumption as kernels, while field corn varieties are used for animal feed, various corn-based human food uses (including grinding into cornmeal or masa, pressing into corn oil, and fermentation and distillation into alcoholic beverages like bourbon whiskey), and as chemical feedstocks. Maize is also used in making ethanol and other biofuels.
Maize is widely cultivated throughout the world, and a greater weight of maize is produced each year than any other grain. In 2014, total world production was 1.04 billion tonnes. Maize is the most widely grown grain crop throughout the Americas, with 361 million metric tons grown in the United States alone in 2014. Genetically modified maize made up 85% of the maize planted in the United States in 2009. Subsidies in the United States help to account for its high level of cultivation of maize and its position as the largest producer in the world.
HISTORY
PRE-COLUMBIAN DEVELOPMENT
Maize is a cultigen; human intervention is required for it to propagate. Whether or not the kernels fall off the cob on their own is a key piece of evidence used in archaeology to distinguish domesticated maize from its naturally-propagating teosinte ancestor. Genetic evidence can also be used to determine when various lineages split.
Most historians believe maize was domesticated in the Tehuacán Valley of Mexico. Recent research in the early 21st century has modified this view somewhat; scholars now indicate the adjacent Balsas River Valley of south-central Mexico as the center of domestication.
An influential 2002 study by Matsuoka et al. has demonstrated that, rather than the multiple independent domestications model, all maize arose from a single domestication in southern Mexico about 9,000 years ago. The study also demonstrated that the oldest surviving maize types are those of the Mexican highlands. Later, maize spread from this region over the Americas along two major paths. This is consistent with a model based on the archaeological record suggesting that maize diversified in the highlands of Mexico before spreading to the lowlands.
Archaeologist Dolores Piperno has said:
A large corpus of data indicates that [maize] was dispersed into lower Central America by 7600 BP [5600 BC] and had moved into the inter-Andean valleys of Colombia between 7000 and 6000 BP [5000–4000 BC].
— Dolores Piperno, The Origins of Plant Cultivation and Domestication in the New World Tropics: Patterns, Process, and New Developments
Since then, even earlier dates have been published.
According to a genetic study by Embrapa, corn cultivation was introduced in South America from Mexico, in two great waves: the first, more than 6000 years ago, spread through the Andes. Evidence of cultivation in Peru has been found dating to about 6700 years ago. The second wave, about 2000 years ago, through the lowlands of South America.
The earliest maize plants grew only small, 25-millimetre-long (1 in) corn cobs, and only one per plant. In Jackson Spielvogel's view, many centuries of artificial selection (rather than the current view that maize was exploited by interplanting with teosinte) by the indigenous people of the Americas resulted in the development of maize plants capable of growing several cobs per plant, which were usually several centimetres/inches long each. The Olmec and Maya cultivated maize in numerous varieties throughout Mesoamerica; they cooked, ground and processed it through nixtamalization. It was believed that beginning about 2500 BC, the crop spread through much of the Americas. Research of the 21st century has established even earlier dates. The region developed a trade network based on surplus and varieties of maize crops.
Mapuches of south-central Chile cultivated maize along with quinoa and potatoes in pre-Hispanic times; however, potato was the staple food of most Mapuches, "specially in the southern and coastal [Mapuche] territories where maize did not reach maturity". Before the expansion of the Inca Empire maize was traded and transported as far south as 40°19' S in Melinquina, Lácar Department. In that location maize remains were found inside pottery dated to 730 ± 80 BP and 920 ± 60 BP. Probably this maize was brought across the Andes from Chile. The presence of maize in Guaitecas Archipelago (43°55' S), the southernmost outpost of pre-Hispanic agriculture, is reported by early Spanish explorers. However the Spanish may have misidentified the plant.
COLUMBIAN EXCHANGE
After the arrival of Europeans in 1492, Spanish settlers consumed maize, and explorers and traders carried it back to Europe and introduced it to other countries. Spanish settlers far preferred wheat bread to maize, cassava, or potatoes. Maize flour could not be substituted for wheat for communion bread, since in Christian belief only wheat could undergo transubstantiation and be transformed into the body of Christ. Some Spaniards worried that by eating indigenous foods, which they did not consider nutritious, they would weaken and risk turning into Indians. "In the view of Europeans, it was the food they ate, even more than the environment in which they lived, that gave Amerindians and Spaniards both their distinctive physical characteristics and their characteristic personalities." Despite these worries, Spaniards did consume maize. Archeological evidence from Florida sites indicate they cultivated it as well.
Maize spread to the rest of the world because of its ability to grow in diverse climates. It was cultivated in Spain just a few decades after Columbus's voyages and then spread to Italy, West Africa and elsewhere. Widespread cultivation most likely began in southern Spain in 1525, after which it quickly spread to the rest of the Spanish Empire including its territories in Italy (and, from there, to other Italian states). Maize had many advantages over wheat and barley; it yielded two and a half times the food energy per unit cultivated area, could be harvested in successive years from the same plot of land, and grew in wildly varying altitudes and climates, from relatively dry regions with only 250 mm (10 in) of annual rainfall to damp regions with over 5,000 mm (200 in). By the 17th century it was a common peasant food in Southwestern Europe, including Portugal, Spain, southern France, and Italy. By the 18th century, it was the chief food of the southern French and Italian peasantry, especially in the form of polenta in Italy.
Names
The word maize derives from the Spanish form of the indigenous Taíno word for the plant, mahiz. It is known by other names around the world.
The word "corn" outside the US, Canada, Australia, and New Zealand refers to any cereal crop, its meaning understood to vary geographically to refer to the local staple. In the United States, Canada, Australia, and New Zealand, corn primarily means maize; this usage started as a shortening of "Indian corn". "Indian corn" primarily means maize (the staple grain of indigenous Americans), but can refer more specifically to multicolored "flint corn" used for decoration.
In places outside the US, Canada, Australia, and New Zealand, corn often refers to maize in culinary contexts. The narrower meaning is usually indicated by some additional word, as in sweet corn, sweetcorn, corn on the cob, baby corn, the puffed confection known as popcorn and the breakfast cereal known as corn flakes.
In Southern Africa, maize is commonly called mielie (Afrikaans) or mealie (English), words derived from the Portuguese word for maize, milho.
Maize is preferred in formal, scientific, and international usage because it refers specifically to this one grain, unlike corn, which has a complex variety of meanings that vary by context and geographic region. Maize is used by agricultural bodies and research institutes such as the FAO and CSIRO. National agricultural and industry associations often include the word maize in their name even in English-speaking countries where the local, informal word is something other than maize; for example, the Maize Association of Australia, the Indian Maize Development Association, the Kenya Maize Consortium and Maize Breeders Network, the National Maize Association of Nigeria, the Zimbabwe Seed Maize Association.
STRUCTURE AND PHYSIOLOGY
The maize plant is often 3 m (10 ft) in height, though some natural strains can grow 13 m (43 ft). The stem is commonly composed of 20 internodes of 18 cm (7 in) length. The leaves arise from the nodes, alternately on opposite sides on the stalk. A leaf, which grows from each node, is generally 9 cm (3+1⁄2 in) in width and 120 cm (3 ft 11 in) in length.
Ears develop above a few of the leaves in the midsection of the plant, between the stem and leaf sheath, elongating by around 3 mm (1⁄8 in) per day, to a length of 18 cm (7 in) with 60 cm (24 in) being the maximum alleged in the subspecies. They are female inflorescences, tightly enveloped by several layers of ear leaves commonly called husks. Certain varieties of maize have been bred to produce many additional developed ears. These are the source of the "baby corn" used as a vegetable in Asian cuisine.
The apex of the stem ends in the tassel, an inflorescence of male flowers. When the tassel is mature and conditions are suitably warm and dry, anthers on the tassel dehisce and release pollen. Maize pollen is anemophilous (dispersed by wind), and because of its large settling velocity, most pollen falls within a few meters of the tassel.
Elongated stigmas, called silks, emerge from the whorl of husk leaves at the end of the ear. They are often pale yellow and 18 cm (7 in) in length, like tufts of hair in appearance. At the end of each is a carpel, which may develop into a "kernel" if fertilized by a pollen grain. The pericarp of the fruit is fused with the seed coat referred to as "caryopsis", typical of the grasses, and the entire kernel is often referred to as the "seed". The cob is close to a multiple fruit in structure, except that the individual fruits (the kernels) never fuse into a single mass. The grains are about the size of peas, and adhere in regular rows around a white, pithy substance, which forms the ear. The maximum size of kernels is reputedly 2.5 cm (1 in). An ear commonly holds 600 kernels. They are of various colors: blackish, bluish-gray, purple, green, red, white and yellow. When ground into flour, maize yields more flour with much less bran than wheat does. It lacks the protein gluten of wheat and, therefore, makes baked goods with poor rising capability. A genetic variant that accumulates more sugar and less starch in the ear is consumed as a vegetable and is called sweet corn. Young ears can be consumed raw, with the cob and silk, but as the plant matures (usually during the summer months), the cob becomes tougher and the silk dries to inedibility. By the end of the growing season, the kernels dry out and become difficult to chew without cooking them tender first in boiling water.
Planting density affects multiple aspects of maize. Modern farming techniques in developed countries usually rely on dense planting, which produces one ear per stalk. Stands of silage maize are yet denser,[citation needed] and achieve a lower percentage of ears and more plant matter.
Maize is a facultative short-day plant and flowers in a certain number of growing degree days > 10 °C (50 °F) in the environment to which it is adapted. The magnitude of the influence that long nights have on the number of days that must pass before maize flowers is genetically prescribed and regulated by the phytochrome system.
Photoperiodicity can be eccentric in tropical cultivars such that the long days characteristic of higher latitudes allow the plants to grow so tall that they do not have enough time to produce seed before being killed by frost. These attributes, however, may prove useful in using tropical maize for biofuels.
Immature maize shoots accumulate a powerful antibiotic substance, 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA). DIMBOA is a member of a group of hydroxamic acids (also known as benzoxazinoids) that serve as a natural defense against a wide range of pests, including insects, pathogenic fungi and bacteria. DIMBOA is also found in related grasses, particularly wheat. A maize mutant (bx) lacking DIMBOA is highly susceptible to attack by aphids and fungi. DIMBOA is also responsible for the relative resistance of immature maize to the European corn borer (family Crambidae). As maize matures, DIMBOA levels and resistance to the corn borer decline.
Because of its shallow roots, maize is susceptible to droughts, intolerant of nutrient-deficient soils, and prone to be uprooted by severe winds.
While yellow maizes derive their color from lutein and zeaxanthin, in red-colored maizes, the kernel coloration is due to anthocyanins and phlobaphenes. These latter substances are synthesized in the flavonoids synthetic pathway from polymerization of flavan-4-ols by the expression of maize pericarp color1 (p1) gene which encodes an R2R3 myb-like transcriptional activator of the A1 gene encoding for the dihydroflavonol 4-reductase (reducing dihydroflavonols into flavan-4-ols) while another gene (Suppressor of Pericarp Pigmentation 1 or SPP1) acts as a suppressor. The p1 gene encodes an Myb-homologous transcriptional activator of genes required for biosynthesis of red phlobaphene pigments, while the P1-wr allele specifies colorless kernel pericarp and red cobs, and unstable factor for orange1 (Ufo1) modifies P1-wr expression to confer pigmentation in kernel pericarp, as well as vegetative tissues, which normally do not accumulate significant amounts of phlobaphene pigments. The maize P gene encodes a Myb homolog that recognizes the sequence CCT/AACC, in sharp contrast with the C/TAACGG bound by vertebrate Myb proteins.
The ear leaf is the leaf most closely associated with a particular developing ear. This leaf and above contribute 70% to 75% to 90% of grain fill. Therefore fungicide application is most important in that region in most disease environments.
ABNORMAL FLOWERS
Maize flowers may sometimes exhibit mutations that lead to the formation of female flowers in the tassel. These mutations, ts4 and Ts6, prohibit the development of the stamen while simultaneously promoting pistil development. This may cause inflorescences containing both male and female flowers, or hermaphrodite flowers.
GENETICS
Maize is an annual grass in the family Gramineae, which includes such plants as wheat, rye, barley, rice, sorghum, and sugarcane. There are two major species of the genus Zea (out of six total): Zea mays (maize) and Zea diploperennis, which is a perennial type of teosinte. The annual teosinte variety called Zea mays mexicana is the closest botanical relative to maize. It still grows in the wild as an annual in Mexico and Guatemala.
Many forms of maize are used for food, sometimes classified as various subspecies related to the amount of starch each has:
Flour corn: Zea mays var. amylacea
Popcorn: Zea mays var. everta
Dent corn : Zea mays var. indentata
Flint corn: Zea mays var. indurata
Sweet corn: Zea mays var. saccharata and Zea mays var. rugosa
Waxy corn: Zea mays var. ceratina
Amylomaize: Zea mays
Pod corn: Zea mays var. tunicata Larrañaga ex A. St. Hil.
Striped maize: Zea mays var. japonica
This system has been replaced (though not entirely displaced) over the last 60 years by multivariable classifications based on ever more data. Agronomic data were supplemented by botanical traits for a robust initial classification, then genetic, cytological, protein and DNA evidence was added. Now, the categories are forms (little used), races, racial complexes, and recently branches.
Maize is a diploid with 20 chromosomes (n=10). The combined length of the chromosomes is 1500 cM. Some of the maize chromosomes have what are known as "chromosomal knobs": highly repetitive heterochromatic domains that stain darkly. Individual knobs are polymorphic among strains of both maize and teosinte.
Barbara McClintock used these knob markers to validate her transposon theory of "jumping genes", for which she won the 1983 Nobel Prize in Physiology or Medicine. Maize is still an important model organism for genetics and developmental biology today.
The centromeres have two types of structural components, both of which are found only in the centromeres: Large arrays of CentC, a short satellite DNA; and a few of a family of retrotransposons. The B chromosome, unlike the others, contains an additional repeat which extends into neighboring areas of the chromosome. Centromeres can accidentally shrink during division and still function, although it is thought this will fail if it shrinks below a few hundred kilobase. Kinetochores contain RNA originating from centromeres. Centromere regions can become inactive, and can continue in that state if the chromosome still has another active one.
The Maize Genetics Cooperation Stock Center, funded by the USDA Agricultural Research Service and located in the Department of Crop Sciences at the University of Illinois at Urbana-Champaign, is a stock center of maize mutants. The total collection has nearly 80,000 samples. The bulk of the collection consists of several hundred named genes, plus additional gene combinations and other heritable variants. There are about 1000 chromosomal aberrations (e.g., translocations and inversions) and stocks with abnormal chromosome numbers (e.g., tetraploids). Genetic data describing the maize mutant stocks as well as myriad other data about maize genetics can be accessed at MaizeGDB, the Maize Genetics and Genomics Database.
In 2005, the US National Science Foundation (NSF), Department of Agriculture (USDA) and the Department of Energy (DOE) formed a consortium to sequence the B73 maize genome. The resulting DNA sequence data was deposited immediately into GenBank, a public repository for genome-sequence data. Sequences and genome annotations have also been made available throughout the project's lifetime at the project's official site.
Primary sequencing of the maize genome was completed in 2008. On November 20, 2009, the consortium published results of its sequencing effort in Science. The genome, 85% of which is composed of transposons, was found to contain 32,540 genes (By comparison, the human genome contains about 2.9 billion bases and 26,000 genes). Much of the maize genome has been duplicated and reshuffled by helitrons—group of rolling circle transposons.
In Z. mays and various other angiosperms the MADS-box motif is involved in floral development. Early study in several angiosperm models including Z. mays was the beginning of research into the molecular evolution of floral structure in general, as well as their role in nonflowering plants.
EVOLUTION
As with many plants and animals, Z. mays has a positive correlation between effective population size and the magnitude of selection pressure. Z. m. having an EPS of ~650,000, it clusters with others of about the same EPS, and has 79% of its amino acid sites under selection.
Recombination is a significant source of diversity in Z. mays. (Note that this finding supersedes previous studies which showed no such correlation.)
This recombination/diversity effect is seen throughout plants but is also found to not occur – or not as strongly – in regions of high gene density. This is likely the reason that domesticated Z. mays has not seen as much of an increase in diversity within areas of higher density as in regions of lower density, although there is more evidence in other plants.
Some lines of maize have undergone ancient polyploidy events, starting 11m years ago. Over that time ~72% of polyploid duplicated genes have been retained, which is higher than other plants with older polyploidy events. Thus maize may be due to lose more duplicate genes as time goes along, similar to the course followed by the genomes of other plants. If so - if gene loss has merely not occurred yet - that could explain the lack of observed positive selection and lower negative selection which are observed in otherwise similar plants, i.e. also naturally outcrossing and with similar effective population sizes.
Ploidy does not appear to influence EPS or magnitude of selection effect in maize.
BREEDING
Maize reproduces sexually each year. This randomly selects half the genes from a given plant to propagate to the next generation, meaning that desirable traits found in the crop (like high yield or good nutrition) can be lost in subsequent generations unless certain techniques are used.
Maize breeding in prehistory resulted in large plants producing large ears. Modern breeding began with individuals who selected highly productive varieties in their fields and then sold seed to other farmers. James L. Reid was one of the earliest and most successful developing Reid's Yellow Dent in the 1860s. These early efforts were based on mass selection. Later breeding efforts included ear to row selection (C. G. Hopkins c. 1896), hybrids made from selected inbred lines (G. H. Shull, 1909), and the highly successful double cross hybrids using four inbred lines (D. F. Jones c. 1918, 1922). University supported breeding programs were especially important in developing and introducing modern hybrids. By the 1930s, companies such as Pioneer devoted to production of hybrid maize had begun to influence long-term development. Internationally important seed banks such as the International Maize and Wheat Improvement Center (CIMMYT) and the US bank at the Maize Genetics Cooperation Stock Center University of Illinois at Urbana-Champaign maintain germplasm important for future crop development.
Since the 1940s the best strains of maize have been first-generation hybrids made from inbred strains that have been optimized for specific traits, such as yield, nutrition, drought, pest and disease tolerance. Both conventional cross-breeding and genetic modification have succeeded in increasing output and reducing the need for cropland, pesticides, water and fertilizer. There is conflicting evidence to support the hypothesis that maize yield potential has increased over the past few decades. This suggests that changes in yield potential are associated with leaf angle, lodging resistance, tolerance of high plant density, disease/pest tolerance, and other agronomic traits rather than increase of yield potential per individual plant.
Tropical landraces remain an important and underutilized source of resistance alleles for for disease and for herbivores. Notable discoveries of rare alleles for this purpose were made by Dao et al 2014 and Sood et al 2014.
GLOBAL PROGRAM
CIMMYT operates a conventional breeding program to provide optimized strains. The program began in the 1980s. Hybrid seeds are distributed in Africa by the Drought Tolerant Maize for Africa project.
GENETIC MODIFICATION
Genetically modified (GM) maize was one of the 26 GM crops grown commercially in 2016. The vast majority of this is Bt maize. Grown since 1997 in the United States and Canada, 92% of the US maize crop was genetically modified in 2016 and 33% of the worldwide maize crop was GM in 2016. As of 2011, Herbicide-tolerant maize varieties were grown in Argentina, Australia, Brazil, Canada, China, Colombia, El Salvador, the European Union, Honduras, Japan, Korea, Malaysia, Mexico, New Zealand, Philippines, the Russian Federation, Singapore, South Africa, Taiwan, Thailand, and the United States. Insect-resistant maize was grown in Argentina, Australia, Brazil, Canada, Chile, China, Colombia, Egypt, the European Union, Honduras, Japan, Korea, Malaysia, Mexico, New Zealand, Philippines, South Africa, Switzerland, Taiwan, the United States, and Uruguay.
In September 2000, up to $50 million worth of food products were recalled due to the presence of Starlink genetically modified corn, which had been approved only for animal consumption and had not been approved for human consumption, and was subsequently withdrawn from the market.
ORIGIN
Maize is the domesticated variant of teosinte. The two plants have dissimilar appearance, maize having a single tall stalk with multiple leaves and teosinte being a short, bushy plant. The difference between the two is largely controlled by differences in just two genes, called grassy tillers-1 (gt1, A0A317YEZ1) and teosinte branched-1 (tb1, Q93WI2).
Several theories had been proposed about the specific origin of maize in Mesoamerica:
It is a direct domestication of a Mexican annual teosinte, Zea mays ssp. parviglumis, native to the Balsas River valley in south-eastern Mexico, with up to 12% of its genetic material obtained from Zea mays ssp. mexicana through introgression.
It has been derived from hybridization between a small domesticated maize (a slightly changed form of a wild maize) and a teosinte of section Luxuriantes, either Z. luxurians or Z. diploperennis.
It has undergone two or more domestications either of a wild maize or of a teosinte. (The term "teosinte" describes all species and subspecies in the genus Zea, excluding Zea mays ssp. mays.)
It has evolved from a hybridization of Z. diploperennis by Tripsacum dactyloides.
In the late 1930s, Paul Mangelsdorf suggested that domesticated maize was the result of a hybridization event between an unknown wild maize and a species of Tripsacum, a related genus. This theory about the origin of maize has been refuted by modern genetic testing, which refutes Mangelsdorf's model and the fourth listed above.
The teosinte origin theory was proposed by the Russian botanist Nikolai Ivanovich Vavilov in 1931 and the later American Nobel Prize-winner George Beadle in 1932.: 10 It is supported experimentally and by recent studies of the plants' genomes. Teosinte and maize can cross-breed and produce fertile offspring. A number of questions remain concerning the species, among them:
how the immense diversity of the species of sect. Zea originated,
how the tiny archaeological specimens of 3500–2700 BC could have been selected from a teosinte, and
how domestication could have proceeded without leaving remains of teosinte or maize with teosintoid traits earlier than the earliest known until recently, dating from ca. 1100 BC.
The domestication of maize is of particular interest to researchers—archaeologists, geneticists, ethnobotanists, geographers, etc. The process is thought by some to have started 7,500 to 12,000 years ago. Research from the 1950s to 1970s originally focused on the hypothesis that maize domestication occurred in the highlands between the states of Oaxaca and Jalisco, because the oldest archaeological remains of maize known at the time were found there.
Connection with 'parviglumis' subspecies
Genetic studies, published in 2004 by John Doebley, identified Zea mays ssp. parviglumis, native to the Balsas River valley in Mexico's southwestern highlands, and also known as Balsas teosinte, as being the crop wild relative that is genetically most similar to modern maize. This was confirmed by further studies, which refined this hypothesis somewhat. Archaeobotanical studies, published in 2009, point to the middle part of the Balsas River valley as the likely location of early domestication; this river is not very long, so these locations are not very distant. Stone milling tools with maize residue have been found in an 8,700 year old layer of deposits in a cave not far from Iguala, Guerrero.
Doebley was part of the team that first published, in 2002, that maize had been domesticated only once, about 9,000 years ago, and then spread throughout the Americas.
A primitive corn was being grown in southern Mexico, Central America, and northern South America 7,000 years ago. Archaeological remains of early maize ears, found at Guila Naquitz Cave in the Oaxaca Valley, date back roughly 6,250 years; the oldest ears from caves near Tehuacan, Puebla, 5,450 B.P.
Maize pollen dated to 7,300 B.P. from San Andres, Tabasco, on the Caribbean coast has also been recovered.
As maize was introduced to new cultures, new uses were developed and new varieties selected to better serve in those preparations. Maize was the staple food, or a major staple – along with squash, Andean region potato, quinoa, beans, and amaranth – of most pre-Columbian North American, Mesoamerican, South American, and Caribbean cultures. The Mesoamerican civilization, in particular, was deeply interrelated with maize. Its traditions and rituals involved all aspects of maize cultivation – from the planting to the food preparation. Maize formed the Mesoamerican people's identity.
It is unknown what precipitated its domestication, because the edible portion of the wild variety is too small, and hard to obtain, to be eaten directly, as each kernel is enclosed in a very hard bivalve shell.
In 1939, George Beadle demonstrated that the kernels of teosinte are readily "popped" for human consumption, like modern popcorn. Some have argued it would have taken too many generations of selective breeding to produce large, compressed ears for efficient cultivation. However, studies of the hybrids readily made by intercrossing teosinte and modern maize suggest this objection is not well founded.
SPREADING TO THE NORTH
Around 4,500 ago, maize began to spread to the north; it was first cultivated in what is now the United States at several sites in New Mexico and Arizona, about 4,100 ago.
During the first millennium AD, maize cultivation spread more widely in the areas north. In particular, the large-scale adoption of maize agriculture and consumption in eastern North America took place about A.D. 900. Native Americans cleared large forest and grassland areas for the new crop.
In 2005, research by the USDA Forest Service suggested that the rise in maize cultivation 500 to 1,000 years ago in what is now the southeastern United States corresponded with a decline of freshwater mussels, which are very sensitive to environmental changes.
CULTIVATION
PLANTING
Because it is cold-intolerant, in the temperate zones maize must be planted in the spring. Its root system is generally shallow, so the plant is dependent on soil moisture. As a plant that uses C4 carbon fixation, maize is a considerably more water-efficient crop than plants that use C3 carbon fixation such as alfalfa and soybeans. Maize is most sensitive to drought at the time of silk emergence, when the flowers are ready for pollination. In the United States, a good harvest was traditionally predicted if the maize was "knee-high by the Fourth of July", although modern hybrids generally exceed this growth rate. Maize used for silage is harvested while the plant is green and the fruit immature. Sweet corn is harvested in the "milk stage", after pollination but before starch has formed, between late summer and early to mid-autumn. Field maize is left in the field until very late in the autumn to thoroughly dry the grain, and may, in fact, sometimes not be harvested until winter or even early spring. The importance of sufficient soil moisture is shown in many parts of Africa, where periodic drought regularly causes maize crop failure and consequent famine. Although it is grown mainly in wet, hot climates, it has been said to thrive in cold, hot, dry or wet conditions, meaning that it is an extremely versatile crop.
Maize was planted by the Native Americans in hills, in a complex system known to some as the Three Sisters. Maize provided support for beans, and the beans provided nitrogen derived from nitrogen-fixing rhizobia bacteria which live on the roots of beans and other legumes; and squashes provided ground cover to stop weeds and inhibit evaporation by providing shade over the soil. This method was replaced by single species hill planting where each hill 60–120 cm (2 ft 0 in–3 ft 11 in) apart was planted with three or four seeds, a method still used by home gardeners. A later technique was "checked maize", where hills were placed
1 m (40 in) apart in each direction, allowing cultivators to run through the field in two directions. In more arid lands, this was altered and seeds were planted in the bottom of 10–12 cm (4–4+1⁄2 in) deep furrows to collect water. Modern technique plants maize in rows which allows for cultivation while the plant is young, although the hill technique is still used in the maize fields of some Native American reservations. When maize is planted in rows, it also allows for planting of other crops between these rows to make more efficient use of land space.
In most regions today, maize grown in residential gardens is still often planted manually with a hoe, whereas maize grown commercially is no longer planted manually but rather is planted with a planter. In North America, fields are often planted in a two-crop rotation with a nitrogen-fixing crop, often alfalfa in cooler climates and soybeans in regions with longer summers. Sometimes a third crop, winter wheat, is added to the rotation.
Many of the maize varieties grown in the United States and Canada are hybrids. Often the varieties have been genetically modified to tolerate glyphosate or to provide protection against natural pests. Glyphosate is an herbicide which kills all plants except those with genetic tolerance. This genetic tolerance is very rarely found in nature.
In the midwestern United States, low-till or no-till farming techniques are usually used. In low-till, fields are covered once, maybe twice, with a tillage implement either ahead of crop planting or after the previous harvest. The fields are planted and fertilized. Weeds are controlled through the use of herbicides, and no cultivation tillage is done during the growing season. This technique reduces moisture evaporation from the soil, and thus provides more moisture for the crop. The technologies mentioned in the previous paragraph enable low-till and no-till farming. Weeds compete with the crop for moisture and nutrients, making them undesirable.
HARVESTING
Before the 20th century, all maize harvesting was by manual labour, by grazing, or by some combination of those. Whether the ears were hand-picked and the stover was grazed, or the whole plant was cut, gathered, and shocked, people and livestock did all the work. Between the 1890s and the 1970s, the technology of maize harvesting expanded greatly. Today, all such technologies, from entirely manual harvesting to entirely mechanized, are still in use to some degree, as appropriate to each farm's needs, although the thoroughly mechanized versions predominate, as they offer the lowest unit costs when scaled to large farm operations. For small farms, their unit cost can be too high, as their higher fixed cost cannot be amortized over as many units.[citation needed]
Before World War II, most maize in North America was harvested by hand. This involved a large number of workers and associated social events (husking or shucking bees). From the 1890s onward, some machinery became available to partially mechanize the processes, such as one- and two-row mechanical pickers (picking the ear, leaving the stover) and corn binders, which are reaper-binders designed specifically for maize (for example, Video on YouTube). The latter produce sheaves that can be shocked. By hand or mechanical picker, the entire ear is harvested, which then requires a separate operation of a maize sheller to remove the kernels from the ear. Whole ears of maize were often stored in corn cribs, and these whole ears are a sufficient form for some livestock feeding use. Today corn cribs with whole ears, and corn binders, are less common because most modern farms harvest the grain from the field with a combine and store it in bins. The combine with a corn head (with points and snap rolls instead of a reel) does not cut the stalk; it simply pulls the stalk down. The stalk continues downward and is crumpled into a mangled pile on the ground, where it usually is left to become organic matter for the soil. The ear of maize is too large to pass between slots in a plate as the snap rolls pull the stalk away, leaving only the ear and husk to enter the machinery. The combine separates the husk and the cob, keeping only the kernels.
When maize is a silage crop, the entire plant is usually chopped at once with a forage harvester (chopper) and ensiled in silos or polymer wrappers. Ensiling of sheaves cut by a corn binder was formerly common in some regions but has become uncommon. For storing grain in bins, the moisture of the grain must be sufficiently low to avoid spoiling. If the moisture content of the harvested grain is too high, grain dryers are used to reduce the moisture content by blowing heated air through the grain. This can require large amounts of energy in the form of combustible gases (propane or natural gas) and electricity to power the blowers.
PRODUCTION
Maize is widely cultivated throughout the world, and a greater weight of maize is produced each year than any other grain. In 2018, total world production was 1.15 billion tonnes, led by the United States with 34.2% of the total (table). China produced 22.4% of the global total.
UNITED STATES
In 2016, maize production was forecast to be over 380 million metric tons (15 billion bushels), an increase of 11% over 2014 American production. Based on conditions as of August 2016, the expected yield would be the highest ever for the United States. The area of harvested maize was forecast to be 35 million hectares (87 million acres), an increase of 7% over 2015. Maize is especially popular in Midwestern states such as Indiana, Iowa, and Illinois; in the latter, it was named the state's official grain in 2017.
STORAGE
Drying is vital to prevent or at least reduce mycotoxin contamination. Aspergillus and Fusarium spp. are the most common mycotoxin sources, but there are others. Altogether maize contaminants are so common, and this crop is so economically important, that maize mycotoxins are among the most important in agriculture in general.
USES
HUMAN FOOD
Maize and cornmeal (ground dried maize) constitute a staple food in many regions of the world. Maize is used to produce cornstarch, a common ingredient in home cooking and many industrialized food products. Maize starch can be hydrolyzed and enzymatically treated to produce syrups, particularly high fructose corn syrup, a sweetener; and also fermented and distilled to produce grain alcohol. Grain alcohol from maize is traditionally the source of Bourbon whiskey. Corn flour is used to make cornbread and other baked products.
In prehistoric times Mesoamerican women used a metate to process maize into ground cornmeal, allowing the preparation of foods that were more calorie dense than popcorn. After ceramic vessels were invented the Olmec people began to cook maize together with beans, improving the nutritional value of the staple meal. Although maize naturally contains niacin, an important nutrient, it was not bioavailable without the process of nixtamalization. The Maya used nixtamal meal to make varieties of porridges and tamales. The process was later used in the cuisine of the American South to prepare corn for grits and hominy.
Maize is a staple of Mexican cuisine. Masa (cornmeal treated with limewater) is the main ingredient for tortillas, atole and many other dishes of Central American food. It is the main ingredient of corn tortilla, tamales, pozole, atole and all the dishes based on them, like tacos, quesadillas, chilaquiles, enchiladas, tostadas and many more. In Mexico the fungus of maize, known as huitlacoche, is considered a delicacy.
Coarse maize meal is made into a thick porridge in many cultures: from the polenta of Italy, the angu of Brazil, the mămăligă of Romania, to cornmeal mush in the US (or hominy grits in the South) or the food called mieliepap in South Africa and sadza, nshima, ugali and other names in other parts of Africa. Introduced into Africa by the Portuguese in the 16th century, maize has become Africa's most important staple food crop. These are commonly eaten in the Southeastern United States, foods handed down from Native Americans, who called the dish sagamite.
Maize can also be harvested and consumed in the unripe state, when the kernels are fully grown but still soft. Unripe maize must usually be cooked to become palatable; this may be done by simply boiling or roasting the whole ears and eating the kernels right off the cob. Sweet corn, a genetic variety that is high in sugars and low in starch, is usually consumed in the unripe state. Such corn on the cob is a common dish in the United States, Canada, United Kingdom, Cyprus, some parts of South America, and the Balkans, but virtually unheard of in some European countries. Corn on the cob was hawked on the streets of early 19th-century New York City by poor, barefoot "Hot Corn Girls", who were thus the precursors of hot dog carts, churro wagons, and fruit stands seen on the streets of big cities today.
Within the United States, the usage of maize for human consumption constitutes only around 1/40th of the amount grown in the country. In the United States and Canada, maize is mostly grown to feed livestock, as forage, silage (made by fermentation of chopped green cornstalks), or grain. Maize meal is also a significant ingredient of some commercial animal food products.
NUTRITIONAL VALUE
Raw, yellow, sweet maize kernels are composed of 76% water, 19% carbohydrates, 3% protein, and 1% fat (table). In a 100-gram serving, maize kernels provide 86 calories and are a good source (10–19% of the Daily Value) of the B vitamins, thiamin, niacin (but see Pellagra warning below), pantothenic acid (B5) and folate (right table for raw, uncooked kernels, USDA Nutrient Database). In moderate amounts, they also supply dietary fiber and the essential minerals, magnesium and phosphorus whereas other nutrients are in low amounts (table).
Maize has suboptimal amounts of the essential amino acids tryptophan and lysine, which accounts for its lower status as a protein source. However, the proteins of beans and legumes complement those of maize.
FEED AND FODDER FOR LIVESTOCK
Maize is a major source of both grain feed and fodder for livestock. It is fed to the livestock in various ways. When it is used as a grain crop, the dried kernels are used as feed. They are often kept on the cob for storage in a corn crib, or they may be shelled off for storage in a grain bin. The farm that consumes the feed may produce it, purchase it on the market, or some of both. When the grain is used for feed, the rest of the plant (the corn stover) can be used later as fodder, bedding (litter), or soil amendment. When the whole maize plant (grain plus stalks and leaves) is used for fodder, it is usually chopped all at once and ensilaged, as digestibility and palatability are higher in the ensilaged form than in the dried form. Maize silage is one of the most valuable forages for ruminants. Before the advent of widespread ensilaging, it was traditional to gather the corn into shocks after harvesting, where it dried further. With or without a subsequent move to the cover of a barn, it was then stored for weeks to several months until fed to the livestock. Today ensilaging can occur not only in siloes but also in silage wrappers. However, in the tropics, maize can be harvested year-round and fed as green forage to the animals.
CHEMICALS
Starch from maize can also be made into plastics, fabrics, adhesives, and many other chemical products.
The corn steep liquor, a plentiful watery byproduct of maize wet milling process, is widely used in the biochemical industry and research as a culture medium to grow many kinds of microorganisms.
Chrysanthemin is found in purple corn and is used as a food coloring.
BIO-FUEL
"Feed maize" is being used increasingly for heating; specialized corn stoves (similar to wood stoves) are available and use either feed maize or wood pellets to generate heat. Maize cobs are also used as a biomass fuel source. Maize is relatively cheap and home-heating furnaces have been developed which use maize kernels as a fuel. They feature a large hopper that feeds the uniformly sized maize kernels (or wood pellets or cherry pits) into the fire.[citation needed]
Maize is increasingly used as a feedstock for the production of ethanol fuel. When considering where to construct an ethanol plant, one of the site selection criteria is to ensure there is locally available feedstock. Ethanol is mixed with gasoline to decrease the amount of pollutants emitted when used to fuel motor vehicles. High fuel prices in mid-2007 led to higher demand for ethanol, which in turn led to higher prices paid to farmers for maize. This led to the 2007 harvest being one of the most profitable maize crops in modern history for farmers. Because of the relationship between fuel and maize, prices paid for the crop now tend to track the price of oil.
The price of food is affected to a certain degree by the use of maize for biofuel production. The cost of transportation, production, and marketing are a large portion (80%) of the price of food in the United States. Higher energy costs affect these costs, especially transportation. The increase in food prices the consumer has been seeing is mainly due to the higher energy cost. The effect of biofuel production on other food crop prices is indirect. Use of maize for biofuel production increases the demand, and therefore price of maize. This, in turn, results in farm acreage being diverted from other food crops to maize production. This reduces the supply of the other food crops and increases their prices.
Maize is widely used in Germany as a feedstock for biogas plants. Here the maize is harvested, shredded then placed in silage clamps from which it is fed into the biogas plants. This process makes use of the whole plant rather than simply using the kernels as in the production of fuel ethanol.
A biomass gasification power plant in Strem near Güssing, Burgenland, Austria, began in 2005. Research is being done to make diesel out of the biogas by the Fischer Tropsch method.
Increasingly, ethanol is being used at low concentrations (10% or less) as an additive in gasoline (gasohol) for motor fuels to increase the octane rating, lower pollutants, and reduce petroleum use (what is nowadays also known as "biofuels" and has been generating an intense debate regarding the human beings' necessity of new sources of energy, on the one hand, and the need to maintain, in regions such as Latin America, the food habits and culture which has been the essence of civilizations such as the one originated in Mesoamerica; the entry, January 2008, of maize among the commercial agreements of NAFTA has increased this debate, considering the bad labor conditions of workers in the fields, and mainly the fact that NAFTA "opened the doors to the import of maize from the United States, where the farmers who grow it receive multimillion-dollar subsidies and other government supports. ... According to OXFAM UK, after NAFTA went into effect, the price of maize in Mexico fell 70% between 1994 and 2001. The number of farm jobs dropped as well: from 8.1 million in 1993 to 6.8 million in 2002. Many of those who found themselves without work were small-scale maize growers."). However, introduction in the northern latitudes of the US of tropical maize for biofuels, and not for human or animal consumption, may potentially alleviate this.
COMMODITY
Maize is bought and sold by investors and price speculators as a tradable commodity using corn futures contracts. These "futures" are traded on the Chicago Board of Trade (CBOT) under ticker symbol C. They are delivered every year in March, May, July, September, and December.
ORNAMENTAL AND OTHER USES
Some forms of the plant are occasionally grown for ornamental use in the garden. For this purpose, variegated and colored leaf forms as well as those with colorful ears are used.
Corncobs can be hollowed out and treated to make inexpensive smoking pipes, first manufactured in the United States in 1869.
An unusual use for maize is to create a "corn maze" (or "maize maze") as a tourist attraction. The idea of a maize maze was introduced by the American Maze Company who created a maze in Pennsylvania in 1993. Traditional mazes are most commonly grown using yew hedges, but these take several years to mature. The rapid growth of a field of maize allows a maze to be laid out using GPS at the start of a growing season and for the maize to grow tall enough to obstruct a visitor's line of sight by the start of the summer. In Canada and the US, these are popular in many farming communities.
Maize kernels can be used in place of sand in a sandboxlike enclosure for children's play.
Stigmas from female maize flowers, popularly called corn silk, are sold as herbal supplements.
Maize is used as a fish bait, called "dough balls". It is particularly popular in Europe for coarse fishing.
Additionally, feed corn is sometimes used by hunters to bait animals such as deer or wild hogs.
UNITED STATES USAGE BREAKDOWN
The breakdown of usage of the 12.1-billion-bushel (307-million-tonne) 2008 US maize crop was as follows, according to the World Agricultural Supply and Demand Estimates Report by the USDA.In the US since 2009/2010, maize feedstock use for ethanol production has somewhat exceeded direct use for livestock feed; maize use for fuel ethanol was 5,130 million bushels (130 million tonnes) in the 2013/2014 marketing year.A fraction of the maize feedstock dry matter used for ethanol production is usefully recovered as DDGS (dried distillers grains with solubles). In the 2010/2011 marketing year, about 29.1 million tonnes of DDGS were fed to US livestock and poultry. Because starch utilization in fermentation for ethanol production leaves other grain constituents more concentrated in the residue, the feed value per kg of DDGS, with regard to ruminant-metabolizable energy and protein, exceeds that of the grain. Feed value for monogastric animals, such as swine and poultry, is somewhat lower than for ruminants.
HAZARDS
PELLAGRA
When maize was first introduced into farming systems other than those used by traditional native-American peoples, it was generally welcomed with enthusiasm for its productivity. However, a widespread problem of malnutrition soon arose wherever maize was introduced as a staple food. This was a mystery, since these types of malnutrition were not normally seen among the indigenous Americans, for whom maize was the principal staple food.
It was eventually discovered that the indigenous Americans had learned to soak maize in alkali — water (the process now known as nixtamalization) — made with ashes and lime (calcium oxide) since at least 1200–1500 BC by Mesoamericans. They did this to liberate the corn hulls, but (unbeknownst to natives or colonists) it coincidentally liberates the B-vitamin niacin, the lack of which was the underlying cause of the condition known as pellagra.
Maize was introduced into the diet of non-indigenous Americans without the necessary cultural knowledge acquired over thousands of years in the Americas. In the late 19th century, pellagra reached epidemic proportions in parts of the southern US, as medical researchers debated two theories for its origin: the deficiency theory (which was eventually shown to be true) said that pellagra was due to a deficiency of some nutrient, and the germ theory said that pellagra was caused by a germ transmitted by stable flies. A third theory, promoted by the eugenicist Charles Davenport, held that people only contracted pellagra if they were susceptible to it due to certain "constitutional, inheritable" traits of the affected individual.
Once alkali processing and dietary variety were understood and applied, pellagra disappeared in the developed world. The development of high lysine maize and the promotion of a more balanced diet have also contributed to its demise. Pellagra still exists today in food-poor areas and refugee camps where people survive on donated maize.
ALLERGY
Maize contains lipid transfer protein, an indigestible protein that survives cooking. This protein has been linked to a rare and understudied allergy to maize in humans. The allergic reaction can cause skin rash, swelling or itching of mucous membranes, diarrhea, vomiting, asthma and, in severe cases, anaphylaxis. It is unclear how common this allergy is in the general population.
MYCOTOXINS
Fungicide application does not reduce fungal growth or mycotoxin dramatically, although it can be a part of a successful reduction strategy. Among the most common toxins are those produced by Aspergillus and Fusarium spp. The most common toxins are aflatoxins, fumonisins, zearalenone, and ochratoxin A. Bt maize discourages insect vectors and by so doing it dramatically reduces concentrations of fumonisins, significantly reduces aflatoxins, but only mildly reduces others.
ART
Maize has been an essential crop in the Andes since the pre-Columbian era. The Moche culture from Northern Peru made ceramics from earth, water, and fire. This pottery was a sacred substance, formed in significant shapes and used to represent important themes. Maize was represented anthropomorphically as well as naturally.
In the United States, maize ears along with tobacco leaves are carved into the capitals of columns in the United States Capitol building. Maize itself is sometimes used for temporary architectural detailing when the intent is to celebrate the fall season, local agricultural productivity and culture. Bundles of dried maize stalks are often displayed along with pumpkins, gourds and straw in autumnal displays outside homes and businesses. A well-known example of architectural use is the Corn Palace in Mitchell, South Dakota, which uses cobs and ears of colored maize to implement a mural design that is recycled annually. Another well-known example is the Field of Corn sculpture in Dublin, Ohio, where hundreds of concrete ears of corn stand in a grassy field.
A maize stalk with two ripe ears is depicted on the reverse of the Croatian 1 lipa coin, minted since 1993.
WIKIPEDIA
Les bactéries et leur rôle dans l'anatomie et l'histologie pathologiques des maladies infectieuses :
Paris :F. Alcan,1885.
Ipê Amarelo, Tabebuia [chrysotricha or ochracea].
Ipê-amarelo em Brasília, Brasil.
This tree is in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Copyright - All Rights Reserved - Black Diamond Images
Waipoua Forest,North Island NZ
Agathis australis - New Zealand Kauri,Kauri,Southern Kauri
Family : Araucariaceae
At between 2000 and 3000 years old Te Matua Ngahere is the 2nd Largest Agathis australis -(Southern Kauri) in New Zealand and effectively - the world, having the
biggest Kauri girth of - 16.41m and the 2nd biggest trunk volume - 208.1Cubic Metres. Compared to the tallest Kauri,it is just over half Tane Mahuta's
height - 29.9m (Trunk Height - 10.21m.)
Although not as tall as Tane Mahuta (51.5m) "Lord of the Forest", Te Matua Ngahere "Father of the Forest" is much broader and stouter.
At 208.1 Cubic Metres compared to Tane Mahuta's massive volume of 244.5 cubic metres Te Matua Ngahere is second in overal size to Tane Mahuta.
Te Matua Ngahere suffered serious crown damage in 2007 after a storm.
Storm takes centre of Te Matua Ngahere
Regretably in recent times New Zealand's iconic Agathis australis trees are in trouble from an introduced pathogenic fungus called Phytophthora - left unchecked it has the potential to wipe the species out.
This is an amazing must read article which details the sad history of Australia's tallest trees
Maize (/meɪz/ MAYZ; Zea mays subsp. mays, from Spanish: maíz after Taino: mahiz), also known as corn (North American and Australian English), is a cereal grain first domesticated by indigenous peoples in southern Mexico about 10,000 years ago. The leafy stalk of the plant produces pollen inflorescences and separate ovuliferous inflorescences called ears that yield kernels or seeds, which are fruits.
Maize has become a staple food in many parts of the world, with the total production of maize surpassing that of wheat or rice. In addition to being consumed directly by humans (often in the form of masa), maize is also used for corn ethanol, animal feed and other maize products, such as corn starch and corn syrup. The six major types of maize are dent corn, flint corn, pod corn, popcorn, flour corn, and sweet corn. Sugar-rich varieties called sweet corn are usually grown for human consumption as kernels, while field corn varieties are used for animal feed, various corn-based human food uses (including grinding into cornmeal or masa, pressing into corn oil, and fermentation and distillation into alcoholic beverages like bourbon whiskey), and as chemical feedstocks. Maize is also used in making ethanol and other biofuels.
Maize is widely cultivated throughout the world, and a greater weight of maize is produced each year than any other grain. In 2014, total world production was 1.04 billion tonnes. Maize is the most widely grown grain crop throughout the Americas, with 361 million metric tons grown in the United States alone in 2014. Genetically modified maize made up 85% of the maize planted in the United States in 2009. Subsidies in the United States help to account for its high level of cultivation of maize and its position as the largest producer in the world.
HISTORY
PRE-COLUMBIAN DEVELOPMENT
Maize is a cultigen; human intervention is required for it to propagate. Whether or not the kernels fall off the cob on their own is a key piece of evidence used in archaeology to distinguish domesticated maize from its naturally-propagating teosinte ancestor. Genetic evidence can also be used to determine when various lineages split.
Most historians believe maize was domesticated in the Tehuacán Valley of Mexico. Recent research in the early 21st century has modified this view somewhat; scholars now indicate the adjacent Balsas River Valley of south-central Mexico as the center of domestication.
An influential 2002 study by Matsuoka et al. has demonstrated that, rather than the multiple independent domestications model, all maize arose from a single domestication in southern Mexico about 9,000 years ago. The study also demonstrated that the oldest surviving maize types are those of the Mexican highlands. Later, maize spread from this region over the Americas along two major paths. This is consistent with a model based on the archaeological record suggesting that maize diversified in the highlands of Mexico before spreading to the lowlands.
Archaeologist Dolores Piperno has said:
A large corpus of data indicates that [maize] was dispersed into lower Central America by 7600 BP [5600 BC] and had moved into the inter-Andean valleys of Colombia between 7000 and 6000 BP [5000–4000 BC].
— Dolores Piperno, The Origins of Plant Cultivation and Domestication in the New World Tropics: Patterns, Process, and New Developments
Since then, even earlier dates have been published.
According to a genetic study by Embrapa, corn cultivation was introduced in South America from Mexico, in two great waves: the first, more than 6000 years ago, spread through the Andes. Evidence of cultivation in Peru has been found dating to about 6700 years ago. The second wave, about 2000 years ago, through the lowlands of South America.
The earliest maize plants grew only small, 25-millimetre-long (1 in) corn cobs, and only one per plant. In Jackson Spielvogel's view, many centuries of artificial selection (rather than the current view that maize was exploited by interplanting with teosinte) by the indigenous people of the Americas resulted in the development of maize plants capable of growing several cobs per plant, which were usually several centimetres/inches long each. The Olmec and Maya cultivated maize in numerous varieties throughout Mesoamerica; they cooked, ground and processed it through nixtamalization. It was believed that beginning about 2500 BC, the crop spread through much of the Americas. Research of the 21st century has established even earlier dates. The region developed a trade network based on surplus and varieties of maize crops.
Mapuches of south-central Chile cultivated maize along with quinoa and potatoes in pre-Hispanic times; however, potato was the staple food of most Mapuches, "specially in the southern and coastal [Mapuche] territories where maize did not reach maturity". Before the expansion of the Inca Empire maize was traded and transported as far south as 40°19' S in Melinquina, Lácar Department. In that location maize remains were found inside pottery dated to 730 ± 80 BP and 920 ± 60 BP. Probably this maize was brought across the Andes from Chile. The presence of maize in Guaitecas Archipelago (43°55' S), the southernmost outpost of pre-Hispanic agriculture, is reported by early Spanish explorers. However the Spanish may have misidentified the plant.
COLUMBIAN EXCHANGE
After the arrival of Europeans in 1492, Spanish settlers consumed maize, and explorers and traders carried it back to Europe and introduced it to other countries. Spanish settlers far preferred wheat bread to maize, cassava, or potatoes. Maize flour could not be substituted for wheat for communion bread, since in Christian belief only wheat could undergo transubstantiation and be transformed into the body of Christ. Some Spaniards worried that by eating indigenous foods, which they did not consider nutritious, they would weaken and risk turning into Indians. "In the view of Europeans, it was the food they ate, even more than the environment in which they lived, that gave Amerindians and Spaniards both their distinctive physical characteristics and their characteristic personalities." Despite these worries, Spaniards did consume maize. Archeological evidence from Florida sites indicate they cultivated it as well.
Maize spread to the rest of the world because of its ability to grow in diverse climates. It was cultivated in Spain just a few decades after Columbus's voyages and then spread to Italy, West Africa and elsewhere. Widespread cultivation most likely began in southern Spain in 1525, after which it quickly spread to the rest of the Spanish Empire including its territories in Italy (and, from there, to other Italian states). Maize had many advantages over wheat and barley; it yielded two and a half times the food energy per unit cultivated area, could be harvested in successive years from the same plot of land, and grew in wildly varying altitudes and climates, from relatively dry regions with only 250 mm (10 in) of annual rainfall to damp regions with over 5,000 mm (200 in). By the 17th century it was a common peasant food in Southwestern Europe, including Portugal, Spain, southern France, and Italy. By the 18th century, it was the chief food of the southern French and Italian peasantry, especially in the form of polenta in Italy.
Names
The word maize derives from the Spanish form of the indigenous Taíno word for the plant, mahiz. It is known by other names around the world.
The word "corn" outside the US, Canada, Australia, and New Zealand refers to any cereal crop, its meaning understood to vary geographically to refer to the local staple. In the United States, Canada, Australia, and New Zealand, corn primarily means maize; this usage started as a shortening of "Indian corn". "Indian corn" primarily means maize (the staple grain of indigenous Americans), but can refer more specifically to multicolored "flint corn" used for decoration.
In places outside the US, Canada, Australia, and New Zealand, corn often refers to maize in culinary contexts. The narrower meaning is usually indicated by some additional word, as in sweet corn, sweetcorn, corn on the cob, baby corn, the puffed confection known as popcorn and the breakfast cereal known as corn flakes.
In Southern Africa, maize is commonly called mielie (Afrikaans) or mealie (English), words derived from the Portuguese word for maize, milho.
Maize is preferred in formal, scientific, and international usage because it refers specifically to this one grain, unlike corn, which has a complex variety of meanings that vary by context and geographic region. Maize is used by agricultural bodies and research institutes such as the FAO and CSIRO. National agricultural and industry associations often include the word maize in their name even in English-speaking countries where the local, informal word is something other than maize; for example, the Maize Association of Australia, the Indian Maize Development Association, the Kenya Maize Consortium and Maize Breeders Network, the National Maize Association of Nigeria, the Zimbabwe Seed Maize Association.
STRUCTURE AND PHYSIOLOGY
The maize plant is often 3 m (10 ft) in height, though some natural strains can grow 13 m (43 ft). The stem is commonly composed of 20 internodes of 18 cm (7 in) length. The leaves arise from the nodes, alternately on opposite sides on the stalk. A leaf, which grows from each node, is generally 9 cm (3+1⁄2 in) in width and 120 cm (3 ft 11 in) in length.
Ears develop above a few of the leaves in the midsection of the plant, between the stem and leaf sheath, elongating by around 3 mm (1⁄8 in) per day, to a length of 18 cm (7 in) with 60 cm (24 in) being the maximum alleged in the subspecies. They are female inflorescences, tightly enveloped by several layers of ear leaves commonly called husks. Certain varieties of maize have been bred to produce many additional developed ears. These are the source of the "baby corn" used as a vegetable in Asian cuisine.
The apex of the stem ends in the tassel, an inflorescence of male flowers. When the tassel is mature and conditions are suitably warm and dry, anthers on the tassel dehisce and release pollen. Maize pollen is anemophilous (dispersed by wind), and because of its large settling velocity, most pollen falls within a few meters of the tassel.
Elongated stigmas, called silks, emerge from the whorl of husk leaves at the end of the ear. They are often pale yellow and 18 cm (7 in) in length, like tufts of hair in appearance. At the end of each is a carpel, which may develop into a "kernel" if fertilized by a pollen grain. The pericarp of the fruit is fused with the seed coat referred to as "caryopsis", typical of the grasses, and the entire kernel is often referred to as the "seed". The cob is close to a multiple fruit in structure, except that the individual fruits (the kernels) never fuse into a single mass. The grains are about the size of peas, and adhere in regular rows around a white, pithy substance, which forms the ear. The maximum size of kernels is reputedly 2.5 cm (1 in). An ear commonly holds 600 kernels. They are of various colors: blackish, bluish-gray, purple, green, red, white and yellow. When ground into flour, maize yields more flour with much less bran than wheat does. It lacks the protein gluten of wheat and, therefore, makes baked goods with poor rising capability. A genetic variant that accumulates more sugar and less starch in the ear is consumed as a vegetable and is called sweet corn. Young ears can be consumed raw, with the cob and silk, but as the plant matures (usually during the summer months), the cob becomes tougher and the silk dries to inedibility. By the end of the growing season, the kernels dry out and become difficult to chew without cooking them tender first in boiling water.
Planting density affects multiple aspects of maize. Modern farming techniques in developed countries usually rely on dense planting, which produces one ear per stalk. Stands of silage maize are yet denser,[citation needed] and achieve a lower percentage of ears and more plant matter.
Maize is a facultative short-day plant and flowers in a certain number of growing degree days > 10 °C (50 °F) in the environment to which it is adapted. The magnitude of the influence that long nights have on the number of days that must pass before maize flowers is genetically prescribed and regulated by the phytochrome system.
Photoperiodicity can be eccentric in tropical cultivars such that the long days characteristic of higher latitudes allow the plants to grow so tall that they do not have enough time to produce seed before being killed by frost. These attributes, however, may prove useful in using tropical maize for biofuels.
