View allAll Photos Tagged embolization.
The artery seen in this image is occupied by typical hydrophilic polymer emboli. The patient had peripheral vascular disease requiring amputation of a toe.
Hydrophilic polymers are widely used as surface coatings on vascular medical devices including guidewires, introducer and delivery sheaths, implantable stents and coils as well as cardiac, central and peripheral catheters. These polymers can fragment and embolize to various organs, most commonly the lungs. If they originate from the left side of the heart, embolization throughout the systemic circulation may occur. Their microscopic appearance is that of intravascular, coiled, worm-like structures. They can produce ischemic changes and infarction.
Image contributed by Dr. Eduardo Alcaraz - @edusqo
Hydrophilic polymers are widely used as surface coatings on vascular medical devices including guidewires, introducer and delivery sheaths, implantable stents and coils as well as cardiac, central and peripheral catheters. These polymers can fragment and embolize to various organs, most commonly the lungs. If they originate from the left side of the heart, embolization throughout the systemic circulation may occur. Their microscopic appearance is that of intravascular, coiled, worm-like structures. In this case they embolized to the kidneys and lodged in glomerular capillaries. A comprehensive review of this subject is available at tinyurl.com/yyy8y7qp.
Image contributed by Dr. Jean-Baptiste Gibier - @ljeb
Therapeutic embolization of polyvinyl alcohol microspheres or particles to the lungs is usually undertaken for treatment of lung hemorrhage. The PVA particles and microspheres may each incite a foreign body giant cell reaction which is not seen in this image.
Images contributed by Dr Irene Sansano - @SansanoValero
Hydrophilic polymers are widely used as surface coatings on vascular medical devices including guidewires, introducer and delivery sheaths, implantable stents and coils as well as cardiac, central and peripheral catheters. These polymers can fragment and embolize to various organs, most commonly the lungs. If they originate from the left side of the heart, embolization throughout the systemic circulation may occur. Their microscopic appearance is that of intravascular, coiled, worm-like structures. They can produce ischemic changes and infarction. A comprehensive review of this subject is available at tinyurl.com/yyy8y7qp.
Image contributed by Dr. Amparo Benito Berlinches - @AmparoBenito
CrospovidoneIt has a coral-like appearance and is an insoluble polymer of N-vinyl-2-pyrrolidone that is used as a disintegrant in pharmaceutical tablets. It embolizes to the lungs when aqueous suspensions of pulverized tablets are injected intravenously in drug abusers. It is also found in the gastrointestinal tract following ingestion of various types of tablets. The precise architecture of histologically processed crospovidone can vary by medication. This and other features of crospovidone are very well discussed and illustrated in tinyurl.com/yajl3oru.
Images contributed by Dr. Pooja Navale - @navale_pooja
Microspheres impregnated with the radioisotope Yttrium-90 (Y90, 90Y) were used to treat a neuroendocrine tumor that had metastasized to the liver. These microspheres are selectively delivered through the hepatic vasculature to the target tumor(s). Tumor shrinkage is the result of both radiation and ischemia. These Y-90 coated microspheres/embospheres may incite a foreign body granulomatous reaction which is not seen in these images.
Images contributed by Dr. Raul S. Gonzalez - @RaulSGonzalezMD
Intravascular embolized microcrystalline cellulose with a foreign body giant cell reaction. Microcrystalline cellulose is used as a filler in pharmaceutical tablets. It embolizes to the lungs when aqueous suspensions of pulverized tablets are injected intravenously.
Image contributed by Dr. Yale Rosen - @yro854
Painting illustrating plaque rupture, fibrin strand / platelet mesh, coronary blood flow, and embolization to the microvasculature. Installed in a corporate board room. 4 foot by 4 foot.
The small vessels of the lung, including pulmonary capillaries, are filled with this tan material which was likely injected intravenously. Can anyone identify this material.? It has been suggested that this might be embolized bone cement.
Image contributed by Dr. Yale Rosen - @yro854
Images from: Mehta RI et al. Modern Pathology (2010) 23, 921–930 (tinyurl.com/rkjztaj)
Hydrophilic polymers are widely used as surface coatings on vascular medical devices including guidewires, introducer and delivery sheaths, implantable stents and coils as well as cardiac, central and peripheral catheters. These polymers can fragment and embolize to various organs, most commonly the lungs. If they originate from the left side of the heart, embolization throughout the systemic circulation may occur. Their microscopic appearance is that of intravascular, coiled, worm-like structures. They can produce ischemic changes and infarction.
This is a gallbladder from a patient who had trans-arterial radioembolization of a liver neoplasm. Some of the radioactive yttrium beads got into the gallbladder and resulted in infarction.
Radioembolization is currently used to treat primary liver cancer (HCC) and liver metastases of colorectal carcinoma. The treatment involves injecting tiny microspheres with low levels of radioactive material into the arteries that supply the tumor.
Millions of 30-micron beads are infused through a catheter into the hepatic artery and become embedded in the liver. The beads are bonded with yttrium-90 (Y-90). Y-90 is a beta-emitting radionuclide that acts locally at the tumor site. The beta particles travel 11 mm, at most, due to their relatively low energy. This allows the beads to embed into and irradiate the tumor while healthy liver tissue is spared.
