3+ months healed. Yep, the linework =/= great. Whatever.

You will not notice this tattoo in normal light. There is a faint scar of the tattoo visible and when pointed out to people they said they had a hard time seeing it even when shown. It does glow brightly under blacklight.

 

Information Regarding UV Tattoos

Chameleon UV Tattoo Ink: I purchased 1oz Titanium White UV ink from this vendor. Click here for the Material Data Safety Sheets regarding BIOMETRIX System-1000 Photonic Marking Formulation Safe Spectral Marking Pigment inks.

According to the website, "The Crazy Chameleon has on file a letter dated April 3, 1995 from the Division of Programs and Enforcement Policy, USFDA, and addressed the manufacturer of our ink, containing the following conclusion:

'Having reviewed the information supplied by you [our manufacturer of the ink] and your supplier ... FDA would have no objection to the use of your photonic dye marking [tattooing] system ...'"

I had this tattoo done at No Regrets Tattoo in Raleigh, NC. They were the only shop in the state that would work with the UV ink.

 

Information I gathered at the time about UV tattoos left me with the impression that many tattoo artist professionals will not ink with them. They are relatively new to the market (I've heard only used in tattoos for the last 11 years) and their safety and long-term effectiveness is untested. Do your research and ask a health care provider if you have any questions related to the medical safety of such tattoos.

The most stunning medical quote ever made by a Harvard professor:

"The FDA protects the big drug companies, and is subsequently rewarded, and using the government's police powers. they attack those who threaten the drug companies. The thing that bugs me is that people think that the FDA is protecting them. It isn't. What the FDA is doing, and what the public thinks it is doing are as different as night and day."

~Dr. Herbert Ley, Former Commissioner of the USFDA

AFRICA -Dr.C.K.Atal, United Nations consultant - Africa,1993

 

INTERNATIONAL CONTRIBUTIONS

41.INTERNATIONAL BASE – He has resided in USA (1954 to 1958) as a US resident (status green card), worked as Chairman/associate Professor grade at Nebraska, USA, and migrated to Indian citizenship, going against the trend of brain drain. He has worked for about 8 -9 years internationally as UN consultant (including 7 years in field south East Asia, base Vietnam, 1985 - 92). He has extensively travelled to 30-35 countries internationally as UN consultant, as CSIR consultant or mission consultant to major organizations in countries in Asia, SE Asia, Europe, USA, Africa etc.

42.INTERNATIONAL CONSULTANCIES-(Serial no 43-65, MISSION CONSULTANT to world organizations, also See countries traveled Serial no 68). The various scientific interactions are for Eli Lilly-USA, Polish Academy of Sciences, British Council, Organization Of African Unity (OAU), West Indies, Burma Government, Vietnam Government, Bangladesh Government, Pan American Health Organization (PAHO), USFDA, Soviet Academy of Sciences, University of Texas, USA (lecture at Pharmaceutical Sciences department), UK University of Exeter (Commonwealth Foundation, Univ. Grants Commission), University of Munchen, Germany, SAARC scientific conference (Sri Lanka), France, Bulgaria etc.

43.UNITED NATIONS INTERNATIONAL CONSULTANCIES- See details in mission consultant, UN Passport records (laissez passer).

A.WHO (Bangladesh), WHO (USA), FAO (non wood forest products), APPOINTED/SELECTED FOR UN PROJECT IN AFGHANISTAN (project postponed for technical/safety reasons due to instability in the region), UN HEADQUARTERS (VIENNA, AUSTRIA) for formulating UN projects in Vietnam,UNITED NATIONS -AFRICA (for identifying viable projects in Africa),

B.UNDP, UNIDO-VIETNAM - five United Nations projects costing approximately about 10 to 13 million US dollars.

•HERBAL-MEDICINES.

•ESSENTIAL-OILS.

•DYES-&-PIGMENTS.

•AROMA-CHEMICALS.

•HIGH VALUE ROSIN & TURPENTINE.

MISSION CONSULTANT TO MAJOR INTERNATIONAL WORLD ORGANISATIONS

CONSULTANCY, ADVISOR, PROJECT LEADER, IDENTIFYING AND IMPLEMENTING PROJECTS, TECHNOLOGY DEMONSTRATION, SCIENTIFIC INTERACTION, FELLOWSHIP, LECTURES, CHAIRING INTERNATIONAL CONFERENCES ETC

44.USA (1957-58,) - ELI LILLY SUMMER FELLOWSHIP, USA - on selection & development of high yield strains of Clavicaps purpurea and submerged culture of Clavicaps purpurea .Other visits in 1974, 1981, 1992, 2004.

45.USA,National science foundation,1974-two months

46.POLAND (Nov,1972) – POLISH ACADEMY OF SCIENCES/ INSTITUTE OF ORGANIC CHEMISTRY - headed by the Polish Director, Dr. Kocor (pronounced as kochur) invited Dr. Atal for lecture (Chemistry of Natural Products) & technology demonstration in several institutes of Poland in 1972. www.flickr.com/photos/13059662@N06/6506006811/

47.WEST INDIES- CARRIBEAN AREA (1979) - (expert on behalf of COMMON WEALTH RESEARCH COUNCIL-BRITISH COUNCIL, TRINIDAD TOBAGO)-, Distillation techniques & technology demonstration, lectures, introduction of lemon grass oils etc.

48.GERMANY (UNIVERSITY OF MUNCHEN /MUNICH)-(Nuclear research institute) invited Dr. Atal as a solar energy consultant, visited Germany in 1978 & 1985.

49.FRANCE (1980) - STRASBOURG INTERNATIONAL RESEARCH CONGRESS -to chair the international conference “International Research Congress on natural products as medicinal agents”, on July, 6-12, 1980.

50.BULGARIA (1981) - SOFIA INTERNATIONAL CONFERENCE, -to chair a session on the international conference on “Chemistry and Biotechnology of biologically active natural products” and Rose oil, on 22 Sept, 1981.

51.GREECE-delivered a special lecture at international symposium on Aromatic plants.

52.BURMA (1981) – GOVERNMENT OF BURMA (Rangoon), (presently Myanmar): To set up Menthol distillation plant , transfer of technology for production of bold crystals of Menthol from Mentha arvensis, setting up a menthol pilot plant & demonstration unit (Menthol extraction plant) and training techniques. The Pharmaceutical research Department of Central Research Organization (CRO), Burma was provided Diosgenin – Progesteron plant at Hmaw-Bi, Rangoon. www.flickr.com/photos/13059662@N06/6824106944/in/photostr... www.flickr.com/photos/13059662@N06/6970421821/in/photostream

53.USA (Oct 1981) FOUR WEEKS –He was appointed as international consultant to USA in his capacity as one of the leading world authorities on Crotalaria.

A.WHO (WORLD HEALTH ORGANISATION)- World Health Organization was the primary agency to appoint him as WHO expert consultant on toxicology, particularly on Crotalaria and its toxicity and sent him to USA as consultant to other agencies.

B.USFDA (BUREAU OF FOODS, US FOOD & DRUG ADMINISTRATION) – USFDA-Division Of Toxicology as consultant on toxicology, for division of chemistry and physics, & division of toxicology, bureau of foods, USFDA , regarding toxicity studies / human toxicity particularly by Crotalaria mixed in food chain/ Pyrrolizidine alkaloid containing seeds.

C.PAHO (PAN AMERICAN HEALTH ORGANIZATION) - WHO appointed him as consultant on toxicology for PAHO as well as USFDA simultaneously.

54.RUSSIA AND TASHKENT, (1981) - Soviet academy of sciences: invited Dr. Atal for lecture and technology demonstration.

55.WORLD HEALTH ORGANISATION

A.USA CONSULTANCY - as noted above.

B.BANGLADESH CSIR- as noted below.

56.SELECTED FOR UN PROJECT IN AFGHANISTAN (around 1983-84) –due to prevailing instability, project was suspended/postponed for safety reasons.

57.BANGLADESH GOVERNMENT (1984) - for helping Bangladesh CSIR, for technology demonstration to upgrade/modernize their Pharmaceutical formulations, like Chavanprash. (See NEXT HEADING-WHO below).

58.WORLD HEALTH ORGANIZATION (WHO) 1984 – (Refer to Bangladesh Govt. Above) appointed him as consultant to help establish technology institutes for Bangladesh Govt. (CSIR). (See above topic).

59.UNITED KINGDOM (1984) -University of Exeter (Commonwealth Foundation / University Grants Commission) invited Dr. Atal for lecture tours. A Holland tour also was included in this tour.

60.UNITED NATIONS (VIENNA, AUSTRIA) (1984 /85) for identifying projects in developing countries like South East Asia, Vietnam. Project was handled by Mrs. Cheknovorian who offered Dr. Atal to implement these projects in Vietnam as UN chief consultant and which was soon accepted by Dr. Atal.

61.UNIDO/UNDP,VIETNAM ( BASE S. E. ASIA - seven years, 1985-1992)- For peer reviews on UN contributions by a distinguished international UN consultant, www.flickr.com/photos/13059662@N06/5737077185/in/photostream Dr. Atal was Chief technical advisor (Chemical Technologist in UN roster) for five projects funded by United Nations costing about 11-13 million US dollars implemented and commissioned in Vietnam ( field area South East Asia). He implemented the projects successfully, on time schedule and within budget.

•PROJECT-DP/VIE/80/032-HANOI-VIETNAM,(HERBAL-MEDICINES).

•PROJECT-DP/VIE/84/010-HANOI-VIETNAM,(ESSENTIAL-OILS).

•PROJECT-DP/VIE/85/001-HO CHI MINH CITY-VIETNAM(DYES & PIGMENTS).

•PROJECT-DP/VIE/86/033-HO CHI MINH CITY - VIETNAM(AROMA CHEMICALS).

•PROJECT-DP/VIE/TECHNOLOGY FOR HIGH VALUE ROSIN & TURPENTINE. This resulted in high quality production of several natural plant based products, with huge socioeconomic and industrial benefit. The projects were successful socioeconomically. For example, in the very first year of its production, the sales of Eucalyptus oil crossed the million dollar mark in international market due to its strict quality control. Other examples include Bixa orellana (butter yellow) Berberine factories, Curcumin/ turmeric factory, dyes, essential oils, aroma chemicals, cultivation techniques, field’s establishment, and many other projects. More projects were offered to him but he returned to India

62.VIETNAM GOVERNMENT (1985-1992) Institutes of Vietnam ,examples like Institute of Materia Medica (Hanoi) headed by Madam Knu were upgraded with latest technology and scientific infrastructure at both Hanoi and Ho Chi Minh, all funded by UN. (Serial no 42, UNIDO/UNDP 1985-1992). He developed large cultivation farms and factories for medicinal and aromatic plants at Saigon (Ho Chi Minh City), for projects like berberine from Berberis, curcumin from rhizomes of Curcuma longa / haldi and many other projects for Vietnam government. . (See above topic).

63.USA-HOUSTON TEXAS UNIVERSITY (1992) - Dept. of Pharmaceutical Sciences for lecture on biologically active molecules at the University institute.

64.POLISH HERBAL PHARMACEUTICAL COMPANY “HERBAPOL” (post 1992) for identifying joint ventures with India, complimentary task.

65.UN - AFRICA CONSULTANCY-- FOR UN PROJECTS (1993) –See OAU BELOW www.flickr.com/photos/13059662@N06/6506000399/

66.AFRICA-ORGANIZATION OF AFRICAN UNITY (OAU-1993) - to help in development of Africa by formulation of United Nations funded developmental projects in Africa, Mozambique, Swaziland, and Maputo.(see above topic).

67.UNIDO / FAO (FOOD AND AGRICULTURE ORGANIZATION) PROJECT - ON NON WOOD FOREST PRODUCTS - SIX MONTHS PROJECT FOR, UNITED NATIONS (1994) (FAO UN PROJECT TF/GLO/94/009/11-01) –assigned as international expert to prepare UN project lead paper /keynote address on non wood forest products for “International Symposium on Forestry” on occasion of World forestry day at Djakarta, Indonesia. The compilation is published by UN/FAO-Viale dells Terme di Caracalla, 00100 Rome, Italy. (International Expert Consultation on non wood forest products, 1995), article 4.2.1 (Processing, refinement and value addition of non wood forest products –T. De Silva and C.K. Atal)).

A.http://www.fao.org/docrep/v7540e/v7540e00.htm

B.http://www.fao.org/docrep/v7540e/V7540e18.htm

68.SAARC SCIENTIFIC CONFERENCE (COLOMBO, SRI LANKA)–MEMBER OF INTERNATIONAL DELEGATION OF EXPERTS FROM SAARC COUNTRIES HELD AT SRI LANKA , 1995- international experts scientific conference of SAARC countries at SAARC Colombo scientific Conference held in 1995,third week of October.

OTHER SIGNIFICANT INTERNATIONAL CONTRIBUTIONS

69.WORLD AUTHORITY ON CROTALARIA –

A.Solving the outbreak of mysterious Phoolan bimari disease (epidemic of swelling of body in Sarguja district in Madhya Pradesh, India). Several teams investigated this baffling disease, including All India Institute of Medical Sciences, New Delhi. It was being attributed to some new disease of infectious etiology. This was solved by Dr. Atal when the cause was suspected and subsequently found to be toxicity by crotalaria seeds as food adulterant .It was covered in the national news. A team under Dr. Prabhay Singh Jamwal was deputed to the affected area with the instructions to collect all weeds in the fields particularly focusing on suspect Crotalaria. The team returned with several specimens but was unable to find Crotalaria. However on closer scrutiny the rogue plant was identified by Dr. Atal based on examination of unusually tiny but typical seeds of the plant among the sample specimens brought. Further research confirmed the toxicity due to Crotalaria plant.

B.Numerous serial research publications on Crotalaria have been published.

C.On the basis of these numerous publications , WHO appointed Dr. Atal as expert on Crotalaria toxicity and deputed him as consultant to USA, (Oct, 1981) for division of Chemistry and Physics and Division of Toxicology, Bureau of Foods, Food & Drug Administration (FDA) USA / and Pan American Health Organisation (PAHO-USA). Dr. Atal then conducted several lecture tours all over USA (wherever Toxicology work was going on) for toxic plant residues and adulteration in foods and cereals, isolation, detection of hepatotoxins in food chain, especially Crotalaria toxin which had caused morbidity / mortality in USA.

