1. Malaria in pregnancy alters l-arginine bioavailability and placental vascular development.

Reducing adverse birth outcomes due to malaria in pregnancy (MIP) is a global health priority. However, there are few safe and effective interventions. L-Arginine is an essential amino acid in pregnancy...

www.bioadvisers.com/pet-imaging-approach-determining-egfr...

The long awaited harvest season has finally arrived, and with it some beautiful regionally grown heritage wheat varieties that we have eagerly been awaiting the last few months. These golden, buttery Khorasan grains have been slowly sprouting over the last few days and are gently drying to be milled into fresh flour tomorrow morning. All my grains are sprouted first, to wake up the sleeping enzymes, reduce phytic acid and make the nourishment they carry within bioavailable for easy absorption by our digestive systems. The incredible chemical changes that occur during the long fermentation process allow our bodies to digest this type of living flour very differently than conventional flour (using enzymes like those used for digesting vegetables as opposed to starches) and lowering the gluten levels significantly in the end result, all of which makes sprouted sourdough that has been long fermented not only full of minerals and other nutrients that we can easily absorb, but allows us to nourish our microbiome and enables the ease of digesting sprouted sourdough bread that has been properly prepared.

#sourdough #fermentation #sourdoughbread #wholefoods #nourishingtraditions #realbread #slowfood #feedingmyfamily #nourishingfoods #nutrition #naturallyleavened #eatrealfood #fermentedfoods #dutchoven #spelt #sproutedbread #sproutedflour #carbs #gluten #guthealth #digestion #enzymes #brot #flourwatersalt #lactobacillus #bacterialcultures #ferment #khorasan #sourdoughclub

The long awaited harvest season has finally arrived, and with it some beautiful regionally grown heritage wheat varieties that we have eagerly been awaiting the last few months. These golden, buttery Khorasan grains have been slowly sprouting over the last few days and are gently drying to be milled into fresh flour tomorrow morning. All my grains are sprouted first, to wake up the sleeping enzymes, reduce phytic acid and make the nourishment they carry within bioavailable for easy absorption by our digestive systems. The incredible chemical changes that occur during the long fermentation process allow our bodies to digest this type of living flour very differently than conventional flour (using enzymes like those used for digesting vegetables as opposed to starches) and lowering the gluten levels significantly in the end result, all of which makes sprouted sourdough that has been long fermented not only full of minerals and other nutrients that we can easily absorb, but allows us to nourish our microbiome and enables the ease of digesting sprouted sourdough bread that has been properly prepared.

#sourdough #fermentation #sourdoughbread #wholefoods #nourishingtraditions #realbread #slowfood #feedingmyfamily #nourishingfoods #nutrition #naturallyleavened #eatrealfood #fermentedfoods #dutchoven #spelt #sproutedbread #sproutedflour #carbs #gluten #guthealth #digestion #enzymes #brot #flourwatersalt #lactobacillus #bacterialcultures #ferment #khorasan #sourdoughclub

Living Water Works is your agricultural irrigation systems company in Mountain Home, Idaho. Foremost, we are a national company that engineers and builds water revitalization systems; from small to large irrigation and industrial applications. In addition, Living Water Works is a distribution company for Verity Water units for the home and business use. We introduce you to a patented science that uses quantum physics to ignite the power of water. Your body is made up of 90% water according to recent studies so the most important calculation for the preservation of your health is the quality of your water. When water is transformed from hard water or toxic water, or dead water to “living water” it becomes highly bioavailable to the cells of your body. We offer a 90 day satisfaction guarantee and a 2 year guarantee for replacement of the device due to faulty workmanship. There are no parts that need replacing. For large irrigation systems and industrial applications we offer a 1 year satisfaction guarantee. We provide service to our customers in the area of Mountain Home, Idaho.

A story about grain 🌾 as promised. Sprouting your grains is critical before milling into flour for max absorption of nutrients, the best flavour and has a significant impact on how digestible your bread is. Wheat kernels are compromised of three parts: the Endosperm (starch + protein), the germ (nutrient rich storehouse of antioxidants, healthy fats and vitamins E, B) and the bran (rich in fibre, minerals, phytochemicals). The wheat kernel, much like the vegetable seeds you plant in the garden, is dormant and the nutrition in it not available for absorption. Not only are all the beautiful nutrients in the grain not available to us if milled in the unsprouted state, it actually has negative consequences when digested- phytic acid binds with/removes minerals from our body, and inhibits the digestibility of starch and protein. It also has high levels of tannins which give the flour a slightly bitter taste. Sprouting activates enzymes that break down phytic acid (humans do not have the phytase enzyme in their gut necessary to process phytic acid), and awaken the sleeping, nutrition rich storehouses of antioxidants, fats, fibre, minerals and vitamins, making these nutrients bioavailable for our bodies to absorb. The enzymes break down starch, converting it to vegetable sugars, which we can then digest as a vegetable using veg. enzymes (without sprouting we use pancreatic enzymes to digest starch which is a lot more burdensome on our digestive system). Sprouted grains are also significantly lower on the glycemic index. Sprouted grains are the *True* whole grain, the nutrients bioavailable for absorption. A longer fermentation time also allows the wild yeasts/beneficial bacteria in the sourdough loaf to continue "pre digesting" gluten, etc for us, the end result being a world of a difference in the digestive system- and the reason why

many gluten sensitive and celiac diagnosed people can happily eat sprouted fermented sourdough with no issues! Sprouting also breaks down the tannins, a bitter compound in unsprouted grain. This results in rich, creamy flour that almost smells like panna cotta or sweet porridge, a heavenly aroma when the flour is being milled ❤️ #sprout

