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A team led by engineers at UC San Diego has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals’ cortex and responded to external sensory stimuli. The implanted organoids reacted to visual stimuli in the same way as surrounding tissues, an observation that researchers were able to make in real time over several months thanks to an innovative experimental setup that combines transparent graphene microelectrode arrays and two-photon imaging.

 

Learn more: today.ucsd.edu/story/human-brain-organoids-implanted-into...

 

Pictured here: Madison Wilson, a PhD student at UC San Diego and first author of the study.

 

Photos by: David Baillot/ UC San Diego Jacobs School of Engineering

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Uploaded on January 6, 2023
Taken on December 7, 2022