70.INTERNATIONAL IMPACT OF WORK-. Dr. Atal, a student of internationally acclaimed Pharmacognosist Prof. A.E. Schwarting (USA), has been one of the leading International multidisciplinary Pharmacognosists. He was a based internationally as green card US resident and as UN consultant for several projects internationally for about 12-13 years. He served as international multidisciplinary consultant to numerous major international organizations, world bodies, several countries and several United Nations organizations. Multiple multimillion US dollars UN projects successfully implemented/formulated by him have resulted in significant international socioeconomic benefits for the developing world like Vietnam. His drug development projects (Serial no 92-104, drug discovery) include internationally marketed formulations like Sallaki by Gufic (India, Europe, other countries) and Debelysin by Herbapol (Ukraine, Byelorussia, Poland etc). He has several “first reporting’s in the world” and new pioneering concepts in science, like discovery of plant immunomodulators (from rasayanas) and concept of bioenhancers in medical science. It has led to official launching of world’s first bioenhanced TB drug Risorine on world TB day 2011, which was also presented to world dignitary Mr. Bill Gates (Chairman, Microsoft), by Government of India at Delhi. As a world authority on Crotalaria he was invited as consultant to USA (by USFDA, PAHO, WHO) on Crotalaria toxicity. He has also held many international patents. He has also taught internationally in department of biosciences, Nebraska, USA and U. Conn, USA. His international reference books are inevitably found in libraries globally in plant research institutes and extensively quoted internationally in research studies. These are also used in post graduate Pharmacy teaching institutes all over India (refer author writer). His numerous research articles in prominent international journals are also extensively quoted internationally as references. He has been on panel of the prestigious “International Journal of Ethno-Pharmacology”, by Elsevier, Ireland. (Serial no 184-211, author, writer).He has delivered lectures in several countries, chaired international conferences and his UN compilation was presented on world forest conference at Indonesia.

COUNTRIES TRAVELLED FOR INTERNATIONAL INTERACTIONS

71.COUNTRIES TRAVELLED- Conferences, Consultancies, Lectures, Advisory, Collaborations, Travel tourism –(about 30-35 countries travelled, in alphabetical order, passport data) are Austria /Vienna-(1983, 1984, 1986, and more visits), America (USA-1954-57, 1974, 1981, 1992, 2004), Africa, Mozambique , Swaziland, Maputo, Britain (1974,1984, 1979,1992), Bulgaria / Sophia-For Rose Oil,(Sep, 1981), Burma/Rangoon(Myanmar)-(1981), Bangladesh (1984), Belgium (1958) , Canada (1974, 2004), Czechoslovakia (1978, 1981, 1993??), Cambodia / Ankorwat (1992), Egypt /Cairo-Port Said-(1954), France (1980) , Greece (1981), Germany / Munchen, Deutschland-(1978, 1985), Hungary / Budapest (1972), Hong Kong (1986, 1988), Holland (1978, 1984, 1985),Italy, Indonesia / Bali, Djakarta , Jogjakarta(1992), Lebanon , Macau (Portugal Island 1988), Marseilles /Azure Blue Coast, Philippines /Manila – (1991), Poland (1972, 1978, 1981, 1993) Pakistan- (Place Of Birth), Rome, Sri Lanka (1995), Singapore (1987, 1992), Sudan, Switzerland (1993), Tashkent, Thailand - (Multiple Visits) ,USSR / Tashkent (1981), Vietnam (Multiple), West Indies (Trinidad And Tobago-1979),Andaman Nicobar islands(India).

72.INTERNATIONAL LECTURE TOURS, KEYNOTE ADRESSES Examples include lectures in five cities and various institutes of Hungary / Warsaw, Poland on invitation from Polish academy of Organic Chemistry headed by the Director Dr. Kocor, (pronounced kochur),lecture on biologically active molecules in 1992 in Houston University, Department of Pharmaceutical sciences, Houston, Texas, USA on invitation by Dr. Vishnu Das Gupta of same department, lectures in Vietnam (Hanoi and Ho Chi Minh) and in 1991 he accompanied Vice Minister, Ministry of Health, Vietnam Government, on a trip to India on educational, scientific tours. On 7th Feb 1991, he was a resource speaker on fractional distillation of essential oils with Mr. Salvador Fanaga and Mrs. A. Punruckvong at the Second UNIDO workshop on essential oil industry at Manilla, Philippine. He conducted several lectures in USA, Germany, UK, USSR, France, and West Indies (on essential oil distillation technology and solar drying). SEMINARS – he has organized, attended, participated and lectured in national and international seminars. Dr. Atal’s compilation/monograph on non wood forest products under UN consultancy was presented as a key note address on the World Forestry conference at Indonesia (delivered by Silva). He delivered keynote address at RRL, Jammu on event of Workshop on Radioimmunoassay, silver jubilee celebrations of RRL, Jammu, Dec, 1-6, 1982, inaugurated by Prof. J. S. Bajaj, HOD (Medicine), AIIMS, Delhi, and delivered keynote address on the first National symposium on Survey and Cultivation of edible mushrooms in India, the welcome keynote address was delivered by him. Jamia Hamdard, 2003 - Delivered keynote address at ‘Pharmacy week’ in Nov 2003 at Jamia Hamdard (newsletter , Jamia Hamdard “spreadsheet” march 2004 issue) –Theme of the week was “Pharmacists for the promotion of future free of Tobacco(page 2 Para 2- flashback). www.jamiahamdard.edu/PDF/News Letter_JH.pdf He has delivered multiple lectures on History of India, particularly Punjab history.

 

INDIA-SOCIOECONOMIC DEVELOPMENT

 

INDIA- Tea, Hops, Rural Development Projects, Xanthotoxins, Essential Oil Industry, Mint, Agro Industries, Pharmaceutical industry, Calcium gluconaterutin, Solid herbal extracts, vanillin, liquor lignin, straw/mill board, trisodium orthophosphate, turpentine, cellulose derivatives, solar dryers, borax plant, fruit vegetable processing, chhang technology, Fisheries, aquaculture , Sericulture, Leather , Fur ,wool, suedes, chamois, Tanning, Chinchilla / rabbit farming , rabbit wool, fast growing tree species , mass forestation , large scale plantation of fast growing tree species, Willow, Cash crops, paper pulp/board technology, pine needle , pine wool, pine boards, Mushroom farming, ethnopharmacology studies, food technology, J&K Mountain Cheese (maash kalari), termite control , eradicating superstition.

In India, he has established new industries or helped transform the import dependency in some existing industries into mass production and export, leading to generation of wealth for the country, including rural society and rural based industry. This has been achieved through science and technology research and development, agro industries, drug discovery/drug development, essential oil industry, award winning work in economic transformation of rural masses, rural and industrial technology development, utilization of waste into viable useful industry with added ecological benefit, resultant benefit to the industries based on plant and rural sciences, discoveries, processes development, all plant sciences, breeding and propagation technology ,turnkey jobs etc. Rural development projects resulted in socioeconomic transformation of the rural masses which won recognition like the FICCI award presented by the honorable President of India, UN grants and several other awards. Several plant based drugs like Xanthotoxin and many others helped India become self sufficient in technology and saved the precious foreign exchange reserves, particularly in the financially stressful seventies and eighties and beyond till date. Research in Essential oils from plants particularly Mint, Ocimum, Cymbopogan, etc used in health formulations, food industry, and essential oil industry helped change the socioeconomic status of the industry as well as rural masses. Developing technology for bold crystals of mint for the first time in India and introducing high mint yielding plants resulted in a sort of green revolution in mint which is now a massive thriving industry today. Introducing and establishing expensive Hops successful in India for the first time changed the socioeconomic status of the rural people of the hills. Implementations of recommendations of Sadasivan committee, of which Dr. Atal was a core member, helped the struggling tea industry from international competition. Projects on submerged fermentation initiated in June 1975, won the Andhra Pradesh prize (Serial no 7, award section) at the import substitution competition for developing process for production of Gibberellic acid.

 

161.TECHNOLOGIST, SADASIVAN COMMITTEE FOR REVIVING THE INDIAN TEA INDUSTRY- appointed as a prominent member and Technologist of Sadasivan committee (1976), Ministry of Commerce, Government of India to prepare report and give recommendations for improving tea production cost effectively in the face of rising global competition (especially from countries like Kenya, Sri Lanka & Indonesia).Implemented recommendations had a very good boosting effect on the sagging tea industry, thereby rescuing the tea industry from international competition.(See Current science, Vol 81, No. 7, October 2001, page 845, last paragraph- T. S. Sadasivan - A tribute, www.iisc.ernet.in/currsci/oct102001/845.pdf www.flickr.com/photos/13059662@N06/6506102687/in/photostr... www.flickr.com/photos/13059662@N06/6970444265/in/photostream

162.ESTABLISHING NUMEROUS INDUSTRIES IN INDIA-Numerous pilot plant scale and commercial factory scale industries were established all over India based on the numerous technologies developed by RRL Jammu. (Serial no 152-159, processes developed).

163.CONSULTANCIES BY RRL ALL OVER INDIA -Examples include Calcium gluconate by fermentation (through NRDC-at Srinagar), plantation of rutin bearing Eucalyptus spp. at Kangra, Himachal Pradesh, manufacture of solid herbal extracts units (Delhi based Alok pharmaceuticals), vanillin from sawdust(Bombay), straw/mill board unit(Taran Taran, Punjab), cultivation of Clocimum and Jamrosa, downstream end products eugenol, geraniol (Jammu), cellulose derivatives esp. microcrystalline cellulose carboxymethyl cellulose (Amritsar and also Bombay), bolder crystals of menthol (Delhi), trisodium orthophosphate (Jammu), turpentine fractionating unit, liquor lignin waste from paper pulp industry (Madras), modification of resin refining kettle (Jammu).

164.INTRODUCTION OF TURN KEY SYSTEM FIRST TIME AT RRL, JAMMU -for processes developed, RRL adopted the turn key system, a useful tool to the end user (industry). www.flickr.com/photos/13059662@N06/6952344393/in/photostr... Examples are technology of Diosgenin, (Govt. of Tamil Nadu, West Bengal, and Burmese Government provided through govt. based organization NRDC), Menthol (Burma through NRDC), Hops (J&K and Himachal Pradesh), Pine needle board (Himachal Govt), etc. The turn-key process includes providing all the steps involved to establish a location including the site selection, space utilization, technology, construction, coordination and complete working installation

165.DEVELOPMENT OF FAR FLUNG REMOTE AREAS OF JAMMU KASHMIR, INDIA- difficult or inaccessible areas like Kargil and Ladakh were provided rural training, solar dryers, borax plant, fruit vegetable processing, chhang technology (Ladakh beer),etc. www.flickr.com/photos/13059662@N06/6970221243/in/photostr...

166.JAMMU , KASHMIR AND LADAKH, INDIA (FICCI AWARD,UN GRANTS AWARD)- Numerous projects like Fisheries, aquaculture , Sericulture, Leather , Fur ,wool, suedes, chamois, Tanning, Chinchilla / rabbit farming , rabbit wool, fast growing tree species , mass forestation , large scale plantation of fast growing tree species, Willow, Cash crops, paper pulp/board technology, pine needle & pine wool, Indian mint and Hops industry(a major socioeconomic breakthrough in brewery industry), Mushroom farming, solar drying technology especially in Ladakh and far flung areas of Kargil, extraction of Borax in Ladakh (PUGA valley) using geothermal energy, agro technology, ethnopharmacology studies, food technology, J&K Mountain Cheese (maash kalari), termite control , eradicating superstition - oham shikni in some areas of J&K), use of environment friendly alternate energy, forestation drives, environment pollution control (apple pomice was a pollutant , discarded / dumped in the river Jhelum in J&K as a waste which contributed to the environmental pollution. RRL in collaboration with the Army Horse and mule division designed and set up 20 foot tall silos for fermenting the Pomace to produce nitrogen rich feed for the mules and thereby preventing river pollution).For award of UN grants for rural work in J&K, Serial no 8, award section. www.flickr.com/photos/13059662@N06/6972288641/in/photostream www.flickr.com/photos/13059662@N06/6824267612/in/photostr...

167.ESTABLISHING AND DEVELOPING FIRST HOPS INDUSTRY SUCCESSFULLY IN INDIA (JAMMU, KASHMIR & HIMACHAL)-India developed the Hops technology and established Hops industry successfully for the first time in India. As a result there was a significant saving in foreign reserve (import substitution) which was earlier consumed in import of expensive Hops. See Prof. P. N. Mehra award. www.flickr.com/photos/13059662@N06/5782130675/sizes/l/in/... www.flickr.com/photos/13059662@N06/6506235095/in/photostream books.google.com/books?id=Y3Y_AAAAYAAJ&source=gbs_sim...

168.HIMACHAL PRADESH, INDIA- pine needles Fiber board factories (a first in the world), with turpentine as a parallel by product, establishing CSIR complex at Palampur (now called IHBT) in 1983, appointed as first head this institute , establishing first Hops industry in India, including Lahul area of Himachal Pradesh. Tea industry in Himachal and India was also greatly helped by the efforts of Dr. Atal (See Sadasivan committee).Rutin industry in Himachal Pradesh is mentioned in next point below.

169.BIOFLAVONOID “RUTIN INDUSTRY”- As more and more high yielding species of Eucalyptus as a source for Rutin were discovered in the world, the best raw material source came from dried E. macrorhynea leaves (10-12% w/w yield) primarily used in Australia. The Imported seeds of Eucalyptus macrorhynea were found to perform best in salubrious climate of Palampur in the state of Himachal Pradesh and the leaves were found to give higher yield of Rutin as compared to Australian raw material sources. This was a big commercial breakthrough as Indian species were very low in Rutin content and the high yielding imported variety performed equivalent or better in Indian climate .A factory for production of Rutin was set up at Dhanaulti / areas near Pathankot to supply Rutin to Pharmaceutical industry. Palampur branch of RRL played a leading role in popularizing cultivation of Eucalyptus macrorhynea for the very first time in India. (Serial no 105-112,first reporting in India). Dr. Atal also propagated the coppicing method (including Eucalyptus species) to increase the yield of plant raw material leaves tremendously contributing to further increasing the quantity of finished product.

170.SIKKIM , INDIA 1984-85, Dr. Atal was invited by the Sikkim State as a consultant to identify the raw materials, viable projects from the forest and the state with industrial potential. Several ideas and projects were identified and a project report was handed over to the Sikkim Government / Hon. Hon. Governor Shri Talae Yar Khan for implementation.

171.PIONEERING WORK IN ESSENTIAL OIL AND AROMA CHEMICAL INDUSTRY IN INDIA AND INTERNATIONALLY (AS UN CONSULTANT) - (Serial no 115,essential oils).

172.CONTRIBUTIONS IN SUCCESSFUL MINT INDUSTRY IN INDIA-( Serial no 115, Essential oils). Dr. Atal developed and promoted technology for manufacture of bold crystals of mint / mark into boards, a big boost to the mint industry in India. Japanese mint industry became “Rs 100 million” industry by the beginning of 1980’s, and the Tarai area of UP state alone was a 10 crore per annum industry in the mid eighties. India became self sufficient in mint in mid 1980’s. Today China and India are world leaders in mint after further boosting efforts put in by CIMAP in the nineteen nineties. Japanese mint has become the single largest essential oil crop of the country. He also was appointed as international consultant in mint technology in 1981(Burma).

173.DEVELOPMENT OF MINT INDUSTRY IN BURMA 1981–invited as CSIR consultant to the Burmese Government on the mint technology, Menthol distillation plant, transfer of technology for production of bold crystals of Menthol from Mentha arvensis, setting up a pilot plant / demonstration unit (Menthol extraction plant) and imparting training techniques to Burmese scientists.

