View allAll Photos Tagged Bioinformatics
Students in the biology class, Genomics and Bioinformatics, confer with professor Mathew Jones Rhoades, as they prepare their final projects in the Scripps Landstrum Laboratory at Knox College. Photo by Peter Bailley.
Figure 6A (colour inverted) from The Roles of β²-Tubulin Mutations and Isotype Expression in Acquired Drug Resistance Published in Cancer Informatics
Equipment
Nikon D90
Nikkor 50mm f/1.8
Day 11: Today started pretty good. I got informed that I got a B on my bioinformatics exam. I'm so happy! *yay*
I hope you have an awesome day too!
At the end of the GLBRC RET program, participants give presentations at a mini-symposium sharing their research experience and demonstrating one of the classroom activities they developed. Lisa shares her sequence of lessons in which students will use online bioinformatic tools to ID a new species of yeast found in Wisconsin.
Figure 3 from Functional Evolution of BRCT Domains from Binding DNA to Protein Published in Evolutionary Bioinformatics
Steven Jones, a pioneering bioinformatics expert at SFU and the B.C. Cancer Agency's Genome Sciences Centre, has been inducted into the Canadian Academy of Health Sciences.
Jones, the associate director and head of bioinformatics at the B.C. Cancer Agency's Genome Sciences Centre, also co-discovered a breakthrough in cancer causes and survival rates.
Ophiux (2016)
For her upcoming touring exhibition at Sonic Acts - against the backdrop of the emergent field of computational biology and the Google Genomics project - she invented Ophiux, a speculative pharmaceutical company, imagining its use of genetic sequencing equipment and biological machines to collect data from humans and to sample data from other organisms. Holder explains: ‘It seems as if everything has become a branch of computer science, even our own bodies probed, imaged, modelled and mapped: re-drawn as digital information’.
Ophiux was originally commissioned by Wysing Arts Centre, Cambridge, with funding from Arts Council England in 2016. The film was co-commissioned with Deptford X, London. With thanks to Dr Marco Galardini, Computational Biologist at the European Bioinformatics Institute at the Wellcome Trust Genome Campus, Cambridge, Dr Katrin Linse, Senior Biodiversity Biologist at the British Antarctic Survey, Cambridge, Alex Walker, Graphic Designer and AJA, Sound Design.
Overview of the abyss-pe makefile.
Abyss is a denovo genome assembler, that is it takes the fragmented, short read information from genome sequencing runs and assembles them into long stretches of continuous sequence, or contigs.
There may be things I have got slightly wrong in the annotation and corrections are always welcome.
Made using gvmake, from the Makefile::GraphViz perl module on CPAN.
Questi sono alcuni dei panelli dove venivano attaccati i poster (erano almeno il doppio di quelli inquadrati)
In professor Michelle Arbeitman's lab, post-doctoral fellows Matt Lebo (right, Ph.D. in Computational Biology and Bioinformatics '08) and Saori Lobbia analyze DNA gel electrophoresis data with Thomas Goldman (left), a Ph.D. candidate in molecular biology. Photo by: Philip Channing
The "quick reference" Poster available here from the Research Collaboratory for Structural Bioinformatics (RCSB)
CAREG stands for "The Center for Advanced Research in Environmental Genomics". In French, it's CRAGE, which is "Le Centre de Recherche Avancée en Génomique Environnementale".
Here's an explanation of what they do from the CAREG homepage.
"The central goal of CAREG is to study the effects of environmental stressors on genome function and expression. The members of CAREG are united by a common interest in understanding the variations that take place at the molecular, genetic, physiological and ecological levels and how these variations affect an organism's response to an environmental stressor. To determine the relationships between variations taking place at the different levels constitutes another common goal of the CAREG team. To achieve our objectives, we are applying the power of modern genomics research to problems of environmental biology – environmental genomics. We also look at the interactions between environmental heterogeneity and genetic variation in a number of microbes, plants and animals, including humans. The powerful tools of genomics, proteomics and bioinformatics research provide us with novel approaches to solve problems of environmental biology."
I guess that means that they are looking at micro-evolutionary "adaptation" on the cellular and genetic scale as changes to the environment changes local ecosystems and whatnot.
Note the greenhouse on the roof.
Taken from the window of the OC Transpo 95 Orléans bus as it passed by the Campus Transitway stop.
Database relationship graph for San Francisco Botanical Gardens specimen database showing tables and relationships.
Photo showing from left to right: Barbara Hohn (AT/CH) (a biochemist at the Friedrich Miescher Institute in Basel), Charlotte Jarvis (UK) (currently artist in residence at The Netherlands Proteomics Centre), Nick Goldman (UK) (European Bioinformatics Institute in Hinxton (UK)) and Michael Doser (AT/CH).
at "the TOTAL RECALL – Symposium – Panel 2".
credit: tom mesic
www.sk.ru/en Boston, USA 18JUN2012
Representatives from the Skolkovo Foundation participated in the 2012 BIO International Convention at the Boston Convention and Exhibition Center June 18-21. The conference, attended by pharmaceutical companies, teaching hospitals, venture capital firms and over 500 biotechnology companies, drew more than 15,000 attendees to the Boston area.
The introductory workshop in bioinformatics and genomics held at ILRI, Nairobi 24-28 February 2014, was conducted by BecA-ILRI Hub in collaboration with the National Science Foundation, the Fulbright Foundation, and Reed and Lewis & Clark Colleges. The workshop was facilitated by Prof Sarah Schaack, Assistant Professor of Biology, Reed College, USA . (photo credit: BecA-ILRI Hub/Ethel Makila)
Two CSE undergraduate students conduct summer research on the applications of computer science in the field of bioinformatics.