Information on radioembolization from tinyurl.com/y58h9hyn
Images contributed by Dr. Elizabeth Montgomery - @LizMontgomeryMD
USA Fibroid Centers, we believe you shouldn’t have to choose between continued suffering and an invasive procedure. Our interventional radiologists use the gold standard in non-surgical fibroid treatment — Uterine Fibroid Embolization (UFE). This procedure treats fibroids and prevents the growth of new tumors without removing the uterus. We perform this treatment at our outpatient centers, which means you can go home the same day.
This chart shows the distinguishing features of poylvinyl alcohol (PVA) particles and microspheres and trisacryl gelatin microspheres (TGM) that are utilized for uterine artery embolization for treatment of symptomatic uterine leiomyomas,
Uterine artery embolization (UAE), performed by interventional radiologists, is a frequently utilized alternative to surgical treatment of symptomatic uterine leiomyomas (fibroids). The goal of embolotherapy is to produce infarction and, thereby, shrinkage of the leiomyomas.
A variety of embolic agents are approved by the U.S. Food and Drug Administration (FDA) for UAE. These include tris-acryl gelatin microspheres (TAGM; Embospheres, Merit, South Jordan, UT) , nonspherical and spherical polyvinyl alcohol (PVA) particles (various manufactures), calibrated acrylamido polyvinyl alcohol microspheres (a-PVAM; Bead Block, BTG, West Conshohocken, PA). Polyzene F–coated microsphere (Embozene, Boston Scientific) is the most recent addition of embolic agents for UAE. This agent consists of a hydrogel core of polymethylmethacrylate and a flexible shell of polyphosphazene, a synthesized inorganic biostable and biocompatible polymer.
Follow-up studies utilizing surgical specimens have shown that the embolic material is mainly present in leiomyomas and non-neoplastic myometrium but is also found in non-targeted sites such as cervix, endometrium, ovaries and fallopian tubes. Infarction is confined to leiomyomas.
Embolic material can cause vascular damage resulting in pseudoaneurysms. These are thought to be responsible for the finding of embolic material in extravascular spaces, usually in close proximity to damaged arteries.
The assistance of Dr. Monika Vyas - @Mvgs1706 is gratefully acknowledged
References:
-Maleki Z et al. Int J Gynecol Pathol; 2010; 29:260-268
-Chiesa AG, Hart WR. Int J Gynecol Pathol; 2004; 23:386-392.
-Kohi MP, Spies JB. Updates on Uterine Artery Embolization. Semin Intervent Radiol. 2018;35(1):48–55. doi:10.1055/s-0038-1636521
Hydrophilic polymers are widely used as surface coatings on vascular medical devices including guidewires, introducer and delivery sheaths, implantable stents and coils as well as cardiac, central and peripheral catheters. These polymers can fragment and embolize to various organs, most commonly the lungs. If they originate from the left side of the heart, embolization throughout the systemic circulation may occur. Their microscopic appearance is that of intravascular, coiled, worm-like structures. In this case they made their way to a paraganglioma. A comprehensive review of this subject is available at tinyurl.com/yyy8y7qp.
Images contributed by Dr. Frank Ingram - @Chucktowndoc
These embolic microspheres were seen in a TURP specimen following prostatic artery embolization for BPH. The type of microsphere is not known.
Images contributed by Dr. Sara E. Wobker - @SaraEWobker
Embozene® microspheres are spherical, tightly calibrated, biocompatible, non-resorbable, hydrogel microspheres coated with an inorganic perfluorinated polymer (Polyzene®-F). They are available in a range of sizes suitable for embolic therapy. Embozene® Microspheres are available as colored and opaque (non-colored) microspheres. Colored microspheres are color coded by size.
In this case they were therapeutically embolized to the liver to treat a hepatic neoplasm.
Images contributed by Dr. Michael Feely - @MFeelyDO
Therapeutic embolization is a procedure in interventional radiology that is most commonly used to treat arteriovenous malformations hypervascular tumors , including uterine fibroids and hepatoma and symptomatic BPH. A wide variety of agents, both temporary and permanent, are available and each has its own place and use. This image shows spherical microspheres, permanent agents, that are manufactured from synthetic materials that vary in diameter according to the size of the vessels that one is seeking to occlude. This is a case of cystic fibrosis-associated bronchiectasis complicated by hemoptysis that was treated with bronchial artery embolization.
Image contributed by Dr. Sanjay Mukhopadhyay - @smlungpathguy
Therapeutic embolization of triasacryl-gelatin microspheres (Embospheres®) to the lungs is usually undertaken for treatment of lung hemorrhage. These microspheres range from 0.16 - 0.65 mm in diameter with a mean diameter of 0.43 mm. With H&E staining this material has a distinctive, strong resemblance to thyroid colloid.
Images contributed by Dr. Sanjay Mukhopadhyay - @smlungpathguy
Resection of upper lobe of right lung for recurrent hemoptysis. Previous history of pulmonary tuberculosis with a provisional diagnosis of fungal mass (aspergilloma).
Patient treated for hemoptysis by emobilization with polyvinyl alcohol (PVA) particles. PVA microspheres are also utilized for therapeutic embolization. The PVA particles and microspheres may each incite a foreign body giant cell reaction as seen in these images.
