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Salient features of the structure of SVV-001. (a) Subunit organization highlighting the important loop regions in VP1 (blue), VP2 (green), VP3 (red) and VP4 (yellow). (b) Organization of the above subunits in the assembled capsid. (c) Surface-rendered image of SVV-001 showing the most exposed residues in shades of yellow and the least in shades of blue. (d) Cutaway view showing the organization of RNA (magenta) in the SVV particle. Half of the protein subunits surrounding the RNA are shown as ribbons.

Structure 16, 1555 (October 8, 2008)

Viruses are small particles composed of protein and nucleic acid that are known for their ability to cause infectious diseases, such as the flu, and some cancers. What they are less known for is their ability to treat cancer. However, this possibility has been studied since the 1950s, when the first clinical trials investigating the use of viruses to treat cervical cancer were initiated. Research has progressed in this area and new viruses have been identified that can selectively kill tumor cells. One of these is the new picorna family virus, Seneca Valley Virus-001 (SVV-001), which is unique enough to be given its own genus. In recent work performed at the BioCARS 14-BM beamline at the Advanced Photon Source at Argonne National Laboratory under biohazard safety level 2 (BSL2) conditions, researchers elucidated the three-dimensional structure of this remarkable RNA virus. This work produced important information about a new viral genus and may provide answers to the question of how some viruses specifically recognize and kill cancer cells.

 

Argonne National Laboratory.

At 8:33AM on October 27, 2019 the Los Angeles Fire Department responded to a reported structure fire at 4760 W Melrose Ave in East Hollywood. Firefighters arrived to find a two story, vacant center hall apartment building with heavy fire showing.

 

Interior fire attack immediately made entry while the truck company went to the roof to provide vertical ventilation. Heavy fire was encountered both on the first and second floors. As firefighters successfully extinguished the bulk of the fire on the first floor, the structural integrity of the building started to falter. With visible signs of pending collapse, Incident Commander Asssitant Chief Kristina Kepner made the call to transition to a defensive operation.

 

All firefighters safely exited the structure and left the roof to establish ladder pipe operations and hand lines for an exterior fire attack. 81 firefighters achieved a knockdown of the fire in 1 hour and 22 minutes with no injuries reported. A human remains detection K9 team responded to the incident to conduct a thorough search to ensure no victims were hidden under the debris. The cause of the fire is under active investigation by the LAFD Arson and Counter-Terrorism Section.

 

© Photo by Austin Gebhardt

 

LAFD Incident: 102719-0465

 

Connect with us: LAFD.ORG | News | Facebook | Instagram | Reddit | Twitter: @LAFD @LAFDtalk

Camera Sony A300 DSL

The Sacred Heart Basilica framed with Magnolia blossoms.

River Dargle Flood Defence Scheme.

These images were taken towards the end of the third week of February 2017.

 

These are the critical stabilisation works at the Silverbridge site, adjacent to the N11 dual-carriageway:

 

Back in November 2014, we'd observed bank stabilisation works here involving excavation, repair and building of a support wall structure -- carried out by JONS Construction on behalf of the National Roads Authority.

 

We would occasionally catch sight of this work in the distance. Quite an impressive little piece of structural engineering.

Having built a retaining concave wall, backfilled for solidity, they were also drilling, fixing and sealing ground anchors to pin the entire structure together.

 

flic.kr/p/paSU8U

 

Now we see that further works are being undertaken.

Word has it that extra ‘stabilisation work’ had to be done to protect the integrity of the riverbank.

At the section here we can see that there’s not much space between the edge of the rock face and the Armco at the side of the dual-carriageway.

Have yet to determine what precisely that will entail. Serious work to reinforce the side access ramp down to the river.

 

The N11 carriageway runs adjacent to this sunken side of the riverbank -- barely 2 (large) paces divide the two. Even with twin strips of Armco along the roadside, it's perilously close. Traffic speeds along this stretch (maximum speed 100 kmp). Only needs a touch from a heavy vehicle to cause secondary impact, which (worst possible scenario) could result in something going airborne.

 

Working in these confined spaces puts a premium of safety and communication.

