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DHHC enzymes

In this image: Molecular view of DHHC palmitoyltransferases. Human DHHC20 (yellow) is embedded in the Golgi membrane (green), a compartment located inside cells. DHHC20 attaches a fatty acid chain (white) to a target protein (blue, foreground), which anchors the protein to the Golgi membrane.

 

NIH researchers have reported the first 3D structure of DHHC enzymes, which are involved in many cellular processes, including cancer. The finding promises to improve drug design for common forms of cancer.

 

More information: www.nih.gov/news-events/news-releases/nih-researchers-rep...

 

Credit: Jeremy Swan, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH

 

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Uploaded on January 19, 2018