Images contributed by Dr Rajesh Panth
Embolization performed by Dr. Om Biju Panta
Filters, such as this one, are inserted into the vena cava to prevent thrombi from the lower extremities from embolizing to the lungs. A thrombus is present next to the filter.
Image contributed by Dr. Yale Rosen - @yro854
Intravascular embolized microcrystalline cellulose with a foreign body giant cell reaction. Microcrystalline cellulose is used as a filler in pharmaceutical tablets. It embolizes to the lungs when aqueous suspensions of pulverized tablets are injected intravenously.
Image contributed by Dr. Yale Rosen - @yro854
Representative histological sections (H&E staining) showing various microspheres within the vessels of the kidney: (a) EZ 40; (b) EZ 100; (c) LUMI 40–90; (d) LUMI 70–150; (LC 70–150). Scale bar = 50 µm.
Sagittal gadolinium enhanced MRI of the pelvis 3 months following uterine artery embolization demonstrates a smaller (4cm) nonenhancing (avascular) fibroid (arrow) and a uterus which has decreased in size (10cm x 5cm x 6cm).
Bronchial artery embolization by tris-acryl gelatin microspheres to embolize a hypervascular (bleeding) mass. It is a solitary fibrous tumor. The embolic material is occluding arteries.
These microspheres range from 0.16 - 0.65 mm in diameter with a mean diameter of 0.43 mm. With H&E staining this material has a distinctive, strong resemblance to thyroid colloid.
Images contributed by Dr. Sanjay Mukhopadhyay - @smlungpathguy
These microspheres were found in the gallbladder of a patient who underwent transarterial chemoembolization (TACE) for treatment of hepatocellular carcinoma. They may induce fibrosis and a foreign body giant cell reaction.
Images contributed by Dr. Zhao Chang - @zhaochang001
Hemoptysis in a patient with cystic fibrosis.
Bronchial artery embolization by tris-acryl gelatin microspheres is sometimes used to manage this complication. Easier to see the embolic material than the occluded artery.
These microspheres range from 0.16 - 0.65 mm in diameter with a mean diameter of 0.43 mm. With H&E staining this material has a distinctive, strong resemblance to thyroid colloid.
Images contributed by Dr. Sanjay Mukhopadhyay - @smlungpathguy
Intravascular embolized microcrystalline cellulose with a foreign body giant cell reaction. Microcrystalline cellulose is used as a filler in pharmaceutical tablets. It embolizes to the lungs when aqueous suspensions of pulverized tablets are injected intravenously.
Image contributed by Dr. Yale Rosen - @yro854
Incidental finding in an excisional biopsy showing organizing pneumonia. This mucin-like material is located in the interstitium immediately adjacent to pulmonary capillaries. It seems likely that this material embolized to capillaries and then diffused to its extravascular location.
Images contributed by Dr. Frank Huang
Please enter a comment if you know what this material is.
Foreign material of undetermined type is present within blood vessels and lung parenchyma within an abscess. It seems likely that these are septic emboli, possibly originating from an IV solution. The abscess is likely the result of septic embolization.
Images contributed by Dr. Celina Stayerman - @ariella8
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Paras Hospitals | Paras Healthcare | Paras Panchkula
Doctor's Informative Video on Acute Stroke Management by Dr. (Prof.) Vivek Gupta, Sr. consultant and Head- Interventional Neuroradiology, Paras Hospitals Panchkula.
Know more about Dr. Vivek Gupta here- ow.ly/Rczs50ufJUk
Profile- Dr. (Prof.) Vivek Gupta is a leading Interventional Neuroradiologist of the country. He has rich experience of more than 15 years in diagnosing and managing Neuro-vascular conditions like Cerebral Aneurysms, Arterio-Venous Malformations, Acute Stroke, Carotid Stenosis, etc.
Previously he was Professor and in-charge of Interventional Neuroradiology at PGIMER Chandigarh. He was instrumental in initiation and development of the Neurointervention section at PGIMER Chandigarh where he worked for more than 14 years. He has been the first one in this region to start several new techniques in the field of minimally invasive treatment of cerebral aneurysms and acute stroke including Flow Diversion for Cerebral Aneurysms. He is among the very few specialists in the country who is doing intra-arterial chemotherapy /embolizations in children less than 1 year of age.
He has also pioneered research in the field of stem cell therapy in acute stroke which has been published in reputed American journals. He has treated hundreds of patient with various vascular malformations of head and neck.
Microscopic photo showing cluster of embolized uterine arteries in myometrium. The arteries are embolized by polyvinyl alcohol (PVA) particles. H & E stain. 20X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA. (乔建华医学博士， 美国病理学家学院专家会员。美国加州洛杉矶)
Microscopic photo showing infarcted leiomyoma and adjacent cluster of embolized uterine arteries (right portion of the photo). The arteries are embolized by polyvinyl alcohol (PVA) particles. . H & E stain. 10X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA. (乔建华医学博士， 美国病理学家学院专家会员。美国加州洛杉矶)
Microscopic photo showing infarcted leiomyoma and adjacent cluster of embolized uterine arteries (left portion of the photo). The arteries are embolized by polyvinyl alcohol (PVA) particles. H & E stain. 10X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA. (乔建华医学博士， 美国病理学家学院专家会员。美国加州洛杉矶)
Microscopic photo showing infarcted leiomyoma and adjacent uninvolved myometrium (upper portion of the photo). H & E stain. 10X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA. (乔建华医学博士， 美国病理学家学院专家会员。美国加州洛杉矶)
Neursurgeon Fernando Gonzalez, MD, and a team of neurointerventionalists at the Jefferson Hospital for Neuroscience of Thomas Jefferson University Hospitals treat Belinda Cook of Philadelphia with the newly approved Pipeline Embolization Device for four brain aneurysms.
