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Spoonful 6 is here!!!
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Fill Christmas Stockings, New Year's Resolutions and the post Xmas slumps with golden pages and soulful words...
Authors: Gülşen Uz, Tuğba Pesen, Ahsen Berber, Cenk Kığ, Bedia Palabıyık, Ayşegül Topal Sarıkaya
Abstract: Magnesium is vital for many biological processes such as energy metabolism, nucleic acid, and protein synthesis, signal transduction, and cell division. Impairment of magnesium homeostasis is associated with many diseases, especially cardiovascular diseases, hypertension, type 2 diabetes, and cancer. More than 300 million people worldwide struggle with type 2 diabetes, and this number is growing exponentially. Clinical studies have shown that serum magnesium levels were decreased in patients with type 2 diabetes and that magnesium supplementation has positive effects on glucose metabolism. In this study, glucose consumption and the expression levels of glucose transporters (ght1, ght2, ght5) were investigated in magnesium transportrestricted mutant strain of Schizosaccharomyces pombe yeast, which is similar to mammalian cells in terms of biological processes and genetic mechanisms. In mutant strain with limited magnesium transport, glucose consumption increased due to the increase in magnesium added to the medium. The expression level of ght1, ght2, one of the glucose transporters, increased in 30 mM Mg2+ supplemented medium, decreased at higher magnesium concentration (75 mM), where optimum growth was observed for the strain, and there was no significant change in the expression level of ght5. Our findings indicate that the glucose transporters ght1 and ght2 are regulated by a different mechanism than ght5.
Keywords: magnesium deficiency, glucose transport, S. pombe
Spoonful 6 is here!!!
We believe in a renaissance of WONDER!
Fill Christmas Stockings, New Year's Resolutions and the post Xmas slumps with golden pages and soulful words...
FREE GORGEOUS 'Kareena Zereofos' Hummingbird print with our FIRST 15 Subscribers & 5 Spoonful 6 Buyers! HOORAY & HAPPY HOLIDAYS EVERYONE!!!
Authors: Elifcan Caliskan, Berat Z. Haznedaroglu
Abstract: Chlorococcum novae-angliae is a terrestrial green microalgae species with remarkable potential to synthesize omega-3 (ω-3) and omega-6 (ω-6) fatty acids. In this study, Chlorococcum novaeangliae has been subjected to varying growth conditions (light, nitrogen, salinity, and temperature) to investigate the accumulation of ω-3 and ω-6 fatty acids. Among tested growth conditions, eicosapentaenoic acid, α-linoleic acid, γ-linoleic acid, and arachidonic acid were enhanced by nitrogen limitation. Significant increases were observed in concentration of linoleic acid, an essential precursor molecule for the production ω-6 fatty acids under decreased nitrogen concentrations. Despite the lowest biomass growth, monounsaturated fatty acids and docosahexaenoic acid were increased by 14.4% and 8.7% under low light intensities, respectively. Meanwhile, the highest concentrations of palmitic acid (C16:0), stearic acid (C18:0), and oleic acid (18:1cis-9) were also detected under nitrogen limitation. Total accumulation of ω-3 fatty acids was highest in the control group, followed by nitrogen limitation, whereas total ω-6 fatty acid accumulation was highest under nitrogen limitation followed by the control group. Total lowest fatty acid concentrations were obtained under increased salinity while low temperature conditions heavily inhibited cellular growth.
Keywords: Chlorococcum novae-angliae, essential fatty acids, microalgal lipids, omega fatty acids
Spoonful 6 is here!!!
We believe in a renaissance of WONDER!
Fill Christmas Stockings, New Year's Resolutions and the post Xmas slumps with golden pages and soulful words...
ift.tt/f8wXN17. 📣 It’s here! The January 2024 breakout issue of Speakers Magazine is now available, and it’s brimming with inspiration and empowerment. We’re thrilled to reveal our cover story featuring the phenomenal Dr. Willie Jolley, an award-winning speaker known for transforming lives with his dynamic message.
This issue is not just a read; it’s an experience! Alongside the captivating stories, you’ll find exclusive videos within the online issue, adding an extra dimension to your journey through these pages. Visit SpeakersMagazine.com now – read it, share it, devour it, and have a fabulous time diving into these motivational stories.
Joining Dr. Jolley are exceptional voices like Rodney C. Burris, Terrence Wilson, Pastor Andre Butler, Tiffany Bethea, LaJuanna Russell, Tyrese McAllister, Darlene Taylor
and Shannon Savoy. Each brings unique insights and powerful stories that are sure to ignite your passion and drive.
We’re beyond excited for you to discover the wealth of knowledge and inspiration in this issue. Let each page turn be a step towards your own greatness. Be inspired, get motivated, and remember – this is more than a magazine; it’s a movement!
