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An article by Accessibility and Inclusive Design alumnus, Joe Kipling, has been published in the latest issue of the “International Journal of Disaster Resilience in the Built Environment” (Volume 2; Issue 1). Joe, who is a senior consultant at Johnson Controls Global WorkPlace Solutions, based the article on research conducted for her MSc dissertation, with which she graduated from SURFACE in 2008. The article is entitled “Access to Emergency Rest Centres: lessons to be learnt from the 2007 floods” and is centred on three case studies in the Yorkshire and Humber region of Northern England. It explores the barriers to accessing emergency shelters experienced by people with disabilities and makes recommendations on planning for more inclusive evacuation, aimed at both local authority emergency planning teams and voluntary organisations.
www.sobe.salford.ac.uk/about-us/news/surface-graduate-pub...
and in less than 24 hours, I'll be done with classes for fall semester. Granted, I'll still have CA stuff to do so I still won't be done done... but it'll feel like it.
My HSCI final was today and went pretty well, thanks to last night's 4-5 hours of studying at the hobbit hole. After the final, I got my research paper back and was pleasantly surprised to see an A. Unfortunately, I didn't have much motivation to study complex analysis, and I also got a semi-nasty headache which didn't help anything out.
I know this picture isn't a masterpiece or intriguing... but it's my life. Sometimes there are days where the only things that are worth remembering are both sitting on your lap at 12:30am.
(and I know that that's technically Wednesday, but my take on the 365days project is that the day doesn't end at midnight; it ends when I go to sleep)
May 5, 2009;
Luna getting comfortable on my paperwork. Worked on my research paper alllll day and night, I'm so glad that's over with. Only 12 days left of highschool/school all together, with the exception of college of course. Oh how sweet that sounds.
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I fondly remember nights like these. Where were the Keebler Elves when you needed them?
I told him it builds character (hahahahaha...)
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This is my sister's. She had to write a research paper which included an annotated bibliography. She actually cited wikipedia LOL.
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i wanted this shot to be my tasskaff for the day, but you can't really see the coffee. so i opted to use the close up. instead, i offer a tour of the last four months of my life.
Authors: Yasemin Numanoğlu Çevik1, Mehmet Ali Kanat
Abstract: The venoms of the scorpions Androctonus crassicauda and Leiurus abdullahbayrami, scorpion species each of the two members of the Buthidae family, were analyzed by MALDI–TOF MS in a mass range between 1 and 50 kDa. For this, all of the scorpion venoms (n=11) were prepared to equal 2mg/mL concentration. After centrifuging the venoms at 15.000 rpm for 15 minutes at +4 ºC, the supernatants (n=11) were mixed with a matrix solution (α-CHCA) in Eppendorf tubes separately. The prepared scorpion venom-matrix (SVMx) samples vortexed. For the biomass analysis, a 1µL SVMx sample was spotted onto MALDI 96 MSP was placed in the Microflex MALDI-TOF MS. The system was operated in linear positive ion mode at a 1.000-50.000 Dalton (Da) mass range. A 60 Hz nitrogen laser was employed at 337 nm as the ion source. Interspecies differentiation was evaluated over peptide and protein molecules in this mass range. The similarities and differences between two different scorpion species were revealed with the principal component analysis study, which was conducted with spectral patterns including peptide and protein profiles. The similarity rate of the LAB-123 and the LAB460 scorpion venoms of the same species was found as 66% while the similarity rates of venoms of the ACR species to the LAB species ranged from zero to 37%. It was demonstrated that scorpion venoms belonging to two different species from the Buthidae family can be differentiated with the help of dendrogram and gel profile, CCI color matrix, 3D or 2Dscattering profile, spectral mass loading data formed by peptide and protein spectral patterns of eleven scorpion venoms. It is anticipated that this approach, which was used for the first time with the application of MALDI-TOF MS-based PCA analysis for the differentiation of scorpion venoms, will be useful in differentiating venoms with different spectral patterns.
Keywords: Androctonus crassicauda, Leiurus abdullahbayrami, Scorpion, Buthidae, MALDI-TOF MSPCA analyse
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An exciting avenue for getting ideas about how a new drug might work is looking at individuals who are naturally immune or resistant to the disease. Steve Crohn lived in San Franciso in the 1970s, and lost his lover and 70 close friends to AIDS without having become infected himself. Blood tests suggested that his blood was impervious to HIV… Research found that a receptor on Steve’s blood cells called CCR2, that usually lets HIV into the cell, refused to budge – like a closed door on infection. People with mutations in the gene also showed reduced susceptibility, and a better prognosis. Importantly, Steve and others like him show no other bad effects of the mutation, suggesting that a drug that mimicked its effects would not damage other functions.
The next step is to use this knowledge to develop a drug in the ‘discovery’ phase…
This photo shows the University of Liege in Brussels, Belgium, where some of the initial research about CCR2 was carried out.
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An exciting avenue for getting ideas about how a new drug might work is looking at individuals who are naturally immune or resistant to the disease. Steve Crohn lived in San Franciso in the 1970s, and lost his lover and 70 close friends to AIDS without having become infected himself. Blood tests suggested that his blood was impervious to HIV… Research found that a receptor on Steve’s blood cells called CCR2, that usually lets HIV into the cell, refused to budge – like a closed door on infection. People with mutations in the gene also showed reduced susceptibility, and a better prognosis. Importantly, Steve and others like him show no other bad effects of the mutation, suggesting that a drug that mimicked its effects would not damage other functions.
The next step is to use this knowledge to develop a drug in the ‘discovery’ phase…
This photo shows the Walter Reed Army Research Institute in Rockville, Maryland USA, where some of the initial research about CCR2 was carried out.
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