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Microscopic photo showing cystic wall lined by mature stratified squamous epithelium with hyperkeratosis. Keratin debris and a hair shaft are present in the cystic contents. H & E stain. 10X Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing scattered spindle cells with rounded to oval shaped nuclei and moderate amounts of pale cytoplasm. Hyperchromatic atypical cells are also present and suspicious for malignancy. Pap stain. Original magnification 40X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Gross photo showing a bivalved kidney with a large tumor at the upper pole (dotted highlight rectangle). A large scar is present in the center of the tumor. The tumor is light brown in color. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Gross photo showing a segment of resected sigmoid colon with a large perforation ( green P and arrows). The disrupted colon wall is grossly hemorrhagic. The gut was perforated by an expanded jacketed hollow-point bullet which looks like a fully opened flower. The term hollow-cavity bullet is used to describe a hollow point where the hollow is unusually large, sometimes dominating the volume of the bullet, and causes extreme expansion or fragmentation on impact. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing calcifications (green arrows) in fibrous capsular tissue. H and E stain. Objective amplification 10x. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing tumor cells are positive for RCC, vimentin, AMACR, and CD10. IHC stain. 40X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing an infarcted intraductal papilloma with necrotic papillae and tumor cells. H&E stain. Original objective magnification 10X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Microscopic photo showing monotonous tumor cells in expended lobules and associated terminal duct. H & E stain. 10X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo a demyelinated plaque filled with sea of histiocytes. Perivascular lymphocytic proliferation with scattered plasma cells is identified in the demyelinated plaque. H & E stain. 10X Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing embryonal carcinoma and extensive tumor necrosis. H & E Stain 20X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing spindle cell lesion is diffusely positive for vimentin. IHC stain. Original magnification 20X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Microscopic photo showing nodular tumor tissue with areas of tumor necrosis. H & E stain. 2X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing two clusters of tumor glands/cells are in the lymphovascular spaces (yellow arrows). H & E stain. 40X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Microscopic photo showing dilated appendix lumen filled with abundant mucin in distal tip of the appendix. The appendiceal mucosa is atrophic and flattened. No neoplastic glandular epithelial cells are seen. H&E stain. Original magnification 4X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Microscopic photo showing extensive infiltration of neutrophils in a tubal plica. H & E stain. 40X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Microscopic photo showing hypercelluar stromal tissue with frequent mitotic figures. H&E stain. 40X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Microscopic photo showing spindle cells are negative for p63 in cell block section. IHC stain. Original magnification 40X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Microscopic photo showing spindle cells are negative for p40 in cell block section. IHC stain. Original magnification 20X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Microscopic photo showing an encapsulated tumor composed of lobulated and organoid arrangement of brown fat cells. H&E stain. 2X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Gross photo showing the entrance (blue arrow) of the small bowel interception. The telescoped or herniated small bowel entered here into the terminal ileum, cecum, and ascending colon. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing tumor tissue with clusters of mature adipocytes, bundles of spindle cell proliferation, and numerous variable sized thick-walled vessels. H & E stain. Original magnification: 20x. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Microscopic photo showing tumor tissue with clusters of mature adipocytes, bundles of spindle cell proliferation, and numerous variable sized thick-walled vessels. H & E stain. Original magnification: 10x. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Gross photo showing a large ulcerated tumor (white arrow) with green-black surface located at the splenic flexure. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing nests of metastatic tumor in vertebral bone with patchy tumor necrosis (black arrow). H & E stain. 20X Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Gross photo showing a bivalved kidney with a large tumor at the upper pole (dotted highlight rectangle). A large scar is present in the center of the tumor. The tumor is light brown in color. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing tumor cells are diffusely positive for CK-5/6. IHC stain. 20X objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

 

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Microscopic photo showing carotid atherosclerotic plaque, endarterectomy specimen, with scattered multinucleated giant cells. H & E stain, 40X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing a hydropic villi with circumferential proliferation of hyperplastic trophoblasts. Central cistern formation (internal clefting) is present. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing affected fallopian tube with thichened wall filled with numerous foamy histiocytes and lymphocytes. H&E stain. Original magnification 20X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA

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Microscopic photo showing one tumor cell (black arrow) with two eyes on both sides. Ingested red blood cells are vaguely seen in the cytoplasm between two eyes. Papanicolaou stain. 40x. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Gross photo showing the entrance (blue arrow) of the small bowel interception. The telescoped or herniated small bowel entered here into the terminal ileum, cecum, and ascending colon. (Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing dilated appendix filled with tenacious mucinous secretion. Mucin focally dissects into the appendix wall. Aggregations of psmmoma bodies are present in the mucn. H & E stain. 4X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing diffuse proliferation of solid sheets of invasive tumor cells with scatered signet ring cells in this gastric mucosal biopsy. The gastric mucosa also exhibits mild to moderte chronic gastritis. H & E stain. 10X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing tumor cells are positive for pankeratin (AE1/AE3). IHC stain. 40X. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Microscopic photo showing fibrous capsular tissue (between green arrows). H and E stain. Objective amplification 10x. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing highly pleomorphic giant cells. Scattered inflammatory cells and anthracotic pigments are present in the background of smear. Pap stain. 100X oil. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing an irregularly shaped aggregate of tumor cells with enlarged nuclei, opened chromatin, prominent nucleoli, and decreased cytoplasmic granularity. FNA Smear. Pap Stain. 100X oil. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Microscopic photo showing focal perineural invasion. H & E stain. Original objective magnification 20x. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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