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Multipolar neuron in embryonic mouse brain (~E16 or so). Neuron was transfected with a plasmid expressing GFP. Blue colorization is from DAPI staining and represents DNA of nearby cells.

But you're pleased to see what you want!

A major aim of the NIH-led Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative is to develop new technologies that allow us to look at the brain in many different ways on many different scales.

Here you get a close-up look at pyramidal neurons located in the hippocampus, a region of the mammalian brain involved in memory. While this tiny sample of mouse brain is densely packed with many pyramidal neurons, researchers used new ExLLSM technology to zero in on just three. This super-resolution, 3D view reveals the intricacies of each cell’s structure and branching patterns.

 

Read more on the NIH Director's Blog: bit.ly/2TSOng1

 

Credit: Yang Lab/University of California and K. Chung/MIT

 

NIH support from: NIMH, NINDS, and NIBIB

A mouse CA1 pyramidal cell (green) is being contacted by a neurogliaform inhibitory interneuron (red). Credit: McBain Laboratory, NICHD/NIH

Hand stitched and bound shibori techniques on habotai silk

 

Image: Pinegate Photographics, Cardiff

 

Endogenous, meaning ‘from within’, refers to her own Endogenous Depression, but also to the act of giving her inner-most feelings a physical form. This series of sculptures has become the means by which she externalises her continuing battle with depression. Whilst the sculptures represent her inner self, bound by the constraints of depression, their inherent purity and beauty are a testament to the new confidence and inner peace she has gained through her art.

 

The act of hand stitching and binding the fabric is as important to her as the resulting sculpture. The concept of “the hand healing the mind” is a significant aspect of her work; the repetitive rhythmical action of stitching or binding the cloth being a meditative one. By becoming “one with the cloth” one is taken out of oneself. The act of engaging with the cloth removes one from depressive self-absorption. The realisation of her own depression has led to her preoccupation with how other sufferers envision their own condition. Her resolve is to explore/record these through an extensive series of sculptural pieces.

 

Her work records the actions found within shibori; stitching, binding, gathering, manipulating and folding - not through the expected dye process, but purely as texture and form. It was whilst in Japan as part of her Embroiderers' Guild mature scholarship studies (May/June 2002) that she first observed the artisans who had spent their entire lives manipulating cloth prior to its being dyed. As a trained musician, she was fascinated to see that the repetitive shibori actions were not only represented on the cloth as pattern and texture, but were also imprinted upon the artisans hands and minds. She wished to learn more about these traditional techniques in order that these skills would not be lost with the passing generations, whilst at the same time developing her own personal shibori vocabulary suitable for the 21st Century.

Three views of an olfactory projection neuron in the brain of an adult locust: Dorsal (top), anterior (bottom left), and lateral (bottom right). Credit: T. Miyazaki, NICHD

Dorsal root ganglia (DRG) are sensory neurons that form on the outside of the spinal cord and extend axons throughout our bodies as part of our peripheral nervous system during development. This DRG has been grown in medium conditioned by endothelial cells, and shows significantly longer axonal extensions from the center of the explant (circular region of dense staining for β-III tubulin, red) than explants grown in standard medium. Isolating the factors that are responsible for this enhanced growth is essential to understand how vascular and neuronal systems pattern together during development. These findings will be used to develop 3D model systems to study these processes and direct the angiogenic response in regenerating tissues to ultimately encourage re-innervation.

 

This image was chosen as a winner of the 2016 NIH funded research image call.

 

This image is not owned by the NIH. It is shared with the public under license. If you have a question about using or reproducing this image, please contact the creator listed in the credits. All rights to the work remain with the original creator.

 

Credit: Jonathan Grasman and David Kaplan, Tufts University

  

Silk Screen, Chine Colle, Monotype

GFP expressing neurons in the Drosophila larval (maggot) body wall. This picture was snapped from a live specimen using epiflourescence microscope equipped with an EM-CCD camera.

Neurons (also neurones or nerve cells or nerve fibers) are a major class of cells (parenchyma) in the nervous system. In vertebrates, neurons are found in the brain, the spinal cord and in the nerves and ganglia of the peripheral nervous system. Their main role is to process and transmit information. Morphologically, a prototypical neuron is composed of a cell body, a dendritic tree and an axon. In the classical view of the neuron, the cell body and dendritic tree receive inputs from other neurons, and axon transmits output signals. Neurons have excitable membranes, which allow them to generate and propagate electrical impulses. Neurons make connections with other neurons and transmit information to them via synaptic transmission. Different types of neurons have different shapes, possess specific electrical properties adopted for their function and use different neurotransmitters.

