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"A glimpse inside Angiostrongylus vasorum" by Andreas Oehm, University of Zurich

Entry in category 1 Object of study; Copyright CC-BY-NC-ND: Andreas Oehm

 

This image shows a cross-section of a female Angiostrongylus vasorum specimen, the "French heartworm," a parasitic nematode of dogs and other canids. Red fluorescence highlights the binding of a monoclonal antibody to a target protein, likely ribosomal protein S19e, in the parasite's intestinal lining, while blue DAPI stains mark the nuclei. Ribosomal protein S19e is thought to play a role in host-parasite interactions, potentially influencing immune modulation. Captured using immunofluorescence microscopy, the image reveals the parasite’s intricate molecular architecture. This research sheds light on A. vasorum, a parasite that causes severe cardiovascular and respiratory disease. By identifying key antigens, it paves the way for potential therapeutic targets, improving animal health. The vibrant contrast and structural detail highlight the morbid beauty of parasitic worms, transforming an unsettling subject into a visually compelling microscopic image.

 

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Uploaded on April 14, 2025