APPENDIX 1. LIST OF ADVERSE EVENTS OF SPECIAL INTEREST Goodpasture's syndrome, Shock, Vasculitis gastrointestinal, Lymphocytic hypophysitis, COVID-19 treatment, Early infantile epileptic encephalopathy with burst-suppression, SARS-CoV-2 carrier, Microembolism, Pityriasis lichenoides et varioliformis acuta, SARS-CoV-2 test false positive, Cerebral artery embolism, Ophthalmic herpes zoster, Complement factor C1 decreased, VIth nerve paralysis, Vocal cord paresis, Neutropenia neonatal, Periportal oedema, Bile output abnormal, Swelling face, Cystitis interstitial, Polyarteritis nodosa, Interstitial granulomatous dermatitis, Pharyngeal swelling, Ophthalmic herpes simplex, Anti-epithelial antibody positive, Thrombosis corpora cavernosa, Lichen planus, Double stranded DNA antibody positive, Immune-mediated hypothyroidism, Herpes dermatitis, Varicella, Truncus coeliacus thrombosis, ChildPugh-Turcotte score abnormal, Young's syndrome, Autoimmune dermatitis, Death neonatal, Pharyngeal oedema, Terminal ileitis, Anti-neuronal antibody positive, Autoimmune retinopathy, Cardiac arrest, Granulomatosis with polyangiitis, Aura, Severe acute respiratory syndrome, Autoimmune colitis, Pseudovasculitis, Hantavirus pulmonary infection, Evans syndrome, Vogt-Koyanagi-Harada disease, Peritonitis lupus, Immune-mediated myocarditis, Pruritus allergic, Cryoglobulinaemia, SARS-CoV-1 test, Tachycardia, Anti-aquaporin-4 antibody positive, Hepatic vascular resistance increased, Autoimmune neutropenia, Type 1 diabetes mellitus, Hyperbilirubinaemia, Toxic epidermal necrolysis, Multifocal motor neuropathy, Renal vasculitis, Noninfective encephalitis, Spinal artery thrombosis, Convulsion in childhood, Circulatory collapse, Hypergammaglobulinaemia benign monoclonal, Anaphylactoid shock, Herpes simplex meningitis, Systemic scleroderma, Clinically isolated syndrome, Thrombotic stroke, Tubulointerstitial nephritis and uveitis syndrome, Thrombosis, Autoimmune haemolytic anaemia, Peripheral ischaemia, Birdshot chorioretinopathy, Embolism venous, Gastrointestinal amyloidosis, Anti-GAD antibody positive, Marchiafava-Bignami disease, Eczema herpeticum, Ulcerative keratitis, Rheumatoid arthritis, Dermatitis herpetiformis, Perihepatic discomfort, Demyelination, SARS-CoV-2 test negative, Thrombophlebitis neonatal, Portal pyaemia, Anti-SRP antibody positive, Glomerulonephritis rapidly progressive, AST/ALT ratio abnormal, Benign familial neonatal convulsions, Pneumonia necrotising, Pneumonia, Benign rolandic epilepsy, Pre-eclampsia, Thromboplastin antibody positive, Retinal vascular thrombosis, Rheumatoid nodule, Allergic oedema, Respiratory failure, Glomerulonephritis membranoproliferative, Inflammation, CSF oligoclonal band present, Complement factor abnormal, Hypoalbuminaemia, Pulmonary amyloidosis, Urobilinogen urine increased, Chronic respiratory failure, Autoimmune neuropathy, Retinopathy, Herpes simplex visceral, Autoimmune aplastic anaemia, Immune-mediated pneumonitis, Anti-ganglioside antibody positive, Post viral fatigue syndrome, Spondylitis, VIth nerve paresis, Leukopenia, Change in seizure presentation, Arterial bypass thrombosis, Total bile acids increased, Retinal artery occlusion, Anti-actin antibody positive, Arteriovenous fistula thrombosis, Penile vein thrombosis, Lambl's excrescences, Meningitis herpes, Endocrine ophthalmopathy, Antigliadin antibody positive, Administration site vasculitis, Morvan syndrome, Endotracheal intubation, De novo purine synthesis inhibitors associated acute inflammatory syndrome, Oesophageal achalasia, Tonic posturing, Renal artery thrombosis, Lung abscess, Cranial nerve paralysis, Pneumonia respiratory syncytial viral, Autoimmune disorder, Panencephalitis, Gastritis herpes, Urticarial vasculitis, Autoimmune pericarditis, Acute encephalitis with refractory, repetitive partial seizures, Splenic embolism, Mitochondrial aspartate aminotransferase increased, Embolic cerebellar infarction, Schizencephaly, Peritoneal fluid protein decreased, Tongue amyloidosis, Immune-mediated myositis, Haemorrhagic vasculitis, Corpus callosotomy, Chillblains, Cerebral arteritis, Meningoencephalitis herpetic, Stillbirth, Infected vasculitis, Anti-glomerular basement membrane antibody positive, Subclavian artery thrombosis, Cerebral amyloid angiopathy, SARS-CoV-2 antibody test, Lichen sclerosus, Pruritus, Amyloid arthropathy, Varicella zoster virus infection, XIth nerve paralysis, Mouth swelling, Herpes zoster, SARS-CoV-1 test negative, Trigeminal neuralgia, Hepatosplenomegaly, SARS-CoV-2 test, Lower respiratory tract herpes infection, Lupus pneumonitis, Catheter site vasculitis, Hepatic mass, Moyamoya disease, Palindromic rheumatism, SARS-CoV-2 viraemia, Aortic thrombosis, Herpes simplex otitis externa, Neutropenic sepsis, Anti-vimentin antibody positive, Paracancerous pneumonia, Systemic lupus erythematosus, Acoustic neuritis, Oedema, Double cortex syndrome, Metapneumovirus infection, Respiratory paralysis, Rheumatoid factor quantitative increased, Application site vasculitis, Migraine-triggered seizure, Myoclonic epilepsy and ragged-red fibres, Pemphigus, Herpes simplex encephalitis, Oral herpes, Respiratory arrest, Suspected COVID19, Bickerstaff's encephalitis, Chronic inflammatory demyelinating polyradiculoneuropathy, Anti-NMDA antibody positive, Alanine aminotransferase increased, Hoigne's syndrome, Acute haemorrhagic oedema of infancy, Immune-mediated hepatitis, Rheumatic brain disease, Neonatal lupus erythematosus, Lhermitte's sign, Myocardial infarction, Myasthenia gravis neonatal, Chronic recurrent multifocal osteomyelitis, Enterocolitis, Congenital varicella infection, Drug withdrawal convulsions, Renal amyloidosis, Guanase increased, Myocarditis, Molybdenum cofactor deficiency, Scleroderma-like reaction, Autoimmune blistering disease, Pyostomatitis vegetans, Anti-insulin antibody increased, Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids, Sudden unexplained death in epilepsy, Kayser-Fleischer ring, Peripheral vein thrombus extension, Coronary artery thrombosis, Type I hypersensitivity, Neonatal mucocutaneous herpes simplex, Aspartate-glutamate-transporter deficiency, Medical device site vasculitis, Periorbital swelling, Nodular vasculitis, Cerebrovascular accident, Vascular purpura, Hypogammaglobulinaemia, Varicella post vaccine, Tonic clonic movements, Generalised tonic-clonic seizure, Arterial thrombosis, Anti-cyclic citrullinated peptide antibody positive, Parietal cell antibody positive, Vessel puncture site thrombosis, Portosplenomesenteric venous thrombosis, Glutamate dehydrogenase increased, Acute myocardial infarction, Pulmonary artery thrombosis, Thrombophlebitis superficial, Irregular breathing, Tumefactive multiple sclerosis, Liver function test abnormal, Embolic pneumonia, Autoimmune cholangitis, Polymyalgia rheumatica, Product availability issue, Tracheobronchitis, Chronic fatigue syndrome, Leukoencephalopathy, Herpes zoster meningomyelitis, Acute respiratory failure, Shock symptom, Facial paresis, Rash erythematous, Venous recanalisation, Miliary pneumonia, Cardio-respiratory arrest, Parainfluenzae viral laryngotracheobronchitis, Hepatic vein embolism, Ophthalmic artery thrombosis, Injection site thrombosis, Spontaneous heparin-induced thrombocytopenia syndrome, SARS-CoV-2 antibody test positive, Scleroderma renal crisis, Ketosisprone diabetes mellitus, Autoimmune demyelinating disease, Splenic vein thrombosis, Neutropenic colitis, Aspartate aminotransferase increased, Pneumonia mycoplasmal, Superior sagittal sinus thrombosis, Antiphospholipid antibodies positive, Human herpesvirus 6 encephalitis, Antisynthetase syndrome, Intracardiac thrombus, Basilar artery thrombosis, Anti-sperm antibody positive, Mesenteric vein thrombosis, Herpes simplex reactivation, Infusion site vasculitis, Haemolytic anaemia, Mononeuropathy multiplex, Cardiopulmonary failure, Autoimmune arthritis, Device embolisation, Laryngeal rheumatoid arthritis, Ageusia, Acute flaccid myelitis, Colitis, Aortitis, Oedema blister, Heparin-induced thrombocytopenia, Lupoid hepatic cirrhosis, Tuberous sclerosis complex, Multiple subpial transection, Cerebral venous sinus thrombosis, Congenital anomaly, Ataxia, Dyspnoea, Myelitis, MERS-CoV test, Administration site thrombosis, Psoriasis, Cardiolipin antibody positive, Herpes gestationis, Polymicrogyria, Chronic autoimmune glomerulonephritis, Antiviral prophylaxis, Subacute cutaneous lupus erythematosus, Thrombophlebitis, Lupus pancreatitis, Ammonia increased, Aseptic cavernous sinus thrombosis, Focal cortical resection, Blood pressure decreased, Vasculitic rash, Haemorrhagic pneumonia, Autoimmune lymphoproliferative syndrome, Infantile genetic agranulocytosis, Disseminated neonatal herpes simplex, Collagen disorder, Deep vein thrombosis postoperative, Foaming at mouth, Coronary bypass thrombosis, Ankylosing spondylitis, COVID-19 immunisation, Aspartate aminotransferase abnormal, IPEX syndrome, Foreign body embolism, Encephalopathy, Lupus endocarditis, Palpable purpura, Haemorrhagic disorder, Galactose elimination capacity test abnormal, Alveolar proteinosis, Vascular graft thrombosis, Choking sensation, Herpes virus infection, Polyglandular autoimmune syndrome type I, Ammonia abnormal, Carotid arterial embolus, Benign ethnic neutropenia, Amyloidosis, Myocarditis post infection, Acquired epidermolysis bullosa, Meningoencephalitis herpes simplex neonatal, Neuritis, Post thrombotic retinopathy, Acute disseminated encephalomyelitis, Herpetic radiculopathy, Dermatitis, Implant site thrombosis, Immune-mediated neuropathy, Anaphylactoid syndrome of pregnancy, Urticaria, Polyglandular disorder, Cranial nerve palsies multiple, Immune-mediated thyroiditis, Still's disease, Pneumonia influenzal, Retroperitoneal fibrosis, Eye swelling, Cardiogenic shock, Herpes zoster pharyngitis, Anti-neutrophil cytoplasmic antibody positive vasculitis, Lupus hepatitis, Intrinsic factor antibody positive, Autoimmune hyperlipidaemia, Embolic stroke, Bronchitis, Hypertransaminasaemia, Meningitis aseptic, Alloimmune hepatitis, Encephalitis haemorrhagic, Bronchitis viral, Post thrombotic syndrome, Anaphylactic transfusion reaction, Antinuclear antibody positive, Retinal vein occlusion, Eye pruritus, Myositis, SARS-CoV-2 sepsis, Wheezing, Glomerulonephritis membranous, SARSCoV-2 test positive, Arteritis coronary, Occupational exposure to communicable disease, Patient isolation, Autoimmune lung disease, Hepatic fibrosis marker increased, Noninfectious myelitis, Paraneoplastic dermatomyositis, Thrombophlebitis migrans, Myasthenia gravis crisis, Brain stem embolism, Susac's syndrome, Galactose elimination capacity test decreased, Periorbital oedema, Insulin autoimmune syndrome, Drop attacks, Eosinopenia, Computerised tomogram liver abnormal, Varicella zoster gastritis, Disseminated varicella zoster virus infection, Respiratory syncytial virus bronchitis, Immune-mediated nephritis, Pulmonary sepsis, Hepatic function abnormal, Cardiac failure acute, Warm type haemolytic anaemia, Haemophagocytic lymphohistiocytosis, Polyneuropathy idiopathic progressive, Linear IgA disease, Oedema mouth, Grey matter heterotopia, Rheumatoid factor positive, SARS-CoV-2 antibody test negative, Systemic sclerosis pulmonary, Anti-glomerular basement membrane disease, Anti-interferon antibody positive, Encephalitis allergic, Rheumatoid vasculitis, Hypersensitivity, Varicella zoster pneumonia, Epilepsy surgery, Idiopathic CD4 lymphocytopenia, COVID-19 pneumonia, Antiinsulin receptor antibody positive, Papillophlebitis, SLE arthritis, Aortic embolus, Acute motor-sensory axonal neuropathy, Rasmussen encephalitis, Stoma site vasculitis, Autoimmune thyroiditis, Juvenile psoriatic arthritis, Neuromyelitis optica pseudo relapse, Neuromyelitis optica spectrum disorder, CDKL5 deficiency disorder, Undifferentiated connective tissue disease, IVth nerve paralysis, Progressive facial hemiatrophy, Postpericardiotomy syndrome, MERS-CoV test positive, Nasal herpes, Microscopic polyangiitis, Hypersensitivity vasculitis, Paradoxical embolism, Lower respiratory tract infection viral, Saccadic eye movement, AST to platelet ratio index increased, Post procedural pneumonia, Renal vein embolism, Laryngospasm, Acute respiratory distress syndrome, HenochSchonlein purpura nephritis, Acute macular outer retinopathy, Necrotising herpetic retinopathy, Blood cholinesterase abnormal, Postictal state, Lupus cystitis, Pneumonia parainfluenzae viral, Proctitis ulcerative, Thrombocytopenia, Alopecia areata, Immune-mediated enterocolitis, Autoimmune heparin-induced thrombocytopenia, Ocular vasculitis, Status epilepticus, AntiVGKC antibody positive, Postictal headache, Alanine aminotransferase abnormal, Pelvic venous thrombosis, Ophthalmic vein thrombosis, Retinal artery embolism, Multiple sclerosis relapse prophylaxis, Renal vein thrombosis, Marine Lenhart syndrome, Coronavirus infection, Liver iron concentration increased, Coronary artery embolism, Anti-thyroid antibody positive, Chronic cutaneous lupus erythematosus, Hypotensive crisis, Post stroke seizure, Neuralgic amyotrophy, Optic perineuritis, Paget-Schroetter syndrome, Muscular sarcoidosis, CEC syndrome, Upper airway obstruction, Lymphocytopenia neonatal, White nipple sign, Granulocytopenia neonatal, Liver sarcoidosis, IgA nephropathy, Tongue biting, Vitiligo, Autoimmune uveitis, Complement factor C3 decreased, Psoriatic arthropathy, Crohn's disease, Juvenile myoclonic epilepsy, Herpes zoster reactivation, Blood pressure diastolic decreased, Microangiopathy, Anti-exosome complex antibody positive, Lupus vasculitis, Neuropathy, ataxia, retinitis pigmentosa syndrome, Hypoglossal nerve paresis, Transient epileptic amnesia, Immunemediated adverse reaction, Renal failure, Enteropathic spondylitis, Hypotension, Thyroiditis, Jugular vein embolism, Hypoglossal nerve paralysis, IgM nephropathy, Complement factor decreased, Band sensation, Keratoderma blenorrhagica, Preictal state, Digital pitting scar, Pneumobilia, Acquired C1 inhibitor deficiency, Ovarian vein thrombosis, Allergic bronchopulmonary mycosis, Immunemediated gastritis, Immune-mediated hepatic disorder, Transaminases abnormal, Glucose transporter type 1 deficiency syndrome, Device related thrombosis, Pneumonia measles, Rheumatic disorder, Febrile convulsion, Herpes oesophagitis, Autoimmune myocarditis, Idiopathic neutropenia, Radiation leukopenia, Metastatic pulmonary embolism, Nasal obstruction, Anti-muscle specific kinase antibody positive, Progressive multifocal leukoencephalopathy, Liver scan abnormal, Hereditary angioedema with C1 esterase inhibitor deficiency, Neuritis cranial, Post procedural pulmonary embolism, Pulmonary veno-occlusive disease, SARS-CoV-1 test positive, Magnetic resonance imaging liver abnormal, Tumour embolism, Postictal psychosis, Swelling, Herpes simplex virus conjunctivitis neonatal, Eosinophilic fasciitis, Pneumonia adenoviral, Lupus nephritis, Eclampsia, Paroxysmal nocturnal haemoglobinuria, Tongue oedema, Pulmonary sarcoidosis, Lip swelling, Hepatic enzyme decreased, JC polyomavirus test positive, Facial paralysis, Renal embolism, Optic neuritis, Herpes simplex colitis, Reactive capillary endothelial proliferation, Cerebral septic infarct, Seizure anoxic, Maternal exposure during pregnancy, Magnetic resonance proton density fat fraction measurement, Human herpesvirus 7 infection, Hyperglycaemic seizure, Myasthenia gravis, Hepatic enzyme increased, Manufacturing production issue, Febrile infection-related epilepsy syndrome, Herpes zoster meningoradiculitis, BuddChiari syndrome, Lymphopenia, Blood alkaline phosphatase increased, Venous thrombosis neonatal, Alcoholic seizure, Cataplexy, Anti-interferon antibody negative, Oral lichen planus, Child-Pugh-Turcotte score increased, Primary progressive multiple sclerosis, Pulmonary haemorrhage, Postoperative respiratory failure, Smooth muscle antibody positive, Myelitis transverse, Postural orthostatic tachycardia syndrome, Temporal lobe epilepsy, Noninfective oophoritis, Eosinophilic granulomatosis with polyangiitis, Antiribosomal P antibody positive, Herpes zoster meningoencephalitis, Colitis microscopic, Acute haemorrhagic leukoencephalitis, Pulmonary embolism, Liver iron concentration abnormal, Immune-mediated encephalopathy, Meningomyelitis herpes, Anti-prothrombin antibody positive, SAPHO syndrome, Polyglandular autoimmune syndrome type II, Human herpesvirus 6 infection, Quarantine, Neonatal pneumonia, Acute motor axonal neuropathy, Chronic gastritis, Meningitis, Multisystem inflammatory syndrome in children, Thrombotic