The Chronic Toxicity Studies of Camellia Seed Oil Containing Tea Saponins on Mice Blood and Organs

The Chronic Toxicity Studies of Camellia Seed Oil Containing Tea Saponins on Mice Blood and Organs

 

Authors: Hadeel O. A. Ahmed , Abdalbasit A. Mariod ,Tarig A. A. Hammoda

 

Abstract: Tea saponins are normal non-ionic surfactants with surface-dynamic (surfactant) properties, isolated from the Camellia oleifera seed. These saponins are more prominent than 10% of the camellia seed and are used as a natural tenside that is thoughtful to the environment. Camellia seed oil containing tea saponins was used as the main material. Three experimental groups were used: Low, Medium, and High groups with different doses. 30 days feeding in mice experiment. Mice blood and organs were used to analyze the chronic toxicity among the experimental rats in 30 d and olive oil used as a control group. The study showed that, there were significant differences in some index and there were no vital changes in the other indicators. The analysis of the results indicates that, camellia oil containing tea saponins have some toxic effects in functions of viscera, peripheral blood in mice. The results provides a theoretical basis for the utilization and safety of camellia oil. The chronic toxicity of camellia oil containing tea saponin was not strong, feeding on mice in a high dose (255 mg/kg·bw low tea saponin/oil) for 30 days each viscera and other features and growth have no significant impacts.

 

Keywords: Camellia seed oil, tea saponins, mice, blood, organs, hemogram, histology

 

dergipark.org.tr/tr/download/article-file/1336007

 

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