At Cellfend, we offer a high-quality fermented wheat germ extract supplement that is made using a proprietary fermentation process to ensure maximum bioavailability and potency. Our FWGE supplement is non-GMO, gluten-free, and vegan-friendly, making it a great choice for anyone looking to support their overall health and wellness. To learn more, visit our website. cellfend.com/pages/fwge

BioCBD+™ Muscle and Joint Support, the first all natural and water soluble muscle & joint formula with our patented 100% bioavailable CBD* + Ayurvedic herbs, BioCBD™.

Through the use of patented Hybrid-NanoEngineering™, our CBD* + Ayurvedic herbs have been transformed into BioCBD™, transforming the phytonutrients into particles on the nano level. Nano particles (1/100 the width of a human hair) are easier for your body to absorb and transport to where they are needed within your body. We have set out to prove that BioCBD™ is over 10x more bioavailable in the body than any oil based CBD currently on the market. Our initial tests show that 10 mg of BioCBD™ is the equivalent of taking at least 100 mg of oil based CBD.

BioCBD™ is derived from organically grown hemp plants, and it contains all of the synergistic cannabinoids, terpenoids, and other compounds of the original plant. Each bottle contains 30 capsules.

Oil is extracted using our patent-pending ultrasonic technology at low temperature, which produces a richer, more bioavailable, and 10 times more potent omega-3 oil compared to other green-lipped mussel oils. While this alone gives us a significantly superior product, we did not stop there… to ensure that we have the undisputed, most potent, anti-inflammatory green-lipped mussel oil on the market, we added our patent-pending proprietary blend of New Zealand-grown antioxidants, that when combined with green-lipped mussel oil, have a powerful effect on balancing the inflammatory response.

We tested our TURNER Green-Lipped Mussel Oil with UAF1000+ against other green-lipped mussel oils*, and the results validated that TURNER Green-Lipped Mussel Oil is 53 times more powerful at balancing the inflammatory response.

What product would you prefer to use to help manage your joint comfort? A standard green-lipped mussel oil or our TURNER Green-Lipped Mussel Oil with UAF1000+ that is 53 times more powerful at balancing the inflammatory response?

*3rd party testing by the research laboratory; Trinity Bioactives Ltd, NZ, 2021

Polysorbate 80 and polysorbate 60 are two commonly used surfactants that find extensive application in various industries, including pharmaceuticals, food, and cosmetics. While both are part of the polysorbate family, they do have some key differences in their properties and applications. Let’s explore the dissimilarities between polysorbate 80 and polysorbate 60.

Polysorbate 80, also known as Tween 80, is a nonionic surfactant derived from polyoxyethylene sorbitan and oleic acid. It is a yellowish liquid that is soluble in water and commonly used as an emulsifier, solubilizer, and stabilizer in various formulations. Polysorbate 80 has a hydrophilic head (polyoxyethylene sorbitan) and a lipophilic tail (oleic acid), which gives it excellent emulsifying properties. It is widely used in pharmaceuticals to enhance drug solubility and bioavailability, particularly in oral and injectable formulations. Additionally, polysorbate 80 is found in cosmetics, skincare products, and food applications, where it aids in improving texture, stability, and dispersibility.

On the other hand, polysorbate 60, or Tween 60, is also a nonionic surfactant derived from polyoxyethylene sorbitan and stearic acid. It is a waxy solid at room temperature and requires heating for proper dispersion. Polysorbate 60 is primarily utilized as an emulsifier, stabilizer, and thickener in food and cosmetic formulations. It is commonly found in baked goods, ice cream, dressings, and lotions. Polysorbate 60’s emulsifying properties allow it to create stable oil-in-water emulsions and contribute to the texture and consistency of various products.

One of the main differences between polysorbate 80 and polysorbate 60 lies in their hydrophilic-lipophilic balance (HLB) values. The HLB value indicates the balance between water-soluble (hydrophilic) and oil-soluble (lipophilic) properties of a surfactant. Polysorbate 80 has a higher HLB value (around 15) compared to polysorbate 60 (HLB around 14). This means that polysorbate 80 is more hydrophilic, making it suitable for applications where a higher degree of water solubility is required. Polysorbate 60, being slightly less hydrophilic, is often preferred for formulations that require a balance between water and oil solubility.

Furthermore, the choice between polysorbate 80 and polysorbate 60 depends on the specific requirements of the application. Polysorbate 80 is frequently used in pharmaceuticals, especially for solubilizing lipophilic drugs, while polysorbate 60 is more commonly found in food and cosmetic formulations, contributing to emulsion stability and texture enhancement.

In conclusion, polysorbate 80 and polysorbate 60 are both valuable surfactants with distinct properties and applications. Polysorbate 80 is known for its higher hydrophilicity and finds application in pharmaceuticals, while polysorbate 60 is often utilized in food and cosmetic formulations that require a balance between water and oil solubility. Understanding these differences allows formulators to select the appropriate surfactant for their specific needs, ensuring optimal performance and desired outcomes in their products.