cerebral infarction, Hepatic lymphocytic infiltration, Erythema nodosum, Juvenile idiopathic arthritis, Application site thrombosis, Vascular pseudoaneurysm thrombosis, Basedow's disease, Axonal neuropathy, Bilirubin conjugated increased, Blood cholinesterase decreased, Lupus myositis, Vena cava thrombosis, Autoimmune inner ear disease, Choking, Hepatomegaly, H ypocalcaemic seizure, IIIrd nerve paresis, Cogan's syndrome, Eosinophilic oesophagitis, Transaminases increased, Acute cutaneous lupus erythematosus, Complement factor C4 decreased, Immune-mediated cholangitis, Proctitis herpes, Thrombosis mesenteric vessel, Liver injury, Diffuse vasculitis, Anti-saccharomyces cerevisiae antibody test positive, Latent autoimmune diabetes in adults, Cavernous sinus thrombosis, IIIrd nerve paralysis, Cutaneous vasculitis, Clonic convulsion, Genital herpes simplex, Henoch-Schonlein purpura, Laryngeal oedema, Autoimmune enteropathy, Generalised onset non-motor seizure, Epileptic psychosis, Immunoglobulins abnormal, CREST syndrome, Visceral venous thrombosis, Ocular myasthenia, Face oedema, Eye oedema, Erythema, Cardio-respiratory distress, Aplastic anaemia, Coronavirus test positive, Immune-mediated cholestasis, Cardiac sarcoidosis, Femoral artery embolism, Dermatitis bullous, Lennox-Gastaut syndrome, Anti-glycyl-tRNA synthetase antibody positive, Paraneoplastic pemphigus, Scleroderma associated digital ulcer, Portal vein flow decreased, Atypical pneumonia, Pneumonia cytomegaloviral, Pulmonary thrombosis, Raynaud's phenomenon, Enterobacter pneumonia, Throat tightness, Respiratory disorder, Alpers disease, Antimitochondrial antibody positive, Scleritis, Partial seizures, Anti-VGCC antibody positive, Cardiac amyloidosis, Chest discomfort, Circumoral oedema, Arthritis enteropathic, Limbic encephalitis, Thrombotic thrombocytopenic purpura, Blood bilirubin abnormal, Caesarean section, Asthma, Polymyositis, Atrophic thyroiditis, Stridor, Liver induration, Swollen tongue, Pericarditis lupus, Herpes simplex pharyngitis, Lupus enteritis, Instillation site thrombosis, Juvenile spondyloarthritis, Amygdalohippocampectomy, Subacute inflammatory demyelinating polyneuropathy, Umbilical cord thrombosis, Cutaneous amyloidosis, Cerebral microembolism, Thromboangiitis obliterans, Hemimegalencephaly, Hepatic artery embolism, Coombs positive haemolytic anaemia, Hepatitis, Embolism arterial, Deja vu, Cyclic neutropenia, Postoperative thrombosis, LE cells present, Biliary ascites, Anti-IA2 antibody positive, Polyneuropathy, Middle East respiratory syndrome, Pulmonary renal syndrome, Pulmonary microemboli, Hyperammonaemia, Radiologically isolated syndrome, Transverse sinus thrombosis, Multiple sclerosis, Procedural shock, Oculofacial paralysis, Diabetic ketoacidosis, Concentric sclerosis, Precerebral artery thrombosis, Secondary progressive multiple sclerosis, Anaphylactic reaction, Rash, Encephalomyelitis, POEMS syndrome, Enteritis, Urine bilirubin increased, Reversible airways obstruction, Severe myoclonic epilepsy of infancy, Hypercholia, Bile output decreased, Arrhythmia, Axonal and demyelinating polyneuropathy, Venous thrombosis limb, Immune thrombocytopenia, Antineutrophil cytoplasmic antibody increased, Thyroid stimulating immunoglobulin increased, Beta-2 glycoprotein antibody positive, Encephalitis autoimmune, Systemic lupus erythematosus rash, Myokymia, Inflammatory bowel disease, Hepatic artery thrombosis, Nephrogenic systemic fibrosis, Herpes zoster meningitis, Aplasia pure red cell, Cold agglutinins positive, Stiff person syndrome, Brachiocephalic vein thrombosis, Cerebral venous thrombosis, Injection site vasculitis, Arteriovenous graft site stenosis, Mixed connective tissue disease, Cardiac ventricular thrombosis, Disseminated varicella, Hepatic enzyme abnormal, Hepatic vascular thrombosis, Interstitial lung disease, Cardiovascular insufficiency, Diabetic mastopathy, Injection site urticaria, Respiratory syncytial virus bronchiolitis, Genital herpes, Embolic cerebral infarction, Sensation of foreign body, Anti-myelin-associated glycoprotein associated polyneuropathy, Sarcoidosis, Immune-mediated uveitis, MAGIC syndrome, Varicella zoster oesophagitis, Autoimmune hepatitis, Autoimmune nephritis, Sjogren's syndrome, Calcium embolism, Rash pruritic, Hepatic artery flow decreased, Pulmonary tumour thrombotic microangiopathy, Polyarthritis, Endocrine disorder, Retinol binding protein decreased, Faciobrachial dystonic seizure, Mesenteric artery thrombosis, Uveitis, Intrapericardial thrombosis, Acute febrile neutrophilic dermatosis, Toxic leukoencephalopathy, Paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection, Dialysis membrane reaction, Overlap syndrome, Herpes sepsis, Blue toe syndrome, Addison's disease, CSWS syndrome, Encephalitis post immunisation, Hepatobiliary scan abnormal, Rheumatoid scleritis, Shunt thrombosis, Arteritis, Cytokine release syndrome, Cranial nerve disorder, Rheumatoid nodule removal, 1p36 deletion syndrome, Disseminated intravascular coagulation, Vasculitic ulcer, Partial seizures with secondary generalisation, Product supply issue, Ultrasound liver abnormal, Cerebellar embolism, Occupational exposure to SARS-CoV-2, Immune-mediated cytopenia, Chronic spontaneous urticaria, Varicella zoster sepsis, Herpes simplex necrotising retinopathy, Lichen planopilaris, Swelling of eyelid, Spinal artery embolism, Uhthoff's phenomenon, Pleuroparenchymal fibroelastosis, Anti-myelin-associated glycoprotein antibodies positive, Blood bilirubin unconjugated increased, Transfusion-related alloimmune neutropenia, Seizure like phenomena, Lewis-Sumner syndrome, Laryngeal dyspnoea, Renal arteritis, Frontal lobe epilepsy, IRVAN syndrome, Catheter site thrombosis, Felty's syndrome, Haemorrhagic varicella syndrome, Arthritis, Idiopathic pulmonary fibrosis, Anti-platelet antibody positive, Human herpesvirus 8 infection, Segmented hyalinising vasculitis, Osmotic demyelination syndrome, Liver function test decreased, Blood pressure systolic decreased, Leukopenia neonatal, X-ray hepatobiliary abnormal, Adverse event following immunisation, Portal vein thrombosis, Renal vascular thrombosis, Epileptic aura, Dreamy state, Primary amyloidosis, Intracardiac mass, Venous thrombosis, Molar ratio of total branched-chain amino acid to tyrosine, Placenta praevia, Tracheal obstruction, Bronchial oedema, Cyanosis, Retrograde portal vein flow, Collagen-vascular disease, Ocular hyperaemia, Benign familial pemphigus, Postoperative respiratory distress, Autoinflammation with infantile enterocolitis, Giant cell arteritis, Vena cava embolism, Cerebellar artery thrombosis, Rheumatoid lung, Foetal placental thrombosis, Product distribution issue, Herpes simplex meningoencephalitis, Liver function test increased, Stevens-Johnson syndrome, Vasculitis necrotising, Cutaneous sarcoidosis, Anti-HLA antibody test positive, Gelastic seizure, Erythema multiforme, Scleroderma, Circumoral swelling, Glomerulonephritis, Infective thrombosis, Neuronal neuropathy, Pulmonary oil microembolism, Anti-basal ganglia antibody positive, Herpes zoster necrotising retinopathy, Eyelid oedema, Expanded disability status scale score decreased, Vertebral artery thrombosis, Mononeuritis, Axillary vein thrombosis, Atrial thrombosis, Herpes simplex oesophagitis, Exposure to SARS-CoV-2, Multiple sclerosis relapse, Radiculitis brachial, Venous thrombosis in pregnancy, Convulsive threshold lowered, Lupus pleurisy, Hashitoxicosis, Mesangioproliferative glomerulonephritis, Amniotic cavity infection, Anti-insulin receptor antibody increased, COVID-19 prophylaxis, Hepatic hydrothorax, Nephritis, Satoyoshi syndrome, Oedema due to hepatic disease, Granulocytopenia, Convulsions local, Pernicious anaemia, Thrombosis in device, Subclavian artery embolism, Seizure cluster, Hepatic sequestration, Disseminated intravascular coagulation in newborn, Pemphigoid, Cutaneous lupus erythematosus, Kaposi sarcoma inflammatory cytokine syndrome, Neuropathy peripheral, Embolia cutis medicamentosa, Polyglandular autoimmune syndrome type III, Polychondritis, Lafora's myoclonic epilepsy, Skin swelling, Dressler's syndrome, Deep vein thrombosis, Retinal vein thrombosis, Epidermolysis, Tumour thrombosis, Lupus myocarditis, Immune-mediated endocrinopathy, Encephalitis brain stem, Herpes simplex sepsis, MERS-CoV test negative, Relapsing-remitting multiple sclerosis, Autoimmune eye disorder, Systemic lupus erythematosus disease activity index decreased, Fibromyalgia, Autoimmune endocrine disorder, Simple partial seizures, Herpes simplex cervicitis, Haemorrhagic ascites, Colitis erosive, Peritoneal fluid protein abnormal, Adrenal thrombosis, Hepatic venous pressure gradient increased, Tonic convulsion, Neonatal Crohn's disease, Pyrexia, Behcet's syndrome, Liver palpable, Autoimmune encephalopathy, Stress cardiomyopathy, Anosmia, Rheumatoid factor increased, Antiviral treatment, Lupus-like syndrome, Anaphylactoid reaction, Arteriovenous graft thrombosis, Seizure, Vasculitis, C1q nephropathy, JC virus CSF test positive, Complement factor C2 decreased, Monocytopenia, Anti-zinc transporter 8 antibody positive, Thrombocytopenic purpura, Focal dyscognitive seizures, Hypoglycaemic seizure, Tachypnoea, Marburg's variant multiple sclerosis, Coronavirus test, Amyloidosis senile, Trigeminal nerve paresis, Toxic oil syndrome, Petit mal epilepsy, Blood alkaline phosphatase abnormal, DNA antibody positive, Herpes simplex meningomyelitis, Coronary artery disease, Cerebrospinal thrombotic tamponade, Peripheral embolism, Neonatal seizure, Rheumatoid neutrophilic dermatosis, Idiopathic interstitial pneumonia, Cold type haemolytic anaemia, Portal vein embolism, Asymptomatic COVID19, Encephalitis periaxialis diffusa, Immunemediated hyperthyroidism, Histone antibody positive, Exanthema subitum, Herpes simplex gastritis, Agranulocytosis, Febrile neutropenia, Oropharyngeal spasm, Erythema induratum, Lupus encephalitis, Hyperventilation, Uncinate fits, Exposure to communicable disease, Manufacturing laboratory analytical testing issue, Hyponatraemic seizure, Premature menopause, Dermatomyositis, Shrinking lung syndrome, Cement embolism, Liver opacity, Tracheobronchitis viral, Fulminant type 1 diabetes mellitus, B-cell aplasia, Postictal paralysis, Cholangitis sclerosing, Herpes ophthalmic, Hepatic pain, Neonatal epileptic seizure, Progressive relapsing multiple sclerosis, Infusion site thrombosis, Model for end stage liver disease score increased, Septic pulmonary embolism, Neutropenia, Jeavons syndrome, Biopsy liver abnormal, Portal vein pressure increased, Pneumonia viral, Thrombotic microangiopathy, Prosthetic cardiac valve thrombosis, Pyoderma gangrenosum, Seizure prophylaxis, Varicella keratitis, Primary biliary cholangitis, Pulmonary venous thrombosis, Brain stem thrombosis, Infantile spasms, Leucine aminopeptidase increased, Granulomatous dermatitis, Hepatic amyloidosis, Human herpesvirus 6 infection reactivation, Oropharyngeal oedema, Anti-transglutaminase antibody increased, Hypoxia, 5'nucleotidase increased, Urobilinogen urine decreased, Central nervous system lupus, Anti-islet cell antibody positive, Angioedema, Herpes zoster cutaneous disseminated, Retinal artery thrombosis, Uterine rupture, Palisaded neutrophilic granulomatous dermatitis, Obstetrical pulmonary embolism, Medical device site thrombosis, Herpes simplex viraemia, Subclavian vein thrombosis, Liver tenderness, Herpes simplex, Autoantibody positive, Postpartum venous thrombosis, Immune-mediated pancreatitis, Enteritis leukopenic, Gamma-glutamyltransferase increased, Neuropsychiatric lupus, Automatism epileptic, Stoma site thrombosis, Venous intravasation, MELAS syndrome, GuillainBarre syndrome, Herpes zoster infection neurological, Dialysis amyloidosis, Autoimmune thyroid disorder, Tracheobronchitis mycoplasmal, Acquired epileptic aphasia, Neutropenic infection, Atypical benign partial epilepsy, Septic embolus, Coeliac disease, Fibrillary glomerulonephritis, Post stroke epilepsy, Capillaritis, Ocular pemphigoid, Demyelinating polyneuropathy, Lip oedema, Immune-mediated encephalitis, Acute kidney injury, Mesenteric artery embolism, Secondary cerebellar degeneration, SARSCoV-2 test false negative, Genital herpes zoster, Cerebral thrombosis, Immunoglobulin G4 related disease, Foetal distress syndrome, Diastolic hypotension, Testicular autoimmunity, Angiopathic neuropathy, Air embolism, Bromosulphthalein test abnormal, Gamma-glutamyltransferase abnormal, Atonic seizures, Palmoplantar keratoderma, Noninfective encephalomyelitis, Bronchopulmonary aspergillosis allergic, Post-traumatic epilepsy, Bronchospasm, Topectomy, Expanded disability status scale score increased, Blood bilirubin increased, Anti-RNA polymerase III antibody positive, Arterial bypass occlusion, Coronavirus test negative, Secondary amyloidosis, Caplan's syndrome, Diabetes mellitus, Peritoneal fluid protein increased, Biotinidase deficiency, Graft thrombosis, Foetor hepaticus, Vasa praevia, Autoimmune anaemia, Silent thyroiditis, Colitis ulcerative, Vagus nerve paralysis, Iliac artery embolism, Ocular sarcoidosis, Bacterascites, Herpes pharyngitis, Postpartum thrombosis, Juvenile polymyositis, Autoimmune pancreatitis, Relapsing multiple sclerosis, Atheroembolism, Laryngotracheal oedema, Trigeminal palsy, Hepaplastin decreased, Autoimmune myositis, Cerebral artery thrombosis, Bilirubin conjugated abnormal, Antimyocardial antibody positive, Autonomic seizure, Antiphospholipid syndrome, Bulbar palsy, IVth nerve paresis, Basophilopenia, Sympathetic ophthalmia, Hepatic hypertrophy, Thyroid disorder, Herpes zoster oticus, Epilepsy with myoclonic-atonic seizures, Subacute endocarditis, Congestive hepatopathy, GM2 gangliosidosis, Retinal vasculitis, Zika virus associated Guillain Barre syndrome. Low birth weight baby, Post procedural hypotension, Vascular stent thrombosis, Congenital myasthenic syndrome, Thrombophlebitis septic, Autoimmune hypothyroidism, Anti-erythrocyte antibody positive, Stiff leg syndrome, Lemierre syndrome, Splenic thrombosis, Inclusion body myositis, Cytokine storm, Autonomic nervous system imbalance, Central nervous system vasculitis, Kawasaki's disease, Metastatic cutaneous Crohn's disease, Autoinflammatory disease, Fat embolism, Systemic lupus erythematosus disease activity index increased, Hepatic vein thrombosis, Pneumonia herpes viral, Takayasu's arteritis, Arthralgia, Idiopathic generalised epilepsy, AntiGAD antibody negative, Epilepsy, Cough, Neurosarcoidosis, Congenital bilateral perisylvian syndrome, Bilirubin urine present, Autoimmune pancytopenia, Hepatic venous pressure gradient abnormal, Congenital herpes simplex infection, Ascites, Mahler sign, Paresis cranial nerve, Intracranial pressure increased, Immune-mediated renal disorder, Vaccination site thrombosis, Pulmonary vasculitis, Hypothyroidism, Mastocytic enterocolitis, Butterfly rash, Tracheal oedema, Anaphylactic shock, Oropharyngeal swelling, Pulmonary fibrosis, Reynold's syndrome, Cryofibrinogenaemia, Cardiac failure, Pancreatitis, Jugular vein thrombosis, Miller Fisher syndrome, Kounis syndrome, Morphoea, Manufacturing materials issue, Cerebral gas embolism, Sclerodactylia, Hepatic fibrosis marker abnormal, Pericarditis, Baltic myoclonic epilepsy, Paraneoplastic thrombosis, Myasthenic syndrome, Type III immune complex mediated reaction, Leukoencephalomyelitis, Urticaria papular, Hashimoto's encephalopathy, Progressive multiple sclerosis, Neuromyotonia, Disseminated varicella zoster vaccine virus infection, 2-Hydroxyglutaric aciduria, Optic neuropathy, Lower respiratory tract infection, Nodular rash, Encephalitis, Hepatic hypoperfusion, Hyperthyroidism, Hypothenar hammer syndrome, COVID-19, Vaccination site vasculitis, Splenic artery thrombosis, Cough variant asthma, Herpes simplex hepatitis, Respiratory distress, Spondyloarthropathy, Vocal cord paralysis, Embolism, Glossopharyngeal nerve paralysis, Model for end stage liver disease score abnormal, Peripheral artery thrombosis, Narcolepsy, Bronchitis mycoplasmal, Antinuclear antibody increased, Multiple organ dysfunction syndrome, Glycocholic acid increased, Premature labour, Herpes simplex pneumonia, Haemorrhage, Antiacetylcholine receptor antibody positive, Colitis herpes, Flushing, Carotid artery thrombosis, Systemic lupus erythematosus disease activity index abnormal, Antineutrophil cytoplasmic antibody positive, Hepaplastin abnormal, Sneezing, Axial spondyloarthritis, Intrinsic factor antibody abnormal, Myoclonic epilepsy, Deficiency of bile secretion, Anti-insulin antibody positive,