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Team Members
Jacob Bjorn, Ethan Holley, William Weiner, Alyssa Hartman, Laura Lynch, and Rachel Morrison, Biomedical Engineering
Advisor
Jingfeng Jiang, Biomedical Engineering
Sponsor
Boston Scientific
Project Overview
Boston Scientific tasked our team with designing, building, and testing a fixation mechanism for a leadless pacing device. This wireless pacemaker is to be attached on the interior endocardial surface of the right ventricle of the heart. The
mechanism must stay fixated without risking device detachment, which could cause embolization and pulmonary infarction, and it must be removable at
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The most beautiful women in TV and Movie History now become Barbie Collector Dolls created by acclaimed re-paint Artist Donna Brinkley.
Farrah Leni Fawcett is known as the world's Sexiest Star of all time... she will forever be one of Hollywood's greatest Icons. She was born in Corpus Christi, Texas, the younger of two daughters.[3] Her mother, Pauline Alice January 30, 1914 – March 4, 2005), was a homemaker, and her father, James William Fawcett (October 14, 1917 – August 23, 2010), was an oil field contractor. Her sister was Diane Fawcett Walls (October 27, 1938 – October 16, 2001), a graphic artist. She was of Irish, French, English, and Choctaw Native American ancestry. Fawcett once said the name Ferrah was made up by her mother because it went well with their last name.
A Roman Catholic, Fawcett's early education was at the parish school of the church her family attended, St. Patrick's Roman Catholic Church in Corpus Christi. She graduated from W. B. Ray High School in Corpus Christi, where she was voted Most Beautiful by her classmates her Freshman, Sophomore, Junior and Senior years of High School. For three years, 1965–68, Fawcett attended the University of Texas at Austin, living one semester in Jester Center, and she became a sister of Delta Delta Delta Sorority. During her Freshman year, she was named one of the Ten Most Beautiful Coeds on Campus, the first time a Freshman had been chosen. Their photos were sent to various agencies in Hollywood. David Mirsch, a Hollywood agent called her and urged her to come to Los Angeles. She turned him down but he called her for the next two years. Finally, in 1968, the summer following her junior year, with her parents' permission to try her luck in Hollywood, Farrah moved to Hollywood. She did not return.
Upon arriving in Hollywood in 1968 she was signed to a $350 a week contract with Screen Gems. She began to appear in commercials for UltraBrite toothpaste, Noxema, Max Factor, Wella Balsam shampoo and conditioner, Mercury Cougar automobiles and Beauty Rest matresses. Fawcett's earliest acting appearances were guest spots on The Flying Nun and I Dream of Jeannie. She made numerous other TV appearances including Owen Marshall: Counselor at Law, [Mayberry RFD]] and The Partridge Family. She appeared in four episodes of The Six Million Dollar Man with husband Lee Majors, The Dating Game, S.W.A.T and a recurring role on Harry O alongside David Janssen. She also appeared in the Made for TV movies, The Feminist and the Fuzz, The Great American Beauty Contest, The Girl Who Came Giftwrapped, and Murder of Flight 502.
She had a sizable part in the 1969 French romantic-drama, Love Is a Funny Thing. She played opposite Raquel Welch and Mae West in the film version of, Myra Breckinridge (1970). The film earned negative reviews and was a box office flop. However, much has been written and said about the scene where Farrah and Raquel share a bed, and a near sexual experience. Fawcett co-starred with Michael York and Richard Jordan in the well-received science-fiction film, Logan's Run in 1976.
In 1976, Pro Arts Inc., pitched the idea of a poster of Fawcett to her agent, and a photo shoot was arranged with photographer Bruce McBroom, who was hired by the poster company. According to friend Nels Van Patten, Fawcett styled her own hair and did her make-up without the aid of a mirror. Her blonde highlights were further heightened by a squeeze of lemon juice. From 40 rolls of film, Fawcett herself selected her six favorite pictures, eventually narrowing her choice to the one that made her famous. The resulting poster, of Fawcett in a one-piece red bathing suit, was a best-seller; sales estimates ranged from over 5 million[12] to 8 million to as high as 12 million copies.
On March 21, 1976, the first appearance of Fawcett playing the character Jill Munroe in Charlie's Angels was aired as a movie of the week. Fawcett and her husband were frequent tennis partners of producer Aaron Spelling, and he and his producing partner thought of casting Fawcett as the golden girl Jill because of his friendship with the couple. The movie starred Kate Jackson, Jaclyn Smith and Fawcett (then billed as Farrah Fawcett-Majors) as private investigators for Townsend Associates, a detective agency run by a reclusive multi-millionaire whom the women had never met. Voiced by John Forsythe, the Charles Townsend character presented cases and dispensed advice via a speakerphone to his core team of three female employees, whom he referred to as Angels. They were aided in the office and occasionally in the field by two male associates, played by character actors David Doyle and David Ogden Stiers. The program quickly earned a huge following, leading the network to air it a second time and approve production for a series, with the pilot's principal cast except David Ogden Stiers.
