Pathology Outlines
Solitary fibrous tumor
Contributed by: Dr. Bushra Sikandar, The Dow University of Health and Sciences (Pakistan).
60 year old man with circumscribed encapsulated solid lobulated mass over soft palate. Clinically, it resembled neurofibroma.
On H&E, a well circumscribed lesion comprising of interlacing bundles of elongated cells (arranged in forms of haphazard fascicles having wavy hyperchromatic nuclei with inconspicuous nucleoli) was examined. Interspersed stroma showed dense collagen bundles.
IHC:
CD34 and BCL2: positive
S-100 and ASMA: negative
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Solitary fibrous tumor
Contributed by: Dr. Bushra Sikandar, The Dow University of Health and Sciences (Pakistan).
60 year old man with circumscribed encapsulated solid lobulated mass over soft palate. Clinically, it resembled neurofibroma.
On H&E, a well circumscribed lesion comprising of interlacing bundles of elongated cells (arranged in forms of haphazard fascicles having wavy hyperchromatic nuclei with inconspicuous nucleoli) was examined. Interspersed stroma showed dense collagen bundles.
IHC:
CD34 and BCL2: positive
S-100 and ASMA: negative
Click here to see topic.