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Faculty and students from Fresno State and the Universidad Panamericana (Aguascalientes) make cheese in the Fresno State creamery as part of the Cows to Neuron dual study abroad program, photo by Geoff Thurner, June 17, 2022, Copyright 2022.

In front of Museum of Contemporary Art, Sydney in May 2010 for Biennale

EXPLORE, EXPERIENCE AND WONDER

 

Activities to stimulate, inspire and amuse your little grey cells....

 

Art and Science on the Brain

Wonder Street Fair 7-9 April 2013

Barbican Centre, London

  

Festival of Neuroscience - BNA 2013

A unique experience with outstanding speakers presenting the latest developments in research into the brain and CNS organised by British Neuroscience Association and supported by Wellcome Trust

In Naked Knotted Neurons, a group of protesters, some injured, some choking on tear gas, escape violent confrontation with police and other forces by staggering into a safe house they find in the midst of chaos. Strangers to one another, they soon discover they are from different worlds: all were involved in protests, but in different places and times. A trio of dieties, Fate, Chance and Destiny, have gathered them together to charge them with a task: to create a new Hero to solve the world’s most intractable, knotted problems. How to get this message across? Puppets, riddles, and audience participation reveal the secrets the protesters need to fulfill this task.

 

Following their run at the International Fringe Festival in Edinburgh, Scotland, the Penn Theatre Ensemble presented the company-devised piece Naked Knotted Neurons at Annenberg Center Live on September 4th and 5th, 2015.

 

theatre.sas.upenn.edu

 

鴿子管標 / Columbus Neuron Tube

Salk #researchers and #collaborators have achieved critical insight into the size of #neural connections, putting the #memory capacity of the #brain far higher than common estimates. The new work also answers a longstanding question as to how the brain is so energy efficient and could help #engineers build #computers that are incredibly powerful but also #conserve #energy .

 

"This is a real bombshell in the field of #neuroscience," says Terry Sejnowski, Salk professor and co-senior author of the paper, which was published in eLife. "We discovered the key to unlocking the design principle for how #hippocampal #neurons function with low energy but high computation power. Our new measurements of the brain's memory capacity increase conservative estimates by a factor of 10 to at least a #petabyte, in the same ballpark as the #World #Wide #Web ."

Our memories and thoughts are the result of patterns of #electrical and #chemical activity in the brain. A key part of the activity happens when branches of neurons, much like electrical wire, interact at certain junctions, known as synapses. An output 'wire' (an axon) from one neuron connects to an input 'wire' (a dendrite) of a second neuron. Signals travel across the synapse as chemicals called neurotransmitters to tell the receiving neuron whether to convey an electrical signal to other neurons. Each neuron can have thousands of these synapses with thousands of other neurons.

Testing Ankyrin-G (which goes to axon initial segment, pseudocolored to blue) with one of my GFP constructs (the green is transfection here) and Hoechst (pseudocolored to red, highlighting cell nuclei)

 

Leica DMRE 40x

"Dixie is not from the south as her name might suggest. She is comfortable around strangers loves a good game of Candy Land. Her interests include hopping frolicking and planting herbs. She likes to put almost anything in her mouth...please be careful. Dixie is another mischeivious neuron that is a manifestation of my own rebellious neurons that cause a movement disorder.

(1)

Connectome

connectomes.org/

 

In their words:

"A connectome is a synapse-resolution mapping of connections between

all neurons in a model organism's brain. In other words, a

synapse-resolution circuit diagram of the brain. Current approaches to

mapping the connectomes of model organisms employ serial block face

scanning electron microscopy (SBF-SEM) and transmission electron

microscopy (TEM). The only connectome that has been mapped out to date

has been from the flatworm, C. elegans, which has only around 300

neurons."

 

(2)

ConnectomeViewer

www.connectomeviewer.org/

 

In their words:

"The field of Connectomics research benefits from recent advances in

structural neuroimaging technologies on all spatial scales. The need

for software tools to visualize and analyse the emerging data is

urgent. ... The Connectome Viewer application was developed to meet

the needs of basic and clinical neuroscientists, as well as complex

network scientists, providing an integrative, extensible platform to

visualize and analyze Connectomics data.With the Connectome File

Format, interlinking different datatypes such as networks, surface

data, and volumetric data is easy and might provide new ways of

analyzing and interacting with data."