🎉 Dive in, enjoy, and let’s make 2024 a year of remarkable achievements and stories worth telling. #SpeakersMagazine #Motivation #Inspiration #NewIssue #DrWillieJolly 🌟
[ift.tt/TG5cbIp] ift.tt/f8wXN17. 📣 It’s here! The January 2024 breakout issue of Speakers Magazine is now available, and it’s brimming with inspiration and empowerment. We’re thrilled to reveal our cover story featuring the phenomenal Dr. Willie Jolley, an award-winning speaker known for transforming lives with his dynamic message.
This issue is not just a read; it’s an experience! Alongside the captivating stories, you’ll find exclusive videos within the online issue, adding an extra dimension to your journey through these pages. Visit SpeakersMagazine.com now – read it, share it, devour it, and have a fabulous time diving into these motivational stories.
Joining Dr. Jolley are exceptional voices like Rodney C. Burris, Terrence Wilson, Pastor Andre Butler, Tiffany Bethea, LaJuanna Russell, Tyrese McAllister, Darlene Taylor
and Shannon Savoy. Each brings unique insights and powerful stories that are sure to ignite your passion and drive.
We’re beyond excited for you to discover the wealth of knowledge and inspiration in this issue. Let each page turn be a step towards your own greatness. Be inspired, get motivated, and remember – this is more than a magazine; it’s a movement!
🎉 Dive in, enjoy, and let’s make 2024 a year of remarkable achievements and stories worth telling. #SpeakersMagazine #Motivation #Inspiration #NewIssue #DrWillieJolly 🌟
Authors: Ozlem Bakir, Esabi Basaran Kurbanoglu
Abstract: In this study, water and methanol extracts were obtained from sea buckthorn seeds, which have an important place in health. It was aimed to determine the DPPH, ABTS antioxidant activities and urease, collagenase enzyme inhibition activities of these extracts. The inhibitory effect of the prepared extracts on these enzymes was evaluated by in vitro method. The best DPPH and ABTS scavenging activity was observed in aqueous extracts. DPPH (IC50 = 19.34±0.49 µg/mL) and ABTS (IC50 = 7.24±0.14 µg/mL) were determined. According to DPPH results, while aqueous extract provided 25,85 % removal, the methanolic extract provided 20,44 % removal. In ABTS removal activity, while aqueous extract provided 25,55 % removal, the methanolic extract provided 18,23% removal. The lower the IC50 value, the higher the free radical scavenging power. The best urease and collagenase inhibition from sea buckthorn seed extracts was seen in the aqueous extract (IC50 = 0,23 ± 0,003μg/mL, IC50 = 2,19 ± 1,12μg/mL). Methanol extracts did not show tyrosinase and urease enzyme inhibition. This study clearly shows that sea buckthorn the aqueous extract of can be used as an alternative source of anti-urease and anti-collagenase source. Due to the important role of these enzymes in various diseases, new drugs with inducing or inhibitory effects should be developed.
Keywords: Anti-urease activity, anti-collagenase activity,
enzyme inhibition, IC50, sea buckthorn seed
Authors: Abdullahi Ajao, Ganiyat Alasinrin
Abstract: This study investigated the spoilage patterns and biopreservation of tomato paste by lactic acid bacteria isolated from fermented milk products. All the isolates were screened for hydrogen peroxide, diacetyl, and lactic acid production. Isolate with the highest mean values of evaluating parameters was selected as protective culture for the biopreservation. The isolate was identified as Lactococus lactis strain Ganee-5 using molecular techniques, and the sequences were submitted to the Genbank Database to obtain the accession number (MH571417). Antimicrobial properties of the protective culture were evaluated against some selected spoilage bacteria E. coli (ATCC 25922), Listeria monocytogenes (ATCC 15313), Salmonella typhimurium (IFO 12529), and Staphylococcus aureus (ATCC 12600), varying zone of inhibitions ranged from 18-25 mm were detected. The potato paste was preserved with L. lactis culture, sodium benzoate and control samples while the control samples were left without preservatives. All the experimental set-up was left for 16 days. Physicochemical and nutritional analysis showed that tomato paste with L. lactis was preserved closely as much as sodium benzoate (p< 0.005). Therefore, L. lactis can be adopted for the preservation of the tomato paste to replace chemical preservatives.
Keywords: Protective culture, nutritional values, tomato paste, chemical preservatives, lactic acid, spoilage bacteria
The 12th issue (1th Issue in 2022, April) of the International Journal of Life Sciences and Biotechnology was published. "International Journal of Life Sciences and Biotechnology" is an international double peer-reviewed open access academic journal published on the basis of research- development and code of practice.
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“International Journal of Life Sciences and Biotechnology” dergisinin 12. sayısı (2022 yılı 1. sayısı, Nisan) yayınlandı. “International Journal of Life Sciences and Biotechnology” dergisi araştırma-geliştirme ve uygulama ilkeleri baz alınarak yayınlanan uluslararası hakemli açık erişimli akademik bir elektronik dergidir.
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