 

The guys have hard-filled a working shelf on the riverbed, to allow machinery access to the rockface. Obviously some serious drilling is called for before a form of extra 'pinning' is put in place.

They have sunk a series of hollowed tubes/casings -- obviously to form the foundations of a more extensive structure.

And some investigative work around the transverse buttress of the access bridge, parallel to the heavy-duty pipeline carrying water down from the Vartry reservoir.

 

At a (rough) guess -- I'd say the foundations were sunk to a depth of approx 4+m.

With such secure foundations in place, they would then look to construct a substantial bank of material, and/or retaining wall (similar to that in place further along the roadside bank).

 

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Previously the guys drilled and sunk 4+metre deep reinforced tubing and rods along a newly laid concrete base. Those stubs were then used to attach steel rod cradles -- which, in turn, were filled with poured concrete. Result - the wall quickly rises. Variation on the method they've used elsewhere along this stretch of the river.

 

A continuous stretch of protective wall has now been poured, and joined up with the section originally erected back in 2014.

As we can see from the side-on shot, the base of the wall has pre-cut openings for the retaining pins that have been driven into the side wall of the roadside cliff. These have been sealed and capped.

 

Progress has been rapid, the full stretch of wall is completed, and the guys are now working on back-filling the empty space between the protective wall and the roadside rock face. You don't just throw in a few trucks loads of soil and hope for the best. You load, layer, level and compress.

 

And, at the same time, the guys are clearing away material used to build access ramps down into the riverbed.

The thought crossed my mind -- in doing so (removing the stone-filled gabions etc,) are they potentially exposing the river bank on that side to erosion, slippage etc?

We know the destructive force of fast running waters. Hell, this is precisely why the protective works have been carried out along the rest of the stretch, down to the Bray Harbour. Unless they have other plans to stabilise it, what is going to be left here is loose soil -- very close to the access road into the halting site itself.

 

Some repair/reinforcing work is going on here to protect the (old) buttress that supports the pipework carrying water to the Bray region.

  

An old cotton warehouse, waiting to be rebuild. How to maintain a modern city: modern functions in old structures = no waste of space hand volumes wit respect for the past!

Base of the Singapore flyer, huge structure by the city edge

A collaborative project combining photographs and an original music score.

Photography Derek Eyre

Music Paul Barker

www.1001pallets.com/2016/11/wow-extra-large-pallet-storag...

 

WOW - this Extra-Large Pallet Storage Shed measures 4.50m by 2.4m or about 15 feet by 8 feet. Just think of how many awesome woodworking tools you could store in this! (sorry - the Editor got excited about this possibility).

 

Extra-Large Pallet Storage Shed:

We purchased about $1100.00 of supplies on this project. That's very reasonable for the sheer size of the shed. Smaller, poorly-made tin sheds can cost as much, or more! We built the walls out of complete Euro pallets. Then, we filled in the gaps of the outside surfaces by using material cut off from the opposite deck and installed them from the inside (behind). We made the structure very durable; The shed is very strong! I used some extra treated timber that measured 22mm by 100mm (approximately 1x3" lumber) to join the two halves vertically. Additionally, we made the foundation and roof out of "American" pallets.

 

Extra-Large Pallet Storage Shed - floor and roof...and durability:

Next, I used a rubber material to cover the roof. Then, I coated the inside of the walls in a breathable waterproof membrane. Then, I used reclaimed OSB board to make the entire shed watertight. We think the shed should last 40 or more years!

   

First conceptional approach with the topic structure close-ups.

 

Shot with Nikon D5100.

ISO 1000

105 mm

f/5.6

1/320 sec

Editing in PS Lightroom 5.

struts were made by wrapping newspaper around dowels. for some struts, the dowel was left inside the rolled up newspaper.

The 10 storey, steel-clad structure, which opened in 2008 in sheffield , is given the nickname cheesegrater

Left to right: Atrium Tower, Moshe Aviv Tower (Israel's tallest structure), Twin Towers 1&2, reflection of the Elite Tower (in construction)

Dancing Rabbit is located in a county that has no building codes, which gives members a great deal of leeway in deciding what to build. They do have an environmental covenant that disallows lumber, except for reclaimed lumber and locally harvested wood. Many structures utilize clay taken right out of the ground, often combined with hay bale construction.