Immature maize shoots accumulate a powerful antibiotic substance, 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA). DIMBOA is a member of a group of hydroxamic acids (also known as benzoxazinoids) that serve as a natural defense against a wide range of pests, including insects, pathogenic fungi and bacteria. DIMBOA is also found in related grasses, particularly wheat. A maize mutant (bx) lacking DIMBOA is highly susceptible to attack by aphids and fungi. DIMBOA is also responsible for the relative resistance of immature maize to the European corn borer (family Crambidae). As maize matures, DIMBOA levels and resistance to the corn borer decline.
Because of its shallow roots, maize is susceptible to droughts, intolerant of nutrient-deficient soils, and prone to be uprooted by severe winds.
While yellow maizes derive their color from lutein and zeaxanthin, in red-colored maizes, the kernel coloration is due to anthocyanins and phlobaphenes. These latter substances are synthesized in the flavonoids synthetic pathway from polymerization of flavan-4-ols by the expression of maize pericarp color1 (p1) gene which encodes an R2R3 myb-like transcriptional activator of the A1 gene encoding for the dihydroflavonol 4-reductase (reducing dihydroflavonols into flavan-4-ols) while another gene (Suppressor of Pericarp Pigmentation 1 or SPP1) acts as a suppressor. The p1 gene encodes an Myb-homologous transcriptional activator of genes required for biosynthesis of red phlobaphene pigments, while the P1-wr allele specifies colorless kernel pericarp and red cobs, and unstable factor for orange1 (Ufo1) modifies P1-wr expression to confer pigmentation in kernel pericarp, as well as vegetative tissues, which normally do not accumulate significant amounts of phlobaphene pigments. The maize P gene encodes a Myb homolog that recognizes the sequence CCT/AACC, in sharp contrast with the C/TAACGG bound by vertebrate Myb proteins.
The ear leaf is the leaf most closely associated with a particular developing ear. This leaf and above contribute 70% to 75% to 90% of grain fill. Therefore fungicide application is most important in that region in most disease environments.
ABNORMAL FLOWERS
Maize flowers may sometimes exhibit mutations that lead to the formation of female flowers in the tassel. These mutations, ts4 and Ts6, prohibit the development of the stamen while simultaneously promoting pistil development. This may cause inflorescences containing both male and female flowers, or hermaphrodite flowers.
GENETICS
Maize is an annual grass in the family Gramineae, which includes such plants as wheat, rye, barley, rice, sorghum, and sugarcane. There are two major species of the genus Zea (out of six total): Zea mays (maize) and Zea diploperennis, which is a perennial type of teosinte. The annual teosinte variety called Zea mays mexicana is the closest botanical relative to maize. It still grows in the wild as an annual in Mexico and Guatemala.
Many forms of maize are used for food, sometimes classified as various subspecies related to the amount of starch each has:
Flour corn: Zea mays var. amylacea
Popcorn: Zea mays var. everta
Dent corn : Zea mays var. indentata
Flint corn: Zea mays var. indurata
Sweet corn: Zea mays var. saccharata and Zea mays var. rugosa
Waxy corn: Zea mays var. ceratina
Amylomaize: Zea mays
Pod corn: Zea mays var. tunicata Larrañaga ex A. St. Hil.
Striped maize: Zea mays var. japonica
This system has been replaced (though not entirely displaced) over the last 60 years by multivariable classifications based on ever more data. Agronomic data were supplemented by botanical traits for a robust initial classification, then genetic, cytological, protein and DNA evidence was added. Now, the categories are forms (little used), races, racial complexes, and recently branches.
Maize is a diploid with 20 chromosomes (n=10). The combined length of the chromosomes is 1500 cM. Some of the maize chromosomes have what are known as "chromosomal knobs": highly repetitive heterochromatic domains that stain darkly. Individual knobs are polymorphic among strains of both maize and teosinte.
Barbara McClintock used these knob markers to validate her transposon theory of "jumping genes", for which she won the 1983 Nobel Prize in Physiology or Medicine. Maize is still an important model organism for genetics and developmental biology today.
The centromeres have two types of structural components, both of which are found only in the centromeres: Large arrays of CentC, a short satellite DNA; and a few of a family of retrotransposons. The B chromosome, unlike the others, contains an additional repeat which extends into neighboring areas of the chromosome. Centromeres can accidentally shrink during division and still function, although it is thought this will fail if it shrinks below a few hundred kilobase. Kinetochores contain RNA originating from centromeres. Centromere regions can become inactive, and can continue in that state if the chromosome still has another active one.
The Maize Genetics Cooperation Stock Center, funded by the USDA Agricultural Research Service and located in the Department of Crop Sciences at the University of Illinois at Urbana-Champaign, is a stock center of maize mutants. The total collection has nearly 80,000 samples. The bulk of the collection consists of several hundred named genes, plus additional gene combinations and other heritable variants. There are about 1000 chromosomal aberrations (e.g., translocations and inversions) and stocks with abnormal chromosome numbers (e.g., tetraploids). Genetic data describing the maize mutant stocks as well as myriad other data about maize genetics can be accessed at MaizeGDB, the Maize Genetics and Genomics Database.
In 2005, the US National Science Foundation (NSF), Department of Agriculture (USDA) and the Department of Energy (DOE) formed a consortium to sequence the B73 maize genome. The resulting DNA sequence data was deposited immediately into GenBank, a public repository for genome-sequence data. Sequences and genome annotations have also been made available throughout the project's lifetime at the project's official site.
Primary sequencing of the maize genome was completed in 2008. On November 20, 2009, the consortium published results of its sequencing effort in Science. The genome, 85% of which is composed of transposons, was found to contain 32,540 genes (By comparison, the human genome contains about 2.9 billion bases and 26,000 genes). Much of the maize genome has been duplicated and reshuffled by helitrons—group of rolling circle transposons.
In Z. mays and various other angiosperms the MADS-box motif is involved in floral development. Early study in several angiosperm models including Z. mays was the beginning of research into the molecular evolution of floral structure in general, as well as their role in nonflowering plants.
EVOLUTION
As with many plants and animals, Z. mays has a positive correlation between effective population size and the magnitude of selection pressure. Z. m. having an EPS of ~650,000, it clusters with others of about the same EPS, and has 79% of its amino acid sites under selection.
Recombination is a significant source of diversity in Z. mays. (Note that this finding supersedes previous studies which showed no such correlation.)
This recombination/diversity effect is seen throughout plants but is also found to not occur – or not as strongly – in regions of high gene density. This is likely the reason that domesticated Z. mays has not seen as much of an increase in diversity within areas of higher density as in regions of lower density, although there is more evidence in other plants.
Some lines of maize have undergone ancient polyploidy events, starting 11m years ago. Over that time ~72% of polyploid duplicated genes have been retained, which is higher than other plants with older polyploidy events. Thus maize may be due to lose more duplicate genes as time goes along, similar to the course followed by the genomes of other plants. If so - if gene loss has merely not occurred yet - that could explain the lack of observed positive selection and lower negative selection which are observed in otherwise similar plants, i.e. also naturally outcrossing and with similar effective population sizes.
Ploidy does not appear to influence EPS or magnitude of selection effect in maize.
BREEDING
Maize reproduces sexually each year. This randomly selects half the genes from a given plant to propagate to the next generation, meaning that desirable traits found in the crop (like high yield or good nutrition) can be lost in subsequent generations unless certain techniques are used.
Maize breeding in prehistory resulted in large plants producing large ears. Modern breeding began with individuals who selected highly productive varieties in their fields and then sold seed to other farmers. James L. Reid was one of the earliest and most successful developing Reid's Yellow Dent in the 1860s. These early efforts were based on mass selection. Later breeding efforts included ear to row selection (C. G. Hopkins c. 1896), hybrids made from selected inbred lines (G. H. Shull, 1909), and the highly successful double cross hybrids using four inbred lines (D. F. Jones c. 1918, 1922). University supported breeding programs were especially important in developing and introducing modern hybrids. By the 1930s, companies such as Pioneer devoted to production of hybrid maize had begun to influence long-term development. Internationally important seed banks such as the International Maize and Wheat Improvement Center (CIMMYT) and the US bank at the Maize Genetics Cooperation Stock Center University of Illinois at Urbana-Champaign maintain germplasm important for future crop development.
Since the 1940s the best strains of maize have been first-generation hybrids made from inbred strains that have been optimized for specific traits, such as yield, nutrition, drought, pest and disease tolerance. Both conventional cross-breeding and genetic modification have succeeded in increasing output and reducing the need for cropland, pesticides, water and fertilizer. There is conflicting evidence to support the hypothesis that maize yield potential has increased over the past few decades. This suggests that changes in yield potential are associated with leaf angle, lodging resistance, tolerance of high plant density, disease/pest tolerance, and other agronomic traits rather than increase of yield potential per individual plant.
Tropical landraces remain an important and underutilized source of resistance alleles for for disease and for herbivores. Notable discoveries of rare alleles for this purpose were made by Dao et al 2014 and Sood et al 2014.
GLOBAL PROGRAM
CIMMYT operates a conventional breeding program to provide optimized strains. The program began in the 1980s. Hybrid seeds are distributed in Africa by the Drought Tolerant Maize for Africa project.
GENETIC MODIFICATION
Genetically modified (GM) maize was one of the 26 GM crops grown commercially in 2016. The vast majority of this is Bt maize. Grown since 1997 in the United States and Canada, 92% of the US maize crop was genetically modified in 2016 and 33% of the worldwide maize crop was GM in 2016. As of 2011, Herbicide-tolerant maize varieties were grown in Argentina, Australia, Brazil, Canada, China, Colombia, El Salvador, the European Union, Honduras, Japan, Korea, Malaysia, Mexico, New Zealand, Philippines, the Russian Federation, Singapore, South Africa, Taiwan, Thailand, and the United States. Insect-resistant maize was grown in Argentina, Australia, Brazil, Canada, Chile, China, Colombia, Egypt, the European Union, Honduras, Japan, Korea, Malaysia, Mexico, New Zealand, Philippines, South Africa, Switzerland, Taiwan, the United States, and Uruguay.
In September 2000, up to $50 million worth of food products were recalled due to the presence of Starlink genetically modified corn, which had been approved only for animal consumption and had not been approved for human consumption, and was subsequently withdrawn from the market.
ORIGIN
Maize is the domesticated variant of teosinte. The two plants have dissimilar appearance, maize having a single tall stalk with multiple leaves and teosinte being a short, bushy plant. The difference between the two is largely controlled by differences in just two genes, called grassy tillers-1 (gt1, A0A317YEZ1) and teosinte branched-1 (tb1, Q93WI2).
Several theories had been proposed about the specific origin of maize in Mesoamerica:
It is a direct domestication of a Mexican annual teosinte, Zea mays ssp. parviglumis, native to the Balsas River valley in south-eastern Mexico, with up to 12% of its genetic material obtained from Zea mays ssp. mexicana through introgression.
It has been derived from hybridization between a small domesticated maize (a slightly changed form of a wild maize) and a teosinte of section Luxuriantes, either Z. luxurians or Z. diploperennis.
It has undergone two or more domestications either of a wild maize or of a teosinte. (The term "teosinte" describes all species and subspecies in the genus Zea, excluding Zea mays ssp. mays.)
It has evolved from a hybridization of Z. diploperennis by Tripsacum dactyloides.
In the late 1930s, Paul Mangelsdorf suggested that domesticated maize was the result of a hybridization event between an unknown wild maize and a species of Tripsacum, a related genus. This theory about the origin of maize has been refuted by modern genetic testing, which refutes Mangelsdorf's model and the fourth listed above.
The teosinte origin theory was proposed by the Russian botanist Nikolai Ivanovich Vavilov in 1931 and the later American Nobel Prize-winner George Beadle in 1932.: 10 It is supported experimentally and by recent studies of the plants' genomes. Teosinte and maize can cross-breed and produce fertile offspring. A number of questions remain concerning the species, among them:
how the immense diversity of the species of sect. Zea originated,
how the tiny archaeological specimens of 3500–2700 BC could have been selected from a teosinte, and
how domestication could have proceeded without leaving remains of teosinte or maize with teosintoid traits earlier than the earliest known until recently, dating from ca. 1100 BC.
The domestication of maize is of particular interest to researchers—archaeologists, geneticists, ethnobotanists, geographers, etc. The process is thought by some to have started 7,500 to 12,000 years ago. Research from the 1950s to 1970s originally focused on the hypothesis that maize domestication occurred in the highlands between the states of Oaxaca and Jalisco, because the oldest archaeological remains of maize known at the time were found there.
Connection with 'parviglumis' subspecies
Genetic studies, published in 2004 by John Doebley, identified Zea mays ssp. parviglumis, native to the Balsas River valley in Mexico's southwestern highlands, and also known as Balsas teosinte, as being the crop wild relative that is genetically most similar to modern maize. This was confirmed by further studies, which refined this hypothesis somewhat. Archaeobotanical studies, published in 2009, point to the middle part of the Balsas River valley as the likely location of early domestication; this river is not very long, so these locations are not very distant. Stone milling tools with maize residue have been found in an 8,700 year old layer of deposits in a cave not far from Iguala, Guerrero.
Doebley was part of the team that first published, in 2002, that maize had been domesticated only once, about 9,000 years ago, and then spread throughout the Americas.
A primitive corn was being grown in southern Mexico, Central America, and northern South America 7,000 years ago. Archaeological remains of early maize ears, found at Guila Naquitz Cave in the Oaxaca Valley, date back roughly 6,250 years; the oldest ears from caves near Tehuacan, Puebla, 5,450 B.P.
Maize pollen dated to 7,300 B.P. from San Andres, Tabasco, on the Caribbean coast has also been recovered.
As maize was introduced to new cultures, new uses were developed and new varieties selected to better serve in those preparations. Maize was the staple food, or a major staple – along with squash, Andean region potato, quinoa, beans, and amaranth – of most pre-Columbian North American, Mesoamerican, South American, and Caribbean cultures. The Mesoamerican civilization, in particular, was deeply interrelated with maize. Its traditions and rituals involved all aspects of maize cultivation – from the planting to the food preparation. Maize formed the Mesoamerican people's identity.
It is unknown what precipitated its domestication, because the edible portion of the wild variety is too small, and hard to obtain, to be eaten directly, as each kernel is enclosed in a very hard bivalve shell.
In 1939, George Beadle demonstrated that the kernels of teosinte are readily "popped" for human consumption, like modern popcorn. Some have argued it would have taken too many generations of selective breeding to produce large, compressed ears for efficient cultivation. However, studies of the hybrids readily made by intercrossing teosinte and modern maize suggest this objection is not well founded.
SPREADING TO THE NORTH
Around 4,500 ago, maize began to spread to the north; it was first cultivated in what is now the United States at several sites in New Mexico and Arizona, about 4,100 ago.
During the first millennium AD, maize cultivation spread more widely in the areas north. In particular, the large-scale adoption of maize agriculture and consumption in eastern North America took place about A.D. 900. Native Americans cleared large forest and grassland areas for the new crop.
In 2005, research by the USDA Forest Service suggested that the rise in maize cultivation 500 to 1,000 years ago in what is now the southeastern United States corresponded with a decline of freshwater mussels, which are very sensitive to environmental changes.
CULTIVATION
PLANTING
Because it is cold-intolerant, in the temperate zones maize must be planted in the spring. Its root system is generally shallow, so the plant is dependent on soil moisture. As a plant that uses C4 carbon fixation, maize is a considerably more water-efficient crop than plants that use C3 carbon fixation such as alfalfa and soybeans. Maize is most sensitive to drought at the time of silk emergence, when the flowers are ready for pollination. In the United States, a good harvest was traditionally predicted if the maize was "knee-high by the Fourth of July", although modern hybrids generally exceed this growth rate. Maize used for silage is harvested while the plant is green and the fruit immature. Sweet corn is harvested in the "milk stage", after pollination but before starch has formed, between late summer and early to mid-autumn. Field maize is left in the field until very late in the autumn to thoroughly dry the grain, and may, in fact, sometimes not be harvested until winter or even early spring. The importance of sufficient soil moisture is shown in many parts of Africa, where periodic drought regularly causes maize crop failure and consequent famine. Although it is grown mainly in wet, hot climates, it has been said to thrive in cold, hot, dry or wet conditions, meaning that it is an extremely versatile crop.
Maize was planted by the Native Americans in hills, in a complex system known to some as the Three Sisters. Maize provided support for beans, and the beans provided nitrogen derived from nitrogen-fixing rhizobia bacteria which live on the roots of beans and other legumes; and squashes provided ground cover to stop weeds and inhibit evaporation by providing shade over the soil. This method was replaced by single species hill planting where each hill 60–120 cm (2 ft 0 in–3 ft 11 in) apart was planted with three or four seeds, a method still used by home gardeners. A later technique was "checked maize", where hills were placed
1 m (40 in) apart in each direction, allowing cultivators to run through the field in two directions. In more arid lands, this was altered and seeds were planted in the bottom of 10–12 cm (4–4+1⁄2 in) deep furrows to collect water. Modern technique plants maize in rows which allows for cultivation while the plant is young, although the hill technique is still used in the maize fields of some Native American reservations. When maize is planted in rows, it also allows for planting of other crops between these rows to make more efficient use of land space.
In most regions today, maize grown in residential gardens is still often planted manually with a hoe, whereas maize grown commercially is no longer planted manually but rather is planted with a planter. In North America, fields are often planted in a two-crop rotation with a nitrogen-fixing crop, often alfalfa in cooler climates and soybeans in regions with longer summers. Sometimes a third crop, winter wheat, is added to the rotation.
Many of the maize varieties grown in the United States and Canada are hybrids. Often the varieties have been genetically modified to tolerate glyphosate or to provide protection against natural pests. Glyphosate is an herbicide which kills all plants except those with genetic tolerance. This genetic tolerance is very rarely found in nature.
In the midwestern United States, low-till or no-till farming techniques are usually used. In low-till, fields are covered once, maybe twice, with a tillage implement either ahead of crop planting or after the previous harvest. The fields are planted and fertilized. Weeds are controlled through the use of herbicides, and no cultivation tillage is done during the growing season. This technique reduces moisture evaporation from the soil, and thus provides more moisture for the crop. The technologies mentioned in the previous paragraph enable low-till and no-till farming. Weeds compete with the crop for moisture and nutrients, making them undesirable.
HARVESTING
Before the 20th century, all maize harvesting was by manual labour, by grazing, or by some combination of those. Whether the ears were hand-picked and the stover was grazed, or the whole plant was cut, gathered, and shocked, people and livestock did all the work. Between the 1890s and the 1970s, the technology of maize harvesting expanded greatly. Today, all such technologies, from entirely manual harvesting to entirely mechanized, are still in use to some degree, as appropriate to each farm's needs, although the thoroughly mechanized versions predominate, as they offer the lowest unit costs when scaled to large farm operations. For small farms, their unit cost can be too high, as their higher fixed cost cannot be amortized over as many units.[citation needed]
Before World War II, most maize in North America was harvested by hand. This involved a large number of workers and associated social events (husking or shucking bees). From the 1890s onward, some machinery became available to partially mechanize the processes, such as one- and two-row mechanical pickers (picking the ear, leaving the stover) and corn binders, which are reaper-binders designed specifically for maize (for example, Video on YouTube). The latter produce sheaves that can be shocked. By hand or mechanical picker, the entire ear is harvested, which then requires a separate operation of a maize sheller to remove the kernels from the ear. Whole ears of maize were often stored in corn cribs, and these whole ears are a sufficient form for some livestock feeding use. Today corn cribs with whole ears, and corn binders, are less common because most modern farms harvest the grain from the field with a combine and store it in bins. The combine with a corn head (with points and snap rolls instead of a reel) does not cut the stalk; it simply pulls the stalk down. The stalk continues downward and is crumpled into a mangled pile on the ground, where it usually is left to become organic matter for the soil. The ear of maize is too large to pass between slots in a plate as the snap rolls pull the stalk away, leaving only the ear and husk to enter the machinery. The combine separates the husk and the cob, keeping only the kernels.
When maize is a silage crop, the entire plant is usually chopped at once with a forage harvester (chopper) and ensiled in silos or polymer wrappers. Ensiling of sheaves cut by a corn binder was formerly common in some regions but has become uncommon. For storing grain in bins, the moisture of the grain must be sufficiently low to avoid spoiling. If the moisture content of the harvested grain is too high, grain dryers are used to reduce the moisture content by blowing heated air through the grain. This can require large amounts of energy in the form of combustible gases (propane or natural gas) and electricity to power the blowers.
PRODUCTION
Maize is widely cultivated throughout the world, and a greater weight of maize is produced each year than any other grain. In 2018, total world production was 1.15 billion tonnes, led by the United States with 34.2% of the total (table). China produced 22.4% of the global total.
UNITED STATES
In 2016, maize production was forecast to be over 380 million metric tons (15 billion bushels), an increase of 11% over 2014 American production. Based on conditions as of August 2016, the expected yield would be the highest ever for the United States. The area of harvested maize was forecast to be 35 million hectares (87 million acres), an increase of 7% over 2015. Maize is especially popular in Midwestern states such as Indiana, Iowa, and Illinois; in the latter, it was named the state's official grain in 2017.
STORAGE
Drying is vital to prevent or at least reduce mycotoxin contamination. Aspergillus and Fusarium spp. are the most common mycotoxin sources, but there are others. Altogether maize contaminants are so common, and this crop is so economically important, that maize mycotoxins are among the most important in agriculture in general.
USES
HUMAN FOOD
Maize and cornmeal (ground dried maize) constitute a staple food in many regions of the world. Maize is used to produce cornstarch, a common ingredient in home cooking and many industrialized food products. Maize starch can be hydrolyzed and enzymatically treated to produce syrups, particularly high fructose corn syrup, a sweetener; and also fermented and distilled to produce grain alcohol. Grain alcohol from maize is traditionally the source of Bourbon whiskey. Corn flour is used to make cornbread and other baked products.
In prehistoric times Mesoamerican women used a metate to process maize into ground cornmeal, allowing the preparation of foods that were more calorie dense than popcorn. After ceramic vessels were invented the Olmec people began to cook maize together with beans, improving the nutritional value of the staple meal. Although maize naturally contains niacin, an important nutrient, it was not bioavailable without the process of nixtamalization. The Maya used nixtamal meal to make varieties of porridges and tamales. The process was later used in the cuisine of the American South to prepare corn for grits and hominy.
Maize is a staple of Mexican cuisine. Masa (cornmeal treated with limewater) is the main ingredient for tortillas, atole and many other dishes of Central American food. It is the main ingredient of corn tortilla, tamales, pozole, atole and all the dishes based on them, like tacos, quesadillas, chilaquiles, enchiladas, tostadas and many more. In Mexico the fungus of maize, known as huitlacoche, is considered a delicacy.
Coarse maize meal is made into a thick porridge in many cultures: from the polenta of Italy, the angu of Brazil, the mămăligă of Romania, to cornmeal mush in the US (or hominy grits in the South) or the food called mieliepap in South Africa and sadza, nshima, ugali and other names in other parts of Africa. Introduced into Africa by the Portuguese in the 16th century, maize has become Africa's most important staple food crop. These are commonly eaten in the Southeastern United States, foods handed down from Native Americans, who called the dish sagamite.
Maize can also be harvested and consumed in the unripe state, when the kernels are fully grown but still soft. Unripe maize must usually be cooked to become palatable; this may be done by simply boiling or roasting the whole ears and eating the kernels right off the cob. Sweet corn, a genetic variety that is high in sugars and low in starch, is usually consumed in the unripe state. Such corn on the cob is a common dish in the United States, Canada, United Kingdom, Cyprus, some parts of South America, and the Balkans, but virtually unheard of in some European countries. Corn on the cob was hawked on the streets of early 19th-century New York City by poor, barefoot "Hot Corn Girls", who were thus the precursors of hot dog carts, churro wagons, and fruit stands seen on the streets of big cities today.
Within the United States, the usage of maize for human consumption constitutes only around 1/40th of the amount grown in the country. In the United States and Canada, maize is mostly grown to feed livestock, as forage, silage (made by fermentation of chopped green cornstalks), or grain. Maize meal is also a significant ingredient of some commercial animal food products.
NUTRITIONAL VALUE
Raw, yellow, sweet maize kernels are composed of 76% water, 19% carbohydrates, 3% protein, and 1% fat (table). In a 100-gram serving, maize kernels provide 86 calories and are a good source (10–19% of the Daily Value) of the B vitamins, thiamin, niacin (but see Pellagra warning below), pantothenic acid (B5) and folate (right table for raw, uncooked kernels, USDA Nutrient Database). In moderate amounts, they also supply dietary fiber and the essential minerals, magnesium and phosphorus whereas other nutrients are in low amounts (table).
Maize has suboptimal amounts of the essential amino acids tryptophan and lysine, which accounts for its lower status as a protein source. However, the proteins of beans and legumes complement those of maize.
FEED AND FODDER FOR LIVESTOCK
Maize is a major source of both grain feed and fodder for livestock. It is fed to the livestock in various ways. When it is used as a grain crop, the dried kernels are used as feed. They are often kept on the cob for storage in a corn crib, or they may be shelled off for storage in a grain bin. The farm that consumes the feed may produce it, purchase it on the market, or some of both. When the grain is used for feed, the rest of the plant (the corn stover) can be used later as fodder, bedding (litter), or soil amendment. When the whole maize plant (grain plus stalks and leaves) is used for fodder, it is usually chopped all at once and ensilaged, as digestibility and palatability are higher in the ensilaged form than in the dried form. Maize silage is one of the most valuable forages for ruminants. Before the advent of widespread ensilaging, it was traditional to gather the corn into shocks after harvesting, where it dried further. With or without a subsequent move to the cover of a barn, it was then stored for weeks to several months until fed to the livestock. Today ensilaging can occur not only in siloes but also in silage wrappers. However, in the tropics, maize can be harvested year-round and fed as green forage to the animals.
CHEMICALS
Starch from maize can also be made into plastics, fabrics, adhesives, and many other chemical products.
The corn steep liquor, a plentiful watery byproduct of maize wet milling process, is widely used in the biochemical industry and research as a culture medium to grow many kinds of microorganisms.
Chrysanthemin is found in purple corn and is used as a food coloring.
BIO-FUEL
"Feed maize" is being used increasingly for heating; specialized corn stoves (similar to wood stoves) are available and use either feed maize or wood pellets to generate heat. Maize cobs are also used as a biomass fuel source. Maize is relatively cheap and home-heating furnaces have been developed which use maize kernels as a fuel. They feature a large hopper that feeds the uniformly sized maize kernels (or wood pellets or cherry pits) into the fire.[citation needed]
Maize is increasingly used as a feedstock for the production of ethanol fuel. When considering where to construct an ethanol plant, one of the site selection criteria is to ensure there is locally available feedstock. Ethanol is mixed with gasoline to decrease the amount of pollutants emitted when used to fuel motor vehicles. High fuel prices in mid-2007 led to higher demand for ethanol, which in turn led to higher prices paid to farmers for maize. This led to the 2007 harvest being one of the most profitable maize crops in modern history for farmers. Because of the relationship between fuel and maize, prices paid for the crop now tend to track the price of oil.
The price of food is affected to a certain degree by the use of maize for biofuel production. The cost of transportation, production, and marketing are a large portion (80%) of the price of food in the United States. Higher energy costs affect these costs, especially transportation. The increase in food prices the consumer has been seeing is mainly due to the higher energy cost. The effect of biofuel production on other food crop prices is indirect. Use of maize for biofuel production increases the demand, and therefore price of maize. This, in turn, results in farm acreage being diverted from other food crops to maize production. This reduces the supply of the other food crops and increases their prices.
Maize is widely used in Germany as a feedstock for biogas plants. Here the maize is harvested, shredded then placed in silage clamps from which it is fed into the biogas plants. This process makes use of the whole plant rather than simply using the kernels as in the production of fuel ethanol.
A biomass gasification power plant in Strem near Güssing, Burgenland, Austria, began in 2005. Research is being done to make diesel out of the biogas by the Fischer Tropsch method.
Increasingly, ethanol is being used at low concentrations (10% or less) as an additive in gasoline (gasohol) for motor fuels to increase the octane rating, lower pollutants, and reduce petroleum use (what is nowadays also known as "biofuels" and has been generating an intense debate regarding the human beings' necessity of new sources of energy, on the one hand, and the need to maintain, in regions such as Latin America, the food habits and culture which has been the essence of civilizations such as the one originated in Mesoamerica; the entry, January 2008, of maize among the commercial agreements of NAFTA has increased this debate, considering the bad labor conditions of workers in the fields, and mainly the fact that NAFTA "opened the doors to the import of maize from the United States, where the farmers who grow it receive multimillion-dollar subsidies and other government supports. ... According to OXFAM UK, after NAFTA went into effect, the price of maize in Mexico fell 70% between 1994 and 2001. The number of farm jobs dropped as well: from 8.1 million in 1993 to 6.8 million in 2002. Many of those who found themselves without work were small-scale maize growers."). However, introduction in the northern latitudes of the US of tropical maize for biofuels, and not for human or animal consumption, may potentially alleviate this.
COMMODITY
Maize is bought and sold by investors and price speculators as a tradable commodity using corn futures contracts. These "futures" are traded on the Chicago Board of Trade (CBOT) under ticker symbol C. They are delivered every year in March, May, July, September, and December.
ORNAMENTAL AND OTHER USES
Some forms of the plant are occasionally grown for ornamental use in the garden. For this purpose, variegated and colored leaf forms as well as those with colorful ears are used.
Corncobs can be hollowed out and treated to make inexpensive smoking pipes, first manufactured in the United States in 1869.
An unusual use for maize is to create a "corn maze" (or "maize maze") as a tourist attraction. The idea of a maize maze was introduced by the American Maze Company who created a maze in Pennsylvania in 1993. Traditional mazes are most commonly grown using yew hedges, but these take several years to mature. The rapid growth of a field of maize allows a maze to be laid out using GPS at the start of a growing season and for the maize to grow tall enough to obstruct a visitor's line of sight by the start of the summer. In Canada and the US, these are popular in many farming communities.
Maize kernels can be used in place of sand in a sandboxlike enclosure for children's play.
Stigmas from female maize flowers, popularly called corn silk, are sold as herbal supplements.
Maize is used as a fish bait, called "dough balls". It is particularly popular in Europe for coarse fishing.
Additionally, feed corn is sometimes used by hunters to bait animals such as deer or wild hogs.
UNITED STATES USAGE BREAKDOWN
The breakdown of usage of the 12.1-billion-bushel (307-million-tonne) 2008 US maize crop was as follows, according to the World Agricultural Supply and Demand Estimates Report by the USDA.In the US since 2009/2010, maize feedstock use for ethanol production has somewhat exceeded direct use for livestock feed; maize use for fuel ethanol was 5,130 million bushels (130 million tonnes) in the 2013/2014 marketing year.A fraction of the maize feedstock dry matter used for ethanol production is usefully recovered as DDGS (dried distillers grains with solubles). In the 2010/2011 marketing year, about 29.1 million tonnes of DDGS were fed to US livestock and poultry. Because starch utilization in fermentation for ethanol production leaves other grain constituents more concentrated in the residue, the feed value per kg of DDGS, with regard to ruminant-metabolizable energy and protein, exceeds that of the grain. Feed value for monogastric animals, such as swine and poultry, is somewhat lower than for ruminants.
HAZARDS
PELLAGRA
When maize was first introduced into farming systems other than those used by traditional native-American peoples, it was generally welcomed with enthusiasm for its productivity. However, a widespread problem of malnutrition soon arose wherever maize was introduced as a staple food. This was a mystery, since these types of malnutrition were not normally seen among the indigenous Americans, for whom maize was the principal staple food.
It was eventually discovered that the indigenous Americans had learned to soak maize in alkali — water (the process now known as nixtamalization) — made with ashes and lime (calcium oxide) since at least 1200–1500 BC by Mesoamericans. They did this to liberate the corn hulls, but (unbeknownst to natives or colonists) it coincidentally liberates the B-vitamin niacin, the lack of which was the underlying cause of the condition known as pellagra.
Maize was introduced into the diet of non-indigenous Americans without the necessary cultural knowledge acquired over thousands of years in the Americas. In the late 19th century, pellagra reached epidemic proportions in parts of the southern US, as medical researchers debated two theories for its origin: the deficiency theory (which was eventually shown to be true) said that pellagra was due to a deficiency of some nutrient, and the germ theory said that pellagra was caused by a germ transmitted by stable flies. A third theory, promoted by the eugenicist Charles Davenport, held that people only contracted pellagra if they were susceptible to it due to certain "constitutional, inheritable" traits of the affected individual.
Once alkali processing and dietary variety were understood and applied, pellagra disappeared in the developed world. The development of high lysine maize and the promotion of a more balanced diet have also contributed to its demise. Pellagra still exists today in food-poor areas and refugee camps where people survive on donated maize.
ALLERGY
Maize contains lipid transfer protein, an indigestible protein that survives cooking. This protein has been linked to a rare and understudied allergy to maize in humans. The allergic reaction can cause skin rash, swelling or itching of mucous membranes, diarrhea, vomiting, asthma and, in severe cases, anaphylaxis. It is unclear how common this allergy is in the general population.
MYCOTOXINS
Fungicide application does not reduce fungal growth or mycotoxin dramatically, although it can be a part of a successful reduction strategy. Among the most common toxins are those produced by Aspergillus and Fusarium spp. The most common toxins are aflatoxins, fumonisins, zearalenone, and ochratoxin A. Bt maize discourages insect vectors and by so doing it dramatically reduces concentrations of fumonisins, significantly reduces aflatoxins, but only mildly reduces others.
ART
Maize has been an essential crop in the Andes since the pre-Columbian era. The Moche culture from Northern Peru made ceramics from earth, water, and fire. This pottery was a sacred substance, formed in significant shapes and used to represent important themes. Maize was represented anthropomorphically as well as naturally.
In the United States, maize ears along with tobacco leaves are carved into the capitals of columns in the United States Capitol building. Maize itself is sometimes used for temporary architectural detailing when the intent is to celebrate the fall season, local agricultural productivity and culture. Bundles of dried maize stalks are often displayed along with pumpkins, gourds and straw in autumnal displays outside homes and businesses. A well-known example of architectural use is the Corn Palace in Mitchell, South Dakota, which uses cobs and ears of colored maize to implement a mural design that is recycled annually. Another well-known example is the Field of Corn sculpture in Dublin, Ohio, where hundreds of concrete ears of corn stand in a grassy field.
A maize stalk with two ripe ears is depicted on the reverse of the Croatian 1 lipa coin, minted since 1993.
WIKIPEDIA
The bar-headed goose (Anser indicus) is a goose that breeds in Central Asia in colonies of thousands near mountain lakes and winters in South Asia, as far south as peninsular India. It lays three to eight eggs at a time in a ground nest. It is known for the extreme altitudes it reaches when migrating across the Himalayas.
Taxonomy
The grey goose genus Anser has no other member indigenous to the Indian region, nor any at all to the Ethiopian, Australian, or Neotropical regions. Ludwig Reichenbach placed the bar-headed goose in the monotypic genus Eulabeia in 1852, though John Boyd's taxonomy treats both Eulabeia and the genus Chen as subgenera of Anser.
Description
The bird is pale grey and is easily distinguished from any of the other grey geese of the genus Anser by the black bars on its head. It is also much paler than the other geese in this genus. In flight, its call is a typical goose honking. A mid-sized goose, it measures 71–76 cm (28–30 in) in total length and weighs 1.87–3.2 kg (4.1–7.1 lb).
Ecology
The summer habitat is high-altitude lakes where the bird grazes on short grass. The species has been reported as migrating south from Tibet, Kazakhstan, Mongolia and Russia before crossing the Himalayas. The bird has come to the attention of medical science in recent years as having been an early victim of the H5N1 virus, HPAI (highly pathogenic avian influenza), at Qinghai. It suffers predation from crows, foxes, ravens, sea eagles, gulls and others. The total population may, however, be increasing, but it is complex to assess population trends, as this species occurs over more than 2,500,000 km2 (970,000 sq mi).
The bar-headed goose is one of the world's highest-flying birds, having been heard flying across Mount Makalu – the fifth highest mountain on earth at 8,481 m (27,825 ft) – and apparently seen over Mount Everest – 8,848 m (29,029 ft) – although this is a second-hand report with no verification. This demanding migration has long puzzled physiologists and naturalists: "there must be a good explanation for why the birds fly to the extreme altitudes... particularly since there are passes through the Himalaya at lower altitudes, and which are used by other migrating bird species." In fact, bar-headed geese had for a long time not been directly tracked (using GPS or satellite logging technology) flying higher than 6,540 metres (21,460 ft), and it is now believed that they do take the high passes through the mountains. The challenging northward migration from lowland India to breed in the summer on the Tibetan Plateau is undertaken in stages, with the flight across the Himalaya (from sea-level) being undertaken non-stop in as little as seven hours. Surprisingly, despite predictable tail winds that blow up the Himalayas (in the same direction of travel as the geese), bar-headed geese spurn these winds, waiting for them to die down overnight, when they then undertake the greatest rates of climbing flight ever recorded for a bird, and sustain these climbs rates for hours on end, according to research published in 2011.
The 2011 study found the geese peaking at an altitude of around 6,400 m (21,000 ft). In a 2012 study that tagged 91 geese and tracked their migration routes, it was determined that the geese spent 95% of their time below 5,784 m (18,976 ft), choosing to take a longer route through the Himalayas in order to utilize lower-altitude valleys and passes. Only 10 of the tagged geese were ever recorded above this altitude, and only one exceeded 6,500 m (21,300 ft), reaching 7,290 m (23,920 ft). All but one of these high-altitude flights were recorded at night, which along with the early morning, is the most common time of day for geese migration. The colder denser air during these times may be equivalent to an altitude hundreds of meters lower. It is suspected by the authors of these two studies that tales of the geese flying at 8,000 m (26,000 ft) are apocryphal.[8] Bar headed geese have been observed flying at 7,000 metres (23,000 ft).
The bar-headed goose migrates over the Himalayas to spend the winter in parts of South Asia (from Assam to as far south as Tamil Nadu. The modern winter habitat of the species is cultivated fields, where it feeds on barley, rice and wheat, and may damage crops. Birds from Kyrgyzstan have been seen to stopover in western Tibet and southern Tajikistan for 20 to 30 days before migrating farther south. Some birds may show high wintering site fidelity.
They nest mainly on the Tibetan Plateau. Intraspecific brood parasitism is noticed with lower rank females attempting to lay their eggs in the nests of higher ranking females.
The bar-headed goose is often kept in captivity, as it is considered beautiful and breeds readily. Recorded sightings in Great Britain are frequent, and almost certainly relate to escapes. However, the species has bred on several occasions in recent years, and around five pairs were recorded in 2002, the most recent available report of the Rare Birds Breeding Panel. It is possible that, owing to a combination of frequent migration, accidental escapes and deliberate introduction, the species is becoming gradually more established in Great Britain.
The bar-headed goose has escaped or been deliberately released in Florida, U.S., but there is no evidence that the population is breeding and it may only persist due to continuing escapes or releases.
Physiology and morphology
The main physiological challenge of bar-headed geese is extracting oxygen from hypoxic air and transporting it to aerobic muscle fibres in order to sustain flight at high altitudes. Flight is very metabolically costly at high-altitudes because birds need to flap harder in thin air to generate lift. Studies have found that bar-headed geese breathe more deeply and efficiently under low-oxygen conditions, which serves to increase oxygen uptake from the environment. The haemoglobin of their blood has a higher affinity for oxygen than that of low-altitude geese, which has been attributed to a single amino acid point mutation. This mutation causes a conformational shift in the haemoglobin molecule from the low-oxygen to the high-oxygen affinity form. The left-ventricle of the heart, which is responsible for pumping oxygenated blood to the body via systemic circulation, has significantly more capillaries in bar-headed geese than in lowland birds, maintaining oxygenation of cardiac muscle cells and thereby cardiac output. Compared to lowland birds, mitochondria (the main site of oxygen consumption) in the flight muscle of bar-headed geese are significantly closer to the sarcolemma, decreasing the intracellular diffusion distance of oxygen from the capillaries to the mitochondria.
Bar-headed geese have a slightly larger wing area for their weight than other geese, which is believed to help them fly at high altitudes. While this decreases the power output required for flight in thin air, birds at high altitude still need to flap harder than lowland birds.
Cultural depiction
The bar-headed goose has been suggested as being the model for the Hamsa of Indian mythology. Another interpretation suggests that the bar-headed goose is likely to be the Kadamb in ancient and medieval Sanskrit literature, whereas Hamsa generally refers to the swan.
Dutch nature -
Honey fungus is a "white rot" fungus, which is a pathogenic organism that affects trees, shrubs, woody climbers and, rarely, woody herbaceous perennial plants. Honey fungus can grow on living, decaying, and dead plant material.
Honey fungus spreads from living trees, dead and live roots and stumps by means of reddish-brown to black rhizomorphs (root-like structures) at the rate of approximately 1 m a year, but infection by root contact is possible. Infection by spores is rare. Rhizomorphs grow close to the soil surface (in the top 20 cm) and invade new roots, or the root collar (where the roots meet the stem) of plants. An infected tree will die once the fungus has it, or when significant root damage has occurred. This can happen rapidly, or may take several years. Infected plants will deteriorate, although may exhibit prolific flower or fruit production shortly before death.
Naturgetreue Abblidungen und Beschreibungen der essbaren, schädlichen und verdächtigen Schwämme /
Prag :In Commission in der J. G. Calve'schen Buchhandlung,1831-1846.
The pintail or northern pintail (Anas acuta) is a duck species with wide geographic distribution that breeds in the northern areas of Europe and across the Palearctic and North America. It is migratory and winters south of its breeding range to the equator. Unusually for a bird with such a large range, it has no geographical subspecies if the possibly conspecific duck Eaton's pintail is considered to be a separate species.
This is a large duck, and the male's long central tail feathers give rise to the species' English and scientific names. Both sexes have blue-grey bills and grey legs and feet. The drake is more striking, having a thin white stripe running from the back of its chocolate-coloured head down its neck to its mostly white undercarriage. The drake also has attractive grey, brown, and black patterning on its back and sides. The hen's plumage is more subtle and subdued, with drab brown feathers similar to those of other female dabbling ducks. Hens make a coarse quack and the drakes a flute-like whistle.
The northern pintail is a bird of open wetlands which nests on the ground, often some distance from water. It feeds by dabbling for plant food and adds small invertebrates to its diet during the nesting season. It is highly gregarious when not breeding, forming large mixed flocks with other species of duck. This duck's population is affected by predators, parasites and avian diseases. Human activities, such as agriculture, hunting and fishing, have also had a significant impact on numbers. Nevertheless, owing to the huge range and large population of this species, it is not threatened globally.
Taxonomy
This species was first described by Carl Linnaeus in his landmark 1758 10th edition of Systema Naturae as Anas acuta. The scientific name comes from two Latin words: anas, meaning "duck", and acuta, which comes from the verb acuere, "to sharpen"; the species term like the English name, refers to the pointed tail of the male in breeding plumage. Within the large dabbling duck genus Anas, the northern pintail's closest relatives are other pintails, such as the yellow-billed pintail (A. georgica) and Eaton's pintail (A. eatoni). The pintails are sometimes separated in the genus Dafila (described by Stephens, 1824), an arrangement supported by morphological, molecular and behavioural data. The famous British ornithologist Sir Peter Scott gave this name to his daughter, the artist Dafila Scott.
Eaton's pintail has two subspecies, A. e. eatoni (the Kerguelen pintail) of Kerguelen Islands, and A. e. drygalskyi (the Crozet pintail) of Crozet Islands, and was formerly considered conspecific with the Northern Hemisphere's northern pintail. Sexual dimorphism is much less marked in the southern pintails, with the male's breeding appearance being similar to the female plumage. Unusually for a species with such a large range, northern pintail has no geographical subspecies if Eaton's pintail is treated as a separate species.
A claimed extinct subspecies from Manra Island, Tristram's pintail, A. a. modesta, appears to be indistinguishable from the nominate form. The three syntype specimens of Dafila modesta Tristram (Proceedings of the Zoological Society of London, 1886, p.79. pl. VII), the extinct subspecies, are held in the vertebrate zoology collections of National Museums Liverpool at World Museum, with accession numbers NML-VZ T11792 (male immature), NML-VZ T11795 (female adult) and NML-VZ T11797 (female adult). The specimens were collected by J. V. Arundel in Sydney Island (Manra Island), Phoenix Islands in 1885 and came to the Liverpool national collection via Canon Henry Baker Tristram's collection which was purchased in 1896.
Description
The northern pintail is a fairly large duck with a wing chord of 23.6–28.2 cm (9.3–11.1 in) and wingspan of 80–95 cm (31–37 in). The male is 59–76 cm (23–30 in) in length and weighs 450–1,360 g (0.99–3.00 lb), and therefore is considerably larger than the female, which is 51–64 cm (20–25 in) long and weighs 454–1,135 g (1.001–2.502 lb). The northern pintail broadly overlaps in size with the similarly widespread mallard, but is more slender, elongated and gracile, with a relatively longer neck and (in males) a longer tail. The unmistakable breeding plumaged male has a chocolate-brown head and white breast with a white stripe extending up the side of the neck. Its upperparts and sides are grey, but elongated grey feathers with black central stripes are draped across the back from the shoulder area. The vent area is yellow, contrasting with the black underside of the tail, which has the central feathers elongated to as much as 10 cm (3.9 in). The bill is bluish and the legs are blue-grey.
The adult female is mainly scalloped and mottled in light brown with a more uniformly grey-brown head, and its pointed tail is shorter than the male's; it is still easily identified by its shape, long neck, and long grey bill. In non-breeding (eclipse) plumage, the drake pintail looks similar to the female, but retains the male upperwing pattern and long grey shoulder feathers. Juvenile birds resemble the female, but are less neatly scalloped and have a duller brown speculum with a narrower trailing edge.
The pintail walks well on land, and swims well. In water, the swimming posture is forward leaning, with the base of the neck almost flush with the water. It has a very fast flight, with its wings slightly swept-back, rather than straight out from the body like other ducks. In flight, the male shows a black speculum bordered white at the rear and pale rufous at the front, whereas the female's speculum is dark brown bordered with white, narrowly at the front edge but very prominently at the rear, being visible at a distance of 1,600 m (0.99 mi).
The male's call is a soft proop-proop whistle, similar to that of the common teal, whereas the female has a mallard-like descending quack, and a low croak when flushed.
This dabbling duck breeds across northern areas of the Palearctic south to about Poland and Mongolia, and in Canada, Alaska and the Midwestern United States. It mainly winters south of its breeding range, reaching almost to the equator in Panama, northern sub-Saharan Africa and tropical South Asia. Small numbers migrate to Pacific islands, particularly Hawaii, where a few hundred birds winter on the main islands in shallow wetlands and flooded agricultural habitats. Transoceanic journeys also occur: a bird that was caught and ringed in Labrador, Canada, was shot by a hunter in England nine days later, and Japanese-ringed birds have been recovered from six US states east to Utah and Mississippi. In parts of the range, such as Great Britain and the northwestern United States, the pintail may be present all year.
The northern pintail's breeding habitat is open unwooded wetlands, such as wet grassland, lakesides or tundra. In winter, it will utilise a wider range of open habitats, such as sheltered estuaries, brackish marshes and coastal lagoons. It is highly gregarious outside the breeding season and forms very large mixed flocks with other ducks.
Behaviour
Both sexes reach sexual maturity at one year of age. The male mates with the female by swimming close to her with his head lowered and tail raised, continually whistling. If there is a group of males, they will chase the female in flight until only one drake is left. The female prepares for copulation, which takes place in the water, by lowering her body; the male then bobs his head up and down and mounts the female, taking the feathers on the back of her head in his mouth. After mating, he raises his head and back and whistles.
Among the earliest species to breed in the spring, northern pintails typically form pairs during migration, or even while still on wintering grounds. Breeding takes place between April and June, with the nest being constructed on the ground and hidden amongst vegetation in a dry location, often some distance from water. It is a shallow scrape on the ground lined with plant material and down. The female lays seven to nine cream-coloured eggs at the rate of one per day; the eggs are 55 mm × 38 mm (2.2 in × 1.5 in) in size and weigh 45 g (1.6 oz), of which 7% is shell. If predators destroy the first clutch, the female can produce a replacement clutch as late as the end of July. The hen alone incubates the eggs for 22 to 24 days before they hatch. The precocial downy chicks are then led by the female to the nearest body of water, where they feed on dead insects on the water surface. The chicks fledge in 46 to 47 days after hatching, but stay with the female until she has completed moulting.
Around three-quarters of chicks live long enough to fledge, but not more than half of those survive long enough to reproduce. The maximum recorded age is 27 years and 5 months for a Dutch bird.
Feeding
The pintail feeds by dabbling and upending in shallow water for plant food mainly in the evening or at night, and therefore spends much of the day resting. Its long neck enables it to take food items from the bottom of water bodies up to 30 cm (12 in) deep, which are beyond the reach of other dabbling ducks like the mallard.
The winter diet is mainly plant material including seeds and rhizomes of aquatic plants, but the pintail sometimes feeds on roots, grain and other seeds in fields, though less frequently than other Anas ducks. During the nesting season, this bird eats mainly invertebrate animals, including aquatic insects, molluscs and crustaceans.
Health
Pintail nests and chicks are vulnerable to predation by mammals, such as foxes and badgers, and birds like gulls, crows and magpies. The adults can take flight to escape terrestrial predators, but nesting females in particular may be surprised by large carnivores such as bobcats. Large birds of prey, such as northern goshawks, will take ducks from the ground, and some falcons, including the gyrfalcon, have the speed and power to catch flying birds.
It is susceptible to a range of parasites including Cryptosporidium, Giardia, tapeworms, blood parasites and external feather lice, and is also affected by other avian diseases. It is often the dominant species in major mortality events from avian botulism and avian cholera, and can also contract avian influenza, the H5N1 strain of which is highly pathogenic and occasionally infects humans.
The northern pintail is a popular species for game shooting because of its speed, agility, and excellent eating qualities, and is hunted across its range. Although one of the world's most numerous ducks, the combination of hunting with other factors has led to population declines, and local restrictions on hunting have been introduced at times to help conserve numbers.
This species' preferred habitat of shallow water is naturally susceptible to problems such as drought or the encroachment of vegetation, but this duck's habitat might be increasingly threatened by climate change. Populations are also affected by the conversion of wetlands and grassland to arable crops, depriving the duck of feeding and nesting areas. Spring planting means that many nests of this early breeding duck are destroyed by farming activities, and a Canadian study showed that more than half of the surveyed nests were destroyed by agricultural work such as ploughing and harrowing.
Hunting with lead shot, along with the use of lead sinkers in angling, has been identified as a major cause of lead poisoning in waterfowl, which often feed off the bottom of lakes and wetlands where the shot collects. A Spanish study showed that northern pintail and common pochard were the species with the highest levels of lead shot ingestion, higher than in northern countries of the western Palearctic flyway, where lead shot has been banned. In the United States, Canada, and many western European countries, all shot used for waterfowl must now be non-toxic, and therefore may not contain any lead.
Status
The northern pintail has a large range, estimated at 41,900,000 km2 (16,200,000 sq mi), and a population estimated at 4.8–4.9 million individuals. The IUCN has categorised the northern pintail as not being threatened globally, however it is endangered in Europe.
In the Palaearctic, breeding populations are declining in much of the range, including its stronghold in Russia. In other regions, populations are stable or fluctuating.
Pintails in North America at least have been badly affected by avian diseases, with the breeding population falling from more than 10 million in 1957 to 3.5 million by 1964. Although the species has recovered from that low point, the breeding population in 1999 was 30% below the long-term average, despite years of major efforts focused on restoring the species. In 1997, an estimated 1.5 million water birds, the majority being northern pintails, died from avian botulism during two outbreaks in Canada and Utah.
The northern pintail is one of the species to which the Agreement on the Conservation of African-Eurasian Migratory Waterbirds (AEWA) applies, but it has no special status under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES), which regulates international trade in specimens of wild animals and plants.
World leader, scientist, medical scientist, virologist, pharmacist, Professor Fangruida (F.D Smith) on the world epidemic and the nemesis and prevention of new coronaviruses and mutant viruses (Jacques Lucy) 2021v1.5)
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The Nemesis and Killer of New Coronavirus and Mutated Viruses-Joint Development of Vaccines and Drugs (Fangruida) July 2021
*The particularity of new coronaviruses and mutant viruses*The broad spectrum, high efficiency, redundancy, and safety of the new coronavirus vaccine design and development , Redundancy and safety
*New coronavirus drug chemical structure modification*Computer-aided design and drug screening. *"Antiviral biological missile", "New Coronavirus Anti-epidemic Tablets", "Composite Antiviral Oral Liquid", "New Coronavirus Long-acting Oral Tablets", "New Coronavirus Inhibitors" (injection)
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(World leader, scientist, medical scientist, biologist, virologist, pharmacist, FD Smith) "The Nemesis and Killer of New Coronavirus and Mutated Viruses-The Joint Development of Vaccines and Drugs" is an important scientific research document. Now it has been revised and re-published by the original author several times. The compilation is published and published according to the original manuscript to meet the needs of readers and netizens all over the world. At the same time, it is also of great benefit to the vast number of medical clinical drug researchers and various experts and scholars. We hope that it will be corrected in the reprint.------Compiled by Jacques Lucy in Geneva, August 2021
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According to Worldometer's real-time statistics, as of about 6:30 on July 23, there were a total of 193,323,815 confirmed cases of new coronary pneumonia worldwide, and a total of 4,150,213 deaths. There were 570,902 new confirmed cases and 8,766 new deaths worldwide in a single day. Data shows that the United States, Brazil, the United Kingdom, India, and Indonesia are the five countries with the largest number of new confirmed cases, and Indonesia, Brazil, Russia, South Africa, and India are the five countries with the largest number of new deaths.
The new coronavirus and delta mutant strains have been particularly serious in the recent past. Many countries and places have revived, and the number of cases has not decreased, but has increased.
, It is worthy of vigilance. Although many countries have strengthened vaccine prevention and control and other prevention and control measures, there are still many shortcomings and deficiencies in virus suppression and prevention. The new coronavirus and various mutant strains have a certain degree of antagonism to traditional drugs and most vaccines. Although most vaccines have great anti-epidemic properties and have important and irreplaceable effects and protection for prevention and treatment, it is impossible to completely prevent the spread and infection of viruses. The spread of the new crown virus pneumonia has been delayed for nearly two years. There are hundreds of millions of people infected worldwide, millions of deaths, and the time is long, the spread is widespread, and billions of people around the world are among them. The harm of the virus is quite terrible. This is well known. of. More urgent
What is more serious is that the virus and mutant strains have not completely retreated, especially many people are still infected and infected after being injected with various vaccines. The effectiveness of the vaccine and the resistance of the mutant virus are worthy of medical scientists, virologists, pharmacologists Zoologists and others seriously think and analyze. The current epidemic situation in European and American countries, China, Brazil, India, the United States, Russia and other countries has greatly improved from last year. However, relevant figures show that the global epidemic situation has not completely improved, and some countries and regions are still very serious. In particular, after extensive use of various vaccines, cases still occur, and in some places they are still very serious, which deserves a high degree of vigilance. Prevention and control measures are very important. In addition, vaccines and various anti-epidemic drugs are the first and necessary choices, and other methods are irreplaceable. It is particularly important to develop and develop comprehensive drugs, antiviral drugs, immune drugs, and genetic drugs. Research experiments on new coronaviruses and mutant viruses require more rigorous and in-depth data analysis, pathological pathogenic tissues, cell genes, molecular chemistry, quantum chemistry, etc., as well as vaccine molecular chemistry, quantum physics, quantum biology, cytological histology, medicinal chemistry, and drugs And the vaccine’s symptomatic, effectiveness, safety, long-term effectiveness, etc., of course, including tens of thousands of clinical cases and deaths and other first-hand information and evidence. The task of RNA (ribonucleic acid) in the human body is to use the information of our genetic material DNA to produce protein. It accomplishes this task in the ribosome, the protein-producing area of the cell. The ribosome is the place where protein biosynthesis occurs.
Medicine takes advantage of this: In vaccination, artificially produced mRNA provides ribosomes with instructions for constructing pathogen antigens to fight against—for example, the spike protein of coronavirus.
