The Why Files
MezuNdubuisi_Olachi
Olachi J. Mezu-Ndubuisi, MD,OD / Assistant Professor, Department of Pediatrics and Ophthalmology
Retinal Imaging System
Retinal image of fluorescein angiogram (FA) done on a live, anesthetized 24 day old mouse exposed to 5 days of oxygen at one week of age. The image shows dilated and tortuous blood vessels, as well as obliteration of newly formed vessels. In vivo retinal imaging is a novel non-invasive method of studying Retinopathy of Prematurity (ROP) in a mouse model that shows unique abnormalities (arterial tortuosity, venous dilation, capillary sparsity) that were previously challenging to distinguish. ROP is an eye disease affecting premature newborns exposed to high levels of oxygen that can cause blindness.
MezuNdubuisi_Olachi
Olachi J. Mezu-Ndubuisi, MD,OD / Assistant Professor, Department of Pediatrics and Ophthalmology
Retinal Imaging System
Retinal image of fluorescein angiogram (FA) done on a live, anesthetized 24 day old mouse exposed to 5 days of oxygen at one week of age. The image shows dilated and tortuous blood vessels, as well as obliteration of newly formed vessels. In vivo retinal imaging is a novel non-invasive method of studying Retinopathy of Prematurity (ROP) in a mouse model that shows unique abnormalities (arterial tortuosity, venous dilation, capillary sparsity) that were previously challenging to distinguish. ROP is an eye disease affecting premature newborns exposed to high levels of oxygen that can cause blindness.