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Confusing left and right | Free educational graphics

Drawing of four torsos showing the position of lungs, heart, liver, stomach and spleen in normal bodies and ones with left-right abnormalities.

 

Sometimes an embryo gets its left-right signals crossed, and internal organs develop improperly. In the complete reversal known as situs inversus, organs like the stomach, heart, spleen and liver end up in mirror-image positions compared to the normal layout (known as situs solitus). And sometimes, the embryo ends up with two “right” or two “left” sides, a condition known as atrial isomerism, which can affect the structure of the heart, position of the liver, the number of spleens and the number of lobes in each lung, as well as other abnormalities. Whereas people can live perfectly healthily in cases of a complete reversal, the heart defects of atrial isomerism, particularly right atrial isomerism, can be severe.

 

 

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Read more in Knowable Magazine

 

How do bodies map out left and right?

FIVE BIG QUESTIONS: Early in development, an embryo must “break symmetry” to position organs and other parts correctly.

www.knowablemagazine.org/article/living-world/2020/how-do...

 

Read more from Annual Reviews

 

Fluid Dynamic Mechanism Responsible for Breaking the Left-Right Symmetry of the Human Body: The Nodal Flow, Annual Review of Fluid Mechanics

Fluid flow in the embryo’s left-right organizer, a temporary organ, creates the left-right distinction. Cilia beat to push the fluid leftward, potentially delivering membranous bubbles containing chemicals that mark one side as left.

 

 

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Knowable Magazine from Annual Reviews is a digital publication that seeks to make scientific knowledge accessible to all. Through compelling articles, beautiful graphics, engaging videos and more, Knowable Magazine explores the real-world impact of research through a journalistic lens. All content is rooted in deep reporting and undergoes a thorough fact-checking before publication.

 

The Knowable Magazine Science Graphics Library is an initiative to create freely available, accurate and engaging graphics for teachers and students. All graphics are curated from Knowable Magazine articles and are free for classroom use.

 

Knowable Magazine is an editorially independent initiative produced by Annual Reviews, a nonprofit publisher dedicated to synthesizing and integrating knowledge for the progress of science and the benefit of society.

 

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Uploaded on August 24, 2022
Taken on January 30, 2020