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Qiao's Pathology: Serous Papillary Cystadenofibroma of the Fallopian Tube by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing fibrotic cystic wall with focal calcifications and intraluminal papillary excrescences. H & E stain. 4X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Hyperplastic polyp of stomach by Qiao's Pathology (Art and Science in Medicine)

Gastric Polyp. Microscopic photo: Gastric polyp with elongated, tortuous or dilated gastric foveola, pyloric or fundic glands. H & E Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Hemangioblastoma of the Cerebellum by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing tumor tissue composed of proliferation of closely packed, thin walled, variable sized capillaries. The uninvolved cerebeller cortex is noted in the upper portion of the photo (blue arrows). H&E stain. 10x objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Qiao's Pathology: Molecular Subtype of Breast Carcinoma: Basal-like by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing a high grade invasive breast carcinoma. The tumor cells are negative for ER (estrogen receptor), PR (progesterone receptor), HER2/neu, and CK 5/6 (cytokeratin 5/6). However, the tumor cells are strongly positive for EGFR (epidermal growth factor receptor) (see insert). Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Schwannoma of the Nasal Cavity by Qiao's Pathology (Art and Science in Medicine)

Gross photo. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Lung Cancer Cells. - Cytology by Qiao's Pathology (Art and Science in Medicine)

Smears of needle biopsy with Papanicolaou's stain (or Pap stain). Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA. Microscopic photo 100X with oil.

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Qiao's Pathology: Atypical Lobular Hyperplasia (ALH) by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing tumor cells are negative for β-catenin, with no cell membrane stain. IHC stain. 40x. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Digital Papillary Carcinoma by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing a multilobular tumor with solid and papillary or micropapillary projections into the cystic areas. 4X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Usual Ductal Hyperplasia with Marked Myoepithelial Hyperplasia by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing a terminal duct filled with marked cellular proliferation. Irregular intraluminal fenestrations are present. Vacuolated myoepithelial cells and collagen fibers are also present in the intraluminal space. H & E Stain 10X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Giant Leiomyoma of the Uterine Fundus by Qiao's Pathology (Art and Science in Medicine)

Gross photo showing a longitudinally bivalved uterus with a giant leiomyoma in the uterine fundus. The cut surface of the leiomyoma is gray-white with whorled appearance and the mass is sharply circumscribed. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Two-Vessel Umbilical Cord by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing a cross section of an umbilical cord in which there is only a single artery and a vein: a "two vessel" umbilical cord. Such cords occur in about 1% of births. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Multiloculated, Non-invasive Mucinous Adenocarcinoma of Ovary by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing multiloculated complex cysts lined by atypical mucinous lining epithelium with nuclear stratification and goblet cells. Intracystic tumor necrosis is focally seen (black arrow). H & E stain. 20X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA. (乔建华医学博士， 美国病理学家学院专家会员。美国加州洛杉矶)

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Qiao's Pathology: Papillary Thyroid Carcinoma, Cytology Features by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing tumor cells from a fine needle aspiration cytology smear. Tumor cells exhibit nuclear features of papillary thyroid carcinoma, including indentation of nuclear envelope, deep nuclear groove, ground-glass (optically cleared or “Orphan Annie eye”) appearance of chromatin, and intranuclear cytoplasmic pseudoinclusions. Papanicolaou's stain. 100X Oil. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Molecular Subtype of Breast Carcinoma: HER2-enriched (HER2E) by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing a high grade invasive breast carcinoma. The tumor cells are negative for ER (estrogen receptor)(see insert), and negative for PR (progesterone receptor)(see insert). HER2/neu is overexpressed, and Ki-67 (proliferation rate) is high. This subtype tends to respond to drugs that target the HER2 protein. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Reactive Lymphoid Hyperplasia by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo. H & E stain. 10X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Mucosal Pseudolipomatosis of the Colon by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing benign colonic mucosa with numerous unlined variable sized clear spaces in the lamina propria. H&E stain. 20X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Qiao's Pathology: Lipomatosis of the Ileocecal Valve by Qiao's Pathology (Art and Science in Medicine)

Gross photo showing prominent and thickened ileocecal valve (Blue arrows). The cut surface is indicated by red arrows. T is terminal ileum mucosa. C is cecal mucosa.

Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Ovarian High-Grade Serous Carcinoma by Qiao's Pathology (Art and Science in Medicine)

Gross photo showing a large ovarian tumor with solid and cystic cut surface. Hemorrhage and necrosis are grossly visible. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Qiao's Pathology: Testicular Germ Cell Tumor - Seminoma by Qiao's Pathology (Art and Science in Medicine)

Gross Photo of a Radical Orchiectomy Specimen Showing: A large testicular tumor with bulky, homogeneous pink-tan lobulated and bulging cut surface. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Ovarian Fibroma by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing tumor cells are diffusely positive for WT-1. IHC stain. 20X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Eosinophilic Esophagitis by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing benign esophageal squamous mucosa with numerous intraepithelial eosinophils. H & E stain. 40X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Papillary Adenoma of the Gallbladder/Intracystic Papillary Neoplasm (ICPN) of the Gallbladder by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing neoplastic adenomatous tubules with areas of intestinal metaplasia. Foci of intraluminal acute inflammation are present. H & E stain. 10X Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Hibernoma of the Hand by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing an encapsulated tumor composed of lobulated and organoid arrangement of brown fat cells. H&E stain. 2X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Qiao's Pathology: Cholesterol gallstones by Qiao's Pathology (Art and Science in Medicine)

Gallbladder: Gross Photo. Cholesterol stones, numerous, yellow, round, and variable sized. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Qiao's Pathology: Xanthomatous Polyp of the Colon by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing benign polypoid colon mucosa with mild chronic inflammation and clusters of foamy histiocytes in lamina propria. H & E stain. 10X Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Adenocarcinoma in-situ, uterine cervix by Qiao's Pathology (Art and Science in Medicine)

Microscopic Photo. Adenocarcinoma in-situ. Notice the malignant nuclear features lining epithelium, including hyperchromasia, enlarged and elongated nuclei, and a few mitotic figures and apoptotic bodies. H&E Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Ovarian Dermoid Cyst (Mature Cystic Teratoma) by Qiao's Pathology (Art and Science in Medicine)

Gross photo of an opened ovarian cyst with hairs and greasy sebaceous material. A tooth is indicated by a red arrow. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Malignant Pleural Effusion with Metastatic Breast Cancer Cells, Cytology by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing a few clusters of malignant tumor cells forming glands/ducts. Reactive mesothelial cells and a few small mature lymphocytes are present in the background. Cell block section. H & E stain. 100 X oil. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Tubular Adenoma of Duodenum (乔氏病理学：十二指肠管形腺瘤) by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing a duodenal polyp with proliferation of neoplastic tubules. The neoplastic tubules are hyperchromatic with diminished cytoplasmic mucin production. The normal duonenal villi are present at the left side of the photo. H & E stain. 20X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA. (乔建华医学博士， 美国病理学家学院专家会员。美国加州洛杉矶)

 

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Qiao's Pathology: Pigment gallstones by Qiao's Pathology (Art and Science in Medicine)

Gallbladder: Gross Photo. Pigment stones, numerous, brown, irregular, and variable sized. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Qiao's Pathology: Mucinous Carcinoma of the Gallbladder by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing abundant extracellular mucin pools and a few tumor cell clusters H & E stain. 10X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Acute Pulmonary Histoplasmosis by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo. H & E and GMS fungal stains. 40X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Chronic Hepatitis C by Qiao's Pathology (Art and Science in Medicine)

