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Filimelnotide Acetate | CAS Pending | Melanocortin Receptor Agonist for Endocrine and Metabolic Research

Product Description

Filimelnotide acetate is a synthetic peptide that functions as a melanocortin receptor (MC) agonist, targeting receptors such as MC1R, MC3R, and MC4R, which are essential for energy homeostasis, pigmentation control, and neuroendocrine regulation.

This compound mimics the biological activity of endogenous melanocortins, including α-MSH and ACTH derivatives, by binding to G protein–coupled melanocortin receptors. Activation of these receptors triggers downstream signaling through cyclic AMP (cAMP) and protein kinase A (PKA) pathways, leading to modulation of metabolic rate, appetite control, and inflammatory balance.

In research contexts, Filimelnotide acetate is widely employed to investigate melanocortin system dynamics, obesity-related signaling, and neuroendocrine peptide regulation. Studies have shown that the compound stimulates melanocortin-induced pathways associated with thermogenesis, fat oxidation, and appetite suppression.

Beyond metabolic studies, Filimelnotide acetate also offers value in pigmentation research, as the melanocortin system influences melanin biosynthesis through MC1R activation. This makes it an important molecular tool for elucidating pigment cell biology and photoresponse regulation.

Overall, Filimelnotide acetate provides researchers with a precise and reliable agent to explore the roles of melanocortin receptors in both central nervous system (CNS) and peripheral endocrine signaling.

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Uploaded on October 19, 2025