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Mineralization of alveolar wall blood vessels - Chronic passive congestion

Old hemorrhage (hemosiderin-laden macrophages in airspaces), interstitial fibrosis and focal mineralization (deposition of iron and calcium) of vascular elastic fibers in alveolar walls secondary to hemorrhage. Mineralized foci that are not obviously blood vessels could represent mineralization of alveolar wall elastic fibers or could be tangential cuts of blood vessels without obvious lumens.

The patient, an infant with complex congenital heart disease, had chronic passive pulmonary congestion from prolonged heart failure.

Hemorrhage-associated mineralization in the lungs is often erroneously referred to as "endogenous pneumoconiosis" This term is a misnomer because it is definitely not a pneumoconiosis.

 

Image contributed by Dr. Michael Bayerl - @MGBayerl_MD

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Uploaded on April 17, 2023
Taken on April 20, 2023