Cell Model of Huntington's Disease
In a cell model of Huntington’s disease, the compound NCT-504 lowers the amount of toxic protein in the cell by inhibiting the enzyme PIP4Kγ. Here, the panels show cells before (top) and after treatment (bottom) with NCT-504. The right column indicates the abundance of the toxic protein. The cells after treatment with NCT-504 show a significant decrease in toxic protein accumulation.
Credit: National Center for Advancing Translational Sciences
Cell Model of Huntington's Disease
In a cell model of Huntington’s disease, the compound NCT-504 lowers the amount of toxic protein in the cell by inhibiting the enzyme PIP4Kγ. Here, the panels show cells before (top) and after treatment (bottom) with NCT-504. The right column indicates the abundance of the toxic protein. The cells after treatment with NCT-504 show a significant decrease in toxic protein accumulation.
Credit: National Center for Advancing Translational Sciences