For more info visir website

medium.com/@matangiindustries/polysorbate-80-vs-polysorba...

Sprouted Sourdough Chocolate Banana Bread, decadent deep chocolate flavour. Nourishing, protein filled, sweet sprouted chickpea flour. Only one bowl necessary. 5 minutes of hands on prep time, 50 minutes in the oven. Melt 1/2 cup unsalted butter (or coconut oil) in small saucepan. While butter is melting, whisk 3 happy pastured eggs (@booneandcricketfarm are the best eggs from the happiest chickens in town!!) in a mixing bowl with some vanilla until fluffy and light, add 3 very ripe bananas- smush soft bananas with a fork and mix well into eggs. Remove butter from heat and let cool a little. Add 1 cup sourdough starter (or kefir/buttermilk if that’s what you have), melted butter, ½ cup good quality cacao, a teaspoon of non aluminum baking soda, sweetener of choice into bowl of eggs and mix everything. (We typically use 2 heaping spoons of local honey to sweeten). Incorporate 1 cup sprouted chickpea flour (we love @secondspringfoods nourishing and bioavailable chickpea flour, sweet tasting and protein loaded!) and 1 cup flour of choice (with gluten). Mix until flour disappears. If it seems too dry add another heaping tablespoon or two of sour cream or yogurt. Slide into 400F oven for 50 minutes. Bonus: scatter dark chocolate chips all over the top before baking and enjoy with afternoon coffee❤️#fika #sourdough #fermentation #bananabread #dessert #coffeebreak #chickpeaflour #sprouted #sproutedflour #chocolate #bioavailable #healthytreats #nourishing #feedingkids #sourdoughstarter #bananas #pasturedeggs #protein #afternooncoffee #cacao #antioxidants #sweettreats #eatrealfood #chickpeas #sprouting #enzymes #bakedwithlove #nutrition #bakedgoods #wholesome

Sourdough Focaccia, classic Rosemary (before and after photos) 100% sourdough leavened. Just read an interesting tidbit this morning (link on my stories) about the use of commercial yeast and how it is made with industrial waste- petrochemical byproducts, and fed with ammonia and fossil fuel sourced hydrogen, the conclusion being that each loaf made with commercial yeast contributes to green house gas emissions while feeding people toxic industrial waste.. yum!.. some food for thought from the environmental perspective, in addition to what we already know- that using commercial yeast can damage our digestive systems and makes baked goods significantly more difficult and sometimes painful to digest. Often times commercially purchased “sourdough” bread, (yes, even in small bakeries- I encourage you to ask- and almost always in large supermarkets) is leavened with the addition of commercial yeast as true sourdough requires much more time and care, something that isn’t practical in large scale production. They often add a sourdough “flavouring” to be able to label it as sourdough bread. This kind of bread has none of the health benefits of true sourdough nor are the nutrients bioavailable for absorption. Read labels carefully. Ask uncomfortable questions ❤️ #sourdough #industrialwaste #fermentation #sourdoughbread #wholefoods #nourishingtraditions #realbread #slowfood #fossilfuels #nourishingfoods #nutrition #naturallyleavened #eatrealfood #fermentedfoods #dutchoven #sproutedbread #sproutedflour #toxins #gluten #guthealth #digestion #enzymes #brot #flourwatersalt #lactobacillus #bacterialcultures #ferment #yeast #greenhousegases #environment

IV Wellness - Consider providing your body with the vitamins, minerals, and amino acids it needs to maintain maximum health in addition to water. Bypassing the digestive system, our vita-IV therapies deliver bioidentical vitamins and nutrients right to the bloodstream. This administration method offers 100% bioavailability for immediate advantages and alleviation. Although Mobile IV Therapy West Palm Beach is often ignored by doctors as a preventive measure, it is useful in treating a wide range of illnesses.

BioCBD+™ Muscle and Joint Support, the first all natural and water soluble muscle & joint formula with our patented 100% bioavailable CBD* + Ayurvedic herbs, BioCBD™.

Through the use of patented Hybrid-NanoEngineering™, our CBD* + Ayurvedic herbs have been transformed into BioCBD™, transforming the phytonutrients into particles on the nano level. Nano particles (1/100 the width of a human hair) are easier for your body to absorb and transport to where they are needed within your body. We have set out to prove that BioCBD™ is over 10x more bioavailable in the body than any oil based CBD currently on the market. Our initial tests show that 10 mg of BioCBD™ is the equivalent of taking at least 100 mg of oil based CBD.

BioCBD™ is derived from organically grown hemp plants, and it contains all of the synergistic cannabinoids, terpenoids, and other compounds of the original plant. Each bottle contains 30 capsules.

Pure Life offers liposomal multivitamin supplement with exceptional bioavailability. It contains several vitamins like D3, K2, A, AND E in pineapple flavor. Buy now on www.purelifevitamins.co.uk/

CurQfen® - Beyond Bioavailability

100% natural | Safe & Clean | Excipients free | Patented & Self GRAS affirmed | Clinically validated | Bioavailable curcumin

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Curcumin, the active compound found in Turmeric, has remarkable antioxidant properties but very poor bioavailability. This means the body had a hard time absorbing its power properly. That is why we created TurmiZn-OS™, a breakthrough, patent pending, super complex made by the chelation of Curcumin and Tetrahydrocurcumin with Zinc, which makes Curcumin more soluble, more stable and more bioavailable. This core ingredient helps the body make the most of the numerous beneficial properties of Curcumin, along with Zinc which supports a healthy metabolism. Together, all the natural ingredients in Immunity, fueled by TurmiZn-OS™, helps normalize oxidative stress and support the immune system.