Fawcett's record-breaking poster that sold 12 million copies.
The Charlie's Angels series formally debuted on September 22, 1976. Fawcett emerged as a fan favorite in the show, and the actress won a People's Choice Award for Favorite Performer in a New TV Program. In a 1977 interview with TV Guide, Fawcett said: When the show was number three, I thought it was our acting. When we got to be number one, I decided it could only be because none of us wears a bra.
Fawcett's appearance in the television show boosted sales of her poster, and she earned far more in royalties from poster sales than from her salary for appearing in Charlie's Angels. Her hairstyle went on to become an international trend, with women sporting a Farrah-do a Farrah-flip, or simply Farrah hair Iterations of her hair style predominated American women's hair styles well into the 1980s.
Fawcett left Charlie's Angels after only one season and Cheryl Ladd replaced her on the show, portraying Jill Munroe's younger sister Kris Munroe. Numerous explanations for Fawcett's precipitous withdrawal from the show were offered over the years. The strain on her marriage due to her long absences most days due to filming, as her then-husband Lee Majors was star of an established television show himself, was frequently cited, but Fawcett's ambitions to broaden her acting abilities with opportunities in films have also been given. Fawcett never officially signed her series contract with Spelling due to protracted negotiations over royalties from her image's use in peripheral products, which led to an even more protracted lawsuit filed by Spelling and his company when she quit the show.
The show was a major success throughout the world, maintaining its appeal in syndication, spawning a cottage industry of peripheral products, particularly in the show's first three seasons, including several series of bubble gum cards, two sets of fashion dolls, numerous posters, puzzles, and school supplies, novelizations of episodes, toy vans, and a board game, all featuring Fawcett's likeness. The Angels also appeared on the covers of magazines around the world, from countless fan magazines to TV Guide (four times) to Time Magazine.
The series ultimately ran for five seasons. As part of a settlement to a lawsuit over her early departure, Fawcett returned for six guest appearances over seasons three and four of the series.
In 2004, the television movie Behind the Camera: The Unauthorized Story of Charlie's Angels dramatized the events from the show with supermodel and actress Tricia Helfer portraying Fawcett and Ben Browder portraying Lee Majors, Fawcett's then-husband.
In 1983, Fawcett won critical acclaim for her role in the Off-Broadway stage production of the controversial play Extremities, written by William Mastrosimone. Replacing Susan Sarandon, she was a would-be rape victim who turns the tables on her attacker. She described the role as the most grueling, the most intense, the most physically demanding and emotionally exhausting of her career. During one performance, a stalker in the audience disrupted the show by asking Fawcett if she had received the photos and letters he had mailed her. Police removed the man and were able only to issue a summons for disorderly conduct.
The following year, her role as a battered wife in the fact-based television movie The Burning Bed (1984) earned her the first of her four Emmy Award nominations. The project is noted as being the first television movie to provide a nationwide 800 number that offered help for others in the situation, in this case victims of domestic abuse. It was the highest-rated television movie of the season.
In 1986, Fawcett appeared in the movie version of Extremities, which was also well received by critics, and for which she received a Golden Globe nomination for Best Performance by an Actress in a Motion Picture – Drama.
She appeared in Jon Avnet's Between Two Women with Colleen Dewhurst, and took several more dramatic roles as infamous or renowned women. She was nominated for Golden Globe awards for roles as Beate Klarsfeld in Nazi Hunter: The Beate Klarsfeld Story and troubled Woolworth heiress Barbara Hutton in Poor Little Rich Girl: The Barbara Hutton Story, and won a CableACE Award for her 1989 portrayal of groundbreaking LIFE magazine photojournalist Margaret Bourke-White in Double Exposure: The Story of Margaret Bourke-White. Her 1989 portrayal of convicted murderer Diane Downs in the miniseries Small Sacrifices earned her a second Emmy nomination[20] and her sixth Golden Globe Award nomination. The miniseries won a Peabody Award for excellence in television, with Fawcett's performance singled out by the organization, which stated Ms. Fawcett brings a sense of realism rarely seen in television miniseries (to) a drama of unusual power Art meets life.
Fawcett, who had steadfastly resisted appearing nude in magazines throughout the 1970s and 1980s (although she appeared topless in the 1980 film Saturn 3), caused a major stir by posing semi-nude in the December 1995 issue of Playboy.[citation needed] At the age of 50, she returned to Playboy with a pictorial for the July 1997 issue, which also became a top seller. The issue and its accompanying video featured Fawcett painting on canvas using her body, which had been an ambition of hers for years.
That same year, Fawcett was chosen by Robert Duvall to play his wife in an independent feature film he was producing, The Apostle. Fawcett received an Independent Spirit Award nomination as Best Actress for the film, which was highly critically acclaimed.
