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Qiao's Pathology: Chemotherapy Effects on Breast Cancer Cells

Microscopic photo showing clusters of residual tumor cells after neoadjuvant chemotherapy. The morphologic changes include distortion of glandular architecture, enlarged tumor cells due to increased cytoplasm, cytoplasmic vacuolization and eosinophilic change, pleomorphic and bizarre nuclei, and decreased mitotic activity. H&E stain. 40x original objective magnification. Jian-Hua Qiao, MD, FCAP, Los Angeles, CA, USA.

 

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Uploaded on September 15, 2016