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Porto
There are a number of interesting priceless historic ecclesiastical artifacts to be seen in the treasure room of Porto's Cathedral.
read more : travel-tips.s3-website-eu-west-1.amazonaws.com/porto-cath...
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Locandina:
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www.imdb.com/it/title/tt12784484/mediaviewer/rm2907022337...
www.imdb.com/it/title/tt12784484/mediaviewer/rm2940576769...
www.primevideo.com/detail/Romantic-Guide-to-Lost-Places/0...
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click to activate the small icon of slideshow: the small triangle inscribed in the small rectangle, at the top right, in the photostream (it means the monitor);
or…. Press the “L” button to zoom in the image;
clicca sulla piccola icona per attivare lo slideshow: sulla facciata principale del photostream, in alto a destra c'è un piccolo rettangolo (rappresenta il monitor) con dentro un piccolo triangolo nero;
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www.fotografidigitali.it/gallery/2726/opere-italiane-segn...
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I'm sharing here on Flickr a (long) series of photos, taken in early August this year, during a short vacation in Calabria, at a holiday village located near a beach I've been frequenting with my family for several years now, during our short summer vacations. The setting, however, is very different from the beaches I normally frequent near my home in Taormina, with very crowded beaches and a sea that is also very popular with yachtsmen of all kinds. In this part of Calabria, the beaches are rarely crowded (except on weekends, but not too much). In short, it's a sort of almost tropical paradise, with very little yachting. Adjacent to the holiday village is a kitesurfing club, very popular with enthusiasts of this wonderful sport, which thrives on the sea and the wind. I photographed an 84-year-old kitesurfer, whose mettle is steely, still giving athletes much younger than him a run for their money. A friendly and sweet horsewoman from the nearby stables arrived unexpectedly in the beach village, accompanied by her father, both astride two magnificent colts. This created a moment of joy and curiosity for both the parents and their little ones, who were likely seeing these magnificent and docile animals up close and personal for the first time. Unexpectedly, a very special party broke out on the beach. Seeing it made me feel like I was no longer in Calabria, but rather transported to the other side of the globe, to the Hindu festival called Holi, with its throwing of colored powders (in India, this festival marks the end of winter and the arrival of spring, as well as symbolizing the victory of good over evil). I know it thanks to the evocative photographs often published on various photography websites.
I'll end by briefly mentioning the photographic technique I've often used in my photographs. I've created "blur" photographs—blurry, slightly blurry, and unfocused—at the time of shooting, simply by lengthening the exposure time and then also using some panning. Finally, I'd like to thank the sweet and beautiful models who posed for me, allowing me to further enhance this (long-winded) photographic story.
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Propongo qui su Flickr, una (lunga) serie di foto, realizzate nei primi giorni di Agosto di quest’anno, durante una mia breve vacanza in Calabria, in un villaggio vacanze sito a ridosso di una spiaggia che oramai frequento insieme alla mia famiglia, durante le nostre brevi vacanze estive, da diversi anni, fotografie quindi aventi per tema la “beach photography”; purtuttavia l’ambientazione è molto diversa rispetto alle spiagge che frequento normalmente vicino casa mia a Taormina, con spiagge molto affollate, il mare anch’esso super frequentato da diportismo nautico di ogni tipo, in questa zona della Calabria le spiagge sono invece poco frequentate (tranne il fine settimana, ma neanche troppo), insomma, una specie di Paradiso quasi tropicale, con pochissime imbarcazioni. Adiacente al villaggio vacanze c’è un club di Kitesurf, molto frequentato da appassionati di questo meraviglioso sport, sport che si nutre di mare e di vento. Ho fotografato un kitesurfer di 84 anni, la cui tempra è di acciaio, che dà ancora molto filo da torcere ad atleti molto più giovani di lui. Nel villaggio a sorpresa è arrivata una simpatica e dolce cavallerizza proveniente dal vicino maneggio, con lei anche il suo papà, entrambi a cavallo di due magnifici puledri, creando un momento di allegria e curiosità, sia per i genitori, che per i loro piccoli, per i quali, molto probabilmente, era la prima volta che potevano vedere da vicino, e poterli anche toccare, questi magnifici e docili animali. A sorpresa, inaspettatamente, sulla spiaggia ha preso vita un party molto particolare, nel vederlo mi sembrava di non essere più in Calabria, ma di essere stato proiettato dall’altro lato del globo, in quella festa Indù chiamata Holi, con lancio di polveri colorate (in India questa festa segna la fine dell'inverno e l'arrivo della primavera, oltre a simboleggiare la vittoria del bene sul male), festa che conosco grazie a fotografie molto suggestive spesso pubblicate sui vari siti fotografici.
Termino accennando brevemente alla tecnica fotografica che ho spesso adottato nel realizzare le mie fotografie, ho realizzato al momento dello scatto fotografie del tipo “blur”, cioè mosse, un po’ confuse, non incise, ottenute allungando i tempi di esposizione. Infine ringrazio le dolcissime e belle modelle, che hanno voluto posare per me, consentendomi di rendere più grazioso questo mio (prolisso) racconto fotografico.
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Seoul, Korea, cold January night, year 2014
I wish I shot Ricoh GR at still higher ISO even on these brightly lit streets. Many shots (including this one) came out somewhat underexposed.
