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Insect insulin like peptide 7 (Ilp7) expressiong neurons in the insect (Drosophila) central nervous system. Acquired with a Leica SP5 confocal microscope.
No las controlamos la mayoría de veces. Cuando sentimos un escalafrio, nos estremecemos, cuando nos excitamos, adrenalina. El cuerpo obedece de forma natural a sus impulsos, por eso es tan difícil controlarlos. Claro que algunas veces tenemos impulsos que preferimos no controlar, que más tarde preferiríamos haber controlado. El cuerpo es un esclavo de sus impulsos. Pero hay algo que nos vuelve humanos y que podemos controlar. Después de la tormenta, después de la carrera, después de revivir un momento pasado, podemos relajarnos y limpiar nuestra mente. Podemos intentar olvidar el pasado para volver a ser incontrolados.
this is what it's made up of, your brain that is - now whether it's your mindstuff is another question.
Les astrocytes sont des cellules en forme d'étoile dont la fonction est de fournir les nutriments nécessaires et réguler l'environnement chimique des neurones, ainsi que de contrôler et moduler l'activité de ces derniers. Ici on peut visualiser des astrocytes en culture (en vert), dérivés de modèles murins (souris) de la maladie de Steinert, qui se caractérise notamment par une accumulation d’agrégats d’ARN toxiques (acide ribonucléique chimiquement proche de l'ADN dont il est issu, visualisé ici en rouge) dans le noyau (en bleu) de ces cellules.
©Inserm, Agence National de Recherche, AFM-Téléthon.licence CC-BY-NC 4.0 international
En savoir plus :
(), ́ , est une maladie neuromusculaire héréditaire qui touche des patients de tous âges. S’il s’agit d’une pathologie rare, elle fait tout de même partie des myopathies les plus fréquentes, touchant 5 000 à 8 000 personnes vivant en France.
L'altération des cellules neuronales et non neuronales est fréquemment impliquée dans les maladies neurologiques, comme la maladie de Steinert. Cependant, les cellules non neuronales font plus rarement l’objet de recherches.
Dans une étude, publiée en 2022 dans Nature Communications, des scientifiques de l'Inserm ont démontré pour la première fois l’implication dans la maladie de Steinert des astrocytes, des cellules cérébrales qui ont longtemps été considérées comme de simples cellules de soutien des neurones. Ce travail, mené chez des souris modèles de la pathologie, révèle des dysfonctionnements au niveau des astrocytes, dans lesquelles s’accumulent des agrégats d’ARN toxiques.Ces agrégats auraient notamment un effet délétère sur la morphologie complexe et ramifiée des astrocytes, ce qui pourrait compromettre leur capacité à soutenir et à réguler la fonction synaptique (qui permet la transmission de l'information d'un neurone à l'autre) dans le cerveau.
Breaking The Spelll | Psychological Artistry - September 2013
Hi,
On the Sleight of Mind Set day we break the spell by not only teaching you the tricks and illusions but go behind the curtain and revealing the psychology of the methods.
This is where the real power lies, by giving you the recipe for turning these tricks into effects that work for you. My goal of the day is to share with you many of the tools, techniques and ideas that have entertained and mystified people over the past 100 years.
These ideas, tools and techniques are not just restricted to being used to deliver Mind Magic, they can be applied across other areas too. They allow you to:-IN THIS WEEK'S NEWSLETTER:
Raise Your Novelty Level
It's All Smoke and Mirror Neurons
Who Still Believes in Magic?
Enter the Mind Magician
Information Alone Is Not Motivation
Psychological Artistry
What Do You Get On The Workshops?
What Do People Say About The Workshops?
Booking Your Place
Show your unique perspective
Make events unique and special
Channel your drive
Exude your sense of fun
Inspire others with your ideas
Evidence your passion and empathy
Standout and apart from the crowd
Add value to others
Create curiosity and a buzz
Plant seeds of future conversations
Take up an authoritative stance
Provide a memorable experience
Forget neutrality; we have to make an impact. Your message has no value unless it makes an impact. We have to show agility in how we think, in cognitive fitness terms, we have to show mental acuity. By making an impact and showing mental acuity you make an emotional connection you are stirring the mirror neurons in others minds.
The Sleight of Mind Set Workshops are being held around the country in Doncaster - 13th September 2013, Bath - 21st September 2013, London - 1st October 2013, Glasgow - 8th October 2013 and Birmingham - 15th October 2013. For more information, please see www.mindsways.com/SMS/
RAISE YOUR NOVELTY LEVEL
Regardless of your current situation you are aware that you have a lot more potential. A way forward that comes from the neuroscience of leadership is to introduce something novel into your mix, this is precisely what the SMS day is all about. The overall idea is that by its very nature, learning Mind Magic is novel to many people, as are the tools and techniques used in it. It is about creating a new perspective, seeing your world from a different angle and raising your level through embracing novelty.