  

Blessing of the Omnissiah

   

Les neurones à GnRH (cellules visualisées en rouges) qui naissent dans le nez au cours du développement embryonnaire, utilisent les fibres olfactives (marquage vert et bleu) pour migrer dans le cerveau jusqu'à l'hypothalamus pendant la vie fœtale. De là, ils orchestreront plus tard la fertilité.

 

©Vincent Prévot ; European Research Council/Agence Nationale de la Recherche Médicale/Métropole Européenne de Lille/Inserm.licence CC-BY-NC 4.0 international

 

Image accompagnant le communiqué de presse publié le 17 septembre 2020 : "Puberté précoce : une piste d’explication pour certains cas ?" presse.inserm.fr/puberte-precoce-une-piste-dexplication-p...

 

En savoir plus :

Jusqu’à récemment, il était communément admis que c’était l’accélération de la croissance qui déclenchait la puberté. Or, une équipe de recherche de l’Inserm, du CHU de Lille et de l’Université de Lille, au sein du laboratoire Lille Neuroscience et Cognition, a découvert en 2020 chez la souris un mécanisme associé au pic de croissance prépubère et au déclenchement d’une puberté précoce. Ce mécanisme est régulé par les neurones à GnRH, les chefs d’orchestre de la fertilité, via l’expression de leur protéine Nrp1. Ces travaux, publiés dans The EMBO Journal, remettent en question les connaissances sur les déclencheurs de la puberté et ouvrent la voie à l’étude de ce mécanisme chez l’humain et à son implication possible dans certains cas de puberté précoce.

doi.org/10.15252/embj.2020104633

 

An NIH study has uncovered specialized mouse neurons that play a unique role in pain.

 

More information: www.nih.gov/news-events/news-releases/nih-study-uncovers-...

 

Credit: Jeremy and Nichole Swan

In a study conducted by NIDA intramural scientists, details of the role of glutamate, the brain’s excitatory chemical, in a drug reward pathway were identified for the first time. (Pictured –partial view of labelled neurons in reward circuitry that starts in dorsal raphe; ventral tegmental area)

 

Credit: National Institute of Drug Abuse, National Institutes of Health

A fluorescent microscopic image of neural precursors generated from human embryonic stem cells. The neural cell bodies are visible in red and the nuclei in blue.

 

This photo was taken in the lab of Xianmin Zeng at the Buck Institute for Age Research.

 

Learn more about CIRM-funded stem cell research: www.cirm.ca.gov

Two human hippocampal CA3 pyramidal cells. Credit: McBain Laboratory, NICHD/NIH

Scientists can delay death as it spreads through cells from head to tail in the nematode worm. False memories have been planted into the minds of mice using flashes of light to trigger neurons. Stem cells integrated into the retinas of blind mice can form new photoreceptor cells. A new cancer drug, PAC-1, has treated pet dogs with cancer before starting clinical trials in humans. A biodegradable silk implant stops epilepsy progressing in rats. The Mouse Genetics Project has discovered new roles for over 900 genes related to human diseases.

Transferrin receptor (TfR) is labelled red in the somatodendritic domain of hippocampal neurons. The axon initial segment (AIS) is green and F-actin protein is blue. Credit: G.G. Farías and J.S. Bonifacino, NICHD

Mamiya 6, 50mm lens

Ilford Pan F Plus film developed in Ilfotec DD-X for 8.5 minutes

Neuron by American sculptor Roxy Paine.

Knitted by my wife, Heather Brown, for Stitched Science.

@Robertmarc60 and I had our photographs made for a connectomics photo session yesterday.

 

Larval zebrafish are optically clear, allowing researchers to observe the nervous system as it develops and monitor the activity of neurons during behavior. In this image, 6 day-old zebrafish swim near the water's surface.

 

Credit: J. Swan and K. Tabor, Burgess Laboratory, National Institute of Child Health and Human Development, National Institutes of Health

The stainless steel sculpture "Neuron" by Roxy Paine. Outside the Museum of Contemporary Art, Sydney for the 17th Biennale.