Shop now and avail 10% discount. Use code IMMUNITY10. Available only at 24hrsupplement.com/

The first all natural, 100% bioavailable product for total body wellness, made with water soluble CBD* + Ayurvedic herbs. BioCBD+™ Total Body Care is not only the most bioavailable CBD* health support product, but also the safest because of our patented technology, BioCBD™.

Through the use of patented Hybrid-NanoEngineering™, our CBD* + Ayurvedic herbs have been transformed into BioCBD™, transforming the phytonutrients into particles on the nano level. Nano particles (1/100 the width of a human hair) are easier for your body to absorb and transport to where they are needed within your body. We have set out to prove that BioCBD™ is over 10x more bioavailable in the body than any oil based CBD currently on the market. Our initial tests show that 10 mg of BioCBDTM is the equivalent of taking at least 100 mg of oil based CBD.

BioCBD™ is derived from organically grown hemp plants, and it contains all of the synergistic cannabinoids, terpenoids, and other compounds of the original plant. Each bottle contains 30 capsules.

www.myvitamindeals.eu/

Beneficial Phospholipids

The plentiful phospholipids in krill oil support healthy joints and are used in every cell membrane in the body. Krill oil is different to other omega-3 supplements because 30-60% of the omega-3s are attached to these beneficial phospholipids. In fish oil, for example, the omega-3s are primarily attached to plain-old triglycerides (oils).3

A Better Source of Omega-3

Krill is considered to be free from heavy metals, very stable, and more efficiently absorbed than fish oil. Research suggests that because of the phospholipids (see above), the omega-3 in krill oil can be more bioavailable (absorbable) than that of fish oil. The sustainability of the krill harvesting operation under CCAMR, certified by Friend of the Sea, also makes Krill Oil Plus a better option for supplementing your health.3

Astaxanthin

Krill oil contains the powerful antioxidant astaxanthin, which supports a healthy immune system, skin and general health. Astaxanthin gives Krill Oil Plus its deep red color, and it has recently attracted considerable scientific interest in the areas of skin, aging and oxidative stress.

www.myvitamindeals.eu/

Pharmapex® Group's equine supplements are based on EquinYar formula use fat as a source of carbon and energy, hence guaranteeing a higher content of valuable and bioavailable nutrients. View the infographic and visit the link to get more information about the products in detail.

Take your Amino Booster everyday with you. Amino Boosters use pure Norwegian YTE® which is a highly absorbable bioavailable source of the 22 most required Amino Acids by the human body. The human body is comprised of approximately 20% protein and Amino Acids are the basic building blocks of all proteins in the body.

Primobolan, also known as Methenolone, is a popular anabolic steroid that has gained recognition in the realm of performance enhancement. With its diverse applications in medical and sports settings, understanding the composition of Primobolan is crucial. In this article, we will explore the various components that make up Primobolan and shed light on its potential effects and benefits.

Chemical Structure:

At its core, Primobolan is a synthetic derivative of dihydrotestosterone (DHT), a naturally occurring hormone in the human body. It possesses an added double bond at carbon positions one and two, which significantly enhances its anabolic properties. The chemical structure of Primobolan is meticulously designed to promote muscle growth and strength without causing excessive androgenic effects.

Active Ingredient: Methenolone:

The primary active ingredient in Primobolan is methenolone, a modified form of DHT. This modification allows for increased oral bioavailability, making it suitable for oral administration. Methenolone is classified as an anabolic steroid due to its ability to stimulate protein synthesis within muscle cells, leading to enhanced muscle growth and tissue repair.

READ MORE HERE: universitypain.net/primo-depot-benefits/

Esters:

Primobolan is available in two different ester forms: Methenolone Acetate and Methenolone Enanthate. These esters play a vital role in determining the drug's absorption rate and duration of action in the body. Methenolone Acetate has a shorter half-life and requires more frequent dosing, while Methenolone Enanthate has a longer half-life and can be administered less frequently.

Excipients and Inactive Ingredients:

In addition to the active ingredient, Primobolan may contain various excipients and inactive ingredients. These components are primarily responsible for the stability, solubility, and bioavailability of the drug. Excipients commonly found in Primobolan formulations include binding agents, fillers, and lubricants. These ingredients ensure the proper formulation and effective delivery of the active compound.

Effects and Benefits:

Primobolan is valued for its ability to promote lean muscle mass, increase strength, and improve athletic performance. Unlike other anabolic steroids, Primobolan exhibits relatively low androgenic properties, which makes it less likely to cause undesirable side effects such as acne, hair loss, or virilization in women. It is often favored by athletes seeking moderate gains without excessive water retention.

Medical Applications:

Beyond its use in performance enhancement, Primobolan has been utilized in the medical field for various therapeutic purposes. It has been prescribed to treat muscle wasting conditions, promote weight gain in debilitated patients, aid recovery following surgery or severe injuries, and counteract the catabolic effects of certain chronic diseases. However, it's important to note that the use of Primobolan should always be under medical supervision.