How can a product with 9 pages of adverse side effects be advertised as SAFE FOR KIDS 5+

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APPENDIX 1. LIST OF ADVERSE EVENTS OF SPECIAL INTEREST 1p36 deletion syndrome;2-Hydroxyglutaric aciduria;5'nucleotidase increased;Acoustic neuritis;Acquired C1 inhibitor deficiency;Acquired epidermolysis bullosa;Acquired epileptic aphasia;Acute cutaneous lupus erythematosus;Acute disseminated encephalomyelitis;Acute encephalitis with refractory, repetitive partial seizures;Acute febrile neutrophilic dermatosis;Acute flaccid myelitis;Acute haemorrhagic leukoencephalitis;Acute haemorrhagic oedema of infancy;Acute kidney injury;Acute macular outer retinopathy;Acute motor axonal neuropathy;Acute motor-sensory axonal neuropathy;Acute myocardial infarction;Acute respiratory distress syndrome;Acute respiratory failure;Addison's disease;Administration site thrombosis;Administration site vasculitis;Adrenal thrombosis;Adverse event following immunisation;Ageusia;Agranulocytosis;Air embolism;Alanine aminotransferase abnormal;Alanine aminotransferase increased;Alcoholic seizure;Allergic bronchopulmonary mycosis;Allergic oedema;Alloimmune hepatitis;Alopecia areata;Alpers disease;Alveolar proteinosis;Ammonia abnormal;Ammonia increased;Amniotic cavity infection;Amygdalohippocampectomy;Amyloid arthropathy;Amyloidosis;Amyloidosis senile;Anaphylactic reaction;Anaphylactic shock;Anaphylactic transfusion reaction;Anaphylactoid reaction;Anaphylactoid shock;Anaphylactoid syndrome of pregnancy;Angioedema;Angiopathic neuropathy;Ankylosing spondylitis;Anosmia;Antiacetylcholine receptor antibody positive;Anti-actin antibody positive;Anti-aquaporin-4 antibody positive;Anti-basal ganglia antibody positive;Anti-cyclic citrullinated peptide antibody positive;Anti-epithelial antibody positive;Anti-erythrocyte antibody positive;Anti-exosome complex antibody positive;AntiGAD antibody negative;Anti-GAD antibody positive;Anti-ganglioside antibody positive;Antigliadin antibody positive;Anti-glomerular basement membrane antibody positive;Anti-glomerular basement membrane disease;Anti-glycyl-tRNA synthetase antibody positive;Anti-HLA antibody test positive;Anti-IA2 antibody positive;Anti-insulin antibody increased;Anti-insulin antibody positive;Anti-insulin receptor antibody increased;Antiinsulin receptor antibody positive;Anti-interferon antibody negative;Anti-interferon antibody positive;Anti-islet cell antibody positive;Antimitochondrial antibody positive;Anti-muscle specific kinase antibody positive;Anti-myelin-associated glycoprotein antibodies positive;Anti-myelin-associated glycoprotein associated polyneuropathy;Antimyocardial antibody positive;Anti-neuronal antibody positive;Antineutrophil cytoplasmic antibody increased;Antineutrophil cytoplasmic antibody positive;Anti-neutrophil cytoplasmic antibody positive vasculitis;Anti-NMDA antibody positive;Antinuclear antibody increased;Antinuclear antibody positive;Antiphospholipid antibodies positive;Antiphospholipid syndrome;Anti-platelet antibody positive;Anti-prothrombin antibody positive;Antiribosomal P antibody positive;Anti-RNA polymerase III antibody positive;Anti-saccharomyces cerevisiae antibody test positive;Anti-sperm antibody positive;Anti-SRP antibody positive;Antisynthetase syndrome;Anti-thyroid antibody positive;Anti-transglutaminase antibody increased;Anti-VGCC antibody positive;AntiVGKC antibody positive;Anti-vimentin antibody positive;Antiviral prophylaxis;Antiviral treatment;Anti-zinc transporter 8 antibody positive;Aortic embolus;Aortic thrombosis;Aortitis;Aplasia pure red cell;Aplastic anaemia;Application site thrombosis;Application site vasculitis;Arrhythmia;Arterial bypass occlusion;Arterial bypass thrombosis;Arterial thrombosis;Arteriovenous fistula thrombosis;Arteriovenous graft site stenosis;Arteriovenous graft thrombosis;Arteritis;Arteritis