Stroking the leg, and watching the electrical spikes in the nervous system.

 

As I rubbed the pinned cockroach leg hairs, the neuron spikes were visible on the iPad. They have a simple single neuron per hair system to jack into.

 

We then ran it backward, and got the leg to dance to a hip hop tun. I wanted to teach it jiu-jitsu. =)

Mouse spinal cord neuron. Nucleus in blue. Credit: S. Jeong, NICHD

The neurons all shriveled up in a ball (indicated by arrowheads) are 1 day-old, and dying.

Students study fluorescent labeled neurons in zebra fish.

Neurons receive input from other neurons through synapses, most of which are located along the dendrites on tiny projections called spines.

Two NIH-funded studies in mice are offering a possible answer about what makes sleep essential to good health. The two research teams used different approaches to reach the same conclusion: the brain’s neural connections grow stronger during waking hours, but scale back during snooze time. This sleep-related phenomenon apparently keeps neural circuits from overloading, ensuring that mice (and, quite likely humans) awaken with brains that are refreshed and ready to tackle new challenges.

 

More information: directorsblog.nih.gov/2017/02/14/how-sleep-resets-the-brain/

 

Credit: The Center for Sleep and Consciousness, University of Wisconsin-Madison School of Medicine

 

This image is not owned by the NIH. It is shared with the public under license. If you have a question about using or reproducing this image, please contact the creator listed in the credits. All rights to the work remain with the original creator.

 

NIH funding from: National Institute of Mental Health; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences

Dylan Parry Review: "Quint Baker is like no other artist you have heard. Audio art’s dark fiend meets friendly bright pop. He inhabits a strange world. If you could take a David Lynch movie and condense it into words, liquify it and pour it into your ears, that’s what it would sound like. At first it is unaccessible, but with further listening it reveals itself, not as harsh, critical art snob noise, but fragile, flawed, delicate, sensitive and personal.

 

There is a recurring theme in many of these songs, a broken mirror, pieces of things, memories, tunes, pictures, a collage of past events. In fact these songs, if that is what you want to define them as, are in fact made up of broken pieces, samples, poetry, memories, tunes, snyths, drum beats, guitar strums. This is perhaps resonates in the collage art of Quint Baker where the commercial and horrific meets beauty in it’s natural form."

 

"Really Hot Girl" Quint Baker opens with a catchy loop “Something in my mouth, something you wanted to say, given up, given up, you have given up, you gave up?” The song then descends to the bottom floor to the boiler room, where the steam powered machines manufacture and process the notes and neurons of his music. A Japanese assembly plant that uses Just In Time inventory systems to deliver efficient sized parcels of plastic noise in small non-degradable zip lock bags. The rural workers eat blue fin tuna for lunch if they meet production quotas. The lunchroom it is much more relaxed as they drink sake and sing karaoke before the next shift and yell the factory Tri-slogan at each other ....... Transmation ( a form of transformation or mutated change ) Prostitute ( a form of relaxation, a reward for meeting production quotas) Rings of power ( Myth of the Qunag emperor who promised only his most loyal subjects everlasting strength and riches) .....before the floor manager, a dark little man with shrunk shoulders sends them home with their meager rations, a handful of rice and plastic yen. Symbols of wealth, modernity and power, icons of steel and overseas holidays in Florida. What was in his mouth? Well something that people want to say, but they never do, only Quint Baker can/does and tries." .................... "This is so unconventionally stunning and beautiful, Sad.

 

"The Girl In the Wind" If there was a genre for music called strange/haunted/beautiful then this would be my favourite song of this genre ever!! Strauntful music? Made up of only a fragment of a lyrical line Pick up the pieces , pick up the memory..of the girl, this line contorts and distorts into the sublime of the girl... of the girl.... of the girl..., a strong fragment of a memory where this song reminisces , a regret maybe, an Alice in Wonderland moment as she floats onto a bright green field, a cold grey beach, but he is unsure if this place was real, was he there, it is only a piece, broken, sharp, painful but smooth, clear and beautiful.... this song now haunts me too..."