174.DIOSGENIN INDUSTRY IN INDIA - Dioscorea deltoidea and solasodine as new source of production of Diosgenin, a steroidal compound which is the feed raw material for synthetic production a variety of many steroidal hormones. Diosgenin ex D. deltoida & D. mexicana for supply of diosgenin as a raw material to Pharmaceutical industry for manufacture of steroidal therapeutic agents –several factories were set up for commercial production of diosgenin with technical knowhow ,establishing turnkey projects with chemical engineering know how, particularly 16-DP technologies were transferred to government of West Bengal and Tamil Nadu.

175.DIOSGENIN TECHNOLOGY / INDUSTRY IN BURMA 1981- Pharmaceutical research Department of Central Research Organization, Burma was provided Diosgenin –Progesterone plant and technology at Hmaw-Bi, Rangoon. www.flickr.com/photos/13059662@N06/6970421821/in/photostr...

176.UN CONSULTANT TO BANGLADESH GOVERNMENT, 1984 - for helping Bangladesh CSIR, for technology demonstration, for upgrading/modernising their Pharmaceutical formulations, examples like chavanprash. repository.searo.who.int/handle/123456789/14829

177.PHARMACEUTICAL INDUSTRY)- DRUGS IN THE NATIONAL AND INTERNATIONAL MARKET– Sallaki (Gufic pharmaceutical company -India and international marketing), two Antitubercular formulations Risorine / Risorine kit (Cadila Pharma), Debelysin(Herbapol of Poland, international marketing),Livzone(Hind Chemicals),and others. (see details in drug discovery).

178.CONSULTANT TO UN HEAD OFFICE AT VIENNA, AUSTRIA- 1984 –for formulating projects for Vietnam.

179.CONSULTANT FOR UNDP, UNIDO AND VIETNAM GOVERNMENT –for implementing multiple multimillion US dollars projects in Vietnam.

180.UNITED NATIONS – RRL, JAMMU TECHNOLOGY TRANSFER-pilot plants based on technologies developed at RRL, Jammu under Dr. Atal for distillation and fractionation of Aroma chemicals and natural dyes were later fabricated, Installed and commissioned on turnkey basis under UNIDO projects implemented at Vietnam under Dr. Atal.

181.UN CONSULTANCY FOR PROJECTS IN AFRICA -1993 – for projects recommendations in African countries.

182.ANDAMAN NICOBAR ISLANDS, INDIA –Prepared a report on viability of large scale herbal farms (medicinal and aromatic) in Andaman Nicobar islands, Port Blair (1993), as a part of consultancy for Khaitan Industries.

183.INTERNATIONAL EXCHANGE PROGRAMMES -many scientific exchange programmes were organized between Vietnam, United Nations, India and many other countries. Similarly these were also carried out in his capacity as director of RRL Jammu, like the Soviet delegation of Pharmaceutical experts under Mr. A. I. Vinogradov visited RRL in March 1982 and appreciated the work done at RRL.

184.SOME SIGNIFICANT TECHNOLOGIES DISCUSSED ELSEWHERE

A.Xanthotoxins from two plant sources – till early 1970s it was being imported into India. After technology was developed by Dr. Atal, it led to a significant savings in import and is being exported to European and other countries. See first reporting in India.

B.Submerged Culture, Gluconates, Giberellins Etc – Significant savings in import, See Award section.

C.Conversions of waste into viable utilizable Industry- Serial no 142-146, environment conservation, See first reporting in the world, See FICCI Award.

 

Acetaminophen (the active ingredient in Tylenol®) is toxic to cats... and to humans.

 

The United States Food and Drug Administration (USFDA), which oversees the safety of food and medicines, has received numerous valid complaints about liver damage and death from consumers who have taken acetaminophen AS DIRECTED. Resultantly, because of the well-known liver toxicity problems associated with acetaminophen, the FDA is rapidly moving toward removal of acetaminophen from an OTC (Over The Counter, i.e., available without prescription), status medication. (Read the FDA's warning to Healthcare Professionals about acetaminophen dosing.)

 

While the antidote for acetaminophen overdose is acetylcysteine (Mucomist®), often, dosing with the antidote is somewhat like trying to herd cats insofar as the damage is often done once the medication is administered.

 

Naturally, the maker of Tylenol® - McNeil Consumer Healthcare, a division of Johnson & Johnson - has lost many court cases for wrongful death claims when infants & children died after being administered toxic level doses of the medication, which were GIVEN ACCORDING TO PACKAGE INSTRUCTIONS.

 

As well as those well-known problems, acetaminophen is NOT RECOMMENDED for people who consume beverage alcohol, because the combination of the two accelerates and intensifies liver damage.

 

Of course, as I mentioned at the outset, acetaminophen is toxic to cats.

Presented to Prof. Dr. C. K. Atal for discovery and validation of world's first bioenhancer Piperine, thereby leading to scientific validation of bioenhancers concept and consequently resulting in development of world's first bioenhanced antitubercular formulation Risorine officially released on world TB day may 2011 by Govt. of India and which was also presented to Philanthropist Mr Bill gates by the Indian Government.

 

CONTRIBUTIONS IN MEDICINE

REFERENCES-

www.jaim.in/text.asp?2010/1/2/96/65073 www.linknaturalproducts.com/downloads/lnp-digest-v6-2010-.... webcache.googleusercontent.com/search?q=cache:L5kfQKgjkMw... www.herbalnet.org/events.htm www.dailyexcelsior.com/dr-atal-conferred-edpa-award-appre...

www.flickr.com/photos/13059662@N06/13401939445/

  

HEALTH, MEDICINE, DRUGS, TOXICOLOGY

PHARMACOGNOSY, DRUG RESEARCH, DRUG DISCOVERY, DRUG DEVELOPMENT, NEW CONCEPTS, NEW MECHANISMS OF ACTION OF DRUGS, MEDICINAL PLANTS, AYURVEDA ETC

 

“It takes more than 10-15 years and approximately 500-600 million dollars to put a new drug into the market. Dr. Atal has provided a basket of drugs, molecules, medical concepts and novel mechanisms of action of drugs for the benefit of patients, researchers and medical community.

1.MEDICAL FRATERNITY AWARDS & HONOURS- drug research and development, medicinal plants research,–details in award section.

A.IMA AWARD- Indian Medical Association Award (IMA- EDB) Chikitsa Seva rattan (ratna) award for bioenhancers.

B.EDPA AWARD of appreciation, 2014.

C.Guest of honor at seminar on Bioenhancers jointly organized by Indian Medical Association (EDB) and East Delhi Physicians association at Delhi.

D.Inaugurated the annual conference, Hematology and blood transfusion at Govt. Medical College, Jammu.

2.OTHER AWARDS(drug development , medicinal plants)

A.Dr. I. C. Chopra Science and Technology award to Dr. Atal for several pioneering drug discoveries and drug development.

B.Professor P. N. Mehra Memorial botany award for plant sciences including work on medicinal plants.

3.AWARD WINNING RURAL HEALTH, NUTRITION, RURAL RESEARCH AND DEVELOPMENT DONE AT RRL

A.FICCI AWARD presented to RRL for rural development projects including work on rural health

B.UN GRANT for rural aquaculture development given to RRL (rural nutrition).

4.MEDICINAL CONSULTANCIES

A.World Health Organization projects in Bangladesh and USA (see toxicology).

B.UNDP projects on medicinal plants in Vietnam.

5.LITERATURE (Serial no 184-211,details in author section) -

A.World reference book on medicinal plants used globally in research institutes/universities

B.Numerous research papers in reputed national & international journals.

6.TOXICOLOGY- INTERNATIONAL AUTHORITY on Crotalaria and its Toxicity in Human Food Chain (Crotalaria Adulteration and Toxicity) and WHO / USA Consultancy

A.Solving the mysterious disease in Sarguja district, Madhya Pradesh, India as crotalaria toxicity.

B.Appointed as consultant by WHO to USA (WHO, PAHO and USFDA) as world authority on Crotalaria and toxicity in human food chain.

C.Published several serial research articles on Crotalaria.

7.PUBLIC & RURAL HEALTH- projects include successful control of external parasites (ectoparasites) like louse control using bio-antiparasitic agents , example-(1975-76) by use of Acorus calamus oil and mustard oil, Guinea worm infection (1976-77) by anti zooplankton measures like introduction of pond fishes in villages which thrive on zooplanktons. Aquaculture (rural supplementation of income and nutrition won the UN grant).

8.WORLD’S FIRST GEOTHERMAL ENERGY BORAX EXTRACTION PLANT (Puga-Ladakh-1976)- world’s highest-factory of its time, first in India and perhaps first and only example in the world to extract borax by innovative use of geothermal energy having medicinal use.

9.INDIA’S FIRST IN DRUGS AND MEDICINE

A.Breakthrough technology in mint - technology for manufacture of bolder crystals of menthol//marc into boards which is used in medical formulations.

B.Xanthotoxin manufacture from two plant sources-(ammi majus & heracleum candicans).

C.Risorine-only Indian drug from India released on world TB day, and presented by Indian government to world dignitary Mr. Bill Gates.

D.Sallaki- the second Indian “single plant based scientifically researched modern drug based on traditional Indian system”.

E.First to introduce / popularize superior imported eucalyptus macrorhynea seeds, a source of Rutin used in medicine.

F.Founder/signatory-CCRAS system of medicine.

10.DISCOVERY OF NEW MECHANISMS OF ACTION IN DRUGS

A.Bioenhancers- they increase blood levels of drug (bioavailability) and drug efficacy (bioefficacy) by inhibiting first pass metabolism and increased absorption of drug. Several more mechanisms have been studied / postulated for this effect.

B.Plant Immunomodulators from Rasayanas - first reporting in science.

11.DISCOVERY OF NOVEL OR BETTER MECHANISMS OF ACTION OF DRUGS- (Drug discovery, mechanisms of action of those drugs and first reporting in science in drugs are overlapping topics) see details in next topic and (Serial no 105-112,first reporting in science)

A.Potassium Embelate (centrally acting non narcotic orally effective analgesic acting on new undiscovered receptors in the brain).

B.Sallaki-Non steroidal anti inflammatory gastro protective plant analgesic (active ingredient Boswellic acid) working through inflammatory pathways (all other existing NSAID drugs are ulcerogenic).

C.Vasicine- bronchodilatory, oxytocic and platelet dysfunction/platelet number corrector actions.

D.Anti urolithiatic drug Debelysin (internationally marketed)-See details below.

E.RLX- Anti inflammatory cum bronchodilator drug. All other asthma drugs are either bronchodilators or else anti-inflammatory drugs.

12.WORLD’S FIRST IN BIOENHANCERS

A.Discovery of world’s first bioenhancer Piperine which is also the world’s first plant based bioenhancer. Research includes first deriving the mechanism of action.

B.First coining of the term Bioavailability enhancers (Bioenhancers).

C.This discovery was proven on world’s first experimentally bioenhanced drugs Sparteine and Vasicine.

D.Published the first scientific evidence based reference on Bioenahncers (IDMA bulletin).

E.This discovery scientifically established a new chapter in medical science.

F.Starting the first bioehnanced antitubercular project which led to development of world’s first bioenhanced antitubercular drug Risorine developed by IIIM Jammu, released by Govt. of India on world TB day 2011 and presented to Mr. Bill Gates of Microsoft.

DETAILED DESCRIPTION

DISCOVERY OF NEW CONCEPTS /FIRST REPORTINGS IN MEDICAL SCIENCE

13.DISCOVERY OF WORLD’S FIRST BIOENHANCER PIPERINE (COMMERCIALISED):

A.PIPERINE is the world’s first proven bioenhancer which was discovered and established by Dr. Atal. Spartine and Vasicine were the first experimental bioenhanced drugs, which established the world’s first bioenhancer concept (See next topic) and which ultimately led to development of world’s first bioenhanced antitubercular formulation Risorine.

B.SIGNIFICANCE OF DISCOVERY OF PIPERINE - It was the first time that a molecule was discovered which could increase the potency of several classes of existing drugs even after being administered at reduced dosed. This made the formulation more effective (bioefficacy) while dose reduction meant reduced cost of drug and reduced side effects of the drug. Prior to this the existing methods were confined to Physical methods only, like micronisation, timed release, site release formulations etc.

C.HISTORY-Bioenhancers were first scientifically documented in 1979 at RRL, Jammu. The reason for arriving at the Bioenhancer hypothesis by Dr. Atal was based on a clue on Trikatu obtained after scrutiny of Ayurvedic handbook compiled by another research institute of CSIR. He observed that a large number (about 75%) of herbal formulations used for a large variety of diseases incorporated Trikatu, or one of the ingredients of Trikatu, namely Piper longum. He posed two questions. What was piper doing in so many formulations? Is it effective against all the illnesses? Since piper cannot be a panacea, so other reasons were thought of and one likely postulation was that it probably increased the potency/ bioavailability of formulations. Further research established the bioenhancer concept. Radiolabelled Vasicine and Spartine which were already being used in other experiments at RRL, were used for bioenhancing experiments, and became the first experimental drugs in the world to be scientifically bioenhanced by Piperine in 1979 at RRL, which established the concept. Subsequently several other classes of drugs were also bioenhanced successfully, research papers were published by RRL , Piperine was patented internationally, research scholars were granted doctorate degrees on bioenhancer research and drug development project on anti tubercular formulation was initiated at RRL. With further research by others, bioavailability enhancers were renamed bioenhancers in short, because research has indicated that Piperine may increase efficacy of drugs due to mechanisms other than increased bioavailability (bioefficacy enhancer + bioavailability enhancer = bioenhancers). About 50 years earlier, Bose in his Pharmacopoea Indica while describing the antiasthmatic activity of Vasaka leaves had made an observation that addition of long pepper to Vasaka increased its efficacy. However, no explanation for this observation was put forth by anyone in science, and it remained an observation overlooked and uninvestigated for about 50 years till the discovery of bioenhancers at RRL, Jammu in 1979 based on a clue from Ayurveda.

14.ESTABLISHING NEW CHAPTER OF BIOENHANCERS IN MEDICINE-

A.NEW CHAPTER IN SCIENCE- With the discovery of Bioenhancer Piperine a new chapter in Medicine was established. The term “Bioavailability enhancers” (later renamed bioenhancers or drug boosters) was first /coined at RRL Jammu. The breakthrough was first published by Dr. Atal in 1979 in IDMA bulletin (Atal. C.K., I.D.M.A. Bull, 1979, 10, 36- “A breakthrough in Drug Bioavailability” – A clue from age old wisdom of Ayurveda”. This term did not exist anywhere in medical treatment, drug industry; textbook or scientific literature till bioavailability enhancer Piperine was discovered and authenticated.

