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Muscle In (Courtesy of Janice Huss/Light Microscopy Digital Imaging Core)
City of Hope scientists are delving into the intricacies of muscle cell metabolism to understand how those cells gain nutrients, generate energy and develop into muscle tissue. Janice Huss, Ph.D., assistant professor in the Department of Diabetes and Metabolic Diseases Research at City of Hope, and her team used three fluorescent dyes — red, green and blue — to visualize different parts of muscle cells, called myocytes, as they fuse together to form myotubes, the basic structures of muscle tissue.
The blue dye stains DNA in the oval nuclei. Red shows mitochondria, the power generators of cells, which are actively producing energy. Green marks a protein called PGC-1a, which controls genes that are important in muscle cell metabolism. The researchers’ work could lead to a better understanding of the factors contributing to muscle diseases, including heart disease, as well as diabetes and other metabolic syndromes.
Image from "Beauty in the Beast," City News, Winter 2012 edition. Read and subscribe to City News at www.cityofhope.org/citynews.
Thought this was cute. These young lads were playing on this shelter, and the muscle man pose silhouetted nicely against the setting sun!
The B-17G is what most people think of when they talk about daylight precision bombing raids of Nazi Europe during the Second World War.
"Yankee Lady" is one of the most pristine B-17G's in airworthy condition.
Ademas de echarse mucho bronceador hay que concentrarse bastante para dejar el cuerpo en estado de exhibicion
Muscle memory discovery ends 'use it or lose it' dogma - "New research shows that extra nuclei gained during exercise persist even after a muscle shrinks from disuse disease or aging -- and can be mobilized rapidly to facilitate bigger gains on retraining" bit.ly/2MAnAkG