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Qiao's Pathology: Adenocarcinoma of the Prostate with Perineural Invasion

Microscopic photo showing tumor glands growing along a nerve bundle (black arrow). Perineural invasion (PNI) is a major mechanism of prostate cancer extension from prostatic parenchyma to periprostatic soft tissue, PNI extensive enough to be sampled on needle biopsy may signal an increased likelihood of extraprostatic extension of cancer or, ultimately, of cancer recurrence. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

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Uploaded on October 20, 2012
Taken on October 20, 2012