Traditional live vaccines or inactivated vaccines contain antigens that cause the immune system to react. The mRNA vaccine is produced in the cell
(1) The specificity of new coronaviruses and mutant viruses, etc., virology and quantum chemistry of mutant viruses, quantum physics, quantum microbiology
(2) New crown vaccine design, molecular biology and chemical structure, etc.
(3) The generality and particularity of the development of new coronavirus drugs
(4) Various drug design for new coronavirus pneumonia, medicinal chemistry, pharmacology, etc., cells, proteins, DNA, enzyme chemistry, pharmaceutical quantum chemistry, pharmaceutical quantum physics, human biochemistry, human biophysics, etc.
(5) The evolution and mutation characteristics of the new coronavirus and various mutant viruses, the long-term nature, repeatability, drug resistance, and epidemic resistance of the virus, etc.
(6) New coronavirus pneumonia and the infectious transmission of various new coronaviruses and their particularities
(7) The invisible transmission of new coronavirus pneumonia and various mutant viruses in humans or animals, and the mutual symbiosis of cross infection of various bacteria and viruses are also one of the very serious causes of serious harm to new coronaviruses and mutant viruses. Virology, pathology, etiology, gene sequencing, gene mapping, and a large number of analytical studies have shown that there are many cases in China, the United States, India, Russia, Brazil, and other countries.
(8) For the symptomatic prevention and treatment of the new coronavirus, the combination of various vaccines and various antiviral drugs is critical.
(9) According to the current epidemic situation and research judgments, the epidemic situation may improve in the next period of time and 2021-2022, and we are optimistic about its success. However, completely worry-free, it is still too early to win easily. It is not just relying on vaccination. Wearing masks to close the city and other prevention and control measures and methods can sit back and relax, and you can win a big victory. Because all kinds of research and exploration still require a lot of time and various experimental studies. It is not a day's work. A simple taste is very dangerous and harmful. The power and migratory explosiveness of viruses sometimes far exceed human thinking and perception. In the future, next year, or in the future, whether viruses and various evolutionary mutation viruses will re-attack, we still need to study, analyze, prevent and control, rather than being complacent, thinking that the vaccine can win a big victory is inevitably naive and ridiculous. Vaccine protection is very important, but it must not be taken carelessly. The mutation of the new crown virus is very rampant, and the cross-infection of recessive and virulent bacteria makes epidemic prevention and anti-epidemic very complicated.
(10) New crown virus pneumonia and the virus's stubbornness, strength, migration, susceptibility, multi-infectiousness, and occult. The effectiveness of various vaccines and the particularity of virus mutations The long-term hidden dangers and repeated recurrences of the new coronavirus
(11) The formation mechanism and invisible transmission of invisible viruses, asymptomatic infections and asymptomatic infections, asymptomatic transmission routes, asymptomatic infections, pathological pathogens. The spread and infection of viruses and mutated viruses, the blind spots and blind spots of virus vaccines, viral quantum chemistry and
The chemical and physical corresponding reactions at the meeting points of highly effective vaccine drugs, etc. The variability of mutated viruses is very complicated, and vaccination cannot completely prevent the spread of infection.
(12) New crown virus pneumonia and various respiratory infectious diseases are susceptible to infections in animals and humans, and are frequently recurring. This is one of the frequently-occurring and difficult diseases of common infectious diseases. Even with various vaccines and various antiviral immune drugs, it is difficult to completely prevent the occurrence and spread of viral pneumonia. Therefore, epidemic prevention and anti-epidemic is a major issue facing human society, and no country should take it lightly. The various costs that humans pay on this issue are very expensive, such as Ebola virus, influenza A virus,
Hepatitis virus,
Marburg virus
Sars coronavirus, plague, anthracnose, cholera
and many more. The B.1.1.7 mutant virus that was first discovered in the UK was renamed Alpha mutant virus; the B.1.351 that was first discovered in South Africa was renamed Beta mutant virus; the P.1 that was first discovered in Brazil was renamed Gamma mutant virus; the mutation was first discovered in India There are two branches of the virus. B.1.617.2, which was listed as "mutated virus of concern", was renamed Delta mutant virus, and B.1.617.1 of "mutated virus to be observed" was renamed Kappa mutant virus.
However, experts in many countries believe that the current vaccination is still effective, at least it can prevent severe illness and reduce deaths.
Delta mutant strain
According to the degree of risk, the WHO divides the new crown variant strains into two categories: worrying variant strains (VOC, variant of concern) and noteworthy variant strains (VOI, variant of interest). The former has caused many cases and a wide range of cases worldwide, and data confirms its transmission ability, strong toxicity, high power, complex migration, and high insidious transmission of infection. Resistance to vaccines may lead to the effectiveness of vaccines and clinical treatments. Decrease; the latter has confirmed cases of community transmission worldwide, or has been found in multiple countries, but has not yet formed a large-scale infection. Need to be very vigilant. Various cases and deaths in many countries in the world are related to this. In some countries, the epidemic situation is repeated, and it is also caused by various reasons and viruses, of course, including new cases and so on.
At present, VOC is the mutant strain that has the greatest impact on the epidemic and the greatest threat to the world, including: Alpha, Beta, Gamma and Delta. , Will the change of the spur protein in the VOC affect the immune protection effect of the existing vaccine, or whether it will affect the sensitivity of the VOC to the existing vaccine? For this problem, it is necessary to directly test neutralizing antibodies, such as those that can prevent the protection of infection. Antibodies recognize specific protein sequences on viral particles, especially those spike protein sequences used in mRNA vaccines.
(13) Countries around the world, especially countries and regions with more severe epidemics, have a large number of clinical cases, severe cases, and deaths, especially including many young and middle-aged patients, including those who have been vaccinated. The epidemic is more complicated and serious. Injecting various vaccines, taking strict control measures such as closing the city and wearing masks are very important and the effect is very obvious. However, the new coronavirus and mutant viruses are so repeated, their pathological pathogen research will also be very complicated and difficult. After the large-scale use of the vaccine, many people are still infected. In addition to the lack of prevention and control measures, it is very important that the viability of the new coronavirus and various mutant viruses is very important. It can escape the inactivation of the vaccine. It is very resistant to stubbornness. Therefore, the recurrence of new coronavirus pneumonia is very dangerous. What is more noteworthy is that medical scientists, virologists, pharmacists, biologists, zoologists and clinicians should seriously consider the correspondence between virus specificity and vaccine drugs, and the coupling of commonality and specificity. Only in this way can we find targets. Track and kill viruses. Only in this sense can the new crown virus produce a nemesis, put an end to and eradicate the new crown virus pneumonia. Of course, this is not a temporary battle, but a certain amount of time and process to achieve the goal in the end.
(14) The development and evolution of the natural universe and earth species, as well as life species. With the continuous evolution of human cell genes, microbes and bacterial viruses are constantly mutated and inherited. The new world will inevitably produce a variety of new pathogens.
And viruses. For example, neurological genetic disease, digestive system disease, respiratory system disease, blood system disease, cardiopulmonary system disease, etc., new diseases will continue to emerge as humans develop and evolve. Human migration to space, space diseases, space psychological diseases, space cell diseases, space genetic diseases, etc. Therefore, for the new coronavirus and mutated viruses, we must have sufficient knowledge and response, and do not think that it will be completely wiped out.
, And is not a scientific attitude. Viruses and humans mutually reinforce each other, and viruses and animals and plants mutually reinforce each other. This is the iron law of the natural universe. Human beings can only adapt to natural history, but cannot deliberately modify natural history.
Active immune products made from specific bacteria, viruses, rickettsiae, spirochetes, mycoplasma and other microorganisms and parasites are collectively called vaccines. Vaccination of animals can make the animal body have specific immunity. The principle of vaccines is to artificially attenuate, inactivate, and genetically attenuate pathogenic microorganisms (such as bacteria, viruses, rickettsia, etc.) and their metabolites. Purification and preparation methods, made into immune preparations for the prevention of infectious diseases. In terms of ingredients, the vaccine retains the antigenic properties and other characteristics of the pathogen, which can stimulate the body's immune response and produce protective antibodies. But it has no pathogenicity and does not cause harm to the body. When the body is exposed to this pathogen again, the immune system will produce more antibodies according to the previous memory to prevent the pathogen from invading or to fight against the damage to the body. (1) Inactivated vaccines: select pathogenic microorganisms with strong immunogenicity, culture them, inactivate them by physical or chemical methods, and then purify and prepare them. The virus species used in inactivated vaccines are generally virulent strains, but the use of attenuated attenuated strains also has good immunogenicity, such as the inactivated polio vaccine produced by the Sabin attenuated strain. The inactivated vaccine has lost its infectivity to the body, but still maintains its immunogenicity, which can stimulate the body to produce corresponding immunity and resist the infection of wild strains. Inactivated vaccines have a good immune effect. They can generally be stored for more than one year at 2～8°C without the risk of reversion of virulence; however, the inactivated vaccines cannot grow and reproduce after entering the human body. They stimulate the human body for a short time and must be strong and long-lasting. In general, adjuvants are required for immunity, and multiple injections in large doses are required, and the local immune protection of natural infection is lacking. Including bacteria, viruses, rickettsiae and toxoid preparations.
(2) Live attenuated vaccine: It is a vaccine made by using artificial targeted mutation methods or by screening live microorganisms with highly weakened or basically non-toxic virulence from the natural world. After inoculation, the live attenuated vaccine has a certain ability to grow and reproduce in the body, which can cause the body to have a reaction similar to a recessive infection or a mild infection, and it is widely used.
(3) Subunit vaccine: Among the multiple specific antigenic determinants carried by macromolecular antigens, only a small number of antigenic sites play an important role in the protective immune response. Separate natural proteins through chemical decomposition or controlled proteolysis, and extract bacteria and virusesVaccines made from fragments with immunological activity are screened out of the special protein structure of, called subunit vaccines. Subunit vaccines have only a few major surface proteins, so they can eliminate antibodies induced by many unrelated antigens, thereby reducing the side effects of the vaccine and related diseases and other side effects caused by the vaccine. (4) Genetically engineered vaccine: It uses DNA recombination biotechnology to direct the natural or synthetic genetic material in the pathogen coat protein that can induce the body's immune response into bacteria, yeast or mammalian cells to make it fully expressed. A vaccine prepared after purification. The application of genetic engineering technology can produce subunit vaccines that do not contain infectious substances, stable attenuated vaccines with live viruses as carriers, and multivalent vaccines that can prevent multiple diseases. This is the second-generation vaccine following the first-generation traditional vaccine. It has the advantages of safety, effectiveness, long-term immune response, and easy realization of combined immunization. It has certain advantages and effects.
New coronavirus drug development, drug targets and chemical modification.
Ligand-based drug design (or indirect drug design planning) relies on the knowledge of other molecules that bind to the target biological target. These other molecules can be used to derive pharmacophore models and structural modalities, which define the minimum necessary structural features that the molecule must have in order to bind to the target. In other words, a model of a biological target can be established based on the knowledge of the binding target, and the model can be used to design new molecular entities and other parts that interact with the target. Among them, the quantitative structure-activity relationship (QSAR) is included, in which the correlation between the calculated properties of the molecule and its experimentally determined biological activity can be derived. These QSAR relationships can be used to predict the activity of new analogs. The structure-activity relationship is very complicated.
Based on structure
Structure-based drug design relies on knowledge of the three-dimensional structure of biological targets obtained by methods such as X-ray crystallography or NMR spectroscopy and quantum chemistry. If the experimental structure of the target is not available, it is possible to create a homology model of the target and other standard models that can be compared based on the experimental structure of the relevant protein. Using the structure of biological targets, interactive graphics and medical chemists’ intuitive design can be used to predict drug candidates with high affinity and selective binding to the target. Various automatic calculation programs can also be used to suggest new drug candidates.
The current structure-based drug design methods can be roughly divided into three categories. The 3D method is to search a large database of small molecule 3D structures to find new ligands for a given receptor, in order to use a rapid approximate docking procedure to find those suitable for the receptor binding pocket. This method is called virtual screening. The second category is the de novo design of new ligands. In this method, by gradually assembling small fragments, a ligand molecule is established within the constraints of the binding pocket. These fragments can be single atoms or molecular fragments. The main advantage of this method is that it can propose novel structures that are not found in any database. The third method is to optimize the known ligand acquisition by evaluating the proposed analogs in the binding cavity.
Bind site ID
Binding site recognition is a step in structure-based design. If the structure of the target or a sufficiently similar homologue is determined in the presence of the bound ligand, the ligand should be observable in that structure, in which case the location of the binding site is small. However, there may not be an allosteric binding site of interest. In addition, only apo protein structures may be available, and it is not easy to reliably identify unoccupied sites that have the potential to bind ligands with high affinity. In short, the recognition of binding sites usually depends on the recognition of pits. The protein on the protein surface can hold molecules the size of drugs, etc. These molecules also have appropriate "hot spots" that drive ligand binding, hydrophobic surfaces, hydrogen bonding sites, and so on.
Drug design is a creative process of finding new drugs based on the knowledge of biological targets. The most common type of drug is small organic molecules that activate or inhibit the function of biomolecules, thereby producing therapeutic benefits for patients. In the most important sense, drug design involves the design of molecules with complementary shapes and charges that bind to their interacting biomolecular targets, and therefore will bind to them. Drug design often but does not necessarily rely on computer modeling techniques. A more accurate term is ligand design. Although the design technology for predicting binding affinity is quite successful, there are many other characteristics, such as bioavailability, metabolic half-life, side effects, etc., which must be optimized first before the ligand can become safe and effective. drug. These other features are usually difficult to predict and realize through reasonable design techniques. However, due to the high turnover rate, especially in the clinical stage of drug development, in the early stage of the drug design process, more attention is paid to the selection of drug candidates. The physical and chemical properties of these drug candidates are expected to be reduced during the development process. Complications are therefore more likely to lead to the approval of the marketed drug. In addition, in early drug discovery, in vitro experiments with computational methods are increasingly used to select compounds with more favorable ADME (absorption, distribution, metabolism, and excretion) and toxicological characteristics. A more accurate term is ligand design. Although the design technique for predicting binding affinity is quite successful, there are many other characteristics, such as bioavailability, metabolic half-life, side effects, iatrogenic effects, etc., which must be optimized first, and then the ligand To become safe and effective.
For drug targets, two aspects should be considered when selecting drug targets:
1. The effectiveness of the target, that is, the target is indeed related to the disease, and the symptoms of the disease can be effectively improved by regulating the physiological activity of the target.
2. The side effects of the target. If the regulation of the physiological activity of the target inevitably produces serious side effects, it is inappropriate to select it as the target of drug action or lose its important biological activity. The reference frame of the target should be expanded in multiple dimensions to have a big choice.
3. Search for biomolecular clues related to diseases: use genomics, proteomics and biochip technology to obtain biomolecular information related to diseases, and perform bioinformatics analysis to obtain clue information.
4. Perform functional research on related biomolecules to determine the target of candidate drugs. Multiple targets or individual targets.
5. Candidate drug targets, design small molecule compounds, and conduct pharmacological research at the molecular, cellular and overall animal levels.
Covalent bonding type
The covalent bonding type is an irreversible form of bonding, similar to the organic synthesis reaction that occurs. Covalent bonding types mostly occur in the mechanism of action of chemotherapeutic drugs. For example, alkylating agent anti-tumor drugs produce covalent bonding bonds to guanine bases in DNA, resulting in cytotoxic activity.
. Verify the effectiveness of the target.
Based on the targets that interact with drugs, that is, receptors in a broad sense, such as enzymes, receptors, ion channels, membranes, antigens, viruses, nucleic acids, polysaccharides, proteins, enzymes, etc., find and design reasonable drug molecules. Targets of action and drug screening should focus on multiple points. Drug intermediates and chemical modification. Combining the development of new drugs with the chemical structure modification of traditional drugs makes it easier to find breakthroughs and develop new antiviral drugs. For example, careful selection, modification and modification of existing related drugs that can successfully treat and recover a large number of cases, elimination and screening of invalid drugs from severe death cases, etc., are targeted, rather than screening and capturing needles in a haystack, aimless, with half the effort. Vaccine design should also be multi-pronged and focused. The broad-spectrum, long-term, safety, efficiency and redundancy of the vaccine should all be considered. In this way, it will be more powerful to deal with the mutation and evolution of the virus. Of course, series of vaccines, series of drugs, second-generation vaccines, third-generation vaccines, second-generation drugs, third-generation drugs, etc. can also be developed. Vaccines focus on epidemic prevention, and medicines focus on medical treatment. The two are very different; however, the two complement each other and complement each other. Therefore, in response to large-scale epidemics of infectious diseases, vaccines and various drugs are the nemesis and killers of viral diseases. Of course, it also includes other methods and measures, so I won't repeat them here.
Mainly through the comprehensive and accurate understanding of the structure of the drug and the receptor at the molecular level and even the electronic level, structure-based drug design and the understanding of the structure, function, and drug action mode of the target and the mechanism of physiological activity Mechanism-based drug design.
Compared with the traditional extensive pharmacological screening and lead compound optimization, it has obvious advantages.
Viral RNA replicase, also known as RNA-dependent RNA polymerase (RdRp) is responsible for the replication and transcription of RNA virus genome, and plays a very important role in the process of virus self-replication in host cells, and It also has a major impact on the mutation of the virus, it will change and accelerate the replication and recombination. Because RdRp from different viruses has a highly conserved core structure, the virus replicase is an important antiviral drug target and there are other selection sites, rather than a single isolated target target such as the new coronavirus As with various mutant viruses, inhibitors developed for viral replicase are expected to become a broad-spectrum antiviral drug. The currently well-known anti-coronavirus drug remdesivir (remdesivir) is a drug for viral replicase.
New antiviral therapies are gradually emerging. In addition to traditional polymerase and protease inhibitors, nucleic acid drugs, cell entry inhibitors, nucleocapsid inhibitors, and drugs targeting host cells are also increasingly appearing in the research and development of major pharmaceutical companies. The treatment of mutated viruses is becoming increasingly urgent. The development of drugs for the new coronavirus pneumonia is very important. It is not only for the current global new coronavirus epidemic, but more importantly, it is of great significance to face the severe pneumonia-respiratory infectious disease that poses a huge threat to humans.
There are many vaccines and related drugs developed for the new coronavirus pneumonia, and countries are vying for a while, mainly including the following:
Identification test, appearance, difference in loading, moisture, pH value, osmolality, polysaccharide content, free polysaccharide content, potency test, sterility test, pyrogen test, bacterial endotoxin test, abnormal toxicity test.
Among them: such as sterility inspection, pyrogen inspection, bacterial endotoxin, and abnormal toxicity inspection are indicators closely related to safety.
Polysaccharide content, free polysaccharide content, and efficacy test are indicators closely related to vaccine effectiveness.
Usually, a vaccine will go through a long research and development process of at least 8 years or even more than 20 years from research and development to marketing. The outbreak of the new crown epidemic requires no delay, and the design and development of vaccines is speeding up. It is not surprising in this special period. Of course, it is understandable that vaccine design, development and testing can be accelerated, shortened the cycle, and reduced some procedures. However, science needs to be rigorous and rigorous to achieve great results. The safety and effectiveness of vaccines are of the utmost importance. There must not be a single error. Otherwise, it will be counterproductive and need to be continuously improved and perfected.
Pre-clinical research: The screening of strains and cells is the basic guarantee to ensure the safety, effectiveness, and continuous supply of vaccines. Taking virus vaccines as an example, the laboratory stage needs to carry out strain screening, necessary strain attenuation, strain adaptation to the cultured cell matrix and stability studies in the process of passaging, and explore the stability of process quality, establish animal models, etc. . Choose mice, guinea pigs, rabbits or monkeys for animal experiments according to each vaccine situation. Pre-clinical research generally takes 5-10 years or longer on the premise that the process is controllable, the quality is stable, and it is safe and effective. In order to be safe and effective, a certain redundant design is also needed, so that the safety and effectiveness of the vaccine can be importantly guaranteed.
These include the establishment of vaccine strain/cell seed bank, production process research, quality research, stability research, animal safety evaluation and effectiveness evaluation, and clinical trial programs, etc.
The ARS-CoV-2 genome contains at least 10 ORFs. ORF1ab is converted into a polyprotein and processed into 16 non-structural proteins (NSP). These NSPs have a variety of functional biological activities, physical and chemical reactions, such as genome replication, induction of host mRNA cleavage, membrane rearrangement, autophagosome production, NSP polyprotein cleavage, capping, tailing, methylation, RNA double-stranded Uncoiling, etc., and others, play an important role in the virus life cycle. In addition, SARS-CoV-2 contains 4 structural proteins, namely spike (S), nucleocapsid (N), envelope (E) and membrane (M), all of which are encoded by the 3'end of the viral genome. Among the four structural proteins, S protein is a large multifunctional transmembrane protein that plays an important role in the process of virus adsorption, fusion, and injection into host cells, and requires in-depth observation and research.
1S protein is composed of S1 and S2 subunits, and each subunit can be further divided into different functional domains. The S1 subunit has 2 domains: NTD and RBD, and RBD contains conservative RBM. The S2 subunit has 3 structural domains: FP, HR1 and HR2. The S1 subunit is arranged at the top of the S2 subunit to form an immunodominant S protein.
The virus uses the host transmembrane protease Serine 2 (TMPRSS2) and the endosomal cysteine protease CatB/L to enter the cell. TMPRSS2 is responsible for the cleavage of the S protein to expose the FP region of the S2 subunit, which is responsible for initiating endosome-mediated host cell entry into it. It shows that TMPRSS2 is a host factor necessary for virus entry. Therefore, the use of drugs that inhibit this protease can achieve the purpose of treatment.
mRNA-1273
The mRNA encoding the full length of SARS-CoV-2, and the pre-spike protein fusion is encapsulated into lipid nanoparticles to form mRNA-1273 vaccine. It can induce a high level of S protein specific antiviral response. It can also consist of inactivated antigens or subunit antigens. The vaccine was quickly approved by the FDA and has entered phase II clinical trials. The company has announced the antibody data of 8 subjects who received different immunization doses. The 25ug dose group achieved an effect similar to the antibody level during the recovery period. The 100ug dose group exceeded the antibody level during the recovery period. In the 25ug and 100ug dose groups, the vaccine was basically safe and tolerable, while the 250ug dose group had 3 levels of systemic symptoms.
Viral vector vaccines can provide long-term high-level expression of antigen proteins, induce CTLs, and ultimately eliminate viral infections.
1, Ad5-nCov
A vaccine of SARS-CoV-2 recombinant spike protein expressed by recombinant, replication-deficient type 5 adenovirus (Ad5) vector. Load the optimized full-length S protein gene together with the plasminogen activation signal peptide gene into the E1 and E3 deleted Ad5 vectors. The vaccine is constructed by the Admax system derived from Microbix Biosystem. In phase I clinical trials, RBD (S1 subunit receptor binding domain) and S protein neutralizing antibody increased by 4 times 14 days after immunization, reaching a peak on 28 days. CD4+T and CD8+T cells reached a peak 14 days after immunization. The existing Ad5 immune resistance partially limits the response of antibodies and T cells. This study will be further conducted in the 18-60 age group, receiving 1/3 of the study dose, and follow-up for 3-6 months after immunization.
DNA vaccine
The introduction of antigen-encoding DNA and adjuvants as vaccines is the most innovative vaccine method. The transfected cells stably express the transgenic protein, similar to live viruses. The antigen will be endocytosed by immature DC, and finally provide antigen to CD4 + T, CD8 + T cells (by MHC differentiation) To induce humoral and cellular immunity. Some specificities of the virus and the new coronavirus mutant are different from general vaccines and other vaccines. Therefore, it is worth noting the gene expression of the vaccine. Otherwise, the effectiveness and efficiency of the vaccine will be questioned.
Live attenuated vaccine
DelNS1-SARS-CoV2-RBD
Basic influenza vaccine, delete NS1 gene. Express SARS-CoV-2 RBD domain. Cultured in CEF and MDCK (canine kidney cells) cells. It is more immunogenic than wild-type influenza virus and can be administered by nasal spray.
The viral genome is susceptible to mutation, antigen transfer and drift can occur, and spread among the population. Mutations can vary depending on the environmental conditions and population density of the geographic area. After screening and comparing 7,500 samples of infected patients, scientists found 198 mutations, indicating the evolutionary mutation of the virus in the human host. These mutations may form different virus subtypes, which means that even after vaccine immunization, viral infections may occur. A certain amount of increment and strengthening is needed here.
Inactivated vaccines, adenovirus vector vaccines, recombinant protein vaccines, nucleic acid vaccines, attenuated influenza virus vector vaccines, etc. According to relevant information, there are dozens of new coronavirus vaccines in the world, and more varieties are being developed and upgraded. Including the United States, Britain, China, Russia, India and other countries, there are more R&D and production units.
AZ vaccine
Modena vaccine
Lianya Vaccine
High-end vaccine
Pfizer vaccine
Pfizer-BioNTech
A large study found that the vaccine developed by Pfizer and German biotechnology company BioNTech is 95% effective in preventing COVID-19.
The vaccine is divided into two doses, which are injected every three weeks.
This vaccine uses a molecule called mRNA as its basis. mRNA is a molecular cousin of DNA, which contains instructions to build specific proteins; in this case, the mRNA in the vaccine encodes the coronavirus spike protein, which is attached to the surface of the virus and used to infect human cells. Once the vaccine enters the human body, it will instruct the body's cells to make this protein, and the immune system will learn to recognize and attack it.
Moderna
The vaccine developed by the American biotechnology company Moderna and the National Institute of Allergy and Infectious Diseases (NIAID) is also based on mRNA and is estimated to be 94.5% effective in preventing COVID-19.
Like Pfizer's vaccine, this vaccine is divided into two doses, but injected every four weeks instead of three weeks. Another difference is that the Moderna vaccine can be stored at minus 20 degrees Celsius instead of deep freezing like Pfizer vaccine. At present, the importance of one of the widely used vaccines is self-evident.
Oxford-AstraZeneca
The vaccine developed by the University of Oxford and the pharmaceutical company AstraZeneca is approximately 70% effective in preventing COVID-19-that is, in clinical trials, adjusting the dose seems to improve this effect.
In the population who received two high-dose vaccines (28 days apart), the effectiveness of the vaccine was about 62%; according to early analysis, the effectiveness of the vaccine in those patients who received the half-dose first and then the full-dose Is 90%. However, in clinical trials, participants taking half doses of the drug are wrong, and some scientists question whether these early results are representative.
Sinopharm Group (Beijing Institute of Biological Products, China)
China National Pharmaceutical Group Sinopharm and Beijing Institute of Biological Products have developed a vaccine from inactivated coronavirus (SARS-CoV-2). The inactivated coronavirus is an improved version that cannot be replicated.
Estimates of the effectiveness of vaccines against COVID-19 vary.
Gamaleya Institute
The Gamaleya Institute of the Russian Ministry of Health has developed a coronavirus vaccine candidate called Sputnik V. This vaccine contains two common cold viruses, adenoviruses, which have been modified so that they will not replicate in the human body; the modified virus also contains a gene encoding the coronavirus spike protein.
New crown drugs
There are many small molecule antiviral drug candidates in the clinical research stage around the world. Including traditional drugs in the past and various drugs yet to be developed, antiviral drugs, immune drugs, Gene drugs, compound drugs, etc.
(A) Molnupiravir
Molnupiravir is a prodrug of the nucleoside analog N4-hydroxycytidine (NHC), jointly developed by Merck and Ridgeback Biotherapeutics.
The positive rate of infectious virus isolation and culture in nasopharyngeal swabs was 0% (0/47), while that of patients in the placebo group was 24% (6/25). However, data from the Phase II/III study indicate that the drug has no benefit in preventing death or shortening the length of stay in hospitalized patients.
Therefore, Merck has decided to fully advance the research of 800mg molnupiravir in the treatment of patients with mild to moderate COVID-19.
(B) AT-527
AT-527 is a small molecule inhibitor of viral RNA polymerase, jointly developed by Roche and Atea. Not only can it be used as an oral therapy to treat hospitalized COVID-19 patients, but it also has the potential as a preventive treatment after exposure.
Including 70 high-risk COVID-19 hospitalized patients data, of which 62 patients' data can be used for virological analysis and evaluation. The results of interim virological analysis show that AT-527 can quickly reduce viral load. On day 2, compared with placebo, patients treated with AT-527 had a greater decline in viral load than the baseline level, and the continuous difference in viral load decline was maintained until day 8.
In addition, compared with the control group, the potent antiviral activity of AT-527 was also observed in patients with a baseline median viral load higher than 5.26 log10. When testing by RT-qPCR to assess whether the virus is cleared,
The safety aspect is consistent with previous studies. AT-527 showed good safety and tolerability, and no new safety problems or risks were found. Of course, there is still a considerable distance between experiment and clinical application, and a large amount of experimental data can prove it.
(C) Prokrutamide
Prokalamide is an AR (androgen receptor) antagonist. Activated androgen receptor AR can induce the expression of transmembrane serine protease (TMPRSS2). TMPRSS2 has a shearing effect on the new coronavirus S protein and ACE2, which can promote the binding of viral spike protein (S protein) to ACE, thereby promoting The virus enters the host cell. Therefore, inhibiting the androgen receptor may inhibit the viral infection process, and AR antagonists are expected to become anti-coronavirus drugs.
Positive results were obtained in a randomized, double-blind, placebo-controlled phase III clinical trial. The data shows that Prokalutamide reduces the risk of death in severely ill patients with new coronary disease by 92%, reduces the risk of new ventilator use by 92%, and shortens the length of hospital stay by 9 days. This shows that procrulamide has a certain therapeutic effect for patients with severe new coronary disease, which can significantly reduce the mortality of patients, and at the same time greatly reduce the new mechanical ventilation and shorten the patient's hospital stay.
With the continuous development of COVID-19 on a global scale, in addition to vaccines and prevention and control measures, we need a multi-pronged plan to control this disease. Oral antiviral therapy undoubtedly provides a convenient treatment option.
In addition, there are other drugs under development and experimentation. In dealing with the plague virus, in addition to the strict control of protective measures, it is very important that various efficient and safe vaccines and various drugs (including medical instruments, etc.) are the ultimate nemesis and killer of the virus.
(A) "Antiviral biological missiles" are mainly drugs for new coronaviruses and mutant viruses, which act on respiratory and lung diseases. The drugs use redundant designs to inhibit new coronaviruses and variant viruses.
(B) "New Coronavirus Epidemic Prevention Tablets" mainly use natural purified elements and chemical structure modifications.
(C) "Composite antiviral oral liquid" antiviral intermediate, natural antiviral plant, plus other preparations
(D) "New Coronavirus Long-acting Oral Tablets" Chemical modification of antiviral drugs, multiple targets, etc.
(E) "New Coronavirus Inhibitors" (injections) are mainly made of chemical drug structure modification and other preparations.
The development of these drugs mainly includes: drug target screening, structure-activity relationship, chemical modification, natural purification, etc., which require a lot of work and experimentation.
Humans need to vigorously develop drugs to deal with various viruses. These drugs are very important for the prevention and treatment of viruses and respiratory infectious diseases, influenza, pneumonia, etc.
The history of human development The history of human evolution, like all living species, will always be accompanied by the survival and development of microorganisms. It is not surprising that viruses and infectious diseases are frequent and prone to occur. The key is to prevent and control them before they happen.
This strain was first discovered in India in October 2020 and was initially called a "double mutant" virus by the media. According to the announcement by the Ministry of Health of India at the end of March this year, the "India New Coronavirus Genomics Alliance" composed of 10 laboratories found in samples collected in Maharashtra that this new mutant strain carries E484Q and L452R mutations. , May lead to immune escape and increased infectivity. This mutant strain was named B.1.617 by the WHO and was named with the Greek letter δ (delta) on May 31.
Shahid Jamil, the dean of the Trivedi School of Biological Sciences at Ashoka University in India and a virologist, said in an interview with the Shillong Times of India that this mutant strain called "double mutation" is not accurate enough. B. 1.617 contains a total of 15 mutations, of which 6 occur on the spike protein, of which 3 are more critical: L452R and E484Q mutations occur on the spike protein and the human cell "Angiotensin Converting Enzyme 2 (ACE2)" receptor In the bound region, L452R improves the ability of the virus to invade cells, and E484Q helps to enhance the immune escape of the virus; the third mutation P681R can also make the virus enter the cell more effectively. (Encyclopedia website)
There are currently dozens of antiviral COVID-19 therapies under development. The large drugmakers Merck and Pfizer are the closest to the end, as expected, a pair of oral antiviral COVID-19 therapies are undergoing advanced human clinical trials.
Merck's drug candidate is called monupiravir. It was originally developed as an influenza antiviral drug several years ago. However, preclinical studies have shown that it has a good effect on SARS and MERS coronavirus.
Monupiravir is currently undergoing in-depth large-scale Phase 3 human trials. So far, the data is so promising that the US government recently pre-ordered 1.7 million courses of drugs at a cost of $1.2 billion. If everything goes according to plan, the company hopes that the drug will be authorized by the FDA for emergency use and be on the market before the end of 2021.
Pfizer's large COVID-19 antiviral drug candidate is more unique. Currently known as PF-07321332, this drug is the first oral antiviral drug to enter human clinical trials, specifically targeting SARS-CoV-2.
Variant of Concern WHO Label First Detected in World First Detected in Washington State
B.1.1.7 Alpha United Kingdom, September 2020 January 2021
B.1.351 Beta South Africa, December 2020 February 2021
P.1 Gamma Brazil, April 2020 March 2021
B.1.617.2 Delta India, October 2020 April 2021
Although this particular molecule was developed in 2020 after the emergence of the new coronavirus, a somewhat related drug called PF-00835231 has been in operation for several years, targeting the original SARS virus. However, the new drug candidate PF-07321332 is designed as a simple pill that can be taken under non-hospital conditions in the initial stages of SARS-CoV-2 infection.
"The protease inhibitor binds to a viral enzyme and prevents the virus from replicating in the cell," Pfizer said when explaining the mechanism of its new antiviral drug. "Protease inhibitors have been effective in the treatment of other viral pathogens, such as HIV and hepatitis C virus, whether used alone or in combination with other antiviral drugs. Currently marketed therapeutic drugs for viral proteases are generally not toxic Therefore, such molecules may provide well-tolerated treatments against COVID-19."
Various studies on other types of antiviral drugs are also gaining momentum. For example, the new coronavirus pneumonia "antiviral biological missile", "new coronavirus prevention tablets", "composite antiviral oral liquid", "new coronavirus long-acting oral tablets", "new coronavirus inhibitors" (injections), etc., are worthy of attention. Like all kinds of vaccines, they will play a major role in preventing and fighting epidemics.
In addition, Japanese pharmaceutical company Shionoyoshi Pharmaceutical is currently conducting a phase 1 trial of a protease inhibitor similar to SARS-CoV-2. This is called S-217622, which is another oral antiviral drug, and hopes to provide people with an easy-to-take pill in the early stages of COVID-19. At present, the research and development of vaccines and various new crown drugs is very active and urgent. Time does not wait. With the passage of time, various new crown drugs will appear on the stage one after another, bringing the gospel to the complete victory of mankind.
The COVID-19 pandemic is far from over. The Delta mutant strain has quickly become the most prominent SARS-CoV-2 strain in the world. Although our vaccine is still maintained, it is clear that we need more tools to combat this new type of coronavirus. Delta will certainly not be the last new SARS-CoV-2 variant we encountered. Therefore, it is necessary for all mankind to persevere and fight the epidemic together.
Overcome illness and meet new challenges. The new crown epidemic and various mutated viruses are very important global epidemic prevention and anti-epidemic top priorities, especially for the current period of time. Vaccine injections, research and development of new drugs, strict prevention and control, wear masks, reduce gatherings, strictly control large gatherings, prevent the spread of various viruses Masks, disinfection and sterilization, lockdown of the city, vaccinations, accounting and testing are very important, but this does not mean that humans can completely overcome the virus. In fact, many spreading and new latently transmitted infections are still unsuccessful. There are detections, such as invisible patients, asymptomatic patients, migratory latent patients, new-onset patients, etc. The struggle between humans and the virus is still very difficult and complicated, and long-term efforts and exploration are still needed, especially for medical research on the new coronavirus. The origin of the disease, the course of the disease, the virus invaded The deep-level path and the reasons for the evolution and mutation of the new coronavirus and the particularity of prevention and treatment, etc.). Therefore, human beings should be highly vigilant and must not be taken lightly. The fierce battle between humans and various viruses must not be slackened. Greater efforts are needed to successfully overcome this pandemic, fully restore the normal life of the whole society, restore the normal production and work order, restore the normal operation of society, economy and culture, and give up food due to choking. Or eager for success, will pay a high price.
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Compilation postscript
Once Fang Ruida's research literature on the new crown virus and mutant virus was published, it has been enthusiastically praised by readers and netizens in dozens of countries around the world, and has proposed some amendments and suggestions. Hope to publish a multilingual version of the book as an emergency To meet the needs of many readers around the world, in the face of the new crown epidemic and the prevention and treatment of various mutant viruses, including the general public, college and middle school students, medical workers, medical colleagues and so on. According to the English original manuscript, it will be re-compiled and published. Inconsistencies will be revised separately. Thank you very much.
Jacques Lucy, Geneva, Switzerland, August 2021
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Leader mondial, scientifique, scientifique médical, virologue, pharmacien et professeur Fangruida (F.D Smith) sur l'épidémie mondiale et l'ennemi juré et la prévention des nouveaux coronavirus et virus mutants (Jacques Lucy 2021v1.5)
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L'ennemi juré et le tueur du nouveau coronavirus et des virus mutés - Développement conjoint de vaccins et de médicaments (Fangruida) Juillet 2021
* La particularité des nouveaux coronavirus et des virus mutants * Le large spectre, la haute efficacité, la redondance et la sécurité de la conception et du développement du nouveau vaccin contre le coronavirus, Redondance et sécurité
Go to the Book with image in the Internet Archive
Title: United States Naval Medical Bulletin Vol. 8, Nos. 1-4, 1914
Creator: U.S. Navy. Bureau of Medicine and Surgery
Publisher:
Sponsor:
Contributor:
Date: 1914
Language: eng
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Table of Contents</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface v</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The application of psychiatry to certain military problems, by W. A.
White, M. D 1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Schistosomiasis on the Yangtze River, with report of cases, by R. H.
Laning, assistant surgeon, United States Navy 16</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A brief discussion of matters pertaining to health and sanitation,
observed on the summer practice cruise of 1913 for midshipmen of the third
class, by J. L. Neilson, surgeon, United States Navy 36</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Technique of neosalvarsan administration, and a brief outline of the
treatment for syphilis used at the United States Naval Hospital, Norfolk, Va., by
W. Chambers, passed assistant surgeon, United States Navy 45</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some notes on the disposal of wastes, by A. Farenholt, surgeon, United States
Navy 47</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The medical department on expeditionary duty, by R. E. Hoyt, surgeon, United
States Navy 51</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A new brigade medical outfit, by T. W. Richards, surgeon, United States
Navy 62</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Early diagnosis of cerebrospinal meningitis; report of 10 cases, by G.
F. Cottle, passed assistant surgeon, United States Navy 65</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Comments on mistakes made with the Nomenclature, 1913, Abstract of patients
(Form F), and the Statistical report (Form K), by C. E. Alexander, pharmacist,
United States Navy 70</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Classification of the United States Navy Nomenclature, 1913, by C. E. Alexander,
pharmacist, United States Navy 75</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">On the methods employed for the detection and determination of
disturbances in the sense of equilibrium of flyers. Translated by H. G. Beyer,
medical director, United States Navy, retired 87</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 107</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthological collection 107</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A portable air sampling apparatus for use aboard ship, by E. W. Brown, passed
assistant surgeon, United States Navy 109</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A new design for a sanitary pail 111</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of paresis, with apparent remission, following neosalvarsan, by R.
F. Sheehan, passed assistant surgeon, United States Navy 113</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Case reports from Guam, by E. O. J. Eytinge, passed assistant surgeon, United
States Navy 116</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Stab wound of ascending colon; suture; recovery, by H. C. Curl,
surgeon, United States Navy 123</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Perforation of a duodenal ulcer, by H. F. Strine, surgeon, United
States Navy 124</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Two cases of bone surgery, by R. Spear, surgeon, United States Navy 125</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment: </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Brig. Gen. George II. Torney, Surgeon General United States Army 127</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical ethics in the Navy 127</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical officers in civil practice 128</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —Some anatomic and physiologic principles concerning
pyloric ulcer. By H. C. Curl. Low-priced clinical thermometers; a warning. By.
L. W. Johnson. The value of X-ray examinations in the</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">diagnosis of ulcer of the stomach and duodenum. The primary cause of
rheumatoid arthritis. Strychnine in heart failure. On the treatment of
leukaemia with benzol. By A. W. Dunbar and G. B. Crow 131</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. — Surgical aspects of furuncles and carbuncles. Iodine
idiosyncrasy. By L. W. Johnson. Rectus transplantation for deficiency of
internal oblique muscle in certain cases of inguinal hernia. The technic of
nephro- pyelo- and ureterolithotomy. Recurrence of inguinal hernia. By H. C.
Curl and R. A. Warner 138</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. —Ozone: Its bactericidal, physiologic and
deodorizing action. The alleged purification of air by the ozone machine. By E.
W. Brown. The prevention of dental caries. Gun-running operations in the
Persian Gulf in 1909 and 1910. The croton bug (Ectobia germanica) as a factor
in bacterial dissemination. Fumigation of vessels for the destruction of rats.
Improved moist chamber for mosquito breeding. The necessity for international
reforms in the sanitation of crew spaces on</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">merchant vessels. By C. N. Fiske and R. C. Ransdell 143</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. —The transmissibility of the lepra bacillus by the
bite of the bedbug. By L. W. Johnson. A note on a case of loa loa. Cases of
syphilitic pyrexia simulating tropical fevers. Verruga peruviana, oroya fever
and uta. Ankylostomiasis in Nyasaland. Experimental entamoebic dysentery. By E.
R. Stitt ... 148</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —The relation of the spleen
to the blood destruction and regeneration and to hemolytic jaundice: 6, The
blood picture at various periods after splenectomy. The presence of tubercle
bacilli in the feces. By A. B. Clifford and G. F. Clark 157</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. —Detection of bile pigments in urine. Value of the
guaiacum test for bloodstains. New reagent for the detection of traces of
blood. Estimation of urea. Estimation of uric acid in urine. By E. W. Brown and
O. G. Ruge 158</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. —Probable deleterious effect of salvarsan
on the eye. Effect of salvarsan on the eye. Fate of patients with
parenchymatous keratitis due to hereditary lues. Trachoma, prevalence of, in
the United States. The exploratory needle puncture of the maxillary antrum in
100 tuberculous individuals. Auterobic organisms associated with acute
rhinitis. Toxicity of human tonsils. By E. J. Grow and G. B. Trible 160</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous. —Yearbook of the medical association of
Frankfurt-am-Main. By R. C. Ransdell 163</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Notes on the Clinical Congress of Surgeons. By G. F. Cottle, passed
assistant surgeon, United States Navy 167</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 2</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface v</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of the fourteenth annual meeting of the American Roentgen Ray Society,
by J. R. Phelps, passed assistant surgeon, United States Navy. 171</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Typhoid perforation; five operations with three recoveries, by G. G.
Holladay, assistant surgeon, Medic al Reserve Corps, United States Navy 238</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A satisfactory method for easily obtaining material from syphilitic
lesions, by E. R. Stitt, medical inspector, United States Navy 242</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">An epidemic of measles and mumps in Guam, by C. P. Kindleberger, surgeon,
United States Navy 243</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The feeble-minded from a military standpoint, by A. R. Schier, acting assistant
surgeon, United States Navy 247</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Towne-Lambert elimination treatment of drug addictions, by W. M. Kerr,
passed assistant surgeon, United States Navy 258</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical experiences in the Amazonian Tropics, by C. C. Ammerman, assistant
surgeon, Medical Reserve Corps, United States Navy 270</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 281</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthologieal collection 281</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">An easy method for obtaining blood cultures and for preparing blood
agar, by E. R. Stitt, medical inspector, and G. F. Clark, passed assistant surgeon,
United States Navy 283</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Humidity regulating device on a modern battleship, by R. C. Ransdell, passed
assistant surgeon, United States Navy 284</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Lateral sinus thrombosis, report of case, by G. F. Cottle, passed
assistant surgeon. United States Navy 287</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Twenty-two cases of poisoning by the seeds of Jatropha curcai, by J. A.
Randall, passed assistant surgeon, United States Navy 290</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Shellac bolus in the stomach in fatal case of poisoning by weed
alcohol, by H. F. Hull and O. J. Mink, passed assistant surgeons, United States
Navy 291</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of pneumonia complicated by gangrenous endocarditis, by G. B. Crow,
passed assistant surgeon, United States Navy 292</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —On progressive paralysis in the imperial navy during
the years 1901-1911. By H. G. Beyer. An etiological study of Hodgkin's disease.
The etiology and vaccine treatment of Hodgkin's dis</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">ease. Coryncbacterium hodgkini in lymphatic leukemia and Hodgkin's disease.
Autointoxication and subinfection. Studies of syphilis. The treatment of the
pneumonias. Whooping cough: Etiolcgy, diagnosis, and vaccine treatment. A new
and logical treatment for alcoholism. Intraspinous injection of salvarsanized
serum in the treatment of syphilis of the nervous system, including tabes and
paresis. On the infective nature of certain cases of splenomegaly and Banti's
disease. The etiology and vaccine treatment of Hodgkin's disease. Cultural
results in Hodgkin's disease. By A. W. Dunbar and G. B. Crow 295</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery- Interesting cases of gunshot injury treated at Hankow during
the revolution of 1911 and 1912 in China. The fool's paradise stage in
appendicitis. By L. W. Johnson. The present status of bismuth paste treatment
of suppurative sinuses and empyema. The inguinal route operation for femoral
hernia; with supplementary note on Cooper's ligament. By R. Spear and R. A.
Warner 307</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. — A contribution to the chemistry of
ventilation. The use of ozone in ventilation. By E. \V. Brown. Pulmonary
tuberculosis in the royal navy, with special reference to its detection and
prevention. An investigation into the keeping properties of condensed milks at
the temperature of tropical climates. By C. N. Fiske and R. C. Ransdell 313</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. —Seven days fever of the Indian ports. By L. W.
Johnson. Intestinal schistosomiasis in the Sudan. Disease carriers in our army
in India. Origin and present status of the emetin treatment of amebic
dysentery. The culture of leishmania from the finger blood of a case of Indian
kala-azar. By E. R. Stitt 315</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —The isolation of
typhoid bacilli from feces by means of brilliant green in fluid medium. By C.
N. Fiske. An efficient and convenient stain for use in the eeneral examination
of blood films. By 0. B. Crow. A contribution to the epidemiology of
poliomyelitis. A contribution to the pathology of epidemic poliomyelitis. A
note on the etiology of epidemic<span>
</span>oliomyelitis. Transmutations within the streptococcus-pneumococcus
group. The etiology of acute rheumatism, articular and muscular. By A. B.
Clifford and G. F. Clark 320</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy.— Centrifugal method for estimating albumin in
urine. Detection of albumin in urine. New indican reaction A report on the
chemistry, technology, and pharmacology of and the legislation pertaining to
methyl alcohol. By E. W. Brown and O. O. Ruge. . 325</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. —The use of local anesthesia in
exenteration of the orbit. Salvarsan in<span>
</span>ophthalmic practice. The effect of salvarsan on the eye. Total blindness
from the toxic action of wood alcohol, with recovery of vision under negative
galvanism. Furunculosis of the external auditory canal; the use of alcohol as a
valuable aid in treatment. Local treatment of Vincent's angina with salvarsan.
Perforated ear drum may be responsible for sudden death in water. The indications
for operating in acute mastoiditis. Turbinotomy. Why is nasal catarrh so
prevalent in the United States? By E. J. Grow and G. B. Trible 330</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous. — The organization and work of the hospital ship Re d’
Italia. ByG. B. Trible 333</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Correspondence concerning the article "Some aspects of the
prophylaxis of typhoid fever by injection of killed cultures," by Surg. C.
S. Butler, United States Navy, which appeared in the Bulletin, October, 1913
339</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Malaria on the U. S. S. Tacoma from February, 1913, to February, 1914.
by I. S. K. Reeves, passed assistant surgeon, United States Navy 344</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Extracts from annual sanitary reports for 1913 345</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 3</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface vii</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Economy and waste in naval hospitals, by E. M. Shipp, surgeon, and P.
J. Waldner, chief pharmacist, United States Navy 357</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The new method of physical training in the United States Navy, by J. A.
Murphy, surgeon, United States Navy 368</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A study of the etiology of gangosa in Guam, by C. P. Kindleberger,
surgeon, United States Navy 381</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Unreliability of Wassermann tests using unheated serum, by E. R. Stitt,
medical inspector, and G. F. Clark, passed assistant surgeon, United States
Navy 410</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Laboratory note on antigens, by G. F. Clark, pasted assistant surgeon,
United States Navy 411</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Prevention of mouth infection, by Joseph Head, M. D., D. D. S 411</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Medical Department at general quarters and preparations for battle,
by A. Farenholt, surgeon, United States Navy 421</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A bacteriological index for dirt in milk, by J. J. Kinyoun, assistant
surgeon, Medical Reserve Corps, United States Navy 435</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Brief description of proposed plan of a fleet hospital ship, based upon
the type auxiliary hull, by E. M. Blackwell, surgeon, United States Navy.. 442</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The diagnostic value of the cutaneous tuberculin test in recruiting, by
E. M. Brown, passed assistant surgeon, United States Navy, retired 448</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 453</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A sanitary mess table for hospitals, by F. M. Bogan, surgeon, United
States Navy 455</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A suggested improvement of the Navy scuttle butt, by E. M. Blackwell,
surgeon, United States Navy 455</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Malaria cured by neosalvarsan, by F. M. Bogan, surgeon, United States
Navy 457</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of rupture of the bladder with fracture of the pelvis, by H. F.
Strine, surgeon, and M. E. Higgins, passed assistant surgeon, United States
Navy. 458</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical observations on the use of succinimid of mercury, by T. W.
Reed, passed assistant surgeon, United States Navy 459</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Points in the post-mortem ligation of the lingual artery, by O. J.
Mink, passed assistant surgeon, United States Navy 462</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Notes on the wounded at Vera Cruz, by H. F. Strine, surgeon, and M. E.
Higgins, passed assistant surgeon. United States Navy 464</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Case reports from the Naval Hospital, Portsmouth, N. H., by F. M.
Bogan, surgeon, United States Navy 469</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —The mouth in the etiology and symptomatology of
general systemic disturbances. Statistique m£dicale de la marine, 1909. By L.
W. Johnson. Antityphoid inoculation. Vaccines from the standpoint of the
physician. The treatment of sciatica. Chronic gastric ulcer and its relation to
gastric carcinoma. The nonprotein nitrogenous constituents of the blood in
chronic vascular nephritis<span>
</span>(arteriosclero-iis) as influenced by the level of protein metabolism.
The influence of diet on hepatic necrosis and toxicity of chloroform. The
rational treatment of tetanus. The comparative value of cardiac remedies. By A.
W. Dunbar and G. B. Crow </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Psychiatry. —Abderhalden's method. Precis de psychiatric Constitutional
immorality. Nine years' experience with manic-depressive insanity. The pupil
and its reflexes in insanity. By R. F. Sheehan.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. —On the occurrence of traumatic dislocations (luxationen) in
the Imperial German Navy during the last 20 years. By H. G. Beyer. The wounding
effects of the Turkish sharp-pointed bullet. By T. W. Richards. Intestinal
obstruction: formation and absorption of toxin. By G. B. Crow </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. —Relation of oysters to the transmission of
infectious diseases. The proper diet in the Tropics, with some pertinent remarks
on the use of alcohol. By E. W. Brown. Report of committee</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">upon period of isolation and exclusion from school in cases of
communicable disease. Resultats d'une enquete relative a la morbidity venerienne
dans la division navale d'Extreme-Orient et aux moyens susceptibles de la
restreindre. Ship's hygiene in the middle of the seventeenth century- Progress in
ship's hygiene during the nineteenth century. The origin of some of the
streptococci found in milk. On the further perfecting of mosquito spraying. By
C. N. Fiske and R. C. Ransdell</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — Le transport, colloidal de medicaments dans le cholera.
By T. W. Richards. Cholera in the Turkish Army. A supposed case of yellow fever
in Jamaica. By L. W. Johnson. Note on a new geographic locality for balantidiosis.
Brief note on Toxoplasma pyroqenes. Note on certain protozoalike bodies in a
case of protracted fever with splenomegaly. The emetine and other treatment of
amebic dysentery and hepatitis, including liver abscess. A study of epidemic dysentery
in the Fiji Islands. By E. R. Stitt</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. — The best method of staining
Treponema pallidum. By C. N. Fiske. Bacteriological methods of meat analysis.
By R. C. Ransdell. Primary tissue lesions in the heart produced by Spirochete
pallida. Ten tests by which a physician may determine when p patient is cured
of gonorrhea. Diagnostic value of percutaneous tuberculin test (Moro). Some
causes of failure of vaccine therapy. A method of increasing the accuracy and
delicacy of the Wassermann reaction: By A. B. Clifford and G. F. Clark</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. —Quantitative test of pancreatic function. A comparison
of various preservatives of urine. A clinical method for the rapid estimation
of the quantity of dextrose in urine. By E. W. Brown and O. G. Ruge</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. —Intraocular pressure. Strauma as an
important factor in diseases of the eye. Carbonic cauterization "in the
treatment of granular ophthalmia. Ocular and other complications of syphilis treated
by salvarsan. Some notes on hay fever. A radiographic study of the mastoid. Ear
complications during typhoid fever. Su di un caso di piccola sanguisuga
cavallina nel bronco destro e su 7 casi di grosse sanguisughe cavalline in
laringe in trachea e rino-faringe. By E. J. Grow and G. B. Trible</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters: </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">American medico-psychological association, by R. F. Sheehan, passed assistant
surgeon, United States Navy 517</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of 11 cases of asphyxiation from coal gas, by L. C. Whiteside,
passed assistant surgeon, United States Navy 522</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Extracts from annual sanitary reports for 1913 — United States Naval
Academy, Annapolis, Md., by A. M. D. McCormick, medical director, United States
Navy 523</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Arkansas, by W. B. Grove, surgeon, United States Navy 524 </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Marine barracks, Camp Elliott, Canal Zone, Panama, by B. H. Dorsey, passed
assistant surgeon, United States Navy 525</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Cincinnati, by J. B. Mears, passed assistant surgeon. United States
Navy 526</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Florida, by M. S. Elliott, surgeon, United States Navy 527</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Naval training station, Great Lakes, Ill., by J. S. Taylor, surgeon, United
States Navy 527</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Naval station, Guam, by C. P. Kindleberger, surgeon, United States Navy
528</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Naval Hospital, Las Animas, Colo., by G. H. Barber, medical inspector, United
States Navy 532</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Nebraska, by E. H. H. Old, passed assistant surgeon, United States
Navy 533</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. North Dakota, by J. C. Pryor, surgeon, United States Navy. .
534</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Navy yard, Olongapo, P. L, by J. S. Woodward, passed assistant surgeon,
United States Navy 536</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. San Francisco, by T. W. Reed, passed assistant surgeon, United
States Navy 537</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Saratoga, by H. R. Hermesch, assistant surgeon, United States Navy
538</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Scorpion, by E. P. Huff, passed assistant surgeon, United States
Navy 538</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. West Virginia, by O. J. Mink, passed assistant surgeon, United
States Navy 539</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 4</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface V</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some prevailing ideas regarding the treatment of tuberculosis, by
Passed Asst. Surg. G. B. Crow 541</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Training School for the Hospital Corps of the Navy, by Surg. F. E. McCullough
and Passed Asst. Surg. J. B. Kaufman 555</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Khaki dye for white uniforms, by Passed Asst. Surg. W. E. Eaton 561</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some facts and some fancies regarding the unity of yaws and syphilis,
by Surg. C. S. Butler 561</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Quinine prophylaxis of malaria, by Passed Asst. Surg. L. W. McGuire 571</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The nervous system and naval warfare, translated by Surg. T. W.