Engaging with and using Mind Magic works on many levels for you. It is novel and entertaining, it attracts and holds people's attention. You will witness the attention that floating a borrowed note in front of people gives you. It is also about firing and stirring the mirror neurons whilst fufilling a need for:
Control
Status - Leadership
Showing Special Powers
Mystery and the unexplained
Emotional Connection with others
To see some of this in action please look at these videos at www.mindsways.com/SMS/
IT'S ALL SMOKE AND MIRROR NEURONS
Enter the magician: A saying that has long been associated with magicians is that it is all done with smoke and mirrors. Well, there is obviously a bit of truth in that, but Mind Magic is done through Mirror Neurons. In 1992 an Italian scientist called Giacomo Rizzolatti came across and articulated the concept of Mirror Neurons, the general idea being that "mirror neurons" become active in our brain by observing (or even reading) about other people's behaviours. The brain actually responds as if we were doing the observed behaviour.
To see more on this, please go to www.mindsways.com/SMS/
WHO STILL BELIEVES IN MAGIC?
You may think that you don't believe in magic in any way or form., but if we take a closer look at ourselves, we are surrounded by ritual, superstitions and the belief in invisible forces. I have sat with government officers, scientists, CEOs and whole mixture of people, and one phrase quickly shows the magical beliefs that abound: "touch wood".
At its mere mention you can see people desperately looking around for wood. How many of us have lucky charms, rituals we go through before exams, interviews, meetings etc. ? As people, we want to believe that there is something beyond, that there are invisible forces that impose order in the world.
There are many reasons that lie behind why we believe weird things. One is that we want to be in control. In fact the more uncertainty and unpredictable our situations become the more we grope for control. Mind Magic, otherwise known as mentalism, uses the idea that strange things are afoot. For more information on this or anything else in this newsletter, please see www.mindsways.com/SMS/
ENTER THE MIND MAGICIAN
We have a deep seated need for status, control and mystery. The Mind Magician (and mentalists like Derren Brown) are experts at tapping in to and meeting this need, especially as many think it may just be real. Regardless of how many rational explanations are made that it's based on psychology and trickery, our need for control and our beliefs in invisible forces rejects the rational in favour of the emotional. The mirror neurons are stirring in us and the needs for mystery are met through Mind Magic. This is why Mind Magic has held its popularity over the last 100 years.
The tools, techniques and ideas accrued are all very clever, some simpler than others but all share this rich tradition. Some of this tradition is the passing on and teaching of these ideas on days like the SMS. To see more about the rich history and tradition, please see www.mindsways.com/SMS/
INFORMATION ALONE IS NOT MOTIVATION
Your message to motivate others has to make an impact and leave an impression. Otherwise no actions will follow from it. To do this we have to think carefully about how we get our message across. In doing this "show me" is more powerful than "tell me". This is why we focus so much on the Show Not Tell (SNT) philosophy.
Visual illusions are real-world demonstrations of how our minds work. Because of their subjective nature, illusions are powerful expressions of we fail to match what we see to the real world around us. This is what the SNT kit shows.
The SNT kit is designed to give you a sense and understanding of what is going on beneath the surface, allowing you to grasp the psychology of every illusion. A strong visual illusion makes you;
See something that isn't there
Fail to see something that is, or
See something different to what is there
Remember, you can't believe what you see, but you see what you believe. It's easy to imagine that these illusions happen only on pieces of paper, on computer screens or during magic tricks; easy, but wrong. They're significant in all areas of our lives, affecting;
Our Identity (How you see yourself)
Our Aspirations (What you want to do in life)
Our Drives (Why you get out of bed in the morning)
Our Ambitions (Where you want to go)
Our Personality (Who you are)
And our very essence. Illusions, then, play a critical role in your life and in everyone else's. They determine how you act, behave and think. On the day, you also receive your own copy of the SNT kit, for more information, see www.mindsways.com/SNT/
Psychological Artistry and Mind Magic has at its core the idea of showing, not just telling. Imagine any magic trick where the magician just described what was happening. This also brings to the fore the idea of ensuring Multiple Moments of Interest (MMI's) as part of your message. These are Multiple Moments of:
Interest
Interaction
Insight
Imagine then taking this and combing it with ideas from "Thought Leadership" such as:
Focus creating clarity
Clarity showing power
Power giving you understanding
Understanding giving you certainty
Certainty leading to trust
Trust leading to actions
On the Sleight of Mind Set workshop, we use Psychological Artistry and Mind Magic as a means and a prism for looking at these ideas. Please go to www.mindsways.com/SMS/ for more.