This is my first scientific poster. Please criticise my scientific poster. I really need some inputs. Thanks.
My main problem is actually the size limit. I take out the bioinformatic analysis, which include the theoretical modelling of the protein and the sequence alignment. :)
An overview of how the abyss-pe makefile assembles a genome. Hope this helps some other people when using the ABYSS assembler. Annotated version here: <a www.flickr.com/photos/robsyme/3815704409/
Most of the steps (from 'name-3.fa' down) are dedicated to using the paired end read data.
Made using gvmake, from Makefile::GraphViz on CPAN.
Participants in the Advanced Bioinformatics annual training workshop conducted by BecA-ILRI Hub in collaboration with the Swedish University of Agriculture Sciences (SLU) in Nairobi, Kenya October 7th - 18th, 2013
Photo credit: BecA-ILRI/Tim Hall
Bryn Williams-Jones of Connected Discovery Ltd: "SME's form a huge percentage of the end-users of bioinformatics resources. I'm here to talk about what they need the data for, and how they need the services to evolve. I'm also very interested to learn about how biotech works in Italy. There are a lot of people doing very valuable work here, but they need to talk about it more widely."
Participants in the Advanced Bioinformatics annual training workshop conducted by BecA-ILRI Hub in collaboration with the Swedish University of Agriculture Sciences (SLU) in Nairobi, Kenya October 7th - 18th, 2013
Photo credit: BecA-ILRI/Tim Hall
Test of an art concept for an institutional fundraiser. The sharp-eyed and bored among you may recognize six of my previous photos in this mess.
The original composition was about the size of the "blackboard" in the centre. When I increased the canvas size to add a gray border, parts of the other layers magically appeared. Totally unintentional.
All feedback gratefully received. I tried brightening it, and increasing the contrast and colour, but it lost something in that process. So this is the working version, for now.
Best viewed large on black.
Aim: To analyze various single subunit DNA dependent RNA polymerases and identify conserved motifs, active site regions among them and propose a plausible mechanism of action for these polymerases using the T7 RNA polymerase as a model system.
Study Design: Bioinformatics, Biochemical, Site-directed mutagenesis and X-ray crystallographic data were analyzed.
Place and Duration of Study: Department of Molecular Microbiology, School of Biotechnology, Madurai Kamaraj University, Madurai – 625 021, India, from 2010 to 2013.
Methodology: The advanced version of Clustal Omega was used for protein sequence analysis of various SSU DNA dependent RNA polymerases from viruses, mitochondria and chloroplasts. Along with the conserved motifs identified by the bioinformatics analysis and with the data obtained by X-ray crystallographic, biochemical and site-directed mutagenesis (SDM) were also used to confirm the possible amino acids involved in the active sites and catalysis of these RNA polymerases.
Results: Multiple sequence analyses of various single subunit (SSU) DNA dependent RNA polymerases from different sources showed only a few highly conserved motifs among them, except chloroplast RNA polymerases where a large number of highly conserved motifs were found. Possible catalytic regions in all these polymerases consist of a highly conserved amino acid K and a ‘gatekeeper’ YG pair. In addition to, these polymerases also use an invariant R at the -4 position from the YG pair and an invariant S/T, adjacent to the YG pair. Furthermore, two highly conserved Ds are implicated in the metal-binding site and thus might participate in the catalytic process. The YG pair appears to be specific for DNA templates as it is not reported in RNA dependent RNA polymerases.
Conclusion: The highly conserved amino acid K, the ‘gatekeeper’ YG pair and an invariant R which are reported in all DNA polymerases, are also found in these DNA dependent RNA polymerases. Therefore, these RNA polymerases might be using the same catalytic mechanism as DNA polymerases. The catalytic amino acid K could act as the proton abstractor and generate the necessary nucleophile at the 3’-OH and the YG pair, R and the S/T might involve in the template binding and selection of nucleoside triphosphates (NTPs) for polymerization reactions. The two highly conserved Ds could act as the ‘NTP charge shielder’ and orient the alpha phosphate of incoming NTPs for the reaction at the 3’-OH growing end.
Author(s) Details
Dr. Peramachi Palanivelu
Department of Molecular Microbiology, School of Biotechnology, Madurai Kamaraj University, Madurai –625 021, India (Retd.).
Read full article: bp.bookpi.org/index.php/bpi/catalog/view/54/590/477-1
View More: www.youtube.com/watch?v=n1nk0tu3U3Q
Figure 2 from Computational Design of Targeted Inhibitors of Polo-Like Kinase 1 (Plk1) Published in Bioinformatics and Biology Insights
A BecA-ILRI Hub Africa Biosciences Challenge Fund Fellow undertakes a practical exercise at a bioinformatics workshop.
Photo Credit: BecA-ILRI Hub/Tim Hall
Original full Poster available here from the Research Collaboratory for Structural Bioinformatics (RCSB)
Participants in the Advanced Bioinformatics annual training workshop conducted by BecA-ILRI Hub in collaboration with the Swedish University of Agriculture Sciences (SLU) in Nairobi, Kenya October 7th - 18th, 2013
Photo credit: BecA-ILRI/Tim Hall
Dr Laura Purdie, PhD and BecA-ILRI Hub Africa Biosciences Challenge Fund Fellows at a bioinformatics workshop.
Photo Credit: BecA-ILRI Hub/Tim Hall
The introductory workshop in bioinformatics and genomics held at ILRI, Nairobi 24-28 February 2014, was conducted by BecA-ILRI Hub in collaboration with the National Science Foundation, the Fulbright Foundation, and Reed and Lewis & Clark Colleges. The workshop was facilitated by Prof Sarah Schaack, Assistant Professor of Biology, Reed College, USA . (photo credit BecA-ILRI Hub/Ethel Makila)