coronary;Arthralgia;Arthritis;Arthritis enteropathic;Ascites;Aseptic cavernous sinus thrombosis;Aspartate aminotransferase abnormal;Aspartate aminotransferase increased;Aspartate-glutamate-transporter deficiency;AST to platelet ratio index increased;AST/ALT ratio abnormal;Asthma;Asymptomatic COVID19;Ataxia;Atheroembolism;Atonic seizures;Atrial thrombosis;Atrophic thyroiditis;Atypical benign partial epilepsy;Atypical pneumonia;Aura;Autoantibody positive;Autoimmune anaemia;Autoimmune aplastic anaemia;Autoimmune arthritis;Autoimmune blistering disease;Autoimmune cholangitis;Autoimmune colitis;Autoimmune demyelinating disease;Autoimmune dermatitis;Autoimmune disorder;Autoimmune encephalopathy;Autoimmune endocrine disorder;Autoimmune enteropathy;Autoimmune eye disorder;Autoimmune haemolytic anaemia;Autoimmune heparin-induced thrombocytopenia;Autoimmune hepatitis;Autoimmune hyperlipidaemia;Autoimmune hypothyroidism;Autoimmune inner ear disease;Autoimmune lung disease;Autoimmune lymphoproliferative syndrome;Autoimmune myocarditis;Autoimmune myositis;Autoimmune nephritis;Autoimmune neuropathy;Autoimmune neutropenia;Autoimmune pancreatitis;Autoimmune pancytopenia;Autoimmune pericarditis;Autoimmune retinopathy;Autoimmune thyroid disorder;Autoimmune thyroiditis;Autoimmune uveitis;Autoinflammation with infantile enterocolitis;Autoinflammatory disease;Automatism epileptic;Autonomic nervous system imbalance;Autonomic seizure;Axial spondyloarthritis;Axillary vein thrombosis;Axonal and demyelinating polyneuropathy;Axonal neuropathy;Bacterascites;Baltic myoclonic epilepsy;Band sensation;Basedow's disease;Basilar artery thrombosis;Basophilopenia;B-cell aplasia;Behcet's syndrome;Benign ethnic neutropenia;Benign familial neonatal convulsions;Benign familial pemphigus;Benign rolandic epilepsy;Beta-2 glycoprotein antibody positive;Bickerstaff's encephalitis;Bile output abnormal;Bile output decreased;Biliary ascites;Bilirubin conjugated abnormal;Bilirubin conjugated increased;Bilirubin urine present;Biopsy liver abnormal;Biotinidase deficiency;Birdshot chorioretinopathy;Blood alkaline phosphatase abnormal;Blood alkaline phosphatase increased;Blood bilirubin abnormal;Blood bilirubin increased;Blood bilirubin unconjugated increased;Blood cholinesterase abnormal;Blood cholinesterase decreased;Blood pressure decreased;Blood pressure diastolic decreased;Blood pressure systolic decreased;Blue toe syndrome;Brachiocephalic vein thrombosis;Brain stem embolism;Brain stem thrombosis;Bromosulphthalein test abnormal;Bronchial oedema;Bronchitis;Bronchitis mycoplasmal;Bronchitis viral;Bronchopulmonary aspergillosis allergic;Bronchospasm;BuddChiari syndrome;Bulbar palsy;Butterfly rash;C1q nephropathy;Caesarean section;Calcium embolism;Capillaritis;Caplan's syndrome;Cardiac amyloidosis;Cardiac arrest;Cardiac failure;Cardiac failure acute;Cardiac sarcoidosis;Cardiac ventricular thrombosis;Cardiogenic shock;Cardiolipin antibody positive;Cardiopulmonary failure;Cardio-respiratory arrest;Cardio-respiratory distress;Cardiovascular insufficiency;Carotid arterial embolus;Carotid artery thrombosis;Cataplexy;Catheter site thrombosis;Catheter site vasculitis;Cavernous sinus thrombosis;CDKL5 deficiency disorder;CEC syndrome;Cement embolism;Central nervous system lupus;Central nervous system vasculitis;Cerebellar artery thrombosis;Cerebellar embolism;Cerebral amyloid angiopathy;Cerebral arteritis;Cerebral artery embolism;Cerebral artery thrombosis;Cerebral gas embolism;Cerebral microembolism;Cerebral septic infarct;Cerebral thrombosis;Cerebral venous sinus thrombosis;Cerebral venous thrombosis;Cerebrospinal thrombotic

tamponade;Cerebrovascular accident;Change in seizure presentation;Chest discomfort;ChildPugh-Turcotte score abnormal;Child-Pugh-Turcotte score increased;Chillblains;Choking;Choking sensation;Cholangitis sclerosing;Chronic autoimmune glomerulonephritis;Chronic cutaneous lupus erythematosus;Chronic fatigue syndrome;Chronic gastritis;Chronic inflammatory demyelinating polyradiculoneuropathy;Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids;Chronic recurrent multifocal osteomyelitis;Chronic respiratory failure;Chronic spontaneous urticaria;Circulatory collapse;Circumoral oedema;Circumoral swelling;Clinically isolated syndrome;Clonic convulsion;Coeliac disease;Cogan's syndrome;Cold agglutinins positive;Cold type haemolytic anaemia;Colitis;Colitis erosive;Colitis herpes;Colitis microscopic;Colitis ulcerative;Collagen disorder;Collagen-vascular disease;Complement factor abnormal;Complement factor C1 decreased;Complement factor C2 decreased;Complement factor C3 decreased;Complement factor C4 decreased;Complement factor decreased;Computerised tomogram liver abnormal;Concentric sclerosis;Congenital anomaly;Congenital bilateral perisylvian syndrome;Congenital herpes simplex infection;Congenital myasthenic syndrome;Congenital varicella infection;Congestive hepatopathy;Convulsion in childhood;Convulsions local;Convulsive threshold lowered;Coombs positive haemolytic anaemia;Coronary artery disease;Coronary artery embolism;Coronary artery thrombosis;Coronary bypass thrombosis;Coronavirus infection;Coronavirus test;Coronavirus test negative;Coronavirus test positive;Corpus callosotomy;Cough;Cough variant asthma;COVID-19;COVID-19 immunisation;COVID-19 pneumonia;COVID-19 prophylaxis;COVID-19 treatment;Cranial nerve disorder;Cranial nerve palsies multiple;Cranial nerve paralysis;CREST syndrome;Crohn's disease;Cryofibrinogenaemia;Cryoglobulinaemia;CSF oligoclonal band present;CSWS syndrome;Cutaneous amyloidosis;Cutaneous lupus erythematosus;Cutaneous sarcoidosis;Cutaneous vasculitis;Cyanosis;Cyclic neutropenia;Cystitis interstitial;Cytokine release syndrome;Cytokine storm;De novo purine synthesis inhibitors associated acute inflammatory syndrome;Death neonatal;Deep vein thrombosis;Deep vein thrombosis postoperative;Deficiency of bile secretion;Deja vu;Demyelinating polyneuropathy;Demyelination;Dermatitis;Dermatitis bullous;Dermatitis herpetiformis;Dermatomyositis;Device embolisation;Device related thrombosis;Diabetes mellitus;Diabetic ketoacidosis;Diabetic mastopathy;Dialysis amyloidosis;Dialysis membrane reaction;Diastolic hypotension;Diffuse vasculitis;Digital pitting scar;Disseminated intravascular coagulation;Disseminated intravascular coagulation in newborn;Disseminated neonatal herpes simplex;Disseminated varicella;Disseminated varicella zoster vaccine virus infection;Disseminated varicella zoster virus infection;DNA antibody positive;Double cortex syndrome;Double stranded DNA antibody positive;Dreamy state;Dressler's syndrome;Drop attacks;Drug withdrawal convulsions;Dyspnoea;Early infantile epileptic encephalopathy with burst-suppression;Eclampsia;Eczema herpeticum;Embolia cutis medicamentosa;Embolic cerebellar infarction;Embolic cerebral infarction;Embolic pneumonia;Embolic stroke;Embolism;Embolism arterial;Embolism venous;Encephalitis;Encephalitis allergic;Encephalitis autoimmune;Encephalitis brain stem;Encephalitis haemorrhagic;Encephalitis periaxialis diffusa;Encephalitis post immunisation;Encephalomyelitis;Encephalopathy;Endocrine disorder;Endocrine ophthalmopathy;Endotracheal intubation;Enteritis;Enteritis leukopenic;Enterobacter pneumonia;Enterocolitis;Enteropathic spondylitis;Eosinopenia;Eosinophilic

fasciitis;Eosinophilic granulomatosis with polyangiitis;Eosinophilic oesophagitis;Epidermolysis;Epilepsy;Epilepsy surgery;Epilepsy with myoclonic-atonic seizures;Epileptic aura;Epileptic psychosis;Erythema;Erythema induratum;Erythema multiforme;Erythema nodosum;Evans syndrome;Exanthema subitum;Expanded disability status scale score decreased;Expanded disability status scale score increased;Exposure to communicable disease;Exposure to SARS-CoV-2;Eye oedema;Eye pruritus;Eye swelling;Eyelid oedema;Face oedema;Facial paralysis;Facial paresis;Faciobrachial dystonic seizure;Fat embolism;Febrile convulsion;Febrile infection-related epilepsy syndrome;Febrile neutropenia;Felty's syndrome;Femoral artery embolism;Fibrillary glomerulonephritis;Fibromyalgia;Flushing;Foaming at mouth;Focal cortical resection;Focal dyscognitive seizures;Foetal distress syndrome;Foetal placental thrombosis;Foetor hepaticus;Foreign body embolism;Frontal lobe epilepsy;Fulminant type 1 diabetes mellitus;Galactose elimination capacity test abnormal;Galactose elimination capacity test decreased;Gamma-glutamyltransferase abnormal;Gamma-glutamyltransferase increased;Gastritis herpes;Gastrointestinal amyloidosis;Gelastic seizure;Generalised onset non-motor seizure;Generalised tonic-clonic seizure;Genital herpes;Genital herpes simplex;Genital herpes zoster;Giant cell arteritis;Glomerulonephritis;Glomerulonephritis membranoproliferative;Glomerulonephritis membranous;Glomerulonephritis rapidly progressive;Glossopharyngeal nerve paralysis;Glucose transporter type 1 deficiency syndrome;Glutamate dehydrogenase increased;Glycocholic acid increased;GM2 gangliosidosis;Goodpasture's syndrome;Graft thrombosis;Granulocytopenia;Granulocytopenia neonatal;Granulomatosis with polyangiitis;Granulomatous dermatitis;Grey matter heterotopia;Guanase increased;GuillainBarre syndrome;Haemolytic anaemia;Haemophagocytic lymphohistiocytosis;Haemorrhage;Haemorrhagic ascites;Haemorrhagic disorder;Haemorrhagic pneumonia;Haemorrhagic varicella syndrome;Haemorrhagic vasculitis;Hantavirus pulmonary infection;Hashimoto's encephalopathy;Hashitoxicosis;Hemimegalencephaly;Henoch-Schonlein purpura;HenochSchonlein purpura nephritis;Hepaplastin abnormal;Hepaplastin decreased;Heparin-induced thrombocytopenia;Hepatic amyloidosis;Hepatic artery embolism;Hepatic artery flow decreased;Hepatic artery thrombosis;Hepatic enzyme abnormal;Hepatic enzyme decreased;Hepatic enzyme increased;Hepatic fibrosis marker abnormal;Hepatic fibrosis marker increased;Hepatic function abnormal;Hepatic hydrothorax;Hepatic hypertrophy;Hepatic hypoperfusion;Hepatic lymphocytic infiltration;Hepatic mass;Hepatic pain;Hepatic sequestration;Hepatic vascular resistance increased;Hepatic vascular thrombosis;Hepatic vein embolism;Hepatic vein thrombosis;Hepatic venous pressure gradient abnormal;Hepatic venous pressure gradient increased;Hepatitis;Hepatobiliary scan abnormal;Hepatomegaly;Hepatosplenomegaly;Hereditary angioedema with C1 esterase inhibitor deficiency;Herpes dermatitis;Herpes gestationis;Herpes oesophagitis;Herpes ophthalmic;Herpes pharyngitis;Herpes sepsis;Herpes simplex;Herpes simplex cervicitis;Herpes simplex colitis;Herpes simplex encephalitis;Herpes simplex gastritis;Herpes simplex hepatitis;Herpes simplex meningitis;Herpes simplex meningoencephalitis;Herpes simplex meningomyelitis;Herpes simplex necrotising retinopathy;Herpes simplex oesophagitis;Herpes simplex otitis externa;Herpes simplex pharyngitis;Herpes simplex pneumonia;Herpes simplex reactivation;Herpes simplex sepsis;Herpes simplex viraemia;Herpes simplex virus conjunctivitis neonatal;Herpes simplex visceral;Herpes virus