Conclusion:

Primobolan, with its composition centered around the active ingredient methenolone, offers an intriguing option for individuals seeking anabolic effects with minimized androgenic side effects. Understanding the composition and properties of Primobolan is essential for users and healthcare professionals alike. However, it is crucial to emphasize responsible usage, adhering to prescribed guidelines and medical supervision to ensure safety and optimal results.

#HEALTH #FITNESS #BODYBUILDING #MEN #WOMEN

www.yihonglabs.com

Anadrol or Anapolon or Oxymetholone are without a doubt the most powerful and effective oral steroid in the market. It possesses a highly androgenic effect accompanied by an extremely high anabolic effect. The gain in strength and muscle mass are 3 times greater than what you can achieve with dianabol in a shorter time frame. Anadrol is a steroid that does not cause any type of esterification and it is classified as fast acting with a short half life of approximately 4 hours. Due to this it is required to take several doses a day, no longer than every 8 hours. This is to avoid having the hormone levels decrease in the bloodstream which would decrease its anabolic effect. It is important to take oral steroids with an empty stomach, oral steroids are liposoluble substances if they are not taken properly it could notably affect the bioavailability of its active component.

There are a few new Bread List subscribers so I wanted to share the process of my sourdough to answer some of your questions (Namely, “Why can I eat this bread without any problems? I haven’t been able to eat bread in years! What’s different?”)😍 To start, our digestive systems are not meant to process gluten that has not been fermented. Sprouting activates the enzymes in the grain, bringing it to life and making the nutrients available for us to absorb. I begin with locally sourced, BC grown organic/non modified grain (regionally grown grains like Einkorn, Emmer, Spelt, Rye, Khorasan, etc). I soak them, and sprout them, activating the enzymes and making the nutrients bioavailable, a process that takes several days to just under a week depending on the grain. The sprouted grains are then gently dried at a low temperature to avoid damaging the enzymes. Once dry, the sprouted grain is milled into (100% extraction) fresh flour, so you are getting all three components of the complete grain, nothing is removed/added. Every loaf is made by hand, using sprouted flour that has been milled the same day, and then each loaf is long fermented (48h and up to a week for my celiac/gluten sensitive members), making it a loaf that is incredibly easy on the digestive system, has a low gluten content (lower than commercially available “gluten free certified” products- specific studies indicate), is low on the Glycemic Index, and most importantly, the nourishing vitamins/minerals are bioavailable for absorption. This is a quick overview, you can find more detailed earlier posts here on each specific component of the process and the importance of it, or feel free to ask! It takes time, and patience. It also brings me tremendous joy to share bread with you all ❤️ Thank you for all your kind words, and sweet photos #sourdough #fermentation #sourdoughbread #wholefoods #nourishingtraditions #realbread #slowfood #feedingmyfamily #nourishingfoods #nutrition #naturallyleavened #eatrealfood #fermentedfoods #sproutedbread #sproutedflour #gluten #guthealth #digestion #enzymes #brot #flourwatersalt #lactobacillus #bacterialcultures #ferment #sprouting #glycemicindex #bioavailability

BEST-PRO is a unique combination of highly bioavailable protein with probiotics which helps to optimize protein requirement of birds, improve gut health, growth performance and production parameters. BPPS FORTETM

Learn more - abtlenzymes.com/poultry-feed-nutraceuticals/

Enhances the bioavailability of the EGCG (Epigallocatechin Gallate) in green tea.

Taken and sent from my iPhone.

Best Haarlem Oil for horses is known for one of the best effective products and best food supplements for horses provided the exceptional bioavailability of sulfur contained in Haarlem Oil that French laboratories have engaged. One of the most important parts of the horses is the hoof quality, having a poor hoof quality beyond poor hoof care can be an indication of poor protein, vitamins, or mineral status. Haarlem Oil for horses has that nutrients (Sulphur) known to be important to respiratory wellness, it’s absolutely crucial to the animal’s health that its diet should include all of the essential nutrients, minerals and vitamins for the horses that are necessary to promote optimum hoof health.

www.horses-haarlem-oil.com/no1-food-supplement-for-horses...

Olivier Humphry analyses how earthworms affect chromium speciation and bioavailability

Vitamin D3 and K2 are essential nutrients for maintaining optimal health. This guide explores their benefits in depth.Scientific research shows that Vitamin D3 enhances calcium absorption, which is crucial for bone density. Combined with Vitamin K2, it ensures proper calcium distribution, reducing the risk of cardiovascular diseases. Coconut oil as a carrier improves bioavailability, making this supplement highly effective.The advanced microencapsulation technology used in these softgels reduces oxidation and maintains stability over time. Each softgel contains 10,000 IU of Vitamin D3 and 200 mcg of Vitamin K2, providing high potency for maximum effectiveness.For best results, take one softgel daily with a meal or as directed by your healthcare provider. Consistency is key; regular intake promotes long-term health benefits.User feedback highlights improved joint flexibility, stronger bones, and enhanced immune support. For example, John Doe reported reduced joint pain after six months of use.- Pregnant women should consult their doctor before using this supplement.

- Elderly individuals benefit greatly from its bone-strengthening properties.

oakoaks.com/blog/2025/06/19/vitamin-d3-k2-softgels-compre...

