Muscles regenerated after prostaglandin E2 injection
This cross-section of regenerated muscle shows muscle stem cells (red) in their niche along the muscle fibers (green). The blue dots are DNA in the nuclei of the fibers. Researchers have found that injecting the molecule prostaglandin E2 into muscles after injury induces muscle stem cell division and accelerates regeneration. Prostaglandin E2 is an inflammatory molecule released in response to muscle injury or rigorous exercise.
Credit: Helen M. Blau, Ph.D., Andrew T.V. Ho, Ph.D., and Adelaida R. Palla, Ph.D., Stanford University School of Medicine.
NIH support from: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Muscles regenerated after prostaglandin E2 injection
This cross-section of regenerated muscle shows muscle stem cells (red) in their niche along the muscle fibers (green). The blue dots are DNA in the nuclei of the fibers. Researchers have found that injecting the molecule prostaglandin E2 into muscles after injury induces muscle stem cell division and accelerates regeneration. Prostaglandin E2 is an inflammatory molecule released in response to muscle injury or rigorous exercise.
Credit: Helen M. Blau, Ph.D., Andrew T.V. Ho, Ph.D., and Adelaida R. Palla, Ph.D., Stanford University School of Medicine.
NIH support from: National Institute of Arthritis and Musculoskeletal and Skin Diseases