infection;Herpes zoster;Herpes zoster cutaneous disseminated;Herpes zoster infection neurological;Herpes zoster meningitis;Herpes zoster meningoencephalitis;Herpes zoster meningomyelitis;Herpes zoster meningoradiculitis;Herpes zoster necrotising retinopathy;Herpes zoster oticus;Herpes zoster pharyngitis;Herpes zoster reactivation;Herpetic radiculopathy;Histone antibody positive;Hoigne's syndrome;Human herpesvirus 6 encephalitis;Human herpesvirus 6 infection;Human herpesvirus 6 infection reactivation;Human herpesvirus 7 infection;Human herpesvirus 8 infection;Hyperammonaemia;Hyperbilirubinaemia;Hypercholia;Hypergammaglobulinaemia benign monoclonal;Hyperglycaemic seizure;Hypersensitivity;Hypersensitivity vasculitis;Hyperthyroidism;Hypertransaminasaemia;Hyperventilation;Hypoalbuminaemia;H ypocalcaemic seizure;Hypogammaglobulinaemia;Hypoglossal nerve paralysis;Hypoglossal nerve paresis;Hypoglycaemic seizure;Hyponatraemic seizure;Hypotension;Hypotensive crisis;Hypothenar hammer syndrome;Hypothyroidism;Hypoxia;Idiopathic CD4 lymphocytopenia;Idiopathic generalised epilepsy;Idiopathic interstitial pneumonia;Idiopathic neutropenia;Idiopathic pulmonary fibrosis;IgA nephropathy;IgM nephropathy;IIIrd nerve paralysis;IIIrd nerve paresis;Iliac artery embolism;Immune thrombocytopenia;Immunemediated adverse reaction;Immune-mediated cholangitis;Immune-mediated cholestasis;Immune-mediated cytopenia;Immune-mediated encephalitis;Immune-mediated encephalopathy;Immune-mediated endocrinopathy;Immune-mediated enterocolitis;Immunemediated gastritis;Immune-mediated hepatic disorder;Immune-mediated hepatitis;Immunemediated hyperthyroidism;Immune-mediated hypothyroidism;Immune-mediated myocarditis;Immune-mediated myositis;Immune-mediated nephritis;Immune-mediated neuropathy;Immune-mediated pancreatitis;Immune-mediated pneumonitis;Immune-mediated renal disorder;Immune-mediated thyroiditis;Immune-mediated uveitis;Immunoglobulin G4 related disease;Immunoglobulins abnormal;Implant site thrombosis;Inclusion body myositis;Infantile genetic agranulocytosis;Infantile spasms;Infected vasculitis;Infective thrombosis;Inflammation;Inflammatory bowel disease;Infusion site thrombosis;Infusion site vasculitis;Injection site thrombosis;Injection site urticaria;Injection site vasculitis;Instillation site thrombosis;Insulin autoimmune syndrome;Interstitial granulomatous dermatitis;Interstitial lung disease;Intracardiac mass;Intracardiac thrombus;Intracranial pressure increased;Intrapericardial thrombosis;Intrinsic factor antibody abnormal;Intrinsic factor antibody positive;IPEX syndrome;Irregular breathing;IRVAN syndrome;IVth nerve paralysis;IVth nerve paresis;JC polyomavirus test positive;JC virus CSF test positive;Jeavons syndrome;Jugular vein embolism;Jugular vein thrombosis;Juvenile idiopathic arthritis;Juvenile myoclonic epilepsy;Juvenile polymyositis;Juvenile psoriatic arthritis;Juvenile spondyloarthritis;Kaposi sarcoma inflammatory cytokine syndrome;Kawasaki's disease;Kayser-Fleischer ring;Keratoderma blenorrhagica;Ketosisprone diabetes mellitus;Kounis syndrome;Lafora's myoclonic epilepsy;Lambl's excrescences;Laryngeal dyspnoea;Laryngeal oedema;Laryngeal rheumatoid arthritis;Laryngospasm;Laryngotracheal oedema;Latent autoimmune diabetes in adults;LE cells present;Lemierre syndrome;Lennox-Gastaut syndrome;Leucine aminopeptidase increased;Leukoencephalomyelitis;Leukoencephalopathy;Leukopenia;Leukopenia neonatal;Lewis-Sumner syndrome;Lhermitte's sign;Lichen planopilaris;Lichen planus;Lichen sclerosus;Limbic encephalitis;Linear IgA disease;Lip oedema;Lip swelling;Liver function test abnormal;Liver function test decreased;Liver function test increased;Liver induration;Liver injury;Liver iron concentration abnormal;Liver iron concentration

increased;Liver opacity;Liver palpable;Liver sarcoidosis;Liver scan abnormal;Liver tenderness;Low birth weight baby;Lower respiratory tract herpes infection;Lower respiratory tract infection;Lower respiratory tract infection viral;Lung abscess;Lupoid hepatic cirrhosis;Lupus cystitis;Lupus encephalitis;Lupus endocarditis;Lupus enteritis;Lupus hepatitis;Lupus myocarditis;Lupus myositis;Lupus nephritis;Lupus pancreatitis;Lupus pleurisy;Lupus pneumonitis;Lupus vasculitis;Lupus-like syndrome;Lymphocytic hypophysitis;Lymphocytopenia neonatal;Lymphopenia;MAGIC syndrome;Magnetic resonance imaging liver abnormal;Magnetic resonance proton density fat fraction measurement;Mahler sign;Manufacturing laboratory analytical testing issue;Manufacturing materials issue;Manufacturing production issue;Marburg's variant multiple sclerosis;Marchiafava-Bignami disease;Marine Lenhart syndrome;Mastocytic enterocolitis;Maternal exposure during pregnancy;Medical device site thrombosis;Medical device site vasculitis;MELAS syndrome;Meningitis;Meningitis aseptic;Meningitis herpes;Meningoencephalitis herpes simplex neonatal;Meningoencephalitis herpetic;Meningomyelitis herpes;MERS-CoV test;MERS-CoV test negative;MERS-CoV test positive;Mesangioproliferative glomerulonephritis;Mesenteric artery embolism;Mesenteric artery thrombosis;Mesenteric vein thrombosis;Metapneumovirus infection;Metastatic cutaneous Crohn's disease;Metastatic pulmonary embolism;Microangiopathy;Microembolism;Microscopic polyangiitis;Middle East respiratory syndrome;Migraine-triggered seizure;Miliary pneumonia;Miller Fisher syndrome;Mitochondrial aspartate aminotransferase increased;Mixed connective tissue disease;Model for end stage liver disease score abnormal;Model for end stage liver disease score increased;Molar ratio of total branched-chain amino acid to tyrosine;Molybdenum cofactor deficiency;Monocytopenia;Mononeuritis;Mononeuropathy multiplex;Morphoea;Morvan syndrome;Mouth swelling;Moyamoya disease;Multifocal motor neuropathy;Multiple organ dysfunction syndrome;Multiple sclerosis;Multiple sclerosis relapse;Multiple sclerosis relapse prophylaxis;Multiple subpial transection;Multisystem inflammatory syndrome in children;Muscular sarcoidosis;Myasthenia gravis;Myasthenia gravis crisis;Myasthenia gravis neonatal;Myasthenic syndrome;Myelitis;Myelitis transverse;Myocardial infarction;Myocarditis;Myocarditis post infection;Myoclonic epilepsy;Myoclonic epilepsy and ragged-red fibres;Myokymia;Myositis;Narcolepsy;Nasal herpes;Nasal obstruction;Necrotising herpetic retinopathy;Neonatal Crohn's disease;Neonatal epileptic seizure;Neonatal lupus erythematosus;Neonatal mucocutaneous herpes simplex;Neonatal pneumonia;Neonatal seizure;Nephritis;Nephrogenic systemic fibrosis;Neuralgic amyotrophy;Neuritis;Neuritis cranial;Neuromyelitis optica pseudo relapse;Neuromyelitis optica spectrum disorder;Neuromyotonia;Neuronal neuropathy;Neuropathy peripheral;Neuropathy, ataxia, retinitis pigmentosa syndrome;Neuropsychiatric lupus;Neurosarcoidosis;Neutropenia;Neutropenia neonatal;Neutropenic colitis;Neutropenic infection;Neutropenic sepsis;Nodular rash;Nodular vasculitis;Noninfectious myelitis;Noninfective encephalitis;Noninfective encephalomyelitis;Noninfective oophoritis;Obstetrical pulmonary embolism;Occupational exposure to communicable disease;Occupational exposure to SARS-CoV-2;Ocular hyperaemia;Ocular myasthenia;Ocular pemphigoid;Ocular sarcoidosis;Ocular vasculitis;Oculofacial paralysis;Oedema;Oedema blister;Oedema due to hepatic disease;Oedema mouth;Oesophageal achalasia;Ophthalmic artery thrombosis;Ophthalmic herpes simplex;Ophthalmic herpes zoster;Ophthalmic vein thrombosis;Optic neuritis;Optic

neuropathy;Optic perineuritis;Oral herpes;Oral lichen planus;Oropharyngeal oedema;Oropharyngeal spasm;Oropharyngeal swelling;Osmotic demyelination syndrome;Ovarian vein thrombosis;Overlap syndrome;Paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection;Paget-Schroetter syndrome;Palindromic rheumatism;Palisaded neutrophilic granulomatous dermatitis;Palmoplantar keratoderma;Palpable purpura;Pancreatitis;Panencephalitis;Papillophlebitis;Paracancerous pneumonia;Paradoxical embolism;Parainfluenzae viral laryngotracheobronchitis;Paraneoplastic dermatomyositis;Paraneoplastic pemphigus;Paraneoplastic thrombosis;Paresis cranial nerve;Parietal cell antibody positive;Paroxysmal nocturnal haemoglobinuria;Partial seizures;Partial seizures with secondary generalisation;Patient isolation;Pelvic venous thrombosis;Pemphigoid;Pemphigus;Penile vein thrombosis;Pericarditis;Pericarditis lupus;Perihepatic discomfort;Periorbital oedema;Periorbital swelling;Peripheral artery thrombosis;Peripheral embolism;Peripheral ischaemia;Peripheral vein thrombus extension;Periportal oedema;Peritoneal fluid protein abnormal;Peritoneal fluid protein decreased;Peritoneal fluid protein increased;Peritonitis lupus;Pernicious anaemia;Petit mal epilepsy;Pharyngeal oedema;Pharyngeal swelling;Pityriasis lichenoides et varioliformis acuta;Placenta praevia;Pleuroparenchymal fibroelastosis;Pneumobilia;Pneumonia;Pneumonia adenoviral;Pneumonia cytomegaloviral;Pneumonia herpes viral;Pneumonia influenzal;Pneumonia measles;Pneumonia mycoplasmal;Pneumonia necrotising;Pneumonia parainfluenzae viral;Pneumonia respiratory syncytial viral;Pneumonia viral;POEMS syndrome;Polyarteritis nodosa;Polyarthritis;Polychondritis;Polyglandular autoimmune syndrome type I;Polyglandular autoimmune syndrome type II;Polyglandular autoimmune syndrome type III;Polyglandular disorder;Polymicrogyria;Polymyalgia rheumatica;Polymyositis;Polyneuropathy;Polyneuropathy idiopathic progressive;Portal pyaemia;Portal vein embolism;Portal vein flow decreased;Portal vein pressure increased;Portal vein thrombosis;Portosplenomesenteric venous thrombosis;Post procedural hypotension;Post procedural pneumonia;Post procedural pulmonary embolism;Post stroke epilepsy;Post stroke seizure;Post thrombotic retinopathy;Post thrombotic syndrome;Post viral fatigue syndrome;Postictal headache;Postictal paralysis;Postictal psychosis;Postictal state;Postoperative respiratory distress;Postoperative respiratory failure;Postoperative thrombosis;Postpartum thrombosis;Postpartum venous thrombosis;Postpericardiotomy syndrome;Post-traumatic epilepsy;Postural orthostatic tachycardia syndrome;Precerebral artery thrombosis;Pre-eclampsia;Preictal state;Premature labour;Premature menopause;Primary amyloidosis;Primary biliary cholangitis;Primary progressive multiple sclerosis;Procedural shock;Proctitis herpes;Proctitis ulcerative;Product availability issue;Product distribution issue;Product supply issue;Progressive facial hemiatrophy;Progressive multifocal leukoencephalopathy;Progressive multiple sclerosis;Progressive relapsing multiple sclerosis;Prosthetic cardiac valve thrombosis;Pruritus;Pruritus allergic;Pseudovasculitis;Psoriasis;Psoriatic arthropathy;Pulmonary amyloidosis;Pulmonary artery thrombosis;Pulmonary embolism;Pulmonary fibrosis;Pulmonary haemorrhage;Pulmonary microemboli;Pulmonary oil microembolism;Pulmonary renal syndrome;Pulmonary sarcoidosis;Pulmonary sepsis;Pulmonary thrombosis;Pulmonary tumour thrombotic microangiopathy;Pulmonary vasculitis;Pulmonary veno-occlusive disease;Pulmonary venous thrombosis;Pyoderma gangrenosum;Pyostomatitis vegetans;Pyrexia;Quarantine;Radiation leukopenia;Radiculitis