PSYCHOLOGICAL ARTISTRY
The approach we take is what we call Psychological Artistry and involves using a blend of psychology, mind magic (or mentalism), personal development and smart thinking ideas. By tapping into people's imagination, curiosity and desire for mystery we can engage people in all different areas. By adding in psychological approaches, this is strengthened. I appreciate that by its very nature, it is not a traditional approach but that is where its power lies.
Interesting examples of how all is not as it appears are the McGurk effect, Richard Wiseman's "The Incredible Colour Changing Card Effect" and a twist on a classic Fred Astaire routine. I would love to know what you think. These illustrate both the power and the approach of Psychological Artistry. Please take a look here or go to mindsways.com/SNT/
WHAT DO YOU GET ON THE WORKSHOPS?
As well as learning the tricks, tools, techniques and ideas behind Mind Magic and Psychological Artistry from the day, you will get to take away with you:
The SMS Pack :- The materials you need to perform the tricks we go through on the day as well as a number of extras
The SNT Kit :- A pack of astounding and effective materials that can be used anytime, anywhere. For more information on this, please go to www.mindsways.com/SNT/
The Support Materials :- A 2 hour DVD that shows you through the kit, how to use it and background information. This is also available online.
The Presentation :- A copy of the presentation we use on the day for your reference
The eBook :- Written materials on the tricks, including scripts and how to use them
Follow-up Support :- Contact with the trainers for further support and advice
To learn more about the content of the workshop and any of the items above, please go to www.mindsways.com/SMS/
WHAT DO PEOPLE SAY ABOUT THE WORKSHOPS?
Over the past two years of delivering these workshops, the feedback from these has been extremely positive, with people from recent workshops saying things like:
"It really was most enjoyable and enlightening"
"The most unique training day I have ever been on"
"My target was to get 3 things to add to my training, I had 11 by lunchtime"
"Fantastic day... a great eye opener!"
"Thanks to you both for a challenging, stimulating and enjoyable day"
"I've had plenty of thoughts about how some of the approaches used might be incorporated into several areas of my work"
"A great course, with plenty to think about and over"
For more on what people say, please see www.mindsways.com/what-people-say/ and for more on the workshops themselves, please go to www.mindsways.com/SMS/
BOOKING YOUR PLACE
Overall, the workshops:
Acts as a catalyst for your future development
Are for people who are curious,
Add new skills to you
Enable you to apply the techniques and ideas from Psychological Artistry and Mind Magic
Act as a source of inspiration
Provide key insights in to the Power of Perspectives
Bridges the Creativity Gap,
Look at Innovation, creativity and creating extraordinary moments
Shows the power of Personal Touch,
Highlights the importance of Show, Not Tell
Using the materials from the SNT kit and the Sleight of Mind Set workshop, you will find a wealth of practical, real world techniques that can be applied to coaching, training, consultancy, presenting, business, personal development and therapy. To register your place on the Sleight of Mind Set Workshop, please click here to go to www.mindsways.com/SMS
Thanks
George
P.S. The Show, Not Tell kit is available separately. For more on what the SNT kit is and what it does, please see www.mindsways.com/SNT/
P.P.S. We are now offering a number of bespoke Mindstwist events for organisations and businesses. These take place in-house or during conferences, meetings or during organisational events. They range from Talks, Workshops, Performances and Shows. For more information on our new range of Mindstwist Events, please see www.mindsways.com/mindstwist-events/
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Hoy es raro
como bueno y malo
estas lineas se deben a que soy mujer, estos dias afectan mis neuronas
Hoy, ayer y antes de ayer siento mi fracaso
prefiero no pensarlo, asi no lo siento tanto, pero basta que mi cabeza me traicione y en 5 segundos estoy destruida llorando.
Me gusta llorar, pero cuando no tengo pintura en los ojos.
No me gusta limpiarme la cara despues de llorar.
Tampoco me gusta llorar en la noche, por la mañana mis ojos no se ven bien, son dos pelotas de golf.
Tengo que usar anteojos, no me gusta usarlos, veo todo negro.
Tampoco me gusta llorar cuando tengo pesadillas, el sabado desperte llorando, preocupada pensando que te habias muerto.
Me dio pena, eres pequeño y fragil, no mereces morir.
Antes dije que me gusta llorar, pero ahora creo que no. No, no , no, no me gusta!
