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"Tropical Depression" Harvey slowly taking over the Southeast. According to NOAA this "depression" was passing through Mississippi while kids played basketball here in Louisville, Kentucky, USA. Looks like this harmless "depression" might need some Prozac. www.nhc.noaa.gov/graphics_at4.shtml?cone
We visited Mohammed Ali's grave site in Louisville, KY, USA and it is indeed a beautiful site. It is said he wanted a modest burial place. The caretaker there today noted Ali had come himself to choose this particular site, and well chosen it is. In comparison with other memorials in this cemetery, it is indeed humble, beautifully designed, maintained and watched over. There are benches on each side of the steps if one wishes to sit and reflect and there is a small urn where passersby drop change after walking up a small grouping of solidly placed stone steps. It is beautifully landscaped with petunias, dahlias, ivy, begonias and other bright, colorful flowers. This is definitely a peaceful, inspiring place and well worth the visit. Pictured: Nadia and David.
About our friend, Nadia:
Nadia Kennedy (adopted name), born 10/16/98, was possibly born in Kiev, Ukraine. She relays that her birth parents in Russia were reported to the government as being addicts and alcoholics and their neighbors called the police on them. Both babies (or toddlers) Nadia and her sister were removed from the home and placed in separate "baby houses", aka a place where they sorted out babies to determine which were healthy enough to stay in Russia and which would be offered out to other nations for care and adoption.
Nadia stated her sister is one year younger than she is. Her sister's birthday is 8/4/99. She wants to locate her sister. Please do share this link/photo with anyone you know who might know the whereabouts of her long lost Ukraine sister.
Nadia says she was born with fetal alcohol syndrome. You can read about fetal alcohol syndrome here: www.cdc.gov/ncbddd/fasd/facts.html
Her maternal adopted Grandparents currently reside Woodbury, NJ. Her adoptive parents currently reside in Florida.
Interestingly enough, 2 1/2 years later, this mushroom planted itself adjacent to this Sons of the American Revolution Blankenbaker family grave marker at the cemetery located on Papa Johns Pizza's property.
Once it was one of the largest brick homes in Charles County, Maryland. Once it was the site of an amusement park. Once it was burned by arson. Once a truck drove through the middle. And now...
In speaking with the nice guard outside today, he says Amgen is a laid-back place to work and the noise levels are typical for a warehouse. It is a large shipping warehouse for cancer treatment drugs. They recently expanded.
12000 Plantside Dr, Louisville, KY 40299
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From Wikipedia - a little history:
The company has made at least five major corporate acquisitions.
Timeline
1980. William Bowes from Cetus Corporation recruits Winston Salser from UCLA to start Amgen with a scientific advisory board consisting of Normam Davidson, Leroy Hood, Arnold Berk, John Carbon, Robert Schimke, Arno Motulsky, Marvin H. Caruthers, and Dave Gibson.[7]
1989. Amgen received approval for the first recombinant human erythropoetin product, Epogen, for the treatment of anemia associated with chronic kidney failure. Epogen (also marketed by Johnson and Johnson under the tradename Procrit) would later be approved for anemia due to cancer chemotherapy, anemia due to treatment with certain HIV drugs, and for the reduction of the need for transfusions associated with surgery.[8]
1991. In February 1991, Amgen received FDA approval for Neupogen for the prevention of infections in patients whose immune systems are suppressed due to cancer chemotherapy.[9] A 2002 meta-analysis found that Neupogen treatment reduced the risk of febrile neutropenia by 38%, reduced the risk of documented infection by 49%, and reduced the risk of infection-related mortality by 40%.[10]
1998. In November 1998, Immunex, a future acquisition of Amgen, received approval for Enbrel (etanercept), the first rheumatoid arthritis drug targeting tumor necrosis factor alpha (TNF-alpha).[8] A 2006 assessment by the National Institute of Clinical Excellence of the United Kingdom concluded that etanercept and related rheumatoid arthritis drugs later introduced by competitors "are effective treatments compared with placebo for RA patients who are not well controlled by conventional DMARDs, improving control of symptoms, improving physical function, and slowing radiographic changes in joints."[11] A more recent study demonstrated that compared to traditional disease-modifying anti-rheumatic drugs, treatment with etanercept improved survival, reduced cardiovascular events and reduced the incidence of hematological cancers.[12]
2010. On June 6, 2010 Amgen received FDA approval for Prolia, a protein drug for the treatment of post-menopausal osteoporosis.[13] In clinical trials, Prolia reduced the rate of vertebral fractures by 61% and the risk of hip fractures by 40%.[14]
2010 In November 2010 the FDA approved Xgeva for the prevention of complications of bone metastases in patients with solid tumors.[15] The clinical trials primarily enrolled patients with breast or prostate cancer.
