CodonAUG
Neural stem cell
The GFP+ (green) neuron depicted is an embryonic radial glia stem cell.
These cells are found in an area called the ventricular zone during embryonic development and this area unsurprisingly flanks the ventricles of the brain.
These radial glia stem cells will give rise to neurons and glia.
Notice that there appears to be projections moving upwards (towards pial surface) and downwards (toward ventricle) from the soma of the stem cell. These are projections that are important to cellular migration of daughter cells and orienting the stem cell itself.
Image is a ~30 micron thick coronal section of the somatosensory cortex of an embryonic mouse brain.
Blue=DAPI (Binds DNA, marks nucleus)
Red = Pax6 (Transcription factor and marker of pluripotency)
Green = GFP (From jellyfish, used to identify affected cells in an experiment)
Neural stem cell
The GFP+ (green) neuron depicted is an embryonic radial glia stem cell.
These cells are found in an area called the ventricular zone during embryonic development and this area unsurprisingly flanks the ventricles of the brain.
These radial glia stem cells will give rise to neurons and glia.
Notice that there appears to be projections moving upwards (towards pial surface) and downwards (toward ventricle) from the soma of the stem cell. These are projections that are important to cellular migration of daughter cells and orienting the stem cell itself.
Image is a ~30 micron thick coronal section of the somatosensory cortex of an embryonic mouse brain.
Blue=DAPI (Binds DNA, marks nucleus)
Red = Pax6 (Transcription factor and marker of pluripotency)
Green = GFP (From jellyfish, used to identify affected cells in an experiment)