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A method of mass-producing disease-fighting antibodies entirely within bacteria has been developed by a research group at The University of Texas at Austin. The group led by Dr. George Georgiou developed the new antibody-production approach to improve upon processes used previously to identify new drugs for arthritis, cancer and other diseases. The new approach developed in collaboration with Dr. Brent Iverson in the Department of Chemistry and Biochemistry is faster and has other advantages.
Above photo:
Postdoctoral student Yariv Mazor (on the right), lead author of the journal article, engineered antibodies to an anthrax toxin called PA. Graduate student Thomas Van Blarcom (on the left), then used a method called APEx, co-developed by Georgiou and Iverson’s lab, to identify the bacteria-bound antibodies that attached best to the PA. Van Blarcom then grew large numbers of those bacteria to begin refining the steps needed for mass-scale production of promising therapeutic antibodies.
Andy Gossett, Center for Manufacturing Excellence Technician, directs Connor Millwood and Taylor Campbell as they hold the pieces already cut by the water jet in place while the machine completes it's tasks. Photo by Robert Jordan/Ole Miss Communications
Erick Burke a contracted maintence worker uses a powersaw to cut trees and clear debris on the barge 'PRIDE of the Cumberland' on July 24, 2013. (USACE photo by Mark Rankin)
Dr. Christine Schmidt, a biomedical engineer at The University of Texas at Austin, developed a method for replacing damaged nerves that simplifies surgeries to repair damaged peripheral nerves, which carry signals for motion or touch between the brain and muscles-- and potentially reduces risks.
Curt Deister (left), a chemical engineering graduate student who began working under Schmidt’s guidance in 2001, made adjustments to the original detergent solution to process human nerve tissue obtained from tissue banks. Deister also modified the detergent processing steps for use with larger and more complex human nerves. Deister continued refining the human nerve preparation process after joining Axogen as a Product Development manager in 2007. This included combining the detergent approach with technology developed at the University of Florida, Gainesville, to further enhance regrowth of severed nerves.
Alydia Jura, an undergraduate in mechanical engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Alydia Jura, an undergraduate in mechanical engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Alydia Jura, an undergraduate in mechanical engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Center for Manufacturing Excellence Technician James McPhail gives some advice on setting up a router table to a team that is putting the finishing touches on their 'Cajon', a type of African bass drum, they are building as their capstone project. Photo by Robert Jordan/Ole Miss Communications
Alydia Jura, an undergraduate in mechanical engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Alydia Jura, an undergraduate in mechanical engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Alydia Jura, an undergraduate in mechanical engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Yuang Guo, a masters student in environmental engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Yuang Guo, a masters student in environmental engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Dr. Jose Yacaman, professor of chemical engineering, has been studying the biological potential of nanoparticles for decades. Among his students is Reeja Jayan. The doctoral student in electrical engineering poses with gold nanoparticles displayed on a computer screen.
Teammates Taylor Campbell, Connor Millwood and Andrew Gaddis test the fit of the bluetooth speaker cabinet pieces that were cut on the water jet. The team is one of several working in the CME shop to complete their capstone projects. Photo by Robert Jordan/Ole Miss Communications
Thursday 4 February engineering students from Georgia Tech on study program to New Zealand visited the US Embassy and met with Ambassador Huebner. The Ambassador answered questions about his role and the range of subjects covered by the US Embassy and New Zealand.
Yuang Guo, a masters student in environmental engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
Yuang Guo, a masters student in environmental engineering studying amidst the colors and quiet of the Courtyard between the Electrical and Engineering and Computer Science building and the George G. Brown Laboratories building on the North Campus of the University of Michigan in Ann Arbor on Wednesday afternoon, October 12, 2022.
Fall colors are taking over the campus as temperatures begin to drop.
Photo: Brenda Ahearn/University of Michigan, College of Engineering, Communications and Marketing
SOMERSET, Ky - A U.S. Army Corps of Engineers sign at the Waitsboro Recreation area displays key information to boaters. (USACE photo by Mark Rankin)
Like most other civil engineering students, Trevor Walker’s hectic schedule involves passing, playing and sometimes scrambling. His nimble mind and keen eye for detail prove handy for his college football career as well. In December 2009, the NCAA Big 12 Conference recognized his abilities in both the classroom and the field when they named him to its Academic All-Big 12 football team. A senior specializing in geotechnical engineering from Mt. Pleasant, Tex., Trevor qualified by maintaining a 3.20 or better grade point average and lettering in Longhorn football.
Among the engineering students who are part of the research team, led by Dr. Arumugam Manthiram, to produce methanol-powered fuel cells are: (from left to right): Kaushik Alayavalli, doctoral student in materials science and engineering; Tim Silverman, doctoral student in mechanical engineering; Wen Li, doctoral student in materials science and engineering; and Adam Stockett, doctoral student in chemistry and biochemisty.
Camp Bevo 2007
The University of Texas at Austin Department of Petroleum and Geosystems Engineering began the "intersession" program three years ago as a student retention tool. For many participants it represented their first introduction to an actual oilfield outside of university laboratories.
Thursday 4 February engineering students from Georgia Tech on study program to New Zealand visited the US Embassy and met with Ambassador Huebner. The Ambassador answered questions about his role and the range of subjects covered by the US Embassy and New Zealand.
Mechanical Engineering Ph.D. student Marcus Ashford has been named the 2004 Graduate Student of the Year by the National Society of Black Engineers (NSBE) for his groundbreaking automobile research.
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