Post-processing was done in Lightroom, luminance noise reduction wasn't applied. Preset download.
Stagecoach's main route through Stockton-on-Tees is the 36/37/38 corridor from Hartlepool and various suburbs of Stockton through to Middlesbrough, for which a batch of new ADL Enviro 200MMC were acquired by Cleveland Transit last year. tiscon-maps-stagecoachbus.s3.amazonaws.com/Timetables/Nor...
26276/SN69 ZHA seen in Stockton on 05/03/20.
German Jagdpanzer 38 Hetzer Tank Destroyer
tank-photographs.s3-website-eu-west-1.amazonaws.com/bayea...
Scan from print
At one time, the Manor of St Tudy belonged to the Nicholl family.
Partly covering the south aisle east window is the marble and freestone monument, erected in 1681 by his wife Amy, to Anthony Nicholl of Penvose (1611-1659); which was moved from the choir arcade bay in 1873. www.flickr.com/gp/52219527@N00/7PMkja6r1f
Once painted, some of its original colours can still be seen- Anthony & Amy were originally surrounded by coats of arms and other ornamentation. The arms which were probably on the top are now on the floor nearby www.flickr.com/gp/52219527@N00/nJGW46PB3q
Anthony was one of 11 children born to Humphrey Nicholl (1577–1643), and Philippa 1669 www.flickr.com/gp/52219527@N00/zhAS9eVJCg daughter of Sir Anthony Rous / Rouse MP and Phillipa Pym ( His father was a member of the Cornish gentry and descended from Oto Nicoll, an immigrant from Guernsey, who sat for Lostwithiel in 1437 and acquired Penvose in 1446.
He was the grandson of Humphrey Nicholl 1597 of Penvose St Tudy & wife Jane Roscarrock www.flickr.com/gp/52219527@N00/L2pj10p04Z
He m Amey / Amy (1609–1685) daughter of Peter Speccot 1655 flic.kr/p/DVxn2u MP of Thornbury & Mary daughter of Sir John Mallet & Mary daughter of Sir John Popham, MP, Speaker of the House of Commons by Amy Adams
Amy was the grand daughter of Sir John Speccot 1641 & 1st wife Elizabeth Edgecombe flic.kr/p/DVxn1h
Children: - 5 sons www.flickr.com/gp/52219527@N00/K9UMbA1jJv & 4 daughters
1. Anthony
2. John
3. Peter
4. Humphrey
5. Anthony
"The branches here which you do see spring from the roote of this decay'd tree
The blossoms skyward were, though now blown downe
Some in the country and some in the towne
Two here repose by their father's side In St Tudy church for sometime must abide.
One onely ........
From twixt the ......
His laurells green, this speaks .......
... first and last hath tooke and .......
That the honor of his house may here decay
.... humbly souls on gentle ........ pray "
In April 1640, Nichol was elected Member of Parliament for Bossiney in the Short Parliament. He was elected MP for Bodmin for the Long Parliament in November 1640. He was closely connected with parliamentarians Pym and Hamden. (His mother Philippa Rouse was a half-sister of John Pym and a second cousin of Sir Francis Drake). - But for Pym's influence, he would never have been allowed to take his seat for he had not been legally elected. With other Presbyterians he took the "Solemn League and Covenant" to buy Scots' help in the war against King Charles I. He was an extreme presbyterian and was one of the eleven members impeached in July 1647 accused by senior Army officers of attempting to destabilise the kingdom.. However when the king was captured in that year, he refused to vote for his death and was accordingly accused by Cromwell with "high crimes and misdemeanours", impeached and imprisoned.
He obtained a speaker's pass to go to Cornwall but was arrested on 17 August and brought back to Thomas Fairfax in Kingston upon Thames. He was well treated and after 2 days' detention was sent to London with an accusation of High Treason. He escaped with the connivance of his captors. He was disabled from sitting in parliament by an order in January 1648, but this was revoked in June 1648 after which he was made Master of the Armouries of the Tower as compensation for the loss of his position as customer of Plymouth.
In 1650 he ejected the legal Rector of St Tudy, Obadiah Ghossip, and brought in his own nominee Nicholas Leverton
After his death and the restoration of the monarchy in 1660 , Leverton was ousted and an orthodox churchman appointed.
In 1654 Nicholl was elected as one of the MPs for Cornwall in the First Protectorate Parliament. He was re-elected MP for Cornwall in 1656 for the Second Protectorate Parliament. He was appointed High Sheriff of Cornwall in 1657.
He died in London in February 1658 and was buried in the graveyard attached to the Savoy chapel
His widow Amy m2 (2nd wife) John Vivian 1616 - 1696 of St Columb son of John Vivian 1647 & Mary daughter of William Cavell of Trehaverock & Jane daughter of William Pomeroy & Mary Bevill; (John m1 Mary Glanville 1669; m3 Anne 1688 daughter of Sir John Trelawny, 1st Baronet Trelawny and Elizabeth Mohun;
His son Humfrey (1651-1699) is named on a separate marble tablet at the foot of the tomb, as a Patron of Letters, Peace and Religion, and zealous in the cause of the restored Monarchy.