brachial;Radiologically isolated syndrome;Rash;Rash erythematous;Rash pruritic;Rasmussen encephalitis;Raynaud's phenomenon;Reactive capillary endothelial proliferation;Relapsing multiple sclerosis;Relapsing-remitting multiple sclerosis;Renal amyloidosis;Renal arteritis;Renal artery thrombosis;Renal embolism;Renal failure;Renal vascular thrombosis;Renal vasculitis;Renal vein embolism;Renal vein thrombosis;Respiratory arrest;Respiratory disorder;Respiratory distress;Respiratory failure;Respiratory paralysis;Respiratory syncytial virus bronchiolitis;Respiratory syncytial virus bronchitis;Retinal artery embolism;Retinal artery occlusion;Retinal artery thrombosis;Retinal vascular thrombosis;Retinal vasculitis;Retinal vein occlusion;Retinal vein thrombosis;Retinol binding protein decreased;Retinopathy;Retrograde portal vein flow;Retroperitoneal fibrosis;Reversible airways obstruction;Reynold's syndrome;Rheumatic brain disease;Rheumatic disorder;Rheumatoid arthritis;Rheumatoid factor increased;Rheumatoid factor positive;Rheumatoid factor quantitative increased;Rheumatoid lung;Rheumatoid neutrophilic dermatosis;Rheumatoid nodule;Rheumatoid nodule removal;Rheumatoid scleritis;Rheumatoid vasculitis;Saccadic eye movement;SAPHO syndrome;Sarcoidosis;SARS-CoV-1 test;SARS-CoV-1 test negative;SARS-CoV-1 test positive;SARS-CoV-2 antibody test;SARS-CoV-2 antibody test negative;SARS-CoV-2 antibody test positive;SARS-CoV-2 carrier;SARS-CoV-2 sepsis;SARS-CoV-2 test;SARSCoV-2 test false negative;SARS-CoV-2 test false positive;SARS-CoV-2 test negative;SARSCoV-2 test positive;SARS-CoV-2 viraemia;Satoyoshi syndrome;Schizencephaly;Scleritis;Sclerodactylia;Scleroderma;Scleroderma associated digital ulcer;Scleroderma renal crisis;Scleroderma-like reaction;Secondary amyloidosis;Secondary cerebellar degeneration;Secondary progressive multiple sclerosis;Segmented hyalinising vasculitis;Seizure;Seizure anoxic;Seizure cluster;Seizure like phenomena;Seizure prophylaxis;Sensation of foreign body;Septic embolus;Septic pulmonary embolism;Severe acute respiratory syndrome;Severe myoclonic epilepsy of infancy;Shock;Shock symptom;Shrinking lung syndrome;Shunt thrombosis;Silent thyroiditis;Simple partial seizures;Sjogren's syndrome;Skin swelling;SLE arthritis;Smooth muscle antibody positive;Sneezing;Spinal artery embolism;Spinal artery thrombosis;Splenic artery thrombosis;Splenic embolism;Splenic thrombosis;Splenic vein thrombosis;Spondylitis;Spondyloarthropathy;Spontaneous heparin-induced thrombocytopenia syndrome;Status epilepticus;Stevens-Johnson syndrome;Stiff leg syndrome;Stiff person syndrome;Stillbirth;Still's disease;Stoma site thrombosis;Stoma site vasculitis;Stress cardiomyopathy;Stridor;Subacute cutaneous lupus erythematosus;Subacute endocarditis;Subacute inflammatory demyelinating polyneuropathy;Subclavian artery embolism;Subclavian artery thrombosis;Subclavian vein thrombosis;Sudden unexplained death in epilepsy;Superior sagittal sinus thrombosis;Susac's syndrome;Suspected COVID19;Swelling;Swelling face;Swelling of eyelid;Swollen tongue;Sympathetic ophthalmia;Systemic lupus erythematosus;Systemic lupus erythematosus disease activity index abnormal;Systemic lupus erythematosus disease activity index decreased;Systemic lupus erythematosus disease activity index increased;Systemic lupus erythematosus rash;Systemic scleroderma;Systemic sclerosis pulmonary;Tachycardia;Tachypnoea;Takayasu's arteritis;Temporal lobe epilepsy;Terminal ileitis;Testicular autoimmunity;Throat tightness;Thromboangiitis obliterans;Thrombocytopenia;Thrombocytopenic purpura;Thrombophlebitis;Thrombophlebitis migrans;Thrombophlebitis

neonatal;Thrombophlebitis septic;Thrombophlebitis superficial;Thromboplastin antibody positive;Thrombosis;Thrombosis corpora cavernosa;Thrombosis in device;Thrombosis mesenteric vessel;Thrombotic cerebral infarction;Thrombotic microangiopathy;Thrombotic stroke;Thrombotic thrombocytopenic purpura;Thyroid disorder;Thyroid stimulating immunoglobulin increased;Thyroiditis;Tongue amyloidosis;Tongue biting;Tongue oedema;Tonic clonic movements;Tonic convulsion;Tonic posturing;Topectomy;Total bile acids increased;Toxic epidermal necrolysis;Toxic leukoencephalopathy;Toxic oil syndrome;Tracheal obstruction;Tracheal oedema;Tracheobronchitis;Tracheobronchitis mycoplasmal;Tracheobronchitis viral;Transaminases abnormal;Transaminases increased;Transfusion-related alloimmune neutropenia;Transient epileptic amnesia;Transverse sinus thrombosis;Trigeminal nerve paresis;Trigeminal neuralgia;Trigeminal palsy;Truncus coeliacus thrombosis;Tuberous sclerosis complex;Tubulointerstitial nephritis and uveitis syndrome;Tumefactive multiple sclerosis;Tumour embolism;Tumour thrombosis;Type 1 diabetes mellitus;Type I hypersensitivity;Type III immune complex mediated reaction;Uhthoff's phenomenon;Ulcerative keratitis;Ultrasound liver abnormal;Umbilical cord thrombosis;Uncinate fits;Undifferentiated connective tissue disease;Upper airway obstruction;Urine bilirubin increased;Urobilinogen urine decreased;Urobilinogen urine increased;Urticaria;Urticaria papular;Urticarial vasculitis;Uterine rupture;Uveitis;Vaccination site thrombosis;Vaccination site vasculitis;Vagus nerve paralysis;Varicella;Varicella keratitis;Varicella post vaccine;Varicella zoster gastritis;Varicella zoster oesophagitis;Varicella zoster pneumonia;Varicella zoster sepsis;Varicella zoster virus infection;Vasa praevia;Vascular graft thrombosis;Vascular pseudoaneurysm thrombosis;Vascular purpura;Vascular stent thrombosis;Vasculitic rash;Vasculitic ulcer;Vasculitis;Vasculitis gastrointestinal;Vasculitis necrotising;Vena cava embolism;Vena cava thrombosis;Venous intravasation;Venous recanalisation;Venous thrombosis;Venous thrombosis in pregnancy;Venous thrombosis limb;Venous thrombosis neonatal;Vertebral artery thrombosis;Vessel puncture site thrombosis;Visceral venous thrombosis;VIth nerve paralysis;VIth nerve paresis;Vitiligo;Vocal cord paralysis;Vocal cord paresis;Vogt-Koyanagi-Harada disease;Warm type haemolytic anaemia;Wheezing;White nipple sign;XIth nerve paralysis;X-ray hepatobiliary abnormal;Young's syndrome;Zika virus associated Guillain Barre syndrome.

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In the dunes on Swansea Foreshore.

Not entirely sure how sharp this is because heat and humidity gives the likes of me fuzzy eyes (Uhthoff's Syndrome)

Four banded longhorn beetle . Leptura quadrifasciata formerly Strangalia quadrifasciata.

Leptura quadrifasciata (Linnaeus, 1758)

A very widely distributed albeit very local species occuring throughout mainland UK north to Easter Ross (Twinn and Harding), there are several areas with many post 1970 records; the southeast below the Thames, south Wales, the east midlands around the Humber and north Yorkshire; near coastal around Withy. Stated by Uhthoff-Neufmann (1988) to becoming scarcer. Although we have not recorded the species in our Watford area its presence should not be unexpected as they were common, in some years at least, during the late 1970's and through the 1980's at Harefield place nature reserve near Uxbridge, along the Colne valley to the south of us. The adult beetles fly readily in hot sunshine and visit a range of flowers: we have seen them on various umbels and they are known to frequent angelica, bracken, brambles, hawthorn, hogweed, meadowsweet, ragwort, rubus, spiraea, thistles, valerian and woody nightshade (Uhthoff-Neufmann loc. cit.).

The species is polyphagous with larvae developing in dead or decaying wood, especially lower parts of standing trees, stumps, felled trunks and branches down to 15cm in diameter (Alexander), they inhabit wet or dry wood but dry wood is needed for pupation. Larvae bore meandering galleries in the outer sapwood in May or June (Bily and Mehl). A wide range of hosts has been recorded including alder, aspen, beech, birch (which may be the preferred host), hazel, oak, poplar, sallow, willow, elder and also various conifers eg picea and spruce. The life cycle takes two to three years and infestations often continue for several years. Adults generally occur from June to August but have been recorded as early as March.

11-20mm. Apical antennal segments, four macula on each elytron and, in the female only, anterior tibiae pale, otherwise black. Entire body and appendages clothed with short and dense pubescence; pale over elytral maacula otherwise mostly black. Head obliquely inclined to longitudinal axis of body. Vertex roughly sculptured and depressed medially, surface below antennae, including labrum, densely punctured. Eyes transverse, anterior margin with a deep, curved incision. Temples short and prominent in front of a narrow and prominent neck. Antennae longer in male; reaching to elytral apex, in female to middle of elytra. Second antennal segment short; almost quadrate, remainder elongate. Pronotum slightly transverse; campanulate with sharp, obliquely protruding hind angles. Without lateral sculpture or margins, constricted behind front margin and with a deep transverse furrow in front of bisinuate hind margins. Surface widely depressed either side of middle, with fine and dense puncturation, the pubescence may be testaceous near the basal margin. Elyta around 2.2 times longer than broad at the humerus, surface lustrous with fine puncturation. Apices obliquely truncate or incurved, with an acute tooth at external angle and another weaker tooth at sutural angle. Legs long and robust, femora not, or only weakly, clavate. Tibiae without teeth but with two well developed spurs inside at apex. First metatarsomere as lonf as others combined. Last segment of tarsi long and curved. Claws smooth and with a small basal tooth.

Typical elytral pattern is black with four transverse testaceous macula but these may vary in extent and in extreme cases the elytra are black with a small yellow humeral spot (Bily and Mehl).

Two species may be casually mistaken for quadrifasciata. In Judolia sexmaculata (L.) the elytra are black with three transverse yellow marks and rounded apically. A mostly northern Scottish species.

In L.aurulenta the legs and basal antennal segments are red and the anterior and posterior margins of the pronotum are fringed with yellow pubescence. A rare southern, mostly near coastal, species.

Description from 1 Dyfed specimens at X20 plus additions from Bily and Mehl

Reference

Uhthoff-Kaufmann, R.R. 1988 The Occurence of the genus Strangalia serville in the British Isles. Ent.Rec. 100:63-71.

GST volunteer day at Duck End NR 29th July 2008 TL051374

Michael Geiser1:38am Feb 6 2015

Leptura quadrifasciata

A very widely distributed albeit very local species occuring throughout mainland UK north to Easter Ross (Twinn and Harding), there are several areas with many post 1970 records; the southeast below the Thames, south Wales, the east midlands around the Humber and north Yorkshire; near coastal around Withy. Stated by Uhthoff-Neufmann (1988) to becoming scarcer. Although we have not recorded the species in our Watford area its presence should not be unexpected as they were common, in some years at least, during the late 1970's and through the 1980's at Harefield place nature reserve near Uxbridge, along the Colne valley to the south of us. The adult beetles fly readily in hot sunshine and visit a range of flowers: we have seen them on various umbels and they are known to frequent angelica, bracken, brambles, hawthorn, hogweed, meadowsweet, ragwort, rubus, spiraea, thistles, valerian and woody nightshade (Uhthoff-Neufmann loc. cit.).

The species is polyphagous with larvae developing in dead or decaying wood, especially lower parts of standing trees, stumps, felled trunks and branches down to 15cm in diameter (Alexander), they inhabit wet or dry wood but dry wood is needed for pupation. Larvae bore meandering galleries in the outer sapwood in May or June (Bily and Mehl). A wide range of hosts has been recorded including alder, aspen, beech, birch (which may be the preferred host), hazel, oak, poplar, sallow, willow, elder and also various conifers eg picea and spruce. The life cycle takes two to three years and infestations often continue for several years. Adults generally occur from June to August but have been recorded as early as March.

11-20mm. Apical antennal segments, four macula on each elytron and, in the female only, anterior tibiae pale, otherwise black. Entire body and appendages clothed with short and dense pubescence; pale over elytral maacula otherwise mostly black. Head obliquely inclined to longitudinal axis of body. Vertex roughly sculptured and depressed medially, surface below antennae, including labrum, densely punctured. Eyes transverse, anterior margin with a deep, curved incision. Temples short and prominent in front of a narrow and prominent neck. Antennae longer in male; reaching to elytral apex, in female to middle of elytra. Second antennal segment short; almost quadrate, remainder elongate. Pronotum slightly transverse; campanulate with sharp, obliquely protruding hind angles. Without lateral sculpture or margins, constricted behind front margin and with a deep transverse furrow in front of bisinuate hind margins. Surface widely depressed either side of middle, with fine and dense puncturation, the pubescence may be testaceous near the basal margin. Elyta around 2.2 times longer than broad at the humerus, surface lustrous with fine puncturation. Apices obliquely truncate or incurved, with an acute tooth at external angle and another weaker tooth at sutural angle. Legs long and robust, femora not, or only weakly, clavate. Tibiae without teeth but with two well developed spurs inside at apex. First metatarsomere as lonf as others combined. Last segment of tarsi long and curved. Claws smooth and with a small basal tooth.

Typical elytral pattern is black with four transverse testaceous macula but these may vary in extent and in extreme cases the elytra are black with a small yellow humeral spot (Bily and Mehl).

Two species may be casually mistaken for quadrifasciata. In Judolia sexmaculata (L.) the elytra are black with three transverse yellow marks and rounded apically. A mostly northern Scottish species.

In L.aurulenta the legs and basal antennal segments are red and the anterior and posterior margins of the pronotum are fringed with yellow pubescence. A rare southern, mostly near coastal, species.

Description from 1 Dyfed specimens at X20 plus additions from Bily and Mehl

Reference

Uhthoff-Kaufmann, R.R. 1988 The Occurence of the genus Strangalia serville in the British Isles. Ent.Rec. 100:63-71.