Richards. 576</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Measles, by Surg. G. F. Freeman 586</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Smallpox and vaccination, by Passed Asst. Surg. T. W. Raison 589</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Rabies; methods of diagnosis and immunization, by Passed Asst. Surg. F.
X. Koltes 597</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Syphilis aboard ship, by Passed Asst. Surg. G. F. Cottle 605</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Systematic recording and treatment of syphilis, by Surg. A. M.
Fauntleroy and Passed Asst. Surg. E. H. H. Old 620</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Organization and station bills of the U. S. naval hospital ship Solace,
by Surg. W. M. Garton 624</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 647</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthological collection 647</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Succinimid of mercury in pyorrhea alveolaris, by Acting Asst. Dental Surg.
P. G. White 649</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of pityriasis rosea, by Surg. R. E. Ledbetter 651</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Emetin in the treatment of amebic abscess of the liver, by Surg. H. F. Strine
and Passed Asst. Surg. L. Sheldon, jr 653 </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Salvarsan in a case of amebic dysentery, by Passed Asst. Surg. O. J.
Mink. . 653</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Laceration of the subclavian artery and complete severing of brachial plexus,
by Surg. H. C. Curl and Passed Asst. Surg. C. B. Camerer 654</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Malarial infection complicating splenectomy, by Surg. H. F. Strine 655</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of gastric hemorrhage; operative interference impossible, by
Passed Arst. Surg. G. E. Robertson 656</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Operation for strangulated hernia, by Passed Asst. Surg. W. S. Pugh 657</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of bronchiectasis with hypertrophic pulmonary osteoarthropathy,
by Passed Asst. Surg. L. C. Whiteside 658</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Systematic recording and treatment of syphilis 665</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences: <span> </span></p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —A note of three cases of enteric fever inoculated
during the incubation period. By T. W. Richards. The modern treatment of
chancroids. The treatment of burns. By W. E. Eaton. Experiments on the curative
value of the intraspinal administration of tetanus antitoxin. Hexamethylenamin.
<span> </span>Hexamethylenamin as an internal
antiseptic in other fluids of the body than urine. Lumbar puncture as a special
procedure for controlling headache in the course of infectious diseases.
Cardiospasm. Acromion auscultation; a new and delicate test in the early
diagnosis of incipient pulmonary tuberculosis.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Diabetes mellitus and its differentiation from alimentary glycosuria.
The complement fixation test in typhoid fever; its comparison with the
agglutination test and blood culture method. By C. B. Crow.. 671</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Mental and nervous diseases. —A voice sign in chorea. By G. B. Crow.
Wassermann reaction and its application to neurology. Epilepsy: a theory of
causation founded upon the clinical manifestations and the therapeutic and
pathological data. Salvarsanized serum (Swift-Ellis treatment) in syphilitic diseases
of the central nervous system. Mental manifestations in tumors of the brain.
Some of the broader issues of the psycho-analytic n movement. Mental disease
and defect in United States troops. By R. Sheehan 6S1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. — Infiltration anesthesia. War surgery. Tenoplasty; tendon transplantation;
tendon substitution; neuroplasty. Carcinoma of the male breast. Visceral
pleureotomy for chronic empyema. By A. M. Fauntleroy and E. H. H. Old 6S8</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. — Further experiences with the Berkefold filter
in the purifying of lead-contaminated water. By T. W. Richards. Experiments in
the destruction of fly larvae in horse manure. By A. B. Clifford. Investigation
relative to the life cycle, brooding, and tome practical moans of reducing the
multiplication of flies in camp. By W. E. Eaton, Humidity and heat stroke;
further observations on an<span> </span>analysis of
50 cases. By C. N. Fiske 693</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — The treatment of aneylostoma anemia. Latent dysentery
or dysentery carriers. Naphthalone for the destruction of mosquitoes. Emetin in
amebic dysentery. By E. R. Stitt 704</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —Meningitis by
injection of pyogenic microbes in the peripheral nerves. The growth of pathogenic
intestinal bacteria in bread. Present status of the complement fixation test in
the diagnosis of gonorrheal infections. Practical application of the luetin
test. By A. B. Clifford and G. F. Clark 707</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. — Misting of eyeglasses. By E. L. Sleeth.
The treatment of ocular syphilis by salvarsan and neo salvarsan. The moving
picture and the eye. Treatment of various forms of ocular syphilis with
salvarsan. Rapid, painless, and bloodless method for removing the inferior
turbinate. Hemorrhage from the superior petrosal sinus. The frequency of
laryngeal tuberculosis in Massachusetts.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Intrinsic cancer of larynx. Treatment of hematoma of the auricle. By E.
J. Grow and G. B. Trible 709</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Care of wounded at Mazatlan and at Villa Union, by Medical Inspector S.
G. Evans 713</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medico-military reports of the occupation of Vera Cruz 715</p>
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Ipê Amarelo, Tabebuia [chrysotricha or ochracea].
Ipê-amarelo em Brasília (UnB), Brasil.
This tree is in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Ipê Amarelo, Tabebuia [chrysotricha or ochracea].
Ipê-amarelo em Brasília, Brasil.
This tree is in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Les bactéries et leur rôle dans l'anatomie et l'histologie pathologiques des maladies infectieuses :
Paris :F. Alcan,1885.
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Lavender: benefits and general use
Lavender: benefits and general use
History – Lavender
Lavender and its uses were already known in ancient times. In ancient Egypt, she enjoyed great consideration and was used to make precious balms that were used especially to embalm the dead. The living used it as eau de toilette and put perfumed urns in the tomb of their dead. When excavations were discovered during Last home of Tutankhamen, it still smelled of lavender after 3000 years. As for the Greeks, they lavender flowers virgins they sacrificed to the gods. Lavender also became a very popular plant to eliminate bad smells. Therefore, in ancient times, prostitutes used lavender oil for bad breath.
Lavender was generally appreciated by all and when traveling monks worked poured the Alps in the 11th century and brought it to our country, it was not long to see fields lavender with blue and purple flowers all over Europe. Lavender became the plant of lovers who offered themselves small bouquets of lavender as a testimony of love. Women wore a dried sachet of dried lavender in the hope to attract the beloved, and in Ireland, a sachet of lavender was attached to the bride’s garter for that marriage succeeds. Lavender relieved many diseases and it was not long to use it also for flavoring delicacies.
Constance Isherwood advocated in 1900 that one puts “velvet dresses and precious furs” in lavender, whose smell would quickly chase moths Lavender soon became indispensable in everyday life. Its generic name Lavandula confirms it: it is derived from the Latin lavare – laver and refers to the importance that had once baths with lavender while highlighting the purifying action of lavender. Before synthetic fragrances and a multitude of penetrating perfume cleansers invaded us, he was current to put a few drops of lavender essence in the soapy water. Its fresh smell and life-giving off a peaceful and harmonious atmosphere in the room while protecting against pathogenic germs and insects of all kinds. This is how lavender has long been a remedy for a good woman very appreciated, which removes parasites such as lice, mites dress or food.
Botany and culture
Lavender is an odoriferous bushy shrub that belongs to the Lamiaceae family. His leaves are slender and gray-green in color. Depending on the variety, it reaches a height of 20 to approx. 90 cm. In the summer, it protects our gardens and delights us with its bright blue flowers pleasantly scented. There are many hybrids and forms of lavender cultivation. Note that true lavender (Lavandula angustifolia) is the variety that best resists the cold of winter. It grows well until an altitude of 1200 above sea level. His sister, the lavender aspic (Lavandula latifolia), which has silvery leaves a little wider and can reach a height of up to 90 cm, supports very well our climate. Unlike his close relative, lavender stechas (Lavandula stoechas), with large bracts purple to purple or white at the tips of the ears, and then other pinnate or toothed species (Lavandula dentata), which generally
not cold and must, therefore, be grown in pots or pans.
Lavender comes from Mediterranean regions and needs to grow well in a sunny place in the garden, where it will enchant us with its haunting smell. Small varieties give pretty borders of pleasantly scented beds, which must be cut regularly. We will do well to provide more space in the garden for varieties such as lavender aspic or lavandins (natural hybrids between Lav Angustifolia and Lav latifolia) that can grow to an impressive size.
Lavender is propagated by cuttings or sowing. During flowering, from July to August, butterflies and bees crowd around the lavender flowers – this magnificent show is a pleasure for all the senses that will delight the friends of nature. The harvest is done during flowering, we make with the flowers bouquets that we put to dry in a shady place and well ventilated. The plants are pruned after the summer bloom. This avoids an excessive lignification of the plant and promotes healthy and vital growth. We even attend a second abundant bloom.
Lavender, planted between roses, protects against aphids. The smell of lavender or more exactly its abundant essential oil has, in addition to the properties listed below, the faculty to inhibit the growth of fungi. That’s how lavender oil is used successfully on plants plagued by fungi or parasites. We spray as a preventive, all 2-5 days depending on the condition of the plants, water added with lavender oil (1 drop of gasoline for 1 liter of water).
Use in natural medicine
Natural medicine uses essentially true lavender. The flowers and the essence that we draw have a calming effect on the central nervous system. In external use, the main use is the essential oil of lavender while in internal use, it is primarily infusions of flowers. Over 200 different substances have been isolated from lavender essential oil. The essence of lavender has an antiseptic, disinfecting, healing, but also calming and harmonizing action on the body and the psyche. It is interesting to note that lavender can both refresh and warm, relax and stimulate. Lavender relieves strong headaches, migraines, and disorders of the menstruation. Overdose, however, may eventually cause their appearance. during the first world war, military doctors used lavender oil to disinfect wounds. In case of burns, compresses or a gentle rinse with lavender oil is beneficial and can significantly accelerate the healing process.
Lavender also enters in the composition of a large number of dyes, ointments, balms, massage oils, additives inhalations and other preparations which are used externally for treatment of eczema, insect bites and skin disorders the most diverse, to relieve gout flares and other rheumatic pains.
in case of lumbago and sprain, but also against diseases of the respiratory tract and of course also against bad breath. In internal use, lavender relieves, usually in the form of herbal tea, stomach pains, flatulence, nausea and disorders of digestion. On the psychic level, lavender is used in aromatherapy to fight disorders nervous and insomnia.
In a scented lamp or in the form of herbal tea, lavender promotes the relaxation, makes the mind clear and ready and gives the body and soul a sense of well-being and harmony. Use in the kitchen Lavender offers us a wide range of possibilities of use. Whether in medicine natural, as we have already seen, or in the field of cosmetics and perfumes. Intermedia species (see above) are frequently used for these applications, the yield of which is is four times larger. The essential oil that is extracted is commercially available under the name of lavender. We use the flowers and essence of Intermedia species, lavender aspic and of course, all the other varieties of lavender to make potpourri of flowers and perfumes, aromatic cushions or sachets of lavender, to perfume its interior or to add them to cleaning products and detergents of neutral odor.
In the kitchen, lavender is reborn. The kitchen and the decoration with the flowers of lavender are very fashionable. Their beauty and aroma are a delight for the eyes and the palate. The fresh flowers are candied or added to salads, jams, jellies or ice cream. Macerated in vinegar, they give a delicious herbal vinegar for a vinaigrette refined. Pastries and desserts flavored with lavender have a very delicate taste. Let yourself be inspired by the scent of lavender for new culinary experiences. Create a deliciously mousse perfumed with lavender flowers or make your own “biscuits of love” …
The virtues and uses of lavender and lavender essential oils
The perfumes
Lavender has particularly fine olfactory properties, delicate and complex, which make it an oil essential choice, especially for fine perfumery. Thus, the vast majority of male perfumes employs this raw material: For a man of Caron, Pure Lavender d’Azzaro, The Male of Jean-Paul Gauthier, Heritage of Guerlain, Old English Lavender of Yardley …
Medicinal products
Essential oils are widely used in pharmacy and in aromatherapy. Lavender has properties antiseptic, soothing and healing. Lavandin is recognized for its toning, relaxing and antiseptics.
Cosmetic products
In cosmetics, several brands develop ranges or lavender-based products, for its fresh scent and pleasant as well as for its virtues. We find her then as a perfuming agent for skin care products face, body or hair. Decorative products and room fragrances Lavender oil is found in decorative products and ambiance: scented candles, rotten pots, lamps perfumes, etc.
Cleaning products
Lavandin essential oil is mainly used by big manufacturers to scent soaps and detergents. Its scent gives a pleasant feeling of well-being, relaxation, and cleanliness.
Lavender in the kitchen
Lavender can also be used in cooking! It’s an original way to change the flavor of your dishes. You will make your guests enjoy all the benefits of this medicinal plant as its beneficial action on the intestinal transit or its diuretic and antispasmodic properties. Essential oils must be used with great care and dosages must be respected, even in the kitchen. The rule of thumb is to add one drop of essential oil per liter of cooking preparation. You can then adjust according to your tastes and your dishes! Add the essential oil at the end of cooking to preserve all its qualities. To add to your dish or sauce, dilute it in a little oil or honey if your preparation is sweet.
Lavender against Insects
Essential oil of Lavender combined with other essential oils can also allow you to create your own anti-insect sprays! Lavender, for example, becomes a weapon against wasps and horseflies when mixed with clove oil! It is, therefore, possible to create different synergy lavender based on the insects that we want to leave. Fleas, ticks, mosquitoes, mites, lice …
Anti-lice tip: If you fear that your child is bringing lice back to school, simply put a drop of lavender essential oil behind the neck or on the collar of his t-shirt and these little animals should not come and colonize his little head.
Against fleas and ticks: You can also spray the place where your dog sleeps with a mixture of lavender and water (or rubbing alcohol) to scare away fleas and ticks!
Warning for cat owners:
Be careful if you have a cat! Essential oils are toxic to these pets. They can not assimilate them in the same way as we do and, in the long run, risk suffering from liver poisoning.
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Maize (/meɪz/ MAYZ; Zea mays subsp. mays, from Spanish: maíz after Taino: mahiz), also known as corn (North American and Australian English), is a cereal grain first domesticated by indigenous peoples in southern Mexico about 10,000 years ago. The leafy stalk of the plant produces pollen inflorescences and separate ovuliferous inflorescences called ears that yield kernels or seeds, which are fruits.
Maize has become a staple food in many parts of the world, with the total production of maize surpassing that of wheat or rice. In addition to being consumed directly by humans (often in the form of masa), maize is also used for corn ethanol, animal feed and other maize products, such as corn starch and corn syrup. The six major types of maize are dent corn, flint corn, pod corn, popcorn, flour corn, and sweet corn. Sugar-rich varieties called sweet corn are usually grown for human consumption as kernels, while field corn varieties are used for animal feed, various corn-based human food uses (including grinding into cornmeal or masa, pressing into corn oil, and fermentation and distillation into alcoholic beverages like bourbon whiskey), and as chemical feedstocks. Maize is also used in making ethanol and other biofuels.
Maize is widely cultivated throughout the world, and a greater weight of maize is produced each year than any other grain. In 2014, total world production was 1.04 billion tonnes. Maize is the most widely grown grain crop throughout the Americas, with 361 million metric tons grown in the United States alone in 2014. Genetically modified maize made up 85% of the maize planted in the United States in 2009. Subsidies in the United States help to account for its high level of cultivation of maize and its position as the largest producer in the world.
HISTORY
PRE-COLUMBIAN DEVELOPMENT
Maize is a cultigen; human intervention is required for it to propagate. Whether or not the kernels fall off the cob on their own is a key piece of evidence used in archaeology to distinguish domesticated maize from its naturally-propagating teosinte ancestor. Genetic evidence can also be used to determine when various lineages split.
Most historians believe maize was domesticated in the Tehuacán Valley of Mexico. Recent research in the early 21st century has modified this view somewhat; scholars now indicate the adjacent Balsas River Valley of south-central Mexico as the center of domestication.
An influential 2002 study by Matsuoka et al. has demonstrated that, rather than the multiple independent domestications model, all maize arose from a single domestication in southern Mexico about 9,000 years ago. The study also demonstrated that the oldest surviving maize types are those of the Mexican highlands. Later, maize spread from this region over the Americas along two major paths. This is consistent with a model based on the archaeological record suggesting that maize diversified in the highlands of Mexico before spreading to the lowlands.
Archaeologist Dolores Piperno has said:
A large corpus of data indicates that [maize] was dispersed into lower Central America by 7600 BP [5600 BC] and had moved into the inter-Andean valleys of Colombia between 7000 and 6000 BP [5000–4000 BC].
— Dolores Piperno, The Origins of Plant Cultivation and Domestication in the New World Tropics: Patterns, Process, and New Developments
Since then, even earlier dates have been published.
According to a genetic study by Embrapa, corn cultivation was introduced in South America from Mexico, in two great waves: the first, more than 6000 years ago, spread through the Andes. Evidence of cultivation in Peru has been found dating to about 6700 years ago. The second wave, about 2000 years ago, through the lowlands of South America.
The earliest maize plants grew only small, 25-millimetre-long (1 in) corn cobs, and only one per plant. In Jackson Spielvogel's view, many centuries of artificial selection (rather than the current view that maize was exploited by interplanting with teosinte) by the indigenous people of the Americas resulted in the development of maize plants capable of growing several cobs per plant, which were usually several centimetres/inches long each. The Olmec and Maya cultivated maize in numerous varieties throughout Mesoamerica; they cooked, ground and processed it through nixtamalization. It was believed that beginning about 2500 BC, the crop spread through much of the Americas. Research of the 21st century has established even earlier dates. The region developed a trade network based on surplus and varieties of maize crops.
Mapuches of south-central Chile cultivated maize along with quinoa and potatoes in pre-Hispanic times; however, potato was the staple food of most Mapuches, "specially in the southern and coastal [Mapuche] territories where maize did not reach maturity". Before the expansion of the Inca Empire maize was traded and transported as far south as 40°19' S in Melinquina, Lácar Department. In that location maize remains were found inside pottery dated to 730 ± 80 BP and 920 ± 60 BP. Probably this maize was brought across the Andes from Chile. The presence of maize in Guaitecas Archipelago (43°55' S), the southernmost outpost of pre-Hispanic agriculture, is reported by early Spanish explorers. However the Spanish may have misidentified the plant.
COLUMBIAN EXCHANGE
After the arrival of Europeans in 1492, Spanish settlers consumed maize, and explorers and traders carried it back to Europe and introduced it to other countries. Spanish settlers far preferred wheat bread to maize, cassava, or potatoes. Maize flour could not be substituted for wheat for communion bread, since in Christian belief only wheat could undergo transubstantiation and be transformed into the body of Christ. Some Spaniards worried that by eating indigenous foods, which they did not consider nutritious, they would weaken and risk turning into Indians. "In the view of Europeans, it was the food they ate, even more than the environment in which they lived, that gave Amerindians and Spaniards both their distinctive physical characteristics and their characteristic personalities." Despite these worries, Spaniards did consume maize. Archeological evidence from Florida sites indicate they cultivated it as well.
Maize spread to the rest of the world because of its ability to grow in diverse climates. It was cultivated in Spain just a few decades after Columbus's voyages and then spread to Italy, West Africa and elsewhere. Widespread cultivation most likely began in southern Spain in 1525, after which it quickly spread to the rest of the Spanish Empire including its territories in Italy (and, from there, to other Italian states). Maize had many advantages over wheat and barley; it yielded two and a half times the food energy per unit cultivated area, could be harvested in successive years from the same plot of land, and grew in wildly varying altitudes and climates, from relatively dry regions with only 250 mm (10 in) of annual rainfall to damp regions with over 5,000 mm (200 in). By the 17th century it was a common peasant food in Southwestern Europe, including Portugal, Spain, southern France, and Italy. By the 18th century, it was the chief food of the southern French and Italian peasantry, especially in the form of polenta in Italy.
Names
The word maize derives from the Spanish form of the indigenous Taíno word for the plant, mahiz. It is known by other names around the world.
The word "corn" outside the US, Canada, Australia, and New Zealand refers to any cereal crop, its meaning understood to vary geographically to refer to the local staple. In the United States, Canada, Australia, and New Zealand, corn primarily means maize; this usage started as a shortening of "Indian corn". "Indian corn" primarily means maize (the staple grain of indigenous Americans), but can refer more specifically to multicolored "flint corn" used for decoration.
In places outside the US, Canada, Australia, and New Zealand, corn often refers to maize in culinary contexts. The narrower meaning is usually indicated by some additional word, as in sweet corn, sweetcorn, corn on the cob, baby corn, the puffed confection known as popcorn and the breakfast cereal known as corn flakes.
In Southern Africa, maize is commonly called mielie (Afrikaans) or mealie (English), words derived from the Portuguese word for maize, milho.
Maize is preferred in formal, scientific, and international usage because it refers specifically to this one grain, unlike corn, which has a complex variety of meanings that vary by context and geographic region. Maize is used by agricultural bodies and research institutes such as the FAO and CSIRO. National agricultural and industry associations often include the word maize in their name even in English-speaking countries where the local, informal word is something other than maize; for example, the Maize Association of Australia, the Indian Maize Development Association, the Kenya Maize Consortium and Maize Breeders Network, the National Maize Association of Nigeria, the Zimbabwe Seed Maize Association.
STRUCTURE AND PHYSIOLOGY
The maize plant is often 3 m (10 ft) in height, though some natural strains can grow 13 m (43 ft). The stem is commonly composed of 20 internodes of 18 cm (7 in) length. The leaves arise from the nodes, alternately on opposite sides on the stalk. A leaf, which grows from each node, is generally 9 cm (3+1⁄2 in) in width and 120 cm (3 ft 11 in) in length.
Ears develop above a few of the leaves in the midsection of the plant, between the stem and leaf sheath, elongating by around 3 mm (1⁄8 in) per day, to a length of 18 cm (7 in) with 60 cm (24 in) being the maximum alleged in the subspecies. They are female inflorescences, tightly enveloped by several layers of ear leaves commonly called husks. Certain varieties of maize have been bred to produce many additional developed ears. These are the source of the "baby corn" used as a vegetable in Asian cuisine.
The apex of the stem ends in the tassel, an inflorescence of male flowers. When the tassel is mature and conditions are suitably warm and dry, anthers on the tassel dehisce and release pollen. Maize pollen is anemophilous (dispersed by wind), and because of its large settling velocity, most pollen falls within a few meters of the tassel.
Elongated stigmas, called silks, emerge from the whorl of husk leaves at the end of the ear. They are often pale yellow and 18 cm (7 in) in length, like tufts of hair in appearance. At the end of each is a carpel, which may develop into a "kernel" if fertilized by a pollen grain. The pericarp of the fruit is fused with the seed coat referred to as "caryopsis", typical of the grasses, and the entire kernel is often referred to as the "seed". The cob is close to a multiple fruit in structure, except that the individual fruits (the kernels) never fuse into a single mass. The grains are about the size of peas, and adhere in regular rows around a white, pithy substance, which forms the ear. The maximum size of kernels is reputedly 2.5 cm (1 in). An ear commonly holds 600 kernels. They are of various colors: blackish, bluish-gray, purple, green, red, white and yellow. When ground into flour, maize yields more flour with much less bran than wheat does. It lacks the protein gluten of wheat and, therefore, makes baked goods with poor rising capability. A genetic variant that accumulates more sugar and less starch in the ear is consumed as a vegetable and is called sweet corn. Young ears can be consumed raw, with the cob and silk, but as the plant matures (usually during the summer months), the cob becomes tougher and the silk dries to inedibility. By the end of the growing season, the kernels dry out and become difficult to chew without cooking them tender first in boiling water.
Planting density affects multiple aspects of maize. Modern farming techniques in developed countries usually rely on dense planting, which produces one ear per stalk. Stands of silage maize are yet denser,[citation needed] and achieve a lower percentage of ears and more plant matter.
Maize is a facultative short-day plant and flowers in a certain number of growing degree days > 10 °C (50 °F) in the environment to which it is adapted. The magnitude of the influence that long nights have on the number of days that must pass before maize flowers is genetically prescribed and regulated by the phytochrome system.
Photoperiodicity can be eccentric in tropical cultivars such that the long days characteristic of higher latitudes allow the plants to grow so tall that they do not have enough time to produce seed before being killed by frost. These attributes, however, may prove useful in using tropical maize for biofuels.
Immature maize shoots accumulate a powerful antibiotic substance, 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA). DIMBOA is a member of a group of hydroxamic acids (also known as benzoxazinoids) that serve as a natural defense against a wide range of pests, including insects, pathogenic fungi and bacteria. DIMBOA is also found in related grasses, particularly wheat. A maize mutant (bx) lacking DIMBOA is highly susceptible to attack by aphids and fungi. DIMBOA is also responsible for the relative resistance of immature maize to the European corn borer (family Crambidae). As maize matures, DIMBOA levels and resistance to the corn borer decline.
Because of its shallow roots, maize is susceptible to droughts, intolerant of nutrient-deficient soils, and prone to be uprooted by severe winds.
While yellow maizes derive their color from lutein and zeaxanthin, in red-colored maizes, the kernel coloration is due to anthocyanins and phlobaphenes. These latter substances are synthesized in the flavonoids synthetic pathway from polymerization of flavan-4-ols by the expression of maize pericarp color1 (p1) gene which encodes an R2R3 myb-like transcriptional activator of the A1 gene encoding for the dihydroflavonol 4-reductase (reducing dihydroflavonols into flavan-4-ols) while another gene (Suppressor of Pericarp Pigmentation 1 or SPP1) acts as a suppressor. The p1 gene encodes an Myb-homologous transcriptional activator of genes required for biosynthesis of red phlobaphene pigments, while the P1-wr allele specifies colorless kernel pericarp and red cobs, and unstable factor for orange1 (Ufo1) modifies P1-wr expression to confer pigmentation in kernel pericarp, as well as vegetative tissues, which normally do not accumulate significant amounts of phlobaphene pigments. The maize P gene encodes a Myb homolog that recognizes the sequence CCT/AACC, in sharp contrast with the C/TAACGG bound by vertebrate Myb proteins.
The ear leaf is the leaf most closely associated with a particular developing ear. This leaf and above contribute 70% to 75% to 90% of grain fill. Therefore fungicide application is most important in that region in most disease environments.
ABNORMAL FLOWERS
Maize flowers may sometimes exhibit mutations that lead to the formation of female flowers in the tassel. These mutations, ts4 and Ts6, prohibit the development of the stamen while simultaneously promoting pistil development. This may cause inflorescences containing both male and female flowers, or hermaphrodite flowers.
GENETICS
Maize is an annual grass in the family Gramineae, which includes such plants as wheat, rye, barley, rice, sorghum, and sugarcane. There are two major species of the genus Zea (out of six total): Zea mays (maize) and Zea diploperennis, which is a perennial type of teosinte. The annual teosinte variety called Zea mays mexicana is the closest botanical relative to maize. It still grows in the wild as an annual in Mexico and Guatemala.
Many forms of maize are used for food, sometimes classified as various subspecies related to the amount of starch each has:
Flour corn: Zea mays var. amylacea
Popcorn: Zea mays var. everta
Dent corn : Zea mays var. indentata
Flint corn: Zea mays var. indurata
Sweet corn: Zea mays var. saccharata and Zea mays var. rugosa
Waxy corn: Zea mays var. ceratina
Amylomaize: Zea mays
Pod corn: Zea mays var. tunicata Larrañaga ex A. St. Hil.
Striped maize: Zea mays var. japonica
This system has been replaced (though not entirely displaced) over the last 60 years by multivariable classifications based on ever more data. Agronomic data were supplemented by botanical traits for a robust initial classification, then genetic, cytological, protein and DNA evidence was added. Now, the categories are forms (little used), races, racial complexes, and recently branches.
Maize is a diploid with 20 chromosomes (n=10). The combined length of the chromosomes is 1500 cM. Some of the maize chromosomes have what are known as "chromosomal knobs": highly repetitive heterochromatic domains that stain darkly. Individual knobs are polymorphic among strains of both maize and teosinte.
Barbara McClintock used these knob markers to validate her transposon theory of "jumping genes", for which she won the 1983 Nobel Prize in Physiology or Medicine. Maize is still an important model organism for genetics and developmental biology today.
The centromeres have two types of structural components, both of which are found only in the centromeres: Large arrays of CentC, a short satellite DNA; and a few of a family of retrotransposons. The B chromosome, unlike the others, contains an additional repeat which extends into neighboring areas of the chromosome. Centromeres can accidentally shrink during division and still function, although it is thought this will fail if it shrinks below a few hundred kilobase. Kinetochores contain RNA originating from centromeres. Centromere regions can become inactive, and can continue in that state if the chromosome still has another active one.
The Maize Genetics Cooperation Stock Center, funded by the USDA Agricultural Research Service and located in the Department of Crop Sciences at the University of Illinois at Urbana-Champaign, is a stock center of maize mutants. The total collection has nearly 80,000 samples. The bulk of the collection consists of several hundred named genes, plus additional gene combinations and other heritable variants. There are about 1000 chromosomal aberrations (e.g., translocations and inversions) and stocks with abnormal chromosome numbers (e.g., tetraploids). Genetic data describing the maize mutant stocks as well as myriad other data about maize genetics can be accessed at MaizeGDB, the Maize Genetics and Genomics Database.
In 2005, the US National Science Foundation (NSF), Department of Agriculture (USDA) and the Department of Energy (DOE) formed a consortium to sequence the B73 maize genome. The resulting DNA sequence data was deposited immediately into GenBank, a public repository for genome-sequence data. Sequences and genome annotations have also been made available throughout the project's lifetime at the project's official site.
Primary sequencing of the maize genome was completed in 2008. On November 20, 2009, the consortium published results of its sequencing effort in Science. The genome, 85% of which is composed of transposons, was found to contain 32,540 genes (By comparison, the human genome contains about 2.9 billion bases and 26,000 genes). Much of the maize genome has been duplicated and reshuffled by helitrons—group of rolling circle transposons.
In Z. mays and various other angiosperms the MADS-box motif is involved in floral development. Early study in several angiosperm models including Z. mays was the beginning of research into the molecular evolution of floral structure in general, as well as their role in nonflowering plants.
EVOLUTION
As with many plants and animals, Z. mays has a positive correlation between effective population size and the magnitude of selection pressure. Z. m. having an EPS of ~650,000, it clusters with others of about the same EPS, and has 79% of its amino acid sites under selection.
Recombination is a significant source of diversity in Z. mays. (Note that this finding supersedes previous studies which showed no such correlation.)
This recombination/diversity effect is seen throughout plants but is also found to not occur – or not as strongly – in regions of high gene density. This is likely the reason that domesticated Z. mays has not seen as much of an increase in diversity within areas of higher density as in regions of lower density, although there is more evidence in other plants.
Some lines of maize have undergone ancient polyploidy events, starting 11m years ago. Over that time ~72% of polyploid duplicated genes have been retained, which is higher than other plants with older polyploidy events. Thus maize may be due to lose more duplicate genes as time goes along, similar to the course followed by the genomes of other plants. If so - if gene loss has merely not occurred yet - that could explain the lack of observed positive selection and lower negative selection which are observed in otherwise similar plants, i.e. also naturally outcrossing and with similar effective population sizes.
Ploidy does not appear to influence EPS or magnitude of selection effect in maize.
BREEDING
Maize reproduces sexually each year. This randomly selects half the genes from a given plant to propagate to the next generation, meaning that desirable traits found in the crop (like high yield or good nutrition) can be lost in subsequent generations unless certain techniques are used.
Maize breeding in prehistory resulted in large plants producing large ears. Modern breeding began with individuals who selected highly productive varieties in their fields and then sold seed to other farmers. James L. Reid was one of the earliest and most successful developing Reid's Yellow Dent in the 1860s. These early efforts were based on mass selection. Later breeding efforts included ear to row selection (C. G. Hopkins c. 1896), hybrids made from selected inbred lines (G. H. Shull, 1909), and the highly successful double cross hybrids using four inbred lines (D. F. Jones c. 1918, 1922). University supported breeding programs were especially important in developing and introducing modern hybrids. By the 1930s, companies such as Pioneer devoted to production of hybrid maize had begun to influence long-term development. Internationally important seed banks such as the International Maize and Wheat Improvement Center (CIMMYT) and the US bank at the Maize Genetics Cooperation Stock Center University of Illinois at Urbana-Champaign maintain germplasm important for future crop development.
Since the 1940s the best strains of maize have been first-generation hybrids made from inbred strains that have been optimized for specific traits, such as yield, nutrition, drought, pest and disease tolerance. Both conventional cross-breeding and genetic modification have succeeded in increasing output and reducing the need for cropland, pesticides, water and fertilizer. There is conflicting evidence to support the hypothesis that maize yield potential has increased over the past few decades. This suggests that changes in yield potential are associated with leaf angle, lodging resistance, tolerance of high plant density, disease/pest tolerance, and other agronomic traits rather than increase of yield potential per individual plant.
Tropical landraces remain an important and underutilized source of resistance alleles for for disease and for herbivores. Notable discoveries of rare alleles for this purpose were made by Dao et al 2014 and Sood et al 2014.
GLOBAL PROGRAM
CIMMYT operates a conventional breeding program to provide optimized strains. The program began in the 1980s. Hybrid seeds are distributed in Africa by the Drought Tolerant Maize for Africa project.
GENETIC MODIFICATION
Genetically modified (GM) maize was one of the 26 GM crops grown commercially in 2016. The vast majority of this is Bt maize. Grown since 1997 in the United States and Canada, 92% of the US maize crop was genetically modified in 2016 and 33% of the worldwide maize crop was GM in 2016. As of 2011, Herbicide-tolerant maize varieties were grown in Argentina, Australia, Brazil, Canada, China, Colombia, El Salvador, the European Union, Honduras, Japan, Korea, Malaysia, Mexico, New Zealand, Philippines, the Russian Federation, Singapore, South Africa, Taiwan, Thailand, and the United States. Insect-resistant maize was grown in Argentina, Australia, Brazil, Canada, Chile, China, Colombia, Egypt, the European Union, Honduras, Japan, Korea, Malaysia, Mexico, New Zealand, Philippines, South Africa, Switzerland, Taiwan, the United States, and Uruguay.
In September 2000, up to $50 million worth of food products were recalled due to the presence of Starlink genetically modified corn, which had been approved only for animal consumption and had not been approved for human consumption, and was subsequently withdrawn from the market.
ORIGIN
Maize is the domesticated variant of teosinte. The two plants have dissimilar appearance, maize having a single tall stalk with multiple leaves and teosinte being a short, bushy plant. The difference between the two is largely controlled by differences in just two genes, called grassy tillers-1 (gt1, A0A317YEZ1) and teosinte branched-1 (tb1, Q93WI2).
Several theories had been proposed about the specific origin of maize in Mesoamerica:
It is a direct domestication of a Mexican annual teosinte, Zea mays ssp. parviglumis, native to the Balsas River valley in south-eastern Mexico, with up to 12% of its genetic material obtained from Zea mays ssp. mexicana through introgression.
It has been derived from hybridization between a small domesticated maize (a slightly changed form of a wild maize) and a teosinte of section Luxuriantes, either Z. luxurians or Z. diploperennis.
It has undergone two or more domestications either of a wild maize or of a teosinte. (The term "teosinte" describes all species and subspecies in the genus Zea, excluding Zea mays ssp. mays.)
It has evolved from a hybridization of Z. diploperennis by Tripsacum dactyloides.
In the late 1930s, Paul Mangelsdorf suggested that domesticated maize was the result of a hybridization event between an unknown wild maize and a species of Tripsacum, a related genus. This theory about the origin of maize has been refuted by modern genetic testing, which refutes Mangelsdorf's model and the fourth listed above.
The teosinte origin theory was proposed by the Russian botanist Nikolai Ivanovich Vavilov in 1931 and the later American Nobel Prize-winner George Beadle in 1932.: 10 It is supported experimentally and by recent studies of the plants' genomes. Teosinte and maize can cross-breed and produce fertile offspring. A number of questions remain concerning the species, among them:
how the immense diversity of the species of sect. Zea originated,
how the tiny archaeological specimens of 3500–2700 BC could have been selected from a teosinte, and
how domestication could have proceeded without leaving remains of teosinte or maize with teosintoid traits earlier than the earliest known until recently, dating from ca. 1100 BC.
The domestication of maize is of particular interest to researchers—archaeologists, geneticists, ethnobotanists, geographers, etc. The process is thought by some to have started 7,500 to 12,000 years ago. Research from the 1950s to 1970s originally focused on the hypothesis that maize domestication occurred in the highlands between the states of Oaxaca and Jalisco, because the oldest archaeological remains of maize known at the time were found there.
Connection with 'parviglumis' subspecies
Genetic studies, published in 2004 by John Doebley, identified Zea mays ssp. parviglumis, native to the Balsas River valley in Mexico's southwestern highlands, and also known as Balsas teosinte, as being the crop wild relative that is genetically most similar to modern maize. This was confirmed by further studies, which refined this hypothesis somewhat. Archaeobotanical studies, published in 2009, point to the middle part of the Balsas River valley as the likely location of early domestication; this river is not very long, so these locations are not very distant. Stone milling tools with maize residue have been found in an 8,700 year old layer of deposits in a cave not far from Iguala, Guerrero.
Doebley was part of the team that first published, in 2002, that maize had been domesticated only once, about 9,000 years ago, and then spread throughout the Americas.
A primitive corn was being grown in southern Mexico, Central America, and northern South America 7,000 years ago. Archaeological remains of early maize ears, found at Guila Naquitz Cave in the Oaxaca Valley, date back roughly 6,250 years; the oldest ears from caves near Tehuacan, Puebla, 5,450 B.P.
Maize pollen dated to 7,300 B.P. from San Andres, Tabasco, on the Caribbean coast has also been recovered.
As maize was introduced to new cultures, new uses were developed and new varieties selected to better serve in those preparations. Maize was the staple food, or a major staple – along with squash, Andean region potato, quinoa, beans, and amaranth – of most pre-Columbian North American, Mesoamerican, South American, and Caribbean cultures. The Mesoamerican civilization, in particular, was deeply interrelated with maize. Its traditions and rituals involved all aspects of maize cultivation – from the planting to the food preparation. Maize formed the Mesoamerican people's identity.
It is unknown what precipitated its domestication, because the edible portion of the wild variety is too small, and hard to obtain, to be eaten directly, as each kernel is enclosed in a very hard bivalve shell.
In 1939, George Beadle demonstrated that the kernels of teosinte are readily "popped" for human consumption, like modern popcorn. Some have argued it would have taken too many generations of selective breeding to produce large, compressed ears for efficient cultivation. However, studies of the hybrids readily made by intercrossing teosinte and modern maize suggest this objection is not well founded.
SPREADING TO THE NORTH
Around 4,500 ago, maize began to spread to the north; it was first cultivated in what is now the United States at several sites in New Mexico and Arizona, about 4,100 ago.
During the first millennium AD, maize cultivation spread more widely in the areas north. In particular, the large-scale adoption of maize agriculture and consumption in eastern North America took place about A.D. 900. Native Americans cleared large forest and grassland areas for the new crop.
In 2005, research by the USDA Forest Service suggested that the rise in maize cultivation 500 to 1,000 years ago in what is now the southeastern United States corresponded with a decline of freshwater mussels, which are very sensitive to environmental changes.
CULTIVATION
PLANTING
Because it is cold-intolerant, in the temperate zones maize must be planted in the spring. Its root system is generally shallow, so the plant is dependent on soil moisture. As a plant that uses C4 carbon fixation, maize is a considerably more water-efficient crop than plants that use C3 carbon fixation such as alfalfa and soybeans. Maize is most sensitive to drought at the time of silk emergence, when the flowers are ready for pollination. In the United States, a good harvest was traditionally predicted if the maize was "knee-high by the Fourth of July", although modern hybrids generally exceed this growth rate. Maize used for silage is harvested while the plant is green and the fruit immature. Sweet corn is harvested in the "milk stage", after pollination but before starch has formed, between late summer and early to mid-autumn. Field maize is left in the field until very late in the autumn to thoroughly dry the grain, and may, in fact, sometimes not be harvested until winter or even early spring. The importance of sufficient soil moisture is shown in many parts of Africa, where periodic drought regularly causes maize crop failure and consequent famine. Although it is grown mainly in wet, hot climates, it has been said to thrive in cold, hot, dry or wet conditions, meaning that it is an extremely versatile crop.
Maize was planted by the Native Americans in hills, in a complex system known to some as the Three Sisters. Maize provided support for beans, and the beans provided nitrogen derived from nitrogen-fixing rhizobia bacteria which live on the roots of beans and other legumes; and squashes provided ground cover to stop weeds and inhibit evaporation by providing shade over the soil. This method was replaced by single species hill planting where each hill 60–120 cm (2 ft 0 in–3 ft 11 in) apart was planted with three or four seeds, a method still used by home gardeners. A later technique was "checked maize", where hills were placed
1 m (40 in) apart in each direction, allowing cultivators to run through the field in two directions. In more arid lands, this was altered and seeds were planted in the bottom of 10–12 cm (4–4+1⁄2 in) deep furrows to collect water. Modern technique plants maize in rows which allows for cultivation while the plant is young, although the hill technique is still used in the maize fields of some Native American reservations. When maize is planted in rows, it also allows for planting of other crops between these rows to make more efficient use of land space.
In most regions today, maize grown in residential gardens is still often planted manually with a hoe, whereas maize grown commercially is no longer planted manually but rather is planted with a planter. In North America, fields are often planted in a two-crop rotation with a nitrogen-fixing crop, often alfalfa in cooler climates and soybeans in regions with longer summers. Sometimes a third crop, winter wheat, is added to the rotation.
Many of the maize varieties grown in the United States and Canada are hybrids. Often the varieties have been genetically modified to tolerate glyphosate or to provide protection against natural pests. Glyphosate is an herbicide which kills all plants except those with genetic tolerance. This genetic tolerance is very rarely found in nature.
In the midwestern United States, low-till or no-till farming techniques are usually used. In low-till, fields are covered once, maybe twice, with a tillage implement either ahead of crop planting or after the previous harvest. The fields are planted and fertilized. Weeds are controlled through the use of herbicides, and no cultivation tillage is done during the growing season. This technique reduces moisture evaporation from the soil, and thus provides more moisture for the crop. The technologies mentioned in the previous paragraph enable low-till and no-till farming. Weeds compete with the crop for moisture and nutrients, making them undesirable.
HARVESTING
Before the 20th century, all maize harvesting was by manual labour, by grazing, or by some combination of those. Whether the ears were hand-picked and the stover was grazed, or the whole plant was cut, gathered, and shocked, people and livestock did all the work. Between the 1890s and the 1970s, the technology of maize harvesting expanded greatly. Today, all such technologies, from entirely manual harvesting to entirely mechanized, are still in use to some degree, as appropriate to each farm's needs, although the thoroughly mechanized versions predominate, as they offer the lowest unit costs when scaled to large farm operations. For small farms, their unit cost can be too high, as their higher fixed cost cannot be amortized over as many units.[citation needed]
Before World War II, most maize in North America was harvested by hand. This involved a large number of workers and associated social events (husking or shucking bees). From the 1890s onward, some machinery became available to partially mechanize the processes, such as one- and two-row mechanical pickers (picking the ear, leaving the stover) and corn binders, which are reaper-binders designed specifically for maize (for example, Video on YouTube). The latter produce sheaves that can be shocked. By hand or mechanical picker, the entire ear is harvested, which then requires a separate operation of a maize sheller to remove the kernels from the ear. Whole ears of maize were often stored in corn cribs, and these whole ears are a sufficient form for some livestock feeding use. Today corn cribs with whole ears, and corn binders, are less common because most modern farms harvest the grain from the field with a combine and store it in bins. The combine with a corn head (with points and snap rolls instead of a reel) does not cut the stalk; it simply pulls the stalk down. The stalk continues downward and is crumpled into a mangled pile on the ground, where it usually is left to become organic matter for the soil. The ear of maize is too large to pass between slots in a plate as the snap rolls pull the stalk away, leaving only the ear and husk to enter the machinery. The combine separates the husk and the cob, keeping only the kernels.
When maize is a silage crop, the entire plant is usually chopped at once with a forage harvester (chopper) and ensiled in silos or polymer wrappers. Ensiling of sheaves cut by a corn binder was formerly common in some regions but has become uncommon. For storing grain in bins, the moisture of the grain must be sufficiently low to avoid spoiling. If the moisture content of the harvested grain is too high, grain dryers are used to reduce the moisture content by blowing heated air through the grain. This can require large amounts of energy in the form of combustible gases (propane or natural gas) and electricity to power the blowers.
PRODUCTION
Maize is widely cultivated throughout the world, and a greater weight of maize is produced each year than any other grain. In 2018, total world production was 1.15 billion tonnes, led by the United States with 34.2% of the total (table). China produced 22.4% of the global total.
UNITED STATES
In 2016, maize production was forecast to be over 380 million metric tons (15 billion bushels), an increase of 11% over 2014 American production. Based on conditions as of August 2016, the expected yield would be the highest ever for the United States. The area of harvested maize was forecast to be 35 million hectares (87 million acres), an increase of 7% over 2015. Maize is especially popular in Midwestern states such as Indiana, Iowa, and Illinois; in the latter, it was named the state's official grain in 2017.
STORAGE
Drying is vital to prevent or at least reduce mycotoxin contamination. Aspergillus and Fusarium spp. are the most common mycotoxin sources, but there are others. Altogether maize contaminants are so common, and this crop is so economically important, that maize mycotoxins are among the most important in agriculture in general.
USES
HUMAN FOOD
Maize and cornmeal (ground dried maize) constitute a staple food in many regions of the world. Maize is used to produce cornstarch, a common ingredient in home cooking and many industrialized food products. Maize starch can be hydrolyzed and enzymatically treated to produce syrups, particularly high fructose corn syrup, a sweetener; and also fermented and distilled to produce grain alcohol. Grain alcohol from maize is traditionally the source of Bourbon whiskey. Corn flour is used to make cornbread and other baked products.
In prehistoric times Mesoamerican women used a metate to process maize into ground cornmeal, allowing the preparation of foods that were more calorie dense than popcorn. After ceramic vessels were invented the Olmec people began to cook maize together with beans, improving the nutritional value of the staple meal. Although maize naturally contains niacin, an important nutrient, it was not bioavailable without the process of nixtamalization. The Maya used nixtamal meal to make varieties of porridges and tamales. The process was later used in the cuisine of the American South to prepare corn for grits and hominy.
Maize is a staple of Mexican cuisine. Masa (cornmeal treated with limewater) is the main ingredient for tortillas, atole and many other dishes of Central American food. It is the main ingredient of corn tortilla, tamales, pozole, atole and all the dishes based on them, like tacos, quesadillas, chilaquiles, enchiladas, tostadas and many more. In Mexico the fungus of maize, known as huitlacoche, is considered a delicacy.
Coarse maize meal is made into a thick porridge in many cultures: from the polenta of Italy, the angu of Brazil, the mămăligă of Romania, to cornmeal mush in the US (or hominy grits in the South) or the food called mieliepap in South Africa and sadza, nshima, ugali and other names in other parts of Africa. Introduced into Africa by the Portuguese in the 16th century, maize has become Africa's most important staple food crop. These are commonly eaten in the Southeastern United States, foods handed down from Native Americans, who called the dish sagamite.
Maize can also be harvested and consumed in the unripe state, when the kernels are fully grown but still soft. Unripe maize must usually be cooked to become palatable; this may be done by simply boiling or roasting the whole ears and eating the kernels right off the cob. Sweet corn, a genetic variety that is high in sugars and low in starch, is usually consumed in the unripe state. Such corn on the cob is a common dish in the United States, Canada, United Kingdom, Cyprus, some parts of South America, and the Balkans, but virtually unheard of in some European countries. Corn on the cob was hawked on the streets of early 19th-century New York City by poor, barefoot "Hot Corn Girls", who were thus the precursors of hot dog carts, churro wagons, and fruit stands seen on the streets of big cities today.
Within the United States, the usage of maize for human consumption constitutes only around 1/40th of the amount grown in the country. In the United States and Canada, maize is mostly grown to feed livestock, as forage, silage (made by fermentation of chopped green cornstalks), or grain. Maize meal is also a significant ingredient of some commercial animal food products.
NUTRITIONAL VALUE
Raw, yellow, sweet maize kernels are composed of 76% water, 19% carbohydrates, 3% protein, and 1% fat (table). In a 100-gram serving, maize kernels provide 86 calories and are a good source (10–19% of the Daily Value) of the B vitamins, thiamin, niacin (but see Pellagra warning below), pantothenic acid (B5) and folate (right table for raw, uncooked kernels, USDA Nutrient Database). In moderate amounts, they also supply dietary fiber and the essential minerals, magnesium and phosphorus whereas other nutrients are in low amounts (table).
Maize has suboptimal amounts of the essential amino acids tryptophan and lysine, which accounts for its lower status as a protein source. However, the proteins of beans and legumes complement those of maize.
FEED AND FODDER FOR LIVESTOCK
Maize is a major source of both grain feed and fodder for livestock. It is fed to the livestock in various ways. When it is used as a grain crop, the dried kernels are used as feed. They are often kept on the cob for storage in a corn crib, or they may be shelled off for storage in a grain bin. The farm that consumes the feed may produce it, purchase it on the market, or some of both. When the grain is used for feed, the rest of the plant (the corn stover) can be used later as fodder, bedding (litter), or soil amendment. When the whole maize plant (grain plus stalks and leaves) is used for fodder, it is usually chopped all at once and ensilaged, as digestibility and palatability are higher in the ensilaged form than in the dried form. Maize silage is one of the most valuable forages for ruminants. Before the advent of widespread ensilaging, it was traditional to gather the corn into shocks after harvesting, where it dried further. With or without a subsequent move to the cover of a barn, it was then stored for weeks to several months until fed to the livestock. Today ensilaging can occur not only in siloes but also in silage wrappers. However, in the tropics, maize can be harvested year-round and fed as green forage to the animals.
CHEMICALS
Starch from maize can also be made into plastics, fabrics, adhesives, and many other chemical products.
The corn steep liquor, a plentiful watery byproduct of maize wet milling process, is widely used in the biochemical industry and research as a culture medium to grow many kinds of microorganisms.
Chrysanthemin is found in purple corn and is used as a food coloring.
BIO-FUEL
"Feed maize" is being used increasingly for heating; specialized corn stoves (similar to wood stoves) are available and use either feed maize or wood pellets to generate heat. Maize cobs are also used as a biomass fuel source. Maize is relatively cheap and home-heating furnaces have been developed which use maize kernels as a fuel. They feature a large hopper that feeds the uniformly sized maize kernels (or wood pellets or cherry pits) into the fire.[citation needed]
Maize is increasingly used as a feedstock for the production of ethanol fuel. When considering where to construct an ethanol plant, one of the site selection criteria is to ensure there is locally available feedstock. Ethanol is mixed with gasoline to decrease the amount of pollutants emitted when used to fuel motor vehicles. High fuel prices in mid-2007 led to higher demand for ethanol, which in turn led to higher prices paid to farmers for maize. This led to the 2007 harvest being one of the most profitable maize crops in modern history for farmers. Because of the relationship between fuel and maize, prices paid for the crop now tend to track the price of oil.
The price of food is affected to a certain degree by the use of maize for biofuel production. The cost of transportation, production, and marketing are a large portion (80%) of the price of food in the United States. Higher energy costs affect these costs, especially transportation. The increase in food prices the consumer has been seeing is mainly due to the higher energy cost. The effect of biofuel production on other food crop prices is indirect. Use of maize for biofuel production increases the demand, and therefore price of maize. This, in turn, results in farm acreage being diverted from other food crops to maize production. This reduces the supply of the other food crops and increases their prices.
Maize is widely used in Germany as a feedstock for biogas plants. Here the maize is harvested, shredded then placed in silage clamps from which it is fed into the biogas plants. This process makes use of the whole plant rather than simply using the kernels as in the production of fuel ethanol.
A biomass gasification power plant in Strem near Güssing, Burgenland, Austria, began in 2005. Research is being done to make diesel out of the biogas by the Fischer Tropsch method.
Increasingly, ethanol is being used at low concentrations (10% or less) as an additive in gasoline (gasohol) for motor fuels to increase the octane rating, lower pollutants, and reduce petroleum use (what is nowadays also known as "biofuels" and has been generating an intense debate regarding the human beings' necessity of new sources of energy, on the one hand, and the need to maintain, in regions such as Latin America, the food habits and culture which has been the essence of civilizations such as the one originated in Mesoamerica; the entry, January 2008, of maize among the commercial agreements of NAFTA has increased this debate, considering the bad labor conditions of workers in the fields, and mainly the fact that NAFTA "opened the doors to the import of maize from the United States, where the farmers who grow it receive multimillion-dollar subsidies and other government supports. ... According to OXFAM UK, after NAFTA went into effect, the price of maize in Mexico fell 70% between 1994 and 2001. The number of farm jobs dropped as well: from 8.1 million in 1993 to 6.8 million in 2002. Many of those who found themselves without work were small-scale maize growers."). However, introduction in the northern latitudes of the US of tropical maize for biofuels, and not for human or animal consumption, may potentially alleviate this.
COMMODITY
Maize is bought and sold by investors and price speculators as a tradable commodity using corn futures contracts. These "futures" are traded on the Chicago Board of Trade (CBOT) under ticker symbol C. They are delivered every year in March, May, July, September, and December.
ORNAMENTAL AND OTHER USES
Some forms of the plant are occasionally grown for ornamental use in the garden. For this purpose, variegated and colored leaf forms as well as those with colorful ears are used.
Corncobs can be hollowed out and treated to make inexpensive smoking pipes, first manufactured in the United States in 1869.
An unusual use for maize is to create a "corn maze" (or "maize maze") as a tourist attraction. The idea of a maize maze was introduced by the American Maze Company who created a maze in Pennsylvania in 1993. Traditional mazes are most commonly grown using yew hedges, but these take several years to mature. The rapid growth of a field of maize allows a maze to be laid out using GPS at the start of a growing season and for the maize to grow tall enough to obstruct a visitor's line of sight by the start of the summer. In Canada and the US, these are popular in many farming communities.
Maize kernels can be used in place of sand in a sandboxlike enclosure for children's play.
Stigmas from female maize flowers, popularly called corn silk, are sold as herbal supplements.
Maize is used as a fish bait, called "dough balls". It is particularly popular in Europe for coarse fishing.
Additionally, feed corn is sometimes used by hunters to bait animals such as deer or wild hogs.
UNITED STATES USAGE BREAKDOWN
The breakdown of usage of the 12.1-billion-bushel (307-million-tonne) 2008 US maize crop was as follows, according to the World Agricultural Supply and Demand Estimates Report by the USDA.In the US since 2009/2010, maize feedstock use for ethanol production has somewhat exceeded direct use for livestock feed; maize use for fuel ethanol was 5,130 million bushels (130 million tonnes) in the 2013/2014 marketing year.A fraction of the maize feedstock dry matter used for ethanol production is usefully recovered as DDGS (dried distillers grains with solubles). In the 2010/2011 marketing year, about 29.1 million tonnes of DDGS were fed to US livestock and poultry. Because starch utilization in fermentation for ethanol production leaves other grain constituents more concentrated in the residue, the feed value per kg of DDGS, with regard to ruminant-metabolizable energy and protein, exceeds that of the grain. Feed value for monogastric animals, such as swine and poultry, is somewhat lower than for ruminants.
HAZARDS
PELLAGRA
When maize was first introduced into farming systems other than those used by traditional native-American peoples, it was generally welcomed with enthusiasm for its productivity. However, a widespread problem of malnutrition soon arose wherever maize was introduced as a staple food. This was a mystery, since these types of malnutrition were not normally seen among the indigenous Americans, for whom maize was the principal staple food.
It was eventually discovered that the indigenous Americans had learned to soak maize in alkali — water (the process now known as nixtamalization) — made with ashes and lime (calcium oxide) since at least 1200–1500 BC by Mesoamericans. They did this to liberate the corn hulls, but (unbeknownst to natives or colonists) it coincidentally liberates the B-vitamin niacin, the lack of which was the underlying cause of the condition known as pellagra.
Maize was introduced into the diet of non-indigenous Americans without the necessary cultural knowledge acquired over thousands of years in the Americas. In the late 19th century, pellagra reached epidemic proportions in parts of the southern US, as medical researchers debated two theories for its origin: the deficiency theory (which was eventually shown to be true) said that pellagra was due to a deficiency of some nutrient, and the germ theory said that pellagra was caused by a germ transmitted by stable flies. A third theory, promoted by the eugenicist Charles Davenport, held that people only contracted pellagra if they were susceptible to it due to certain "constitutional, inheritable" traits of the affected individual.