- Church of St Tudy, Cornwall
en.wikipedia.org/wiki/Anthony_Nicholl
s3-eu-west-1.amazonaws.com/s3.spanglefish.com/s/37629/doc...
Picture with thanks - copyright Ian www.cornishchurches.com/St%20Tudy%20Church%20Cornwall%20-...
Hind’s Feet in High Places, Olympic National Park buffer-uploads.s3.amazonaws.com/515610818bd7f8f04d000001/... - More at www.Zoomdak.com
RTA Cleveland"Red line"(クリーブランド地下鉄) // Tokyu Car Corporation 1984
Tokyu Car Corporation(東急車輛) Japan 1984
Japan Railway Magazine(鉄道ファン) 1993-03
kusumirail.s3.ap-northeast-1.amazonaws.com/rf/1993/1993_0...
**Kay County Courthouse** - National Register of Historic Places Ref # 84003070, date listed 8/23/1984
Courthouse Sq.
Newkirk, OK (Kay County)
The Kay County Courthouse (1925) is a large, approximately rectangular structure with a raised basement and an attic story. The attic story has a hipped, tiled roof. The central portion of the front facade has a monumental porticoed entranceway with Ionic columns. The main entranceway is raised and is approached by a broad flight of stairs. The monumental, central pediment has an ornamented typpanum with a raised, garlanded wreath design. The frieze is Inscribed, "KAY COUNTY COURTHOUSE." Four ornamental urns decorate the parapet above the projecting cornice. (1)
References (1) NRHP Nomination Form s3.amazonaws.com/NARAprodstorage/lz/electronic-records/rg...
RTA Cleveland"Red line"(クリーブランド地下鉄) // Tokyu Car Corporation 1984
Tokyu Car Corporation(東急車輛) Japan 1984
Japan Railway Magazine(鉄道ファン) 1984-03
kusumirail.s3.ap-northeast-1.amazonaws.com/rf/1984/1984_0...
RTA Cleveland"Red line"(クリーブランド地下鉄) // Tokyu Car Corporation 1984
Tokyu Car Corporation(東急車輛) Japan 1984
Japan Railway Magazine(鉄道ファン) 1984-03
kusumirail.s3.ap-northeast-1.amazonaws.com/rf/1984/1984_0...
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mashable.com/2016/09/01/stranger-things-dungeons-dragons-...
Here in the UK, there’s been a spate of harassment and even arrests of innocent photographers by police invoking anti-terrorism laws.
So this is an easy-to-read wallet-sized infosheet of photographer legal rights here in the UK.
Download and print a PDF version here:
s3.amazonaws.com/infobeautiful/photographersrights_UK.pdf
More info at
www.informationisbeautiful.net
==================
Designed by David McCandless and Joe Swainson.
sources:
cms.met.police.uk/news/policy_organisational_news_and_gen...
www.met.police.uk/stopandsearch/what_is.htm
**Old Richmond County Courthouse** - National Register of Historic Places Ref # 78001004, date listed 12/22/1978
432 Telfair St.
Augusta, GA (Richmond County)
The Old Government House or Courthouse (1801) has played a significant role in the social, architectural and governmental history of Augusta, serving for twenty years as the Richmond County Courthouse and thence as a private residence for several distinguished families of Georgia and South Carolina.
By 1821, this building was considered too small and a new courthouse was built on Greene Street. The county sold the old courthouse to the city which immediately sold the building and courthouse square to Samuel Hale. In 1839, Hale, having financial difficulties, sold the structure to Paul Fitzsimmons. (1)
References (1) NRHP Nomination Form s3.amazonaws.com/NARAprodstorage/lz/electronic-records/rg...
Regards,
Col
[photo]
Col Skinner
Digital Strategist & Consultant | Profoundry Ltd
Call: <
col@?profoundry.?co<
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Sent from my Mobile
On Sat, Jan 09, 2016 at 8:53 pm, Col Skinner - Profoundry <col@profoundry.co<
Regards,
Col
[photo]
Col Skinner
Digital Strategist & Consultant | Profoundry Ltd
Call: <
col@?profoundry.?co<
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Sent from my Mobile
**Greer County Courthouse** - National Register of Historic Places Ref # 85000682, date listed 3/22/1985
Courthouse Sq.
Mangum, OK (Greer County)
The Greer County Courthouse is a large red brick building with granite and limestone trim. Built in 1906, it is three stories high. It originally had an elaborate copper-covered dome centered on the top, but it was removed in the 1940's because the weight of the dome caused structural damage to the building. (1)
References (1) NRHP Nomination Form s3.amazonaws.com/NARAprodstorage/lz/electronic-records/rg...
This seems to be the Tábor town hall. Took a while until I found out! It's the wrong side I took the picture from - not knowing what I photographed...
s3.amazonaws.com/gs-waymarking-images/b4cf2a7d-2830-462f-...
(This side would have been clearer).
But well, I'm glad that I could reconstruct our trip so far! :)
SMTOWN Now Vyrl Update
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Time Line
nuk-tnl-editorial-prod-staticassets.s3.amazonaws.com/2014...