That must have been an easy job, but a long day. Out of Mac' Yard before 5 am, up the Newmarket Sub., setting off cars at Barrie, for road switchers to Alliston, Collingwood and Orillia customers. From there 718 would head up to Orillia and turn on to the Midland Sub. setting off most of its cars, empty hoppers at Uhthoff stone quarry, then on to Midland with its remaining grain cars.

I worked at Uhthoff servicing the cars, usually set off before I arrived a 7. Often times after work I'd be off on the motorcycle, perhaps to Midland where I'd see the units and van idling away down by the station.

At the ends of the shifts of the Elevators there'd be loaded cars to pick up, and all along the route back to Toronto.

I can remember sitting in the Car Dept. office at the Barrie (Allandale) Yards, the windows were rattling as the southbound freight approached downtown Barrie, across Kempenfelt Bay. 719 usually arrived after the commuter train was put into layover.

From the station and the yard tracks there is a slight incline to the south. After picking up the Barrie cars it was interesting to see how well a hogger could handle his train.

Here's something you'll never see again, after work at the Uhthoff quarry on June 3, 1988, I paused to get this shot of southbound 719 at Burnside Line, near Orillia.

Page Thirty-six.

Building Committee, Architect, Quantity Surveyor, General Contractors, Sub Contractors, Carving, Clerk of the Works, Manager, Formen.

Official Opening of the new buildings by His Grace the Archbishop of York, June 22nd, 1935.

Four banded longhorn beetle . Leptura quadrifasciata formerly Strangalia quadrifasciata.

Leptura quadrifasciata (Linnaeus, 1758)

A very widely distributed albeit very local species occuring throughout mainland UK north to Easter Ross (Twinn and Harding), there are several areas with many post 1970 records; the southeast below the Thames, south Wales, the east midlands around the Humber and north Yorkshire; near coastal around Withy. Stated by Uhthoff-Neufmann (1988) to becoming scarcer. Although we have not recorded the species in our Watford area its presence should not be unexpected as they were common, in some years at least, during the late 1970's and through the 1980's at Harefield place nature reserve near Uxbridge, along the Colne valley to the south of us. The adult beetles fly readily in hot sunshine and visit a range of flowers: we have seen them on various umbels and they are known to frequent angelica, bracken, brambles, hawthorn, hogweed, meadowsweet, ragwort, rubus, spiraea, thistles, valerian and woody nightshade (Uhthoff-Neufmann loc. cit.).

The species is polyphagous with larvae developing in dead or decaying wood, especially lower parts of standing trees, stumps, felled trunks and branches down to 15cm in diameter (Alexander), they inhabit wet or dry wood but dry wood is needed for pupation. Larvae bore meandering galleries in the outer sapwood in May or June (Bily and Mehl). A wide range of hosts has been recorded including alder, aspen, beech, birch (which may be the preferred host), hazel, oak, poplar, sallow, willow, elder and also various conifers eg picea and spruce. The life cycle takes two to three years and infestations often continue for several years. Adults generally occur from June to August but have been recorded as early as March.

11-20mm. Apical antennal segments, four macula on each elytron and, in the female only, anterior tibiae pale, otherwise black. Entire body and appendages clothed with short and dense pubescence; pale over elytral maacula otherwise mostly black. Head obliquely inclined to longitudinal axis of body. Vertex roughly sculptured and depressed medially, surface below antennae, including labrum, densely punctured. Eyes transverse, anterior margin with a deep, curved incision. Temples short and prominent in front of a narrow and prominent neck. Antennae longer in male; reaching to elytral apex, in female to middle of elytra. Second antennal segment short; almost quadrate, remainder elongate. Pronotum slightly transverse; campanulate with sharp, obliquely protruding hind angles. Without lateral sculpture or margins, constricted behind front margin and with a deep transverse furrow in front of bisinuate hind margins. Surface widely depressed either side of middle, with fine and dense puncturation, the pubescence may be testaceous near the basal margin. Elyta around 2.2 times longer than broad at the humerus, surface lustrous with fine puncturation. Apices obliquely truncate or incurved, with an acute tooth at external angle and another weaker tooth at sutural angle. Legs long and robust, femora not, or only weakly, clavate. Tibiae without teeth but with two well developed spurs inside at apex. First metatarsomere as lonf as others combined. Last segment of tarsi long and curved. Claws smooth and with a small basal tooth.

Typical elytral pattern is black with four transverse testaceous macula but these may vary in extent and in extreme cases the elytra are black with a small yellow humeral spot (Bily and Mehl).

Two species may be casually mistaken for quadrifasciata. In Judolia sexmaculata (L.) the elytra are black with three transverse yellow marks and rounded apically. A mostly northern Scottish species.

In L.aurulenta the legs and basal antennal segments are red and the anterior and posterior margins of the pronotum are fringed with yellow pubescence. A rare southern, mostly near coastal, species.

Description from 1 Dyfed specimens at X20 plus additions from Bily and Mehl

Reference

Uhthoff-Kaufmann, R.R. 1988 The Occurence of the genus Strangalia serville in the British Isles. Ent.Rec. 100:63-71.

Four banded longhorn beetle . Leptura quadrifasciata formerly Strangalia quadrifasciata.

Leptura quadrifasciata (Linnaeus, 1758)

A very widely distributed albeit very local species occuring throughout mainland UK north to Easter Ross (Twinn and Harding), there are several areas with many post 1970 records; the southeast below the Thames, south Wales, the east midlands around the Humber and north Yorkshire; near coastal around Withy. Stated by Uhthoff-Neufmann (1988) to becoming scarcer. Although we have not recorded the species in our Watford area its presence should not be unexpected as they were common, in some years at least, during the late 1970's and through the 1980's at Harefield place nature reserve near Uxbridge, along the Colne valley to the south of us. The adult beetles fly readily in hot sunshine and visit a range of flowers: we have seen them on various umbels and they are known to frequent angelica, bracken, brambles, hawthorn, hogweed, meadowsweet, ragwort, rubus, spiraea, thistles, valerian and woody nightshade (Uhthoff-Neufmann loc. cit.).

The species is polyphagous with larvae developing in dead or decaying wood, especially lower parts of standing trees, stumps, felled trunks and branches down to 15cm in diameter (Alexander), they inhabit wet or dry wood but dry wood is needed for pupation. Larvae bore meandering galleries in the outer sapwood in May or June (Bily and Mehl). A wide range of hosts has been recorded including alder, aspen, beech, birch (which may be the preferred host), hazel, oak, poplar, sallow, willow, elder and also various conifers eg picea and spruce. The life cycle takes two to three years and infestations often continue for several years. Adults generally occur from June to August but have been recorded as early as March.

11-20mm. Apical antennal segments, four macula on each elytron and, in the female only, anterior tibiae pale, otherwise black. Entire body and appendages clothed with short and dense pubescence; pale over elytral maacula otherwise mostly black. Head obliquely inclined to longitudinal axis of body. Vertex roughly sculptured and depressed medially, surface below antennae, including labrum, densely punctured. Eyes transverse, anterior margin with a deep, curved incision. Temples short and prominent in front of a narrow and prominent neck. Antennae longer in male; reaching to elytral apex, in female to middle of elytra. Second antennal segment short; almost quadrate, remainder elongate. Pronotum slightly transverse; campanulate with sharp, obliquely protruding hind angles. Without lateral sculpture or margins, constricted behind front margin and with a deep transverse furrow in front of bisinuate hind margins. Surface widely depressed either side of middle, with fine and dense puncturation, the pubescence may be testaceous near the basal margin. Elyta around 2.2 times longer than broad at the humerus, surface lustrous with fine puncturation. Apices obliquely truncate or incurved, with an acute tooth at external angle and another weaker tooth at sutural angle. Legs long and robust, femora not, or only weakly, clavate. Tibiae without teeth but with two well developed spurs inside at apex. First metatarsomere as lonf as others combined. Last segment of tarsi long and curved. Claws smooth and with a small basal tooth.

Typical elytral pattern is black with four transverse testaceous macula but these may vary in extent and in extreme cases the elytra are black with a small yellow humeral spot (Bily and Mehl).

Two species may be casually mistaken for quadrifasciata. In Judolia sexmaculata (L.) the elytra are black with three transverse yellow marks and rounded apically. A mostly northern Scottish species.

In L.aurulenta the legs and basal antennal segments are red and the anterior and posterior margins of the pronotum are fringed with yellow pubescence. A rare southern, mostly near coastal, species.

Description from 1 Dyfed specimens at X20 plus additions from Bily and Mehl

Reference

Uhthoff-Kaufmann, R.R. 1988 The Occurence of the genus Strangalia serville in the British Isles. Ent.Rec. 100:63-71.

Severn Township, northwest of Orillia. The former CN and CP lines between Midland/Port McNicoll and Orillia are visible

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m2crowd blog: m2crowd.blogspot.com/

m2crowd blog: m2crowd.wordpress.com/

m2crowd google: m2crowd-estafa-fraude.negocio.site

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Crosses Uhthoff Rail Trail, formerly CP Port McNicoll Subdivision

Four banded longhorn beetle . Leptura quadrifasciata formerly Strangalia quadrifasciata.

Leptura quadrifasciata (Linnaeus, 1758)

A very widely distributed albeit very local species occuring throughout mainland UK north to Easter Ross (Twinn and Harding), there are several areas with many post 1970 records; the southeast below the Thames, south Wales, the east midlands around the Humber and north Yorkshire; near coastal around Withy. Stated by Uhthoff-Neufmann (1988) to becoming scarcer. Although we have not recorded the species in our Watford area its presence should not be unexpected as they were common, in some years at least, during the late 1970's and through the 1980's at Harefield place nature reserve near Uxbridge, along the Colne valley to the south of us. The adult beetles fly readily in hot sunshine and visit a range of flowers: we have seen them on various umbels and they are known to frequent angelica, bracken, brambles, hawthorn, hogweed, meadowsweet, ragwort, rubus, spiraea, thistles, valerian and woody nightshade (Uhthoff-Neufmann loc. cit.).

The species is polyphagous with larvae developing in dead or decaying wood, especially lower parts of standing trees, stumps, felled trunks and branches down to 15cm in diameter (Alexander), they inhabit wet or dry wood but dry wood is needed for pupation. Larvae bore meandering galleries in the outer sapwood in May or June (Bily and Mehl). A wide range of hosts has been recorded including alder, aspen, beech, birch (which may be the preferred host), hazel, oak, poplar, sallow, willow, elder and also various conifers eg picea and spruce. The life cycle takes two to three years and infestations often continue for several years. Adults generally occur from June to August but have been recorded as early as March.

11-20mm. Apical antennal segments, four macula on each elytron and, in the female only, anterior tibiae pale, otherwise black. Entire body and appendages clothed with short and dense pubescence; pale over elytral maacula otherwise mostly black. Head obliquely inclined to longitudinal axis of body. Vertex roughly sculptured and depressed medially, surface below antennae, including labrum, densely punctured. Eyes transverse, anterior margin with a deep, curved incision. Temples short and prominent in front of a narrow and prominent neck. Antennae longer in male; reaching to elytral apex, in female to middle of elytra. Second antennal segment short; almost quadrate, remainder elongate. Pronotum slightly transverse; campanulate with sharp, obliquely protruding hind angles. Without lateral sculpture or margins, constricted behind front margin and with a deep transverse furrow in front of bisinuate hind margins. Surface widely depressed either side of middle, with fine and dense puncturation, the pubescence may be testaceous near the basal margin. Elyta around 2.2 times longer than broad at the humerus, surface lustrous with fine puncturation. Apices obliquely truncate or incurved, with an acute tooth at external angle and another weaker tooth at sutural angle. Legs long and robust, femora not, or only weakly, clavate. Tibiae without teeth but with two well developed spurs inside at apex. First metatarsomere as lonf as others combined. Last segment of tarsi long and curved. Claws smooth and with a small basal tooth.

Typical elytral pattern is black with four transverse testaceous macula but these may vary in extent and in extreme cases the elytra are black with a small yellow humeral spot (Bily and Mehl).

Two species may be casually mistaken for quadrifasciata. In Judolia sexmaculata (L.) the elytra are black with three transverse yellow marks and rounded apically. A mostly northern Scottish species.

In L.aurulenta the legs and basal antennal segments are red and the anterior and posterior margins of the pronotum are fringed with yellow pubescence. A rare southern, mostly near coastal, species.

Description from 1 Dyfed specimens at X20 plus additions from Bily and Mehl

Reference

Uhthoff-Kaufmann, R.R. 1988 The Occurence of the genus Strangalia serville in the British Isles. Ent.Rec. 100:63-71.

Four banded longhorn beetle . Leptura quadrifasciata formerly Strangalia quadrifasciata.

Leptura quadrifasciata (Linnaeus, 1758)

A very widely distributed albeit very local species occuring throughout mainland UK north to Easter Ross (Twinn and Harding), there are several areas with many post 1970 records; the southeast below the Thames, south Wales, the east midlands around the Humber and north Yorkshire; near coastal around Withy. Stated by Uhthoff-Neufmann (1988) to becoming scarcer. Although we have not recorded the species in our Watford area its presence should not be unexpected as they were common, in some years at least, during the late 1970's and through the 1980's at Harefield place nature reserve near Uxbridge, along the Colne valley to the south of us. The adult beetles fly readily in hot sunshine and visit a range of flowers: we have seen them on various umbels and they are known to frequent angelica, bracken, brambles, hawthorn, hogweed, meadowsweet, ragwort, rubus, spiraea, thistles, valerian and woody nightshade (Uhthoff-Neufmann loc. cit.).