2012. Illegal marketing practices. The Los Angeles Times reported on December 18, 2012, that AMGEN pleaded guilty and agreed to pay $150 million in criminal penalty and $612 million to resolve 11 related whistleblower complaints. Federal prosecutors accused the company of pursuing profits while putting patients at risk.[16] Larry Husten, a contributor at Forbes.com elaborates on AMGEN's illegal marketing practices in this case, namely that the "government accused Amgen of marketing Aranesp for indications not approved by the FDA and other illegal marketing practices".[17] One of the drugs mentioned in the lawsuit had sales of $492 million in the third quarter of 2012, down 17% from the same quarter the previous year due to "reimbursement problems and label changes".[18]
2012. Amgen paid $762 million after pleading guilty to criminal charges of improper promotion and sale of misbranded drugs.[19]
2013. Lawmakers inserted text into the fiscal cliff bill that will allow the drugmaker to sell a class of drugs that includes Sensipar without government controls for an additional two years. The New York Times estimated that the paragraph in the fiscal cliff bill will cost taxpayers an estimated $500 million[20] but other assessments concluded that the change would protect seniors in rural areas and reduce overall Medicare spending.[21][22]
2015. In September the company announced it would acquire Dezima Pharma for more than $1.55 billion.[23] The same day the company announced a collaboration with Xencor on 6 early stage immuno-oncology and inflammation programmes. As part of the deal Amgen will pay $45 million upfront, with the deal being worth up to another $1.7 billion.[24][25]
2016. In September, the company announced it would purchase the rights to Boehringer Ingelheims Phase I bispecific T-cell engager compound (BI 836909, now AMG 420) for use in the treatment of multiple myeloma.[26]
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From the Wall Street Journal 5/29/21: A pathbreaking pill for lung cancer from Amgen Inc. was approved by the U.S. Food and Drug Administration, adding a new potential blockbuster to the biotech giant’s aging stable of drugs.
The drug, called Lumakras, was approved Friday to treat a portion of lung cancer patients with a particular genetic mutation who have already tried other therapies.
The mutation, known as KRAS, is among the most common found in cancers, but researchers struggled for so many years to find a medicine that can treat it that the mutation came to be considered “undruggable.”
Amgen Wins Approval for Pathbreaking Lung Cancer Drug (By Joseph Walker
Updated May 28, 2021 3:42 pm ET): www.wsj.com/articles/amgen-wins-approval-for-pathbreaking...
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It is ironic that stem-cell treatment is used in other Nations successfully in combating cancer, yet not in the USA.
While Pancake and I were out and about this morning we thought we'd drop in (walked right in) on a local health care company. What I found interesting is their login book for visitors contained entries for a company called C2 Strategic Communications. C2 is Louisville Mayor Fischer's PR firm. They are also serving as spokesperson for RiverLink, the fiasco behind the Ohio River toll collection system and the Ohio River Bridges Project (aka EZPass, Kentucky Style), MSD, The Liquor Barn and the Louisville Water Company. It is my feeling that if one enters ANY place of business as a professional - especially a health care company where enormous amounts of customer data, vendor and Government information is readily available, it would behoove C2 Strategic Communications to comply with that company's request for credentials, logins and logouts, because for some, accuracy and accountability DOES matter - especially in the health care field as all of our lives, information, confidentiality, health and wellbeing depend on it. That is all.
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C2 Communications Experience
No substitute for
EXPERIENCE
We’ve been called a lot of things over the years: reporter, editor, spokesperson, adviser, speechwriter, photojournalist and more.
That’s why we are so good at what we do today.