Once alkali processing and dietary variety were understood and applied, pellagra disappeared in the developed world. The development of high lysine maize and the promotion of a more balanced diet have also contributed to its demise. Pellagra still exists today in food-poor areas and refugee camps where people survive on donated maize.
ALLERGY
Maize contains lipid transfer protein, an indigestible protein that survives cooking. This protein has been linked to a rare and understudied allergy to maize in humans. The allergic reaction can cause skin rash, swelling or itching of mucous membranes, diarrhea, vomiting, asthma and, in severe cases, anaphylaxis. It is unclear how common this allergy is in the general population.
MYCOTOXINS
Fungicide application does not reduce fungal growth or mycotoxin dramatically, although it can be a part of a successful reduction strategy. Among the most common toxins are those produced by Aspergillus and Fusarium spp. The most common toxins are aflatoxins, fumonisins, zearalenone, and ochratoxin A. Bt maize discourages insect vectors and by so doing it dramatically reduces concentrations of fumonisins, significantly reduces aflatoxins, but only mildly reduces others.
ART
Maize has been an essential crop in the Andes since the pre-Columbian era. The Moche culture from Northern Peru made ceramics from earth, water, and fire. This pottery was a sacred substance, formed in significant shapes and used to represent important themes. Maize was represented anthropomorphically as well as naturally.
In the United States, maize ears along with tobacco leaves are carved into the capitals of columns in the United States Capitol building. Maize itself is sometimes used for temporary architectural detailing when the intent is to celebrate the fall season, local agricultural productivity and culture. Bundles of dried maize stalks are often displayed along with pumpkins, gourds and straw in autumnal displays outside homes and businesses. A well-known example of architectural use is the Corn Palace in Mitchell, South Dakota, which uses cobs and ears of colored maize to implement a mural design that is recycled annually. Another well-known example is the Field of Corn sculpture in Dublin, Ohio, where hundreds of concrete ears of corn stand in a grassy field.
A maize stalk with two ripe ears is depicted on the reverse of the Croatian 1 lipa coin, minted since 1993.
WIKIPEDIA
Go to the Book with image in the Internet Archive
Title: United States Naval Medical Bulletin Vol. 7, Nos. 1-4, 1913
Creator: U.S. Navy. Bureau of Medicine and Surgery
Publisher:
Sponsor:
Contributor:
Date: 1913
Language: eng
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Table of Contents</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface VII</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Rotch method of roentgenographic age determination, by Harold W. Smith,
passed assistant surgeon, United States Navy 1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Physical training in the United States naval service, by J. A. Murphy, surgeon,
United States Navy 20</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The present status of color blindness, by G. B. Trible, passed
assistant surgeon, United States Navy 28</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The organization and finances of the Bureau of Medicine and Surgery, by
W. S. Gibson, chief clerk Bureau Medicine and Surgery 39</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The United States Naval Hospital, Las Animas, Colo., the Navy's sanatorium
for tuberculosis, by Philip Leach, medical director, United States Navy 53</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hospital ships for fishing fleets, by J. L. Neilson, surgeon, United
States Navy 64</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Prevention of the spread of infectious diseases on shipboard, by E. R. Stitt,
medical inspector, United States Navy 70</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The treatment of the insane in the Navy, by G. A. Riker, passed
assistant surgeon, United States Navy 77</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Intestinal parasites and diseases found in Guam, by C. P. Kindleberger,
surgeon, United States Navy 86</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The clinical manifestations of pityriasis rosea, by W. D. Owens, passed
assistant surgeon, United States Navy 93</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">An easy method for the cultivation of the gonococcus, by G. F. Clark, passed
assistant surgeon, United States Navy 99</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some statistical observations concerning tattooing as seen by the
recruiting surgeon, by A. Farenholt, surgeon, United States Navy 100</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report on flat foot, by Bruce Elmore, acting assistant surgeon, United States
Navy 102</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A note in regard to the height and weight, at different ages, of
applicants at the recruiting station, Cleveland, Ohio, by J. E. Gill, passed
assistant surgeon, United States Navy 103</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 105</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the miscellaneous collection 105</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Apparatus for obtaining blood from a vein, or from the heart of an
animal, by G. F. Clark, passed assistant surgeon, United States Navy 107</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Diet list for use on board ship, designed by B. F. Jenness, passed
assistant surgeon, United States Navy 108</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Three cases demonstrating the need for care in diagnosis of lead
poisoning and appendicitis, by J. S. Woodward, passed assistant surgeon, United
States Navy 109</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Loose bodies in the knee joint, with report of two cases, by A. M.
Fauntleroy, surgeon, and L. M. Schmidt, passed assistant surgeon, United States
Navy 110</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Korsakow's psychosis, with report of a case, by Heber Butts, passed
assistant surgeon, United States Navy 113</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Multiple compound fracture of the skull, with hemorrhage from longitudinal
sinus, by E. W. Phillips, assistant surgeon, United States Navy 121</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of sudden death during thoracentesis, by E. O. J. Eytinge,
passed assistant surgeon, United States Navy 124</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Extensive carcinoma of stomach and omentum complicating pulmonary tuberculosis,
by G. D. Hale, passed assistant surgeon, United States Navy 125</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eighteen cases resembling climatic bubo, by R. G. Heiner, passed assistant
surgeon, United States Navy 126</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The present status of first aid in the Navy 127</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Naval Medical School laboratories 128</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Fractures of the long bones 129</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. — -Auricular fibrillation. The rapid cure of amoebic dysentery
and hepatitis by hypodermic injections of soluble salts of emetine. The effects
of college athletics on after life. ByA.W. Dunbar and J. L. Neilson 131</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. —Neprectomy without drainage for tuberculous kidney. Embryonic
bands and membranes about the caecum. The recognition and treatment of lesions
of the right iliac fossae other than appendicitis. By R. Spear and H. C. Curl
136</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. —A device for keeping garbage cans in place. The
sanitary aspect of a besieged town. Sunstroke —a heresy. The Bimple life. By C.
N. Fiske and R. C. Ransdell 139</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. —Notes on a hitherto unknown "summer
fever" of the German East African coast. By R. 0. Ransdell. Climatic bubo.
The value of certain vermifuges in the treatment of ankylostomiasis. Quinine
prophylaxis in malaria. Some observations upon the healing of wounds in
sleeping-sickness <span> </span>patients. By E. R.
Stitt 141</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —Structure of the posterior
extremity in the female ankylostoma and necator. The cultivation of malarial
plasmodia. The periodicity-lacking microfilariae. On</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">the length of life of the rat-flea apart from its host. By E. R. Stitt.
The occurrence and virulence of pneumococci in the circulating blood during
lobar pneumonia and the susceptibility of pneumococcus strains to univalent
antipneumococcus serum. The complement fixation test in the differential
diagnosis of acute and chronic gonococcic arthritis. A diluting fluid for
standardization of vaccines with the hvmocytometer. By M. E. Higgins and G. F.
Clark 145</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. —Studies in bacterial metabolism, by C. N.
Fiske. Improvement in the technique of sampling urine for microscopic examination.
Surgical disinfection of the hands with iodine, followed by decolorization with
sodium bisulphate. Determination of the chemical reaction of urine. Detection
of blood in urine and other physiological fluids. Chemistry of silver therapy.
Sensitive test for the detection of albumin in urine. The influence of dry and
moist air on gaseous metabolism. Has the temperature of the blood any influence
on the gaseous metabolism of man? Estimation of dirt in milk. By E.W. Brown and
O. G. Ruge . 149</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. —Chronic irido-cyclitis. The cerebrospinal fluid
as an aid to diagnosis in suppurative meningitis of otitic origin. Additional
experiments on the excretion of hexamethylenamine in the ocular humers. By G.
B. Trible 155</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous.— Care of surgical and laboratory instruments in the
Tropics, by E. R. Stitt 156</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Administration of typhoid prophylactic at the Naval Hospital, Yokohama,
Japan, by E. M. Shipp, surgeon, United States Navy 159</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of laboratory work performed at Cafiacao Naval Hospital, by C.
S. Butler, surgeon, United States Navy 161</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 2</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface vii</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Mental and moral training for war, by J. P. Leys, surgeon, United
States Navy 165</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A few remarks on the detention and probation system of punishment, and
a classification of the offenses of the personnel of the United States Naval</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Disciplinary Barracks, by W. L. Mann, passed assistant surgeon, United States
Navy 174</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some of the opinions of Baron Larrey, by John Chalmers Da Costa,
assistant surgeon, Medical Reserve Corps, United States Navy 183</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Gangosa, by W. M. Kerr, passed assistant surgeon, United States Navy
188</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some laboratory notes upon the bacillus of dysentery, by C. S. Butler,
surgeon, United States Navy 200</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Traumatic dislocation of the patella, by Morris B. Miller, assistant
surgeon, Medical Reserve Corps, United States Navy 215</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Further observations on the value of studying the pulse rate with the
blood pressure in croupous pneumonia, by H. A. Hare, assistant surgeon, Medical
Reserve Corps, United States Navy..., 218</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Treatment of frambesia with salvarsan, by E. U. Reed, passed assistant surgeon,
United States Navy 220</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Cutaneous anthrax, with report of a case, by E. C. White, passed
assistant surgeon, United States Navy 222</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Essence of orange-ether anaesthesia, by C. M. Oman, surgeon, United
States Navy 231</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Iodine sterilization as now used at the United States Naval Hospital,
Norfolk, Va., by W. M. Garton, surgeon, United States Navy 234</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene of the personnel below decks, by B. F. Jenness, passed
assistant surgeon, United States Navy 236</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to pathological collection 243</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helrainthological collection 243</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A collapsible chair for eye, ear, nose, and throat work on board ship,
by A. H. Robnett, passed assistant surgeon, United States Navy 245</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">An apparatus for intravenous medication, by N. T. McLean, passed
assistant surgeon, United States Navy 246</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chart for the correction of gas volumes, by E. R. Noyes, chief
pharmacist, United States Navy 247</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of cholecystitis presenting some interesting features and some
knotty points in diagnosis, by N. J. Blackwood, surgeon, United States Navy. .
. 249</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case of cholera on the U. S. S. Helena and notes on a
Shanghai epidemic, by W. A. Bloedorn, assistant surgeon, United States Navy 251</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case of membraneous pericolitis, by E. L. Woods, passed
assistant surgeon, United States Navy 252</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case of chronic urticaria showing dermography, by George C.
Thomas, passed assistant surgeon, United States Navy 253</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case of poisoning by sea-urchin, by W. S. Pugh, passed
assistant surgeon, United States Navy 254</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of malaria treated with salvarsan, by E. U. Reed, passed
assistant surgeon, United States Navy 255</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The physical qualification of recruits, by C. F. Stokes, Surgeon
General, United States Navy k 257</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Statistical report of the health of the British Navy, covering the year
1911. .258</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —The relation of anaphylaxis to immunity and disease.
By G. F.Clark. Disorders of the pituitary body. Induced pneumothorax in the
treatment of pulmonary disease. Antityphoid vaccination in children. By A. W.
Dunbar and J. L. Neilson 261</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. —Principles of general naval war surgery. Post-anaesthetic
paralyses. By H. G. Beyer. Extraocular hernia. Spontaneous rupture of the malarial
spleen. By R. Spear and H. C. Curl 269</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. —Gaseous disinfection of equipment in the
field. By J. L. Neilson. New rapid method for the bacteriological examination
of water and application for the testing of springs and filter beds. Decomposition
and its microscopical detection in some food products. By E. W. Brown. A
substitute for fresh air. Some observations on metabolism in connection with an
experimental march. El servicio de desratizacion y la peste bubonica. Report on
water purification by chloride of lime at Bir-id-Dehib camp, Malta. By C. N.
Fiske and R. C. Ransdell 277</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — The etiology of beriberi. Recent research on
cholera in India. The destruction of crescents: conclusions regarding the
prevention of malaria by the administration of quinine. A case of blackwater fever,
showing the cell inclusions of Leishman. The kala-azar problem. By E. R. Stitt
283</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —Insect porters of
bacterial infections. Experimental amoebic dysentery and liver abscess in cats.
Uber das Vorkommen und die Lebensbedingiuigen von Ankylostomen und Strongyloides
Larven in Daressalam. By E. R. Stitt. The demonstration of the treponema
pallidum in the brain in cases of general paralysis. On anaphylatoxina and
endotoxins of the typhoid bacillus. By M. E. Higgins and G. F. Clark 287</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. —The chemical interpretations of the
serological content of the blood and cerebrospinal fluid, with some reference
to cytology and chemistry of the latter, in mental diseases. Mett's method for determining
the activity of pepsin and the acidity maximum of peptic</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">digestion. A new method for determining sugar. The relations of phenol and
M-cresol to proteins. The mechanism of disinfection. Ointment bases. Merck's
Annual Report, Vol. XXV. By E. W. Brown and O. G. Ruge . . 292</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat.— The ozena problem. Paths of encephalic
infection in otitis. General anesthesic in cataract work. Studies of ocular tonometry.
By G. B. Trible 297</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous. —Athletics and candidates for service abroad. Direct
Roentgen pictures without the use of plates. By J. L. Neilson 299</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters: </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Account of an outbreak of malaria on the U. S. S. Tacoma resultant upon
a visit to Tampico, Mexico, by J. B. Kaufman, passed assistant surgeon, United
States Navy 301</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Expedition to Santo Domingo, by S. S. Rodman, surgeon, United States Navy
303</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Sanitary conditions found in, and surgical aid rendered to the wounded
at Puerto Plata and Monte Cristi, Santo Domingo, by R. A. Warner, passed assistant
surgeon, United States Navy 305</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medico-military report on a cruise in Santo Domingan waters, by H. E.
Jenkins, assistant surgeon, United States Navy 308</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A brief note on the Cape Cruz-Caailda surveying expedition from a
medical officer's point of view, by E. E. Woodland, assistant surgeon, United
States Navy 309</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medico-military report on ports of the west coast of Central America
and Mexico, by C. B. Camerer, passed assistant surgeon, United States Navy 311</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Note upon temperature of Filipino applicants for enlistment, by Allan
E. Peck, surgeon, United States Navy 320</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 3</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> Preface vii</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Weak foot, by R. C. Holcomb, surgeon, United States Navy 321</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A new theory of ventilation and its application in certain situations
aboard ship, by F. L. Pleadwell, surgeon, United States Navy 332</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Aural affections dependent upon visceral lesions and functional nervous
disorders, by J. J. Richardson, assistant surgeon, Medical Reserve Corps, United
States Navy 339</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The detection of the feeble-minded applicant for enlistment; value of
the Binet-Simon scale as a diagnostic aid, by A. R. Schier, acting assistant surgeon,
United States Navy 345</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Lost trails, a plea for naval medical biographies, by J. D. Gatewood,
medical director, United States Navy 360</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Absorbable animal ligatures, by T. A. Berryhill, medical director,
United States Navy 367</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A model camp hospital ashore, by E. Thompson, surgeon, United States Navy
375</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Defensive elements of the body, by W. W. Wilkinson, assistant surgeon, Medical
Reserve Corps, United States Navy 381</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Advantages of Paris from a medical postgraduate point of view, by R. A.
Bachmann, surgeon, United States Navy 391</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Estimation of total nitrogen, by E. R. Noyes, chief pharmacist, United States
Navy 394</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection <span> </span>397</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthological collection 397</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The use of a three-way cock in the intravenous administration of
salvarsan, by R. E. Stoops, passed assistant surgeon, United States Navy 399</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A suggested improvement of the present form of the sanitary scuttle
butt, by W. E. Eaton, assistant surgeon, United States Navy 400</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case showing mirror writing and associated movements
without palsy, by G. B. Crow, passed assistant surgeon, United States Navy 403</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Transplantation of bone, by C. M. Oman, surgeon, United States Navy 406</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Prevention of the complications of gonorrheal infection, by F. L.
Benton, surgeon, United Slates Navy 409</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The first aid treatment of burns and scalds by live steam, by A.
Stuart, surgeon, United States Navy 410</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of six-day fever, by M. S. Elliott, surgeon, United States Navy
412</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Punctured wound of knee joint by the spine of a stingray, by N. J.
Black wood, surgeon, United States Navy 413</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of cocaine poisoning with suicidal tendencies, by W. A.
Bloedorn, assistant surgeon, United States Navy 415</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Poisoning by petroleum spirits, by M. S. Elliott, surgeon, United
States Navy 416</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment : </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Mental fitness. Biographical data, by C. F. Stokes, surgeon general, United
States Navy 417</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. — Diseases observed at Derna during the Italo-Turkish
War. Mumps with orchitis and absence of parotiditis. By H. G. Beyer. Treatment
of gonorrhea with heated bougies. By W. E. Eaton. Diagnosis between pneumonia
and appendicitis. By L. W. Johnson. Experiments to determine the rate of
absorbability and intensity of action of quinine given hypodermically and by
the mouth. By C. N. Fiske. The use of antityphoid vaccine during the course of
an epidemic. Measles. Clinical observations of carbonic acid brine baths on the
circulation. High arterial tension; high tension hypertrophy of the heart.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The relation of bronchial asthma to pathological conditions of the
nose. "Osier's sign" and cutaneous phenomena sometimes associated
with heart disease. Nephritic hypertension. By A. W. Dunbar and G. B. Crow 421</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. —Rapid cure of suppurating buboes and of abscesses. Gunshot wounds
of the thorax, observed at Bengasi during the Italo-Turkish War. Gunshot wounds
treated in the military hospital at Palermo. By H. G. Beyer. The sterilization
of skin and wounds. By C. N. Fiske. Bastedo's sign: a new symptom of chronic
appendicitis. Adrenalin in chloroform anesthesia. A simple method of blood
transfusion. By L. W. Johnson. Excision and suture in the treatment of dense,
close urethral strictures. Operative fixation as a cause of delay in union of fractures.
The arrest of hemorrhage from bone by plugging with soft tissues. Membranous
pericolitis and allied conditions of the ileocecal region. Acute perforation of
duodenal and gastric ulcers. Observati6ns on the anatomy of inguinal hernia.
Osteoplasty. By H. C. Curl and R. A. Warner 434</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. — The action on man of vapors of technical and hygienic
importance. XXX, Nitric acid. XXXI, The "nitrous gases." By E. W.
Brown. On the discolored spots sometimes found on chilled beef. Bacteriology of
incinerator smoke and ash. Leprosy and the bedbug. The regulation of body
temperature in extremes of dry heat. Experiences with spraying mosquitoes.
Artificial house cooling in the Tropics. Portable ozone outfit for military
use. By C. N. Fiske and R.C. Ransdell <span> </span>449</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — Cases of beri-beri. By H. G. Beyer. Glossina morsitans
as carriers of sleeping sickness. By R. C. Ransdell. Salvarsan treatment of
ulcerating processes. Chinese spenomegaly. Relapse in malarial infections. The
leprosy bacillus. By E. R. Stitt. . 454</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. — Transmission of
relapsing fever by lice. Trichostrongylus colubriformis, a human parasite. By
E. R. Stitt. Spirochneta pallida in conjunctival secretions. By H. G. Beyer. A
method of staining the capsule of the pueumococcus. By. G. B. Crow. Experiments
in the transmission of scarlet fever to the lower monkeys. Studies in smallpox
and vaccination. Protozoallike structures in the blood in a case of black-water
fever. By A. B. Clifford and G. F. Clark 461</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. — On a new test for indican in the urine. By H.
G. Beyer. Adrenalin in emergency treatment of noncorrosive poisoning. By L. W.
Johnson. Determination of pepsin activity. Test for the detection of albumen in
urine. Behavior of mercury in the human and animal organism?. Estimation of
mercury in the urine and in the tissues. Method of estimating sugar. Quantitative
reduction of methylene blue by milk bacteria. By E. W. Brown <span> </span>465</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. — Blinding by sunlight. Enucleation in the treatment
of panophthalmitis. Ocular headache. On the tolerance of the vitreous to
dislocated lenses, as an index to reclination in given cases. Treatment of
nasal synechiae with mica plates. By G. B. Trible 469</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of work done in the wards of the naval hospital, Norfolk, during
the year 1912, by L. M. Schmidt, passed assistant surgeon, United States Navy
471</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of relief work in Turkey, by D. C. Walton, assistant surgeon,
United States Navy 473</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Notes on sanitary conditions along the Yangtze River, by R. H. Laning, assistant
surgeon, United States Navy 475</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Yangtze Valley, by J. J. O'Malley, assistant surgeon, United States
Navy 478</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 4</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface vii</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some aspects of the prophylaxis of typhoid fever by the injection of
killed cultures, by C. S. Butler, surgeon, United States Navy 489</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">William Longshaw, jr., assistant surgeon, United States Navy, by J. D. Gatewood,
medical director, United States Navy 503</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Intraperitoneal rupture of the bladder, by R. B. Williams, surgeon,
United States Navy 517</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Nitrous oxide-oxygen anesthesia. Rebreathing method of administration
in general surgery, by H. F. Strine, surgeon. United States Navy. . 521</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Leukaemia, with report of a case of the lymphatic type, by H. L.
Kelley, passed assistant surgeon. United States Navy 524</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Hospital Corps, by G. A. Riker, passed assistant surgeon, United
States Navy 533</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Veru montanitis, by H. W. Cole, passed assistant surgeon. United States
Navy 537</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tests for color blindness, by G. B. Trible, passed assistant surgeon,
United States Navy 542</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical work in American Samoa, by E. U. Reed, passed assistant
surgeon, United States Navy 546</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Recurrent dislocation of shoulder, by R. B. Williams, surgeon. United States
Navy 552</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The medical department in warfare, by A. W. Dunbar, surgeon, United States
Navy 555</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 573</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthological collection 573</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Iodized gauze for the first aid packet, by F. E. McCullough, surgeon,
United States Navy 575</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Incinerator, by A. Farenholt, surgeon, United States Navy 576</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Two cases of thermic fever occurring in the fireroom of a battleship,
by J. L. Neilson, surgeon, United States Navy 579</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Traumatic neuritis of brachial plexus, by W. A. Bloedorn, assistant
surgeon, United States Navy 583</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Typhoid fever with perforation, by N. J. Blackwood, surgeon, United States
Navy 584</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Anaphylaxis with death, by W. H. Connor, passed assistant surgeon, United
States Navy 586</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Two cases simulating appendicitis, by F. M. Furlong, surgeon, United States
Navy 588</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment: Page.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical Corps representation at the Naval War College 591</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Training school for native nurses in Samoa 592</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Annual report of the health of the Imperial Japanese Navy for the year
1910. 592</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. — On the origin of dreams. By H. G. Beyer. Occurrence
of the syphilitic organism in the brain in paresis. By G. A. Riker. Solubility
of white lead in human gastric juice and its bearing on the</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">hygiene of the lead industries. By L. W. Johnson. Psychosis following carbon-monoxide
poisoning with complete recovery. Relations of internal secretions to mental
conditions. Administration of ox bile in the</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">treatment of hyperacidity and of gastric and duodenal ulcer. New laboratory
test for cancer and sarcoma, also a method of separating bile acids and
pigment, indican being obtained if present. Pathology of syphilitic aortitis
with a contribution to the formation of aneurism. Tests for hepatic function
and diseases under experimental conditions. By A. W. Dunbar and G. B. Crow -.
595</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. — Hernial formations caused by deficiencies in the peritoneum.
By H. G. Beyer. Chronic intestinal stasis. By R. Spear. Surgical method of
clearing up chronic typhoid carriers. By L. \Y. Johnson. An analysis and study
of 724 major amputations. Arthroplasty. Proctoclysis —an experimental study.
The first successful case of resection of the thoracic portion of the esophagus
for carcinoma. The kinetic theory of shock and its prevention through
anoci-association. By H. C. Curl and R. A. Warner 605</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. — Search for pathogenic microbes in raw river water
and in crude sewage. Observations on the effects of muscular exercise upon man.
By E. W. Brown. On the physiology of the open-air treatment. My experiences
relative to malarial prophylaxis on board a battleship. By C. N. Fiske and R.
C. Ransdell 618</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — Two cases of climatic bubo. By L. W. Johnson. Polyueuritis
gallinarum caused by different foodstuffs. By E. R. Stitt. 625 </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —Treponemata in the brain
in general paresis. Identity of entameba histolytica and entameba tetragena,
with observations upon the morphology" and life cycle of entameba
histolytica. The breeding places of phlebotomus. By E. R. Stitt. An
experimental investigation of the cytological changes produced in epithelial
cells by long-continued irritation. Effect of Rontgen and radium radiations
upon the vitality of the cells of mouse carcinoma. A contribution to the
etiology of pernicious anemia. The complement</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">content of the blood in malignant disease. By A. B. Clifford and G. F.
Clark 626</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. — Some modern problems in nutrition. By H. G. Beyer.
New reagent for detecting blood. Rapid clinical method for the estimation of
urea in urine. Preservation of milk samples for analysis. Dentifrices and their
ingredients. By E. W. Brown and O. G. Ruge. . . 633</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. — Treatment of persistent otorrhea in
infants and young children by the establishment of post-auricular drainage. Parinaud'a
conjunctivitis; a mycotic disease due to a hitherto undescribed filamentous
organism. The significance of anaphylaxis in ear work. The difficulties of
tonsillectomy and how to deal with them. Notes on the vaccine treatment of
infections which involve the cornea. Intracranial division of the auditory
nerve for persistent tinnitus. By G. H. Trible 637</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous. —The sanitary service in the Japanese Navy during the Russo-Japanese
War. Sanitatsbericht viber die Kaiserlieh Deutsche Marine fur den Zeitraum. By
H. G. Beyer. Annual Report of the Bureau of Health for the Philippine Islands,
1912. By L. W. Johnson. . 640</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of cases of lead poisoning, by L. C. Whiteside, passed assistant
surgeon, United States Navy 647</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Two cases of cerebrospinal fever, by P. S. Rossiter, surgeon, United
States Navy 649</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Lead poisoning 651</p>
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Title: United States Naval Medical Bulletin Vol. 8, Nos. 1-4, 1914
Creator: U.S. Navy. Bureau of Medicine and Surgery
Publisher:
Sponsor:
Contributor:
Date: 1914
Language: eng
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Table of Contents</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface v</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The application of psychiatry to certain military problems, by W. A.
White, M. D 1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Schistosomiasis on the Yangtze River, with report of cases, by R. H.
Laning, assistant surgeon, United States Navy 16</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A brief discussion of matters pertaining to health and sanitation,
observed on the summer practice cruise of 1913 for midshipmen of the third
class, by J. L. Neilson, surgeon, United States Navy 36</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Technique of neosalvarsan administration, and a brief outline of the
treatment for syphilis used at the United States Naval Hospital, Norfolk, Va., by
W. Chambers, passed assistant surgeon, United States Navy 45</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some notes on the disposal of wastes, by A. Farenholt, surgeon, United States
Navy 47</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The medical department on expeditionary duty, by R. E. Hoyt, surgeon, United
States Navy 51</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A new brigade medical outfit, by T. W. Richards, surgeon, United States
Navy 62</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Early diagnosis of cerebrospinal meningitis; report of 10 cases, by G.
F. Cottle, passed assistant surgeon, United States Navy 65</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Comments on mistakes made with the Nomenclature, 1913, Abstract of patients
(Form F), and the Statistical report (Form K), by C. E. Alexander, pharmacist,
United States Navy 70</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Classification of the United States Navy Nomenclature, 1913, by C. E. Alexander,
pharmacist, United States Navy 75</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">On the methods employed for the detection and determination of
disturbances in the sense of equilibrium of flyers. Translated by H. G. Beyer,
medical director, United States Navy, retired 87</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 107</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthological collection 107</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A portable air sampling apparatus for use aboard ship, by E. W. Brown, passed
assistant surgeon, United States Navy 109</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A new design for a sanitary pail 111</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of paresis, with apparent remission, following neosalvarsan, by R.
F. Sheehan, passed assistant surgeon, United States Navy 113</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Case reports from Guam, by E. O. J. Eytinge, passed assistant surgeon, United
States Navy 116</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Stab wound of ascending colon; suture; recovery, by H. C. Curl,
surgeon, United States Navy 123</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Perforation of a duodenal ulcer, by H. F. Strine, surgeon, United
States Navy 124</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Two cases of bone surgery, by R. Spear, surgeon, United States Navy 125</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment: </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Brig. Gen. George II. Torney, Surgeon General United States Army 127</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical ethics in the Navy 127</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical officers in civil practice 128</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —Some anatomic and physiologic principles concerning
pyloric ulcer. By H. C. Curl. Low-priced clinical thermometers; a warning. By.
L. W. Johnson. The value of X-ray examinations in the</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">diagnosis of ulcer of the stomach and duodenum. The primary cause of
rheumatoid arthritis. Strychnine in heart failure. On the treatment of
leukaemia with benzol. By A. W. Dunbar and G. B. Crow 131</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. — Surgical aspects of furuncles and carbuncles. Iodine
idiosyncrasy. By L. W. Johnson. Rectus transplantation for deficiency of
internal oblique muscle in certain cases of inguinal hernia. The technic of
nephro- pyelo- and ureterolithotomy. Recurrence of inguinal hernia. By H. C.
Curl and R. A. Warner 138</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. —Ozone: Its bactericidal, physiologic and
deodorizing action. The alleged purification of air by the ozone machine. By E.
W. Brown. The prevention of dental caries. Gun-running operations in the
Persian Gulf in 1909 and 1910. The croton bug (Ectobia germanica) as a factor
in bacterial dissemination. Fumigation of vessels for the destruction of rats.
Improved moist chamber for mosquito breeding. The necessity for international
reforms in the sanitation of crew spaces on</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">merchant vessels. By C. N. Fiske and R. C. Ransdell 143</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. —The transmissibility of the lepra bacillus by the
bite of the bedbug. By L. W. Johnson. A note on a case of loa loa. Cases of
syphilitic pyrexia simulating tropical fevers. Verruga peruviana, oroya fever
and uta. Ankylostomiasis in Nyasaland. Experimental entamoebic dysentery. By E.
R. Stitt ... 148</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —The relation of the spleen
to the blood destruction and regeneration and to hemolytic jaundice: 6, The
blood picture at various periods after splenectomy. The presence of tubercle
bacilli in the feces. By A. B. Clifford and G. F. Clark 157</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. —Detection of bile pigments in urine. Value of the
guaiacum test for bloodstains. New reagent for the detection of traces of
blood. Estimation of urea. Estimation of uric acid in urine. By E. W. Brown and
O. G. Ruge 158</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. —Probable deleterious effect of salvarsan
on the eye. Effect of salvarsan on the eye. Fate of patients with
parenchymatous keratitis due to hereditary lues. Trachoma, prevalence of, in
the United States. The exploratory needle puncture of the maxillary antrum in
100 tuberculous individuals. Auterobic organisms associated with acute
rhinitis. Toxicity of human tonsils. By E. J. Grow and G. B. Trible 160</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous. —Yearbook of the medical association of
Frankfurt-am-Main. By R. C. Ransdell 163</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Notes on the Clinical Congress of Surgeons. By G. F. Cottle, passed
assistant surgeon, United States Navy 167</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 2</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface v</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of the fourteenth annual meeting of the American Roentgen Ray Society,
by J. R. Phelps, passed assistant surgeon, United States Navy. 171</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Typhoid perforation; five operations with three recoveries, by G. G.
Holladay, assistant surgeon, Medic al Reserve Corps, United States Navy 238</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A satisfactory method for easily obtaining material from syphilitic
lesions, by E. R. Stitt, medical inspector, United States Navy 242</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">An epidemic of measles and mumps in Guam, by C. P. Kindleberger, surgeon,
United States Navy 243</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The feeble-minded from a military standpoint, by A. R. Schier, acting assistant
surgeon, United States Navy 247</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Towne-Lambert elimination treatment of drug addictions, by W. M. Kerr,
passed assistant surgeon, United States Navy 258</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical experiences in the Amazonian Tropics, by C. C. Ammerman, assistant
surgeon, Medical Reserve Corps, United States Navy 270</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 281</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthologieal collection 281</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">An easy method for obtaining blood cultures and for preparing blood
agar, by E. R. Stitt, medical inspector, and G. F. Clark, passed assistant surgeon,
United States Navy 283</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Humidity regulating device on a modern battleship, by R. C. Ransdell, passed
assistant surgeon, United States Navy 284</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Lateral sinus thrombosis, report of case, by G. F. Cottle, passed
assistant surgeon. United States Navy 287</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Twenty-two cases of poisoning by the seeds of Jatropha curcai, by J. A.
Randall, passed assistant surgeon, United States Navy 290</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Shellac bolus in the stomach in fatal case of poisoning by weed
alcohol, by H. F. Hull and O. J. Mink, passed assistant surgeons, United States
Navy 291</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of pneumonia complicated by gangrenous endocarditis, by G. B. Crow,
passed assistant surgeon, United States Navy 292</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —On progressive paralysis in the imperial navy during
the years 1901-1911. By H. G. Beyer. An etiological study of Hodgkin's disease.
The etiology and vaccine treatment of Hodgkin's dis</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">ease. Coryncbacterium hodgkini in lymphatic leukemia and Hodgkin's disease.
Autointoxication and subinfection. Studies of syphilis. The treatment of the
pneumonias. Whooping cough: Etiolcgy, diagnosis, and vaccine treatment. A new
and logical treatment for alcoholism. Intraspinous injection of salvarsanized
serum in the treatment of syphilis of the nervous system, including tabes and
paresis. On the infective nature of certain cases of splenomegaly and Banti's
disease. The etiology and vaccine treatment of Hodgkin's disease. Cultural
results in Hodgkin's disease. By A. W. Dunbar and G. B. Crow 295</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery- Interesting cases of gunshot injury treated at Hankow during
the revolution of 1911 and 1912 in China. The fool's paradise stage in
appendicitis. By L. W. Johnson. The present status of bismuth paste treatment
of suppurative sinuses and empyema. The inguinal route operation for femoral
hernia; with supplementary note on Cooper's ligament. By R. Spear and R. A.
Warner 307</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. — A contribution to the chemistry of
ventilation. The use of ozone in ventilation. By E. \V. Brown. Pulmonary
tuberculosis in the royal navy, with special reference to its detection and
prevention. An investigation into the keeping properties of condensed milks at
the temperature of tropical climates. By C. N. Fiske and R. C. Ransdell 313</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. —Seven days fever of the Indian ports. By L. W.
Johnson. Intestinal schistosomiasis in the Sudan. Disease carriers in our army
in India. Origin and present status of the emetin treatment of amebic
dysentery. The culture of leishmania from the finger blood of a case of Indian
kala-azar. By E. R. Stitt 315</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —The isolation of
typhoid bacilli from feces by means of brilliant green in fluid medium. By C.
N. Fiske. An efficient and convenient stain for use in the eeneral examination
of blood films. By 0. B. Crow. A contribution to the epidemiology of
poliomyelitis. A contribution to the pathology of epidemic poliomyelitis. A
note on the etiology of epidemic<span>
</span>oliomyelitis. Transmutations within the streptococcus-pneumococcus
group. The etiology of acute rheumatism, articular and muscular. By A. B.
Clifford and G. F. Clark 320</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy.— Centrifugal method for estimating albumin in
urine. Detection of albumin in urine. New indican reaction A report on the
chemistry, technology, and pharmacology of and the legislation pertaining to
methyl alcohol. By E. W. Brown and O. O. Ruge. . 325</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. —The use of local anesthesia in
exenteration of the orbit. Salvarsan in<span>
</span>ophthalmic practice. The effect of salvarsan on the eye. Total blindness
from the toxic action of wood alcohol, with recovery of vision under negative
galvanism. Furunculosis of the external auditory canal; the use of alcohol as a
valuable aid in treatment. Local treatment of Vincent's angina with salvarsan.
Perforated ear drum may be responsible for sudden death in water. The indications
for operating in acute mastoiditis. Turbinotomy. Why is nasal catarrh so
prevalent in the United States? By E. J. Grow and G. B. Trible 330</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous. — The organization and work of the hospital ship Re d’
Italia. ByG. B. Trible 333</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Correspondence concerning the article "Some aspects of the
prophylaxis of typhoid fever by injection of killed cultures," by Surg. C.
S. Butler, United States Navy, which appeared in the Bulletin, October, 1913
339</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Malaria on the U. S. S. Tacoma from February, 1913, to February, 1914.
by I. S. K. Reeves, passed assistant surgeon, United States Navy 344</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Extracts from annual sanitary reports for 1913 345</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 3</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface vii</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Economy and waste in naval hospitals, by E. M. Shipp, surgeon, and P.
J. Waldner, chief pharmacist, United States Navy 357</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The new method of physical training in the United States Navy, by J. A.
Murphy, surgeon, United States Navy 368</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A study of the etiology of gangosa in Guam, by C. P. Kindleberger,
surgeon, United States Navy 381</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Unreliability of Wassermann tests using unheated serum, by E. R. Stitt,
medical inspector, and G. F. Clark, passed assistant surgeon, United States
Navy 410</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Laboratory note on antigens, by G. F. Clark, pasted assistant surgeon,
United States Navy 411</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Prevention of mouth infection, by Joseph Head, M. D., D. D. S 411</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Medical Department at general quarters and preparations for battle,
by A. Farenholt, surgeon, United States Navy 421</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A bacteriological index for dirt in milk, by J. J. Kinyoun, assistant
surgeon, Medical Reserve Corps, United States Navy 435</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Brief description of proposed plan of a fleet hospital ship, based upon
the type auxiliary hull, by E. M. Blackwell, surgeon, United States Navy.. 442</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The diagnostic value of the cutaneous tuberculin test in recruiting, by
E. M. Brown, passed assistant surgeon, United States Navy, retired 448</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 453</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A sanitary mess table for hospitals, by F. M. Bogan, surgeon, United
States Navy 455</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A suggested improvement of the Navy scuttle butt, by E. M. Blackwell,
surgeon, United States Navy 455</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Malaria cured by neosalvarsan, by F. M. Bogan, surgeon, United States
Navy 457</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of rupture of the bladder with fracture of the pelvis, by H. F.
Strine, surgeon, and M. E. Higgins, passed assistant surgeon, United States
Navy. 458</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical observations on the use of succinimid of mercury, by T. W.
Reed, passed assistant surgeon, United States Navy 459</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Points in the post-mortem ligation of the lingual artery, by O. J.
Mink, passed assistant surgeon, United States Navy 462</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Notes on the wounded at Vera Cruz, by H. F. Strine, surgeon, and M. E.
Higgins, passed assistant surgeon. United States Navy 464</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Case reports from the Naval Hospital, Portsmouth, N. H., by F. M.
Bogan, surgeon, United States Navy 469</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —The mouth in the etiology and symptomatology of
general systemic disturbances. Statistique m£dicale de la marine, 1909. By L.
W. Johnson. Antityphoid inoculation. Vaccines from the standpoint of the
physician. The treatment of sciatica. Chronic gastric ulcer and its relation to
gastric carcinoma. The nonprotein nitrogenous constituents of the blood in
chronic vascular nephritis<span>
</span>(arteriosclero-iis) as influenced by the level of protein metabolism.
The influence of diet on hepatic necrosis and toxicity of chloroform. The
rational treatment of tetanus. The comparative value of cardiac remedies. By A.
W. Dunbar and G. B. Crow </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Psychiatry. —Abderhalden's method. Precis de psychiatric Constitutional
immorality. Nine years' experience with manic-depressive insanity. The pupil
and its reflexes in insanity. By R. F. Sheehan.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. —On the occurrence of traumatic dislocations (luxationen) in
the Imperial German Navy during the last 20 years. By H. G. Beyer. The wounding
effects of the Turkish sharp-pointed bullet. By T. W. Richards. Intestinal
obstruction: formation and absorption of toxin. By G. B. Crow </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. —Relation of oysters to the transmission of
infectious diseases. The proper diet in the Tropics, with some pertinent remarks
on the use of alcohol. By E. W. Brown. Report of committee</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">upon period of isolation and exclusion from school in cases of
communicable disease. Resultats d'une enquete relative a la morbidity venerienne
dans la division navale d'Extreme-Orient et aux moyens susceptibles de la
restreindre. Ship's hygiene in the middle of the seventeenth century- Progress in
ship's hygiene during the nineteenth century. The origin of some of the
streptococci found in milk. On the further perfecting of mosquito spraying. By
C. N. Fiske and R. C. Ransdell</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — Le transport, colloidal de medicaments dans le cholera.
By T. W. Richards. Cholera in the Turkish Army. A supposed case of yellow fever
in Jamaica. By L. W. Johnson. Note on a new geographic locality for balantidiosis.
Brief note on Toxoplasma pyroqenes. Note on certain protozoalike bodies in a
case of protracted fever with splenomegaly. The emetine and other treatment of
amebic dysentery and hepatitis, including liver abscess. A study of epidemic dysentery
in the Fiji Islands. By E. R. Stitt</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. — The best method of staining
Treponema pallidum. By C. N. Fiske. Bacteriological methods of meat analysis.
By R. C. Ransdell. Primary tissue lesions in the heart produced by Spirochete
pallida. Ten tests by which a physician may determine when p patient is cured
of gonorrhea. Diagnostic value of percutaneous tuberculin test (Moro). Some
causes of failure of vaccine therapy. A method of increasing the accuracy and
delicacy of the Wassermann reaction: By A. B. Clifford and G. F. Clark</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. —Quantitative test of pancreatic function. A comparison
of various preservatives of urine. A clinical method for the rapid estimation
of the quantity of dextrose in urine. By E. W. Brown and O. G. Ruge</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. —Intraocular pressure. Strauma as an
important factor in diseases of the eye. Carbonic cauterization "in the
treatment of granular ophthalmia. Ocular and other complications of syphilis treated
by salvarsan. Some notes on hay fever. A radiographic study of the mastoid. Ear
complications during typhoid fever. Su di un caso di piccola sanguisuga
cavallina nel bronco destro e su 7 casi di grosse sanguisughe cavalline in
laringe in trachea e rino-faringe. By E. J. Grow and G. B. Trible</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters: </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">American medico-psychological association, by R. F. Sheehan, passed assistant
surgeon, United States Navy 517</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of 11 cases of asphyxiation from coal gas, by L. C. Whiteside,
passed assistant surgeon, United States Navy 522</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Extracts from annual sanitary reports for 1913 — United States Naval
Academy, Annapolis, Md., by A. M. D. McCormick, medical director, United States
Navy 523</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Arkansas, by W. B. Grove, surgeon, United States Navy 524 </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Marine barracks, Camp Elliott, Canal Zone, Panama, by B. H. Dorsey, passed
assistant surgeon, United States Navy 525</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Cincinnati, by J. B. Mears, passed assistant surgeon. United States
Navy 526</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Florida, by M. S. Elliott, surgeon, United States Navy 527</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Naval training station, Great Lakes, Ill., by J. S. Taylor, surgeon, United
States Navy 527</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Naval station, Guam, by C. P. Kindleberger, surgeon, United States Navy
528</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Naval Hospital, Las Animas, Colo., by G. H. Barber, medical inspector, United
States Navy 532</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Nebraska, by E. H. H. Old, passed assistant surgeon, United States
Navy 533</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. North Dakota, by J. C. Pryor, surgeon, United States Navy. .
534</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Navy yard, Olongapo, P. L, by J. S. Woodward, passed assistant surgeon,
United States Navy 536</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. San Francisco, by T. W. Reed, passed assistant surgeon, United
States Navy 537</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Saratoga, by H. R. Hermesch, assistant surgeon, United States Navy
538</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. Scorpion, by E. P. Huff, passed assistant surgeon, United States
Navy 538</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">U. S. S. West Virginia, by O. J. Mink, passed assistant surgeon, United
States Navy 539</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 4</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface V</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some prevailing ideas regarding the treatment of tuberculosis, by
Passed Asst. Surg. G. B. Crow 541</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Training School for the Hospital Corps of the Navy, by Surg. F. E. McCullough
and Passed Asst. Surg. J. B. Kaufman 555</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Khaki dye for white uniforms, by Passed Asst. Surg. W. E. Eaton 561</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some facts and some fancies regarding the unity of yaws and syphilis,
by Surg. C. S. Butler 561</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Quinine prophylaxis of malaria, by Passed Asst. Surg. L. W. McGuire 571</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The nervous system and naval warfare, translated by Surg. T. W.
Richards. 576</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Measles, by Surg. G. F. Freeman 586</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Smallpox and vaccination, by Passed Asst. Surg. T. W. Raison 589</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Rabies; methods of diagnosis and immunization, by Passed Asst. Surg. F.
X. Koltes 597</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Syphilis aboard ship, by Passed Asst. Surg. G. F. Cottle 605</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Systematic recording and treatment of syphilis, by Surg. A. M.
Fauntleroy and Passed Asst. Surg. E. H. H. Old 620</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Organization and station bills of the U. S. naval hospital ship Solace,
by Surg. W. M. Garton 624</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 647</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthological collection 647</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Succinimid of mercury in pyorrhea alveolaris, by Acting Asst. Dental Surg.
P. G. White 649</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of pityriasis rosea, by Surg. R. E. Ledbetter 651</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Emetin in the treatment of amebic abscess of the liver, by Surg. H. F. Strine
and Passed Asst. Surg. L. Sheldon, jr 653 </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Salvarsan in a case of amebic dysentery, by Passed Asst. Surg. O. J.
Mink. . 653</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Laceration of the subclavian artery and complete severing of brachial plexus,
by Surg. H. C. Curl and Passed Asst. Surg. C. B. Camerer 654</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Malarial infection complicating splenectomy, by Surg. H. F. Strine 655</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of gastric hemorrhage; operative interference impossible, by
Passed Arst. Surg. G. E. Robertson 656</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Operation for strangulated hernia, by Passed Asst. Surg. W. S. Pugh 657</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of bronchiectasis with hypertrophic pulmonary osteoarthropathy,
by Passed Asst. Surg. L. C. Whiteside 658</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Systematic recording and treatment of syphilis 665</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences: <span> </span></p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —A note of three cases of enteric fever inoculated
during the incubation period. By T. W. Richards. The modern treatment of
chancroids. The treatment of burns. By W. E. Eaton. Experiments on the curative
value of the intraspinal administration of tetanus antitoxin. Hexamethylenamin.
<span> </span>Hexamethylenamin as an internal
antiseptic in other fluids of the body than urine. Lumbar puncture as a special
procedure for controlling headache in the course of infectious diseases.
Cardiospasm. Acromion auscultation; a new and delicate test in the early
diagnosis of incipient pulmonary tuberculosis.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Diabetes mellitus and its differentiation from alimentary glycosuria.
The complement fixation test in typhoid fever; its comparison with the
agglutination test and blood culture method. By C. B. Crow.. 671</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Mental and nervous diseases. —A voice sign in chorea. By G. B. Crow.
Wassermann reaction and its application to neurology. Epilepsy: a theory of
causation founded upon the clinical manifestations and the therapeutic and
pathological data. Salvarsanized serum (Swift-Ellis treatment) in syphilitic diseases
of the central nervous system. Mental manifestations in tumors of the brain.
Some of the broader issues of the psycho-analytic n movement. Mental disease
and defect in United States troops. By R. Sheehan 6S1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. — Infiltration anesthesia. War surgery. Tenoplasty; tendon transplantation;
tendon substitution; neuroplasty. Carcinoma of the male breast. Visceral
pleureotomy for chronic empyema. By A. M. Fauntleroy and E. H. H. Old 6S8</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. — Further experiences with the Berkefold filter
in the purifying of lead-contaminated water. By T. W. Richards. Experiments in
the destruction of fly larvae in horse manure. By A. B. Clifford. Investigation
relative to the life cycle, brooding, and tome practical moans of reducing the
multiplication of flies in camp. By W. E. Eaton, Humidity and heat stroke;
further observations on an<span> </span>analysis of
50 cases. By C. N. Fiske 693</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — The treatment of aneylostoma anemia. Latent dysentery
or dysentery carriers. Naphthalone for the destruction of mosquitoes. Emetin in
amebic dysentery. By E. R. Stitt 704</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —Meningitis by
injection of pyogenic microbes in the peripheral nerves. The growth of pathogenic
intestinal bacteria in bread. Present status of the complement fixation test in
the diagnosis of gonorrheal infections. Practical application of the luetin
test. By A. B. Clifford and G. F. Clark 707</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. — Misting of eyeglasses. By E. L. Sleeth.
The treatment of ocular syphilis by salvarsan and neo salvarsan. The moving
picture and the eye. Treatment of various forms of ocular syphilis with
salvarsan. Rapid, painless, and bloodless method for removing the inferior
turbinate. Hemorrhage from the superior petrosal sinus. The frequency of
laryngeal tuberculosis in Massachusetts.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Intrinsic cancer of larynx. Treatment of hematoma of the auricle. By E.
J. Grow and G. B. Trible 709</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Care of wounded at Mazatlan and at Villa Union, by Medical Inspector S.
G. Evans 713</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medico-military reports of the occupation of Vera Cruz 715</p>
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Title: United States Naval Medical Bulletin Vol. 7, Nos. 1-4, 1913
Creator: U.S. Navy. Bureau of Medicine and Surgery
Publisher:
Sponsor:
Contributor:
Date: 1913
Language: eng
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Table of Contents</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface VII</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Rotch method of roentgenographic age determination, by Harold W. Smith,
passed assistant surgeon, United States Navy 1</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Physical training in the United States naval service, by J. A. Murphy, surgeon,
United States Navy 20</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The present status of color blindness, by G. B. Trible, passed
assistant surgeon, United States Navy 28</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The organization and finances of the Bureau of Medicine and Surgery, by
W. S. Gibson, chief clerk Bureau Medicine and Surgery 39</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The United States Naval Hospital, Las Animas, Colo., the Navy's sanatorium
for tuberculosis, by Philip Leach, medical director, United States Navy 53</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hospital ships for fishing fleets, by J. L. Neilson, surgeon, United
States Navy 64</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Prevention of the spread of infectious diseases on shipboard, by E. R. Stitt,
medical inspector, United States Navy 70</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The treatment of the insane in the Navy, by G. A. Riker, passed
assistant surgeon, United States Navy 77</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Intestinal parasites and diseases found in Guam, by C. P. Kindleberger,
surgeon, United States Navy 86</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The clinical manifestations of pityriasis rosea, by W. D. Owens, passed
assistant surgeon, United States Navy 93</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">An easy method for the cultivation of the gonococcus, by G. F. Clark, passed
assistant surgeon, United States Navy 99</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some statistical observations concerning tattooing as seen by the
recruiting surgeon, by A. Farenholt, surgeon, United States Navy 100</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report on flat foot, by Bruce Elmore, acting assistant surgeon, United States
Navy 102</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A note in regard to the height and weight, at different ages, of
applicants at the recruiting station, Cleveland, Ohio, by J. E. Gill, passed
assistant surgeon, United States Navy 103</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 105</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the miscellaneous collection 105</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Apparatus for obtaining blood from a vein, or from the heart of an
animal, by G. F. Clark, passed assistant surgeon, United States Navy 107</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Diet list for use on board ship, designed by B. F. Jenness, passed
assistant surgeon, United States Navy 108</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Three cases demonstrating the need for care in diagnosis of lead
poisoning and appendicitis, by J. S. Woodward, passed assistant surgeon, United
States Navy 109</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Loose bodies in the knee joint, with report of two cases, by A. M.
Fauntleroy, surgeon, and L. M. Schmidt, passed assistant surgeon, United States
Navy 110</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Korsakow's psychosis, with report of a case, by Heber Butts, passed
assistant surgeon, United States Navy 113</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Multiple compound fracture of the skull, with hemorrhage from longitudinal
sinus, by E. W. Phillips, assistant surgeon, United States Navy 121</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of sudden death during thoracentesis, by E. O. J. Eytinge,
passed assistant surgeon, United States Navy 124</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Extensive carcinoma of stomach and omentum complicating pulmonary tuberculosis,
by G. D. Hale, passed assistant surgeon, United States Navy 125</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eighteen cases resembling climatic bubo, by R. G. Heiner, passed assistant
surgeon, United States Navy 126</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The present status of first aid in the Navy 127</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Naval Medical School laboratories 128</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Fractures of the long bones 129</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. — -Auricular fibrillation. The rapid cure of amoebic dysentery
and hepatitis by hypodermic injections of soluble salts of emetine. The effects
of college athletics on after life. ByA.W. Dunbar and J. L. Neilson 131</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. —Neprectomy without drainage for tuberculous kidney. Embryonic
bands and membranes about the caecum. The recognition and treatment of lesions
of the right iliac fossae other than appendicitis. By R. Spear and H. C. Curl
136</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. —A device for keeping garbage cans in place. The
sanitary aspect of a besieged town. Sunstroke —a heresy. The Bimple life. By C.
N. Fiske and R. C. Ransdell 139</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. —Notes on a hitherto unknown "summer
fever" of the German East African coast. By R. 0. Ransdell. Climatic bubo.
The value of certain vermifuges in the treatment of ankylostomiasis. Quinine
prophylaxis in malaria. Some observations upon the healing of wounds in
sleeping-sickness <span> </span>patients. By E. R.
Stitt 141</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —Structure of the posterior
extremity in the female ankylostoma and necator. The cultivation of malarial
plasmodia. The periodicity-lacking microfilariae. On</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">the length of life of the rat-flea apart from its host. By E. R. Stitt.
The occurrence and virulence of pneumococci in the circulating blood during
lobar pneumonia and the susceptibility of pneumococcus strains to univalent
antipneumococcus serum. The complement fixation test in the differential
diagnosis of acute and chronic gonococcic arthritis. A diluting fluid for
standardization of vaccines with the hvmocytometer. By M. E. Higgins and G. F.
Clark 145</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. —Studies in bacterial metabolism, by C. N.
Fiske. Improvement in the technique of sampling urine for microscopic examination.
Surgical disinfection of the hands with iodine, followed by decolorization with
sodium bisulphate. Determination of the chemical reaction of urine. Detection
of blood in urine and other physiological fluids. Chemistry of silver therapy.
Sensitive test for the detection of albumin in urine. The influence of dry and
moist air on gaseous metabolism. Has the temperature of the blood any influence
on the gaseous metabolism of man? Estimation of dirt in milk. By E.W. Brown and
O. G. Ruge . 149</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. —Chronic irido-cyclitis. The cerebrospinal fluid
as an aid to diagnosis in suppurative meningitis of otitic origin. Additional
experiments on the excretion of hexamethylenamine in the ocular humers. By G.
B. Trible 155</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous.— Care of surgical and laboratory instruments in the
Tropics, by E. R. Stitt 156</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Administration of typhoid prophylactic at the Naval Hospital, Yokohama,
Japan, by E. M. Shipp, surgeon, United States Navy 159</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of laboratory work performed at Cafiacao Naval Hospital, by C.
S. Butler, surgeon, United States Navy 161</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 2</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface vii</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Mental and moral training for war, by J. P. Leys, surgeon, United
States Navy 165</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A few remarks on the detention and probation system of punishment, and
a classification of the offenses of the personnel of the United States Naval</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Disciplinary Barracks, by W. L. Mann, passed assistant surgeon, United States
Navy 174</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some of the opinions of Baron Larrey, by John Chalmers Da Costa,
assistant surgeon, Medical Reserve Corps, United States Navy 183</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Gangosa, by W. M. Kerr, passed assistant surgeon, United States Navy
188</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some laboratory notes upon the bacillus of dysentery, by C. S. Butler,
surgeon, United States Navy 200</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Traumatic dislocation of the patella, by Morris B. Miller, assistant
surgeon, Medical Reserve Corps, United States Navy 215</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Further observations on the value of studying the pulse rate with the
blood pressure in croupous pneumonia, by H. A. Hare, assistant surgeon, Medical
Reserve Corps, United States Navy..., 218</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Treatment of frambesia with salvarsan, by E. U. Reed, passed assistant surgeon,
United States Navy 220</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Cutaneous anthrax, with report of a case, by E. C. White, passed
assistant surgeon, United States Navy 222</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Essence of orange-ether anaesthesia, by C. M. Oman, surgeon, United
States Navy 231</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Iodine sterilization as now used at the United States Naval Hospital,
Norfolk, Va., by W. M. Garton, surgeon, United States Navy 234</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene of the personnel below decks, by B. F. Jenness, passed
assistant surgeon, United States Navy 236</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to pathological collection 243</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helrainthological collection 243</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A collapsible chair for eye, ear, nose, and throat work on board ship,
by A. H. Robnett, passed assistant surgeon, United States Navy 245</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">An apparatus for intravenous medication, by N. T. McLean, passed
assistant surgeon, United States Navy 246</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chart for the correction of gas volumes, by E. R. Noyes, chief
pharmacist, United States Navy 247</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of cholecystitis presenting some interesting features and some
knotty points in diagnosis, by N. J. Blackwood, surgeon, United States Navy. .