History
Thalidomide was created by Grünenthal in 1953 and was used in the late 1950s and early 1960s as a "wonder drug" to treat morning sickness, headaches, coughs, insomnia and colds. Thalidomide was marketed in the UK under the name Distaval in 1958, and advertisements emphasized the drug's complete safety, using phrases such as “non-toxic” and “no known toxicity”.
However, in 1961 an Australian doctor, William McBride, wrote to the Lancet after noticing an increase in deformed babies being born at his hospital – all to mothers who had taken Thalidomide.
Between 1958 and 1962 tens of thousands of women throughout Europe found that the baby they were carrying unaccountably miscarried, or, worse, after they gave birth were told it was stillborn. Thousands more discovered that their babies had severe birth defects, missing arms, legs, or with severe reductions to these limbs, or even worse, damage to their internal organs, brain, heart, kidneys, intestines, genitals, etc. During 1962 record keepers began to count all of the children living who were born damaged by the drug. The only complete records are of those who survived long enough to participate in the national compensation schemes, which were established in Germany, Britain, Japan, Sweden and Australia in the 1970s. The difficulty in uncovering the full toll of the disaster begins with the unknown numbers of miscarriages and stillbirths (possibly up to ten times the number of live births), and the widespread practice of infanticide.
The Thalidomide injuries did not stop once the babies were born. At the age of fifty, the Thalidomide Trust’s records show that around half of all survivors are coping with chronic pain – mainly from muscles and joints (musculo-skeletal pain), largely as a result of the challenges of living with missing or damaged limbs. For many, their bodies are deteriorating far faster than able-bodied people. Several have been told words to the effect “your body is getting the problems of someone in their seventies”, which at forty to fifty years of age is not good news. At least a quarter are coping with developing neurological problems, tingling, numbness, and pain in their affected limbs. This means that a person may be holding a cup, for instance, and the next thing they know is it has fallen to the floor and broken, because of the numbness in their hand. For these survivors, the disaster is still slowly unfolding in their day-to-day lives.
Grünenthal scientists were not only negligent in failing to withdraw the drug when reports of problems came in, or for failing to test it according to the standards of the time, but more than most companies they were very well placed to anticipate the possibility that Thalidomide would cause birth defects.
Grünenthal initially denied claims that the drug hadn’t been extensively tested according to the standards of the time, but once the scandal became undeniable, they sought to deflect blame and limit damage.
In 1961 Thalidomide was eventually withdrawn after being found to be a teratogan - a cause of birth defects. 12 years later, the UK company Distillers Biochemicals Limited (now Diageo) – which was responsible for distributing the drug in the UK – reached a compensation settlement following a legal battle by the families of those affected.
Based on incomplete medical evidence and unrealistic expectations of Thalidomide survivors future needs this settlement has turned out to be at an inadequate level. With all Thalidomide survivors in the UK now over the age of 50, it is no longer sufficient to deal with their rising cost of living, and the dramatic deterioration of their health.
To this day, Grünenthal have never accepted responsibility for the suffering caused by Thalidomide. On September 1st 2012, The Grünenthal Group released a statement containing an apology, stating that it "regrets" the consequences of the drug, which led to babies being born without limbs during the 1950s and 1960s. Although the statement was welcomed by some Thalidomide survivors, it is still not an acceptance of responsibility. They just want to live a comfortable life, and that means Grünenthal should be held accountable and pay for their mistake financially.
Spanish
Historia
La talidomida fue creado por Grünenthal en 1953 y fue utilizado a finales de 1950 y principios de 1960 como una "droga milagrosa" para el tratamiento de las náuseas, dolores de cabeza, tos, insomnio y resfriados. La talidomida fue comercializada en el Reino Unido bajo el nombre Distaval en 1958, y destacó los anuncios de seguridad completa del medicamento, utilizando frases como "no tóxico" y "no hay toxicidad conocida".
Sin embargo, en 1961 un médico australiano, William McBride, escribió a la revista The Lancet después de notar un aumento en los bebés que nacen deformes en su hospital - todo a las madres que habían tomado Talidomida.
Entre 1958 y 1962, decenas de miles de mujeres de toda Europa descubrieron que el bebé que llevaban inexplicablemente abortado, o, peor aún, después de dar a luz se les dijo que estaba muerto. Miles de personas descubrieron que sus bebés nacieron con defectos congénitos graves, los brazos, las piernas, que faltan o con reducciones severas a estos miembros, o peor aún, el daño a sus órganos internos, cerebro, corazón, riñones, intestinos, genitales, etc Durante 1962 guardianes de los registros empezó a contar toda la vida los niños que nacieron dañado por la droga. Los únicos registros completos son de los que sobrevivieron lo suficiente como para participar en los sistemas nacionales de indemnización, que se establecieron en Alemania, Gran Bretaña, Japón, Suecia y Australia en la década de 1970. La dificultad para descubrir el número de víctimas del desastre comienza con los números desconocidos de abortos involuntarios y mortinatos (posiblemente hasta diez veces el número de nacidos vivos), y la práctica generalizada del infanticidio.
