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RNA Interference (RNAi) Technology

Scientists at the National Institutes of Health have used RNA interference (RNAi) technology to identify dozens of genes which may represent new therapeutic targets for treating Parkinson’s disease. The findings also may be relevant to several diseases caused by damage to mitochondria, the biological power plants found in cells throughout the body. NIH scientists used RNAi to find genes that interact with parkin (green), a protein that tags damaged mitochondria (red). Mutations in parkin are linked to Parkinson’s disease and other mitochondrial disorders.

 

Credit: National Center for Advancing Translational Sciences (NCATS), National Institutes of Health

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Uploaded on January 8, 2016