In 2000, she worked with director Robert Altman and an all-star cast in the feature film Dr. T the Women, playing the wife of Richard Gere (her character has a mental breakdown, leading to her first fully nude appearance). Also that year, Fawcett's collaboration with sculptor Keith Edmier was exhibited at the Los Angeles County Museum of Art, later traveling to The Andy Warhol Museum. The sculpture was also presented in a series of photographs and a book by Rizzoli.
In November 2003, Fawcett prepared for her return to Broadway in a production of Bobbi Boland, the tragicomic tale of a former Miss Florida. However, the show never officially opened, closing before preview performances. Fawcett was described as vibrating with frustration at the producer's extraordinary decision to cancel the production. Only days earlier the same producer closed an Off-Broadway show she had been backing.
Fawcett continued to work in television, with well-regarded appearances in made-for-television movies and on popular television series including Ally McBeal and four episodes each of Spin City and The Guardian, her work on the latter show earning her a third Emmy nomination in 2004.
Fawcett was married to Lee Majors, star of television's The Six Million Dollar Man, from 1973 to 1982, although the couple separated in 1979. During her marriage, she was known and credited in her roles as Farrah Fawcett-Majors.
From 1979 until 1997 Fawcett was involved romantically with actor Ryan O'Neal. The relationship produced a son, Redmond James Fawcett O'Neal, born January 30, 1985 in Los Angeles.[26] In April 2009, on probation for driving under the influence, Redmond was arrested for possession of narcotics while Fawcett was in the hospital.[citation needed] On June 22, 2009, The Los Angeles Times and Reuters reported that Ryan O'Neal had said that Fawcett had agreed to marry him as soon as she felt strong enough.
From 1997 to 1998, Fawcett had a relationship with Canadian filmmaker James Orr, writer and producer of the Disney feature film in which she co-starred with Chevy Chase and Jonathan Taylor Thomas, Man of the House. The relationship ended when Orr was charged with and later convicted of beating Fawcett during a 1998 fight between the two.
On June 5, 1997, Fawcett received negative commentary after giving a rambling interview and appearing distracted on Late Show with David Letterman. Months later, she told the host of The Howard Stern Show her behavior was just her way of joking around with the television host, partly in the guise of promoting her Playboy pictoral and video, explaining what appeared to be random looks across the theater was just her looking and reacting to fans in the audience. Though the Letterman appearance spawned speculation and several jokes at her expense, she returned to the show a week later, with success, and several years later, after Joaquin Phoenix's mumbling act on a February 2009 appearance on The Late Show, Letterman wrapped up the interview by saying, I'm sorry you couldn't be here tonight and recalled Fawcett's earlier appearance by noting we owe an apology to Farrah Fawcett.
Fawcett's elder sister, Diane Fawcett Walls, died from lung cancer just before her 63rd birthday, on October 16, 2001.[33] The fifth episode of her 2005 Chasing Farrah series followed the actress home to Texas to visit with her father, James, and mother, Pauline. Pauline Fawcett died soon after, on March 4, 2005, at the age of 91.
Fawcett was diagnosed with anal cancer in 2006, and began treatment, including chemotherapy and surgery. Four months later, on her 60th birthday, the Associated Press wire service reported that Fawcett was, at that point, cancer free.
Less than four months later, in May 2007, Fawcett brought a small digital video camera to document a doctor's office visit. There, she was told a malignant polyp was found where she had been treated for the initial cancer. Doctors contemplated whether to implant a radiation seeder (which differs from conventional radiation and is used to treat other types of cancer). Fawcett's U.S. doctors told her that she would require a colostomy. Instead, Fawcett traveled to Germany for treatments described variously in the press as holistic aggressive and alternative. There, Dr. Ursula Jacob prescribed a treatment including surgery to remove the anal tumor, and a course of perfusion and embolization for her liver cancer by Doctors Claus Kiehling and Thomas Vogl in Germany, and chemotherapy back in Fawcett's home town of Los Angeles. Although initially the tumors were regressing, their reappearance a few months later necessitated a new course, this time including laser ablation therapy and chemoembolization. Aided by friend Alana Stewart, Fawcett documented her battle with the disease.
In early April 2009, Fawcett, back in the United States, was hospitalized, with media reports declaring her unconscious and in critical condition, although subsequent reports indicated her condition was not so dire. On April 6, the Associated Press reported that her cancer had metastasized to her liver, a development Fawcett had learned of in May 2007 and which her subsequent treatments in Germany had targeted. The report denied that she was unconscious, and explained that the hospitalization was due not to her cancer but a painful abdominal hematoma that had been the result of a minor procedure. Her spokesperson emphasized she was not at death's door adding - She remains in good spirits with her usual sense of humor ... She's been in great shape her whole life and has an incredible resolve and an incredible resilience. Fawcett was released from the hospital on April 9, picked up by longtime companion O'Neal, and, according to her doctor, was walking and in great spirits and looking forward to celebrating Easter at home.
A month later, on May 7, Fawcett was reported as critically ill, with Ryan O'Neal quoted as saying she now spends her days at home, on an IV, often asleep. The Los Angeles Times reported Fawcett was in the last stages of her cancer and had the chance to see her son Redmond in April 2009, although shackled and under supervision, as he was then incarcerated. Her 91-year-old father, James Fawcett, flew out to Los Angeles to visit.