 

In this particular photo, there's a converted bus dwelling in the foreground (to the left), a single family home in the middle, and a 6 bedroom hay bale building in the background.

Looking SW from conveyor belt structure at recently-closed Martin-Marietta sand yard between Floyd and Brook Sts.

I-64 in middle distance

Belknap Hardware warehouses at left.

Waterfront Plaza, 325 W. Main St., under construction (right of center, with crane).

Ohio River mile 604.

Louisville, Kentucky.

Dec. 1987.

File # 87l061.

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35 mm Kodachrome.

Plustek OpticFilm 7600i and Silverfast 8.

Picture Window 6.

JPEG quality 95.

 

The Newport-Shildon electrification scheme in north east England was a coal haulage route around 30km long. It was electrified in 1915-6 using what was then a new standard of 1500V DC. Ten electric locomotives with centrally mounted twin pantographs were used to haul trains from Shildon (a railhead for surrounding mines) to the Newport yard to service industry and docks in the area.

 

Melbourne's suburban network was electrified between 1919 and 1926 - the second system in the world to use the 1500V DC standard. Work was delayed due to WWI. The same consulting engineers worked on the two systems and a one kilometre section of the England line was used as a test for the system proposed in Melbourne. As a result of this influence the lattice overhead structures used in parts of the Melbourne system closely resemble those of the Newport-Shildon system, which was abandoned in early 1935 due to declining traffic during the Great Depression.

 

This picture compares the overhead structures on straight track. On the left is an example of the then Newport-Shildon system, as seen in The Engineer, May 26 1916, page 436. On the right are analogous structures used in the Melbourne system, near Frankston which were erected in 1922. Note the contact wire for the Frankston line originally had the same 'simply supported' arrangement as the England system. An overhead renewal program in the 1980's saw new lines installed on the original structures using the 'stitched' arrangement.

Architecturally Mahasu Devta Temple at Hanol is one of the rarest examples of perfect and harmonious blend of stone and wooden structure to form one composite grand edifice. The sanctum proper is a pure stone shikhara in classical naga style. The whole wooden structure is covered with a high pitched slated pent roof surmounted by a two-tiered conical canopy over it on which a gracefully tapered kalash pinnacle stands. The roof ends and the projection of balcony are ornamented with dangling fringes a pendent corner bells which sway with the slightest movement of breeze.

 

Plan of Mahasu Devta Temple, Hanol

The stone built classical sanctum sanctorum enshrines many mohras and one bronze image. Those in front row from left to right are Chalda Mahasu (the Mahasu who keeps on moving), Devladli Devi (mother of Mahasu Devta), Kapala Bir (one of the four birs (attendants) of Mahasu Devta), and Shedkuliya (the attendant who emits the whistling sound). Behind them in the preceding order are Pavasi Devta, Kailu (a bir), Natari (polyandrous wife of four Mahasu brothers). All the face images are seated in a middle a small bronze image which is regarded as Botha Mahasu.

Entry to sanctum is restricted strictly for others except the pujari. Even he is required to undergo ritual ablution every time he enters the celestial realms; the tradition pujari of temple is a Brahmin. He is not supposed to eat meat, only eat food once a day, avoid proximity with other persons during the term of his deity as pujari.

 

Mahasu devta temple

In front of sanctum is a large room which functions as an extension to the sanctum where sacramental objects are stored. This room is called Bhandar. Entry to this room is restricted to Brahmins only. The gilded door of the bhandar is very interesting. It surface is profusely embossed with human and animal figures in a very bold manner depicting the episodes associated with the birth of Mahasu Devta. The door frame is intensively covered with coins nailed over one another through years but non of them are numismatic interest and range from recent past. The lion head is fitted with a gold brass ring that serves as a handle. Such ornamental door are common in temple near east of satluj. In front of the vestibule is a sabha mandap followed by an open frontal portico. All the four apartments of this temple are roofed separately. Vestibule and bhandar have a combined three-tiered pent roof with pyramid canopy. The frontal porch has a gable roof over it supported by two wooden pillars with an intermediate ornamental arch.