Las lesiones de la talidomida no se detuvo una vez que los bebés nacieron. A la edad de cincuenta años, los registros de la confianza talidomida muestran que cerca de la mitad de todos los sobrevivientes están lidiando con el dolor crónico - principalmente de músculos y articulaciones (dolor musculoesquelético), en gran parte como resultado de los desafíos de vivir con la falta o ramas dañadas. Para muchos, sus cuerpos se deterioran mucho más rápido que las personas sanas. Algunos han dicho palabras en el sentido de "su cuerpo está recibiendo los problemas de alguien en los setenta", que a los cuarenta o cincuenta años de edad no es una buena noticia. Al menos una cuarta están lidiando con el desarrollo de problemas neurológicos, hormigueo, entumecimiento y dolor en las extremidades afectadas. Esto significa que una persona puede ser la celebración de una taza, por ejemplo, y lo siguiente que sé es que ha caído al suelo y se rompe, debido a la sensación de adormecimiento en la mano. Para estos sobrevivientes, el desastre está siendo poco a poco se desarrolla en su día a día.
Grünenthal científicos no sólo fueron negligentes al no haber retirado la droga cuando los informes de problemas de vino, o por no probarlo de acuerdo a los estándares de la época, pero más que la mayoría de las empresas que estaban muy bien situados para prever la posibilidad de que la talidomida haría causar defectos de nacimiento.
Grünenthal inicialmente negó las acusaciones de que el medicamento no ha sido ampliamente probado de acuerdo con los estándares de la época, pero una vez que el escándalo se hizo innegable, trataron de desviar la culpa y limitar el daño.
En 1961, la talidomida fue finalmente retirada después de haber sido encontrado para ser un teratogan - una de las causas de los defectos congénitos. 12 años después, el Reino Unido, Distillers Company Limited (ahora Bioquímicos Diageo) - encargada de la distribución de la droga en el Reino Unido - llegó a un acuerdo de compensación después de una batalla legal por las familias de los afectados.
Sobre la base de evidencia incompleta médica y expectativas poco realistas de la talidomida futuro sobrevivientes necesita esta solución ha resultado ser en un nivel adecuado. Con todos los sobrevivientes de la talidomida en el Reino Unido ahora más de 50 años de edad, ya no es suficiente para hacer frente a su creciente costo de vida, y el dramático deterioro de su salud.
A día de hoy, Grünenthal nunca ha aceptado la responsabilidad por el sufrimiento causado por la talidomida. El 1 de septiembre de 2012, el Grupo Grünenthal emitió una declaración que contenga una disculpa, diciendo que "lamenta" las consecuencias de la droga, lo que llevó a los bebés que nacen sin extremidades durante los años 1950 y 1960. Aunque la declaración fue bien recibida por algunos sobrevivientes de la talidomida, no es todavía una aceptación de responsabilidad. Ellos sólo quieren vivir una vida cómoda, y eso quiere decir Grünenthal deben rendir cuentas y pagar por su error financieramente.
Italian
Storia
La talidomide è stato creato da Grünenthal nel 1953 ed è stato utilizzato alla fine del 1950 e 1960 come un "farmaco miracoloso" per curare la malattia di mattina, mal di testa, tosse, insonnia e raffreddori. La talidomide è stato commercializzato nel Regno Unito con il nome di Distaval nel 1958, e la pubblicità ha sottolineato sicurezza del farmaco, con frasi come "non tossico" e "nessuna tossicità conosciuto".
Tuttavia, nel 1961 un medico australiano, William McBride, ha scritto al Lancet dopo aver notato un aumento delle nascite di bimbi malformati essendo nati a suo ospedale - tutti da madri che avevano assunto talidomide.
Tra il 1958 e il 1962 decine di migliaia di donne in tutta Europa ha scoperto che il bambino che portavano inspiegabilmente abortito, o, peggio, dopo che ha dato alla luce hanno detto che era morto. Altre migliaia hanno scoperto che i loro bambini hanno gravi difetti di nascita, braccia, gambe, mancanti o con gravi riduzioni a queste arti, o peggio ancora, danni ai loro organi interni, cervello, cuore, reni, intestino, genitali, ecc Nel 1962 custodi record cominciò a contare tutta la vita i bambini che sono nati danneggiati dal farmaco. Le uniche registrazioni complete sono di coloro che sono sopravvissuti abbastanza a lungo per partecipare ai sistemi di indennizzo nazionali, che sono stati stabiliti in Germania, Gran Bretagna, Giappone, Svezia e Australia nel 1970. La difficoltà nello scoprire il bilancio del disastro inizia con i numeri sconosciuti di aborti spontanei e nati morti (forse fino a dieci volte il numero di nati vivi), e la pratica diffusa di infanticidio.
Le lesioni Talidomide non si è fermata una volta che i bambini sono nati. All'età di 50, del Trust talidomide i tabulati mostrano che circa la metà di tutti i sopravvissuti stanno affrontando con dolore cronico - principalmente da muscoli e le articolazioni (il dolore muscoloscheletrico), soprattutto a causa delle sfide della vita con mancanti o arti danneggiati. Per molti, i loro corpi si stanno deteriorando molto più veloce di persone abili. Molti hanno detto parole per l'effetto "il tuo corpo è sempre il problema di qualcuno nei loro anni settanta", che a 40-50 anni di età non è una buona notizia. Almeno un quarto stanno affrontando con lo sviluppo di problemi neurologici, formicolio, intorpidimento e dolore a carico degli arti colpiti. Ciò significa che una persona può essere in possesso di un tazza, per esempio, e la prossima cosa che so è che è caduto a terra e rotto, a causa del torpore in mano. Per questi sopravvissuti, il disastro è ancora lentamente svolgendo nel loro giorno per giorno la vita.