B.SIGNIFICANCE OF DISCOVERY BIOENHANCER CONCEPT -This revolutionary award winning globally recognized breakthrough is a basic discovery which has opened new concept/chapters of Bioenhancers in science in the field of drug bioavailability. As a result, it has opened endless new molecules, drugs, classes of drugs waiting to be bioenhanced and newer bioenhancers waiting to be discovered. Several bioenhancers have been discovered after this discovery, but Piperine still remains the most potent bioenhancer till date. This is also an example of traditional drug influencing multiple classes of modern drugs, nutrients and Xenobiotics. Details are provided at the last page.

C.BENEFITS OF BIOENHANCERS- Bioenhancers act like a catalyst and make the formulations more potent even at lesser dose. Reduced dose also makes the formulation safer, cheaper, and better tolerated by patient, with lesser chance of drug resistance (due to better acceptance, better compliance and increased bioefficacy). Moreover added ecological benefits are due to reduced requirement of raw material needed for plant based drugs, particularly for “less bioavailable” plant based drugs or for rare and scarce plants, example being anti cancer drug Taxol. www.jaim.in/text.asp?2010/1/2/96/65073(J-AIM-journal). docs.google.com/viewer?a=v&q=cache:BULgW-7SSm8J:www.n... ( CSIR newsletter).

15.DRUG DEVELOPMENT PROJECT ON WORLD’ FIRST BIOENHANCED ANTITUBERCULAR DRUG - (Risorine/Kit based on Piperine officially released on World TB day, 2011)- Work was started by Dr. Atal on developing Piperine based antitubercular formulation (reference given below) keeping in mind the dire need of the society . Thereafter the world’s first Piperine bioenhanced anti tubercular formulation Risorine/Risorine kit was developed by CSIR (public private partnership) as a novel safer cheaper TB drug with fewer side effects. It was released on world Tuberculosis day 24th March 2011 in presence of current and former ministers for science and technology, India, Director General CSIR and others at Delhi, India and also presented to Mr. Bill Gates. It is almost 50 long years after which something new has happened in the field of tuberculosis research and treatment. Piperine was extensively investigated, researched and took unusually long time to get the concerned permission for launching it in market as Risorine (company launching in 2009 by Cadila Pharmaceuticals and official CSIR launching on world tuberculosis day 2011).In the meantime keletra (Lopinavir/ritonavir) was discovered and officially launched as bioenhanced antiretroviral drug(US FDA approval in 2000). Thus Risorine became the second officially marketed bioenhanced drug in world after keletra even though Rifampicin was experimentally bioenhanced much earlier. However Risorine is still the world’s first bioenhanced marketed antitubercular drug. For details of the World TB day events, See two links below. Reference- Influence of piperine on rifampicin blood levels in patients of pulmonary tuberculosis, J Assoc Physicians India. 1985 Mar; 33 (3) : 223-4 www.ncbi.nlm.nih.gov/pubmed/4044481http://pib.nic.in/news... csirindia.wordpress.com/2011/03/26/world-tuberculosis-day... RECOGNITION OF PIPERINE DISCOVERY - Bioenhancer discovery has led to the successful development of world’s first bioenhanced antitubercular drug Risorine in market.

A.Globally recognized and accepted discovery by scientific community, Wide media coverage, DD news coverage of Risorine release, internet reports.

B.Dr. I. C. Chopra award, 2000 given to Dr. Atal for plant based drug discoveries including Piperine.

C.Indian Medical Association’s Chikitsa Seva Rattan (ratna) award, IMA-EDB given to Dr. Atal for bioenhancers.

D.EDPA award of appreciation, 2014 given to Dr. Atal for bioenhancer research.

E.Many Medical Conferences on bioenhancers have been held like the one jointly conducted by Indian Medical association (EDB) and East Delhi Physician association at IMA hall (EDB) on 8th May, 2010.

F.CSIR/Govt. of India’s official launching of bioenhanced Risorine on world TB day, 2011 at Anusandhan Bhawan, Delhi.

G.Presentation of Risorine to visiting dignitary Mr. Bill Gates on world TB day, 2011.

H.IDMA research award 1981-82, discipline Pharmacology, at hotel Centaur, Mumbai (erstwhile Bombay) presented to Dr. Usha Zutshi / J. L. Kaul-on best original research paper on “The impact of Ayurvedic herbals on drug bioavailability” in Indian drugs 1982 Sep vol. 19, pg 476-79.

I.CSIR National Technology award 1993 presented to Dr. Usha Zutshi and Dr. K. L. Bedi, for work on piperine.

J.RRL Jammu alone published more than 25 research papers on Piperine based on 10 PhDs dissertations and doctorate degrees awarded on bioenhancers.

K.Worldwide recognition, research and publication of Piperine and bioenhancers.

16.DISCOVERY OF PLANT BASED IMMUNOMODULATORS (discovered from Rasayanas in Ayurveda and available as formulations in market)-First reported case of plant based immunomodulators from plant sources, discovered from Ayurvedic list of Rasayanas class of drugs, a new concept and a major contribution to science. (Serial no 17,award section-Dr. I. C. Chopra award ).Out of 16 plant drugs, 6 were studied in more detail and thus classified on the type of immune modulation produced, as immunosupressants, immunostimulants and immunocorrecting agents (immunoequiliberating). Example includes Picrorhiza kurroa that went into clinical trials has become a part of numerous modern herbal formulations. Some References - Immunomodulating agents of plant origin. I: Preliminary screening, J Ethnopharmacol. 1986 Nov; 18(2): 133 - 41. C. K. Atal, M. L. Sharma, A. Kaul, A. Khajuria, (See links below and events, CSIR, IIIM , first Dr. I. C. Chopra award)

A.http://www.ncbi.nlm.nih.gov/pubmed/3560991

B.http://www.herbalnet.org/events.htm

17.DEBELYSIN (COMMERCIALISED, INTERNATIONALLY MARKETED) patented renal antilithiatic (lithio-lytic or renal calculi dissolving drugs), based on Dolichos biflora Seeds. Not much is available in allopathic system for renal calculi, although methods exist like surgery, cystoscopic removal, lithotripsy, some uncommon methods to dissolve renal calculi, besides some herbal formulations available in market. Debelysin is a patented, safe, scientifically established drug for renal calculi with an international marketed in Poland, Byelorussia and Ukraine. Reference article -Clinical evaluation of a new antilithiatic drug," Debelysin". T Krzeski, A Borowka, W Gustowski, C.K. Atal, A. Pol J Pharmacol Pharm, 1983 - 35(1):1-6. www.ncbi.nlm.nih.gov/pubmed/6889184

18.ANTIARTHRITIC DRUG SALLAKI – BOSWELLIC ACID AS ACTIVE INGREDIENT- (COMMERCIALISED, INTERNATIONALLY MARKETED)- SECOND HERBAL DRUG IN INDIA- Apart from Rauwolfia discovered by Col. Sir R. N. Chopra in late forties, Sallaki, launched in March 1982, became the second other important scientifically proven major herbal drug based on Indian system of medicine (Ayurvedic and Unani) to formally enter Indian market in five decades post independence ( RRL newsletter April 1982). Belladonna was one more such launch elsewhere but it was not a drug in the true sense because it was launched as tincture for its non specific effects/activity on salivation and pain or else as belladonna plaster for boils which are not “activity” specific. Later Atropine extracted from Belladonna became a pure modern drug. After Rauwolfia, Sallaki was “second” in India for the following reasons. It was the second formally launched “single plant” based drug like Rauwolfia, its alcoholic extract was validated for activity in animals, activity was also established to be equivalent to crude drug, and lastly, its scientific validation in animals was reproducible (reference-Dr.K.L.Bedi). The Dr. I. C. Chopra award, 2000 was given to Dr. C. K. Atal for plant based drug discoveries particularly Sallaki, (See award section and internet link). Sallaki is also successfully marketed internationally, particularly Europe, as a safe, effective antiarthritic drug and the only non steroidal anti-inflammatory drug devoid of gastrointestinal side effects (ulceration) and instead it has gastroprotective action. www.phytomedicinejournal.com/article/S0944-7113%2808%2900... The effects on lipids were also investigated for the first time which was also done by CDRI, Lucknow, which progressed further into anti lipidaemic drug development. Mechanism of cholesterol lowering effect of Salai guggal ex. boswellia serrata roxb - U Zutshi, PG Rao, S Kaur, GB Singh, S Surjeet, CK Atal Indian Journal of Pharmacology – 1986, vol. 18,issue 3,pg 182-183.Sallaki is also reportedly being manufactured by Gufic Company in Uzbekistan and has a reported market in Russia and Europe, especially Germany. Boswellic acid is marketed by other companies like Himalaya (as Shallaki) and Amway. www.ijp-online.com/article.asp?issn=0253-7613;year=1986;v...

19.VASICINE, VASICINONE, AND ITS ANALOGUES (MARKETED AS AYURVEDIC FORMULATIONS) -OFFER OF US DOLLARS 80,000/- FOR INDO-US COLLABORATION ON THIS DRUG-exhibiting bronchodilatory, oxytocic and platelet dysfunction/platelet number corrector actions. Vasicine from Adhatoda vasica was discovered to control capillary bleeding through action on Bone Marrow. Dr. Atal while on a visit to USA in 1981 was offered Indo US collaborative research on vasicine. A provisional agreement was signed in USA with Farmacon dated 29th Oct, 1981, and agreed that the data be provided to Farmacon research Corporation, 39, South Lasalle street , Chicago Illinois, USA for a sum of US dollars eighty thousand(US $ 80,000/-) plus additional negotiable royalty , subject to CSIR Head office approval and retaining justified rights by CSIR. This was meant to be researched further in USA for possible marketing in USA (& Pakistan) as per agreement with Alan J, Schroeder, Vice President of the company. Since approval was delayed so the advance cheque was returned back to the company in USAL. This was the highest ever recorded amount of that time offered to any of the CSIR laboratories from international companies and original signed documents of agreement are still preserved. www.flickr.com/photos/13059662@N06/6506562555/in/photostream

20.RLX-a significant work on bronchodilatory effects of Deoxy vasicinone (RLX). This molecule is a wonderful anti inflammatory bronchodilator with minimal side effects as compared to conventional existing drugs and having a novel mechanism of action entirely different from others. The existing anti asthmatic drugs possesses either anti-inflammatory or else bronchodilatory effect, whereas RLX has both the properties.

21.POTASSIUM EMBELLATE-THE ONLY DRUG OF ITS KIND- a centrally acting, non narcotic orally effective analgesic, the only molecule of its kind known to exist. This is new molecule acting on so far unknown and undiscovered receptors in the brain (as peripherally it is devoid of anti-inflammatory action and centrally its effect is not reversed by opioid antagonists suggesting some different site of action/receptors in brain). Reference-

A.http://www.ncbi.nlm.nih.gov/pubmed/2561116

B.http://www.ncbi.nlm.nih.gov/pubmed/6541278

22.HEPATOPROTECTIVE FORMULATIONS (COMMERCIALISED): - significant work on plant based hepatoprotective formulations based on many plants. It was launched in the market as Livzone, a hepatoprotective formulation (Hind Chemicals, Kanpur). www.herbalnet.org/events.htm (CSIR- IIIM , Serial no 17 ,first Dr. I. C. Chopra award)

23.TECHNOLOGY TRANSFER FOR ABOVE DRUGS- Sallaki (Gufic Company, Bombay, renamed Mumbai), Hepatoprotective Livzone (Hind Chemicals, Kanpur under Dr. Rohtagi), Piperine Bioenhanced Anti tubercular formulation Risorine/risorine kit (Cadila Pharmaceuticals, Ahemedabad). Immunomodulator Picrorrhiza is being used in many herbal formulations and so is Vasicine. Antiurolithiatic drug Debelysin has been internationally developed by Herbapol from Poland.

A.DRUGS RESEARCHED IN INDIA- Sallaki, Risorine, Hepatoprotectives (Livzone), RLX, Vasicine, Potassium Embellate

B.DRUGS RESEARCHED INTERNATIONALLY- Debelysin

C.DRUGS COMMERCIALISED IN INDIA- Livzone, Risorine, Sallaki

D.INDIAN DRUG COMMERCIALISED INTERNATIONALLY- Sallaki

E.DRUGS DEVELOPED & COMMERCIALISED INTERNATIONALLY-Debelysin

24.PROCESS DEVELOPED FOR INDIA FOR SEVERAL KNOWN AND EXISTING DRUGS – Phytochemicals (Seventeen) ,Drug Intermediates (Three) ,Fermentation Technology (Four) (for detailed list Serial no 152-159,processes developed for India.Broad categories are Processes for medicinal Essential Oils Isolates(like mint), Phytochemicals, Drugs, Intermediates, Pharmaceuticals, Mineral Products(plaster of Paris), Fermentation Technology Products(citric acid),mint etc used by the Medical profession.

25.CONTRIBUTIONS IN AYURVEDA- All drugs mentioned above in drug discoveries are based on medicinal plants and Ayurvedic/herbal plants (Serial no 201-204, professional standing and peer reviews).

A.Discovery of New Drugs, Concepts and Mechanisms of Action of Drugs from Ayurveda- (Serial no 92-112, drug discovery for details).

B.Significance of Work Done, Visionary Concepts, Recognition in Ayurveda- Details in Professional Standing.

26.RENOWNED INTERNATIONAL AUTHORITY AND CONSULTANT ON MEDICINAL PLANTS (PHARMACOGNOSY)

A.United Nations Consultant-UNDP, UNIDO. USFDA,FAO,WHO Etc

B.Consultant - International World Bodies, Universities, Organisations Etc

27. LISTED AMONG TOPMOST INDIAN PIONEER MEDICINAL PLANTS RESEARCHERS AND THINKERS IN NATIONAL JOURNALS

A.CURRENT-SCIENCE Ayurveda-scientific research and publications, NO-97, VOL-8/25-10-2009.

B.CURRENT SCIENCE -The quest for evidence based Ayurveda: lessons learned, VOL. 102, NO. 10, 25 MAY 2012.

C.J-AIM - A Renaissance for Ayurveda, J. Ayurveda. Integr Med. 2010 Jan-Mar; 1(1): 1–2.

28.LISTED AMONG TOPMOST PIONEER INTERNATIONAL RESEARCHERS IN INTERNATIONAL JOURNAL

A.CELEBRATED RESEARCHERS: SERIAL -7, Link natural products digest, vol. 6 issue 2, 2010, pg13.

29.UNITED NATIONS PROJECTS IMPLEMENTED INTERNATIONALLY

A.UNDP/UNIDO- HERBAL MEDICINES (VIETNAM).

B.WHO- BANGLADESH-MEDICINAL FORMULATIONS FOR GOVT OF BANGLADESH.

C.WHO- USA- CONSULTANCIES ALL OVER USA ON PLANT TOXICITY IN HUMAN FOODCHAIN.

30.BOOK RELEASED AT INDIAN PHARMACEUTICAL CONGRESS (IPC-DELHI-2008)-"HIV, Aids & Bioactive Natural Products” at event diamond jubilee celebrations).