Microscopic Photo. Chronic hepatitis C. Trichrome stain demonstrates bridging fibrosis with architectural distortion and cirrhosis (stage 4). Trichrome Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: NK/T-cell Lymphoma, Nasal Type by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing large tumor cells, apoptotic tumor cells, lymphoglandular bodies (red arrows), and small lymphocytes. Intraoperative touch prep smear. H & E stain. 100X oil objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Platelet Satellitism by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing blood smear made from EDTA anticoagulated blood showed many polymorphonuclear leucocytes to be surrounded by platelet in a rosette-like fashion. Wright-Giemsa Stain. 100X oil magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Benign Phyllodes Tumor of Breast by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo. The tumor shows stromal hypercellularity, particularly next to epithelial elements. H&E Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Acute funisitis. by Qiao's Pathology (Art and Science in Medicine)

Umbilical Cord. Microscopic photo: Section shows neutrophilic infiltration of an umbilical artery. H & E Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Xanthogranulomatous Cholecystitis by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo shows markedly thickened gallbladder wall with chronic cholecystitis and nodular aggregation of histiocytes. H & E stain. 2X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Diabetic Peripheral Artery Disease by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing cross section of posterior tibial artery with circumferential medial calcifications, foci of ossification and 75 % of luminal stenosis. H & E stain. 10X Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Mucocele of Appendix by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing a cross section of a dilated appendix filled with tenacious mucinous secretion. Mucin focally dissects into the appendix wall. H & E stain. 4X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Papillary Thyroid Carcinoma, Cytology Features by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing tumor cells from a fine needle aspiration cytology smear. Tumor cells exhibit nuclear features of papillary thyroid carcinoma, including indentation of nuclear envelope, deep nuclear groove, ground-glass (optically cleared or “Orphan Annie eye”) appearance of chromatin, and intranuclear cytoplasmic pseudoinclusions. Papanicolaou's stain. 100X Oil. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Bladder Calculi by Qiao's Pathology (Art and Science in Medicine)

Gross photo of four yellow tan irregular bladder stones. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Cholesterol gallstones by Qiao's Pathology (Art and Science in Medicine)

Gallbladder: Gross Photo. Cholesterol stones, multiple, yellow, irregular, and variable sized. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Ovarian Fibroma by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing tumor cells are diffusely positive for PR (Progesterone Receptor). IHC stain. 20X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Kidney - Cytomegalovirus (CMV) Infection by Qiao's Pathology (Art and Science in Medicine)

Microscopic Photo. Five enlarged renal tubular epithelial cells with enlarged basophilic nuclei with inclusions. Tubular injury is present. H&E Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Colon - Tubulovillous Adenoma by Qiao's Pathology (Art and Science in Medicine)

Microscopic Photo. A tubular adenoma with proliferation of neoplastic tubules. The neoplastic glands are lined by hyperchromatic glandular epithelium with elongated nuclei and reduced cytoplasmic mucin production. Surface villous architecture formation is noted. H&E Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Platelet Satellitism by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing blood smear made from EDTA anticoagulated blood showed many polymorphonuclear leucocytes to be surrounded by platelet in a rosette-like fashion. Wright-Giemsa Stain. 100X oil magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Colon - Tubular Adenoma with High Grade Dysplasia by Qiao's Pathology (Art and Science in Medicine)

Microscopic Photo. Tubular adenoma with focal high grade dysplasia. The high grade dysplasia shows complex glands and focal intraluminal tumor necrosis. There is no mucosal stromal desmoplastic reaction. H&E Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Qiao's Pathology: Ovarian Fibroma by Qiao's Pathology (Art and Science in Medicine)

Microscopic photo showing tumor cells are diffusely positive for inhibin A. IHC stain. 20X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Qiao's Pathology: Colon - Tubular Adenoma by Qiao's Pathology (Art and Science in Medicine)

Microscopic Photo. The neoplastic glands are lined by hyperchromatic glandular epithelium with elongated nuclei and reduced cytoplasmic mucin production. The normal crypts are at right lower corner. H&E Stain. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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