The cancer specialist that was treating Fawcett in L.A., Dr. Lawrence Piro, and Fawcett's friend and Angels co-star Kate Jackson – a breast cancer survivor – appeared together on The Today Show dispelling tabloid-fueled rumors, including suggestions Fawcett had ever been in a coma, had ever reached 86 pounds, and had ever given up her fight against the disease or lost the will to live. Jackson decried such fabrications, saying they really do hurt a human being and a person like Farrah. Piro recalled when it became necessary for Fawcett to undergo treatments that would cause her to lose her hair, acknowledging Farrah probably has the most famous hair in the world but also that it is not a trivial matter for any cancer patient, whose hair affects [one's] whole sense of who [they] are. Of the documentary, Jackson averred Fawcett didn't do this to show that 'she' is unique, she did it to show that we are all unique ... This was ... meant to be a gift to others to help and inspire them.
The two-hour documentary Farrah's Story, which was filmed by Fawcett and friend Alana Stewart, aired on NBC on May 15, 2009.[47] The documentary was watched by nearly nine million people at its premiere airing, and it was re-aired on the broadcast network's cable stations MSNBC, Bravo and Oxygen. Fawcett earned her fourth Emmy nomination posthumously on July 16, 2009, as producer of Farrah's Story.
Controversy surrounded the aired version of the documentary, with her initial producing partner, who had worked with her four years earlier on her reality series Chasing Farrah, alleging O'Neal's and Stewart's editing of the program was not in keeping with Fawcett's wishes to more thoroughly explore rare types of cancers such as her own and alternative methods of treatment. He was especially critical of scenes showing Fawcett's son visiting her for the last time, in shackles, while she was nearly unconscious in bed. Fawcett had generally kept her son out of the media, and his appearances were minimal in Chasing Farrah.
Fawcett died at approximately 9:28 am, PDT on June 25, 2009, in the intensive care unit of Saint John's Health Center in Santa Monica, California, with O'Neal and Stewart by her side. A private funeral was held in Los Angeles on June 30. Fawcett's son Redmond was permitted to leave his California detention center to attend his mother's funeral, where he gave the first reading.
The night of her death, ABC aired an hour-long special episode of 20/20 featuring clips from several of Barbara Walters' past interviews with Fawcett as well as new interviews with Ryan O'Neal, Jaclyn Smith, Alana Stewart, and Dr. Lawrence Piro. Walters followed up on the story on Friday's episode of 20/20. CNN's Larry King Live planned a show exclusively about Fawcett that evening until the death of Michael Jackson several hours later caused the program to shift to cover both stories. Cher, a longtime friend of Fawcett, and Suzanne de Passe, executive producer of Fawcett's Small Sacrifices mini-series, both paid tribute to Fawcett on the program. NBC aired a Dateline NBC special Farrah Fawcett: The Life and Death of an Angel; the following evening, June 26, preceded by a rebroadcast of Farrah's Story in prime time. That weekend and the following week, television tributes continued. MSNBC aired back-to-back episodes of its Headliners and Legends episodes featuring Fawcett and Jackson. TV Land aired a mini-marathon of Charlie's Angels and Chasing Farrah episodes. E! aired Michael and Farrah: Lost Icons and the The Biography Channel aired Bio Remembers: Farrah Fawcett. The documentary Farrah's Story re-aired on the Oxygen Network and MSNBC.
Larry King said of the Fawcett phenomenon,
TV had much more impact back in the '70s than it does today. Charlie's Angels got huge numbers every week – nothing really dominates the television landscape like that today. Maybe American Idol comes close, but now there are so many channels and so many more shows it's hard for anything to get the audience, or amount of attention, that Charlie's Angels got. Farrah was a major TV star when the medium was clearly dominant.
Playboy founder Hugh Hefner said Farrah was one of the iconic beauties of our time. Her girl-next-door charm combined with stunning looks made her a star on film, TV and the printed page.
Kate Jackson said,
She was a selfless person who loved her family and friends with all her heart, and what a big heart it was. Farrah showed immense courage and grace throughout her illness and was an inspiration to those around her... I will remember her kindness, her cutting dry wit and, of course, her beautiful smile...when you think of Farrah, remember her smiling because that is exactly how she wanted to be remembered: smiling.
She is buried at the Westwood Village Memorial Park in Los Angeles.
The red one-piece bathing suit worn by Farrah in her famous 1976 poster was donated to the Smithsonian's National Museum of American History (NMAH) on February 2, 2011.[65] Said to have been purchased at a Saks Fifth Avenue store, the red Lycra suit made by the leading Australian swimsuit company Speedo, was donated to the Smithsonian by her executors and was formally presented to NMAH in Washington D.C. by her longtime companion Ryan O'Neal.[66] The suit and the poster are expected to go on temporary display sometime in 2011–12. They will be made additions to the Smithsonian's popular culture department.
The famous poster of Farrah in a red swimsuit has been produced as a Barbie doll. The limited edition dolls, complete with a gold chain and the girl-next-door locks, have been snapped up by Barbie fans.
In 2011, Men's Health named her one of the 100 Hottest Women of All-Time ranking her at No. 31
Neursurgeon Fernando Gonzalez, MD, and a team of neurointerventionalists at the Jefferson Hospital for Neuroscience of Thomas Jefferson University Hospitals treat Belinda Cook of Philadelphia with the newly approved Pipeline Embolization Device for four brain aneurysms.