31.MEDIA COVERAGE - Risorine release covered on DD news channel, borax plant covered on BBC news, medicinal awards in news, internet etc

 

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BACKGROUND

Prof. Dr C. K. Atal (1928- ) who is among one of the foremost internationally based multidisciplinary modern Pharmacognosists was born in Lahore, prepartition India on 4 November, 1928. He received the B. S. (B. Pharm 1949 batch from Medical College Amritsar) and his M. Pharm from Punjab University, Amritsar (later relocated to Chandigarh, India). His major/ Ph. D. degree was done from Connecticut University, USA in Pharmacognosy (study of medicinal plants) and his major advisor was world renowned Professor Arthur E. Schwarting. Dr Schwarting encouraged a multidisciplinary approach to science, research and teaching among student scholars and also changed the scenario in Pharmacognosy globally by introducing new revolutionary modern teaching concepts and modern scientific classification.

Under his advisor’s influence, Dr. Atal adopted this modern and multidisciplinary approach, which laid the foundation of significant internationally recognized multidisciplinary work done by him in his career. In 1957, he accepted a faculty position as Chairman at the University of Nebraska, USA, department of biosciences medical centre and obtained resident status (green card) in USA. However going against the trend of brain drain he returned to India in 1958 and continued his work in India and internationally, while based in India. In India, Dr. Atal also propagated and revolutionized Modern Pharmacognosy in research and teaching following on the footsteps of his guide and inspired a generation of scientists and students in pursuing the overlooked subject of Pharmacognosy in India. He also accepted several internationally based United Nations consultancies for several years.

INTRODUCTION

Professor Dr. C. K. Atal, an internationally based and reputed scientist, is renowned all over for his outstanding original contributions and pioneering work in a wide field of natural products, plant sciences and medicinal plant based disciplines. He is one of the uncommon multidisciplinary scientists, whose contributions have had major global impact in a wide variety of fields. He established a distinguished career having international scientific ramifications and impact, and his services have been sought by many major world organizations globally. He is one of the topmost “modern Pharmacognosists” of India, and in the words of Association of Pharmaceutical Teachers of India, “a distinguished pioneer of modern Pharmacognosy in India, who revolutionized Pharmacognosy as a subject, as a teacher and researcher in India,” at the first Prof. G. P. Srivastava award citation. Due to the multidisciplinary range and depth, particularly a rare combination of knowledge of two sciences, chemistry and botany, he has produced enormous research / publications (about 450 to 550 or more) in national and international journals. These include chemistry of natural products, essential oil bearing plants, fixed oils from plant and sources, survey screening of raw materials, introduction and experimental cultivation of plants, tissue culture studies, synthetic chemistry, and pharmacological investigations of plant principles. Having a workaholic nature and a capacity of speedy multi-tasking, he has produced enormous volume of significant work in many spheres of sciences.

He is an award winning visionary, multidisciplinary scientist, thinker, scholar, researcher, discoverer, drug developer, author, writer, teacher, guide, examiner and an excellent administrator all combined in one. Besides, his other qualities include being a multi linguist, historian, poet, artist, art patron, connoisseur, critic, and collector.

He has travelled internationally to about 30-35 countries including multiple visits as a mission consultant to numerous major world organizations like various UN organizations, British council. PAHO, OAU, USFDA, Governments of Burma, Bangladesh, Vietnam, West Indies, Africa, SAARC, USA, Soviet academy, Polish academy ,UK, France Germany and various international universities etc. He has been a member of several governing bodies constituted by the Government of India. He was a core member of the Indian advisory team of top four senior most directors and DG of CSIR, headed by Prime minister of India Mrs. Indira Gandhi on scientific matters.

He is a pioneer and a visionary who has remained well ahead of his time. He has introduced modern thoughts, technologies, discovered new revolutionary concepts, produced several significant drug discoveries, revolutionized Pharmacognosy in India on modern thoughts and established industries internationally as consultant. Institute RRL has several patents to its credit directly based on his works. He has immensely contributed to the socioeconomic status of India and also other countries by pioneering research and technology development leading to successful industrial benefit. He has several “first reporting in the world” in science. He has been a world authority on Crotalaria and its toxicity, produced serial publications on it, and was invited to USA as consultant for WHO, USFDA / PAHO (USA) on crotalaria, food adulteration and toxicity. He has written several books including world reference books used globally and used in post graduate teaching courses in Pharmacy colleges. He has been a very popular teacher and guide and produced forty PhD students which include distinguished students. He has been recognized as a PhD guide by the various Universities, while the Department of Chemistry, Jammu University has awarded him the honorary professorship. He has also been associated with teaching at USA (Associate Prof.) Nebraska and Connecticut, Punjab University, Chandigarh (as Head, Pharmacognosy), RRL Jammu (as Director) and also students of BITS, Pilani sent to RRL, Jammu.

As Director of institute RRL, Jammu, he transformed it into a modern internationally recognized multidisciplinary research institute which produced several award winning contributions and discoveries in a wide base of sciences. It became a landmark institute in the region, acquired one of the topmost positions among the forty laboratories of CSIR in India, and also got elevated on the international maps where significant work has been done. RRL became a leader in Biotechnology as well as one of the premier institutes in essential oils and aroma chemicals in India, being comparable to highest international standards. RRL achieved respect as a leader in research on medicinal /aromatic plants, its conservation, genetic improvement, development of herbal drugs, its quality control, standardization, industrial biotechnology, resolution of racemic drugs, fermentation technology, natural product chemistry, chemical technology, etc. Plant breeding, propagation, introduction of new species, domestication technology and other plant science brought fame to the institute and a big boost to the economy of the country. The very first Indian Ethnopharmacology team was launched at RRL in 1985 to preserve the threatened traditions of tribals. He has been on board of the prestigious international Journal of Ethnopharmacology, Ireland, published by Elsevier. Significant drug development research resulted in revolutionary path breaking discoveries and concepts like plant bioenhancers and plant immunomodulators for the very first time in the world. As a result the world’s first bioenhanced anti tubercular formulation “Risorine/kit” was dedicated to the Indian nation by science and technology minister of India and CSIR on world Tuberculosis day on 24th march 2011, who also presented the drug same day to Philanthropist Mr. Bill Gates (Chairman, Microsoft) as safer and economical TB drug for poor masses. Anti Urolithiatic drug Debilysin and anti arthritic drug Sallaki found international market (Byelorussia, Ukeraine, Europe and other countries). Apart from Rauwolfia discovered by Col. Sir R. N. Chopra in late forties, Sallaki (launched in 1982) became the second important scientifically proven single plant based major herbal marketed drug in India in five decades based on Indian system of medicine (Ayurvedic and Unani).

In pursuit of national goals for rural development, rural research and development yielded numerous revolutionary rural oriented programmes, significant socioeconomic rural benefits and resultant recognition and awards like FICCI award, UN award of grants and many other awards. Contributions in essential oils have significantly helped transform the socioeconomic status of the rural masses of India and essential oil industry of India as well as also internationally, like in Burma (Myanmar), Vietnam, and also by formulation of projects as UN consultant for Africa (UN projects). Efforts of RRL under Dr.Atal firmly established and economically transformed the Indian mint industry from being a minor to being a giant producer as we see it today, a sort of green revolution in mint in India(ably supported by other agencies in India too later) .This was achieved by widespread introduction of superior variety of Japanese mint along with development of technology for bold crystal of mint for first time in India. This was the first serious effort in India at such endeavor. Dr. Atal introduced the prized and expensive Hops successfully for the first time in India which established the first successful Hops industry in India with significant beneficial impact on imports. As a prominent member of Sadasivan committee, he helped to rescue/stabilize troubled Indian tea industry from stiff international competition by recommendations. Remote areas of India were provided with technology and development projects, like the innovative Borax extraction plant (PUGA valley project, Ladakh ,which was covered by BBC news) using innovative geothermal energy and also use of other alternate sources of energy by introducing solar dryers at Ladakh and Kargil. Anti Pollution and Environment conservation projects were implemented as early as the seventies and eighties, when awareness and concerns on the subject was much less. Examples include, use of environment friendly alternate sources of energy like geothermal energy (Ladakh) and solar energy (solar dryers) in the agriculture/rural industry. Pollution /waste management projects like conversion of forest waste into utilizable end products (Himachal government pine needle fiberboard project, the first of its kind in the world,) were implemented. Similarly conversion of manmade waste into useful animal feed prevented environment pollution (apple pomice project, river Jhelum, Kashmir, horse division of army) with added economic and employment benefits. Munchen (Munich) University invited him as a solar energy consultant. Introduction and large scale promotion of fast growing tree species in the rural belts facilitated and encouraged mass forestation. Socioeconomic, educational, scientific and humanitarian events were held by the institute for the masses focusing on superstition, modern science, training workshops, education, science and technology, research benefit, targeting all strata of society like institutions, individuals, women, rural, small scale and others. In 1971, emergency blood donation camps for war casualities, evacuation sorties for stranded civilians at Akhnoor border, Jammu, followed by post war Army welfare benefit event were held.

As United Nations consultant, he successfully formulated and implemented multiple multimillion US dollars projects in south East Asia with time bound precision and within budget. Several UN consultancies (UNIDO, WHO, BRITISH COUNCIL etc) in several countries (Trinidad, Tobago, Vienna, Vietnam, USA, Africa and Bangladesh) led to successful socioeconomic impact in those countries. The multidisciplinary competent performance at RRL finds mention in the United Nations recommendation letter from head office Geneva, justifying awarding these multiple UN projects simultaneously to Dr. Atal, a rare occurrence in view of concerns of risk of failure and enormous expenditure at stake involved in the projects.

He has been an able and competent administrator with legendary trouble shooting habits and instincts. He has been a dominant leader in all endeavors, scientific or extracurricular, as head of the institute or as consultant to major organizations. He has helped the distressed and always encouraged hard work and talent. In the words of his colleagues he has been a colossus of a human being.

 

CHAIRMAN, ASSOC . PROF GRADE, MEDICAL CENTRE, BIOSCIENCES DEPT , JESUIT CREIGHTON UNIVERSITY, OMAHA, NEBRASKA, USA

 

HONORARY PROFESSORSHIP UNIVERSITY OF JAMMU, CHEMISTRY DEPT, INDIA

 

HEAD, DEPARTMENT OF PHARMACOGNOSY, UIPS, PANJAB UNIVERSITY, CHANDIGARH, INDIA

 

DIRECTOR RRL, JAMMU, KASHMIR, (NOW CALLED IIIM) CSIR , INDIA , 1ST DIRECTOR OF CSIR COMPLEX ( IHBT) , HIMACHAL, INDIA

 

UNITED NATIONS CONSULTANT-, UN HEAD OFFICE , - GENEVA AUSTRIA (CHEMICAL TECHONOLOGIST)UNDP , UNIDO,

 

UNITED NATIONS CONSULTANT - HEAD OF UN PROJECTS OF SOUTHEAST ASIA IN VIETNAM (CTA)

 

CONSULTANT TO OTHER UNITED NATIONS ORGANISATIONS (WHO, FAO, ETC ) - USA , AFRICA BANGLADESH

 

MISSION CONSULTANT TO SEVERAL WORLD BODIES, UNIVERSITIES, INSTITUTIONS , ORGANISATIONS ETC

 

DRUG DISCOVERY BASED MEDICINE RELEASED BY INDIAN GOVT. ON WORLD TB DAY 2011 AND PRESENTED TO WORLD DIGNITARY MR. BILL GATES OF MICROSOFT

 

INTERNATIONAL BASE FOR SEVERAL YEARS IN USA ,VIETNAM,

 

OTHER SHORT INTERNATIONAL CONSULTANCIESINTERNATIONAL STANDING -

 

VISITED 30-35 COUNTRIES FOR CONSULTANCIES, ADVISORY, LECTURES ETC

 

WORLD AUTHORITY ON CROTALARIA AND IT’S TOXICITY. CONSULTANT TO USA, UN ,WHO, PAHO, USFDA FOR CROTALARIA AND OTHER FOOD ADULTRATIONS

 

MEMBER OF GOVERNING BODIES, GOVERNMENT OF INDIA, CONSULTANT CSIR DELHI.

 

MEMBER OF SEVERAL SCIENTIFIC SOCIETIES/ PRESIDENT OF ASSOCIATIONS

 

ESTABLISHED RRL JAMMU AS WORLD CLASS PREMIER INSTITUTE IN ESSENTIAL OILS , BIOTECHNOLOGY , PLANT SCIENCES, DRUG DEVELOPMENT

 

SEVERAL AWARDS , HONORS AND RECOGNITION IN MULTIDISCIPLINARY FIELDS

 

AUTHOR , WRITER , EDITOR OF SEVERAL BOOKS, UN COMPILATIONS INCLUDING TWO WORLD REFERENCE BOOKS

 

ENORMOUS MULTIDISCIPLINARY RESEARCH PUBLICATIONS IN NATIONAL AND INTERNATIONAL JOURNALS IN SEVERAL FIELDS ON EDITORIAL BOARD OF INTERNATIONAL JOURNAL, ELSEVIER

 

DISTINGUISHED TEACHER, EXAMINER & GUIDE - PRODUCED 40 PhD STUDENTS INCLUDING DISTINGUISHED SCIENTISTS , AWARD IN TEACHING,STUDENT IN USA

 

SEVERAL FIRST REPORTINGS IN WORLD ON SCIENCESEVERAL FIRST REPORTINGS IN INDIA

 

MULTI DISCIPLINARY SCIENTISTMULTI-TASKING

 

VISIONARY PIONEERING WORK IN PHARMACEUTICAL SCIENCES

VISIONARY PIONEERING WORK IN AYURVEDA,

LISTED IN TOP PIONEER RESEARCHERS OF INDIA IN CURRENT SCIENCE, NO 97, VOL 8, 25 OCT 2009 AND ELSEWHERE

 

VISIONARY AND PIONEER -

 

SIGNIFICANT CONTRIBUTIONS IN SCIENCE & TECHNOLOGYAPTI AWARD FOR REVOLUTIONISING PHARMACOGNOSY AS A SUBJECT IN INDIA

BASKET OF DRUGS DISCOVERED, RESEARCHED, DEVELOPED AND LEADING TO MARKETING IN INDIA & INTERNATIONALLYDISCOVERY OF NEW REVOLUTIONARY DRUG CONCEPTS (PLANT BASED BIOENHANCERS AND PLANT IMMUNOMODULATORS FROM RASAYANAS IN AYURVEDAWORK ON OTHER TRADITIONAL HEALING SYSTEMS, ETHNOPARMACOLOGYPLANT SCIENCES LIKE ECONOMIC PLANTS, MEDICINAL PLANTS, AGRICULTURAL PLANTS, FRUITS, ESSENTIAL OIL PLANTS, FRAGRANCES, DYES PIGMENTS, PERFUMERY, AROMA CHEMICALS ETC

AWARD WINNING RURAL DEVELOPMENT WORK (INDIA AND ALSO INTERNATIONALLY),FICCI AWARD ON RURAL DEVELOPMENT GIVEN BY PRESIDENT OF INDIA EDUCATION OF SOCIETY -REMOVAL OF SUPERSTITION, EDUCATION OF SOCIETY ON SCIENCE , WORKSHOPS ON SCIENCEDEVELOPING REMOTE AREAS OF INDIA –THROUGH R&D