. 249</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case of cholera on the U. S. S. Helena and notes on a
Shanghai epidemic, by W. A. Bloedorn, assistant surgeon, United States Navy 251</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case of membraneous pericolitis, by E. L. Woods, passed
assistant surgeon, United States Navy 252</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case of chronic urticaria showing dermography, by George C.
Thomas, passed assistant surgeon, United States Navy 253</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case of poisoning by sea-urchin, by W. S. Pugh, passed
assistant surgeon, United States Navy 254</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of malaria treated with salvarsan, by E. U. Reed, passed
assistant surgeon, United States Navy 255</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The physical qualification of recruits, by C. F. Stokes, Surgeon
General, United States Navy k 257</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Statistical report of the health of the British Navy, covering the year
1911. .258</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. —The relation of anaphylaxis to immunity and disease.
By G. F.Clark. Disorders of the pituitary body. Induced pneumothorax in the
treatment of pulmonary disease. Antityphoid vaccination in children. By A. W.
Dunbar and J. L. Neilson 261</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. —Principles of general naval war surgery. Post-anaesthetic
paralyses. By H. G. Beyer. Extraocular hernia. Spontaneous rupture of the malarial
spleen. By R. Spear and H. C. Curl 269</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. —Gaseous disinfection of equipment in the
field. By J. L. Neilson. New rapid method for the bacteriological examination
of water and application for the testing of springs and filter beds. Decomposition
and its microscopical detection in some food products. By E. W. Brown. A
substitute for fresh air. Some observations on metabolism in connection with an
experimental march. El servicio de desratizacion y la peste bubonica. Report on
water purification by chloride of lime at Bir-id-Dehib camp, Malta. By C. N.
Fiske and R. C. Ransdell 277</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — The etiology of beriberi. Recent research on
cholera in India. The destruction of crescents: conclusions regarding the
prevention of malaria by the administration of quinine. A case of blackwater fever,
showing the cell inclusions of Leishman. The kala-azar problem. By E. R. Stitt
283</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —Insect porters of
bacterial infections. Experimental amoebic dysentery and liver abscess in cats.
Uber das Vorkommen und die Lebensbedingiuigen von Ankylostomen und Strongyloides
Larven in Daressalam. By E. R. Stitt. The demonstration of the treponema
pallidum in the brain in cases of general paralysis. On anaphylatoxina and
endotoxins of the typhoid bacillus. By M. E. Higgins and G. F. Clark 287</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. —The chemical interpretations of the
serological content of the blood and cerebrospinal fluid, with some reference
to cytology and chemistry of the latter, in mental diseases. Mett's method for determining
the activity of pepsin and the acidity maximum of peptic</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">digestion. A new method for determining sugar. The relations of phenol and
M-cresol to proteins. The mechanism of disinfection. Ointment bases. Merck's
Annual Report, Vol. XXV. By E. W. Brown and O. G. Ruge . . 292</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat.— The ozena problem. Paths of encephalic
infection in otitis. General anesthesic in cataract work. Studies of ocular tonometry.
By G. B. Trible 297</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous. —Athletics and candidates for service abroad. Direct
Roentgen pictures without the use of plates. By J. L. Neilson 299</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters: </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Account of an outbreak of malaria on the U. S. S. Tacoma resultant upon
a visit to Tampico, Mexico, by J. B. Kaufman, passed assistant surgeon, United
States Navy 301</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Expedition to Santo Domingo, by S. S. Rodman, surgeon, United States Navy
303</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Sanitary conditions found in, and surgical aid rendered to the wounded
at Puerto Plata and Monte Cristi, Santo Domingo, by R. A. Warner, passed assistant
surgeon, United States Navy 305</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medico-military report on a cruise in Santo Domingan waters, by H. E.
Jenkins, assistant surgeon, United States Navy 308</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A brief note on the Cape Cruz-Caailda surveying expedition from a
medical officer's point of view, by E. E. Woodland, assistant surgeon, United
States Navy 309</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medico-military report on ports of the west coast of Central America
and Mexico, by C. B. Camerer, passed assistant surgeon, United States Navy 311</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Note upon temperature of Filipino applicants for enlistment, by Allan
E. Peck, surgeon, United States Navy 320</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 3</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> Preface vii</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Weak foot, by R. C. Holcomb, surgeon, United States Navy 321</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A new theory of ventilation and its application in certain situations
aboard ship, by F. L. Pleadwell, surgeon, United States Navy 332</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Aural affections dependent upon visceral lesions and functional nervous
disorders, by J. J. Richardson, assistant surgeon, Medical Reserve Corps, United
States Navy 339</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The detection of the feeble-minded applicant for enlistment; value of
the Binet-Simon scale as a diagnostic aid, by A. R. Schier, acting assistant surgeon,
United States Navy 345</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Lost trails, a plea for naval medical biographies, by J. D. Gatewood,
medical director, United States Navy 360</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Absorbable animal ligatures, by T. A. Berryhill, medical director,
United States Navy 367</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A model camp hospital ashore, by E. Thompson, surgeon, United States Navy
375</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Defensive elements of the body, by W. W. Wilkinson, assistant surgeon, Medical
Reserve Corps, United States Navy 381</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Advantages of Paris from a medical postgraduate point of view, by R. A.
Bachmann, surgeon, United States Navy 391</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Estimation of total nitrogen, by E. R. Noyes, chief pharmacist, United States
Navy 394</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection <span> </span>397</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthological collection 397</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The use of a three-way cock in the intravenous administration of
salvarsan, by R. E. Stoops, passed assistant surgeon, United States Navy 399</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A suggested improvement of the present form of the sanitary scuttle
butt, by W. E. Eaton, assistant surgeon, United States Navy 400</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of a case showing mirror writing and associated movements
without palsy, by G. B. Crow, passed assistant surgeon, United States Navy 403</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Transplantation of bone, by C. M. Oman, surgeon, United States Navy 406</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Prevention of the complications of gonorrheal infection, by F. L.
Benton, surgeon, United Slates Navy 409</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The first aid treatment of burns and scalds by live steam, by A.
Stuart, surgeon, United States Navy 410</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of six-day fever, by M. S. Elliott, surgeon, United States Navy
412</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Punctured wound of knee joint by the spine of a stingray, by N. J.
Black wood, surgeon, United States Navy 413</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">A case of cocaine poisoning with suicidal tendencies, by W. A.
Bloedorn, assistant surgeon, United States Navy 415</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Poisoning by petroleum spirits, by M. S. Elliott, surgeon, United
States Navy 416</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment : </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Mental fitness. Biographical data, by C. F. Stokes, surgeon general, United
States Navy 417</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. — Diseases observed at Derna during the Italo-Turkish
War. Mumps with orchitis and absence of parotiditis. By H. G. Beyer. Treatment
of gonorrhea with heated bougies. By W. E. Eaton. Diagnosis between pneumonia
and appendicitis. By L. W. Johnson. Experiments to determine the rate of
absorbability and intensity of action of quinine given hypodermically and by
the mouth. By C. N. Fiske. The use of antityphoid vaccine during the course of
an epidemic. Measles. Clinical observations of carbonic acid brine baths on the
circulation. High arterial tension; high tension hypertrophy of the heart.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The relation of bronchial asthma to pathological conditions of the
nose. "Osier's sign" and cutaneous phenomena sometimes associated
with heart disease. Nephritic hypertension. By A. W. Dunbar and G. B. Crow 421</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. —Rapid cure of suppurating buboes and of abscesses. Gunshot wounds
of the thorax, observed at Bengasi during the Italo-Turkish War. Gunshot wounds
treated in the military hospital at Palermo. By H. G. Beyer. The sterilization
of skin and wounds. By C. N. Fiske. Bastedo's sign: a new symptom of chronic
appendicitis. Adrenalin in chloroform anesthesia. A simple method of blood
transfusion. By L. W. Johnson. Excision and suture in the treatment of dense,
close urethral strictures. Operative fixation as a cause of delay in union of fractures.
The arrest of hemorrhage from bone by plugging with soft tissues. Membranous
pericolitis and allied conditions of the ileocecal region. Acute perforation of
duodenal and gastric ulcers. Observati6ns on the anatomy of inguinal hernia.
Osteoplasty. By H. C. Curl and R. A. Warner 434</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. — The action on man of vapors of technical and hygienic
importance. XXX, Nitric acid. XXXI, The "nitrous gases." By E. W.
Brown. On the discolored spots sometimes found on chilled beef. Bacteriology of
incinerator smoke and ash. Leprosy and the bedbug. The regulation of body
temperature in extremes of dry heat. Experiences with spraying mosquitoes.
Artificial house cooling in the Tropics. Portable ozone outfit for military
use. By C. N. Fiske and R.C. Ransdell <span> </span>449</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — Cases of beri-beri. By H. G. Beyer. Glossina morsitans
as carriers of sleeping sickness. By R. C. Ransdell. Salvarsan treatment of
ulcerating processes. Chinese spenomegaly. Relapse in malarial infections. The
leprosy bacillus. By E. R. Stitt. . 454</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. — Transmission of
relapsing fever by lice. Trichostrongylus colubriformis, a human parasite. By
E. R. Stitt. Spirochneta pallida in conjunctival secretions. By H. G. Beyer. A
method of staining the capsule of the pueumococcus. By. G. B. Crow. Experiments
in the transmission of scarlet fever to the lower monkeys. Studies in smallpox
and vaccination. Protozoallike structures in the blood in a case of black-water
fever. By A. B. Clifford and G. F. Clark 461</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. — On a new test for indican in the urine. By H.
G. Beyer. Adrenalin in emergency treatment of noncorrosive poisoning. By L. W.
Johnson. Determination of pepsin activity. Test for the detection of albumen in
urine. Behavior of mercury in the human and animal organism?. Estimation of
mercury in the urine and in the tissues. Method of estimating sugar. Quantitative
reduction of methylene blue by milk bacteria. By E. W. Brown <span> </span>465</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. — Blinding by sunlight. Enucleation in the treatment
of panophthalmitis. Ocular headache. On the tolerance of the vitreous to
dislocated lenses, as an index to reclination in given cases. Treatment of
nasal synechiae with mica plates. By G. B. Trible 469</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of work done in the wards of the naval hospital, Norfolk, during
the year 1912, by L. M. Schmidt, passed assistant surgeon, United States Navy
471</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of relief work in Turkey, by D. C. Walton, assistant surgeon,
United States Navy 473</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Notes on sanitary conditions along the Yangtze River, by R. H. Laning, assistant
surgeon, United States Navy 475</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Yangtze Valley, by J. J. O'Malley, assistant surgeon, United States
Navy 478</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Number 4</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;"> </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Preface vii</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Special articles:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Some aspects of the prophylaxis of typhoid fever by the injection of
killed cultures, by C. S. Butler, surgeon, United States Navy 489</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">William Longshaw, jr., assistant surgeon, United States Navy, by J. D. Gatewood,
medical director, United States Navy 503</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Intraperitoneal rupture of the bladder, by R. B. Williams, surgeon,
United States Navy 517</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Nitrous oxide-oxygen anesthesia. Rebreathing method of administration
in general surgery, by H. F. Strine, surgeon. United States Navy. . 521</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Leukaemia, with report of a case of the lymphatic type, by H. L.
Kelley, passed assistant surgeon. United States Navy 524</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The Hospital Corps, by G. A. Riker, passed assistant surgeon, United
States Navy 533</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Veru montanitis, by H. W. Cole, passed assistant surgeon. United States
Navy 537</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tests for color blindness, by G. B. Trible, passed assistant surgeon,
United States Navy 542</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical work in American Samoa, by E. U. Reed, passed assistant
surgeon, United States Navy 546</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Recurrent dislocation of shoulder, by R. B. Williams, surgeon. United States
Navy 552</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">The medical department in warfare, by A. W. Dunbar, surgeon, United States
Navy 555</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">United States Naval Medical School laboratories:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the pathological collection 573</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Additions to the helminthological collection 573</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Suggested devices:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Iodized gauze for the first aid packet, by F. E. McCullough, surgeon,
United States Navy 575</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Incinerator, by A. Farenholt, surgeon, United States Navy 576</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Clinical notes:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Two cases of thermic fever occurring in the fireroom of a battleship,
by J. L. Neilson, surgeon, United States Navy 579</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Traumatic neuritis of brachial plexus, by W. A. Bloedorn, assistant
surgeon, United States Navy 583</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Typhoid fever with perforation, by N. J. Blackwood, surgeon, United States
Navy 584</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Anaphylaxis with death, by W. H. Connor, passed assistant surgeon, United
States Navy 586</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Two cases simulating appendicitis, by F. M. Furlong, surgeon, United States
Navy 588</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Editorial comment: Page.</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Medical Corps representation at the Naval War College 591</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Training school for native nurses in Samoa 592</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Annual report of the health of the Imperial Japanese Navy for the year
1910. 592</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Progress in medical sciences:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">General medicine. — On the origin of dreams. By H. G. Beyer. Occurrence
of the syphilitic organism in the brain in paresis. By G. A. Riker. Solubility
of white lead in human gastric juice and its bearing on the</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">hygiene of the lead industries. By L. W. Johnson. Psychosis following carbon-monoxide
poisoning with complete recovery. Relations of internal secretions to mental
conditions. Administration of ox bile in the</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">treatment of hyperacidity and of gastric and duodenal ulcer. New laboratory
test for cancer and sarcoma, also a method of separating bile acids and
pigment, indican being obtained if present. Pathology of syphilitic aortitis
with a contribution to the formation of aneurism. Tests for hepatic function
and diseases under experimental conditions. By A. W. Dunbar and G. B. Crow -.
595</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Surgery. — Hernial formations caused by deficiencies in the peritoneum.
By H. G. Beyer. Chronic intestinal stasis. By R. Spear. Surgical method of
clearing up chronic typhoid carriers. By L. \Y. Johnson. An analysis and study
of 724 major amputations. Arthroplasty. Proctoclysis —an experimental study.
The first successful case of resection of the thoracic portion of the esophagus
for carcinoma. The kinetic theory of shock and its prevention through
anoci-association. By H. C. Curl and R. A. Warner 605</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Hygiene and sanitation. — Search for pathogenic microbes in raw river water
and in crude sewage. Observations on the effects of muscular exercise upon man.
By E. W. Brown. On the physiology of the open-air treatment. My experiences
relative to malarial prophylaxis on board a battleship. By C. N. Fiske and R.
C. Ransdell 618</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Tropical medicine. — Two cases of climatic bubo. By L. W. Johnson. Polyueuritis
gallinarum caused by different foodstuffs. By E. R. Stitt. 625 </p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Pathology, bacteriology, and animal parasitology. —Treponemata in the brain
in general paresis. Identity of entameba histolytica and entameba tetragena,
with observations upon the morphology" and life cycle of entameba
histolytica. The breeding places of phlebotomus. By E. R. Stitt. An
experimental investigation of the cytological changes produced in epithelial
cells by long-continued irritation. Effect of Rontgen and radium radiations
upon the vitality of the cells of mouse carcinoma. A contribution to the
etiology of pernicious anemia. The complement</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">content of the blood in malignant disease. By A. B. Clifford and G. F.
Clark 626</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Chemistry and pharmacy. — Some modern problems in nutrition. By H. G. Beyer.
New reagent for detecting blood. Rapid clinical method for the estimation of
urea in urine. Preservation of milk samples for analysis. Dentifrices and their
ingredients. By E. W. Brown and O. G. Ruge. . . 633</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Eye, ear, nose, and throat. — Treatment of persistent otorrhea in
infants and young children by the establishment of post-auricular drainage. Parinaud'a
conjunctivitis; a mycotic disease due to a hitherto undescribed filamentous
organism. The significance of anaphylaxis in ear work. The difficulties of
tonsillectomy and how to deal with them. Notes on the vaccine treatment of
infections which involve the cornea. Intracranial division of the auditory
nerve for persistent tinnitus. By G. H. Trible 637</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Miscellaneous. —The sanitary service in the Japanese Navy during the Russo-Japanese
War. Sanitatsbericht viber die Kaiserlieh Deutsche Marine fur den Zeitraum. By
H. G. Beyer. Annual Report of the Bureau of Health for the Philippine Islands,
1912. By L. W. Johnson. . 640</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Reports and letters:</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Report of cases of lead poisoning, by L. C. Whiteside, passed assistant
surgeon, United States Navy 647</p>
<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Two cases of cerebrospinal fever, by P. S. Rossiter, surgeon, United
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<p class="MsoNormal" style="margin-bottom:.0001pt;line-height:normal;">Lead poisoning 651</p>
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Reflexo de Ipê Amarelo (Tabebuia aurea).
Reflexo de Ipê-amarelo no lago do Parque da Cidade, em Brasília, Brasil.
This tree is at Brasília's City's Park, in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Naturgetreue Abblidungen und Beschreibungen der essbaren, schädlichen und verdächtigen Schwämme /
Prag :In Commission in der J. G. Calve'schen Buchhandlung,1831-1846.
Meticillin/Methicillin resistant Staphylococcus aureus on Oxoid Brilliance/Spectra M.R.S.A. selective chromogenic agar
Image used and blogged here at Wired.com - worth a read if your interested.
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first case was identified in Wuhan, China, in December 2019. The disease has since spread worldwide, leading to an ongoing pandemic.
Symptoms of COVID-19 are variable, but often include fever, cough, fatigue, breathing difficulties, and loss of smell and taste. Symptoms begin one to fourteen days after exposure to the virus. Of those people who develop noticeable symptoms, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% suffer critical symptoms (respiratory failure, shock, or multiorgan dysfunction). Older people are more likely to have severe symptoms. At least a third of the people who are infected with the virus remain asymptomatic and do not develop noticeable symptoms at any point in time, but they still can spread the disease.[ Around 20% of those people will remain asymptomatic throughout infection, and the rest will develop symptoms later on, becoming pre-symptomatic rather than asymptomatic and therefore having a higher risk of transmitting the virus to others. Some people continue to experience a range of effects—known as long COVID—for months after recovery, and damage to organs has been observed. Multi-year studies are underway to further investigate the long-term effects of the disease.
The virus that causes COVID-19 spreads mainly when an infected person is in close contact[a] with another person. Small droplets and aerosols containing the virus can spread from an infected person's nose and mouth as they breathe, cough, sneeze, sing, or speak. Other people are infected if the virus gets into their mouth, nose or eyes. The virus may also spread via contaminated surfaces, although this is not thought to be the main route of transmission. The exact route of transmission is rarely proven conclusively, but infection mainly happens when people are near each other for long enough. People who are infected can transmit the virus to another person up to two days before they themselves show symptoms, as can people who do not experience symptoms. People remain infectious for up to ten days after the onset of symptoms in moderate cases and up to 20 days in severe cases. Several testing methods have been developed to diagnose the disease. The standard diagnostic method is by detection of the virus' nucleic acid by real-time reverse transcription polymerase chain reaction (rRT-PCR), transcription-mediated amplification (TMA), or by reverse transcription loop-mediated isothermal amplification (RT-LAMP) from a nasopharyngeal swab.
Preventive measures include physical or social distancing, quarantining, ventilation of indoor spaces, covering coughs and sneezes, hand washing, and keeping unwashed hands away from the face. The use of face masks or coverings has been recommended in public settings to minimise the risk of transmissions. Several vaccines have been developed and several countries have initiated mass vaccination campaigns.
Although work is underway to develop drugs that inhibit the virus, the primary treatment is currently symptomatic. Management involves the treatment of symptoms, supportive care, isolation, and experimental measures.
SIGNS AND SYSTOMS
Symptoms of COVID-19 are variable, ranging from mild symptoms to severe illness. Common symptoms include headache, loss of smell and taste, nasal congestion and rhinorrhea, cough, muscle pain, sore throat, fever, diarrhea, and breathing difficulties. People with the same infection may have different symptoms, and their symptoms may change over time. Three common clusters of symptoms have been identified: one respiratory symptom cluster with cough, sputum, shortness of breath, and fever; a musculoskeletal symptom cluster with muscle and joint pain, headache, and fatigue; a cluster of digestive symptoms with abdominal pain, vomiting, and diarrhea. In people without prior ear, nose, and throat disorders, loss of taste combined with loss of smell is associated with COVID-19.
Most people (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging) and 5% of patients suffer critical symptoms (respiratory failure, shock, or multiorgan dysfunction). At least a third of the people who are infected with the virus do not develop noticeable symptoms at any point in time. These asymptomatic carriers tend not to get tested and can spread the disease. Other infected people will develop symptoms later, called "pre-symptomatic", or have very mild symptoms and can also spread the virus.
As is common with infections, there is a delay between the moment a person first becomes infected and the appearance of the first symptoms. The median delay for COVID-19 is four to five days. Most symptomatic people experience symptoms within two to seven days after exposure, and almost all will experience at least one symptom within 12 days.
Most people recover from the acute phase of the disease. However, some people continue to experience a range of effects for months after recovery—named long COVID—and damage to organs has been observed. Multi-year studies are underway to further investigate the long-term effects of the disease.
CAUSE
TRANSMISSION
Coronavirus disease 2019 (COVID-19) spreads from person to person mainly through the respiratory route after an infected person coughs, sneezes, sings, talks or breathes. A new infection occurs when virus-containing particles exhaled by an infected person, either respiratory droplets or aerosols, get into the mouth, nose, or eyes of other people who are in close contact with the infected person. During human-to-human transmission, an average 1000 infectious SARS-CoV-2 virions are thought to initiate a new infection.
The closer people interact, and the longer they interact, the more likely they are to transmit COVID-19. Closer distances can involve larger droplets (which fall to the ground) and aerosols, whereas longer distances only involve aerosols. Larger droplets can also turn into aerosols (known as droplet nuclei) through evaporation. The relative importance of the larger droplets and the aerosols is not clear as of November 2020; however, the virus is not known to spread between rooms over long distances such as through air ducts. Airborne transmission is able to particularly occur indoors, in high risk locations such as restaurants, choirs, gyms, nightclubs, offices, and religious venues, often when they are crowded or less ventilated. It also occurs in healthcare settings, often when aerosol-generating medical procedures are performed on COVID-19 patients.
Although it is considered possible there is no direct evidence of the virus being transmitted by skin to skin contact. A person could get COVID-19 indirectly by touching a contaminated surface or object before touching their own mouth, nose, or eyes, though this is not thought to be the main way the virus spreads. The virus is not known to spread through feces, urine, breast milk, food, wastewater, drinking water, or via animal disease vectors (although some animals can contract the virus from humans). It very rarely transmits from mother to baby during pregnancy.
Social distancing and the wearing of cloth face masks, surgical masks, respirators, or other face coverings are controls for droplet transmission. Transmission may be decreased indoors with well maintained heating and ventilation systems to maintain good air circulation and increase the use of outdoor air.
The number of people generally infected by one infected person varies. Coronavirus disease 2019 is more infectious than influenza, but less so than measles. It often spreads in clusters, where infections can be traced back to an index case or geographical location. There is a major role of "super-spreading events", where many people are infected by one person.
A person who is infected can transmit the virus to others up to two days before they themselves show symptoms, and even if symptoms never appear. People remain infectious in moderate cases for 7–12 days, and up to two weeks in severe cases. In October 2020, medical scientists reported evidence of reinfection in one person.
VIROLOGY
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel severe acute respiratory syndrome coronavirus. It was first isolated from three people with pneumonia connected to the cluster of acute respiratory illness cases in Wuhan. All structural features of the novel SARS-CoV-2 virus particle occur in related coronaviruses in nature.
Outside the human body, the virus is destroyed by household soap, which bursts its protective bubble.
SARS-CoV-2 is closely related to the original SARS-CoV. It is thought to have an animal (zoonotic) origin. Genetic analysis has revealed that the coronavirus genetically clusters with the genus Betacoronavirus, in subgenus Sarbecovirus (lineage B) together with two bat-derived strains. It is 96% identical at the whole genome level to other bat coronavirus samples (BatCov RaTG13). The structural proteins of SARS-CoV-2 include membrane glycoprotein (M), envelope protein (E), nucleocapsid protein (N), and the spike protein (S). The M protein of SARS-CoV-2 is about 98% similar to the M protein of bat SARS-CoV, maintains around 98% homology with pangolin SARS-CoV, and has 90% homology with the M protein of SARS-CoV; whereas, the similarity is only around 38% with the M protein of MERS-CoV. The structure of the M protein resembles the sugar transporter SemiSWEET.
The many thousands of SARS-CoV-2 variants are grouped into clades. Several different clade nomenclatures have been proposed. Nextstrain divides the variants into five clades (19A, 19B, 20A, 20B, and 20C), while GISAID divides them into seven (L, O, V, S, G, GH, and GR).
Several notable variants of SARS-CoV-2 emerged in late 2020. Cluster 5 emerged among minks and mink farmers in Denmark. After strict quarantines and a mink euthanasia campaign, it is believed to have been eradicated. The Variant of Concern 202012/01 (VOC 202012/01) is believed to have emerged in the United Kingdom in September. The 501Y.V2 Variant, which has the same N501Y mutation, arose independently in South Africa.
SARS-CoV-2 VARIANTS
Three known variants of SARS-CoV-2 are currently spreading among global populations as of January 2021 including the UK Variant (referred to as B.1.1.7) first found in London and Kent, a variant discovered in South Africa (referred to as 1.351), and a variant discovered in Brazil (referred to as P.1).
Using Whole Genome Sequencing, epidemiology and modelling suggest the new UK variant ‘VUI – 202012/01’ (the first Variant Under Investigation in December 2020) transmits more easily than other strains.
PATHOPHYSIOLOGY
COVID-19 can affect the upper respiratory tract (sinuses, nose, and throat) and the lower respiratory tract (windpipe and lungs). The lungs are the organs most affected by COVID-19 because the virus accesses host cells via the enzyme angiotensin-converting enzyme 2 (ACE2), which is most abundant in type II alveolar cells of the lungs. The virus uses a special surface glycoprotein called a "spike" (peplomer) to connect to ACE2 and enter the host cell. The density of ACE2 in each tissue correlates with the severity of the disease in that tissue and decreasing ACE2 activity might be protective, though another view is that increasing ACE2 using angiotensin II receptor blocker medications could be protective. As the alveolar disease progresses, respiratory failure might develop and death may follow.
Whether SARS-CoV-2 is able to invade the nervous system remains unknown. The virus is not detected in the CNS of the majority of COVID-19 people with neurological issues. However, SARS-CoV-2 has been detected at low levels in the brains of those who have died from COVID-19, but these results need to be confirmed. SARS-CoV-2 could cause respiratory failure through affecting the brain stem as other coronaviruses have been found to invade the CNS. While virus has been detected in cerebrospinal fluid of autopsies, the exact mechanism by which it invades the CNS remains unclear and may first involve invasion of peripheral nerves given the low levels of ACE2 in the brain. The virus may also enter the bloodstream from the lungs and cross the blood-brain barrier to gain access to the CNS, possibly within an infected white blood cell.
The virus also affects gastrointestinal organs as ACE2 is abundantly expressed in the glandular cells of gastric, duodenal and rectal epithelium as well as endothelial cells and enterocytes of the small intestine.
The virus can cause acute myocardial injury and chronic damage to the cardiovascular system. An acute cardiac injury was found in 12% of infected people admitted to the hospital in Wuhan, China, and is more frequent in severe disease. Rates of cardiovascular symptoms are high, owing to the systemic inflammatory response and immune system disorders during disease progression, but acute myocardial injuries may also be related to ACE2 receptors in the heart. ACE2 receptors are highly expressed in the heart and are involved in heart function. A high incidence of thrombosis and venous thromboembolism have been found people transferred to Intensive care unit (ICU) with COVID-19 infections, and may be related to poor prognosis. Blood vessel dysfunction and clot formation (as suggested by high D-dimer levels caused by blood clots) are thought to play a significant role in mortality, incidences of clots leading to pulmonary embolisms, and ischaemic events within the brain have been noted as complications leading to death in people infected with SARS-CoV-2. Infection appears to set off a chain of vasoconstrictive responses within the body, constriction of blood vessels within the pulmonary circulation has also been posited as a mechanism in which oxygenation decreases alongside the presentation of viral pneumonia. Furthermore, microvascular blood vessel damage has been reported in a small number of tissue samples of the brains – without detected SARS-CoV-2 – and the olfactory bulbs from those who have died from COVID-19.
Another common cause of death is complications related to the kidneys. Early reports show that up to 30% of hospitalized patients both in China and in New York have experienced some injury to their kidneys, including some persons with no previous kidney problems.
Autopsies of people who died of COVID-19 have found diffuse alveolar damage, and lymphocyte-containing inflammatory infiltrates within the lung.
IMMUNOPATHOLOGY
Although SARS-CoV-2 has a tropism for ACE2-expressing epithelial cells of the respiratory tract, people with severe COVID-19 have symptoms of systemic hyperinflammation. Clinical laboratory findings of elevated IL-2, IL-7, IL-6, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon-γ inducible protein 10 (IP-10), monocyte chemoattractant protein 1 (MCP-1), macrophage inflammatory protein 1-α (MIP-1α), and tumour necrosis factor-α (TNF-α) indicative of cytokine release syndrome (CRS) suggest an underlying immunopathology.
Additionally, people with COVID-19 and acute respiratory distress syndrome (ARDS) have classical serum biomarkers of CRS, including elevated C-reactive protein (CRP), lactate dehydrogenase (LDH), D-dimer, and ferritin.
Systemic inflammation results in vasodilation, allowing inflammatory lymphocytic and monocytic infiltration of the lung and the heart. In particular, pathogenic GM-CSF-secreting T-cells were shown to correlate with the recruitment of inflammatory IL-6-secreting monocytes and severe lung pathology in people with COVID-19 . Lymphocytic infiltrates have also been reported at autopsy.
VIRAL AND HOST FACTORS
VIRUS PROTEINS
Multiple viral and host factors affect the pathogenesis of the virus. The S-protein, otherwise known as the spike protein, is the viral component that attaches to the host receptor via the ACE2 receptors. It includes two subunits: S1 and S2. S1 determines the virus host range and cellular tropism via the receptor binding domain. S2 mediates the membrane fusion of the virus to its potential cell host via the H1 and HR2, which are heptad repeat regions. Studies have shown that S1 domain induced IgG and IgA antibody levels at a much higher capacity. It is the focus spike proteins expression that are involved in many effective COVID-19 vaccines.
The M protein is the viral protein responsible for the transmembrane transport of nutrients. It is the cause of the bud release and the formation of the viral envelope. The N and E protein are accessory proteins that interfere with the host's immune response.
HOST FACTORS
Human angiotensin converting enzyme 2 (hACE2) is the host factor that SARS-COV2 virus targets causing COVID-19. Theoretically the usage of angiotensin receptor blockers (ARB) and ACE inhibitors upregulating ACE2 expression might increase morbidity with COVID-19, though animal data suggest some potential protective effect of ARB. However no clinical studies have proven susceptibility or outcomes. Until further data is available, guidelines and recommendations for hypertensive patients remain.
The virus' effect on ACE2 cell surfaces leads to leukocytic infiltration, increased blood vessel permeability, alveolar wall permeability, as well as decreased secretion of lung surfactants. These effects cause the majority of the respiratory symptoms. However, the aggravation of local inflammation causes a cytokine storm eventually leading to a systemic inflammatory response syndrome.
HOST CYTOKINE RESPONSE
The severity of the inflammation can be attributed to the severity of what is known as the cytokine storm. Levels of interleukin 1B, interferon-gamma, interferon-inducible protein 10, and monocyte chemoattractant protein 1 were all associated with COVID-19 disease severity. Treatment has been proposed to combat the cytokine storm as it remains to be one of the leading causes of morbidity and mortality in COVID-19 disease.
A cytokine storm is due to an acute hyperinflammatory response that is responsible for clinical illness in an array of diseases but in COVID-19, it is related to worse prognosis and increased fatality. The storm causes the acute respiratory distress syndrome, blood clotting events such as strokes, myocardial infarction, encephalitis, acute kidney injury, and vasculitis. The production of IL-1, IL-2, IL-6, TNF-alpha, and interferon-gamma, all crucial components of normal immune responses, inadvertently become the causes of a cytokine storm. The cells of the central nervous system, the microglia, neurons, and astrocytes, are also be involved in the release of pro-inflammatory cytokines affecting the nervous system, and effects of cytokine storms toward the CNS are not uncommon.
DIAGNOSIS
COVID-19 can provisionally be diagnosed on the basis of symptoms and confirmed using reverse transcription polymerase chain reaction (RT-PCR) or other nucleic acid testing of infected secretions. Along with laboratory testing, chest CT scans may be helpful to diagnose COVID-19 in individuals with a high clinical suspicion of infection. Detection of a past infection is possible with serological tests, which detect antibodies produced by the body in response to the infection.
VIRAL TESTING
The standard methods of testing for presence of SARS-CoV-2 are nucleic acid tests, which detects the presence of viral RNA fragments. As these tests detect RNA but not infectious virus, its "ability to determine duration of infectivity of patients is limited." The test is typically done on respiratory samples obtained by a nasopharyngeal swab; however, a nasal swab or sputum sample may also be used. Results are generally available within hours. The WHO has published several testing protocols for the disease.
A number of laboratories and companies have developed serological tests, which detect antibodies produced by the body in response to infection. Several have been evaluated by Public Health England and approved for use in the UK.
The University of Oxford's CEBM has pointed to mounting evidence that "a good proportion of 'new' mild cases and people re-testing positives after quarantine or discharge from hospital are not infectious, but are simply clearing harmless virus particles which their immune system has efficiently dealt with" and have called for "an international effort to standardize and periodically calibrate testing" On 7 September, the UK government issued "guidance for procedures to be implemented in laboratories to provide assurance of positive SARS-CoV-2 RNA results during periods of low prevalence, when there is a reduction in the predictive value of positive test results."
IMAGING
Chest CT scans may be helpful to diagnose COVID-19 in individuals with a high clinical suspicion of infection but are not recommended for routine screening. Bilateral multilobar ground-glass opacities with a peripheral, asymmetric, and posterior distribution are common in early infection. Subpleural dominance, crazy paving (lobular septal thickening with variable alveolar filling), and consolidation may appear as the disease progresses. Characteristic imaging features on chest radiographs and computed tomography (CT) of people who are symptomatic include asymmetric peripheral ground-glass opacities without pleural effusions.
Many groups have created COVID-19 datasets that include imagery such as the Italian Radiological Society which has compiled an international online database of imaging findings for confirmed cases. Due to overlap with other infections such as adenovirus, imaging without confirmation by rRT-PCR is of limited specificity in identifying COVID-19. A large study in China compared chest CT results to PCR and demonstrated that though imaging is less specific for the infection, it is faster and more sensitive.
Coding
In late 2019, the WHO assigned emergency ICD-10 disease codes U07.1 for deaths from lab-confirmed SARS-CoV-2 infection and U07.2 for deaths from clinically or epidemiologically diagnosed COVID-19 without lab-confirmed SARS-CoV-2 infection.
PATHOLOGY
The main pathological findings at autopsy are:
Macroscopy: pericarditis, lung consolidation and pulmonary oedema
Lung findings:
minor serous exudation, minor fibrin exudation
pulmonary oedema, pneumocyte hyperplasia, large atypical pneumocytes, interstitial inflammation with lymphocytic infiltration and multinucleated giant cell formation
diffuse alveolar damage (DAD) with diffuse alveolar exudates. DAD is the cause of acute respiratory distress syndrome (ARDS) and severe hypoxemia.
organisation of exudates in alveolar cavities and pulmonary interstitial fibrosis
plasmocytosis in BAL
Blood: disseminated intravascular coagulation (DIC); leukoerythroblastic reaction
Liver: microvesicular steatosis
PREVENTION
Preventive measures to reduce the chances of infection include staying at home, wearing a mask in public, avoiding crowded places, keeping distance from others, ventilating indoor spaces, washing hands with soap and water often and for at least 20 seconds, practising good respiratory hygiene, and avoiding touching the eyes, nose, or mouth with unwashed hands.
Those diagnosed with COVID-19 or who believe they may be infected are advised by the CDC to stay home except to get medical care, call ahead before visiting a healthcare provider, wear a face mask before entering the healthcare provider's office and when in any room or vehicle with another person, cover coughs and sneezes with a tissue, regularly wash hands with soap and water and avoid sharing personal household items.
The first COVID-19 vaccine was granted regulatory approval on 2 December by the UK medicines regulator MHRA. It was evaluated for emergency use authorization (EUA) status by the US FDA, and in several other countries. Initially, the US National Institutes of Health guidelines do not recommend any medication for prevention of COVID-19, before or after exposure to the SARS-CoV-2 virus, outside the setting of a clinical trial. Without a vaccine, other prophylactic measures, or effective treatments, a key part of managing COVID-19 is trying to decrease and delay the epidemic peak, known as "flattening the curve". This is done by slowing the infection rate to decrease the risk of health services being overwhelmed, allowing for better treatment of current cases, and delaying additional cases until effective treatments or a vaccine become available.
VACCINE
A COVID‑19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus causing coronavirus disease 2019 (COVID‑19). Prior to the COVID‑19 pandemic, there was an established body of knowledge about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), which enabled accelerated development of various vaccine technologies during early 2020. On 10 January 2020, the SARS-CoV-2 genetic sequence data was shared through GISAID, and by 19 March, the global pharmaceutical industry announced a major commitment to address COVID-19.
In Phase III trials, several COVID‑19 vaccines have demonstrated efficacy as high as 95% in preventing symptomatic COVID‑19 infections. As of March 2021, 12 vaccines were authorized by at least one national regulatory authority for public use: two RNA vaccines (the Pfizer–BioNTech vaccine and the Moderna vaccine), four conventional inactivated vaccines (BBIBP-CorV, CoronaVac, Covaxin, and CoviVac), four viral vector vaccines (Sputnik V, the Oxford–AstraZeneca vaccine, Convidicea, and the Johnson & Johnson vaccine), and two protein subunit vaccines (EpiVacCorona and RBD-Dimer). In total, as of March 2021, 308 vaccine candidates were in various stages of development, with 73 in clinical research, including 24 in Phase I trials, 33 in Phase I–II trials, and 16 in Phase III development.
Many countries have implemented phased distribution plans that prioritize those at highest risk of complications, such as the elderly, and those at high risk of exposure and transmission, such as healthcare workers. As of 17 March 2021, 400.22 million doses of COVID‑19 vaccine have been administered worldwide based on official reports from national health agencies. AstraZeneca-Oxford anticipates producing 3 billion doses in 2021, Pfizer-BioNTech 1.3 billion doses, and Sputnik V, Sinopharm, Sinovac, and Johnson & Johnson 1 billion doses each. Moderna targets producing 600 million doses and Convidicea 500 million doses in 2021. By December 2020, more than 10 billion vaccine doses had been preordered by countries, with about half of the doses purchased by high-income countries comprising 14% of the world's population.
SOCIAL DISTANCING
Social distancing (also known as physical distancing) includes infection control actions intended to slow the spread of the disease by minimising close contact between individuals. Methods include quarantines; travel restrictions; and the closing of schools, workplaces, stadiums, theatres, or shopping centres. Individuals may apply social distancing methods by staying at home, limiting travel, avoiding crowded areas, using no-contact greetings, and physically distancing themselves from others. Many governments are now mandating or recommending social distancing in regions affected by the outbreak.
Outbreaks have occurred in prisons due to crowding and an inability to enforce adequate social distancing. In the United States, the prisoner population is aging and many of them are at high risk for poor outcomes from COVID-19 due to high rates of coexisting heart and lung disease, and poor access to high-quality healthcare.
SELF-ISOLATION
Self-isolation at home has been recommended for those diagnosed with COVID-19 and those who suspect they have been infected. Health agencies have issued detailed instructions for proper self-isolation. Many governments have mandated or recommended self-quarantine for entire populations. The strongest self-quarantine instructions have been issued to those in high-risk groups. Those who may have been exposed to someone with COVID-19 and those who have recently travelled to a country or region with the widespread transmission have been advised to self-quarantine for 14 days from the time of last possible exposure.
Face masks and respiratory hygiene
The WHO and the US CDC recommend individuals wear non-medical face coverings in public settings where there is an increased risk of transmission and where social distancing measures are difficult to maintain. This recommendation is meant to reduce the spread of the disease by asymptomatic and pre-symptomatic individuals and is complementary to established preventive measures such as social distancing. Face coverings limit the volume and travel distance of expiratory droplets dispersed when talking, breathing, and coughing. A face covering without vents or holes will also filter out particles containing the virus from inhaled and exhaled air, reducing the chances of infection. But, if the mask include an exhalation valve, a wearer that is infected (maybe without having noticed that, and asymptomatic) would transmit the virus outwards through it, despite any certification they can have. So the masks with exhalation valve are not for the infected wearers, and are not reliable to stop the pandemic in a large scale. Many countries and local jurisdictions encourage or mandate the use of face masks or cloth face coverings by members of the public to limit the spread of the virus.
Masks are also strongly recommended for those who may have been infected and those taking care of someone who may have the disease. When not wearing a mask, the CDC recommends covering the mouth and nose with a tissue when coughing or sneezing and recommends using the inside of the elbow if no tissue is available. Proper hand hygiene after any cough or sneeze is encouraged. Healthcare professionals interacting directly with people who have COVID-19 are advised to use respirators at least as protective as NIOSH-certified N95 or equivalent, in addition to other personal protective equipment.
HAND-WASHING AND HYGIENE
Thorough hand hygiene after any cough or sneeze is required. The WHO also recommends that individuals wash hands often with soap and water for at least 20 seconds, especially after going to the toilet or when hands are visibly dirty, before eating and after blowing one's nose. The CDC recommends using an alcohol-based hand sanitiser with at least 60% alcohol, but only when soap and water are not readily available. For areas where commercial hand sanitisers are not readily available, the WHO provides two formulations for local production. In these formulations, the antimicrobial activity arises from ethanol or isopropanol. Hydrogen peroxide is used to help eliminate bacterial spores in the alcohol; it is "not an active substance for hand antisepsis". Glycerol is added as a humectant.
SURFACE CLEANING
After being expelled from the body, coronaviruses can survive on surfaces for hours to days. If a person touches the dirty surface, they may deposit the virus at the eyes, nose, or mouth where it can enter the body cause infection. Current evidence indicates that contact with infected surfaces is not the main driver of Covid-19, leading to recommendations for optimised disinfection procedures to avoid issues such as the increase of antimicrobial resistance through the use of inappropriate cleaning products and processes. Deep cleaning and other surface sanitation has been criticized as hygiene theater, giving a false sense of security against something primarily spread through the air.
The amount of time that the virus can survive depends significantly on the type of surface, the temperature, and the humidity. Coronaviruses die very quickly when exposed to the UV light in sunlight. Like other enveloped viruses, SARS-CoV-2 survives longest when the temperature is at room temperature or lower, and when the relative humidity is low (<50%).
On many surfaces, including as glass, some types of plastic, stainless steel, and skin, the virus can remain infective for several days indoors at room temperature, or even about a week under ideal conditions. On some surfaces, including cotton fabric and copper, the virus usually dies after a few hours. As a general rule of thumb, the virus dies faster on porous surfaces than on non-porous surfaces.
However, this rule is not absolute, and of the many surfaces tested, two with the longest survival times are N95 respirator masks and surgical masks, both of which are considered porous surfaces.
Surfaces may be decontaminated with 62–71 percent ethanol, 50–100 percent isopropanol, 0.1 percent sodium hypochlorite, 0.5 percent hydrogen peroxide, and 0.2–7.5 percent povidone-iodine. Other solutions, such as benzalkonium chloride and chlorhexidine gluconate, are less effective. Ultraviolet germicidal irradiation may also be used. The CDC recommends that if a COVID-19 case is suspected or confirmed at a facility such as an office or day care, all areas such as offices, bathrooms, common areas, shared electronic equipment like tablets, touch screens, keyboards, remote controls, and ATM machines used by the ill persons should be disinfected. A datasheet comprising the authorised substances to disinfection in the food industry (including suspension or surface tested, kind of surface, use dilution, disinfectant and inocuylum volumes) can be seen in the supplementary material of.
VENTILATION AND AIR FILTRATION
The WHO recommends ventilation and air filtration in public spaces to help clear out infectious aerosols.
HEALTHY DIET AND LIFESTYLE
The Harvard T.H. Chan School of Public Health recommends a healthy diet, being physically active, managing psychological stress, and getting enough sleep.
While there is no evidence that vitamin D is an effective treatment for COVID-19, there is limited evidence that vitamin D deficiency increases the risk of severe COVID-19 symptoms. This has led to recommendations for individuals with vitamin D deficiency to take vitamin D supplements as a way of mitigating the risk of COVID-19 and other health issues associated with a possible increase in deficiency due to social distancing.
TREATMENT
There is no specific, effective treatment or cure for coronavirus disease 2019 (COVID-19), the disease caused by the SARS-CoV-2 virus. Thus, the cornerstone of management of COVID-19 is supportive care, which includes treatment to relieve symptoms, fluid therapy, oxygen support and prone positioning as needed, and medications or devices to support other affected vital organs.
Most cases of COVID-19 are mild. In these, supportive care includes medication such as paracetamol or NSAIDs to relieve symptoms (fever, body aches, cough), proper intake of fluids, rest, and nasal breathing. Good personal hygiene and a healthy diet are also recommended. The U.S. Centers for Disease Control and Prevention (CDC) recommend that those who suspect they are carrying the virus isolate themselves at home and wear a face mask.
People with more severe cases may need treatment in hospital. In those with low oxygen levels, use of the glucocorticoid dexamethasone is strongly recommended, as it can reduce the risk of death. Noninvasive ventilation and, ultimately, admission to an intensive care unit for mechanical ventilation may be required to support breathing. Extracorporeal membrane oxygenation (ECMO) has been used to address the issue of respiratory failure, but its benefits are still under consideration.
Several experimental treatments are being actively studied in clinical trials. Others were thought to be promising early in the pandemic, such as hydroxychloroquine and lopinavir/ritonavir, but later research found them to be ineffective or even harmful. Despite ongoing research, there is still not enough high-quality evidence to recommend so-called early treatment. Nevertheless, in the United States, two monoclonal antibody-based therapies are available for early use in cases thought to be at high risk of progression to severe disease. The antiviral remdesivir is available in the U.S., Canada, Australia, and several other countries, with varying restrictions; however, it is not recommended for people needing mechanical ventilation, and is discouraged altogether by the World Health Organization (WHO), due to limited evidence of its efficacy.
PROGNOSIS
The severity of COVID-19 varies. The disease may take a mild course with few or no symptoms, resembling other common upper respiratory diseases such as the common cold. In 3–4% of cases (7.4% for those over age 65) symptoms are severe enough to cause hospitalization. Mild cases typically recover within two weeks, while those with severe or critical diseases may take three to six weeks to recover. Among those who have died, the time from symptom onset to death has ranged from two to eight weeks. The Italian Istituto Superiore di Sanità reported that the median time between the onset of symptoms and death was twelve days, with seven being hospitalised. However, people transferred to an ICU had a median time of ten days between hospitalisation and death. Prolonged prothrombin time and elevated C-reactive protein levels on admission to the hospital are associated with severe course of COVID-19 and with a transfer to ICU.
Some early studies suggest 10% to 20% of people with COVID-19 will experience symptoms lasting longer than a month.[191][192] A majority of those who were admitted to hospital with severe disease report long-term problems including fatigue and shortness of breath. On 30 October 2020 WHO chief Tedros Adhanom warned that "to a significant number of people, the COVID virus poses a range of serious long-term effects". He has described the vast spectrum of COVID-19 symptoms that fluctuate over time as "really concerning." They range from fatigue, a cough and shortness of breath, to inflammation and injury of major organs – including the lungs and heart, and also neurological and psychologic effects. Symptoms often overlap and can affect any system in the body. Infected people have reported cyclical bouts of fatigue, headaches, months of complete exhaustion, mood swings, and other symptoms. Tedros has concluded that therefore herd immunity is "morally unconscionable and unfeasible".
In terms of hospital readmissions about 9% of 106,000 individuals had to return for hospital treatment within 2 months of discharge. The average to readmit was 8 days since first hospital visit. There are several risk factors that have been identified as being a cause of multiple admissions to a hospital facility. Among these are advanced age (above 65 years of age) and presence of a chronic condition such as diabetes, COPD, heart failure or chronic kidney disease.
According to scientific reviews smokers are more likely to require intensive care or die compared to non-smokers, air pollution is similarly associated with risk factors, and pre-existing heart and lung diseases and also obesity contributes to an increased health risk of COVID-19.
It is also assumed that those that are immunocompromised are at higher risk of getting severely sick from SARS-CoV-2. One research that looked into the COVID-19 infections in hospitalized kidney transplant recipients found a mortality rate of 11%.
See also: Impact of the COVID-19 pandemic on children
Children make up a small proportion of reported cases, with about 1% of cases being under 10 years and 4% aged 10–19 years. They are likely to have milder symptoms and a lower chance of severe disease than adults. A European multinational study of hospitalized children published in The Lancet on 25 June 2020 found that about 8% of children admitted to a hospital needed intensive care. Four of those 582 children (0.7%) died, but the actual mortality rate could be "substantially lower" since milder cases that did not seek medical help were not included in the study.
Genetics also plays an important role in the ability to fight off the disease. For instance, those that do not produce detectable type I interferons or produce auto-antibodies against these may get much sicker from COVID-19. Genetic screening is able to detect interferon effector genes.
Pregnant women may be at higher risk of severe COVID-19 infection based on data from other similar viruses, like SARS and MERS, but data for COVID-19 is lacking.
COMPLICATIONS
Complications may include pneumonia, acute respiratory distress syndrome (ARDS), multi-organ failure, septic shock, and death. Cardiovascular complications may include heart failure, arrhythmias, heart inflammation, and blood clots. Approximately 20–30% of people who present with COVID-19 have elevated liver enzymes, reflecting liver injury.
Neurologic manifestations include seizure, stroke, encephalitis, and Guillain–Barré syndrome (which includes loss of motor functions). Following the infection, children may develop paediatric multisystem inflammatory syndrome, which has symptoms similar to Kawasaki disease, which can be fatal. In very rare cases, acute encephalopathy can occur, and it can be considered in those who have been diagnosed with COVID-19 and have an altered mental status.
LONGER-TERM EFFECTS
Some early studies suggest that that 10 to 20% of people with COVID-19 will experience symptoms lasting longer than a month. A majority of those who were admitted to hospital with severe disease report long-term problems, including fatigue and shortness of breath. About 5-10% of patients admitted to hospital progress to severe or critical disease, including pneumonia and acute respiratory failure.
By a variety of mechanisms, the lungs are the organs most affected in COVID-19.[228] The majority of CT scans performed show lung abnormalities in people tested after 28 days of illness.
People with advanced age, severe disease, prolonged ICU stays, or who smoke are more likely to have long lasting effects, including pulmonary fibrosis. Overall, approximately one third of those investigated after 4 weeks will have findings of pulmonary fibrosis or reduced lung function as measured by DLCO, even in people who are asymptomatic, but with the suggestion of continuing improvement with the passing of more time.
IMMUNITY
The immune response by humans to CoV-2 virus occurs as a combination of the cell-mediated immunity and antibody production, just as with most other infections. Since SARS-CoV-2 has been in the human population only since December 2019, it remains unknown if the immunity is long-lasting in people who recover from the disease. The presence of neutralizing antibodies in blood strongly correlates with protection from infection, but the level of neutralizing antibody declines with time. Those with asymptomatic or mild disease had undetectable levels of neutralizing antibody two months after infection. In another study, the level of neutralizing antibody fell 4-fold 1 to 4 months after the onset of symptoms. However, the lack of antibody in the blood does not mean antibody will not be rapidly produced upon reexposure to SARS-CoV-2. Memory B cells specific for the spike and nucleocapsid proteins of SARS-CoV-2 last for at least 6 months after appearance of symptoms. Nevertheless, 15 cases of reinfection with SARS-CoV-2 have been reported using stringent CDC criteria requiring identification of a different variant from the second infection. There are likely to be many more people who have been reinfected with the virus. Herd immunity will not eliminate the virus if reinfection is common. Some other coronaviruses circulating in people are capable of reinfection after roughly a year. Nonetheless, on 3 March 2021, scientists reported that a much more contagious Covid-19 variant, Lineage P.1, first detected in Japan, and subsequently found in Brazil, as well as in several places in the United States, may be associated with Covid-19 disease reinfection after recovery from an earlier Covid-19 infection.
MORTALITY
Several measures are commonly used to quantify mortality. These numbers vary by region and over time and are influenced by the volume of testing, healthcare system quality, treatment options, time since the initial outbreak, and population characteristics such as age, sex, and overall health. The mortality rate reflects the number of deaths within a specific demographic group divided by the population of that demographic group. Consequently, the mortality rate reflects the prevalence as well as the severity of the disease within a given population. Mortality rates are highly correlated to age, with relatively low rates for young people and relatively high rates among the elderly.
The case fatality rate (CFR) reflects the number of deaths divided by the number of diagnosed cases within a given time interval. Based on Johns Hopkins University statistics, the global death-to-case ratio is 2.2% (2,685,770/121,585,388) as of 18 March 2021. The number varies by region. The CFR may not reflect the true severity of the disease, because some infected individuals remain asymptomatic or experience only mild symptoms, and hence such infections may not be included in official case reports. Moreover, the CFR may vary markedly over time and across locations due to the availability of live virus tests.
INFECTION FATALITY RATE
A key metric in gauging the severity of COVID-19 is the infection fatality rate (IFR), also referred to as the infection fatality ratio or infection fatality risk. This metric is calculated by dividing the total number of deaths from the disease by the total number of infected individuals; hence, in contrast to the CFR, the IFR incorporates asymptomatic and undiagnosed infections as well as reported cases.
CURRENT ESTIMATES
A December 2020 systematic review and meta-analysis estimated that population IFR during the first wave of the pandemic was about 0.5% to 1% in many locations (including France, Netherlands, New Zealand, and Portugal), 1% to 2% in other locations (Australia, England, Lithuania, and Spain), and exceeded 2% in Italy. That study also found that most of these differences in IFR reflected corresponding differences in the age composition of the population and age-specific infection rates; in particular, the metaregression estimate of IFR is very low for children and younger adults (e.g., 0.002% at age 10 and 0.01% at age 25) but increases progressively to 0.4% at age 55, 1.4% at age 65, 4.6% at age 75, and 15% at age 85. These results were also highlighted in a December 2020 report issued by the WHO.
EARLIER ESTIMATES OF IFR
At an early stage of the pandemic, the World Health Organization reported estimates of IFR between 0.3% and 1%.[ On 2 July, The WHO's chief scientist reported that the average IFR estimate presented at a two-day WHO expert forum was about 0.6%. In August, the WHO found that studies incorporating data from broad serology testing in Europe showed IFR estimates converging at approximately 0.5–1%. Firm lower limits of IFRs have been established in a number of locations such as New York City and Bergamo in Italy since the IFR cannot be less than the population fatality rate. As of 10 July, in New York City, with a population of 8.4 million, 23,377 individuals (18,758 confirmed and 4,619 probable) have died with COVID-19 (0.3% of the population).Antibody testing in New York City suggested an IFR of ~0.9%,[258] and ~1.4%. In Bergamo province, 0.6% of the population has died. In September 2020 the U.S. Center for Disease Control & Prevention reported preliminary estimates of age-specific IFRs for public health planning purposes.