We have decades of experience in newsrooms, board rooms, classrooms and situation rooms.
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Chad Carlton
President
Chad Carlton brings more than 25 years of high-stakes, front-line communications experience to the leadership of C2 Strategic Communications. He is a strategic and creative thinker, a polished writer and a respected adviser to strong leaders including governors, mayors, company executives, cabinet secretaries and entrepreneurs.
Kerri Richardson
Executive Vice President
Kerri is a communications leader respected by both newsmakers and journalists for her communications savvy, insight, candor and grace under pressure. She served as communications director and chief spokesperson for Gov. Steve Beshear, leading policy messaging across the Executive Branch.
Mindy Peterson
Vice President
Mindy Peterson’s familiar and trusted voice has guided citizens, motorists, leaders and journalists for more than two decades. Mindy has served as primary spokesperson for one of America’s largest and most complex transportation construction projects, the Ohio River Bridges Project’s Downtown Crossing. She’s also introducing the region to all-electronic tolling, serving as spokesperson for RiverLink.
Ed Green
Senior Strategist
Ed Green knows business inside and out. He’s respected by CEOs and corporate leaders throughout the region for the fairness and insight he displayed during two decades as a business reporter and editor at Louisville Business First and The Courier-Journal.
Nolan Miles
Staff Strategist
Nolan Miles is a young, energetic public-relations professional with a passion for storytelling and a knack for digital communications. His skills run the gamut, from website copy writing to social media collaboration and graphic design. And as the firm’s staff strategist, Nolan has his hands on a wide variety of C2 Strategic projects.
Beverly Bartlett
Senior Strategist
Beverly is an engaging writer, a trusted advisor and a social media maven. As a leader of Louisville Mayor Greg Fischer’s communications team, she was the voice behind the voice of Louisville.
Kaitlin Keane
Communications Coordinator
Photojournalist Kaitlin Keane spent years honing visual storytelling skills in community newspapers, developing new ways to connect meaningful content with readers. She created can’t-look-away photo essays and videos for newspapers in Texas, Minnesota, Tennessee and Kentucky, and gathered a slew of photojournalism awards along the way.
Paige Moore
Senior Strategist
Paige is passionate about applying research and data to develop strategies that reach the right people and move them to action, particularly using digital channels. She has nearly two decades of experience in content, marketing and user experience strategy at Fortune 100 corporations and digital agencies in Louisville and Indianapolis.
LeAnn Swanson
Business Manager
As business manager, LeAnn keeps the C2 Strategic operations running smoothly, drawing on 35 years of experience. Between financial reporting and office management, LeAnn balances more than just debits and credits.
Dr. Beanes being held captive by the British was the incident that led to Francis Scott Key being held offshore of Fort McHenry and writing a poem that became the Star Spangled Banner.
盼我瘋魔，
還盼我孑孓不獨活。
想我冷艷，
還想我輕佻又隨便。
攝影 戴群芳【Fong】女子攝影美學
主角👸 Fairy 雨䕕
場地🌼 R-room 攝影棚 / 場地租借 · 攝錄影服務
造型💄 Ginger makeup造型團隊
禮服💃 Lin Hui Chi Haute Couture 林卉祺高級訂製服
美鞋👠 ReSarah 時尚手作婚紗鞋/伴娘鞋/晚宴鞋/蜜月鞋
#ThisAttackComesFromTaiwan
#letsguide #Taiwan 🇹🇼
#Nikon #instagood
#DslrPhotographer
#戴群芳女攝影師
#LinHuiChiHauteCouture林卉祺高級訂製服
#GingerCMakeupHairArtist
#ReSarah時尚手作婚紗鞋
#Rroom攝影棚 #板橋
Cheltenham Wetlands Park was once part of the U.S. Naval Radio Station, Cheltenham, Maryland. It was commissioned in 1939.
“The original antenna fields, comprising creosoted wood telephone poles and metal antenna towers, were located in the acreage surrounding the buildings. All metal antenna poles have been removed from the installation. Some abandoned creosoted wood poles remain in the wooded and swampy sections of the installation.
Established as a radio receiving station before World War II, the installation's mission evolved to administration during the Cold War era.”