R&D FOR THE BENEFIT OF POOR AND ILL POPULATIONENVIRONMENT CONSERVATION -FOREST AND INDUSTRIAL WASTE MANAGEMENT AND ITS CONVERSION INTO USEFUL PRODUCTS

POPULARISING ALTERNATE SOURCES OF ENERGY,FAST GROWING TREE SPECIES CONTRIBUTIONS IN NON WOOD FOREST PRODUCTS , MINOR FOREST PRODUCTSFORMULATING PROPOSALS AND IDENTIFICATION OF VIABLE PROJECTS IN DEVELOPING COUNTRIES INTERNATIONALLY (UN) AND IN INDIAESTABLISHING FIRST ETHNO PHARMACOLOGY CENTRE IN INDIA, FOR BENIFIT OF TRIBALS, TRADITIONAL METHODS

SOCIOECONOMIC DEVELOPMENT OF INDIA THROUGH ESTABLISHMENT OF SEVERAL SUCCESSFUL INDUSTRIES AS A CONSULTANTSOCIOECONOMIC DEVELOPMENT INTERNATIONALLY THROUGH ESTABLISHMENT OF SEVERAL SUCCESSFUL INDUSTRIES AS UN CONSULTANT ESTABLISHING MULTI MILLION DOLLARS UN INDUSTRIES INTERNATIONALLY AS CSIR AND UNITED NATIONS CONSULTANT / PROJECT HEAD

 

ESTABLISHING NUMEROUS INDUSTRIES IN INDIA AS CONSULTANT , CONTRIBUTIONS IN REVOLUTION OF MINT AND HOPS INDUSTRY IN INDIA

 

SOCIAL SERVICE , FOR WAR VETRANS/ WIDOWS, BLOOD DONATION CAMPS , PARTICIPATED IN FREEDOM STRUGGLE AS A TEENAGER EXCELLENT ADMINISTRATOR AND AN EXCELLENT HUMAN BEING

 

COMMENDABLE PEER REVIEWSFECILITATED BY SCIENTIFIC COMMUNITY, DISTINGUISHED SCIENTIST OF INDIA

 

COMMENDABLE PEER SCIENTIFIC REVIEWSORIGINAL RESEARCH ON ART & HISTORY , MULTILINGUIST, ART CRITIC AND COLLECTOR, MANY EXTRACURRICULAR ACTIVITIES

 

 

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Ladies are usually much more conscious regarding their body photo as well as weight as compared to guys - and that is why women are typically the targets of deceitful fat burning approaches as well as products. Media's representation of pencil-thin models and starlets do not assist. In fact, this unhealthy idealization of slimness harbors harmful eating practices as well as crash diets.

 

Healthy and balanced weight loss for ladies

 

As a woman, you must comprehend is that in order to attain a really healthy body, you should begin and follow up a program that promotes healthy weight-loss for females. Such programs do not guarantee instant fat burning - just what you obtain instead is steady but lasting renovations in your body. Avoid eating disorders and other possible issues by sticking to healthy and balanced fat burning for women.

 

Comprehending weight management

 

Medically, weight loss is the procedure of reducing weight with decrease of body fat. Fat burning is typically recommended to obese individuals and to those that are obese. Excessive weight can be gauged through one's body mass index (BMI) or the percentage of one's weight to her height.

 

There are 2 methods of reducing weight: purposefully and unintentionally. Intentional weight loss entails a conscious effort to slim down. Various weight management techniques include dieting, exercise, and weight-loss items such as diet tablets and also patches. For extreme weight management, one can go through surgical treatment in clinics.

 

Unintentional weight loss, on the other hand, is normally an outcome of sickness. It happens if you are enduring - or have experienced - an extreme body issue or disease. Unintended weight reduction generally results from illness such as cancer, diabetic issues, and also various other metabolic issues.

 

Comprehending the 'suitable' body for females

 

The primary step to healthy fat burning for women is establishing a realistic and healthy and balanced objective. There are clinical and also medical standards to help you determine your suitable body weight. Below is the excellent weight variety for ladies according to different elevations.

 

Elevation (ft/inches) Suitable Weight (Pounds).

 

5' 0" 97-127.

 

5' 1" 100-132.

 

5' 2" 103-136.

 

5' 3" 107-140.

 

5' 4" 110-145.

 

5' 5" 113-149.

 

5' 6" 117-154.

 

5' 7" 121-159.

 

5' 8" 124-164.

 

5' 9" 128-168.

 

5' 10" 132-173.

 

5' 11" 135-178.

 

6' 0" 139-183.

 

What you shouldn't do.

 

1. Accident diet programs and also fad diets. Research studies have revealed that crash diets or empty-calorie diet plans are inefficient as well as could only result in weight gain in later years. Fad diets also do not work in the future, often leading to significant difficulties if performed incorrectly. Thus, a healthy weight management program for women is the excellent service to weight issues.

 

2. Un-reviewed diet items. Diet pills and diet regimen patches are several of the products being marketed rampantly and honestly out there today. Nevertheless, the USFDA has asserted that numerous of these medicines have not undergone rigorous testing by the federal government. Hence, the long term results of these items are still unidentified. Customers are asked to take these products with careful consideration and not quickly fall prey to ad cases and unethical customer reviews. Keep in mind that some of these drugs need no prescription and can be acquired by any individual - at any type of age.

 

The right way: Healthy weight reduction for females.

 

The only healthy and balanced fat burning program for females is this: appropriate diet plan and also workout. There are no short-cuts to slimming down. Ingesting diet regimen pills and using diet plan patches might work in the temporary, yet there are no adequate studies to recognize the long term effects of these items. Additionally, researchers are also still unaware of the side-effects of these products.

 

When losing weight, bear in mind to remember that being too skinny does not always relate to being healthy. Falling listed below your excellent body mass index can be harmful.

 

Consult with a professional.

 

To start a healthy weight-loss program for women, first speak with a specialist. Talk to a nutritionist or dietitian. They can help you recognize about your body as well as your weight. He can also provide you appear advice on what weight management methods you can adapt to help you slim down the healthy way.

 

Cut down on calories.

 

The next step to a healthy weight management for females is to cut down on the quantity of food you consume. Lowering calories and also other convenience food will assist you bring down your weight as well as live a healthier way of living. A few of the foods you ought to obtain free off include:.

 

1. Changing soft drinks as well as sodas with water.

 

2. Exchanging entire milk for semi-skimmed, or semi-skimmed for skimmed.

 

3. Eating much less lunch than typical.

 

4. Lowering the intake of sugar in tea and coffee.

 

5. Having smaller sections of the food you enjoy.

 

6. Staying clear of 2nd helpings at supper.

 

7. Removing harmful treats such as confectionery, sugary biscuits as well as crisps between dishes.

 

8. Cutting down on beer and also alcohol.

Eat more corn, oats and rye products - fish and poultry - fruits, vegetables and potatoes

Baked, boiled and broiled foods

Eat less wheat, meat, sugar and fats

To save for the army and our allies

Without choosing a painful method with different types of circumcision cuts, the specialized surgeons perform treatments that are USFDA approved and are advanced as well as affordable. Laser surgery is considered one of the best methods for circumcision surgery as it is almost pain-free, scar-free, with no cuts and sutures required. The recovery time to heal is also less as compared to other methods of circumcision. With just 30 minutes of surgery, the patient can get discharged within one day and can resume back to their normal life with ease. The various benefits that come with this method make it an effective way to get rid of your foreskin.

 

For More Information Visit:

glamyohealth.in/blog/types-of-circumcision-cuts

 

Please do not support genetically modified salmon We should not mess with mother nature

World's First & Only Prestigious USP Grade Spirulina

 

Made wholly from premium, certified organic spirulina from Parry Nutraceuticals Ltd., India, a distinguished manufacturer specializing in organic spirulina cultivation and actively involved in spirulina research all over the world. The only spirulina in the world to be awarded the prestigious USP Grade. 100% natural, without fillers, binders or chemical additives for greater absorption and better nutrient assimilation.

 

USP (United State Pharmacopoeia) Certification - The Ultimate In Quality Assurance

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quality Parry Spirulina Trusted Worldwide For Quality & Safety

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(Japan Health Food Authorization) & European Health Food Standard

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• Strict Quality Control & Assurance

• Scientifically & Extensively Researched

 

Spirulina's All-Around Health Benefits

• Strengthens the immune system •Maintains cardiovascular health & lowers

cholesterol

• Improves gastrointestinal & digestive health •Protects against anaemia

• Helps weight control • Promotes healthy, vibrant skin • Enhances natural cleansing

& detoxification

 

Price - RM 28 (120 tablets) each

RM 65 (300 tablets) each

promo price - Buy 2 items and get 50% off for third item (RM 17) - 120 tablets

promo price - Buy 2 items and get 50% off for third item (RM 35) - 300 tablets

 

Payment:

- All orders pay by cash to maybank account

(112317104818 - Patricia) Cosway Distributor

- Proof of purchase email to onlinevipshopper@yahoo.com

- Also send a notisfication by sms to 012-2277141

- Rm 50 and above will get a mistery gift for free

 

Courier fees:

- Below 2 items RM 12

- 3-5 Items RM 18

- Above 6 items RM 25

 

Courier office : Skynet

1957 Dr C K Atal DINEEN STUDIO,USA

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(4) www.niscair.res.in/sciencecommunication/researchjournals/...

(5)ignca.nic.in/nl002103.htm

 

INTERNATIONAL CONTRIBUTIONS

41.INTERNATIONAL BASE – He has resided in USA (1954 to 1958) as a US resident (status green card), worked as Chairman/associate Professor grade at Nebraska, USA, and migrated to Indian citizenship, going against the trend of brain drain. He has worked for about 8 -9 years internationally as UN consultant (including 7 years in field south East Asia, base Vietnam, 1985 - 92). He has extensively travelled to 30-35 countries internationally as UN consultant, as CSIR consultant or mission consultant to major organizations in countries in Asia, SE Asia, Europe, USA, Africa etc.

42.INTERNATIONAL CONSULTANCIES-(Serial no 43-65, MISSION CONSULTANT to world organizations, also See countries traveled Serial no 68). The various scientific interactions are for Eli Lilly-USA, Polish Academy of Sciences, British Council, Organization Of African Unity (OAU), West Indies, Burma Government, Vietnam Government, Bangladesh Government, Pan American Health Organization (PAHO), USFDA, Soviet Academy of Sciences, University of Texas, USA (lecture at Pharmaceutical Sciences department), UK University of Exeter (Commonwealth Foundation, Univ. Grants Commission), University of Munchen, Germany, SAARC scientific conference (Sri Lanka), France, Bulgaria etc.

43.UNITED NATIONS INTERNATIONAL CONSULTANCIES- See details in mission consultant, UN Passport records (laissez passer).

A.WHO (Bangladesh), WHO (USA), FAO (non wood forest products), APPOINTED/SELECTED FOR UN PROJECT IN AFGHANISTAN (project postponed for technical/safety reasons due to instability in the region), UN HEADQUARTERS (VIENNA, AUSTRIA) for formulating UN projects in Vietnam,UNITED NATIONS -AFRICA (for identifying viable projects in Africa),

B.UNDP, UNIDO-VIETNAM - five United Nations projects costing approximately about 10 to 13 million US dollars.

•HERBAL-MEDICINES.

•ESSENTIAL-OILS.

•DYES-&-PIGMENTS.

•AROMA-CHEMICALS.

•HIGH VALUE ROSIN & TURPENTINE.

MISSION CONSULTANT TO MAJOR INTERNATIONAL WORLD ORGANISATIONS

CONSULTANCY, ADVISOR, PROJECT LEADER, IDENTIFYING AND IMPLEMENTING PROJECTS, TECHNOLOGY DEMONSTRATION, SCIENTIFIC INTERACTION, FELLOWSHIP, LECTURES, CHAIRING INTERNATIONAL CONFERENCES ETC

44.USA (1957-58,) - ELI LILLY SUMMER FELLOWSHIP, USA - on selection & development of high yield strains of Clavicaps purpurea and submerged culture of Clavicaps purpurea .Other visits in 1974, 1981, 1992, 2004.

45.USA,National science foundation,1974-two months

46.POLAND (Nov,1972) – POLISH ACADEMY OF SCIENCES/ INSTITUTE OF ORGANIC CHEMISTRY - headed by the Polish Director, Dr. Kocor (pronounced as kochur) invited Dr. Atal for lecture (Chemistry of Natural Products) & technology demonstration in several institutes of Poland in 1972. www.flickr.com/photos/13059662@N06/6506006811/

47.WEST INDIES- CARRIBEAN AREA (1979) - (expert on behalf of COMMON WEALTH RESEARCH COUNCIL-BRITISH COUNCIL, TRINIDAD TOBAGO)-, Distillation techniques & technology demonstration, lectures, introduction of lemon grass oils etc.

48.GERMANY (UNIVERSITY OF MUNCHEN /MUNICH)-(Nuclear research institute) invited Dr. Atal as a solar energy consultant, visited Germany in 1978 & 1985.

49.FRANCE (1980) - STRASBOURG INTERNATIONAL RESEARCH CONGRESS -to chair the international conference “International Research Congress on natural products as medicinal agents”, on July, 6-12, 1980.

50.BULGARIA (1981) - SOFIA INTERNATIONAL CONFERENCE, -to chair a session on the international conference on “Chemistry and Biotechnology of biologically active natural products” and Rose oil, on 22 Sept, 1981.

51.GREECE-delivered a special lecture at international symposium on Aromatic plants.

52.BURMA (1981) – GOVERNMENT OF BURMA (Rangoon), (presently Myanmar): To set up Menthol distillation plant , transfer of technology for production of bold crystals of Menthol from Mentha arvensis, setting up a menthol pilot plant & demonstration unit (Menthol extraction plant) and training techniques. The Pharmaceutical research Department of Central Research Organization (CRO), Burma was provided Diosgenin – Progesteron plant at Hmaw-Bi, Rangoon. www.flickr.com/photos/13059662@N06/6824106944/in/photostr... www.flickr.com/photos/13059662@N06/6970421821/in/photostream

53.USA (Oct 1981) FOUR WEEKS –He was appointed as international consultant to USA in his capacity as one of the leading world authorities on Crotalaria.

A.WHO (WORLD HEALTH ORGANISATION)- World Health Organization was the primary agency to appoint him as WHO expert consultant on toxicology, particularly on Crotalaria and its toxicity and sent him to USA as consultant to other agencies.

B.USFDA (BUREAU OF FOODS, US FOOD & DRUG ADMINISTRATION) – USFDA-Division Of Toxicology as consultant on toxicology, for division of chemistry and physics, & division of toxicology, bureau of foods, USFDA , regarding toxicity studies / human toxicity particularly by Crotalaria mixed in food chain/ Pyrrolizidine alkaloid containing seeds.