Grünenthal scienziati non erano solo negligenza nel non ritirare il farmaco quando i report di problemi è venuto in, o per non aver testarlo secondo gli standard del tempo, ma più che la maggior parte delle aziende erano molto ben disposti ad anticipare la possibilità che Thalidomide avrebbe causare difetti di nascita.
Grünenthal inizialmente smentito che il farmaco non era stato ampiamente testati secondo gli standard del tempo, ma una volta che lo scandalo è diventata innegabile, hanno cercato di deviare la colpa e di limitare i danni.
Nel 1961 talidomide è stata infine ritirata dopo essere stato trovato per essere un teratogan - una causa di difetti di nascita. 12 anni dopo, i Distillers Company Limited, Regno Unito Biochemicals (ora Diageo) - incaricata di distribuire il farmaco nel Regno Unito - ha raggiunto un accordo di compensazione a seguito di una battaglia legale da parte delle famiglie delle persone colpite.
Sulla base di prove mediche incomplete e le aspettative non realistiche del futuro Thalidomide sopravvissuti ha bisogno di questa soluzione si è rivelata essere ad un livello insufficiente. Con tutti i sopravvissuti Talidomide nel Regno Unito ora di età superiore ai 50 anni, non è più sufficiente per affrontare la loro crescente costo della vita, e il drammatico deterioramento della loro salute.
Fino ad oggi, la Grünenthal non hanno mai accettato la responsabilità per la sofferenza causata dal talidomide. Il 1 ° settembre 2012, il Gruppo Grünenthal ha rilasciato una dichiarazione che contiene delle scuse, affermando che esso "deplora" le conseguenze della droga, che ha portato a bambini nati senza arti nel corso del 1950 e 1960. Anche se la dichiarazione è stata accolta da alcuni sopravvissuti talidomide, non è ancora una assunzione di responsabilità. Vogliono solo vivere una vita comoda, e questo significa che Grünenthal dovrebbero essere ritenuti responsabili e pagare per il loro errore finanziario.
More History
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History
Thalidomide was created by Grünenthal in 1953 and was used in the late 1950s and early 1960s as a "wonder drug" to treat morning sickness, headaches, coughs, insomnia and colds. Thalidomide was marketed in the UK under the name Distaval in 1958, and advertisements emphasized the drug's complete safety, using phrases such as “non-toxic” and “no known toxicity”.
However, in 1961 an Australian doctor, William McBride, wrote to the Lancet after noticing an increase in deformed babies being born at his hospital – all to mothers who had taken Thalidomide.
Between 1958 and 1962 tens of thousands of women throughout Europe found that the baby they were carrying unaccountably miscarried, or, worse, after they gave birth were told it was stillborn. Thousands more discovered that their babies had severe birth defects, missing arms, legs, or with severe reductions to these limbs, or even worse, damage to their internal organs, brain, heart, kidneys, intestines, genitals, etc. During 1962 record keepers began to count all of the children living who were born damaged by the drug. The only complete records are of those who survived long enough to participate in the national compensation schemes, which were established in Germany, Britain, Japan, Sweden and Australia in the 1970s. The difficulty in uncovering the full toll of the disaster begins with the unknown numbers of miscarriages and stillbirths (possibly up to ten times the number of live births), and the widespread practice of infanticide.
The Thalidomide injuries did not stop once the babies were born. At the age of fifty, the Thalidomide Trust’s records show that around half of all survivors are coping with chronic pain – mainly from muscles and joints (musculo-skeletal pain), largely as a result of the challenges of living with missing or damaged limbs. For many, their bodies are deteriorating far faster than able-bodied people. Several have been told words to the effect “your body is getting the problems of someone in their seventies”, which at forty to fifty years of age is not good news. At least a quarter are coping with developing neurological problems, tingling, numbness, and pain in their affected limbs. This means that a person may be holding a cup, for instance, and the next thing they know is it has fallen to the floor and broken, because of the numbness in their hand. For these survivors, the disaster is still slowly unfolding in their day-to-day lives.
Grünenthal scientists were not only negligent in failing to withdraw the drug when reports of problems came in, or for failing to test it according to the standards of the time, but more than most companies they were very well placed to anticipate the possibility that Thalidomide would cause birth defects.
Grünenthal initially denied claims that the drug hadn’t been extensively tested according to the standards of the time, but once the scandal became undeniable, they sought to deflect blame and limit damage.
In 1961 Thalidomide was eventually withdrawn after being found to be a teratogan - a cause of birth defects. 12 years later, the UK company Distillers Biochemicals Limited (now Diageo) – which was responsible for distributing the drug in the UK – reached a compensation settlement following a legal battle by the families of those affected.
Based on incomplete medical evidence and unrealistic expectations of Thalidomide survivors future needs this settlement has turned out to be at an inadequate level. With all Thalidomide survivors in the UK now over the age of 50, it is no longer sufficient to deal with their rising cost of living, and the dramatic deterioration of their health.
