Berkeley Lab
Silence of the Genes
Electron microscopy structure of the human RISC-loading complex, with the L-shaped Dicer enzyme shown as a wire map and the Argonaute2 protein, shown in purple.
Berkeley researchers have solved the structure of a protein complex that helps determine the fate of human cells. Called a RISC-loading complex, this structure consists of small RNA molecules that control whether genetic messages are silenced or expressed.
Silence of the Genes
Electron microscopy structure of the human RISC-loading complex, with the L-shaped Dicer enzyme shown as a wire map and the Argonaute2 protein, shown in purple.
Berkeley researchers have solved the structure of a protein complex that helps determine the fate of human cells. Called a RISC-loading complex, this structure consists of small RNA molecules that control whether genetic messages are silenced or expressed.