SEX DIFFERENCES
Early reviews of epidemiologic data showed gendered impact of the pandemic and a higher mortality rate in men in China and Italy. The Chinese Center for Disease Control and Prevention reported the death rate was 2.8% for men and 1.7% for women. Later reviews in June 2020 indicated that there is no significant difference in susceptibility or in CFR between genders. One review acknowledges the different mortality rates in Chinese men, suggesting that it may be attributable to lifestyle choices such as smoking and drinking alcohol rather than genetic factors. Sex-based immunological differences, lesser prevalence of smoking in women and men developing co-morbid conditions such as hypertension at a younger age than women could have contributed to the higher mortality in men. In Europe, 57% of the infected people were men and 72% of those died with COVID-19 were men. As of April 2020, the US government is not tracking sex-related data of COVID-19 infections. Research has shown that viral illnesses like Ebola, HIV, influenza and SARS affect men and women differently.
ETHNIC DIFFERENCES
In the US, a greater proportion of deaths due to COVID-19 have occurred among African Americans and other minority groups. Structural factors that prevent them from practicing social distancing include their concentration in crowded substandard housing and in "essential" occupations such as retail grocery workers, public transit employees, health-care workers and custodial staff. Greater prevalence of lacking health insurance and care and of underlying conditions such as diabetes, hypertension and heart disease also increase their risk of death. Similar issues affect Native American and Latino communities. According to a US health policy non-profit, 34% of American Indian and Alaska Native People (AIAN) non-elderly adults are at risk of serious illness compared to 21% of white non-elderly adults. The source attributes it to disproportionately high rates of many health conditions that may put them at higher risk as well as living conditions like lack of access to clean water. Leaders have called for efforts to research and address the disparities. In the U.K., a greater proportion of deaths due to COVID-19 have occurred in those of a Black, Asian, and other ethnic minority background. More severe impacts upon victims including the relative incidence of the necessity of hospitalization requirements, and vulnerability to the disease has been associated via DNA analysis to be expressed in genetic variants at chromosomal region 3, features that are associated with European Neanderthal heritage. That structure imposes greater risks that those affected will develop a more severe form of the disease. The findings are from Professor Svante Pääbo and researchers he leads at the Max Planck Institute for Evolutionary Anthropology and the Karolinska Institutet. This admixture of modern human and Neanderthal genes is estimated to have occurred roughly between 50,000 and 60,000 years ago in Southern Europe.
COMORBIDITIES
Most of those who die of COVID-19 have pre-existing (underlying) conditions, including hypertension, diabetes mellitus, and cardiovascular disease. According to March data from the United States, 89% of those hospitalised had preexisting conditions. The Italian Istituto Superiore di Sanità reported that out of 8.8% of deaths where medical charts were available, 96.1% of people had at least one comorbidity with the average person having 3.4 diseases. According to this report the most common comorbidities are hypertension (66% of deaths), type 2 diabetes (29.8% of deaths), Ischemic Heart Disease (27.6% of deaths), atrial fibrillation (23.1% of deaths) and chronic renal failure (20.2% of deaths).
Most critical respiratory comorbidities according to the CDC, are: moderate or severe asthma, pre-existing COPD, pulmonary fibrosis, cystic fibrosis. Evidence stemming from meta-analysis of several smaller research papers also suggests that smoking can be associated with worse outcomes. When someone with existing respiratory problems is infected with COVID-19, they might be at greater risk for severe symptoms. COVID-19 also poses a greater risk to people who misuse opioids and methamphetamines, insofar as their drug use may have caused lung damage.
In August 2020 the CDC issued a caution that tuberculosis infections could increase the risk of severe illness or death. The WHO recommended that people with respiratory symptoms be screened for both diseases, as testing positive for COVID-19 couldn't rule out co-infections. Some projections have estimated that reduced TB detection due to the pandemic could result in 6.3 million additional TB cases and 1.4 million TB related deaths by 2025.
NAME
During the initial outbreak in Wuhan, China, the virus and disease were commonly referred to as "coronavirus" and "Wuhan coronavirus", with the disease sometimes called "Wuhan pneumonia". In the past, many diseases have been named after geographical locations, such as the Spanish flu, Middle East Respiratory Syndrome, and Zika virus. In January 2020, the WHO recommended 2019-nCov and 2019-nCoV acute respiratory disease as interim names for the virus and disease per 2015 guidance and international guidelines against using geographical locations (e.g. Wuhan, China), animal species, or groups of people in disease and virus names in part to prevent social stigma. The official names COVID-19 and SARS-CoV-2 were issued by the WHO on 11 February 2020. Tedros Adhanom explained: CO for corona, VI for virus, D for disease and 19 for when the outbreak was first identified (31 December 2019). The WHO additionally uses "the COVID-19 virus" and "the virus responsible for COVID-19" in public communications.
HISTORY
The virus is thought to be natural and of an animal origin, through spillover infection. There are several theories about where the first case (the so-called patient zero) originated. Phylogenetics estimates that SARS-CoV-2 arose in October or November 2019. Evidence suggests that it descends from a coronavirus that infects wild bats, and spread to humans through an intermediary wildlife host.
The first known human infections were in Wuhan, Hubei, China. A study of the first 41 cases of confirmed COVID-19, published in January 2020 in The Lancet, reported the earliest date of onset of symptoms as 1 December 2019.Official publications from the WHO reported the earliest onset of symptoms as 8 December 2019. Human-to-human transmission was confirmed by the WHO and Chinese authorities by 20 January 2020. According to official Chinese sources, these were mostly linked to the Huanan Seafood Wholesale Market, which also sold live animals. In May 2020 George Gao, the director of the CDC, said animal samples collected from the seafood market had tested negative for the virus, indicating that the market was the site of an early superspreading event, but that it was not the site of the initial outbreak.[ Traces of the virus have been found in wastewater samples that were collected in Milan and Turin, Italy, on 18 December 2019.
By December 2019, the spread of infection was almost entirely driven by human-to-human transmission. The number of coronavirus cases in Hubei gradually increased, reaching 60 by 20 December, and at least 266 by 31 December. On 24 December, Wuhan Central Hospital sent a bronchoalveolar lavage fluid (BAL) sample from an unresolved clinical case to sequencing company Vision Medicals. On 27 and 28 December, Vision Medicals informed the Wuhan Central Hospital and the Chinese CDC of the results of the test, showing a new coronavirus. A pneumonia cluster of unknown cause was observed on 26 December and treated by the doctor Zhang Jixian in Hubei Provincial Hospital, who informed the Wuhan Jianghan CDC on 27 December. On 30 December, a test report addressed to Wuhan Central Hospital, from company CapitalBio Medlab, stated an erroneous positive result for SARS, causing a group of doctors at Wuhan Central Hospital to alert their colleagues and relevant hospital authorities of the result. The Wuhan Municipal Health Commission issued a notice to various medical institutions on "the treatment of pneumonia of unknown cause" that same evening. Eight of these doctors, including Li Wenliang (punished on 3 January), were later admonished by the police for spreading false rumours and another, Ai Fen, was reprimanded by her superiors for raising the alarm.
The Wuhan Municipal Health Commission made the first public announcement of a pneumonia outbreak of unknown cause on 31 December, confirming 27 cases—enough to trigger an investigation.
During the early stages of the outbreak, the number of cases doubled approximately every seven and a half days. In early and mid-January 2020, the virus spread to other Chinese provinces, helped by the Chinese New Year migration and Wuhan being a transport hub and major rail interchange. On 20 January, China reported nearly 140 new cases in one day, including two people in Beijing and one in Shenzhen. Later official data shows 6,174 people had already developed symptoms by then, and more may have been infected. A report in The Lancet on 24 January indicated human transmission, strongly recommended personal protective equipment for health workers, and said testing for the virus was essential due to its "pandemic potential". On 30 January, the WHO declared the coronavirus a Public Health Emergency of International Concern. By this time, the outbreak spread by a factor of 100 to 200 times.
Italy had its first confirmed cases on 31 January 2020, two tourists from China. As of 13 March 2020 the WHO considered Europe the active centre of the pandemic. Italy overtook China as the country with the most deaths on 19 March 2020. By 26 March the United States had overtaken China and Italy with the highest number of confirmed cases in the world. Research on coronavirus genomes indicates the majority of COVID-19 cases in New York came from European travellers, rather than directly from China or any other Asian country. Retesting of prior samples found a person in France who had the virus on 27 December 2019, and a person in the United States who died from the disease on 6 February 2020.
After 55 days without a locally transmitted case, Beijing reported a new COVID-19 case on 11 June 2020 which was followed by two more cases on 12 June. By 15 June there were 79 cases officially confirmed, most of them were people that went to Xinfadi Wholesale Market.
RT-PCR testing of untreated wastewater samples from Brazil and Italy have suggested detection of SARS-CoV-2 as early as November and December 2019, respectively, but the methods of such sewage studies have not been optimised, many have not been peer reviewed, details are often missing, and there is a risk of false positives due to contamination or if only one gene target is detected. A September 2020 review journal article said, "The possibility that the COVID-19 infection had already spread to Europe at the end of last year is now indicated by abundant, even if partially circumstantial, evidence", including pneumonia case numbers and radiology in France and Italy in November and December.
MISINFORMATION
After the initial outbreak of COVID-19, misinformation and disinformation regarding the origin, scale, prevention, treatment, and other aspects of the disease rapidly spread online.
In September 2020, the U.S. CDC published preliminary estimates of the risk of death by age groups in the United States, but those estimates were widely misreported and misunderstood.
OTHER ANIMALS
Humans appear to be capable of spreading the virus to some other animals, a type of disease transmission referred to as zooanthroponosis.
Some pets, especially cats and ferrets, can catch this virus from infected humans. Symptoms in cats include respiratory (such as a cough) and digestive symptoms. Cats can spread the virus to other cats, and may be able to spread the virus to humans, but cat-to-human transmission of SARS-CoV-2 has not been proven. Compared to cats, dogs are less susceptible to this infection. Behaviors which increase the risk of transmission include kissing, licking, and petting the animal.
The virus does not appear to be able to infect pigs, ducks, or chickens at all.[ Mice, rats, and rabbits, if they can be infected at all, are unlikely to be involved in spreading the virus.
Tigers and lions in zoos have become infected as a result of contact with infected humans. As expected, monkeys and great ape species such as orangutans can also be infected with the COVID-19 virus.
Minks, which are in the same family as ferrets, have been infected. Minks may be asymptomatic, and can also spread the virus to humans. Multiple countries have identified infected animals in mink farms. Denmark, a major producer of mink pelts, ordered the slaughter of all minks over fears of viral mutations. A vaccine for mink and other animals is being researched.
RESEARCH
International research on vaccines and medicines in COVID-19 is underway by government organisations, academic groups, and industry researchers. The CDC has classified it to require a BSL3 grade laboratory. There has been a great deal of COVID-19 research, involving accelerated research processes and publishing shortcuts to meet the global demand.
As of December 2020, hundreds of clinical trials have been undertaken, with research happening on every continent except Antarctica. As of November 2020, more than 200 possible treatments had been studied in humans so far.
Transmission and prevention research
Modelling research has been conducted with several objectives, including predictions of the dynamics of transmission, diagnosis and prognosis of infection, estimation of the impact of interventions, or allocation of resources. Modelling studies are mostly based on epidemiological models, estimating the number of infected people over time under given conditions. Several other types of models have been developed and used during the COVID-19 including computational fluid dynamics models to study the flow physics of COVID-19, retrofits of crowd movement models to study occupant exposure, mobility-data based models to investigate transmission, or the use of macroeconomic models to assess the economic impact of the pandemic. Further, conceptual frameworks from crisis management research have been applied to better understand the effects of COVID-19 on organizations worldwide.
TREATMENT-RELATED RESEARCH
Repurposed antiviral drugs make up most of the research into COVID-19 treatments. Other candidates in trials include vasodilators, corticosteroids, immune therapies, lipoic acid, bevacizumab, and recombinant angiotensin-converting enzyme 2.
In March 2020, the World Health Organization (WHO) initiated the Solidarity trial to assess the treatment effects of some promising drugs: an experimental drug called remdesivir; anti-malarial drugs chloroquine and hydroxychloroquine; two anti-HIV drugs, lopinavir/ritonavir; and interferon-beta. More than 300 active clinical trials were underway as of April 2020.
Research on the antimalarial drugs hydroxychloroquine and chloroquine showed that they were ineffective at best, and that they may reduce the antiviral activity of remdesivir. By May 2020, France, Italy, and Belgium had banned the use of hydroxychloroquine as a COVID-19 treatment.
In June, initial results from the randomised RECOVERY Trial in the United Kingdom showed that dexamethasone reduced mortality by one third for people who are critically ill on ventilators and one fifth for those receiving supplemental oxygen. Because this is a well-tested and widely available treatment, it was welcomed by the WHO, which is in the process of updating treatment guidelines to include dexamethasone and other steroids. Based on those preliminary results, dexamethasone treatment has been recommended by the NIH for patients with COVID-19 who are mechanically ventilated or who require supplemental oxygen but not in patients with COVID-19 who do not require supplemental oxygen.
In September 2020, the WHO released updated guidance on using corticosteroids for COVID-19. The WHO recommends systemic corticosteroids rather than no systemic corticosteroids for the treatment of people with severe and critical COVID-19 (strong recommendation, based on moderate certainty evidence). The WHO suggests not to use corticosteroids in the treatment of people with non-severe COVID-19 (conditional recommendation, based on low certainty evidence). The updated guidance was based on a meta-analysis of clinical trials of critically ill COVID-19 patients.
WIKIPEDIA
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first case was identified in Wuhan, China, in December 2019. The disease has since spread worldwide, leading to an ongoing pandemic.
Symptoms of COVID-19 are variable, but often include fever, cough, fatigue, breathing difficulties, and loss of smell and taste. Symptoms begin one to fourteen days after exposure to the virus. Of those people who develop noticeable symptoms, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging), and 5% suffer critical symptoms (respiratory failure, shock, or multiorgan dysfunction). Older people are more likely to have severe symptoms. At least a third of the people who are infected with the virus remain asymptomatic and do not develop noticeable symptoms at any point in time, but they still can spread the disease.[ Around 20% of those people will remain asymptomatic throughout infection, and the rest will develop symptoms later on, becoming pre-symptomatic rather than asymptomatic and therefore having a higher risk of transmitting the virus to others. Some people continue to experience a range of effects—known as long COVID—for months after recovery, and damage to organs has been observed. Multi-year studies are underway to further investigate the long-term effects of the disease.
The virus that causes COVID-19 spreads mainly when an infected person is in close contact[a] with another person. Small droplets and aerosols containing the virus can spread from an infected person's nose and mouth as they breathe, cough, sneeze, sing, or speak. Other people are infected if the virus gets into their mouth, nose or eyes. The virus may also spread via contaminated surfaces, although this is not thought to be the main route of transmission. The exact route of transmission is rarely proven conclusively, but infection mainly happens when people are near each other for long enough. People who are infected can transmit the virus to another person up to two days before they themselves show symptoms, as can people who do not experience symptoms. People remain infectious for up to ten days after the onset of symptoms in moderate cases and up to 20 days in severe cases. Several testing methods have been developed to diagnose the disease. The standard diagnostic method is by detection of the virus' nucleic acid by real-time reverse transcription polymerase chain reaction (rRT-PCR), transcription-mediated amplification (TMA), or by reverse transcription loop-mediated isothermal amplification (RT-LAMP) from a nasopharyngeal swab.
Preventive measures include physical or social distancing, quarantining, ventilation of indoor spaces, covering coughs and sneezes, hand washing, and keeping unwashed hands away from the face. The use of face masks or coverings has been recommended in public settings to minimise the risk of transmissions. Several vaccines have been developed and several countries have initiated mass vaccination campaigns.
Although work is underway to develop drugs that inhibit the virus, the primary treatment is currently symptomatic. Management involves the treatment of symptoms, supportive care, isolation, and experimental measures.
SIGNS AND SYSTOMS
Symptoms of COVID-19 are variable, ranging from mild symptoms to severe illness. Common symptoms include headache, loss of smell and taste, nasal congestion and rhinorrhea, cough, muscle pain, sore throat, fever, diarrhea, and breathing difficulties. People with the same infection may have different symptoms, and their symptoms may change over time. Three common clusters of symptoms have been identified: one respiratory symptom cluster with cough, sputum, shortness of breath, and fever; a musculoskeletal symptom cluster with muscle and joint pain, headache, and fatigue; a cluster of digestive symptoms with abdominal pain, vomiting, and diarrhea. In people without prior ear, nose, and throat disorders, loss of taste combined with loss of smell is associated with COVID-19.
Most people (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, hypoxia, or more than 50% lung involvement on imaging) and 5% of patients suffer critical symptoms (respiratory failure, shock, or multiorgan dysfunction). At least a third of the people who are infected with the virus do not develop noticeable symptoms at any point in time. These asymptomatic carriers tend not to get tested and can spread the disease. Other infected people will develop symptoms later, called "pre-symptomatic", or have very mild symptoms and can also spread the virus.
As is common with infections, there is a delay between the moment a person first becomes infected and the appearance of the first symptoms. The median delay for COVID-19 is four to five days. Most symptomatic people experience symptoms within two to seven days after exposure, and almost all will experience at least one symptom within 12 days.
Most people recover from the acute phase of the disease. However, some people continue to experience a range of effects for months after recovery—named long COVID—and damage to organs has been observed. Multi-year studies are underway to further investigate the long-term effects of the disease.
CAUSE
TRANSMISSION
Coronavirus disease 2019 (COVID-19) spreads from person to person mainly through the respiratory route after an infected person coughs, sneezes, sings, talks or breathes. A new infection occurs when virus-containing particles exhaled by an infected person, either respiratory droplets or aerosols, get into the mouth, nose, or eyes of other people who are in close contact with the infected person. During human-to-human transmission, an average 1000 infectious SARS-CoV-2 virions are thought to initiate a new infection.
The closer people interact, and the longer they interact, the more likely they are to transmit COVID-19. Closer distances can involve larger droplets (which fall to the ground) and aerosols, whereas longer distances only involve aerosols. Larger droplets can also turn into aerosols (known as droplet nuclei) through evaporation. The relative importance of the larger droplets and the aerosols is not clear as of November 2020; however, the virus is not known to spread between rooms over long distances such as through air ducts. Airborne transmission is able to particularly occur indoors, in high risk locations such as restaurants, choirs, gyms, nightclubs, offices, and religious venues, often when they are crowded or less ventilated. It also occurs in healthcare settings, often when aerosol-generating medical procedures are performed on COVID-19 patients.
Although it is considered possible there is no direct evidence of the virus being transmitted by skin to skin contact. A person could get COVID-19 indirectly by touching a contaminated surface or object before touching their own mouth, nose, or eyes, though this is not thought to be the main way the virus spreads. The virus is not known to spread through feces, urine, breast milk, food, wastewater, drinking water, or via animal disease vectors (although some animals can contract the virus from humans). It very rarely transmits from mother to baby during pregnancy.
Social distancing and the wearing of cloth face masks, surgical masks, respirators, or other face coverings are controls for droplet transmission. Transmission may be decreased indoors with well maintained heating and ventilation systems to maintain good air circulation and increase the use of outdoor air.
The number of people generally infected by one infected person varies. Coronavirus disease 2019 is more infectious than influenza, but less so than measles. It often spreads in clusters, where infections can be traced back to an index case or geographical location. There is a major role of "super-spreading events", where many people are infected by one person.
A person who is infected can transmit the virus to others up to two days before they themselves show symptoms, and even if symptoms never appear. People remain infectious in moderate cases for 7–12 days, and up to two weeks in severe cases. In October 2020, medical scientists reported evidence of reinfection in one person.
VIROLOGY
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel severe acute respiratory syndrome coronavirus. It was first isolated from three people with pneumonia connected to the cluster of acute respiratory illness cases in Wuhan. All structural features of the novel SARS-CoV-2 virus particle occur in related coronaviruses in nature.
Outside the human body, the virus is destroyed by household soap, which bursts its protective bubble.
SARS-CoV-2 is closely related to the original SARS-CoV. It is thought to have an animal (zoonotic) origin. Genetic analysis has revealed that the coronavirus genetically clusters with the genus Betacoronavirus, in subgenus Sarbecovirus (lineage B) together with two bat-derived strains. It is 96% identical at the whole genome level to other bat coronavirus samples (BatCov RaTG13). The structural proteins of SARS-CoV-2 include membrane glycoprotein (M), envelope protein (E), nucleocapsid protein (N), and the spike protein (S). The M protein of SARS-CoV-2 is about 98% similar to the M protein of bat SARS-CoV, maintains around 98% homology with pangolin SARS-CoV, and has 90% homology with the M protein of SARS-CoV; whereas, the similarity is only around 38% with the M protein of MERS-CoV. The structure of the M protein resembles the sugar transporter SemiSWEET.
The many thousands of SARS-CoV-2 variants are grouped into clades. Several different clade nomenclatures have been proposed. Nextstrain divides the variants into five clades (19A, 19B, 20A, 20B, and 20C), while GISAID divides them into seven (L, O, V, S, G, GH, and GR).
Several notable variants of SARS-CoV-2 emerged in late 2020. Cluster 5 emerged among minks and mink farmers in Denmark. After strict quarantines and a mink euthanasia campaign, it is believed to have been eradicated. The Variant of Concern 202012/01 (VOC 202012/01) is believed to have emerged in the United Kingdom in September. The 501Y.V2 Variant, which has the same N501Y mutation, arose independently in South Africa.
SARS-CoV-2 VARIANTS
Three known variants of SARS-CoV-2 are currently spreading among global populations as of January 2021 including the UK Variant (referred to as B.1.1.7) first found in London and Kent, a variant discovered in South Africa (referred to as 1.351), and a variant discovered in Brazil (referred to as P.1).
Using Whole Genome Sequencing, epidemiology and modelling suggest the new UK variant ‘VUI – 202012/01’ (the first Variant Under Investigation in December 2020) transmits more easily than other strains.
PATHOPHYSIOLOGY
COVID-19 can affect the upper respiratory tract (sinuses, nose, and throat) and the lower respiratory tract (windpipe and lungs). The lungs are the organs most affected by COVID-19 because the virus accesses host cells via the enzyme angiotensin-converting enzyme 2 (ACE2), which is most abundant in type II alveolar cells of the lungs. The virus uses a special surface glycoprotein called a "spike" (peplomer) to connect to ACE2 and enter the host cell. The density of ACE2 in each tissue correlates with the severity of the disease in that tissue and decreasing ACE2 activity might be protective, though another view is that increasing ACE2 using angiotensin II receptor blocker medications could be protective. As the alveolar disease progresses, respiratory failure might develop and death may follow.
Whether SARS-CoV-2 is able to invade the nervous system remains unknown. The virus is not detected in the CNS of the majority of COVID-19 people with neurological issues. However, SARS-CoV-2 has been detected at low levels in the brains of those who have died from COVID-19, but these results need to be confirmed. SARS-CoV-2 could cause respiratory failure through affecting the brain stem as other coronaviruses have been found to invade the CNS. While virus has been detected in cerebrospinal fluid of autopsies, the exact mechanism by which it invades the CNS remains unclear and may first involve invasion of peripheral nerves given the low levels of ACE2 in the brain. The virus may also enter the bloodstream from the lungs and cross the blood-brain barrier to gain access to the CNS, possibly within an infected white blood cell.
The virus also affects gastrointestinal organs as ACE2 is abundantly expressed in the glandular cells of gastric, duodenal and rectal epithelium as well as endothelial cells and enterocytes of the small intestine.
The virus can cause acute myocardial injury and chronic damage to the cardiovascular system. An acute cardiac injury was found in 12% of infected people admitted to the hospital in Wuhan, China, and is more frequent in severe disease. Rates of cardiovascular symptoms are high, owing to the systemic inflammatory response and immune system disorders during disease progression, but acute myocardial injuries may also be related to ACE2 receptors in the heart. ACE2 receptors are highly expressed in the heart and are involved in heart function. A high incidence of thrombosis and venous thromboembolism have been found people transferred to Intensive care unit (ICU) with COVID-19 infections, and may be related to poor prognosis. Blood vessel dysfunction and clot formation (as suggested by high D-dimer levels caused by blood clots) are thought to play a significant role in mortality, incidences of clots leading to pulmonary embolisms, and ischaemic events within the brain have been noted as complications leading to death in people infected with SARS-CoV-2. Infection appears to set off a chain of vasoconstrictive responses within the body, constriction of blood vessels within the pulmonary circulation has also been posited as a mechanism in which oxygenation decreases alongside the presentation of viral pneumonia. Furthermore, microvascular blood vessel damage has been reported in a small number of tissue samples of the brains – without detected SARS-CoV-2 – and the olfactory bulbs from those who have died from COVID-19.
Another common cause of death is complications related to the kidneys. Early reports show that up to 30% of hospitalized patients both in China and in New York have experienced some injury to their kidneys, including some persons with no previous kidney problems.
Autopsies of people who died of COVID-19 have found diffuse alveolar damage, and lymphocyte-containing inflammatory infiltrates within the lung.
IMMUNOPATHOLOGY
Although SARS-CoV-2 has a tropism for ACE2-expressing epithelial cells of the respiratory tract, people with severe COVID-19 have symptoms of systemic hyperinflammation. Clinical laboratory findings of elevated IL-2, IL-7, IL-6, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon-γ inducible protein 10 (IP-10), monocyte chemoattractant protein 1 (MCP-1), macrophage inflammatory protein 1-α (MIP-1α), and tumour necrosis factor-α (TNF-α) indicative of cytokine release syndrome (CRS) suggest an underlying immunopathology.
Additionally, people with COVID-19 and acute respiratory distress syndrome (ARDS) have classical serum biomarkers of CRS, including elevated C-reactive protein (CRP), lactate dehydrogenase (LDH), D-dimer, and ferritin.
Systemic inflammation results in vasodilation, allowing inflammatory lymphocytic and monocytic infiltration of the lung and the heart. In particular, pathogenic GM-CSF-secreting T-cells were shown to correlate with the recruitment of inflammatory IL-6-secreting monocytes and severe lung pathology in people with COVID-19 . Lymphocytic infiltrates have also been reported at autopsy.
VIRAL AND HOST FACTORS
VIRUS PROTEINS
Multiple viral and host factors affect the pathogenesis of the virus. The S-protein, otherwise known as the spike protein, is the viral component that attaches to the host receptor via the ACE2 receptors. It includes two subunits: S1 and S2. S1 determines the virus host range and cellular tropism via the receptor binding domain. S2 mediates the membrane fusion of the virus to its potential cell host via the H1 and HR2, which are heptad repeat regions. Studies have shown that S1 domain induced IgG and IgA antibody levels at a much higher capacity. It is the focus spike proteins expression that are involved in many effective COVID-19 vaccines.
The M protein is the viral protein responsible for the transmembrane transport of nutrients. It is the cause of the bud release and the formation of the viral envelope. The N and E protein are accessory proteins that interfere with the host's immune response.
HOST FACTORS
Human angiotensin converting enzyme 2 (hACE2) is the host factor that SARS-COV2 virus targets causing COVID-19. Theoretically the usage of angiotensin receptor blockers (ARB) and ACE inhibitors upregulating ACE2 expression might increase morbidity with COVID-19, though animal data suggest some potential protective effect of ARB. However no clinical studies have proven susceptibility or outcomes. Until further data is available, guidelines and recommendations for hypertensive patients remain.
The virus' effect on ACE2 cell surfaces leads to leukocytic infiltration, increased blood vessel permeability, alveolar wall permeability, as well as decreased secretion of lung surfactants. These effects cause the majority of the respiratory symptoms. However, the aggravation of local inflammation causes a cytokine storm eventually leading to a systemic inflammatory response syndrome.
HOST CYTOKINE RESPONSE
The severity of the inflammation can be attributed to the severity of what is known as the cytokine storm. Levels of interleukin 1B, interferon-gamma, interferon-inducible protein 10, and monocyte chemoattractant protein 1 were all associated with COVID-19 disease severity. Treatment has been proposed to combat the cytokine storm as it remains to be one of the leading causes of morbidity and mortality in COVID-19 disease.
A cytokine storm is due to an acute hyperinflammatory response that is responsible for clinical illness in an array of diseases but in COVID-19, it is related to worse prognosis and increased fatality. The storm causes the acute respiratory distress syndrome, blood clotting events such as strokes, myocardial infarction, encephalitis, acute kidney injury, and vasculitis. The production of IL-1, IL-2, IL-6, TNF-alpha, and interferon-gamma, all crucial components of normal immune responses, inadvertently become the causes of a cytokine storm. The cells of the central nervous system, the microglia, neurons, and astrocytes, are also be involved in the release of pro-inflammatory cytokines affecting the nervous system, and effects of cytokine storms toward the CNS are not uncommon.
DIAGNOSIS
COVID-19 can provisionally be diagnosed on the basis of symptoms and confirmed using reverse transcription polymerase chain reaction (RT-PCR) or other nucleic acid testing of infected secretions. Along with laboratory testing, chest CT scans may be helpful to diagnose COVID-19 in individuals with a high clinical suspicion of infection. Detection of a past infection is possible with serological tests, which detect antibodies produced by the body in response to the infection.
VIRAL TESTING
The standard methods of testing for presence of SARS-CoV-2 are nucleic acid tests, which detects the presence of viral RNA fragments. As these tests detect RNA but not infectious virus, its "ability to determine duration of infectivity of patients is limited." The test is typically done on respiratory samples obtained by a nasopharyngeal swab; however, a nasal swab or sputum sample may also be used. Results are generally available within hours. The WHO has published several testing protocols for the disease.
A number of laboratories and companies have developed serological tests, which detect antibodies produced by the body in response to infection. Several have been evaluated by Public Health England and approved for use in the UK.
The University of Oxford's CEBM has pointed to mounting evidence that "a good proportion of 'new' mild cases and people re-testing positives after quarantine or discharge from hospital are not infectious, but are simply clearing harmless virus particles which their immune system has efficiently dealt with" and have called for "an international effort to standardize and periodically calibrate testing" On 7 September, the UK government issued "guidance for procedures to be implemented in laboratories to provide assurance of positive SARS-CoV-2 RNA results during periods of low prevalence, when there is a reduction in the predictive value of positive test results."
IMAGING
Chest CT scans may be helpful to diagnose COVID-19 in individuals with a high clinical suspicion of infection but are not recommended for routine screening. Bilateral multilobar ground-glass opacities with a peripheral, asymmetric, and posterior distribution are common in early infection. Subpleural dominance, crazy paving (lobular septal thickening with variable alveolar filling), and consolidation may appear as the disease progresses. Characteristic imaging features on chest radiographs and computed tomography (CT) of people who are symptomatic include asymmetric peripheral ground-glass opacities without pleural effusions.
Many groups have created COVID-19 datasets that include imagery such as the Italian Radiological Society which has compiled an international online database of imaging findings for confirmed cases. Due to overlap with other infections such as adenovirus, imaging without confirmation by rRT-PCR is of limited specificity in identifying COVID-19. A large study in China compared chest CT results to PCR and demonstrated that though imaging is less specific for the infection, it is faster and more sensitive.
Coding
In late 2019, the WHO assigned emergency ICD-10 disease codes U07.1 for deaths from lab-confirmed SARS-CoV-2 infection and U07.2 for deaths from clinically or epidemiologically diagnosed COVID-19 without lab-confirmed SARS-CoV-2 infection.
PATHOLOGY
The main pathological findings at autopsy are:
Macroscopy: pericarditis, lung consolidation and pulmonary oedema
Lung findings:
minor serous exudation, minor fibrin exudation
pulmonary oedema, pneumocyte hyperplasia, large atypical pneumocytes, interstitial inflammation with lymphocytic infiltration and multinucleated giant cell formation
diffuse alveolar damage (DAD) with diffuse alveolar exudates. DAD is the cause of acute respiratory distress syndrome (ARDS) and severe hypoxemia.
organisation of exudates in alveolar cavities and pulmonary interstitial fibrosis
plasmocytosis in BAL
Blood: disseminated intravascular coagulation (DIC); leukoerythroblastic reaction
Liver: microvesicular steatosis
PREVENTION
Preventive measures to reduce the chances of infection include staying at home, wearing a mask in public, avoiding crowded places, keeping distance from others, ventilating indoor spaces, washing hands with soap and water often and for at least 20 seconds, practising good respiratory hygiene, and avoiding touching the eyes, nose, or mouth with unwashed hands.
Those diagnosed with COVID-19 or who believe they may be infected are advised by the CDC to stay home except to get medical care, call ahead before visiting a healthcare provider, wear a face mask before entering the healthcare provider's office and when in any room or vehicle with another person, cover coughs and sneezes with a tissue, regularly wash hands with soap and water and avoid sharing personal household items.
The first COVID-19 vaccine was granted regulatory approval on 2 December by the UK medicines regulator MHRA. It was evaluated for emergency use authorization (EUA) status by the US FDA, and in several other countries. Initially, the US National Institutes of Health guidelines do not recommend any medication for prevention of COVID-19, before or after exposure to the SARS-CoV-2 virus, outside the setting of a clinical trial. Without a vaccine, other prophylactic measures, or effective treatments, a key part of managing COVID-19 is trying to decrease and delay the epidemic peak, known as "flattening the curve". This is done by slowing the infection rate to decrease the risk of health services being overwhelmed, allowing for better treatment of current cases, and delaying additional cases until effective treatments or a vaccine become available.
VACCINE
A COVID‑19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus causing coronavirus disease 2019 (COVID‑19). Prior to the COVID‑19 pandemic, there was an established body of knowledge about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), which enabled accelerated development of various vaccine technologies during early 2020. On 10 January 2020, the SARS-CoV-2 genetic sequence data was shared through GISAID, and by 19 March, the global pharmaceutical industry announced a major commitment to address COVID-19.
In Phase III trials, several COVID‑19 vaccines have demonstrated efficacy as high as 95% in preventing symptomatic COVID‑19 infections. As of March 2021, 12 vaccines were authorized by at least one national regulatory authority for public use: two RNA vaccines (the Pfizer–BioNTech vaccine and the Moderna vaccine), four conventional inactivated vaccines (BBIBP-CorV, CoronaVac, Covaxin, and CoviVac), four viral vector vaccines (Sputnik V, the Oxford–AstraZeneca vaccine, Convidicea, and the Johnson & Johnson vaccine), and two protein subunit vaccines (EpiVacCorona and RBD-Dimer). In total, as of March 2021, 308 vaccine candidates were in various stages of development, with 73 in clinical research, including 24 in Phase I trials, 33 in Phase I–II trials, and 16 in Phase III development.
Many countries have implemented phased distribution plans that prioritize those at highest risk of complications, such as the elderly, and those at high risk of exposure and transmission, such as healthcare workers. As of 17 March 2021, 400.22 million doses of COVID‑19 vaccine have been administered worldwide based on official reports from national health agencies. AstraZeneca-Oxford anticipates producing 3 billion doses in 2021, Pfizer-BioNTech 1.3 billion doses, and Sputnik V, Sinopharm, Sinovac, and Johnson & Johnson 1 billion doses each. Moderna targets producing 600 million doses and Convidicea 500 million doses in 2021. By December 2020, more than 10 billion vaccine doses had been preordered by countries, with about half of the doses purchased by high-income countries comprising 14% of the world's population.
SOCIAL DISTANCING
Social distancing (also known as physical distancing) includes infection control actions intended to slow the spread of the disease by minimising close contact between individuals. Methods include quarantines; travel restrictions; and the closing of schools, workplaces, stadiums, theatres, or shopping centres. Individuals may apply social distancing methods by staying at home, limiting travel, avoiding crowded areas, using no-contact greetings, and physically distancing themselves from others. Many governments are now mandating or recommending social distancing in regions affected by the outbreak.
Outbreaks have occurred in prisons due to crowding and an inability to enforce adequate social distancing. In the United States, the prisoner population is aging and many of them are at high risk for poor outcomes from COVID-19 due to high rates of coexisting heart and lung disease, and poor access to high-quality healthcare.
SELF-ISOLATION
Self-isolation at home has been recommended for those diagnosed with COVID-19 and those who suspect they have been infected. Health agencies have issued detailed instructions for proper self-isolation. Many governments have mandated or recommended self-quarantine for entire populations. The strongest self-quarantine instructions have been issued to those in high-risk groups. Those who may have been exposed to someone with COVID-19 and those who have recently travelled to a country or region with the widespread transmission have been advised to self-quarantine for 14 days from the time of last possible exposure.
Face masks and respiratory hygiene
The WHO and the US CDC recommend individuals wear non-medical face coverings in public settings where there is an increased risk of transmission and where social distancing measures are difficult to maintain. This recommendation is meant to reduce the spread of the disease by asymptomatic and pre-symptomatic individuals and is complementary to established preventive measures such as social distancing. Face coverings limit the volume and travel distance of expiratory droplets dispersed when talking, breathing, and coughing. A face covering without vents or holes will also filter out particles containing the virus from inhaled and exhaled air, reducing the chances of infection. But, if the mask include an exhalation valve, a wearer that is infected (maybe without having noticed that, and asymptomatic) would transmit the virus outwards through it, despite any certification they can have. So the masks with exhalation valve are not for the infected wearers, and are not reliable to stop the pandemic in a large scale. Many countries and local jurisdictions encourage or mandate the use of face masks or cloth face coverings by members of the public to limit the spread of the virus.
Masks are also strongly recommended for those who may have been infected and those taking care of someone who may have the disease. When not wearing a mask, the CDC recommends covering the mouth and nose with a tissue when coughing or sneezing and recommends using the inside of the elbow if no tissue is available. Proper hand hygiene after any cough or sneeze is encouraged. Healthcare professionals interacting directly with people who have COVID-19 are advised to use respirators at least as protective as NIOSH-certified N95 or equivalent, in addition to other personal protective equipment.
HAND-WASHING AND HYGIENE
Thorough hand hygiene after any cough or sneeze is required. The WHO also recommends that individuals wash hands often with soap and water for at least 20 seconds, especially after going to the toilet or when hands are visibly dirty, before eating and after blowing one's nose. The CDC recommends using an alcohol-based hand sanitiser with at least 60% alcohol, but only when soap and water are not readily available. For areas where commercial hand sanitisers are not readily available, the WHO provides two formulations for local production. In these formulations, the antimicrobial activity arises from ethanol or isopropanol. Hydrogen peroxide is used to help eliminate bacterial spores in the alcohol; it is "not an active substance for hand antisepsis". Glycerol is added as a humectant.
SURFACE CLEANING
After being expelled from the body, coronaviruses can survive on surfaces for hours to days. If a person touches the dirty surface, they may deposit the virus at the eyes, nose, or mouth where it can enter the body cause infection. Current evidence indicates that contact with infected surfaces is not the main driver of Covid-19, leading to recommendations for optimised disinfection procedures to avoid issues such as the increase of antimicrobial resistance through the use of inappropriate cleaning products and processes. Deep cleaning and other surface sanitation has been criticized as hygiene theater, giving a false sense of security against something primarily spread through the air.
The amount of time that the virus can survive depends significantly on the type of surface, the temperature, and the humidity. Coronaviruses die very quickly when exposed to the UV light in sunlight. Like other enveloped viruses, SARS-CoV-2 survives longest when the temperature is at room temperature or lower, and when the relative humidity is low (<50%).
On many surfaces, including as glass, some types of plastic, stainless steel, and skin, the virus can remain infective for several days indoors at room temperature, or even about a week under ideal conditions. On some surfaces, including cotton fabric and copper, the virus usually dies after a few hours. As a general rule of thumb, the virus dies faster on porous surfaces than on non-porous surfaces.
However, this rule is not absolute, and of the many surfaces tested, two with the longest survival times are N95 respirator masks and surgical masks, both of which are considered porous surfaces.
Surfaces may be decontaminated with 62–71 percent ethanol, 50–100 percent isopropanol, 0.1 percent sodium hypochlorite, 0.5 percent hydrogen peroxide, and 0.2–7.5 percent povidone-iodine. Other solutions, such as benzalkonium chloride and chlorhexidine gluconate, are less effective. Ultraviolet germicidal irradiation may also be used. The CDC recommends that if a COVID-19 case is suspected or confirmed at a facility such as an office or day care, all areas such as offices, bathrooms, common areas, shared electronic equipment like tablets, touch screens, keyboards, remote controls, and ATM machines used by the ill persons should be disinfected. A datasheet comprising the authorised substances to disinfection in the food industry (including suspension or surface tested, kind of surface, use dilution, disinfectant and inocuylum volumes) can be seen in the supplementary material of.
VENTILATION AND AIR FILTRATION
The WHO recommends ventilation and air filtration in public spaces to help clear out infectious aerosols.
HEALTHY DIET AND LIFESTYLE
The Harvard T.H. Chan School of Public Health recommends a healthy diet, being physically active, managing psychological stress, and getting enough sleep.
While there is no evidence that vitamin D is an effective treatment for COVID-19, there is limited evidence that vitamin D deficiency increases the risk of severe COVID-19 symptoms. This has led to recommendations for individuals with vitamin D deficiency to take vitamin D supplements as a way of mitigating the risk of COVID-19 and other health issues associated with a possible increase in deficiency due to social distancing.
TREATMENT
There is no specific, effective treatment or cure for coronavirus disease 2019 (COVID-19), the disease caused by the SARS-CoV-2 virus. Thus, the cornerstone of management of COVID-19 is supportive care, which includes treatment to relieve symptoms, fluid therapy, oxygen support and prone positioning as needed, and medications or devices to support other affected vital organs.
Most cases of COVID-19 are mild. In these, supportive care includes medication such as paracetamol or NSAIDs to relieve symptoms (fever, body aches, cough), proper intake of fluids, rest, and nasal breathing. Good personal hygiene and a healthy diet are also recommended. The U.S. Centers for Disease Control and Prevention (CDC) recommend that those who suspect they are carrying the virus isolate themselves at home and wear a face mask.
People with more severe cases may need treatment in hospital. In those with low oxygen levels, use of the glucocorticoid dexamethasone is strongly recommended, as it can reduce the risk of death. Noninvasive ventilation and, ultimately, admission to an intensive care unit for mechanical ventilation may be required to support breathing. Extracorporeal membrane oxygenation (ECMO) has been used to address the issue of respiratory failure, but its benefits are still under consideration.
Several experimental treatments are being actively studied in clinical trials. Others were thought to be promising early in the pandemic, such as hydroxychloroquine and lopinavir/ritonavir, but later research found them to be ineffective or even harmful. Despite ongoing research, there is still not enough high-quality evidence to recommend so-called early treatment. Nevertheless, in the United States, two monoclonal antibody-based therapies are available for early use in cases thought to be at high risk of progression to severe disease. The antiviral remdesivir is available in the U.S., Canada, Australia, and several other countries, with varying restrictions; however, it is not recommended for people needing mechanical ventilation, and is discouraged altogether by the World Health Organization (WHO), due to limited evidence of its efficacy.
PROGNOSIS
The severity of COVID-19 varies. The disease may take a mild course with few or no symptoms, resembling other common upper respiratory diseases such as the common cold. In 3–4% of cases (7.4% for those over age 65) symptoms are severe enough to cause hospitalization. Mild cases typically recover within two weeks, while those with severe or critical diseases may take three to six weeks to recover. Among those who have died, the time from symptom onset to death has ranged from two to eight weeks. The Italian Istituto Superiore di Sanità reported that the median time between the onset of symptoms and death was twelve days, with seven being hospitalised. However, people transferred to an ICU had a median time of ten days between hospitalisation and death. Prolonged prothrombin time and elevated C-reactive protein levels on admission to the hospital are associated with severe course of COVID-19 and with a transfer to ICU.
Some early studies suggest 10% to 20% of people with COVID-19 will experience symptoms lasting longer than a month.[191][192] A majority of those who were admitted to hospital with severe disease report long-term problems including fatigue and shortness of breath. On 30 October 2020 WHO chief Tedros Adhanom warned that "to a significant number of people, the COVID virus poses a range of serious long-term effects". He has described the vast spectrum of COVID-19 symptoms that fluctuate over time as "really concerning." They range from fatigue, a cough and shortness of breath, to inflammation and injury of major organs – including the lungs and heart, and also neurological and psychologic effects. Symptoms often overlap and can affect any system in the body. Infected people have reported cyclical bouts of fatigue, headaches, months of complete exhaustion, mood swings, and other symptoms. Tedros has concluded that therefore herd immunity is "morally unconscionable and unfeasible".
In terms of hospital readmissions about 9% of 106,000 individuals had to return for hospital treatment within 2 months of discharge. The average to readmit was 8 days since first hospital visit. There are several risk factors that have been identified as being a cause of multiple admissions to a hospital facility. Among these are advanced age (above 65 years of age) and presence of a chronic condition such as diabetes, COPD, heart failure or chronic kidney disease.
According to scientific reviews smokers are more likely to require intensive care or die compared to non-smokers, air pollution is similarly associated with risk factors, and pre-existing heart and lung diseases and also obesity contributes to an increased health risk of COVID-19.
It is also assumed that those that are immunocompromised are at higher risk of getting severely sick from SARS-CoV-2. One research that looked into the COVID-19 infections in hospitalized kidney transplant recipients found a mortality rate of 11%.
See also: Impact of the COVID-19 pandemic on children
Children make up a small proportion of reported cases, with about 1% of cases being under 10 years and 4% aged 10–19 years. They are likely to have milder symptoms and a lower chance of severe disease than adults. A European multinational study of hospitalized children published in The Lancet on 25 June 2020 found that about 8% of children admitted to a hospital needed intensive care. Four of those 582 children (0.7%) died, but the actual mortality rate could be "substantially lower" since milder cases that did not seek medical help were not included in the study.
Genetics also plays an important role in the ability to fight off the disease. For instance, those that do not produce detectable type I interferons or produce auto-antibodies against these may get much sicker from COVID-19. Genetic screening is able to detect interferon effector genes.
Pregnant women may be at higher risk of severe COVID-19 infection based on data from other similar viruses, like SARS and MERS, but data for COVID-19 is lacking.
COMPLICATIONS
Complications may include pneumonia, acute respiratory distress syndrome (ARDS), multi-organ failure, septic shock, and death. Cardiovascular complications may include heart failure, arrhythmias, heart inflammation, and blood clots. Approximately 20–30% of people who present with COVID-19 have elevated liver enzymes, reflecting liver injury.
Neurologic manifestations include seizure, stroke, encephalitis, and Guillain–Barré syndrome (which includes loss of motor functions). Following the infection, children may develop paediatric multisystem inflammatory syndrome, which has symptoms similar to Kawasaki disease, which can be fatal. In very rare cases, acute encephalopathy can occur, and it can be considered in those who have been diagnosed with COVID-19 and have an altered mental status.
LONGER-TERM EFFECTS
Some early studies suggest that that 10 to 20% of people with COVID-19 will experience symptoms lasting longer than a month. A majority of those who were admitted to hospital with severe disease report long-term problems, including fatigue and shortness of breath. About 5-10% of patients admitted to hospital progress to severe or critical disease, including pneumonia and acute respiratory failure.
By a variety of mechanisms, the lungs are the organs most affected in COVID-19.[228] The majority of CT scans performed show lung abnormalities in people tested after 28 days of illness.
People with advanced age, severe disease, prolonged ICU stays, or who smoke are more likely to have long lasting effects, including pulmonary fibrosis. Overall, approximately one third of those investigated after 4 weeks will have findings of pulmonary fibrosis or reduced lung function as measured by DLCO, even in people who are asymptomatic, but with the suggestion of continuing improvement with the passing of more time.
IMMUNITY
The immune response by humans to CoV-2 virus occurs as a combination of the cell-mediated immunity and antibody production, just as with most other infections. Since SARS-CoV-2 has been in the human population only since December 2019, it remains unknown if the immunity is long-lasting in people who recover from the disease. The presence of neutralizing antibodies in blood strongly correlates with protection from infection, but the level of neutralizing antibody declines with time. Those with asymptomatic or mild disease had undetectable levels of neutralizing antibody two months after infection. In another study, the level of neutralizing antibody fell 4-fold 1 to 4 months after the onset of symptoms. However, the lack of antibody in the blood does not mean antibody will not be rapidly produced upon reexposure to SARS-CoV-2. Memory B cells specific for the spike and nucleocapsid proteins of SARS-CoV-2 last for at least 6 months after appearance of symptoms. Nevertheless, 15 cases of reinfection with SARS-CoV-2 have been reported using stringent CDC criteria requiring identification of a different variant from the second infection. There are likely to be many more people who have been reinfected with the virus. Herd immunity will not eliminate the virus if reinfection is common. Some other coronaviruses circulating in people are capable of reinfection after roughly a year. Nonetheless, on 3 March 2021, scientists reported that a much more contagious Covid-19 variant, Lineage P.1, first detected in Japan, and subsequently found in Brazil, as well as in several places in the United States, may be associated with Covid-19 disease reinfection after recovery from an earlier Covid-19 infection.
MORTALITY
Several measures are commonly used to quantify mortality. These numbers vary by region and over time and are influenced by the volume of testing, healthcare system quality, treatment options, time since the initial outbreak, and population characteristics such as age, sex, and overall health. The mortality rate reflects the number of deaths within a specific demographic group divided by the population of that demographic group. Consequently, the mortality rate reflects the prevalence as well as the severity of the disease within a given population. Mortality rates are highly correlated to age, with relatively low rates for young people and relatively high rates among the elderly.
The case fatality rate (CFR) reflects the number of deaths divided by the number of diagnosed cases within a given time interval. Based on Johns Hopkins University statistics, the global death-to-case ratio is 2.2% (2,685,770/121,585,388) as of 18 March 2021. The number varies by region. The CFR may not reflect the true severity of the disease, because some infected individuals remain asymptomatic or experience only mild symptoms, and hence such infections may not be included in official case reports. Moreover, the CFR may vary markedly over time and across locations due to the availability of live virus tests.
INFECTION FATALITY RATE
A key metric in gauging the severity of COVID-19 is the infection fatality rate (IFR), also referred to as the infection fatality ratio or infection fatality risk. This metric is calculated by dividing the total number of deaths from the disease by the total number of infected individuals; hence, in contrast to the CFR, the IFR incorporates asymptomatic and undiagnosed infections as well as reported cases.
CURRENT ESTIMATES
A December 2020 systematic review and meta-analysis estimated that population IFR during the first wave of the pandemic was about 0.5% to 1% in many locations (including France, Netherlands, New Zealand, and Portugal), 1% to 2% in other locations (Australia, England, Lithuania, and Spain), and exceeded 2% in Italy. That study also found that most of these differences in IFR reflected corresponding differences in the age composition of the population and age-specific infection rates; in particular, the metaregression estimate of IFR is very low for children and younger adults (e.g., 0.002% at age 10 and 0.01% at age 25) but increases progressively to 0.4% at age 55, 1.4% at age 65, 4.6% at age 75, and 15% at age 85. These results were also highlighted in a December 2020 report issued by the WHO.
EARLIER ESTIMATES OF IFR
At an early stage of the pandemic, the World Health Organization reported estimates of IFR between 0.3% and 1%.[ On 2 July, The WHO's chief scientist reported that the average IFR estimate presented at a two-day WHO expert forum was about 0.6%. In August, the WHO found that studies incorporating data from broad serology testing in Europe showed IFR estimates converging at approximately 0.5–1%. Firm lower limits of IFRs have been established in a number of locations such as New York City and Bergamo in Italy since the IFR cannot be less than the population fatality rate. As of 10 July, in New York City, with a population of 8.4 million, 23,377 individuals (18,758 confirmed and 4,619 probable) have died with COVID-19 (0.3% of the population).Antibody testing in New York City suggested an IFR of ~0.9%,[258] and ~1.4%. In Bergamo province, 0.6% of the population has died. In September 2020 the U.S. Center for Disease Control & Prevention reported preliminary estimates of age-specific IFRs for public health planning purposes.
SEX DIFFERENCES
Early reviews of epidemiologic data showed gendered impact of the pandemic and a higher mortality rate in men in China and Italy. The Chinese Center for Disease Control and Prevention reported the death rate was 2.8% for men and 1.7% for women. Later reviews in June 2020 indicated that there is no significant difference in susceptibility or in CFR between genders. One review acknowledges the different mortality rates in Chinese men, suggesting that it may be attributable to lifestyle choices such as smoking and drinking alcohol rather than genetic factors. Sex-based immunological differences, lesser prevalence of smoking in women and men developing co-morbid conditions such as hypertension at a younger age than women could have contributed to the higher mortality in men. In Europe, 57% of the infected people were men and 72% of those died with COVID-19 were men. As of April 2020, the US government is not tracking sex-related data of COVID-19 infections. Research has shown that viral illnesses like Ebola, HIV, influenza and SARS affect men and women differently.
ETHNIC DIFFERENCES
In the US, a greater proportion of deaths due to COVID-19 have occurred among African Americans and other minority groups. Structural factors that prevent them from practicing social distancing include their concentration in crowded substandard housing and in "essential" occupations such as retail grocery workers, public transit employees, health-care workers and custodial staff. Greater prevalence of lacking health insurance and care and of underlying conditions such as diabetes, hypertension and heart disease also increase their risk of death. Similar issues affect Native American and Latino communities. According to a US health policy non-profit, 34% of American Indian and Alaska Native People (AIAN) non-elderly adults are at risk of serious illness compared to 21% of white non-elderly adults. The source attributes it to disproportionately high rates of many health conditions that may put them at higher risk as well as living conditions like lack of access to clean water. Leaders have called for efforts to research and address the disparities. In the U.K., a greater proportion of deaths due to COVID-19 have occurred in those of a Black, Asian, and other ethnic minority background. More severe impacts upon victims including the relative incidence of the necessity of hospitalization requirements, and vulnerability to the disease has been associated via DNA analysis to be expressed in genetic variants at chromosomal region 3, features that are associated with European Neanderthal heritage. That structure imposes greater risks that those affected will develop a more severe form of the disease. The findings are from Professor Svante Pääbo and researchers he leads at the Max Planck Institute for Evolutionary Anthropology and the Karolinska Institutet. This admixture of modern human and Neanderthal genes is estimated to have occurred roughly between 50,000 and 60,000 years ago in Southern Europe.
COMORBIDITIES
Most of those who die of COVID-19 have pre-existing (underlying) conditions, including hypertension, diabetes mellitus, and cardiovascular disease. According to March data from the United States, 89% of those hospitalised had preexisting conditions. The Italian Istituto Superiore di Sanità reported that out of 8.8% of deaths where medical charts were available, 96.1% of people had at least one comorbidity with the average person having 3.4 diseases. According to this report the most common comorbidities are hypertension (66% of deaths), type 2 diabetes (29.8% of deaths), Ischemic Heart Disease (27.6% of deaths), atrial fibrillation (23.1% of deaths) and chronic renal failure (20.2% of deaths).
Most critical respiratory comorbidities according to the CDC, are: moderate or severe asthma, pre-existing COPD, pulmonary fibrosis, cystic fibrosis. Evidence stemming from meta-analysis of several smaller research papers also suggests that smoking can be associated with worse outcomes. When someone with existing respiratory problems is infected with COVID-19, they might be at greater risk for severe symptoms. COVID-19 also poses a greater risk to people who misuse opioids and methamphetamines, insofar as their drug use may have caused lung damage.
In August 2020 the CDC issued a caution that tuberculosis infections could increase the risk of severe illness or death. The WHO recommended that people with respiratory symptoms be screened for both diseases, as testing positive for COVID-19 couldn't rule out co-infections. Some projections have estimated that reduced TB detection due to the pandemic could result in 6.3 million additional TB cases and 1.4 million TB related deaths by 2025.
NAME
During the initial outbreak in Wuhan, China, the virus and disease were commonly referred to as "coronavirus" and "Wuhan coronavirus", with the disease sometimes called "Wuhan pneumonia". In the past, many diseases have been named after geographical locations, such as the Spanish flu, Middle East Respiratory Syndrome, and Zika virus. In January 2020, the WHO recommended 2019-nCov and 2019-nCoV acute respiratory disease as interim names for the virus and disease per 2015 guidance and international guidelines against using geographical locations (e.g. Wuhan, China), animal species, or groups of people in disease and virus names in part to prevent social stigma. The official names COVID-19 and SARS-CoV-2 were issued by the WHO on 11 February 2020. Tedros Adhanom explained: CO for corona, VI for virus, D for disease and 19 for when the outbreak was first identified (31 December 2019). The WHO additionally uses "the COVID-19 virus" and "the virus responsible for COVID-19" in public communications.