To this day, Grünenthal have never accepted responsibility for the suffering caused by Thalidomide. On September 1st 2012, The Grünenthal Group released a statement containing an apology, stating that it "regrets" the consequences of the drug, which led to babies being born without limbs during the 1950s and 1960s. Although the statement was welcomed by some Thalidomide survivors, it is still not an acceptance of responsibility. They just want to live a comfortable life, and that means Grünenthal should be held accountable and pay for their mistake financially.
Spanish
Historia
La talidomida fue creado por Grünenthal en 1953 y fue utilizado a finales de 1950 y principios de 1960 como una "droga milagrosa" para el tratamiento de las náuseas, dolores de cabeza, tos, insomnio y resfriados. La talidomida fue comercializada en el Reino Unido bajo el nombre Distaval en 1958, y destacó los anuncios de seguridad completa del medicamento, utilizando frases como "no tóxico" y "no hay toxicidad conocida".
Sin embargo, en 1961 un médico australiano, William McBride, escribió a la revista The Lancet después de notar un aumento en los bebés que nacen deformes en su hospital - todo a las madres que habían tomado Talidomida.
Entre 1958 y 1962, decenas de miles de mujeres de toda Europa descubrieron que el bebé que llevaban inexplicablemente abortado, o, peor aún, después de dar a luz se les dijo que estaba muerto. Miles de personas descubrieron que sus bebés nacieron con defectos congénitos graves, los brazos, las piernas, que faltan o con reducciones severas a estos miembros, o peor aún, el daño a sus órganos internos, cerebro, corazón, riñones, intestinos, genitales, etc Durante 1962 guardianes de los registros empezó a contar toda la vida los niños que nacieron dañado por la droga. Los únicos registros completos son de los que sobrevivieron lo suficiente como para participar en los sistemas nacionales de indemnización, que se establecieron en Alemania, Gran Bretaña, Japón, Suecia y Australia en la década de 1970. La dificultad para descubrir el número de víctimas del desastre comienza con los números desconocidos de abortos involuntarios y mortinatos (posiblemente hasta diez veces el número de nacidos vivos), y la práctica generalizada del infanticidio.
Las lesiones de la talidomida no se detuvo una vez que los bebés nacieron. A la edad de cincuenta años, los registros de la confianza talidomida muestran que cerca de la mitad de todos los sobrevivientes están lidiando con el dolor crónico - principalmente de músculos y articulaciones (dolor musculoesquelético), en gran parte como resultado de los desafíos de vivir con la falta o ramas dañadas. Para muchos, sus cuerpos se deterioran mucho más rápido que las personas sanas. Algunos han dicho palabras en el sentido de "su cuerpo está recibiendo los problemas de alguien en los setenta", que a los cuarenta o cincuenta años de edad no es una buena noticia. Al menos una cuarta están lidiando con el desarrollo de problemas neurológicos, hormigueo, entumecimiento y dolor en las extremidades afectadas. Esto significa que una persona puede ser la celebración de una taza, por ejemplo, y lo siguiente que sé es que ha caído al suelo y se rompe, debido a la sensación de adormecimiento en la mano. Para estos sobrevivientes, el desastre está siendo poco a poco se desarrolla en su día a día.
Grünenthal científicos no sólo fueron negligentes al no haber retirado la droga cuando los informes de problemas de vino, o por no probarlo de acuerdo a los estándares de la época, pero más que la mayoría de las empresas que estaban muy bien situados para prever la posibilidad de que la talidomida haría causar defectos de nacimiento.
Grünenthal inicialmente negó las acusaciones de que el medicamento no ha sido ampliamente probado de acuerdo con los estándares de la época, pero una vez que el escándalo se hizo innegable, trataron de desviar la culpa y limitar el daño.
En 1961, la talidomida fue finalmente retirada después de haber sido encontrado para ser un teratogan - una de las causas de los defectos congénitos. 12 años después, el Reino Unido, Distillers Company Limited (ahora Bioquímicos Diageo) - encargada de la distribución de la droga en el Reino Unido - llegó a un acuerdo de compensación después de una batalla legal por las familias de los afectados.
Sobre la base de evidencia incompleta médica y expectativas poco realistas de la talidomida futuro sobrevivientes necesita esta solución ha resultado ser en un nivel adecuado. Con todos los sobrevivientes de la talidomida en el Reino Unido ahora más de 50 años de edad, ya no es suficiente para hacer frente a su creciente costo de vida, y el dramático deterioro de su salud.
A día de hoy, Grünenthal nunca ha aceptado la responsabilidad por el sufrimiento causado por la talidomida. El 1 de septiembre de 2012, el Grupo Grünenthal emitió una declaración que contenga una disculpa, diciendo que "lamenta" las consecuencias de la droga, lo que llevó a los bebés que nacen sin extremidades durante los años 1950 y 1960. Aunque la declaración fue bien recibida por algunos sobrevivientes de la talidomida, no es todavía una aceptación de responsabilidad. Ellos sólo quieren vivir una vida cómoda, y eso quiere decir Grünenthal deben rendir cuentas y pagar por su error financieramente.