Niofoin / Nionfoin / Nioufouin (etc many various spellings seen) between Boundiali and Korhogo is famous for its Senoufo mudbrick fetish houses.

 

In the Niboladala neighborhood, the origin of Niofoin, most of the structures are traditional mud huts with thatched roofs. Among the elongated and peaked mud barns / granaries, typical in this region of Africa, and the huts of the neighbors of Niboladaba, there are two buildings known as the “fetish houses” with their imposing thick straw roofs rising higher than the others. These two monumental sacred houses guard the two fetishes that protect the town; Diby and Kalegbin. (NB - there is some interesting information on this village on the following website: kumakonda.com/en/niofoin-ivory-coast/ )

North of the SE Tacoma St/Johnson Creek Station, the light rail tracks will travel on a structure that carries trains over the ramp connecting Tacoma Street to McLoughlin Boulevard/Hwy 99E. The concrete girders of the structure are the white lines just north of Tacoma Street in this photograph.

Temple V at 57 meters (187 ft) is the second-tallest structure at Tikal. The structure consists of a pyramidal base with seven stepped levels with rounded corners. On the main façade, it has a wide staircase with balustrades. It was assumed that it was built around 650 CE, but recent carbon dating indicates a construction around 700. The pyramid has been completely restored.

 

Tikal is one of the grandest sites of the Maya civilization, located in Guatemala's northern rainforest lowlands. While some of the monumental architecture at the site dates back as far as the 4th century BCE, Tikal reached its apogee during the Classic Period (about 200-900 CE). At its peak, the city covered an area greater than 16 square kilometers (6.2 sq miles), included about 3,000 structures, and may have had as many as 90,000 inhabitants. During this time, the city dominated much of the Maya region politically, economically, and militarily, while interacting with other states throughout Mesoamerica. Tikal gradually lost both population and influence after 850, and by 950 the city was mostly deserted.

Dancing Rabbit is located in a county that has no building codes, which gives members a great deal of leeway in deciding what to build. They do have an environmental covenant that disallows lumber, except for reclaimed lumber and locally harvested wood. Many structures utilize clay taken right out of the ground, often combined with hay bale construction.

 

This picture shows an individual's "summer cottage" made of reclaimed lumber.

This shot was captured on a guided tour of 700 Bourke Street, which houses 5,000 worker bees for National Australia Bank (NAB) - it is a modern day salt mine with funkiness!!

 

The workplace design is very modern with lots of special spaces to hang out in different work groups, but I think it is a shame that individual employees do not have a sense of their own space, as no one has their own desk where they can keep a family photo or photos of their kids or pets. Obviously NAB likes to keep all employees on their toes!!

 

The building is triangular in shape, with wonderful colours that reflect local geology and space. This carries right from the lagre spaces to the decorations on the walls and window shapes.

 

This shot captures the large triangular skylights that fill the whole atrium from 14 storeys above the ground floor. Lower floors have precarious walkways that allow workers to cross from one side of the building to the other.

 

After some fiddling i now manage to store data structurally in Liferay's structures, and lift it to the website using Velocity templates.

These are the wire frame structures cover with tissue paper. I preferred the sculptures that way, but the client wanted more color and flash!!! ;-)

This magnificent structure was first erected as a Jesuit college (Colégio da Companhia de Jesus) in 1610. It was destroyed by fire in 1670 and rebuilt in 1674. It became the Governor's Palace (Palácio dos Capitães-Generais) after the Jesuits were expelled from all Portuguese territories in 1759 and served in that function until the colonial administration was moved to Lourenço Marques (now Maputo) in 1898. After that, it became the residence of the district governor.

 

After independence in 1975, the Palácio de São Paulo (usually referred to as Governor's Palace in English) was converted into a museum. It displays an eclectic collection of colonial furniture, art, a maritime exhibit, and other memorabilia. The Capela de São Paulo which is part of the complex is noted for its 17th century pulpit and altar from the Portuguese Goa colony (India).

 

The monument is dedicated to the Portuguese navigator Vasco de Gama who first landed here in 1498.