C.PAHO (PAN AMERICAN HEALTH ORGANIZATION) - WHO appointed him as consultant on toxicology for PAHO as well as USFDA simultaneously.

54.RUSSIA AND TASHKENT, (1981) - Soviet academy of sciences: invited Dr. Atal for lecture and technology demonstration.

55.WORLD HEALTH ORGANISATION

A.USA CONSULTANCY - as noted above.

B.BANGLADESH CSIR- as noted below.

56.SELECTED FOR UN PROJECT IN AFGHANISTAN (around 1983-84) –due to prevailing instability, project was suspended/postponed for safety reasons.

57.BANGLADESH GOVERNMENT (1984) - for helping Bangladesh CSIR, for technology demonstration to upgrade/modernize their Pharmaceutical formulations, like Chavanprash. (See NEXT HEADING-WHO below).

58.WORLD HEALTH ORGANIZATION (WHO) 1984 – (Refer to Bangladesh Govt. Above) appointed him as consultant to help establish technology institutes for Bangladesh Govt. (CSIR). (See above topic).

59.UNITED KINGDOM (1984) -University of Exeter (Commonwealth Foundation / University Grants Commission) invited Dr. Atal for lecture tours. A Holland tour also was included in this tour.

60.UNITED NATIONS (VIENNA, AUSTRIA) (1984 /85) for identifying projects in developing countries like South East Asia, Vietnam. Project was handled by Mrs. Cheknovorian who offered Dr. Atal to implement these projects in Vietnam as UN chief consultant and which was soon accepted by Dr. Atal.

61.UNIDO/UNDP,VIETNAM ( BASE S. E. ASIA - seven years, 1985-1992)- For peer reviews on UN contributions by a distinguished international UN consultant, www.flickr.com/photos/13059662@N06/5737077185/in/photostream Dr. Atal was Chief technical advisor (Chemical Technologist in UN roster) for five projects funded by United Nations costing about 11-13 million US dollars implemented and commissioned in Vietnam ( field area South East Asia). He implemented the projects successfully, on time schedule and within budget.

•PROJECT-DP/VIE/80/032-HANOI-VIETNAM,(HERBAL-MEDICINES).

•PROJECT-DP/VIE/84/010-HANOI-VIETNAM,(ESSENTIAL-OILS).

•PROJECT-DP/VIE/85/001-HO CHI MINH CITY-VIETNAM(DYES & PIGMENTS).

•PROJECT-DP/VIE/86/033-HO CHI MINH CITY - VIETNAM(AROMA CHEMICALS).

•PROJECT-DP/VIE/TECHNOLOGY FOR HIGH VALUE ROSIN & TURPENTINE. This resulted in high quality production of several natural plant based products, with huge socioeconomic and industrial benefit. The projects were successful socioeconomically. For example, in the very first year of its production, the sales of Eucalyptus oil crossed the million dollar mark in international market due to its strict quality control. Other examples include Bixa orellana (butter yellow) Berberine factories, Curcumin/ turmeric factory, dyes, essential oils, aroma chemicals, cultivation techniques, field’s establishment, and many other projects. More projects were offered to him but he returned to India

62.VIETNAM GOVERNMENT (1985-1992) Institutes of Vietnam ,examples like Institute of Materia Medica (Hanoi) headed by Madam Knu were upgraded with latest technology and scientific infrastructure at both Hanoi and Ho Chi Minh, all funded by UN. (Serial no 42, UNIDO/UNDP 1985-1992). He developed large cultivation farms and factories for medicinal and aromatic plants at Saigon (Ho Chi Minh City), for projects like berberine from Berberis, curcumin from rhizomes of Curcuma longa / haldi and many other projects for Vietnam government. . (See above topic).

63.USA-HOUSTON TEXAS UNIVERSITY (1992) - Dept. of Pharmaceutical Sciences for lecture on biologically active molecules at the University institute.

64.POLISH HERBAL PHARMACEUTICAL COMPANY “HERBAPOL” (post 1992) for identifying joint ventures with India, complimentary task.

65.UN - AFRICA CONSULTANCY-- FOR UN PROJECTS (1993) –See OAU BELOW www.flickr.com/photos/13059662@N06/6506000399/

66.AFRICA-ORGANIZATION OF AFRICAN UNITY (OAU-1993) - to help in development of Africa by formulation of United Nations funded developmental projects in Africa, Mozambique, Swaziland, and Maputo.(see above topic).

67.UNIDO / FAO (FOOD AND AGRICULTURE ORGANIZATION) PROJECT - ON NON WOOD FOREST PRODUCTS - SIX MONTHS PROJECT FOR, UNITED NATIONS (1994) (FAO UN PROJECT TF/GLO/94/009/11-01) –assigned as international expert to prepare UN project lead paper /keynote address on non wood forest products for “International Symposium on Forestry” on occasion of World forestry day at Djakarta, Indonesia. The compilation is published by UN/FAO-Viale dells Terme di Caracalla, 00100 Rome, Italy. (International Expert Consultation on non wood forest products, 1995), article 4.2.1 (Processing, refinement and value addition of non wood forest products –T. De Silva and C.K. Atal)).

A.http://www.fao.org/docrep/v7540e/v7540e00.htm

B.http://www.fao.org/docrep/v7540e/V7540e18.htm

68.SAARC SCIENTIFIC CONFERENCE (COLOMBO, SRI LANKA)–MEMBER OF INTERNATIONAL DELEGATION OF EXPERTS FROM SAARC COUNTRIES HELD AT SRI LANKA , 1995- international experts scientific conference of SAARC countries at SAARC Colombo scientific Conference held in 1995,third week of October.

OTHER SIGNIFICANT INTERNATIONAL CONTRIBUTIONS

69.WORLD AUTHORITY ON CROTALARIA –

A.Solving the outbreak of mysterious Phoolan bimari disease (epidemic of swelling of body in Sarguja district in Madhya Pradesh, India). Several teams investigated this baffling disease, including All India Institute of Medical Sciences, New Delhi. It was being attributed to some new disease of infectious etiology. This was solved by Dr. Atal when the cause was suspected and subsequently found to be toxicity by crotalaria seeds as food adulterant .It was covered in the national news. A team under Dr. Prabhay Singh Jamwal was deputed to the affected area with the instructions to collect all weeds in the fields particularly focusing on suspect Crotalaria. The team returned with several specimens but was unable to find Crotalaria. However on closer scrutiny the rogue plant was identified by Dr. Atal based on examination of unusually tiny but typical seeds of the plant among the sample specimens brought. Further research confirmed the toxicity due to Crotalaria plant.

B.Numerous serial research publications on Crotalaria have been published.

C.On the basis of these numerous publications , WHO appointed Dr. Atal as expert on Crotalaria toxicity and deputed him as consultant to USA, (Oct, 1981) for division of Chemistry and Physics and Division of Toxicology, Bureau of Foods, Food & Drug Administration (FDA) USA / and Pan American Health Organisation (PAHO-USA). Dr. Atal then conducted several lecture tours all over USA (wherever Toxicology work was going on) for toxic plant residues and adulteration in foods and cereals, isolation, detection of hepatotoxins in food chain, especially Crotalaria toxin which had caused morbidity / mortality in USA.

70.INTERNATIONAL IMPACT OF WORK-. Dr. Atal, a student of internationally acclaimed Pharmacognosist Prof. A.E. Schwarting (USA), has been one of the leading International multidisciplinary Pharmacognosists. He was a based internationally as green card US resident and as UN consultant for several projects internationally for about 12-13 years. He served as international multidisciplinary consultant to numerous major international organizations, world bodies, several countries and several United Nations organizations. Multiple multimillion US dollars UN projects successfully implemented/formulated by him have resulted in significant international socioeconomic benefits for the developing world like Vietnam. His drug development projects (Serial no 92-104, drug discovery) include internationally marketed formulations like Sallaki by Gufic (India, Europe, other countries) and Debelysin by Herbapol (Ukraine, Byelorussia, Poland etc). He has several “first reporting’s in the world” and new pioneering concepts in science, like discovery of plant immunomodulators (from rasayanas) and concept of bioenhancers in medical science. It has led to official launching of world’s first bioenhanced TB drug Risorine on world TB day 2011, which was also presented to world dignitary Mr. Bill Gates (Chairman, Microsoft), by Government of India at Delhi. As a world authority on Crotalaria he was invited as consultant to USA (by USFDA, PAHO, WHO) on Crotalaria toxicity. He has also held many international patents. He has also taught internationally in department of biosciences, Nebraska, USA and U. Conn, USA. His international reference books are inevitably found in libraries globally in plant research institutes and extensively quoted internationally in research studies. These are also used in post graduate Pharmacy teaching institutes all over India (refer author writer). His numerous research articles in prominent international journals are also extensively quoted internationally as references. He has been on panel of the prestigious “International Journal of Ethno-Pharmacology”, by Elsevier, Ireland. (Serial no 184-211, author, writer).He has delivered lectures in several countries, chaired international conferences and his UN compilation was presented on world forest conference at Indonesia.

COUNTRIES TRAVELLED FOR INTERNATIONAL INTERACTIONS

71.COUNTRIES TRAVELLED- Conferences, Consultancies, Lectures, Advisory, Collaborations, Travel tourism –(about 30-35 countries travelled, in alphabetical order, passport data) are Austria /Vienna-(1983, 1984, 1986, and more visits), America (USA-1954-57, 1974, 1981, 1992, 2004), Africa, Mozambique , Swaziland, Maputo, Britain (1974,1984, 1979,1992), Bulgaria / Sophia-For Rose Oil,(Sep, 1981), Burma/Rangoon(Myanmar)-(1981), Bangladesh (1984), Belgium (1958) , Canada (1974, 2004), Czechoslovakia (1978, 1981, 1993), Cambodia / Ankorwat (1992), Egypt /Cairo-Port Said-(1954), France (1980) , Greece (1981), Germany / Munchen, Deutschland-(1978, 1985), Hungary / Budapest (1972), Hong Kong (1986, 1988), Holland (1978, 1984, 1985),Italy, Indonesia / Bali, Djakarta , Jogjakarta(1992), Lebanon , Macau (Portugal Island 1988), Marseilles /Azure Blue Coast, Philippines /Manila – (1991), Poland (1972, 1978, 1981, 1993) Pakistan- (Place Of Birth), Rome, Sri Lanka (1995), Singapore (1987, 1992), Sudan, Switzerland (1993), Tashkent, Thailand - (Multiple Visits) ,USSR / Tashkent (1981), Vietnam (Multiple), West Indies (Trinidad And Tobago-1979),Andaman Nicobar islands(India).

72.INTERNATIONAL LECTURE TOURS, KEYNOTE ADRESSES Examples include lectures in five cities and various institutes of Hungary / Warsaw, Poland on invitation from Polish academy of Organic Chemistry headed by the Director Dr. Kocor, (pronounced kochur),lecture on biologically active molecules in 1992 in Houston University, Department of Pharmaceutical sciences, Houston, Texas, USA on invitation by Dr. Vishnu Das Gupta of same department, lectures in Vietnam (Hanoi and Ho Chi Minh) and in 1991 he accompanied Vice Minister, Ministry of Health, Vietnam Government, on a trip to India on educational, scientific tours. On 7th Feb 1991, he was a resource speaker on fractional distillation of essential oils with Mr. Salvador Fanaga and Mrs. A. Punruckvong at the Second UNIDO workshop on essential oil industry at Manilla, Philippine. He conducted several lectures in USA, Germany, UK, USSR, France, and West Indies (on essential oil distillation technology and solar drying). SEMINARS – he has organized, attended, participated and lectured in national and international seminars. Dr. Atal’s compilation/monograph on non wood forest products under UN consultancy was presented as a key note address on the World Forestry conference at Indonesia (delivered by Silva). He delivered keynote address at RRL, Jammu on event of Workshop on Radioimmunoassay, silver jubilee celebrations of RRL, Jammu, Dec, 1-6, 1982, inaugurated by Prof. J. S. Bajaj, HOD (Medicine), AIIMS, Delhi, and delivered keynote address on the first National symposium on Survey and Cultivation of edible mushrooms in India, the welcome keynote address was delivered by him. Jamia Hamdard, 2003 - Delivered keynote address at ‘Pharmacy week’ in Nov 2003 at Jamia Hamdard (newsletter , Jamia Hamdard “spreadsheet” march 2004 issue) –Theme of the week was “Pharmacists for the promotion of future free of Tobacco(page 2 Para 2- flashback). www.jamiahamdard.edu/PDF/News%20Letter_JH.pdf He has delivered multiple lectures on History of India, particularly Punjab history.

  

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Website: - www.oxygen-absorbers.com/oxygen-absorber-packets/

 

I would really love if you could help stop the genetic modifing of salmon.

Sensex & Nifty firm, Midcap up 1%; Sun Pharma drops 4%

  

The BSE Midcap and Smallcap indices climbed 1 percent each. About three shares advanced for every share declining on the Bombay Stock Exchange.

  

Mahesh Nandurkar, CLSA says the government has started laying out building blocks for a sustainable higher growth trajectory for India. “We highlight 4 key initiatives i.e financial inclusion, digital India, improved foreign policy and greater autonomy to states. While these initiatives do not have a quantifiable economic impact; they will have a huge broad based positive impact for an inclusive longer-term growth improvement,” he adds. 10:00am The market continued to trade in a positive terrain with the Sensex rising 44.85 points to 27102.26 and the Nifty gaining 19 points to 8113.10 while the broader markets outperformed benchmarks smartly. The BSE Midcap and Smallcap indices climbed 1 percent each. About three shares advanced for every share declining on the Bombay Stock Exchange. Sun Pharmaceutical Industries fell over 4 percent on US drug regulator's surprise audit at the pharma major's Halol facility in Gujarat. It is learnt that USFDA inspectors in two teams are auditing both the injectibles as well as oral solids units at the plant, with one team focusing on manufacturing processes and other closely auditing quality control and assurance departments. In the midcap space, GSFC shot up 13.4 percent followed by Abbott India, Bhushan Steel, Indian Bank and Bharat Electronics with 4-5 percent while among smallcaps, HOEC, Oscar Investment, Infinite Computer, Punjab & Sind and Marathon Realty surged 9-17 percent.

Breast implant surgery is an excellent option to achieve youthful breast profile. In this treatment, silicone implants are inserted into the breast to restore lost volume and shape. The treatment can also be used to correct congenitally small breasts and other breast asymmetries. Based on individual body anatomy and profile, the implants are used to offer the best outcomes. Dr. Mrinalini Sharma is an expert Plastic and Breast Enlargement Surgery in Delhi at Aestiva Clinic. She uses the best quality implants that are USFDA approved and the latest techniques are applied to minimize downtime and optimize the results. For more information about Breast Implant Cost in Delhi, visit today at Aestiva Clinic.

 

For more details: Breast Reduction in Delhi

 

Contact: +91 8447652698

Email: info@drmrinalinisharma.com

Address: Saket Clinic E 33, Paryavaran Complex, IGNOU Road, Neb Sarai, New Delhi - 110030

 

Disclaimer:- Content and images on this post are for information purposes only.

