"Confocal microscopy picture from the cerebellum" by Edith Marianne Schneider Gasser, University of Zurich
Entry in category 3. Locations and instruments; © CC-BY-NC-ND: Edith Marianne Schneider Gasser
"The cerebellum interneurons orchestra" In this image of the developing mouse cerebellum, interneurons are labelled in red and green. It is possible to appreciate the perfect organization of the different cell types. They all build a specific conformation in which is easy to imagine that each cell plays a tone, and together they make the orchestra.
GAD enzymes are responsable for the production of GABA, a neurotransmitter exclusively expressed in interneurons in the brain. With the use of genetic engineering, a red fluorescent protein (tdTomato) was inserted to a enzyme isoform 65 (GAD 65) and a green fluorescent protein (GFP) was introduced to the other isoform 67 (GAD 67). In blue is possible to appreciate DAPI a marker of all cell nuclei in the brain. Image of a lobe in the cerebellum was taken in a confocal microscope at a 25X magnification.
"Confocal microscopy picture from the cerebellum" by Edith Marianne Schneider Gasser, University of Zurich
Entry in category 3. Locations and instruments; © CC-BY-NC-ND: Edith Marianne Schneider Gasser
"The cerebellum interneurons orchestra" In this image of the developing mouse cerebellum, interneurons are labelled in red and green. It is possible to appreciate the perfect organization of the different cell types. They all build a specific conformation in which is easy to imagine that each cell plays a tone, and together they make the orchestra.
GAD enzymes are responsable for the production of GABA, a neurotransmitter exclusively expressed in interneurons in the brain. With the use of genetic engineering, a red fluorescent protein (tdTomato) was inserted to a enzyme isoform 65 (GAD 65) and a green fluorescent protein (GFP) was introduced to the other isoform 67 (GAD 67). In blue is possible to appreciate DAPI a marker of all cell nuclei in the brain. Image of a lobe in the cerebellum was taken in a confocal microscope at a 25X magnification.