Spinal Cord Chip
Human spinal nervous tissue cells grown together with vascular cells in the Spinal Cord-Chip, developed at Cedars-Sinai in collaboration with Emulate, Inc., for amyotrophic lateral sclerosis disease (ALS) research. Two compartments contain spinal neurons (green) in the top channel and microcapillary cells (red) in the vascular channel. The vascular channel forms a hollow tube that allows media or blood to be flowed through, mimicking the delivery of nutrients and drugs into the nervous tissue. Each chip contains cells specifically generated from an individual patient’s stem cells. Studies are underway in chips generated from ALS patients, with the goal of uncovering biomarkers of disease and aiding in development of experimental treatments.
Credit: Cedars-Sinai Photo/Samuel Sances
Spinal Cord Chip
Human spinal nervous tissue cells grown together with vascular cells in the Spinal Cord-Chip, developed at Cedars-Sinai in collaboration with Emulate, Inc., for amyotrophic lateral sclerosis disease (ALS) research. Two compartments contain spinal neurons (green) in the top channel and microcapillary cells (red) in the vascular channel. The vascular channel forms a hollow tube that allows media or blood to be flowed through, mimicking the delivery of nutrients and drugs into the nervous tissue. Each chip contains cells specifically generated from an individual patient’s stem cells. Studies are underway in chips generated from ALS patients, with the goal of uncovering biomarkers of disease and aiding in development of experimental treatments.
Credit: Cedars-Sinai Photo/Samuel Sances