 

Carmelo Rosa (USFDA, Division Director, CDER-Office of compliance; Chairman of the API expert circle coordinating committee)

 

Photo : Sandro Weltin/©Council of Europe

Harsiddh Engineering is a pioneer in manufacturing injectable pharmaceutical machines including washing machines, sterilizers, filling machines for liquid and powder, capping and lableling machines etc. The company is ISO 9001:2000 certified and active member of Engineering Export Promotion Council of India. We follow the competitive international standards USFDA/UKMHRA/WHOGMP to develop and retain the quality products what the clients are expecting from the reputed brand. Quality products, constant research and development for new and innovative features integration, timely delivery, best support and customer centric approach are some of the key features that have made Harsiddh Engineering a first line supplier in the local and global industry.

 

Ampoule filling is a delicate process that can be efficiently handled by specialized pharmaceutical ampoule filling equipment. Designed to keep the filling process fully automated, ampoule filling machines maintain consistency by offering options such as weight checking of product and laser sealing of filled ampoules.

 

Ampoule filling machines are designed to avoid direct contact with the drug, ensuring formulation efficacy is delivered to the target consumer. These machines cater to the varied requirements of pharmaceutical injectable industry like washing, sterilizing and filling & sealing line. The use of filling machines are considered important in the aspect of cleanliness, cost effectiveness, efficiency and accuracy.

 

You can be assured of the cleanliness in the preparation of the medicine with filling machines, as it is less possible for this machine to catch and transfer germs than when the human hands are used. These machines also guarantee efficiency and accuracy in the product since it is capable of doing the correct measurement of each component of a medicine. Pharmaceutical machinery manufacturers have different types of ampoule filling and sealing machine to offer such as packaging and sealing has different types. These seals are used for filling and sealing machine for ampoules, with a flexible, heat-seal coating material.

 

For More Information About Fille Machine Visit - www.harsiddhengineering.com/liquid-filling-machines/vial-...

 

Fresh meats hang on hooks outside a butcher shop. This is incredibly common, but I'm certain the USFDA would winch a bit if they saw this.

Glowing Skin is everyone's dream. Problems like Acne, Pimples, Dark Circles, Psoriasis and Skin Allergies can be treated with right Nutrition, Diet and Ayurveda

  

Acne & Pimples/PCOS Polycystic Ovarian Diseases:

Acne & Pimples

Acne Vulgaris can appear tender, red bumps, small white nodules, black heads deep & painful pus-filled cysts that can lead to scarring.

Face, Back, Chest shoulders are main spots.

Sufferers can experience embarrassment, poor self-esteem, anxiety and depression.

Suffering from a severe skin condition often leads social embarrassment, phobias, missed employment opportunities, and if not treated well may lead to suicidal tendencies.

In a journal of pediatrics and child health in New Zealand a study conducted on 10000 high school children, showed a strong link between severe skin condition and depression & suicidal tendencies. One in 3 Children with severe acne had suicidal thoughts and 1 in 10 had even tried to kill himself.

Many people turn to drug therapy but medications can not only be ineffective but also a potential health hazard with all sorts of side effects such as depression.

The acutane (isotretinoin generic) is often prescribed for chronic acne however the USFDA ranks it as one of the top ten drugs that can cause depression & lead to suicide attempts.

Antibiotics are generally not effective as the problem is more of a hormonal kind and not the infection, and infection happens only when it’s scratched with dirty hands. It may also lead to antibiotic resistance.

visit now:-https://www.tickmyhealth.com/skin-zone

  

Ashu Skin Care - Best Laser Hair Removal Skin Clinic in Bhubaneswar Odisha.

Unwanted hair is a troublesome factor of young girls & women. it is more aggravated in ladies suffering from PCOD. Ashu Skin Care has the latest FDA approved Diode laser machine for quick hair removal permanently. Here they offer permanent hair removal by both diode laser and IPL laser.

www.anitarath.Com

Ashu Skin care now considered to be the best dermatologist clinic for laser hair removal in Bhubaneswar, Odisha. The highlights of this top Laser Skin clinic are

1. Latest USFDA approved Diode Laser Machine

2. Absolutely Safe

3. Permanent hair removal

4. Less number of sessions

www.ashuskincare.com

Glowing Skin is everyone's dream. Problems like Acne, Pimples, Dark Circles, Psoriasis and Skin Allergies can be treated with right Nutrition, Diet and Ayurveda

Acne & Pimples/PCOS Polycystic Ovarian Diseases:

Acne & Pimples

Acne Vulgaris can appear tender, red bumps, small white nodules, black heads deep & painful pus-filled cysts that can lead to scarring.

Face, Back, Chest shoulders are main spots.

Sufferers can experience embarrassment, poor self-esteem, anxiety and depression.

Suffering from a severe skin condition often leads social embarrassment, phobias, missed employment opportunities, and if not treated well may lead to suicidal tendencies.

In a journal of pediatrics and child health in New Zealand a study conducted on 10000 high school children, showed a strong link between severe skin condition and depression & suicidal tendencies. One in 3 Children with severe acne had suicidal thoughts and 1 in 10 had even tried to kill himself.

Many people turn to drug therapy but medications can not only be ineffective but also a potential health hazard with all sorts of side effects such as depression.

The acutane (isotretinoin generic) is often prescribed for chronic acne however the USFDA ranks it as one of the top ten drugs that can cause depression & lead to suicide attempts.

Antibiotics are generally not effective as the problem is more of a hormonal kind and not the infection, and infection happens only when it’s scratched with dirty hands. It may also lead to antibiotic resistance.

  

Breast augmentation is one of the most popular breast procedures. This procedure increases the size of the breast using with autologous fat or USFDA approved implants. For further information regarding breast augmentation, please visit our website at www.drkashyap.com or write to us at info@drkashyap.com

 

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Advance Clinic is giving the best answer for hair fall treatment in delhi, body forming and against maturing. We offer deductively demonstrated treatment utilizing USFDA affirmed innovation. We are utilizing all items experienced broad research and trails in USA, Canada and India and treatment are at standard with exclusive expectation of value. goo.gl/OAMKLg

"Raptim Research Private Limited, is a global independent and internationally accredited Contract Research Organization (CRO). They provide comprehensive end-to-end clinical development and laboratory services with a full suite of integrated solutions, method validation and other analytical services to the pharmaceutical and biotechnology industries.

 

Their services include BA/BE Studies, In-Vitro Release Test (IVRT) and In-Vitro Permeation Test (IVPT) studies, Clinical Trials and much more. They are one of the best/top/leading contract research organization in India.

 

1. BA/BE Studies -

 

Raptim has conducted more than 1600+ BA BE studies in India and has about 35,000+ healthy volunteer data base.

 

Their Special Studies include:

- In Vivo Tape Stripping

- Glucose Clamp Studies

- Vivo Dermal Microdialysis

- Skin Blanching Studies

- Skin Irritation and Sensitization Test

- Veterinary BA/BE Studies

 

2. In-Vitro Release Test (IVRT) and In-Vitro Permeation Test (IVPT) studies -

Raptim Research, a leader in In-Vitro Release Test (IVRT) and In-Vitro Permeation Test (IVPT) studies, analytical method development, provides complete topical product development services utilizing in-vitro/in vivo penetration models and other scientific tools.

They offer validation and testing services that continue to meet the fast-growing demand for these types of topical and transdermal drug analytical services with the most up to date regulatory requirements.

 

3. Clinical Trials -

Raptim Research Private Limited provides a comprehensive range of services in focused therapeutic areas like Oncology, Respiratory, Psychiatry, Gynecology, Dermatology, Orthopedic, Nephrology, Neurology, Ophthalmology, Cardiology, Gastroenterology, Infection, Endocrinology, etc.

Their Clinical trial support team consists of highly experienced and qualified professionals. They have a combined industry expertise of more than 100 years. They have access to >1200 GCP-trained investigators with experience of handling inspection by major regulatory agencies like USFDA and EMA. www.raptimresearch.com/

 

Contact: www.raptimresearch.com/contact-us/

Email: contact@raptimresearch.com"

ANTISEPTIC HAND SANITIZER GEL | 70% Isopropyl Alcohol

(250 mL- 8.45 fl oz – Pump Bottle for Easy Application)

Active Ingredient:

Isopropyl Alcohol 70% v/v

Registered with USFDA ( NDC 79393-101-03) Keep hands safe and clean with Antiseptic topical gel throughout the day. Advanced Formula- Formulated at CDC recommended level, 70% Isopropyl Alcohol to kill 99.99% germs.

Soap-free, No-Rinse, towel-free antiseptic cleaning.

Quick-drying without needing towel or wipes.

Recommended for Repeated Use. No added Color or Fragrance. Designed with added glycerin to leave hands soft and smooth without drying.

Also available at packs of 4, 6, 8, and 12.

 

zhtherapeutics.com/product/250-ml-zh-antiseptic-hand-sani...

 

Phone : (561)-413-2135

E-mail : info@zhtherapeutics.com

smalik@zhtherapeutics.com

Address : 11437 Mantova Bay Circle Boynton Beach FL 33473, USA.

"Raptim Research Private Limited, is a global independent and internationally accredited Contract Research Organization (CRO). They provide comprehensive end-to-end clinical development and laboratory services with a full suite of integrated solutions, method validation and other analytical services to the pharmaceutical and biotechnology industries.

 

Their services include BA/BE Studies, In-Vitro Release Test (IVRT) and In-Vitro Permeation Test (IVPT) studies, Clinical Trials and much more. They are one of the best/top/leading contract research organization in India.

 

1. BA/BE Studies -

 

Raptim has conducted more than 1600+ BA BE studies in India and has about 35,000+ healthy volunteer data base.

 

Their Special Studies include:

- In Vivo Tape Stripping

- Glucose Clamp Studies

- Vivo Dermal Microdialysis

- Skin Blanching Studies

- Skin Irritation and Sensitization Test

- Veterinary BA/BE Studies

 

2. In-Vitro Release Test (IVRT) and In-Vitro Permeation Test (IVPT) studies -

Raptim Research, a leader in In-Vitro Release Test (IVRT) and In-Vitro Permeation Test (IVPT) studies, analytical method development, provides complete topical product development services utilizing in-vitro/in vivo penetration models and other scientific tools.

They offer validation and testing services that continue to meet the fast-growing demand for these types of topical and transdermal drug analytical services with the most up to date regulatory requirements.

 

3. Clinical Trials -

Raptim Research Private Limited provides a comprehensive range of services in focused therapeutic areas like Oncology, Respiratory, Psychiatry, Gynecology, Dermatology, Orthopedic, Nephrology, Neurology, Ophthalmology, Cardiology, Gastroenterology, Infection, Endocrinology, etc.

Their Clinical trial support team consists of highly experienced and qualified professionals. They have a combined industry expertise of more than 100 years. They have access to >1200 GCP-trained investigators with experience of handling inspection by major regulatory agencies like USFDA and EMA. www.raptimresearch.com/services/overview/

 

Contact: www.raptimresearch.com/contact-us/

Email: contact@raptimresearch.com"

Ashu Skin Care - Best Laser Hair Removal Skin Clinic in Bhubaneswar Odisha.

Unwanted hair is a troublesome factor of young girls & women. it is more aggravated in ladies suffering from PCOD. Ashu Skin Care has the latest FDA approved Diode laser machine for quick hair removal permanently. Here they offer permanent hair removal by both diode laser and IPL laser.

www.anitarath.Com

Ashu Skin care now considered to be the best dermatologist clinic for laser hair removal in Bhubaneswar, Odisha. The highlights of this top Laser Skin clinic are

1. Latest USFDA approved Diode Laser Machine

2. Absolutely Safe

3. Permanent hair removal

4. Less number of sessions

www.ashuskincare.com

Umedra Exports Pvt. Ltd. is one of the premier manufacturers and suppliers of healthcare products and medical disposables. The company is also a solution provider for private label and contract manufacturing.

We have come from a long way since we originated in 1995 in New Delhi, India. We began with production with few products. But, today we produce more than 400 products to support lifestyle and health of the people.

The organization mainly deals with personal care products for oral care, baby care, skincare, and hair care. We also provide a complete range of Ayurvedic products, OTC creams and medical disposables. These products are prepared by the finest people. Our employees, who we call experts, are the backbone of the success. We believe in treating them with respect and dignity.

The core competitive advantages that span us are well-equipped & cGMP compliant manufacturing and quality-control systems, superior regulatory expertise, in-depth market knowledge, extensive technical-customer support and strong R&D capabilities.

The USFDA registered company helps clients to succeed by delivering stable, effective, marketable products. We are known for our ability to accomplish the large size orders and customized demands of clients across the globe. Some of the major countries, we ship our products are USA, Haiti, Panama, Venezuela, Australia, Peru, Argentina, Singapore, Jamaica, Tanzania, Afghanistan, and many more.

The vision-driven organization discovers and upgrades processing system to deliver the best products and services to clients throughout the world.

For more information visit us at: www.umendra.com/otc-ointments-cream/creams

www.umendra.com/

ANTISEPTIC HAND SANITIZER GEL | 70% Isopropyl Alcohol

 

(1L – 33.8 fl oz – Pump Bottle for Easy Application)

 

Active Ingredient:

 

Isopropyl Alcohol 70% v/v

  

Registered with USFDA ( NDC 79393-101-05) Keep hands safe and clean with Antiseptic topical gel throughout the day. Advanced Formula- Formulated at CDC recommended level, 70% Isopropyl Alcohol to kill 99.99% germs.

 

Soap-free, No-Rinse, towel-free antiseptic cleaning.

 

Quick-drying without needing towel or wipes.

 

Recommended for Repeated Use. No added Color or Fragrance. Designed with added glycerin to leave hands soft and smooth without drying.

 

Also available at packs of 4, 6, 8, and 12.

  

zhtherapeutics.com/product/1l-zh-antiseptic-hand-sanitize...

 

zhtherapeuticssanitizer.blogspot.com/2021/07/zhtherapeuti...

  

Phone : (561)-413-2135

 

(971) 351-7528

 

E-mail : info@zhtherapeutics.com

 

smalik@zhtherapeutics.com

 

Address : 11437 Mantova Bay Circle Boynton Beach FL 33473, USA.

 

"Cargo Dry Pak" is a Container desiccant to keep your container moisture-free. Reduce moisture load on your export shipment by using USFDA approved Container Desiccant “ Cargo Dry Pak ”. Our Cargo Dry Pak is a specially formulated desiccant designed to,

- Eliminate condensation inside the shipping and storage container

- Absorb humidity, and control “dew point” temperature

- Protects the cargo from mold, mildew, rust, and corrosion while goods are in transit

Features of Cargo Dry Pak:

- Comes in Tyvek Paper spunbonded olefin, Type 1059B

- Adsorption capacity - more than 100 % of its own weight.

- Moisture protection - 60 Days

- Environment-friendly, Non-Toxic can be disposed of as normal waste. (ROHS Certified)

- Ship goods without the threat of container rain.