 

In addition to the viewer, this site also provides quite a variety of

datasets

that can be used to test different features and functions.

 

(3)

Human Connectome Project

humanconnectome.org/

 

In their words:

"The HCP will map the human connectome as accurately as possible in a

large number of normal adults and will make this data freely available

to the scientific community using a powerful, user-friendly

informatics platform."

"Successful charting of the human connectome in normal adults will be

enormously informative. Even more importantly, it will pave the way

for studies that reveal how brain circuitry changes during development

and aging and how it differs in numerous neurological and psychiatric

disorders. In short, it will transform our understanding of the human

brain in health and disease."

 

(4)

BrainMaps

brainmaps.org/

 

In their words:

"Brain atlases have traditionally been one resolution and

non-interactive. The next-generation brain atlas is multiresolution,

highly interactive, and fully integrated with the latest research

literature. This is BrainMaps.org, a complete online brain atlas

founded on the principle that a brain atlas is a dynamic, interactive,

multiresolution research and didactic tool that facilitates brain

exploration and knowledge discovery."

 

As if that isn't enough, BrainMaps also has an API for

developers and and open source /

OpenGL-based 3D

viewer!

 

(5)

BrainMeta

brainmeta.com/

 

In their words:

"BrainMeta was established for the purpose of accelerating the

development of neuroscience through web-based initiatives, which

include the development, implementation and support of a wide range of

neuroinformatics tools, services, and databases."

 

(6)

Allen Institute for Brain Science: Brain Atlas

www.brain-map.org/

 

In their words:

"A growing collection of online public resources integrating extensive

gene expression and neuroanatomical data, complete with a novel suite

of search and viewing tools."

 

(7)

Brain Museum: Comparative Mammalian Brain Collections

www.brainmuseum.org/index.html

 

In their words:

"This web site provides browsers with images and information from one

of the world's largest collection of well-preserved, sectioned and

stained brains of mammals. Viewers can see and download photographs of

brains of over 100 different species of mammals (including humans)

representing over 20 Mammalian Orders."

 

(8)

MSU: Brain Biodiversity Bank

www.msu.edu/~brains/index.html

 

In their words:

"The Brain Biodiversity Bank refers to the repository of images of and

information about brain specimens contained in the collections

associated with the National Museum of Health and Medicine at the

Armed Forces Institute of Pathology in Washington, DC. These

collections include, besides the Michigan State University Collection,

the Welker Collection from the University of Wisconsin, the

Yakovlev-Haleem Collection from Harvard University, the Meyer

Collection from the Johns Hopkins University, and the Huber-Crosby and

Crosby-Lauer Collections from the University of Michigan.

Our purpose here is to provide some examples of ways in which images

and information from the Collections, in digital format, can be used

in educational, research and commercial enterprises. Millions of

beautifully stained sections from hundreds of different brains,

assembled in many locations over the past century can be made

available for a broad variety of purposes."

 

Want more pics?

 

Wikipedia: List of neuroscience databases

en.wikipedia.org/wiki/List_of_neuroscience_databases

 

Want more neuro imaging software?

 

UCLA: Laboratory of Neuro-Imaging

www.loni.ucla.edu/

Presynaptic microtubules (green) and postsynaptic actins (red) at neuromuscular junction 4. The neuron surface is shown in blue. Credit: Q. Wang and M. Serpe, NICHD

Date: October 2008

Medium: Digital Photography Montage

Dimensions: w 24” x h 24” (Larger and Smaller Sizes Available)

© 2008 Tony DeVarco

 

The original photo for this piece was taken on May 17, 2008 in San Francisco's Yebra Buena Gardens.

 

"The synapse is like the soul of the brain."

Jasper Johns

   

Neurons and astrocytes isolated from rat hippocampus stained for DNA (blue), neuronal-specific βIII-tubulin (green) and astrocyte-specific GFAP (red).

Neurobiology

 

Sony A7 | Leica 50 Summicron | f5 | ISO 800

The head houses the brain, a collection of about 950,000 neurons. These neurons are specialized, and they communicate with specific neighboring neurons. This division of tasks is part of why a bee's brain, which is a fraction of the size of the bee's head, can perform complex tasks that might ordinarily require a bigger brain. A system of nerves allows the brain to communicate with the rest of the body.