The species is polyphagous with larvae developing in dead or decaying wood, especially lower parts of standing trees, stumps, felled trunks and branches down to 15cm in diameter (Alexander), they inhabit wet or dry wood but dry wood is needed for pupation. Larvae bore meandering galleries in the outer sapwood in May or June (Bily and Mehl). A wide range of hosts has been recorded including alder, aspen, beech, birch (which may be the preferred host), hazel, oak, poplar, sallow, willow, elder and also various conifers eg picea and spruce. The life cycle takes two to three years and infestations often continue for several years. Adults generally occur from June to August but have been recorded as early as March.

11-20mm. Apical antennal segments, four macula on each elytron and, in the female only, anterior tibiae pale, otherwise black. Entire body and appendages clothed with short and dense pubescence; pale over elytral maacula otherwise mostly black. Head obliquely inclined to longitudinal axis of body. Vertex roughly sculptured and depressed medially, surface below antennae, including labrum, densely punctured. Eyes transverse, anterior margin with a deep, curved incision. Temples short and prominent in front of a narrow and prominent neck. Antennae longer in male; reaching to elytral apex, in female to middle of elytra. Second antennal segment short; almost quadrate, remainder elongate. Pronotum slightly transverse; campanulate with sharp, obliquely protruding hind angles. Without lateral sculpture or margins, constricted behind front margin and with a deep transverse furrow in front of bisinuate hind margins. Surface widely depressed either side of middle, with fine and dense puncturation, the pubescence may be testaceous near the basal margin. Elyta around 2.2 times longer than broad at the humerus, surface lustrous with fine puncturation. Apices obliquely truncate or incurved, with an acute tooth at external angle and another weaker tooth at sutural angle. Legs long and robust, femora not, or only weakly, clavate. Tibiae without teeth but with two well developed spurs inside at apex. First metatarsomere as lonf as others combined. Last segment of tarsi long and curved. Claws smooth and with a small basal tooth.

Typical elytral pattern is black with four transverse testaceous macula but these may vary in extent and in extreme cases the elytra are black with a small yellow humeral spot (Bily and Mehl).

Two species may be casually mistaken for quadrifasciata. In Judolia sexmaculata (L.) the elytra are black with three transverse yellow marks and rounded apically. A mostly northern Scottish species.

In L.aurulenta the legs and basal antennal segments are red and the anterior and posterior margins of the pronotum are fringed with yellow pubescence. A rare southern, mostly near coastal, species.

Description from 1 Dyfed specimens at X20 plus additions from Bily and Mehl

Reference

Uhthoff-Kaufmann, R.R. 1988 The Occurence of the genus Strangalia serville in the British Isles. Ent.Rec. 100:63-71.

Four banded longhorn beetle . Leptura quadrifasciata formerly Strangalia quadrifasciata.

Leptura quadrifasciata (Linnaeus, 1758)

A very widely distributed albeit very local species occuring throughout mainland UK north to Easter Ross (Twinn and Harding), there are several areas with many post 1970 records; the southeast below the Thames, south Wales, the east midlands around the Humber and north Yorkshire; near coastal around Withy. Stated by Uhthoff-Neufmann (1988) to becoming scarcer. Although we have not recorded the species in our Watford area its presence should not be unexpected as they were common, in some years at least, during the late 1970's and through the 1980's at Harefield place nature reserve near Uxbridge, along the Colne valley to the south of us. The adult beetles fly readily in hot sunshine and visit a range of flowers: we have seen them on various umbels and they are known to frequent angelica, bracken, brambles, hawthorn, hogweed, meadowsweet, ragwort, rubus, spiraea, thistles, valerian and woody nightshade (Uhthoff-Neufmann loc. cit.).

The species is polyphagous with larvae developing in dead or decaying wood, especially lower parts of standing trees, stumps, felled trunks and branches down to 15cm in diameter (Alexander), they inhabit wet or dry wood but dry wood is needed for pupation. Larvae bore meandering galleries in the outer sapwood in May or June (Bily and Mehl). A wide range of hosts has been recorded including alder, aspen, beech, birch (which may be the preferred host), hazel, oak, poplar, sallow, willow, elder and also various conifers eg picea and spruce. The life cycle takes two to three years and infestations often continue for several years. Adults generally occur from June to August but have been recorded as early as March.

11-20mm. Apical antennal segments, four macula on each elytron and, in the female only, anterior tibiae pale, otherwise black. Entire body and appendages clothed with short and dense pubescence; pale over elytral maacula otherwise mostly black. Head obliquely inclined to longitudinal axis of body. Vertex roughly sculptured and depressed medially, surface below antennae, including labrum, densely punctured. Eyes transverse, anterior margin with a deep, curved incision. Temples short and prominent in front of a narrow and prominent neck. Antennae longer in male; reaching to elytral apex, in female to middle of elytra. Second antennal segment short; almost quadrate, remainder elongate. Pronotum slightly transverse; campanulate with sharp, obliquely protruding hind angles. Without lateral sculpture or margins, constricted behind front margin and with a deep transverse furrow in front of bisinuate hind margins. Surface widely depressed either side of middle, with fine and dense puncturation, the pubescence may be testaceous near the basal margin. Elyta around 2.2 times longer than broad at the humerus, surface lustrous with fine puncturation. Apices obliquely truncate or incurved, with an acute tooth at external angle and another weaker tooth at sutural angle. Legs long and robust, femora not, or only weakly, clavate. Tibiae without teeth but with two well developed spurs inside at apex. First metatarsomere as lonf as others combined. Last segment of tarsi long and curved. Claws smooth and with a small basal tooth.

Typical elytral pattern is black with four transverse testaceous macula but these may vary in extent and in extreme cases the elytra are black with a small yellow humeral spot (Bily and Mehl).

Two species may be casually mistaken for quadrifasciata. In Judolia sexmaculata (L.) the elytra are black with three transverse yellow marks and rounded apically. A mostly northern Scottish species.

In L.aurulenta the legs and basal antennal segments are red and the anterior and posterior margins of the pronotum are fringed with yellow pubescence. A rare southern, mostly near coastal, species.

Description from 1 Dyfed specimens at X20 plus additions from Bily and Mehl

Reference

Uhthoff-Kaufmann, R.R. 1988 The Occurence of the genus Strangalia serville in the British Isles. Ent.Rec. 100:63-71.

Four banded longhorn beetle . Leptura quadrifasciata formerly Strangalia quadrifasciata.

Leptura quadrifasciata (Linnaeus, 1758)

A very widely distributed albeit very local species occuring throughout mainland UK north to Easter Ross (Twinn and Harding), there are several areas with many post 1970 records; the southeast below the Thames, south Wales, the east midlands around the Humber and north Yorkshire; near coastal around Withy. Stated by Uhthoff-Neufmann (1988) to becoming scarcer. Although we have not recorded the species in our Watford area its presence should not be unexpected as they were common, in some years at least, during the late 1970's and through the 1980's at Harefield place nature reserve near Uxbridge, along the Colne valley to the south of us. The adult beetles fly readily in hot sunshine and visit a range of flowers: we have seen them on various umbels and they are known to frequent angelica, bracken, brambles, hawthorn, hogweed, meadowsweet, ragwort, rubus, spiraea, thistles, valerian and woody nightshade (Uhthoff-Neufmann loc. cit.).

The species is polyphagous with larvae developing in dead or decaying wood, especially lower parts of standing trees, stumps, felled trunks and branches down to 15cm in diameter (Alexander), they inhabit wet or dry wood but dry wood is needed for pupation. Larvae bore meandering galleries in the outer sapwood in May or June (Bily and Mehl). A wide range of hosts has been recorded including alder, aspen, beech, birch (which may be the preferred host), hazel, oak, poplar, sallow, willow, elder and also various conifers eg picea and spruce. The life cycle takes two to three years and infestations often continue for several years. Adults generally occur from June to August but have been recorded as early as March.

11-20mm. Apical antennal segments, four macula on each elytron and, in the female only, anterior tibiae pale, otherwise black. Entire body and appendages clothed with short and dense pubescence; pale over elytral maacula otherwise mostly black. Head obliquely inclined to longitudinal axis of body. Vertex roughly sculptured and depressed medially, surface below antennae, including labrum, densely punctured. Eyes transverse, anterior margin with a deep, curved incision. Temples short and prominent in front of a narrow and prominent neck. Antennae longer in male; reaching to elytral apex, in female to middle of elytra. Second antennal segment short; almost quadrate, remainder elongate. Pronotum slightly transverse; campanulate with sharp, obliquely protruding hind angles. Without lateral sculpture or margins, constricted behind front margin and with a deep transverse furrow in front of bisinuate hind margins. Surface widely depressed either side of middle, with fine and dense puncturation, the pubescence may be testaceous near the basal margin. Elyta around 2.2 times longer than broad at the humerus, surface lustrous with fine puncturation. Apices obliquely truncate or incurved, with an acute tooth at external angle and another weaker tooth at sutural angle. Legs long and robust, femora not, or only weakly, clavate. Tibiae without teeth but with two well developed spurs inside at apex. First metatarsomere as lonf as others combined. Last segment of tarsi long and curved. Claws smooth and with a small basal tooth.

Typical elytral pattern is black with four transverse testaceous macula but these may vary in extent and in extreme cases the elytra are black with a small yellow humeral spot (Bily and Mehl).

Two species may be casually mistaken for quadrifasciata. In Judolia sexmaculata (L.) the elytra are black with three transverse yellow marks and rounded apically. A mostly northern Scottish species.

In L.aurulenta the legs and basal antennal segments are red and the anterior and posterior margins of the pronotum are fringed with yellow pubescence. A rare southern, mostly near coastal, species.

Description from 1 Dyfed specimens at X20 plus additions from Bily and Mehl

Reference

Uhthoff-Kaufmann, R.R. 1988 The Occurence of the genus Strangalia serville in the British Isles. Ent.Rec. 100:63-71.

Crosses Uhthoff Rail Trail, formerly CP Port McNicoll Subdivision

October 2010, Uhthoff ON. Just messin' with some blah grey shots, adding a punch of colour. Pretty sure I went too far with this one... LOL

Part of the rail trails around Simcoe County. Uhthoff Trail.

Uhthoff Rail Trail, formerly CP Port McNicoll Subdivision

North of Orillia

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Rutpela maculata (Poda 1761) —

Black-and-yellow Longhorn Beetle

Length 13-20mm. Rather large and elongate, with distinctly tapering elytra. A variable species, but usually characterised by having bright yellow elytra with four black bands that are complete towards the elytral apex but become more broken towards the front.

Legs yellow, except for the hind femora and tibiae, which are black-tipped. Numerous colour varieties have been named (Uhthoff-Kaufmann 1996). Larvae feed for 2-3 years in damp rotting wood of various broadleaved trees, especially birch, or in pine. Adult May to September, readily visiting flowers, especially umbellifers. Widespread and rather frequent in woods in England and Wales; very local in south-west Scotland. Also recorded from Ireland.

Source :   British Wildlife, August 2007,

       Identification — Longhorn Beetles Part 1, Page 412

 TAXONOMY              

 Kingdom:   Animilia

 Phylum:     Arthropoda

 Subphylum   Hexapoda

 Class:     Insecta

 Order:      Coleoptera

 Family:     Cerambycidae

 Genus:     Rutpela

 Species      Rutpela maculata

Source : www.nhm.ac.uk/

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Gertrude Julia Clariss Uhthoff 1827 and Frances second daughter of Thomas Tindal esq and Mary Ann his wife 1835

Gertrude was the daughter of Henry Uhthoff , Frances his grand daughter. Henry was rector here in 1782 whose family came from the Low Countries. He married the grand daughter of fellow countryman Sir Joshua Vanneck serving for 65 years in the living building and enlarging the rectory.

Horse Soldiers Dirty With Atomic Number 6.

A parody of Science Fiction & Fantasy.

A 35000 word novella about knights, quests, wizards, over-weight dragons, uranium powered warhorses, chilli pizza toppings, thrutch pigs, demonic kittens, witches, 1818-mm razor-sharp boron nitride coated semi-automatic broadswords, proton zeta-rays, squirrels, fire, thunder, lightning, rain, magic, galloping steeds, pursuing enemy, inescapable doom, and a beautiful maiden to save for good measure. (warning: contains the odd naughty word)

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www.atomic6.co.uk

Near Coldwater on Uhthoff Trail

October 2010, Uhthoff ON. Just messin' with some blah grey shots, adding a punch of colour.

Part of the Trans-Canada Trail

Could use some maintenance

Uhthoff Trail

North of Orilia

Go to Page with image in the Internet Archive

Title: Weitere beitrage zum sehenlernen blindgeborener und spater mit erfolg operierter menschen

Creator: W. Uhthoff

Publisher:

Sponsor: American Printing House for the Blind, Inc.

Contributor: American Printing House for the Blind, Inc., M. C. Migel Library

Date: 1897

Language: eng

Zeitschr. fur psychol and phys. der sinnesorgane : 83.

If you have questions concerning reproductions, please contact the Contributing Library.

Note: The colors, contrast and appearance of these illustrations are unlikely to be true to life. They are derived from scanned images that have been enhanced for machine interpretation and have been altered from their originals.

Read/Download from the Internet Archive

See all images from this book

See all MHL images published in the same year

October 2010, Uhthoff ON. U-Turn...

This is what's left today of the old Orange Hall in Uhthoff, Loyal Orange Lodge #414. At one point in rural Ontario, you could find a dozen Orange halls within any given 20-mile driving radius. There were over 30 in the County of Simcoe North alone. Those were the days before Sportsnet and the UFC...

October 2010, Uhthoff ON. U-Turn...

`Uhthoff` was originally a station on the Midland Railway of Canada, and is named for Fesser Uhthoff & Co., London, England. At the time the railway was built, this firm was its agent for cargo in London. Category:Communities in Simcoe County, Ontario

Found on en.wikipedia.org/wiki/Uhthoff,_On

Out on Uhthoff Line of Severn Twp.

Steve Uhthoff tuning up