 

"Tree Auras" Tree Auras is onboard the SS Baker, the sole submarine in the Royal New Zealand Navy. A trade deal that was made with the Ukrainian Government after the fall of Communism. The NZ ministry of defence made a covert deal with party members for a small four man submersible, 40 tonnes of milk soilds and a phototype design for KZ7. The details of this submarine remain classified, however, a former crew member has leaked sensitive information to local ears. The submarine is on permanent routine patrol beneath the shore of lake Te Anau at a depth of over 1000 meters. It’s wipers, cleaning prehistoric algae from the cockpit window, the only sound within the steel hull. The crew work as part of a joint venture with the department of conservation looking for proof of early viking landings upon long lost glaciers. The crew drink tea, play cards and gossip as they peer out of the port holes through the dim light looking for distinctive hulls. All they ever see are giant petrified kauri forests coated in green luminous decay like staring at a giant coral reef with night vision goggles. I am fast becoming a BIG fan of your music, as you say "Audio art", but blurred into the pop realm. Girl in the wind is still stuck inside me, something about that song. I can find no other way to review your music but with stories as they are one."

 

"Hand A love song among the moss and lichen of a south island beech forest, hairy hobbits and fairy frost, the delicate balance of nature may have been disturbed. Martin Phillips built himself a hut here, for song writing and time alone. But with the damp and faded light his guitar grew moss and his strings turned into vines and grew into his fingers. Then his fingers grew around his guitar, and his toes became rooted to the ground. Then he began to drink from the ground and his guitar vibrated, his skin turned to bark. As he grew he sung, deep inside his hard wood heart, the rings of time wound round and round and his branches grew, up, until he was tall as all the other trees and he could see all around the forest. He hated it there, the sun too bright, obvious, dry and unyielding. So he withered, down, descending and rotting, until he was earth. There he relished the warm decay, soft, moist and caring. There he waited and slept listening to the rain and the birds. When the time came he grew, fingers first, then hands, arms, elbows, shoulders, head, torso, waist, thighs, legs and feet. He walked out of the forest, guitar on his shoulder with a song to sing. "

 

"Crying for your Younger Days An airport, where all flights are delayed, the gates are empty, announcements are made of apologies and further delays. Shrivelled grey people wait holding their hand luggage, sleeping or slouched on seats like refugees. The only place open is a bar which is full. As people wait a man sings into a broken mirror songs about someone he new, a girl, a love, he loved her. Nobody listens, or cares......”Crying for your young days,.......Living the memory of you....” Over and over and over and over. Awaiting passengers have no idea of how long they have been waiting here, most have forgotten there own names, or what flight they are catching, but they all listen to the annoucements and gather round the gates like ghosts. It is always night and new passengers arrive at the airport out of grimy taxis, always alone and always lost. They check in, and wait, try to remember, drink coffee. Eventually they walk in to the bar where the man sings in to broken mirror” Crying for your young days,.......Living the memory of you....” By then they have forgotten, but the man with the mirror knows them and he smiles, he knows who they are."

 

"Blossom Tree Talk back dance radio where ranters and ravers stay up all night long. “The wee hours on 1255 fm", run by hedgehogs who dine on pot noodles, instant coffee and snails. “ The topic tonight is electro mechanics.” “ Our lines are open” A local hedgehog spins and scratches records as callers voice their opinion and hate. The host spits and preaches with his foul snail breath. Some listeners dance, others just listen and nod their heads sometimes to the music, sometimes to the words. It is Ad free, on 1255 fm"

 

"Touch play on the tape recorder" It is Top of the Pops in 1984 and on stage is Quint Baker, pop revisionist/anarchist, playing inside a giant magnetic reel. He has stars in his eyes. Quint Baker 2010 still thinks it is 1984. He relives his glory days in South Island Pokie bars on Tuesday nights. He signs autographs to disillusioned youth and alcoholics, professing his abstract thoughts and feelings on art and music, but they just smirk and he kind of knows this. But he gets on stage anyway, dressed in a white boiler suit with only a disco light left over from the Saturday Night Fever theme night last Thursday. He plays earnestly with his keyboard, playing stunning layers of sound and he jerks his body to his words “ Touch play on the tape recorder, I found it for you....” his eyes closed as Tammy and Shona up from Invercargill get up and dance, their rum and coke RTDs spilling onto the beer soaked carpet. Sadly beautiful and melancholic this song brings a tear to the eye of one patron as it reminds him of a girl he knew, once. "