 

8-10-2015

Meadowbrook Rd

Meadow, Stricklands Crossroads, Blackman's Crossroads, Newton Grove, Bentonville

JCEMS

Plant cell structure, vector illustration (Helpful for Education & Schools)

white sands, new mexico

Architecture

 

Today we are back in the Loop and at another structure on which several famous architects separately invested their time (like Monadnock, Day 13). The Rookery was built in 1888 and stands at 209 S. LaSalle, near the head of the LaSalle Street Canyon created by the Board of Trade (and makes up my favorite stretch of street in the city. Extended sidebar here: if you’re in the area, the absolute greatest is to stand in the middle of LaSalle just north of Washington and stare south – on a Sunday at like 7:30am, there’s nobody around. It makes me feel like I can fly… maybe that’s why so much of the Batman movies were filmed on this stretch. Okay, back to the business at hand). The Rookery was built by the adored pair of Burnham and Root. Like Mies with his Crown Hall, the duo appear to have spent a bit of extra time on the structure, as it was to become their future home. As such, they used primary LEED building techniques, leaving the entire center of the building open to allow more open space, freer movement of air, and the use of natural lighting (okay, there was no LEED, but it’s funny how close they came to today’s ideal principals of Green Development – because they were designing with themselves in mind?).

 

According to legend, the Rookery was named for the temporary City Hall that occupied the site after the Chicago Fire. Akin to the City’s nickname of the Windy City (not anything to do with weather), the building was called as such not just for the pigeons and birds that roosted in the old building, but also for the residence of the rooks (shady politicians). The fact that the structure was to be on city land may have been a problem, but part of the conglomerate assembled to complete the structure included local real estate man, Owen Aldis. Mr. Aldis happened to be an old family friend of Carter Harrison, the current mayor (and eventual 5-time mayor) of the city. Against all odds, the process reportedly moved swimmingly through the city and even more surprisingly, concluded with a 99 year lease to the Rookery’s owners for a non-increasing fee of $35,000 annually (and the city was on the hook for state property taxes). Not bad when the same amount 100 years later would have cost about $400,000 once inflation is thrown into the mix. Unique for the time, the building was created entirely for commercial lease space and contained around 600 offices.

 

Burnham and Root’s building is supported with steel columns on the first two floors, which then transition to load-bearing masonry above (another transition structure like the Monadnock). As a geotechnical engineer myself, of particular interest to me is Root’s innovative design for the support of the structure. Deep foundations hadn’t yet been developed, so a creative method had to be invented to support such a massive and heavy structure on Chicago’s 50 foot thick layer of soft clay. Root’s incredible mind arrived at a solution called a grillage foundation. His idea was to use criss-crossing steel rails and beams and then encase them in a massive block of concrete. This way the loads would be distributed over a large area - today a very similar method is still being used and is called a mat foundation.

 

When the Rookery was set to open in 1888, there weren’t many potential tenants would consider leasing space so high into the sky. As a marketing tool (and also most likely for the views and low rents) Burnham and Root moved their offices to the 11th floor of the building. Their presence was a sign of confidence in their design and helped allay fears of potential clients, but it also provided unobstructed views of the swelling city to the men.

 

By 1905, the owners had decided that the ornate ironwork in the lobby had gone out of style. In order to bring it up to date, they hired another successful Chicago architect who had been in residence in the Rookery: Frank Lloyd Wright. Looking at the lobby, Wright’s influence isn’t plainly evident – he wanted to maintain general agreement with Root’s intentions for the space. He removed much of the ironwork and replaced it with gold-inlaid white marble using Root’s designs from elsewhere in the building to complete the detailing. It was to this state that the building was restored in the early 1990s. There had been one other major rework of the building in the 1930s to an Art Deco aesthetic, and much of this was reversed and the building was restored to the appearance it had in 1910. The lobby is the only surviving urban work by Wright.

 

In order to get most of these shots (and some of the stories), we took a tour of the building with the Frank Lloyd Wright Preservation Trust. The tour was only ten bucks and was wonderful – I definitely recommend it (here: gowright.org/rookery.html).

The Union Steamship building on the Esplanade at Strahan, Tasmania

 

HWW!

 

~~~ Thank you all for viewing, kind comments, favs and awards - much appreciated! ~~~

the structure was made from birch ply board, and was held together through finger joints, CAM locks and dowel joints (all of which I made myself).

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