The long awaited harvest season has finally arrived, and with it some beautiful regionally grown heritage wheat varieties that we have eagerly been awaiting the last few months. These golden, buttery Khorasan grains have been slowly sprouting over the last few days and are gently drying to be milled into fresh flour tomorrow morning. All my grains are sprouted first, to wake up the sleeping enzymes, reduce phytic acid and make the nourishment they carry within bioavailable for easy absorption by our digestive systems. The incredible chemical changes that occur during the long fermentation process allow our bodies to digest this type of living flour very differently than conventional flour (using enzymes like those used for digesting vegetables as opposed to starches) and lowering the gluten levels significantly in the end result, all of which makes sprouted sourdough that has been long fermented not only full of minerals and other nutrients that we can easily absorb, but allows us to nourish our microbiome and enables the ease of digesting sprouted sourdough bread that has been properly prepared.

#sourdough #fermentation #sourdoughbread #wholefoods #nourishingtraditions #realbread #slowfood #feedingmyfamily #nourishingfoods #nutrition #naturallyleavened #eatrealfood #fermentedfoods #dutchoven #spelt #sproutedbread #sproutedflour #carbs #gluten #guthealth #digestion #enzymes #brot #flourwatersalt #lactobacillus #bacterialcultures #ferment #khorasan #sourdoughclub

#Sprouts are rich in #enzymes, bioavailable #vitamins & #phytochemicals! Enjoy them on #salads & #sandwiches! Yummy!

Nettle leaf is a fairly good source of iron. We make a fermented nettle leaf beverage to improve the iron bioavailability even more, as fermentation helps reduce the phytic acid, oxalic acid, tannic acid, and other iron inhibitors. In combination with other iron rich foods, this can be a great strategy for building your iron status.

SNEC30 Most Bioavailable Form of Curcumin and tremendous

potential for the treatment or prevention of cancer and various other diseases.

#snec30 #curcumin #turmeric

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This morning while carefully sifting through the sprouted Khorasan kernels during their final rinse, I came across several intact spikes of wheat. This made me inordinately happy, as it usually does when I’m able to get as close as possible to the raw source of whatever I’m working with- and I’ll tell you why. In the mid 1800s, some fool accidentally separated the three components of the wheat kernel, and discovered that by milling only the endosperm, and removing everything else, he could produce white flour. This fancy pants pure white flour became highly desirable amongst the wealthy (whole grain flour was for the peasants) and soon millers stopped producing whole grain and focused on meeting the demand for the more lucrative white flour. It wasn’t long until people began suffering from digestive/health problems, and knowing that the nutritional components of wheat contained in the rest of the kernel were missing and the wheat was much more difficult to digest, millers were asked to resume whole grain milling. Another solution was quickly found- “enriching” the white flour with 1 mineral- iron- and 3 vitamins. The problem? The wheat germ (the little part that contains life- the part we sprout) contains over 30 nutrients- vitamins, minerals, proteins, antioxidants, fibre, etc. It also contains healthy fats and for this reason, it is still removed from flour today, as with oxidation it quickly turns rancid soon after milling (it begins deteriorating within 30 minutes of milling- and by day 3 has lost almost 70% of its nutrients.. the flour on store shelves today is essentially dead, making it “shelf stable” (as shelf stable and nutritious as dust if you ask me😖). So here you can see the whole spike...the life giving germ pushing its way out, full of life, sprouting.. loaded with living enzymes and bioavailable, easily absorbed nutrients ☺️ @truegrainbread Thank you for these gorgeous whole kernels ❤️ #wholefoods #flour #wholegrains #sourdough #enzymes #khorasan #sprouting #sproutedgrains #whiteflour #millyourownflour #nourishingtraditions #nutrition #nourish #earth #wheat #bioavailability #bioavailable #eatrealfood #minerals #antioxidants #guthealth #digestion

Price:$32.77, SKU:NF26863, Brand:NOW Foods, Size:60 softgels

Dec

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The Transformative Power of Ketamine Therapy

Exploring the Science, Benefits, and Applications of a Revolutionary Mental Health Treatment

lyfeunit.com/

Dr. Sarah Johnson

Dr. Sarah Johnson | Board-Certified Psychiatrist

Updated: October 15, 2023 | 18 min read

In the rapidly evolving landscape of mental health treatment, ketamine therapy has emerged as one of the most promising breakthroughs in decades. Originally developed as an anesthetic in the 1960s, ketamine has undergone a remarkable transformation from an operating room staple to a revolutionary mental health intervention.

Clinical Insight: Ketamine therapy represents a paradigm shift in psychiatric care, offering rapid relief for conditions that have resisted conventional treatments. Unlike traditional antidepressants that require weeks to take effect, ketamine can alleviate symptoms of severe depression within hours.

Understanding Ketamine: From Anesthetic to Antidepressant

Ketamine was first synthesized in 1962 by Calvin Stevens at Parke-Davis Laboratories as a safer alternative to phencyclidine (PCP). Approved by the FDA in 1970 as an anesthetic, it gained widespread use during the Vietnam War due to its safety profile and minimal impact on respiratory function. For decades, ketamine remained primarily in the domain of anesthesiology and emergency medicine.

The psychiatric potential of ketamine began to surface in the early 2000s when researchers at Yale University conducted groundbreaking studies demonstrating its rapid antidepressant effects. Dr. John Krystal’s team discovered that sub-anesthetic doses of ketamine could dramatically reduce depressive symptoms in treatment-resistant patients within hours rather than weeks. This discovery ignited a revolution in psychiatric research and clinical practice.