Quiero llorar contigo, seria entretenido.
Quiero comer natur de arroz con un jugo kapo de frambuesa.
Nadie tiene de frambuesa, mejor no busco mas.
Quiero plata, es la unica forma de no sentirme tan fracasada y volver a empezar.
No volvere a empezar, solo seguire.
Quiero seguir, no volver a empezar.
Siempre imagino como sera mi vida, no quiero imaginar mas.
No quiero que sea navidad, no hay nada que celebrar.
No quiero nada. Quiero todo.
Quiero dejar de flotar no sabiendo que sigue.
Si resulta lo que quiero, seria bueno. Seria buena, Si soy buena y tras un buen par de años exitosa, la gente se preguntara... en que universidad estudio esa educadora?? o solo me admiraran por lo buena que soy sin importarles cual fue mi puntaje en la puta psu? Odio la psu, me traiciono, quiero que a ti te vaya bien, al comienzo a uno igual le importa los mil puntos xq la sociedad nos hace creer que unos puntos nos hace mejores que otros, pero yo no creo eso.
Si me esfuerzo soy buena, si no, no y punto. Tampoco me quejo, tan mala no fui. "Logre" quedar en una estatal (y que?) fue lindo ver en el computador esa noticia, fue lindo ver la cara de mi mama. No fue lindo lo que seguio. No fue lindo hundirme, esos dias no fueron lindos.
Si me dieran a eligir, ubiera preferido no haber visto lo que en su momento fue lindo jamas.
Lalala, No me importa la psu, no me importa quien sale presidente, no me importas tu y no me importa la gente.
Me importa mi mundo y las personas que son contadas con una mano que son importantes para mi.
La boca hace meses me traiciono, me senti idiota, como siempre.
Asi que cuando tenga mi titulo en mano hablare, no antes.
Me importa estudiar y ser alguien en la vida. Me importa que no me falte el pan, me importa vivir normal.
No me importan los lujos, ni los autos y las casas gigantes.
Me importa mi vida y si es mejor de lo que quiero no me desagrada.
Me gusta morder el vaso de plastico que tengo en la mano.
Me gusta ver el club de la comedia, veo yingo, no me gusta que me guste ver yingo, pero si me gusta que me guste el club de la comedia.
No quiero ver television, quiero ver todas las teleseries.
No me gusta el miau de mi gato.
No me gusta que mi gato se ponga sobre el teclado me hace escribir puras to.n`´t-´-.ee´´r´as
Gene changes after nerve injury shed light on chronic pain conditions. Uninjured trigeminal neurons (left) had higher expression of genes—such as Trpv1 (green)— related to sensory detection and signaling. After injury (right), Trpv1 expression decreased, while expression of genes linked to nerve damage and regeneration—such as Atf3 (red)—increased.
Learn more: www.nidcr.nih.gov/news-events/nidcr-news/2019/new-view-ne...
Photographie prise à l’objectif à immersion à l’huile (x 1000) au niveau de la couche ganglionnaire de la valvule cérébelleuse. Le centre est occupé par le noyau et une frange cytoplasmique d’une belle cellule de Purkinje (pérycaryon rose foncé, nettement plus volumineux que celui des autres neurones). Les dendrites de ces grosses cellules traversent la couche moléculaire (rose pâle, en bas à droite) pour atteindre la surface (voir aussi P11a_016). Les petits noyaux entourant les cellules de Purkinje appartiennent probablement aux cellules gliales, et ceux, denses, en haut de l'image sont ceux des neurones (cellules granulaires et de Golgi) de la couche granulaire, dite aussi couche des grains.
- Pour plus de détails ou précisions, voir « Atlas of Fish Histology » CRC Press, ou « Histologie illustrée du poisson » (QUAE) ou s'adresser à Franck Genten (fgenten@gmail.com)
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Section at the ganglionic layer level of the valvula cerebelli (immersion x 1000). A characteristic cell of this layer is the
Purkinje cell (large, at the centre, with dark pink cytoplasm). Purkinje cells are randomly scaterred throughout the ganglionic layer and exibit large rounded or pear-shaped cell bodies (somata). Their dendrites ascend through the molecular layer (pale pink at the bottom right-hand corner - see also P11a_016) toward the external surface. The nuclei surrounding the Purkinje cells are thought to be glial (satellite) cells. The small rounded nuclei (top of the image) are those of the neurons (granular cells and Golgi cells) of the granular layer.
- For more information or details, see « Atlas of Fish Histology » CRC Press, or « Histologie illustrée du poisson » (QUAE) or contact Franck Genten (fgenten@gmail.com)