University of Brighton Doctoral College
17. Fernando Perez - Development of a sensor optimised for enzyme entrapment and consequent urinalysis
Around 12% of the adult population suffer with Overactive Bladder (OAB), experiencing symptoms such as urinary urgency and incontinence, resulting in a significant decrease in quality of life.
The bladder is regulated by release of signalling molecules such as Acetylcholine (ACh), Adenosine Triphosphate (ATP), and Nitric Oxide (NO) from the inner lining of the bladder. Biosensors can be used to dynamically detect the changes in the concentration of these molecules directly in the urological environment.
This research evaluates different strategies for biosensor fabrication using glucose oxidase (GOx) as an example enzyme attached to an electrode so that glucose can be measured.
17. Fernando Perez - Development of a sensor optimised for enzyme entrapment and consequent urinalysis
Around 12% of the adult population suffer with Overactive Bladder (OAB), experiencing symptoms such as urinary urgency and incontinence, resulting in a significant decrease in quality of life.
The bladder is regulated by release of signalling molecules such as Acetylcholine (ACh), Adenosine Triphosphate (ATP), and Nitric Oxide (NO) from the inner lining of the bladder. Biosensors can be used to dynamically detect the changes in the concentration of these molecules directly in the urological environment.
This research evaluates different strategies for biosensor fabrication using glucose oxidase (GOx) as an example enzyme attached to an electrode so that glucose can be measured.