How Ketamine Works: The Neuroscience Behind the Breakthrough

Traditional antidepressants primarily target the monoamine system (serotonin, norepinephrine, and dopamine), but ketamine works through a completely different mechanism. As an NMDA receptor antagonist, ketamine modulates glutamate – the brain’s primary excitatory neurotransmitter. This action triggers a cascade of neurobiological effects:

Synaptic Plasticity

Ketamine stimulates the formation of new neural connections and enhances synaptic plasticity, essentially “rewiring” the brain’s depressed circuitry. This neuroplasticity effect is why many patients experience profound shifts in perspective.

BDNF Release

It rapidly increases brain-derived neurotrophic factor (BDNF), a protein crucial for neuron growth, survival, and function. Low BDNF levels are associated with depression and cognitive decline.

mTOR Pathway Activation

Ketamine activates the mTOR pathway, which regulates protein synthesis necessary for forming new synaptic connections. This process helps rebuild neural networks damaged by chronic stress.

Inflammation Reduction

It reduces neuroinflammation, which is increasingly recognized as a factor in treatment-resistant depression. Ketamine lowers inflammatory cytokines that can disrupt normal brain function.

This unique mechanism explains why ketamine therapy can help patients who haven’t responded to conventional antidepressants. Rather than simply adjusting neurotransmitter levels, ketamine facilitates structural and functional changes in brain networks involved in mood regulation.

Conditions Treated with Ketamine Therapy

While depression remains the most researched application, ketamine therapy shows promise for a range of challenging conditions:

ConditionEvidence LevelResponse RateNotes

Treatment-Resistant DepressionStrong60-70%FDA-approved esketamine (Spravato) for TRD

Suicidal IdeationStrong75%+Rapid reduction of suicidal thoughts within hours

PTSD (Post-Traumatic Stress Disorder)Moderate-Strong50-60%Particularly effective for treatment-resistant cases

Anxiety DisordersModerate45-55%Including generalized anxiety and social anxiety

Chronic Pain SyndromesModerate40-60%CRPS, fibromyalgia, neuropathic pain

OCD (Obsessive-Compulsive Disorder)Emerging35-45%Promising early results

Bipolar DepressionEmerging40-50%Without triggering mania in most cases

Key Benefits of Ketamine Therapy

Rapid Symptom Relief

The most significant advantage of ketamine therapy is its speed of action. Traditional antidepressants typically require 4-6 weeks to take effect, and many patients try multiple medications before finding one that works. Ketamine often produces noticeable improvements within hours or days, providing critical relief for those in acute distress, especially individuals experiencing suicidal ideation.

Effectiveness in Treatment-Resistant Cases

Approximately 30% of depression patients don’t respond adequately to conventional treatments. Ketamine therapy offers hope to these individuals when other options have failed. Clinical trials consistently show response rates of 60-70% in treatment-resistant depression, with about 40% achieving full remission of symptoms.

Ketamine Therapy Effectiveness

70%

Response Rate for Treatment-Resistant Depression

4-24

Hours to Initial Response

40%

Achieve Full Remission

Neuroplasticity Enhancement

Ketamine uniquely promotes neuroplasticity – the brain’s ability to reorganize and form new neural connections. This biological effect creates a “therapeutic window” where patients become more receptive to psychotherapy and behavioral changes. Many clinics combine ketamine therapy with psychotherapy to maximize long-term benefits.

Reduction in Suicidal Ideation

Perhaps the most life-saving benefit of ketamine therapy is its rapid reduction of suicidal thoughts. Multiple studies show ketamine can decrease suicidal ideation within hours, making it an invaluable tool for emergency psychiatric intervention. This rapid action provides crucial time for comprehensive treatment planning.

Anti-Inflammatory Effects

Emerging research suggests that inflammation plays a significant role in treatment-resistant depression. Ketamine has demonstrated anti-inflammatory properties, particularly in reducing inflammatory cytokines in the brain. This mechanism may explain its effectiveness where conventional anti-inflammatories have failed.

Forms of Ketamine Therapy

Ketamine can be administered in several ways, each with specific advantages:

Intravenous (IV) Ketamine

The most researched and precise method, IV infusion allows for careful dose titration and immediate discontinuation if needed. Treatment typically involves 40-minute infusions in a clinical setting, with a series of 6-8 sessions over 2-4 weeks followed by maintenance treatments.

Intramuscular (IM) Injection

Similar to IV in bioavailability, IM injections offer a slightly less invasive option. Effects begin within minutes and peak around 15-20 minutes post-injection.

Esketamine (Spravato) Nasal Spray

In 2019, the FDA approved esketamine (the S-enantiomer of ketamine) for treatment-resistant depression. Administered as a nasal spray under medical supervision, Spravato offers a more accessible option with similar efficacy to IV ketamine for many patients.

Sublingual and Oral Ketamine

While less common in clinical settings, sublingual (under the tongue) and oral forms are sometimes used for maintenance between infusions. These routes have lower bioavailability and more variable absorption.