 

On its head, a bee has two sensory antennae. It also has five eyes -- three simple eyes, or ocelli, and two compound eyes. The compound eyes are made of lots of small, repeating eye parts called ommatidia. In each compound eye, about 150 ommatidia specialize in seeing patterns. This allows bees to detect polarized light -- something human beings cannot do.

 

Like most insects, a bee has complex mouth parts that it uses to eat and drink. The sizes and shapes of these parts can vary from species to species, but in general, most have:

  

Paired mandibles, or jaws

A glossa, or tongue

A labrum and two maxillae

The labrum and maxillae are like lips. They support a proboscis, or tube for collecting nectar.

 

images.search.yahoo.com/images/view?back=http%3A%2F%2Fsea...

In Naked Knotted Neurons, a group of protesters, some injured, some choking on tear gas, escape violent confrontation with police and other forces by staggering into a safe house they find in the midst of chaos. Strangers to one another, they soon discover they are from different worlds: all were involved in protests, but in different places and times. A trio of dieties, Fate, Chance and Destiny, have gathered them together to charge them with a task: to create a new Hero to solve the world’s most intractable, knotted problems. How to get this message across? Puppets, riddles, and audience participation reveal the secrets the protesters need to fulfill this task.

 

Following their run at the International Fringe Festival in Edinburgh, Scotland, the Penn Theatre Ensemble presented the company-devised piece Naked Knotted Neurons at Annenberg Center Live on September 4th and 5th, 2015.

 

theatre.sas.upenn.edu

 

alan, probing electrically

Painting by Machiko Edmondson. Armory Week 2009. Art Comments coverage at www.artcomments.com. New York, NY

Neural Stimulation Research. hiPSC derived neurons forming networks InVitro allows drug screening of known phenotypes. The plasticity of aligning cells combined with an electronic MIMO interface provides an environment for the study of novel cybernetic interactions.

The Calhoun School's project for Sunday, June 26.

 

"Most of the activities that create the neuron connections in brains which lead to higher-level academic research and achievement are things that require time and space and experiential education" - Steven J. Nelson, Calhoun’s head of school, speaking to the NY Times about the school's schedule.

Entry in category 4. Video loop; © CC-BY-NC-ND: Mathieu Niquille

 

Capturing this video in living mouse brain tissue, we stole few intimate minutes of the neuronal migration choreography. The high resolution allows us to appreciate the beauty of their inner dance. How often thousands of hidden and infinitely small phenomena are the anonymous ground of what we agree to call “perfection” is, to me, a drive to stay humble regarding our contribution to science.

Here we looked at the endogenously fluorescent sensing units of interneurons during their journey through the developing brain. Images were acquired every two minutes along 1h20 using the resonant mode of a Nikon A1 confocal microscope through a 60x oil-immersion objective and with a 3x digital zoom. The field of view is 70x60µm and the raw gray scale pictures were turned into REDhot color coding.

 

Neuron | Image source: gizmodo.in

Foundations of the Neuron Doctrine

(History of Neuroscience) by Gordon M. Shepherd

 

Out of their Minds: The Lives and Discoveries of 15 Great Computer Scientists by Dennis Shasha and Cathy Lazere

i102106 147

*deep in the cerebral cortex of our brains live 30 billion neurons who communicate with each other shaping our thoughts. Most are compatible, cooperative and will allow to be dominated by reason. Deep in the recesses of the brain, not much known about them live the "dark" one's, the ones we may not know or want to acknowledge their existence. They are dormant and may stay so throughout our entire lives. But beware of hate, for when out of control, in no time it will awaken the dark one's, inflaming and contaminating all the good neutrons, making murder a most likely result.

Stefan Krikl, 2005; from my diaries

p.s. best viewed on black for effect.

In Naked Knotted Neurons, a group of protesters, some injured, some choking on tear gas, escape violent confrontation with police and other forces by staggering into a safe house they find in the midst of chaos. Strangers to one another, they soon discover they are from different worlds: all were involved in protests, but in different places and times. A trio of dieties, Fate, Chance and Destiny, have gathered them together to charge them with a task: to create a new Hero to solve the world’s most intractable, knotted problems. How to get this message across? Puppets, riddles, and audience participation reveal the secrets the protesters need to fulfill this task.

 

Following their run at the International Fringe Festival in Edinburgh, Scotland, the Penn Theatre Ensemble presented the company-devised piece Naked Knotted Neurons at Annenberg Center Live on September 4th and 5th, 2015.

 

theatre.sas.upenn.edu

 

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