Neursurgeon Fernando Gonzalez, MD, of the Jefferson Hospital for Neuroscience examines Belinda Cook of Philadelphia who he treated with the newly approved Pipeline Embolization Device for four brain aneurysms.
Neursurgeon Fernando Gonzalez, MD, and a team of neurointerventionalists at the Jefferson Hospital for Neuroscience of Thomas Jefferson University Hospitals treated Belinda Cook of Philadelphia with the newly approved Pipeline Embolization Device for four brain aneurysms. Four months after she was treated the aneurysms had disappeared from her angiogram.
Cancer microsphere intervention (CMI) means a strategy of transarterial infusion of microspheres into tumor.Transarterial chemoembolization (TACE) is a most used option of CMI. TACE is a form of intra-arterial catheter-based chemotherapy that selectively delivers high doses of cytotoxic drug to the tumor bed combining with the effect of ischemic necrosis induced by arterial embolization.
Neursurgeon Fernando Gonzalez, MD, and a team of neurointerventionalists at the Jefferson Hospital for Neuroscience of Thomas Jefferson University Hospitals treat Belinda Cook of Philadelphia with the newly approved Pipeline Embolization Device for four brain aneurysms.
Neursurgeon Fernando Gonzalez, MD, and a team of neurointerventionalists at the Jefferson Hospital for Neuroscience of Thomas Jefferson University Hospitals treat Belinda Cook of Philadelphia with the newly approved Pipeline Embolization Device for four brain aneurysms.
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Vascular problems such varicose veins, spider veins and a lesser-known condition called pelvic congestion syndrome (PCS) affect approximately one-third of the American population. Varicose veins are the most well known of these vascular problems, but spider veins, those thin, wispy veins found sometimes on the face, but mostly on legs and feet, can also cause problems.
PCS is essentially varicose veins located in the pelvic area that can produce severe pain. If you had a parent who had one of these conditions, you have a 90% chance too of developing vein problems.
Are They Varicose Veins or Spider Veins?
Varicose veins and spider veins afflict both men and women, although twice as many females as males are affected. Both types of veins have a twisted appearance, therefore making it difficult for the average person to determine which condition they have. Spider veins are generally smaller in appearance and provide more of a cosmetic problem than varicose veins that can appear ropelike and bulge outward from the skin as they grow. That’s why it’s important to have a medical professional thoroughly examine the affected area and recommend possible treatments.
How Vein Health Relates to Other Conditions
Varicose veins can lead to legs feeling heavy, tired and swollen at the end of the day. Obviously this can put severe limits on your lifestyle.
Although some spider veins never progress beyond a cosmetic problem, they can be early warning signs of other issues such as venous insufficiency. Vein problems can eventually become limb threatening if allowed to progress for too long. The problems you can experience from spider or varicose veins include the following.
Blood Clots
Blood clots can form if you had recent surgery, a long flight or car ride, or if you had a major injury affecting your ability to walk. Clots that reach the heart or lungs can have consequences that severely alter your quality of life and involve life-long health issues. If the blood clots break off and travel to the lungs, it’s called a pulmonary embolism. This is a life-threatening condition.
Thrombophlebitis happens when blood clots excessively in a varicose vein, which hardens and becomes warm and painful to the touch. Deep vein thrombosis develops deep inside the leg, causing swelling and pain.
Ulcers
Ulcers can result in patients who have varicose veins. The constant pressure and tension with leg veins sets the stage for further changes that include swelling and inflammation. These conditions eventually lead to leg ulcers. Varicose veins that have existed for years affect the body’s ability to heal. Statistics indicate that varicose veins are responsible for 80% of leg ulcers as these diseased veins adversely affect the body’s ability to heal.
Cellulitis
Possible skin issues may develop after spider veins appear. One of these is cellulitis, a condition that develops when bacteria is naturally present on the skin starts growing aggressively. Although it often starts with what seems a minor condition, cellulitis can lead to tissue and organ damage, as well as ongoing infections that prevent the body from complete healing.
VIVAA Can Help Relieve Vein Problems
Kirkland area residents can partake in a variety of treatment options to help relieve your vascular issues. Our professional staff will monitor your spider or varicose veins, recommend preventive measures that you can take, along with appropriate treatment to remove spider or varicose veins.
For spider veins we offer:
Laser treatment
Sclerotherapy
Ultrasound-guided sclerotherapy
For varicose veins, we recommend a minimally invasive procedure called Venefit, also known as endovenous ablation. This treatment, which involves little downtime, utilizes radio frequency to cauterize and close your varicose veins. It’s performed under local anesthesia that uses a catheter inserted into a vein and guided by ultrasound to the correct location. Affected veins are treated within a matter of minutes. After the procedure only a small bandage and compression stockings are needed.
Treatment for PCS is also minimally invasive. We offer pelvic ultrasounds for proper diagnosis and pelvic vein embolization that closes affected veins, rendering them harmless.
Don’t suffer another day with ugly veins and/or pain. VIVAA is here to help. Contact us at 425-250-9999 to schedule a consultation and to find out more about our cutting-edge vascular treatments.
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