Understanding the Treatment Experience

The Transformative Power of Ketamine Therapy | Mental Health Breakthrough

The Transformative Power of Ketamine Therapy | Mental Health Breakthrough

A typical ketamine therapy session involves careful preparation and monitoring:

“The dissociative experience during ketamine therapy can be profoundly therapeutic when properly guided. Many patients report gaining new perspectives on long-standing psychological patterns.” – Dr. Michael Cooper, Ketamine Research Specialist

Preparation: Patients undergo comprehensive screening to ensure safety. They’re advised to fast for 4-6 hours before IV or IM treatments and arrange transportation home.

Setting: Treatment occurs in a comfortable, quiet room with monitoring equipment. Eye masks and headphones with calming music are often provided to enhance the experience.

The Experience: At therapeutic doses, patients typically experience mild dissociation – a sense of detachment from ordinary reality. This altered state often facilitates emotional processing and insight. Sessions last 40-60 minutes for IV therapy.

Integration: Post-session, patients spend time recovering before discussing their experience with a clinician. Many benefit from psychotherapy integration sessions to process insights gained during treatment.

Safety Profile and Potential Risks

While ketamine therapy is generally safe when administered in clinical settings, it’s not without risks:

Short-Term Side Effects

During and immediately after treatment, patients may experience:

Dissociation or feeling detached from reality

Elevated blood pressure and heart rate

Nausea (less common with anti-nausea premedication)

Dizziness or blurred vision

Temporary confusion or disorientation

Long-Term Considerations

With medically supervised use, long-term risks appear minimal, but potential concerns include:

Bladder issues: At high recreational doses, ketamine can cause cystitis, but this is extremely rare at therapeutic doses

Tolerance: Some patients may require dose adjustments over time

Psychological dependence: Minimal when used therapeutically, but requires monitoring

Important Safety Note: Ketamine therapy should only be administered by trained medical professionals in clinical settings with appropriate monitoring equipment. Patients with uncontrolled hypertension, certain heart conditions, or history of psychosis may not be suitable candidates.

Ketamine Therapy: Frequently Asked Questions

How long do the antidepressant effects of ketamine last?

The duration varies significantly between individuals. Most patients experience relief for several days to weeks after a single infusion. A typical initial protocol involves 6 infusions over 2-3 weeks, with maintenance treatments every 2-8 weeks as needed. Combining ketamine with psychotherapy often extends the benefits. For more information, see our resources section.

Is ketamine therapy covered by insurance?

Coverage is evolving. While IV ketamine for depression remains off-label (with exceptions), FDA-approved Spravato is covered by most insurance plans for treatment-resistant depression. Some plans now cover IV ketamine for specific conditions. Always verify coverage with your provider. Our ketamine therapy service page has updated insurance information.

How does ketamine compare to traditional antidepressants?

Ketamine works faster (hours vs. weeks), has a different mechanism of action (glutamate vs. monoamine systems), and is effective for many treatment-resistant cases. However, it requires clinical administration rather than daily at-home dosing and typically has a different side effect profile. Learn more about our integrated approach to mental health treatment.

Can ketamine therapy be combined with other treatments?

Yes, ketamine is often used alongside traditional antidepressants and psychotherapy. Many experts believe the neuroplasticity effects create an ideal state for therapeutic breakthroughs when combined with psychotherapy. Always coordinate with your treatment team. Contact us to schedule a consultation about integrated treatment options.

Conclusion: The Future of Ketamine Therapy

Ketamine therapy represents a paradigm shift in mental health treatment, offering hope to millions who have found little relief from conventional approaches. With its rapid action, unique mechanism, and impressive efficacy in treatment-resistant cases, ketamine has established itself as a valuable tool in psychiatric care.

Ongoing research continues to refine protocols, identify optimal candidates, and explore new applications. Current studies are investigating ketamine for conditions ranging from eating disorders to migraines, while researchers work to develop next-generation ketamine derivatives that maintain therapeutic benefits with fewer side effects.

As the field evolves, ketamine therapy stands as a testament to the importance of innovative approaches in mental healthcare. For patients who have exhausted other options, this treatment offers not just symptom relief, but renewed hope and the possibility of meaningful recovery.

Learn About Our Ketamine Program

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Key Takeaways

Ketamine therapy provides rapid relief for treatment-resistant depression, often within hours

It works through glutamate modulation, unlike traditional antidepressants

Multiple administration options exist (IV, IM, nasal spray)

Shows exceptional promise for reducing suicidal ideation

Generally safe when administered clinically with proper screening

Most effective when combined with psychotherapy

Insurance coverage is expanding, especially for Spravato

Who Might Benefit

Patients with treatment-resistant depression

Individuals experiencing suicidal thoughts

Those with PTSD unresponsive to other treatments

Chronic pain patients (CRPS, fibromyalgia)

People needing rapid symptom relief

Patients who cannot tolerate SSRIs/SNRIs

Considerations

Not recommended for those with psychosis or schizophrenia

Requires careful cardiovascular screening

Must be administered in clinical settings

Potential for dissociation during treatment

Maintenance treatments are usually needed

Cost considerations without insurance

If you’re considering ketamine therapy, consult with a psychiatrist experienced in this treatment to determine if it’s appropriate for your specific situation. Contact us for a personalized assessment.

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Mental Health Resources

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Disclaimer: This article is for informational purposes only and does not constitute medical advice. Consult with a qualified healthcare professional before making any decisions about your mental health treatment.

© 2023 LyfeUnit Wellness Center. All rights reserved.

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