Italian
Storia
La talidomide è stato creato da Grünenthal nel 1953 ed è stato utilizzato alla fine del 1950 e 1960 come un "farmaco miracoloso" per curare la malattia di mattina, mal di testa, tosse, insonnia e raffreddori. La talidomide è stato commercializzato nel Regno Unito con il nome di Distaval nel 1958, e la pubblicità ha sottolineato sicurezza del farmaco, con frasi come "non tossico" e "nessuna tossicità conosciuto".
Tuttavia, nel 1961 un medico australiano, William McBride, ha scritto al Lancet dopo aver notato un aumento delle nascite di bimbi malformati essendo nati a suo ospedale - tutti da madri che avevano assunto talidomide.
Tra il 1958 e il 1962 decine di migliaia di donne in tutta Europa ha scoperto che il bambino che portavano inspiegabilmente abortito, o, peggio, dopo che ha dato alla luce hanno detto che era morto. Altre migliaia hanno scoperto che i loro bambini hanno gravi difetti di nascita, braccia, gambe, mancanti o con gravi riduzioni a queste arti, o peggio ancora, danni ai loro organi interni, cervello, cuore, reni, intestino, genitali, ecc Nel 1962 custodi record cominciò a contare tutta la vita i bambini che sono nati danneggiati dal farmaco. Le uniche registrazioni complete sono di coloro che sono sopravvissuti abbastanza a lungo per partecipare ai sistemi di indennizzo nazionali, che sono stati stabiliti in Germania, Gran Bretagna, Giappone, Svezia e Australia nel 1970. La difficoltà nello scoprire il bilancio del disastro inizia con i numeri sconosciuti di aborti spontanei e nati morti (forse fino a dieci volte il numero di nati vivi), e la pratica diffusa di infanticidio.
Le lesioni Talidomide non si è fermata una volta che i bambini sono nati. All'età di 50, del Trust talidomide i tabulati mostrano che circa la metà di tutti i sopravvissuti stanno affrontando con dolore cronico - principalmente da muscoli e le articolazioni (il dolore muscoloscheletrico), soprattutto a causa delle sfide della vita con mancanti o arti danneggiati. Per molti, i loro corpi si stanno deteriorando molto più veloce di persone abili. Molti hanno detto parole per l'effetto "il tuo corpo è sempre il problema di qualcuno nei loro anni settanta", che a 40-50 anni di età non è una buona notizia. Almeno un quarto stanno affrontando con lo sviluppo di problemi neurologici, formicolio, intorpidimento e dolore a carico degli arti colpiti. Ciò significa che una persona può essere in possesso di un tazza, per esempio, e la prossima cosa che so è che è caduto a terra e rotto, a causa del torpore in mano. Per questi sopravvissuti, il disastro è ancora lentamente svolgendo nel loro giorno per giorno la vita.
Grünenthal scienziati non erano solo negligenza nel non ritirare il farmaco quando i report di problemi è venuto in, o per non aver testarlo secondo gli standard del tempo, ma più che la maggior parte delle aziende erano molto ben disposti ad anticipare la possibilità che Thalidomide avrebbe causare difetti di nascita.
Grünenthal inizialmente smentito che il farmaco non era stato ampiamente testati secondo gli standard del tempo, ma una volta che lo scandalo è diventata innegabile, hanno cercato di deviare la colpa e di limitare i danni.
Nel 1961 talidomide è stata infine ritirata dopo essere stato trovato per essere un teratogan - una causa di difetti di nascita. 12 anni dopo, i Distillers Company Limited, Regno Unito Biochemicals (ora Diageo) - incaricata di distribuire il farmaco nel Regno Unito - ha raggiunto un accordo di compensazione a seguito di una battaglia legale da parte delle famiglie delle persone colpite.
Sulla base di prove mediche incomplete e le aspettative non realistiche del futuro Thalidomide sopravvissuti ha bisogno di questa soluzione si è rivelata essere ad un livello insufficiente. Con tutti i sopravvissuti Talidomide nel Regno Unito ora di età superiore ai 50 anni, non è più sufficiente per affrontare la loro crescente costo della vita, e il drammatico deterioramento della loro salute.
Fino ad oggi, la Grünenthal non hanno mai accettato la responsabilità per la sofferenza causata dal talidomide. Il 1 ° settembre 2012, il Gruppo Grünenthal ha rilasciato una dichiarazione che contiene delle scuse, affermando che esso "deplora" le conseguenze della droga, che ha portato a bambini nati senza arti nel corso del 1950 e 1960. Anche se la dichiarazione è stata accolta da alcuni sopravvissuti talidomide, non è ancora una assunzione di responsabilità. Vogliono solo vivere una vita comoda, e questo significa che Grünenthal dovrebbero essere ritenuti responsabili e pagare per il loro errore finanziario.
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NASA's Mars Rover Curiosity acquired the above image (Figure 5) with Mars Hand Lens Imager (MAHLI) on Jan. 23, 2016 (Sol 1231) at Namib Dune in Bagnold dune field, Gale Crater, Mars. Most of the particles in this image are eroded ooids. Red lines mark some of the ooids. They measure 0.2 mm to 0.4 mm across. Image width: ~2.8 cm. Largest-sized figure:
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