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Atypical carcinoid tumor of lung metastatic to the adrenal gland Case 255

Palisading of columnar cells at the periphery of tumor trabeculae.

The term atypical carcinoid may be somewhat misleading since it may give the impression of a low grade of malignancy when if fact these are fully malignant neoplasms in which distant metastases are present in about 20% of patients at presentation and the disease free survival after 10 years is about 50%. An alternate name - neuroendocrine carcinoma grade 2 - has been suggested. I believe that this is preferable to atypical carcinoid but others are unwilling to accept this terminology.

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Uploaded on December 12, 2012
Taken on May 16, 2012