HISTORY
The virus is thought to be natural and of an animal origin, through spillover infection. There are several theories about where the first case (the so-called patient zero) originated. Phylogenetics estimates that SARS-CoV-2 arose in October or November 2019. Evidence suggests that it descends from a coronavirus that infects wild bats, and spread to humans through an intermediary wildlife host.
The first known human infections were in Wuhan, Hubei, China. A study of the first 41 cases of confirmed COVID-19, published in January 2020 in The Lancet, reported the earliest date of onset of symptoms as 1 December 2019.Official publications from the WHO reported the earliest onset of symptoms as 8 December 2019. Human-to-human transmission was confirmed by the WHO and Chinese authorities by 20 January 2020. According to official Chinese sources, these were mostly linked to the Huanan Seafood Wholesale Market, which also sold live animals. In May 2020 George Gao, the director of the CDC, said animal samples collected from the seafood market had tested negative for the virus, indicating that the market was the site of an early superspreading event, but that it was not the site of the initial outbreak.[ Traces of the virus have been found in wastewater samples that were collected in Milan and Turin, Italy, on 18 December 2019.
By December 2019, the spread of infection was almost entirely driven by human-to-human transmission. The number of coronavirus cases in Hubei gradually increased, reaching 60 by 20 December, and at least 266 by 31 December. On 24 December, Wuhan Central Hospital sent a bronchoalveolar lavage fluid (BAL) sample from an unresolved clinical case to sequencing company Vision Medicals. On 27 and 28 December, Vision Medicals informed the Wuhan Central Hospital and the Chinese CDC of the results of the test, showing a new coronavirus. A pneumonia cluster of unknown cause was observed on 26 December and treated by the doctor Zhang Jixian in Hubei Provincial Hospital, who informed the Wuhan Jianghan CDC on 27 December. On 30 December, a test report addressed to Wuhan Central Hospital, from company CapitalBio Medlab, stated an erroneous positive result for SARS, causing a group of doctors at Wuhan Central Hospital to alert their colleagues and relevant hospital authorities of the result. The Wuhan Municipal Health Commission issued a notice to various medical institutions on "the treatment of pneumonia of unknown cause" that same evening. Eight of these doctors, including Li Wenliang (punished on 3 January), were later admonished by the police for spreading false rumours and another, Ai Fen, was reprimanded by her superiors for raising the alarm.
The Wuhan Municipal Health Commission made the first public announcement of a pneumonia outbreak of unknown cause on 31 December, confirming 27 cases—enough to trigger an investigation.
During the early stages of the outbreak, the number of cases doubled approximately every seven and a half days. In early and mid-January 2020, the virus spread to other Chinese provinces, helped by the Chinese New Year migration and Wuhan being a transport hub and major rail interchange. On 20 January, China reported nearly 140 new cases in one day, including two people in Beijing and one in Shenzhen. Later official data shows 6,174 people had already developed symptoms by then, and more may have been infected. A report in The Lancet on 24 January indicated human transmission, strongly recommended personal protective equipment for health workers, and said testing for the virus was essential due to its "pandemic potential". On 30 January, the WHO declared the coronavirus a Public Health Emergency of International Concern. By this time, the outbreak spread by a factor of 100 to 200 times.
Italy had its first confirmed cases on 31 January 2020, two tourists from China. As of 13 March 2020 the WHO considered Europe the active centre of the pandemic. Italy overtook China as the country with the most deaths on 19 March 2020. By 26 March the United States had overtaken China and Italy with the highest number of confirmed cases in the world. Research on coronavirus genomes indicates the majority of COVID-19 cases in New York came from European travellers, rather than directly from China or any other Asian country. Retesting of prior samples found a person in France who had the virus on 27 December 2019, and a person in the United States who died from the disease on 6 February 2020.
After 55 days without a locally transmitted case, Beijing reported a new COVID-19 case on 11 June 2020 which was followed by two more cases on 12 June. By 15 June there were 79 cases officially confirmed, most of them were people that went to Xinfadi Wholesale Market.
RT-PCR testing of untreated wastewater samples from Brazil and Italy have suggested detection of SARS-CoV-2 as early as November and December 2019, respectively, but the methods of such sewage studies have not been optimised, many have not been peer reviewed, details are often missing, and there is a risk of false positives due to contamination or if only one gene target is detected. A September 2020 review journal article said, "The possibility that the COVID-19 infection had already spread to Europe at the end of last year is now indicated by abundant, even if partially circumstantial, evidence", including pneumonia case numbers and radiology in France and Italy in November and December.
MISINFORMATION
After the initial outbreak of COVID-19, misinformation and disinformation regarding the origin, scale, prevention, treatment, and other aspects of the disease rapidly spread online.
In September 2020, the U.S. CDC published preliminary estimates of the risk of death by age groups in the United States, but those estimates were widely misreported and misunderstood.
OTHER ANIMALS
Humans appear to be capable of spreading the virus to some other animals, a type of disease transmission referred to as zooanthroponosis.
Some pets, especially cats and ferrets, can catch this virus from infected humans. Symptoms in cats include respiratory (such as a cough) and digestive symptoms. Cats can spread the virus to other cats, and may be able to spread the virus to humans, but cat-to-human transmission of SARS-CoV-2 has not been proven. Compared to cats, dogs are less susceptible to this infection. Behaviors which increase the risk of transmission include kissing, licking, and petting the animal.
The virus does not appear to be able to infect pigs, ducks, or chickens at all.[ Mice, rats, and rabbits, if they can be infected at all, are unlikely to be involved in spreading the virus.
Tigers and lions in zoos have become infected as a result of contact with infected humans. As expected, monkeys and great ape species such as orangutans can also be infected with the COVID-19 virus.
Minks, which are in the same family as ferrets, have been infected. Minks may be asymptomatic, and can also spread the virus to humans. Multiple countries have identified infected animals in mink farms. Denmark, a major producer of mink pelts, ordered the slaughter of all minks over fears of viral mutations. A vaccine for mink and other animals is being researched.
RESEARCH
International research on vaccines and medicines in COVID-19 is underway by government organisations, academic groups, and industry researchers. The CDC has classified it to require a BSL3 grade laboratory. There has been a great deal of COVID-19 research, involving accelerated research processes and publishing shortcuts to meet the global demand.
As of December 2020, hundreds of clinical trials have been undertaken, with research happening on every continent except Antarctica. As of November 2020, more than 200 possible treatments had been studied in humans so far.
Transmission and prevention research
Modelling research has been conducted with several objectives, including predictions of the dynamics of transmission, diagnosis and prognosis of infection, estimation of the impact of interventions, or allocation of resources. Modelling studies are mostly based on epidemiological models, estimating the number of infected people over time under given conditions. Several other types of models have been developed and used during the COVID-19 including computational fluid dynamics models to study the flow physics of COVID-19, retrofits of crowd movement models to study occupant exposure, mobility-data based models to investigate transmission, or the use of macroeconomic models to assess the economic impact of the pandemic. Further, conceptual frameworks from crisis management research have been applied to better understand the effects of COVID-19 on organizations worldwide.
TREATMENT-RELATED RESEARCH
Repurposed antiviral drugs make up most of the research into COVID-19 treatments. Other candidates in trials include vasodilators, corticosteroids, immune therapies, lipoic acid, bevacizumab, and recombinant angiotensin-converting enzyme 2.
In March 2020, the World Health Organization (WHO) initiated the Solidarity trial to assess the treatment effects of some promising drugs: an experimental drug called remdesivir; anti-malarial drugs chloroquine and hydroxychloroquine; two anti-HIV drugs, lopinavir/ritonavir; and interferon-beta. More than 300 active clinical trials were underway as of April 2020.
Research on the antimalarial drugs hydroxychloroquine and chloroquine showed that they were ineffective at best, and that they may reduce the antiviral activity of remdesivir. By May 2020, France, Italy, and Belgium had banned the use of hydroxychloroquine as a COVID-19 treatment.
In June, initial results from the randomised RECOVERY Trial in the United Kingdom showed that dexamethasone reduced mortality by one third for people who are critically ill on ventilators and one fifth for those receiving supplemental oxygen. Because this is a well-tested and widely available treatment, it was welcomed by the WHO, which is in the process of updating treatment guidelines to include dexamethasone and other steroids. Based on those preliminary results, dexamethasone treatment has been recommended by the NIH for patients with COVID-19 who are mechanically ventilated or who require supplemental oxygen but not in patients with COVID-19 who do not require supplemental oxygen.
In September 2020, the WHO released updated guidance on using corticosteroids for COVID-19. The WHO recommends systemic corticosteroids rather than no systemic corticosteroids for the treatment of people with severe and critical COVID-19 (strong recommendation, based on moderate certainty evidence). The WHO suggests not to use corticosteroids in the treatment of people with non-severe COVID-19 (conditional recommendation, based on low certainty evidence). The updated guidance was based on a meta-analysis of clinical trials of critically ill COVID-19 patients.
WIKIPEDIA
Ipê Amarelo, Tabebuia [chrysotricha or ochracea].
Ipê-amarelo em Brasília (UnB), Brasil.
This tree is in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Found in pound water.
Full length approx 1mm.
Superdomain: Neomura
Domain: Eukaryota
(unranked): Opisthokonta
(unranked) Holozoa
(unranked) Filozoa
Kingdom: Animalia
Subkingdom: Eumetazoa
Clade: Bilateria
Clade: Nephrozoa
(unranked): Protostomia
Superphylum: Ecdysozoa
(unranked): Bilateria
Phylum: Nematoda
Class: Secernentea
Subclass: Rhabditia
Order: Rhabditida
Family: Strongyloididae
Genus: Strongyloides
Species: S. stercoralis
The growth of yellow fungus from the cut stump of a tree is not a common occurrence, but it is possible. Fungi are diverse organisms that can colonize various substrates, including decaying wood. Here are a few points to consider regarding yellow fungus growing on a tree stump:
Identification: Identifying the specific type of yellow fungus is essential because there are various species of fungi with yellow-colored fruiting bodies. Some common examples include Fuligo septica (also known as "dog vomit slime mold") and Tremella mesenterica (commonly referred to as "witches' butter"). These fungi have distinctive appearances.
Environmental Conditions: Fungi require specific environmental conditions to thrive. Yellow fungi often grow on decaying organic matter; moisture, decaying wood, and organic nutrients can contribute to their growth. A tree stump may be susceptible to fungal colonization if it provides these conditions.
Tree Health: The fungi on a tree stump may also indicate that the tree was unhealthy or already decaying before it was cut down. Fungi typically play a role in the decomposition of dead or dying trees.
Potential Issues: While some yellow fungi are harmless and primarily involved in decomposition, others can be pathogenic to plants. If you notice a yellow fungus on a tree stump in your garden or landscape, it's a good idea to monitor it and consider removing it if it seems to be spreading or causing damage to nearby vegetation.
Safety: When dealing with fungi, it's essential to take safety precautions. Some fungi can release spores that may be harmful if inhaled. Consider wearing gloves and a mask if you need to remove or handle the fungus.
If you encounter a yellow fungus growing on a tree stump and are concerned about its impact on your garden or landscape, it may be a good idea to consult with a local arborist or horticulturist who can provide specific guidance based on the situation. They can help you determine whether any action needs to be taken and how to manage the situation appropriately.
ChatGPT generated the above text. I fine-tuned it with Grammarly.
PXL_20230721_094635542
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Earth’s forces grid is made up of energies veins that distribute life throughout this crescent . It's sort of the earth's circulatory system, its network of blood vessels. It is through the energy grid that the health of the Earth is maintained.
The veins of the Earth circulate both in its depth and on its surface and excite the atmosphere, which is an integral part of the organic body of the Earth. There are main channels, which diffract in finer and denser gratings, fine grids within wide grids.
If you’re substituted the image of the veins awesome vital network of the body of the Earth is the equivalent of the nadis of the human body, and continues to keep this concept in a building, a housing environment, why not? It could be cool? Like Heaven Palast or Versailles or something for high levels….. not specifically for normal human like me 🤔
Versailles Garden is made up of subtle themes of little gardening themselves traversed by meridians and innumerable channels, the nadis (see Chakras and subtle gardens bodies). It is through these nadis that subtle energy circulates in the body’s way of the design.
The important crossroads of the nadis of the human body are energy distribution centers, the chakras. The chakras are conical or spherical volumes which cross the subtle bodies and connect the different vibratory levels of the body. Energy from the universe enters through the chakras. The body is not an isolated object adrift on Earth. It is connected to the cosmos by multiple circuits.
It is the same for the body of the Earth which is structured by its vital circuits and by crossroads of energetic flows. On some crossroads there are vortices. As we have seen (Planetary Grid), the grid is not only perceptible at the physical magnetic level, it exists on several levels dimensional. The vortices vertically cross several vibratory levels. Through its grids and vortices, the Earth is connected to the cosmos and receives impulses from the universe.
To live fully, the human being depends entirely on the good health of the terrestrial circuits. This is why in this project, a Geobiologist is assigned to the monitoring, operation and adjustment of the grids and this former industrial wasteland. The geobiologist is an engineer, guardian of sacred geometry, healers, hierophant priestess. This science is different from ours, much more subtle, deeper and more generous. She is in harmony with life, she works in harmony with it.
Regulation of flow by terrestrial acupuncture
Just as acupuncture puts the energies of our bodily meridians in order, so there is acupuncture to act on the meridians of the Earth. Earth flows are sometimes naturally chaotic, and earthly acupuncture allows them to be modified and directed. Fundamentally electrical in nature, the earth's fluxes are modulated like the electric currents in this project of housing residence.
It is the sacred constructions that serve as a needle. Menhirs strongly resemble stone needles, and this strongly suggests this function. They did fill it, at least some (Needles of Stone, Tom Grave), but not only them. We suggest to design penthouse-menhirs for location to improve the veins of the Earth.
Without necessarily being needle-shaped, other sacred centers, built according to precise geometric plans, are elaborate devices for regulating and connecting current. The set of sacred centers, temples, megaliths, simple earthworks, and ley lines, is therefore analogous to a vast printed circuit with its capacitors, transformers, transmitters and receivers.
When one detects magnetic fluxes which intersect in a sacred center of this purpose of crescent , one is tempted to deduce that the crossing existed before the construction and that it was implanted on it.
This is true, but not always. In some cases it is
the implantation of the housing itself which diverted the flow and attracted it to it according to a mastered science.
In England, John Foster Forbes was one of the first to note the links between particular engravings on the stones of a site and the constellations, or between the plan and orientation of the site and the constellations. By dowsing measurements, he realized that each of the sites vibrated according to energies related to the constellation on which it was planned. He claimed that the stone circles were built in conjunction with astronomical data to serve as a receiving station for stellar energies, at least in certain seasons.
If the sacred centers are (or were) devices of emission - reception of waves,
we can better understand that they were oriented or planned in relation to the sky and the stars. It is not to venerate the gods of these constellations but so that the place resonates with the corresponding cosmic energies. It receives cosmic energy and redistributes it to terrestrial flows, thus participating in the raising of the vibratory level and in the balancing, not only of the place itself, but of the whole circuit.
Places of healing and raising of consciousness
Another use of the grid energy was to create places for healing bodies and souls. People who are sensitive to the energy of menhirs and dolmens sometimes find that a certain stone acts in them in a certain part of the body, a certain chakra, while another stone acts on another chakra. This phenomenon is a rudimentary manifestation of a much more elaborate science using sacred geometry. In the temples (Egyptians in particular), rooms were arranged for specific healing purposes. The old centers were replaced by other cults which recovered the vibratory potentials of the places. With or without the complicity of the Christian Church, certain brotherhoods or certain orders have secretly transmitted their knowledge which has become "occult". In Europe, they knew how to use sacred geometry until the Middle Ages to build their buildings (cathedrals, abbeys, chapels, sanctuaries, calvaries). According to Georges Prat, at certain sites of ancient sacred sites or Christian sites which replaced them (England, France, etc.), the crossing of 2 or 3 metal flows is detected. In the chamber, the metallic vibrations act as the corresponding trace elements. Some places are highly beneficial due to their exceptional location where rare flows intersect. Other rooms or places are programmed to create spiritual connections with the higher planes. Their vibratory level promotes the elevation of consciousness. Each receives according to what he is, according to his faculty of reception. Staying in these places can provoke spiritual experiences, lead to
other levels of consciousness and convey information in the form of sensations, thoughts or visions. These sites also allow three-dimensional communication with the invisible for wizards and mages of all kinds, depending on the spiritual nature of the initiate and the power that is sought. Ivan Sanderson (1911 - 1973) was a biologist in the United States, but in addition he was interested in the study of strange phenomena, such as the abominable snowman and created the Society for the Investigation of the Unexplained. He also made a contribution to the study of the planetary grid in an article published in 1972 in Saga magazine: The 12 vines of the devil around the world.
He reports there the results of his investigations on the zones of terrestrial anomalies: magnetic anomalies, energetic aberrations, time distortions, disappearances of ships and planes and other strange phenomena. To collect the data and perform statistical analysis, it takes advantage of modern electronic data collection methods. It highlights 12 anomaly zones. The most astonishing is that they are equidistant and regularly arranged around the globe. Two of them are the poles and the other 10 zones are distributed on either side of the equator. The area that ranks first in these statistics is the area known as the Bermuda Triangle, east of Miami (Bahamas). It has an evil reputation because of the disappearance of planes and boats and the weather disturbances. Magnetism takes on an exceptional character: magnetic north is identical to geographic north; there are many failures of compasses, radios and control panels. This is point 18 of the Becker-Hagens grid (26 ° 36 'N 76 ° 48' W), which we will get to know later.
The Devil's Sea, in the east of Japan (point 14 of the B-H grid, 26 ° 34 'N 139 ° 12' E), located between the islands of Iwo Jima and Marcus, constitutes a second remarkable zone.
distortions, where planes and ships have gone missing. Grim events regularly take place there to the point that the Japanese government has officially classified it as a dangerous area.
Another is located near Hawaii (point 16 of grid B-H, 26 ° 34 'N 148 ° 48' W), an area of intense volcanic activity. Sanderson reports the story of a pilot whose guidance and communication instruments no longer worked in this area, and resumed working once out of the area, a failure over an area of 560 km, so for at least one half an hour maybe an hour. But the control tower recorded no interruptions, as if the crossing had lasted a second. It is a zone of time warping. Sanderson's results were taken up and developed by a group of three Russian scientists: Nikolai Goncharov is a historian, Valery Makarov is an electronics specialist, Vyacheslav Morozov is a building engineer. They add new points on the grid which take into account electromagnetic and thermal activities: magnetic and gravitational anomalies, zones of seismic fractures, ridges of underwater relief, zones of extreme climate, flights of migratory birds, sites of ancient cities. They thus arrive at a total of 62 points which include the 12 places already identified by Sanderson. In 1973, they set out their conclusions in an article entitled Is the Earth a Gigantic Crystal? published in the Soviet Science Journal Khimiya i Zhizn (Chemistry and Life). The American journalist and writer Christopher Bird made them known in a New Age Journal article published in May 1975, entitled Planetary Grid. They present a geometric network drawn on a world map. This regular network shows that a geometric structure is associated with the terrestrial sphere, either that it is superimposed on it, or that it underlies it. It is the visible imprint of an energy matrix implanted in the earth. The polyhedra that underlie the terrestrial sphere Goncharov, Makarov and Morozov noticed that the places highlighted are placed at the tops of two polyhedra which make the earth a vast crystal. Triangles are the faces of a unicosahedron and pentagons are the faces of a dodecahedron. A regular dodecahedron has 12 faces in the form of regular pentagons (dodecah = 12), 20 vertices and 30 edges. A regular icosahedron is an assembly of 20 equilateral triangles (icosa = 20) and has 12 vertices and 30 edges.
Plato's 5 regular polyhedra
The icosahedron and the dodecahedron are two of Plato's five volumes (or solids). Plato had explicitly referred to these polyhedra as symbols of the elements that make up the human body and the earth. This concept is probably very old. Kepler also attempted to put it back in honor by applying it to the solar system. Currently, they are rather known in geometry as being the only regular convex polyhedra. We say that a polyhedron is regular when its faces are regular and equal and its angles equal. Convex means that they have no hollow, unlike a star polyhedron. These polyhedra are writable in a sphere.@The other 3 Platonic solids are the octahedron and the tetrahedron, which like the icosahedron are made of triangles, and the cube, made of squares. However, we also find these three Platonic solids as an integral part of the earth grid. The cube exists in the dodecahedron itself, if we highlight some of its vertices. As David Wilcock notes, Cathie's grid reveals this cube of obvious way. Over time, the cube of the terrestrial grid could have been preexisting and then included by the dodecahedron, or the reverse, it stood out from the dodecahedron.@In Cathie's grid, we also detect the octahedron, made of 8 equilateral triangles. There remains the tetrahedron, a polyhedron with 4 triangular faces, which can also be described as a pyramid with 3 sides. Is it visible on earth?
The Earth being provided with an axis of rotation, the axis of the tetrahedron will coincide with the axis of rotation. One of the vertices of the tetrahedron is therefore on one of the poles, north or south. It follows that the base triangle will have its three vertices in the plane of a parallel, equidistant from 360/3 = 120 ° . What latitude is this parallel? If we take as a measure the side of the tetrahedron the value 1, its height, the segment which joins the vertex to the base will be 0.8165 (√6 / 3), which places the base at the latitude of 19.47 ° in the decimal system of degrees, or 19 ° 28 'in the system of degrees, minutes and seconds (sexagesimal). As the 2 poles are geometrically equivalent, we can expect to find 2 tetrahedra, one pointing upwards, the other downwards. It is a double tetrahedron, a figure brought to light by Johannes Kepler in 1609 which he named Stella Octangula, translated as a starry octangle. It is sometimes called the star tetrahedron. Its two-dimensional correspondence (on a surface) is the Star of David. Before Kepler, it was described in the Divine Proportion by Luca Pacioli, in 1509. Where are these peaks located at latitude 19 ° 47 '? The south parallel crosses the oceans, while the north parallel crosses several continents, and it is on this last that we meet 3 remarkable places.
Hawaii's volcanoes
The Big Island of Hawaii overlaps precisely this latitude, already encountered with Sanderson (point 16 of grid B-H). Its volcanoes are among the most active on earth, such as Mauna Kea located at latitude 19 ° 30 'North and longitude 155 ° West. Richard Hoagland, a former aerospace advisor for NASA, analyzed this terrestrial tetrahedron and designated Hawaii as the summit. He had started by detecting tetrahedra on other planets, Mars, Jupiter, Venus in the 1990s and had led an independent research team on lunar missions with NASA, the Pentagon and the former Soviet Union, benefiting from the data newly accessible following the lifting of defense secrecy.
The strip located on Giza
At 120 ° from Hawaii, at longitude 31 ° East, there is a whole vertical strip that runs along the Nile. According to Carl Munck (in his book The Code, 1997), all the pyramids of Egypt are located within a north-south longitudinal strip with a width of 1 °. The Nile is also contained within this strip. The great pyramid is located at latitude 30 ° North. Latitude 19 ° is lower in Sudan. According to Carl Munck, the geodesic coordinates of ancient monuments are inscribed in coded form in the monument itself. The code is quite complex and its rules seem to be the resurgence of an ancient science, gematria, the most elaborate forms of which have been lost and which remain to be rediscovered. According to this decoding, the longitudes are fixed with respect to a zero meridian which was not that of Greenwich as today, but a meridian which crosses the great pyramid of Giza. Old longitudes are deduced from current longitudes by subtracting 31 °. The great pyramid was considered the central point of the earth. Geographically, if we draw large circles passing through it, and oriented in any direction, they cross more land than can be done in no other place. It is the center of gravity of the land surface. Energetically, the place concentrates large flows of terrestrial energy. According to W. Becker (see his presentation below), the great pyramid is built on a very powerful energy point where the lines of the tetrahedron, cube, octahedron, dodecahedron and icosahedron intersect.
Energy flow grids
Apart from the statistical exploitation of geophysical data on a global scale, other discoveries were made by means of dowsing and feeling in the field in the previous article.
In the French community, the practice of energy measurements in the field by dowsing has spread widely since the 1930s with the highlighting of flows linked to megalithic sites and churches, then in the years 1950 by the dissemination of geobiology and the identification of networks, the best known of which remains the Hartmann network. Strangely enough, the reference to geobiology is generally associated with the harmfulness of certain places in a house or in a land where it is not good to stay frequently. It is a rather negative approach to vital flows which is perhaps due to the origins of its discovery by doctors.@In June 1940, a Parisian doctor, Dr Peyré, made a communication to the Academy of Sciences on his discovery of a network of North - South and East - West radiation coming from the ground. It is therefore not a question here of isolated points, nor of isolated lines intersecting each other, but of a geometric grid whose energy can be identified along the lines. Its characteristics are as follows: stitches whose side in both directions measures approx. 8 sts. George Prat, whom we will find later, identified that this network carried the radiation of copper. In a book titled Die Welt Der Geheimen Machte (1952), Siegfried Wittman states the existence of another N-S / E-W network of 16m x 16m side. He specifies that this dimension is only approximate since the N-S lines are meridians which merge at the pole and diverge towards the equator where the side of the square is 32 m. Around 1950, Dr. Manfred Curry, a German physician who worked with Wittman, discovered another telluric vibratory network (from the earth). This is oriented at 45 ° with respect to the North, therefore diagonally with respect to the Hartmann network. It is called the Curry network or diagonal net. Its average characteristics are as follows: square mesh of 3 to 16 meters with an average of 4 to 5 m in both orientations; strip thickness of about 40 centimeters. It carries the radiation of iron. It covers the whole earth. To give a realistic image, it should be noted that these values vary from one place to another. The meshes and the bands can be deformed locally. It should also be added that although it is measured on the ground, it also extends vertically like a set of thick curtains that rise from the nickel. Around 1950, another German doctor, Dr Ernst Hartmann (1925-1992) discovered almost at the same time a North-South and East-West vibratory network. Compared to the previous one, this network is tighter and its mesh is rectangular. It is called H or Hartmann network or global network. It covers the whole earth. Its mesh size is approximately 2 m (N-S) x 2 m 50 (E-O). It carries the radiation of nickel. The bands emanate from the depths of the earth and rise vertically with thicknesses of 21 cm on average. For all networks, the east-west dimension of the mesh narrows when one approaches the poles of the earth's axis (for mathematicians, proportional to the cosine of the latitude). On the other hand, the North-South distance between the parallels remains constant (see studies on this subject). Originally, the discovery of these networks is largely due to the observation that certain places are pathogenic. Certain line crossings of the network emit unfavorable energies. Normally neutral, the cross becomes pathogenic
when it carries anomalies due to the subsoil, such as certain electrical currents induced by groundwater or underground waterways, geological faults or unbalanced mineral deposits. Dr Curry and Dr Peyré have observed that harmful points of this type favor the appearance of cancer.
Metal nets by Georges Prat
We have already met Georges Prat, French architect and geobiologist. By doing his expertise in the field, he finds the networks previously named. But he discovers many others that vibrate differently. Seeking to understand their nature, he enlists the collaboration of an Austrian researcher who measures the radiation of the network by means of a scientific laboratory apparatus, and he identifies the radiation of these networks with metals (we unfortunately do not know with what apparatus the now deceased researcher proceeded, nor what type of measurement he carried out. However, the results can be verified retrospectively by dowsing). This is how Pratt identifies the Hartmann network with nickel, the Curry network with iron and the Peyré network with copper. According to him, the radiations coming from the center of the Earth do not come to us uniformly but in the form of networks of energy, like the meshes of a net ... Each metal has its own mesh whose dimensions depend on its quantitative importance. inside our own planet. Thus nickel, a widespread and abundant metal in the central core of the Earth, has a net of 2 meters by 2.5 m in European latitudes, while gold, the rarest metal, is not found under the same conditions as every 400 km (555 km at the equator). (G. Prat, Cartesian Precise of Geobiology)
sc7467ceb46111604.jimcontent.com/download/version/1416597...
Each mesh is unique in terms of the size and orientation of the mesh. For example, the network of nickel (Hartmann) is rectangular and the tightest of the networks. The meshes are delimited by vertical walls or curtains which rise in height and also have a determined thickness. Prat also highlighted the networks of cobalt, manganese, platinum, uranium, selenium, palladium, lithium, magnesium, antimony, titanium, siderite ... These flows are rarer. They are sometimes found in certain Neolithic temples where the crossing of several of them acts as a place of healing by trace elements.@Another remarkable feature of all metal mesh is that
the thickness of the vertical wall is doubled every 9 meshes. We can therefore consider that a network is "structured" by another network of the same nature, larger and more powerful.
The networks of platinum, silver and gold have very wide meshes, so that few of them are found on earth. Thus the platinum network has only 38 meridians cut by 36 parallels. Double networks are even rarer. That of gold includes only 3 circles from north to south, one of which is the equator and the other 2 parallels of either side of the equator. In the East-West direction, there are 4 large circles (ie 8 meridians). In total, they determine 26 crossing points. Gold and silver network in Europe and North Africa Thanks to G. Prat (© Précis Cartesien de géobiologie)
The silver network is coupled with that of gold. Although they are oriented differently, their crossing points are superimposed. It is the same with the networks of double silver and double gold. Thus, the 26 crossing points of double gold are also those of double silver.. This makes these points remarkable sites. Most of these crosses are located in inaccessible places or in the ocean. Only two are accessible and marked as high places: Chartres Cathedral in France and Potala Palace in Tibet. The crossing points of simple gold are also of great interest. It is on these points that the oldest temples are installed, often subsequently replaced by other temples and then by churches or cathedrals. The flow of lines of the eastern network connect famous centers: Moscow, Istanbul and Giza; Chartres, Toulouse and Ghardaia. Ghardaïa, in Algeria, considered as a tourist site of major importance because of its architecture and its history, is part of the world heritage. The synthesis of this information from various sources puts us in front of several energy flow systems of the earth. On the one hand, the location of geomagnetic anomalies led to the identification of the 120 polyhedron with its 62
points and its triangles. The lines are represented at first glance as geometric traces between the vertices, not as energy flows, although they probably are, as the existence of leys lines suggests to us almost everywhere on earth. On the other hand, the experimental measurements in dowsing reveal bundles of lines and grids of energy flows which cover the whole planet.
From these findings, questions may come to mind. The double gold lattice closely resembles the Sanderson grid and the Becker-Hagens grid but is different. Is there a relationship between them and which one? Why do some points on the Becker-Hagens geometric grid seem to be offset from a nearby sacred place? I will try to give answers to these questions insofar as it can open our minds to the reality of these grids. However, I will not try to answer with precise technical data which would require lengthy and unnecessary investigations. The aim of this article is to raise awareness of the existence and operation of the grid, even if we do not fully know how it is constituted. Kind of like you can benefit from a computer without knowing exactly its internal structure. I stay focused on my goal of understanding who we are and how we relate to the universe. Here are a few more concepts that take into account the complexity of grids. There is not a single grid, but several that are superimposed and connected; they do not follow a strict geometry like a computer drawing; they are alive, moving and adaptable. Our discovery of metal networks illustrates the fact that several networks, several grids coexist and interpenetrate. Each carries a different energy and therefore has a specific function. There are great grids which are the main life conduits of the earth. These large meshes are divided into smaller meshes, themselves subdivided into even smaller meshes creating a finer mesh. There are grids within grids, according to a hierarchy of scale that can be described as fractal. We can compare this interweaving of networks to the vital networks of the human body. The blood system is strongly coupled to the respiratory network, the lymphatic system and the nervous system, for example. It is itself made up of large main vessels, which branch out into finer vessels, and even up to the extremely fine capillary vessels.
In addition, the human body is made of the superposition of at least 5 energy bodies of different vibratory levels: physical, vital, emotional, mental and spiritual body (see article Chakras and subtle bodies). It is the same for the Earth. She has her own energy bodies. So the comparison between the human body and the body of the Earth is not just a convenient picture. It is a reality: the human body and the terrestrial body are constituted according to similar structures. Each body on Earth has its own circulatory system: it is a grid. The multidimensional superposition of grids has for example been described by Richard Leviton (Leys lines and the meaning of Adam). According to his vision, a certain form of energy structure was put in place in the early days of Earth's existence, in relation to the appearance of biological life. The original structure was made of straight lines connecting energy vortices in the form of domes posed on the surface of the earth. These lines were double, one carrying the vibration of gold and the other that of silver. These lines went up too vertically in a way to meet at a particular point on Earth, its navel in a way. That navel could be Avebury in England. It is interesting to note that other places on the planet have been named navel, such as the umphalos of Delphi in Greece or Cuzco in Peru. Levinton distinguishes 4 grids of different vibratory levels, corresponding to the energetic bodies of the Earth, located on the surface or in the atmosphere, up to approximately 3 km of altitude. One of them is made of 15 large circles surrounding the
earth above its surface, determining 62 crossing points and 120 triangles. The St. Michael's ley line in England is one of them. It is not limited to England, it goes around the world. Another grid, often parallel to the previous one, includes a multitude of secondary domes, in total 1746 domes which have become potential places of menhirs, megalithic centers or temples. Each dome carried the codes of light necessary to create life. Thus, the vital flows of the earth are distributed according to a system of multidimensional geometric grids whose structure is based on a combination of polyhedra inscribed in the terrestrial sphere, the Platonic solids and their fractal derivatives. However, these geometries are not immutable. The grids are alive and like any living being, they breathe and evolve. Their evolution is linked to
the evolution of the earth and of humanity. According to Levinton, every major change in the evolution of biological and human life has been accompanied by a change in the structure of the grids, for example at the time of the appearance of man on Earth. According to other authors, important modifications of the grids marked the beginning of the human experience of duality, that is to say the cut of man with his inner divine being and with the celestial hierarchies. But here we are again faced with strong modifications of the grids which have disturbing repercussions on our bodies and our minds, as well as on geology.
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Three young mushrooms; probably Armillaria limonea
Information from www.terrain.net.nz/friends-of-te-henui-group/fungi-te-hen....
"Armillaria limonea is a species of mushroom in the Physalacriaceae family. This plant pathogenic species is one of three Armillaria that have been identified in New Zealand (the others are A. novae-zelandiae and A. hinnulea). It is interesting that the hyphae (vegetative part) of Armillaria spp are bioluminescent and decaying logs may be seen glowing faintly in indigenous forests on dark nights.
Armillaria spp. are widespread in New Zealand and occur naturally in indigenous forests, both beech and podocarp/broadleaf. Fruiting bodies are produced between May and July and its cap (80mm), is dry with a sprinkling of tiny black granules, lemon yellow or creamy white. The gills are white; ring present; stalk light-brown, tapering towards the cap, with a bulbous base (height: 10 mm). They are found on rotten logs, snags, or other decaying debris, and may occur singly, in dense clusters, or in groups which can be up to 5 m wide."
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].
Ipê Amarelo, Tabebuia [chrysotricha ou ochracea].
Ipê-amarelo perto do Parque da Cidade, em Brasília, Brasil.
This tree is near the Brasília's City's Park
, in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Naturgetreue Abblidungen und Beschreibungen der essbaren, schädlichen und verdächtigen Schwämme /
Prag :In Commission in der J. G. Calve'schen Buchhandlung,1831-1846.
Imaging bio-molecules and cells over extended periods of time is critical to understanding cellular processes and the causes of pathogenic diseases. Cadmium sulfide quantum dots are widely used for highly sensitive cellular imaging. The extraordinary photostability of these probes are highly attractive for the real-time tracking of bio-molecules and cells over time. PNNL scientists are exploring quantum dots with varying morphologies and trying to understand the variation of their spectroscopy associated with the morphological changes. The goal is to design probes that can be used to monitor cellular processes over extended periods. PNNL researcher Dev Chatterjee provided the image. Others who contribute to the project include Matthew Edwards, Paul MacFarlan, Samuel Bryan and Jason Hoki. Image colored by PNNL graphic designer Jeff London.
This image was a part of the 2011 PNNL Science as Art contest.
Terms of Use: Our images are freely and publicly available for use with the credit line, "Courtesy of Pacific Northwest National Laboratory." Please use provided caption information for use in appropriate context.
Ipê Amarelo, Tabebuia [chrysotricha or ochracea].
Ipê-amarelo em Brasília (UnB), Brasil.
This tree is in Brasília, Capital of Brazil.
Text, in english, from Wikipedia, the free encyclopedia
"Trumpet tree" redirects here. This term is occasionally used for the Shield-leaved Pumpwood (Cecropia peltata).
Tabebuia
Flowering Araguaney or ipê-amarelo (Tabebuia chrysantha) in central Brazil
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Lamiales
Family: Bignoniaceae
Tribe: Tecomeae
Genus: Tabebuia
Gomez
Species
Nearly 100.
Tabebuia is a neotropical genus of about 100 species in the tribe Tecomeae of the family Bignoniaceae. The species range from northern Mexico and the Antilles south to northern Argentina and central Venezuela, including the Caribbean islands of Hispaniola (Dominican Republic and Haiti) and Cuba. Well-known common names include Ipê, Poui, trumpet trees and pau d'arco.
They are large shrubs and trees growing to 5 to 50 m (16 to 160 ft.) tall depending on the species; many species are dry-season deciduous but some are evergreen. The leaves are opposite pairs, complex or palmately compound with 3–7 leaflets.
Tabebuia is a notable flowering tree. The flowers are 3 to 11 cm (1 to 4 in.) wide and are produced in dense clusters. They present a cupular calyx campanulate to tubular, truncate, bilabiate or 5-lobed. Corolla colors vary between species ranging from white, light pink, yellow, lavender, magenta, or red. The outside texture of the flower tube is either glabrous or pubescentThe fruit is a dehiscent pod, 10 to 50 cm (4 to 20 in.) long, containing numerous—in some species winged—seeds. These pods often remain on the tree through dry season until the beginning of the rainy.
Species in this genus are important as timber trees. The wood is used for furniture, decking, and other outdoor uses. It is increasingly popular as a decking material due to its insect resistance and durability. By 2007, FSC-certified ipê wood had become readily available on the market, although certificates are occasionally forged.
Tabebuia is widely used as ornamental tree in the tropics in landscaping gardens, public squares, and boulevards due to its impressive and colorful flowering. Many flowers appear on still leafless stems at the end of the dry season, making the floral display more conspicuous. They are useful as honey plants for bees, and are popular with certain hummingbirds. Naturalist Madhaviah Krishnan on the other hand once famously took offense at ipé grown in India, where it is not native.
Lapacho teaThe bark of several species has medical properties. The bark is dried, shredded, and then boiled making a bitter or sour-tasting brownish-colored tea. Tea from the inner bark of Pink Ipê (T. impetiginosa) is known as Lapacho or Taheebo. Its main active principles are lapachol, quercetin, and other flavonoids. It is also available in pill form. The herbal remedy is typically used during flu and cold season and for easing smoker's cough. It apparently works as expectorant, by promoting the lungs to cough up and free deeply embedded mucus and contaminants. However, lapachol is rather toxic and therefore a more topical use e.g. as antibiotic or pesticide may be advisable. Other species with significant folk medical use are T. alba and Yellow Lapacho (T. serratifolia)
Tabebuia heteropoda, T. incana, and other species are occasionally used as an additive to the entheogenic drink Ayahuasca.
Mycosphaerella tabebuiae, a plant pathogenic sac fungus, was first discovered on an ipê tree.
Tabebuia alba
Tabebuia anafensis
Tabebuia arimaoensis
Tabebuia aurea – Caribbean Trumpet Tree
Tabebuia bilbergii
Tabebuia bibracteolata
Tabebuia cassinoides
Tabebuia chrysantha – Araguaney, Yellow Ipê, tajibo (Bolivia), ipê-amarelo (Brazil), cañaguate (N Colombia)
Tabebuia chrysotricha – Golden Trumpet Tree
Tabebuia donnell-smithii Rose – Gold Tree, "Prima Vera", Cortez blanco (El Salvador), San Juan (Honduras), palo blanco (Guatemala),duranga (Mexico)
A native of Mexico and Central Americas, considered one of the most colorful of all Central American trees. The leaves are deciduous. Masses of golden-yellow flowers cover the crown after the leaves are shed.
Tabebuia dubia
Tabebuia ecuadorensis
Tabebuia elongata
Tabebuia furfuracea
Tabebuia geminiflora Rizz. & Mattos
Tabebuia guayacan (Seem.) Hemsl.
Tabebuia haemantha
Tabebuia heptaphylla (Vell.) Toledo – tajy
Tabebuia heterophylla – roble prieto
Tabebuia heteropoda
Tabebuia hypoleuca
Tabebuia impetiginosa – Pink Ipê, Pink Lapacho, ipê-cavatã, ipê-comum, ipê-reto, ipê-rosa, ipê-roxo-damata, pau d'arco-roxo, peúva, piúva (Brazil), lapacho negro (Spanish); not "brazilwood"
Tabebuia incana
Tabebuia jackiana
Tabebuia lapacho – lapacho amarillo
Tabebuia orinocensis A.H. Gentry[verification needed]
Tabebuia ochracea
Tabebuia oligolepis
Tabebuia pallida – Cuban Pink Trumpet Tree
Tabebuia platyantha
Tabebuia polymorpha
Tabebuia rosea (Bertol.) DC.[verification needed] (= T. pentaphylla (L.) Hemsley) – Pink Poui, Pink Tecoma, apama, apamate, matilisguate
A popular street tree in tropical cities because of its multi-annular masses of light pink to purple flowers and modest size. The roots are not especially destructive for roads and sidewalks. It is the national tree of El Salvador and the state tree of Cojedes, Venezuela
Tabebuia roseo-alba – White Ipê, ipê-branco (Brazil), lapacho blanco
Tabebuia serratifolia – Yellow Lapacho, Yellow Poui, ipê-roxo (Brazil)
Tabebuia shaferi
Tabebuia striata
Tabebuia subtilis Sprague & Sandwith
Tabebuia umbellata
Tabebuia vellosoi Toledo
Ipê-do-cerrado
Texto, em português, da Wikipédia, a enciclopédia livre.
Ipê-do-cerrado
Classificação científica
Reino: Plantae
Divisão: Magnoliophyta
Classe: Magnoliopsida
Subclasse: Asteridae
Ordem: Lamiales
Família: Bignoniaceae
Género: Tabebuia
Espécie: T. ochracea
Nome binomial
Tabebuia ochracea
(Cham.) Standl. 1832
Sinónimos
Bignonia tomentosa Pav. ex DC.
Handroanthus ochraceus (Cham.) Mattos
Tabebuia chrysantha (Jacq.) G. Nicholson
Tabebuia hypodictyon A. DC.) Standl.
Tabebuia neochrysantha A.H. Gentry
Tabebuia ochracea subsp. heteropoda (A. DC.) A.H. Gentry
Tabebuia ochracea subsp. neochrysantha (A.H. Gentry) A.H. Gentry
Tecoma campinae Kraenzl.
ecoma grandiceps Kraenzl.
Tecoma hassleri Sprague
Tecoma hemmendorffiana Kraenzl.
Tecoma heteropoda A. DC.
Tecoma hypodictyon A. DC.
Tecoma ochracea Cham.
Ipê-do-cerrado é um dos nomes populares da Tabebuia ochracea (Cham.) Standl. 1832, nativa do cerrado brasileiro, no estados de Amazonas, Pará, Maranhão, Piauí, Ceará, Pernambuco, Bahia, Espírito Santo, Goiás, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Rio de Janeiro, São Paulo e Paraná.
Está na lista de espécies ameaçadas do estado de São Paulo, onde é encontrda também no domínio da Mata Atlântica[1].
Ocorre também na Argentina, Paraguai, Bolívia, Equador, Peru, Venezuela, Guiana, El Salvador, Guatemala e Panamá[2].
Há uma espécie homônima descrita por A.H. Gentry em 1992.
Outros nomes populares: ipê-amarelo, ipê-cascudo, ipê-do-campo, ipê-pardo, pau-d'arco-do-campo, piúva, tarumã.
Características
Altura de 6 a 14 m. Tronco tortuso com até 50 cm de diâmetro. Folhas pilosas em ambas as faces, mais na inferior, que é mais clara.
Planta decídua, heliófita, xerófita, nativa do cerrado em solos bem drenados.
Floresce de julho a setembro. Os frutos amadurecem de setembro a outubro.
FloresProduz grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em menos de 90 dias após coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978). As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A germinação ocorre após 30 dias e de 80%. As sementes são ortodoxas e há aproximadamente 72 000 sementes em cada quilo.
O desenvolvimento da planta é rápido.
Como outros ipês, a madeira é usada em tacos, assoalhos, e em dormentes e postes. Presta-se também para peças torneadas e instrumento musicais.
Tabebuia alba (Ipê-Amarelo)
Texto, em português, produzido pela Acadêmica Giovana Beatriz Theodoro Marto
Supervisão e orientação do Prof. Luiz Ernesto George Barrichelo e do Eng. Paulo Henrique Müller
Atualizado em 10/07/2006
O ipê amarelo é a árvore brasileira mais conhecida, a mais cultivada e, sem dúvida nenhuma, a mais bela. É na verdade um complexo de nove ou dez espécies com características mais ou menos semelhantes, com flores brancas, amarelas ou roxas. Não há região do país onde não exista pelo menos uma espécie dele, porém a existência do ipê em habitat natural nos dias atuais é rara entre a maioria das espécies (LORENZI,2000).
A espécie Tabebuia alba, nativa do Brasil, é uma das espécies do gênero Tabebuia que possui “Ipê Amarelo” como nome popular. O nome alba provém de albus (branco em latim) e é devido ao tomento branco dos ramos e folhas novas.
As árvores desta espécie proporcionam um belo espetáculo com sua bela floração na arborização de ruas em algumas cidades brasileiras. São lindas árvores que embelezam e promovem um colorido no final do inverno. Existe uma crença popular de que quando o ipê-amarelo floresce não vão ocorrer mais geadas. Infelizmente, a espécie é considerada vulnerável quanto à ameaça de extinção.
A Tabebuia alba, natural do semi-árido alagoano está adaptada a todas as regiões fisiográficas, levando o governo, por meio do Decreto nº 6239, a transformar a espécie como a árvore símbolo do estado, estando, pois sob a sua tutela, não mais podendo ser suprimida de seus habitats naturais.
Taxonomia
Família: Bignoniaceae
Espécie: Tabebuia Alba (Chamiso) Sandwith
Sinonímia botânica: Handroanthus albus (Chamiso) Mattos; Tecoma alba Chamisso
Outros nomes vulgares: ipê-amarelo, ipê, aipê, ipê-branco, ipê-mamono, ipê-mandioca, ipê-ouro, ipê-pardo, ipê-vacariano, ipê-tabaco, ipê-do-cerrado, ipê-dourado, ipê-da-serra, ipezeiro, pau-d’arco-amarelo, taipoca.
Aspectos Ecológicos
O ipê-amarelo é uma espécie heliófita (Planta adaptada ao crescimento em ambiente aberto ou exposto à luz direta) e decídua (que perde as folhas em determinada época do ano). Pertence ao grupo das espécies secundárias iniciais (DURIGAN & NOGUEIRA, 1990).
Abrange a Floresta Pluvial da Mata Atlântica e da Floresta Latifoliada Semidecídua, ocorrendo principalmente no interior da Floresta Primária Densa. É característica de sub-bosques dos pinhais, onde há regeneração regular.
Informações Botânicas
Morfologia
As árvores de Tabebuia alba possuem cerca de 30 metros de altura. O tronco é reto ou levemente tortuoso, com fuste de 5 a 8 m de altura. A casca externa é grisáceo-grossa, possuindo fissuras longitudinais esparas e profundas. A coloração desta é cinza-rosa intenso, com camadas fibrosas, muito resistentes e finas, porém bem distintas.
Com ramos grossos, tortuosos e compridos, o ipê-amarelo possui copa alongada e alargada na base. As raízes de sustentação e absorção são vigorosas e profundas.
As folhas, deciduais, são opostas, digitadas e compostas. A face superior destas folhas é verde-escura, e, a face inferior, acinzentada, sendo ambas as faces tomentosas. Os pecíolos das folhas medem de 2,5 a 10 cm de comprimento. Os folíolos, geralmente, apresentam-se em número de 5 a 7, possuindo de 7 a 18 cm de comprimento por 2 a 6 cm de largura. Quando jovem estes folíolos são densamente pilosos em ambas as faces. O ápice destes é pontiagudo, com base arredondada e margem serreada.
As flores, grandes e lanceoladas, são de coloração amarelo-ouro. Possuem em média 8X15 cm.
Quanto aos frutos, estes possuem forma de cápsula bivalvar e são secos e deiscentes. Do tipo síliqua, lembram uma vagem. Medem de 15 a 30 cm de comprimento por 1,5 a 2,5 cm de largura. As valvas são finamente tomentosas com pêlos ramificados. Possuem grande quantidade de sementes.
As sementes são membranáceas brilhantes e esbranquiçadas, de coloração marrom. Possuem de 2 a 3 cm de comprimento por 7 a 9 mm de largura e são aladas.
Reprodução
A espécie é caducifólia e a queda das folhas coincide com o período de floração. A floração inicia-se no final de agosto, podendo ocorrer alguma variação devido a fenômenos climáticos. Como a espécie floresce no final do inverno é influenciada pela intensidade do mesmo. Quanto mais frio e seco for o inverno, maior será a intensidade da florada do ipê amarelo.
As flores por sua exuberância, atraem abelhas e pássaros, principalmente beija-flores que são importantes agentes polinizadores. Segundo CARVALHO (2003), a espécie possui como vetor de polinização a abelha mamangava (Bombus morio).
As sementes são dispersas pelo vento.
A planta é hermafrodita, e frutifica nos meses de setembro, outubro, novembro, dezembro, janeiro e fevereiro, dependendo da sua localização. Em cultivo, a espécie inicia o processo reprodutivo após o terceiro ano.
Ocorrência Natural
Ocorre naturalmente na Floresta Estaciobal Semidecicual, Floresta de Araucária e no Cerrado.
Segundo o IBGE, a Tabebuia alba (Cham.) Sandw. é uma árvore do Cerrado, Cerradão e Mata Seca. Apresentando-se nos campos secos (savana gramíneo-lenhosa), próximo às escarpas.
Clima
Segundo a classificação de Köppen, o ipê-amarelo abrange locais de clima tropical (Aw), subtropical úmido (Cfa), sutropical de altitude (Cwa e Cwb) e temperado.
A T.alba pode tolerar até 81 geadas em um ano. Ocorre em locais onde a temperatura média anual varia de 14,4ºC como mínimo e 22,4ºC como máximo.
Solo
A espécie prefere solos úmidos, com drenagem lenta e geralmente não muito ondulados (LONGHI, 1995).
Aparece em terras de boa à média fertilidade, em solos profundos ou rasos, nas matas e raramente cerradões (NOGUEIRA, 1977).
Pragas e Doenças
De acordo com CARVALHO (2003), possui como praga a espécie de coleópteros Cydianerus bohemani da família Curculionoideae e um outro coleóptero da família Chrysomellidae. Apesar da constatação de elevados índices populacionais do primeiro, os danos ocasionados até o momento são leves. Nas praças e ruas de Curitiba - PR, 31% das árvores foram atacadas pela Cochonilha Ceroplastes grandis.
ZIDKO (2002), ao estudar no município de Piracicaba a associação de coleópteros em espécies arbóreas, verificou a presença de insetos adultos da espécie Sitophilus linearis da família de coleópteros, Curculionidae, em estruturas reprodutivas. Os insetos adultos da espécie emergiram das vagens do ipê, danificando as sementes desta espécie nativa.
ANDRADE (1928) assinalou diversas espécies de Cerambycidae atacando essências florestais vivas, como ingazeiro, cinamomo, cangerana, cedro, caixeta, jacarandá, araribá, jatobá, entre outras como o ipê amarelo.
A Madeira
A Tabebuia alba produz madeira de grande durabilidade e resistência ao apodrecimento (LONGHI,1995).
MANIERI (1970) caracteriza o cerne desta espécie como de cor pardo-havana-claro, pardo-havan-escuro, ou pardo-acastanhado, com reflexos esverdeados. A superfície da madeira é irregularmente lustrosa, lisa ao tato, possuindo textura media e grã-direita.
Com densidade entre 0,90 e 1,15 grama por centímetro cúbico, a madeira é muito dura (LORENZI, 1992), apresentando grande dificuldade ao serrar.
A madeira possui cheiro e gosto distintos. Segundo LORENZI (1992), o cheiro característico é devido à presença da substância lapachol, ou ipeína.
Usos da Madeira
Sendo pesada, com cerne escuro, adquire grande valor comercial na marcenaria e carpintaria. Também é utilizada para fabricação de dormentes, moirões, pontes, postes, eixos de roda, varais de carroça, moendas de cana, etc.
Produtos Não-Madeireiros
A entrecasca do ipê-amarelo possui propriedades terapêuticas como adstringente, usada no tratamento de garganta e estomatites. É também usada como diurético.
O ipê-amarelo possui flores melíferas e que maduras podem ser utilizadas na alimentação humana.
Outros Usos
É comumente utilizada em paisagismo de parques e jardins pela beleza e porte. Além disso, é muito utilizada na arborização urbana.
Segundo MOREIRA & SOUZA (1987), o ipê-amarelo costuma povoar as beiras dos rios sendo, portanto, indicado para recomposição de matas ciliares. MARTINS (1986), também cita a espécie para recomposição de matas ciliares da Floresta Estacional Semidecidual, abrangendo alguns municípios das regiões Norte, Noroeste e parte do Oeste do Estado do Paraná.
Aspectos Silviculturais
Possui a tendência a crescer reto e sem bifurcações quando plantado em reflorestamento misto, pois é espécie monopodial. A desrrama se faz muito bem e a cicatrização é boa. Sendo assim, dificilmente encopa quando nova, a não ser que seja plantado em parques e jardins.
Ao ser utilizada em arborização urbana, o ipê amarelo requer podas de condução com freqüência mediana.
Espécie heliófila apresenta a pleno sol ramificação cimosa, registrando-se assim dicotomia para gema apical. Deve ser preconizada, para seu melhor aproveitamento madeireiro, podas de formação usuais (INQUE et al., 1983).
Produção de Mudas
A propagação deve realizada através de enxertia.
Os frutos devem ser coletados antes da dispersão, para evitar a perda de sementes. Após a coleta as sementes são postas em ambiente ventilado e a extração é feita manualmente. As sementes do ipê amarelo são ortodoxas, mantendo a viabilidade natural por até 3 meses em sala e por até 9 meses em vidro fechado, em câmara fria.
A condução das mudas deve ser feita a pleno sol. A muda atinge cerca de 30 cm em 9 meses, apresentando tolerância ao sol 3 semanas após a germinação.
Sementes
Os ipês, espécies do gênero Tabebuia, produzem uma grande quantidade de sementes leves, aladas com pequenas reservas, e que perdem a viabilidade em poucos dias após a sua coleta. A sua conservação vem sendo estudada em termos de determinação da condição ideal de armazenamento, e tem demonstrado a importância de se conhecer o comportamento da espécie quando armazenada com diferentes teores de umidade inicial, e a umidade de equilíbrio crítica para a espécie (KANO; MÁRQUEZ & KAGEYAMA, 1978).
As levíssimas sementes aladas da espécie não necessitam de quebra de dormência. Podem apenas ser expostas ao sol por cerca de 6 horas e semeadas diretamente nos saquinhos. A quebra natural leva cerca de 3 meses e a quebra na câmara leva 9 meses. A germinação ocorre após 30 dias e de 80%.
As sementes são ortodoxas e há aproximadamente 87000 sementes em cada quilo.
Preço da Madeira no Mercado
O preço médio do metro cúbico de pranchas de ipê no Estado do Pará cotado em Julho e Agosto de 2005 foi de R$1.200,00 o preço mínimo, R$ 1509,35 o médio e R$ 2.000,00 o preço máximo (CEPEA,2005).
Naturgetreue Abblidungen und Beschreibungen der essbaren, schädlichen und verdächtigen Schwämme /
Prag :In Commission in der J. G. Calve'schen Buchhandlung,1831-1846.
Naturgetreue Abblidungen und Beschreibungen der essbaren, schädlichen und verdächtigen Schwämme /
Prag :In Commission in der J. G. Calve'schen Buchhandlung,1831-1846.
Sveriges ätliga och giftiga svampar tecknade efter naturen under ledning /.
Stockholm :P.A. Norstedt & söner kongl. boktryckare,1861-[69].