 

"Egg Spring", Egg Spring is set in the Democratic People’s Republic of Korea(DPRK). Deep under the Amnok river, running along the Demilitarised Zone, lies the Propaganda and Agitation Department’s New Development Bunker(NDB), a personal pet project of Kim Jong-il. Under pressure from new Security Council resolutions prohibiting further nuclear testing, Kim Jong il has instead redirected his top scientific staff into developing new nano technology. These tiny robots, each a perfect miniature version of himself are his new arsonal against the West. Each wind up soldier is capable of entering a human being through the skin. Once inside he quickly travels to the brain and proceeds to cut neural links and build new ones, slowly changing the host’s thought patterns and personality. It is rumoured, through unofficial intelligence reports, that millions of these “Nano weapons” have already been released. Infected hosts are not easily indentifiable, although again unofficially, a source within the National Clandestine Service, formerly the Directorate of Operations, which performs clandestine intelligence collection and covert action, has claimed the hosts can be indentified only through behavioural analysis. Typical symptoms include political apathy, non selective preferences or opinions towards literature, art or music, impulses and interest in new economic theory and wide eyes while watching television. What is unknown is what will happen once these “hosts” are activated."

A neuron from the AIs of the future?

 

This has NOT been photoshopped.

Was created using long exposure and various LED lights.

More brain cells. The ring of cells are astrocytes and blue are neurones.

www.medical-explorer.com/alzheimers.php

Hallmarks of Alzheimer's disease include neuritic plaques,(outside neurons), and neurofibrillary tangles (inside eurons).

 

¿ me-zoh-NYOOR-on ? -- Greek: meso (middle) or meizon (greater); neuron (nerve) ... GBIF

kuk-yoo-LAY-tuh -- hood-like, hood-shaped ... Dave's Botanary

 

commonly known as: hooded-flowered brasiletto, Sahyadri thorn • Assamese: বাঘাচোৰা baghasora, বাঘ-আঁচোৰা bagh-anchora • Bengali: বগাছেঁড়া কাঁটা bagachera kanta, বাঘাসোরা baghasora, বাকশিকাঁড়া bakshikandra, বিষখোপরা biskhopra, নাটাকুলা natakula, নিয়াঙ্খুপঝু nyankhupajhu • Hindi: बिसखपरा bis-khapra • Garo: jakshil, mengojakskel • Kannada: ಮಟ್ಟ ಸೀಗೆ matta seege, ಮುಳ್ಳೋಡು ಬಳ್ಳಿ mullodu balli • Konkani: वाकेरी vakeri • Lepcha: neangkupzhu • Malayalam: കാക്കക്കലിംഗിവള്ളി kakakalingivalli • Marathi: रागी ragi • Mizo: ling-khang • Nepali: बोक्सि काँड़ा boksi kanra • Nyishi: pani pgig traw • Odia: ନିତେ nite • Santali: ᱵᱟᱜᱷᱤᱱ ᱡᱷᱟᱣᱟ baghin jhawa • Tagin: pani pgig traw • Tamil: இண்டு indu, மாட்டிச்சீங்கை matticcingai • Telugu: గబ్బుసీకాయ gabbusikaya • Urdu: بس کهپرا bis-khapra

 

botanical names: Mezoneuron cucullatum (Roxb.) Wight & Arn. ... synonyms: Caesalpinia cucullata Roxb. • Caesalpinia monosperma Buch.-Ham. ex Wall. • Caesalpinia wynaadensis B.Heyne ex Wall. • Mezoneuron grande B.Heyne ex Wall. • Mezoneuron macrophyllum Benth. ex Miq. ... POWO

Mouse spinal cord neuron. Nucleus in blue. Credit: S. Jeong, NICHD

More experimental Photography...

 

No lights were used in this photo, no editing was done, xcept a crop

 

light is from self luminescence chemicals inside a glow in the dark light stick (the ones you break an shake) poured onto a those plasticky bubbles that we used to blow up when we were kids... apparently the chemicals poured onto bubbles make them shrink an go webby an gooey like!!!

 

loved these shots....shot in complete darkness

On the larval body wall, labeled with a membrane anchored GFP (mCD8:GFP).

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